| Year |
Citation |
Score |
| 2023 |
Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W, Watts GFM, Weisenfeld D, Nayar S, Rangel-Moreno J, Meednu N, Marks KE, Mantel I, ... ... Perlman H, et al. Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. Nature. PMID 37938773 DOI: 10.1038/s41586-023-06708-y |
0.31 |
|
| 2023 |
Montgomery AB, Chen SY, Wang Y, Gadhvi G, Mayr MG, Cuda CM, Dominguez S, Moradeke Makinde HK, Gurra MG, Misharin AV, Mandelin AM, Ruderman EM, Thakrar A, Brar S, Carns M, ... ... Perlman H, et al. Tissue-resident, extravascular Ly6c monocytes are critical for inflammation in the synovium. Cell Reports. 42: 112513. PMID 37204925 DOI: 10.1016/j.celrep.2023.112513 |
0.306 |
|
| 2020 |
Do-Umehara HC, Chen C, Zhang Q, Misharin AV, Abdala-Valencia H, Casalino-Matsuda SM, Reyfman PA, Anekalla KR, Gonzalez-Gonzalez FJ, Sala MA, Peng C, Wu P, Wong CCL, Kalhan R, Bharat A, ... Perlman H, et al. Epithelial cell-specific loss of function of causes a spontaneous COPD-like phenotype and up-regulates expression in mice. Science Advances. 6: eabb7238. PMID 32851183 DOI: 10.1126/Sciadv.Abb7238 |
0.348 |
|
| 2019 |
Droho S, Cuda CM, Perlman H, Lavine JA. Monocyte-Derived Macrophages Are Necessary for Beta-Adrenergic Receptor-Driven Choroidal Neovascularization Inhibition. Investigative Ophthalmology & Visual Science. 60: 5059-5069. PMID 31800964 DOI: 10.1167/Iovs.19-28165 |
0.303 |
|
| 2019 |
Joshi N, Watanabe S, Verma R, Jablonski RP, Chen CI, Cheresh P, Markov NS, Reyfman PA, McQuattie-Pimentel AC, Sichizya L, Lu Z, Piseaux R, Kirchenbuechler D, Flozak AS, Gottardi CJ, ... ... Perlman H, et al. A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signaling in monocyte-derived alveolar macrophages. The European Respiratory Journal. PMID 31601718 DOI: 10.1183/13993003.00646-2019 |
0.336 |
|
| 2019 |
Croft AP, Campos J, Jansen K, Turner JD, Marshall J, Attar M, Savary L, Wehmeyer C, Naylor AJ, Kemble S, Begum J, Dürholz K, Perlman H, Barone F, McGettrick HM, et al. Distinct fibroblast subsets drive inflammation and damage in arthritis. Nature. PMID 31142839 DOI: 10.1038/S41586-019-1263-7 |
0.417 |
|
| 2019 |
Zhang F, Wei K, Slowikowski K, Fonseka CY, Rao DA, Kelly S, Goodman SM, Tabechian D, Hughes LB, Salomon-Escoto K, Watts GFM, Jonsson AH, Rangel-Moreno J, Meednu N, Rozo C, ... ... Perlman H, et al. Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry. Nature Immunology. PMID 31061532 DOI: 10.1038/S41590-019-0378-1 |
0.41 |
|
| 2019 |
Montgomery A, Winter D, Perlman H. Sat0106 Novel Subclass Of Intravascular Non-Classical Synovial Monocytes Are Critical For Rheumatoid Arthritis Annals of the Rheumatic Diseases. 78: 1119-1120. DOI: 10.1136/Annrheumdis-2019-Eular.8320 |
0.362 |
|
| 2019 |
Mandelin A, Bian S, Dominguez S, Ruderman E, Cuda C, Winter D, Perlman H. Op0294 Transcriptional Profiling Of Ra Patients Synovial Tissue Reveals Targets For Precision Medicine Annals of the Rheumatic Diseases. 78: 228-228. DOI: 10.1136/Annrheumdis-2019-Eular.8317 |
0.395 |
|
| 2018 |
Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, Adbala-Valencia H, ... ... Perlman H, et al. Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis. Cell Metabolism. PMID 30318339 DOI: 10.1016/J.Cmet.2018.09.019 |
0.365 |
|
| 2018 |
Coates BM, Staricha KL, Koch CM, Cheng Y, Shumaker DK, Budinger GRS, Perlman H, Misharin AV, Ridge KM. Inflammatory Monocytes Drive Influenza A Virus-Mediated Lung Injury in Juvenile Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 29445006 DOI: 10.4049/Jimmunol.1701543 |
0.37 |
|
| 2018 |
Mandelin AM, Homan PJ, Shaffer AM, Cuda CM, Dominguez ST, Bacalao E, Carns M, Hinchcliff M, Lee J, Aren K, Thakrar A, Montgomery AB, Louis Bridges S, Bathon JM, Atkinson JP, ... ... Perlman H, et al. Transcriptional Profiling of Synovial Macrophages using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 29439295 DOI: 10.1002/Art.40453 |
0.377 |
|
| 2018 |
Mike E, Cuda C, Makinde H, Perlman H, Putterman C. II-02 Neuropsychiatric lupus is dependent on lipocalin-2 Lupus Science & Medicine. 5. DOI: 10.1136/Lupus-2018-Lsm.101 |
0.388 |
|
| 2018 |
Perlman H. AB0227 Transcriptional profiling of synovial macrophages using minimally invasive ultrasound-guided synovial biopsies in rheumatoid arthritis Annals of the Rheumatic Diseases. 77: 1297-1297. DOI: 10.1136/Annrheumdis-2018-Eular.7594 |
0.38 |
|
| 2017 |
Tsai F, Homan PJ, Agrawal H, Misharin AV, Abdala-Valencia H, Haines GK, Dominguez S, Bloomfield CL, Saber R, Chang A, Mohan C, Hutcheson J, Davidson A, Budinger GRS, Bouillet P, ... ... Perlman H, et al. Bim suppresses the development of SLE by limiting myeloid inflammatory responses. The Journal of Experimental Medicine. PMID 29114065 DOI: 10.1084/Jem.20170479 |
0.769 |
|
| 2017 |
MacLauchlan S, Zuriaga MA, Fuster JJ, Cuda CM, Jonason J, Behzadi F, Duffen JP, Haines GK, Aprahamian T, Perlman H, Walsh K. Genetic deficiency of Wnt5a diminishes disease severity in a murine model of rheumatoid arthritis. Arthritis Research & Therapy. 19: 166. PMID 28724439 DOI: 10.1186/S13075-017-1375-0 |
0.426 |
|
| 2017 |
Misharin AV, Morales-Nebreda L, Reyfman PA, Cuda CM, Walter JM, McQuattie-Pimentel AC, Chen CI, Anekalla KR, Joshi N, Williams KJN, Abdala-Valencia H, Yacoub TJ, Chi M, Chiu S, Gonzalez-Gonzalez FJ, ... ... Perlman H, et al. Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span. The Journal of Experimental Medicine. PMID 28694385 DOI: 10.1084/Jem.20162152 |
0.301 |
|
| 2017 |
Ratsimandresy RA, Chu LH, Khare S, de Almeida L, Gangopadhyay A, Indramohan M, Misharin AV, Greaves DR, Perlman H, Dorfleutner A, Stehlik C. The PYRIN domain-only protein POP2 inhibits inflammasome priming and activation. Nature Communications. 8: 15556. PMID 28580931 DOI: 10.1038/Ncomms15556 |
0.399 |
|
| 2017 |
Huang QQ, Birket R, Doyle RE, Haines GK, Perlman H, Shi B, Homan P, Xing L, Pope RM. Increased F4/80(hi) macrophages is associated with suppression of serum transfer induced arthritis in mice with Flip reduced in myeloid cells. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28511285 DOI: 10.1002/Art.40151 |
0.479 |
|
| 2017 |
Perlman H, Tsa F, Cuda C, Homan P, Winter D. 9 Bim suppresses the development of sle by limiting macrophage inflammatory responses Lupus Science & Medicine. 4. DOI: 10.1136/Lupus-2017-000215.9 |
0.478 |
|
| 2016 |
Zheng F, Perlman H, Matthys P, Wen Y, Lahoutte T, Muyldermans S, Lu S, De Baetselier P, Schoonooghe S, Devoogdt N, Raes G. Specificity Evaluation and Disease Monitoring in Arthritis Imaging with Complement Receptor of the Ig superfamily targeting Nanobodies. Scientific Reports. 6: 35966. PMID 27779240 DOI: 10.1038/Srep35966 |
0.41 |
|
| 2016 |
Ross EA, Naylor AJ, O'Neil JD, Crowley T, Ridley ML, Crowe J, Smallie T, Tang TJ, Turner JD, Norling LV, Dominguez S, Perlman H, Verrills NM, Kollias G, Vitek MP, et al. Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression. Annals of the Rheumatic Diseases. PMID 27597652 DOI: 10.1136/Annrheumdis-2016-209424 |
0.411 |
|
| 2016 |
Cuda CM, Pope RM, Perlman H. The inflammatory role of phagocyte apoptotic pathways in rheumatic diseases. Nature Reviews. Rheumatology. 12: 543-58. PMID 27549026 DOI: 10.1038/Nrrheum.2016.132 |
0.439 |
|
| 2016 |
Archer AM, Saber R, Rose S, Shaffer A, Misharin AV, Tsai F, Haines Iii GK, Dominguez S, Eren M, Vaughan DE, Cuda CM, Perlman H. ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model. Journal of Translational Medicine. 14: 170. PMID 27287704 DOI: 10.1186/S12967-016-0912-Y |
0.451 |
|
| 2016 |
Bharat A, Bhorade SM, Morales-Nebreda L, McQuattie-Pimentel AC, Soberanes S, Ridge K, DeCamp MM, Mestan KK, Perlman H, Budinger GR, Misharin AV. Flow Cytometry Reveals Similarities Between Lung Macrophages in Humans and Mice. American Journal of Respiratory Cell and Molecular Biology. 54: 147-9. PMID 26274047 DOI: 10.1165/Rcmb.2015-0147Le |
0.328 |
|
| 2015 |
Cuda CM, Misharin AV, Khare S, Saber R, Tsai F, Archer AM, Homan PJ, Haines GK, Hutcheson J, Dorfleutner A, Budinger GR, Stehlik C, Perlman H. Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner. Arthritis Research & Therapy. 17: 291. PMID 26471282 DOI: 10.1186/S13075-015-0794-Z |
0.75 |
|
| 2015 |
Morales-Nebreda L, Misharin AV, Perlman H, Budinger GR. The heterogeneity of lung macrophages in the susceptibility to disease. European Respiratory Review : An Official Journal of the European Respiratory Society. 24: 505-9. PMID 26324812 DOI: 10.1183/16000617.0031-2015 |
0.334 |
|
| 2015 |
Duffau P, Menn-Josephy H, Cuda CM, Dominguez S, Aprahamian TR, Watkins AA, Yasuda K, Monach P, Lafyatis R, Rice LM, Haines GK, Gravallese EM, Baum R, Richez C, Perlman H, et al. Interferon Regulatory Factor 5 Promotes Inflammatory Arthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26315890 DOI: 10.1002/Art.39321 |
0.371 |
|
| 2015 |
de Almeida L, Khare S, Misharin AV, Patel R, Ratsimandresy RA, Wallin MC, Perlman H, Greaves DR, Hoffman HM, Dorfleutner A, Stehlik C. The PYRIN Domain-only Protein POP1 Inhibits Inflammasome Assembly and Ameliorates Inflammatory Disease. Immunity. 43: 264-76. PMID 26275995 DOI: 10.1016/J.Immuni.2015.07.018 |
0.395 |
|
| 2015 |
Huang QQ, Perlman H, Birkett R, Doyle R, Fang D, Haines GK, Robinson W, Datta S, Huang Z, Li QZ, Phee H, Pope RM. CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis. Nature Communications. 6: 7086. PMID 25963626 DOI: 10.1038/Ncomms8086 |
0.466 |
|
| 2015 |
Xia Y, Herlitz LC, Gindea S, Wen J, Pawar RD, Misharin A, Perlman H, Wu L, Wu P, Michaelson JS, Burkly LC, Putterman C. Deficiency of fibroblast growth factor-inducible 14 (Fn14) preserves the filtration barrier and ameliorates lupus nephritis. Journal of the American Society of Nephrology : Jasn. 26: 1053-70. PMID 25270074 DOI: 10.1681/Asn.2014030233 |
0.437 |
|
| 2015 |
Morales-Nebreda LI, Rogel MR, Eisenberg JL, Hamill KJ, Soberanes S, Nigdelioglu R, Chi M, Cho T, Radigan KA, Ridge KM, Misharin AV, Woychek A, Hopkinson S, Perlman H, Mutlu GM, et al. Lung-specific loss of α3 laminin worsens bleomycin-induced pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 52: 503-12. PMID 25188360 DOI: 10.1165/Rcmb.2014-0057Oc |
0.317 |
|
| 2015 |
Ross E, Smallie T, Naylor A, Desanti G, Crowe J, O’Neil J, Turner J, Yemm A, Norling L, Perlman H, Verrills N, Filer A, Dean J, Buckley C, Clark A. A8.1 Tristetraprolin is a novel therapeutic target for rheumatoid arthritis Annals of the Rheumatic Diseases. 74. DOI: 10.1136/Annrheumdis-2015-207259.186 |
0.476 |
|
| 2014 |
Misharin AV, Cuda CM, Saber R, Turner JD, Gierut AK, Haines GK, Berdnikovs S, Filer A, Clark AR, Buckley CD, Mutlu GM, Budinger GR, Perlman H. Nonclassical Ly6C(-) monocytes drive the development of inflammatory arthritis in mice. Cell Reports. 9: 591-604. PMID 25373902 DOI: 10.1016/j.celrep.2014.09.032 |
0.313 |
|
| 2014 |
Chiarella SE, Soberanes S, Urich D, Morales-Nebreda L, Nigdelioglu R, Green D, Young JB, Gonzalez A, Rosario C, Misharin AV, Ghio AJ, Wunderink RG, Donnelly HK, Radigan KA, Perlman H, et al. β₂-Adrenergic agonists augment air pollution-induced IL-6 release and thrombosis. The Journal of Clinical Investigation. 124: 2935-46. PMID 24865431 DOI: 10.1172/Jci75157 |
0.338 |
|
| 2014 |
Cuda CM, Misharin AV, Gierut AK, Saber R, Haines GK, Hutcheson J, Hedrick SM, Mohan C, Budinger GS, Stehlik C, Perlman H. Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation. Journal of Immunology (Baltimore, Md. : 1950). 192: 5548-60. PMID 24808358 DOI: 10.4049/Jimmunol.1400122 |
0.746 |
|
| 2014 |
Khare S, Ratsimandresy RA, de Almeida L, Cuda CM, Rellick SL, Misharin AV, Wallin MC, Gangopadhyay A, Forte E, Gottwein E, Perlman H, Reed JC, Greaves DR, Dorfleutner A, Stehlik C. The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses. Nature Immunology. 15: 343-53. PMID 24531343 DOI: 10.1038/Ni.2829 |
0.331 |
|
| 2014 |
Huang QQ, Birkett R, Koessler RE, Cuda CM, Haines GK, Jin JP, Perlman H, Pope RM. Fas signaling in macrophages promotes chronicity in K/BxN serum-induced arthritis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 68-77. PMID 24431281 DOI: 10.1002/Art.38198 |
0.378 |
|
| 2013 |
Qiu Q, Zheng Z, Chang L, Zhao YS, Tan C, Dandekar A, Zhang Z, Lin Z, Gui M, Li X, Zhang T, Kong Q, Li H, Chen S, Chen A, ... ... Perlman H, et al. Toll-like receptor-mediated IRE1α activation as a therapeutic target for inflammatory arthritis. The Embo Journal. 32: 2477-90. PMID 23942232 DOI: 10.1038/Emboj.2013.183 |
0.474 |
|
| 2013 |
Rose S, Waters EA, Haney CR, Meade CT, Perlman H. High-resolution magnetic resonance imaging of ankle joints in murine arthritis discriminates inflammation and bone destruction in a quantifiable manner. Arthritis and Rheumatism. 65: 2279-89. PMID 23740612 DOI: 10.1002/Art.38030 |
0.356 |
|
| 2013 |
Misharin AV, Morales-Nebreda L, Mutlu GM, Budinger GR, Perlman H. Flow cytometric analysis of macrophages and dendritic cell subsets in the mouse lung. American Journal of Respiratory Cell and Molecular Biology. 49: 503-10. PMID 23672262 DOI: 10.1165/Rcmb.2013-0086Ma |
0.301 |
|
| 2013 |
Huang QQ, Koessler RE, Birkett R, Perlman H, Xing L, Pope RM. TLR2 deletion promotes arthritis through reduction of IL-10. Journal of Leukocyte Biology. 93: 751-9. PMID 23446149 DOI: 10.1189/jlb.0912473 |
0.376 |
|
| 2013 |
Sena LA, Li S, Jairaman A, Prakriya M, Ezponda T, Hildeman DA, Wang CR, Schumacker PT, Licht JD, Perlman H, Bryce PJ, Chandel NS. Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling. Immunity. 38: 225-36. PMID 23415911 DOI: 10.1016/J.Immuni.2012.10.020 |
0.317 |
|
| 2013 |
Yona S, Kim KW, Wolf Y, Mildner A, Varol D, Breker M, Strauss-Ayali D, Viukov S, Guilliams M, Misharin A, Hume DA, Perlman H, Malissen B, Zelzer E, Jung S. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity. 38: 79-91. PMID 23273845 DOI: 10.1016/J.Immuni.2012.12.001 |
0.326 |
|
| 2013 |
Rose S, Eren M, Murphy S, Zhang H, Thaxton CS, Chowaniec J, Waters EA, Meade TJ, Vaughan DE, Perlman H. A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis. Annals of the Rheumatic Diseases. 72: 89-95. PMID 22736097 DOI: 10.1136/Annrheumdis-2012-201431 |
0.438 |
|
| 2012 |
Misharin AV, Haines GK, Rose S, Gierut AK, Hotchkiss RS, Perlman H. Development of a new humanized mouse model to study acute inflammatory arthritis. Journal of Translational Medicine. 10: 190. PMID 22974474 DOI: 10.1186/1479-5876-10-190 |
0.445 |
|
| 2012 |
Huang QQ, Koessler RE, Birkett R, Dorfleutner A, Perlman H, Haines GK, Stehlik C, Nicchitta CV, Pope RM. Glycoprotein 96 perpetuates the persistent inflammation of rheumatoid arthritis. Arthritis and Rheumatism. 64: 3638-48. PMID 22777994 DOI: 10.1002/Art.34610 |
0.447 |
|
| 2012 |
Misharin AV, Saber R, Perlman H. Eosinophil contamination of thioglycollate-elicited peritoneal macrophage cultures skews the functional readouts of in vitro assays. Journal of Leukocyte Biology. 92: 325-31. PMID 22706315 DOI: 10.1189/Jlb.1111560 |
0.331 |
|
| 2012 |
Cuda CM, Agrawal H, Misharin AV, Haines GK, Hutcheson J, Weber E, Schoenfeldt JA, Mohan C, Pope RM, Perlman H. Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice. Arthritis and Rheumatism. 64: 808-20. PMID 22143975 DOI: 10.1002/Art.34317 |
0.762 |
|
| 2012 |
Mavers M, Cuda CM, Misharin AV, Gierut AK, Agrawal H, Weber E, Novack DV, Haines GK, Balomenos D, Perlman H. Cyclin-dependent kinase inhibitor p21, via its C-terminal domain, is essential for resolution of murine inflammatory arthritis. Arthritis and Rheumatism. 64: 141-52. PMID 21898359 DOI: 10.1002/Art.33311 |
0.436 |
|
| 2011 |
Misharin AV, Scott Budinger GR, Perlman H. The lung macrophage: a Jack of all trades. American Journal of Respiratory and Critical Care Medicine. 184: 497-8. PMID 21885631 DOI: 10.1164/Rccm.201107-1343Ed |
0.351 |
|
| 2010 |
Huang QQ, Perlman H, Huang Z, Birkett R, Kan L, Agrawal H, Misharin A, Gurbuxani S, Crispino JD, Pope RM. FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis. Blood. 116: 4968-77. PMID 20724542 DOI: 10.1182/Blood-2009-11-252841 |
0.465 |
|
| 2010 |
Perlman H, Pope RM. The synovial lining micromass system: toward rheumatoid arthritis in a dish? Arthritis and Rheumatism. 62: 643-6. PMID 20187157 DOI: 10.1002/Art.27297 |
0.433 |
|
| 2010 |
Scatizzi JC, Hutcheson J, Pope RM, Firestein GS, Koch AE, Mavers M, Smason A, Agrawal H, Haines GK, Chandel NS, Hotchkiss RS, Perlman H. Bim-Bcl-2 homology 3 mimetic therapy is effective at suppressing inflammatory arthritis through the activation of myeloid cell apoptosis. Arthritis and Rheumatism. 62: 441-51. PMID 20112357 DOI: 10.1002/Art.27198 |
0.779 |
|
| 2009 |
Shroff EH, Snyder CM, Budinger GR, Jain M, Chew TL, Khuon S, Perlman H, Chandel NS. BH3 peptides induce mitochondrial fission and cell death independent of BAX/BAK. Plos One. 4: e5646. PMID 19468307 DOI: 10.1371/Journal.Pone.0005646 |
0.314 |
|
| 2009 |
Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H. The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages. European Journal of Immunology. 39: 820-5. PMID 19189309 DOI: 10.1002/Eji.200838683 |
0.759 |
|
| 2009 |
Peck-Palmer OM, Unsinger J, Chang KC, McDonough JS, Perlman H, McDunn JE, Hotchkiss RS. Modulation of the Bcl-2 family blocks sepsis-induced depletion of dendritic cells and macrophages. Shock (Augusta, Ga.). 31: 359-66. PMID 18838943 DOI: 10.1097/Shk.0B013E31818Ba2A2 |
0.434 |
|
| 2008 |
Hutcheson J, Perlman H. BH3-only proteins in rheumatoid arthritis: potential targets for therapeutic intervention. Oncogene. 27: S168-75. PMID 19641502 DOI: 10.1038/Onc.2009.54 |
0.76 |
|
| 2008 |
Hutcheson J, Scatizzi JC, Siddiqui AM, Haines GK, Wu T, Li QZ, Davis LS, Mohan C, Perlman H. Combined deficiency of proapoptotic regulators Bim and Fas results in the early onset of systemic autoimmunity. Immunity. 28: 206-17. PMID 18275831 DOI: 10.1016/J.Immuni.2007.12.015 |
0.792 |
|
| 2008 |
Hutcheson J, Perlman H. Apoptotic Regulators and RA Current Rheumatology Reviews. 4: 254-258. DOI: 10.2174/157339708786263870 |
0.723 |
|
| 2007 |
Hutcheson J, Perlman H. Loss of Bim results in abnormal accumulation of mature CD4-CD8-CD44-CD25- thymocytes. Immunobiology. 212: 629-36. PMID 17869640 DOI: 10.1016/J.Imbio.2007.05.003 |
0.685 |
|
| 2007 |
Scatizzi JC, Hutcheson J, Bickel E, Haines GK, Perlman H. Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis. Arthritis Research & Therapy. 9: R49. PMID 17509138 DOI: 10.1186/Ar2204 |
0.815 |
|
| 2007 |
Brunelle JK, Shroff EH, Perlman H, Strasser A, Moraes CT, Flavell RA, Danial NN, Keith B, Thompson CB, Chandel NS. Loss of Mcl-1 protein and inhibition of electron transport chain together induce anoxic cell death. Molecular and Cellular Biology. 27: 1222-35. PMID 17145774 DOI: 10.1128/Mcb.01535-06 |
0.365 |
|
| 2007 |
Albee L, Shi B, Perlman H. Aspartic protease and caspase 3/7 activation are central for macrophage apoptosis following infection with Escherichia coli. Journal of Leukocyte Biology. 81: 229-37. PMID 17023557 DOI: 10.1189/Jlb.0506358 |
0.369 |
|
| 2006 |
Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis. Arthritis and Rheumatism. 54: 3182-93. PMID 17009248 DOI: 10.1002/Art.22133 |
0.794 |
|
| 2006 |
Aprahamian T, Bonegio R, Rizzo J, Perlman H, Lefer DJ, Rifkin IR, Walsh K. Simvastatin treatment ameliorates autoimmune disease associated with accelerated atherosclerosis in a murine lupus model. Journal of Immunology (Baltimore, Md. : 1950). 177: 3028-34. PMID 16920939 DOI: 10.4049/Jimmunol.177.5.3028 |
0.408 |
|
| 2006 |
Woods JM, Klosowska K, Spoden DJ, Stumbo NG, Paige DJ, Scatizzi JC, Volin MV, Rao MS, Perlman H. A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis. Arthritis Research & Therapy. 8: R113. PMID 16846525 DOI: 10.1186/Ar1999 |
0.787 |
|
| 2006 |
Scatizzi JC, Hutcheson J, Bickel E, Woods JM, Klosowska K, Moore TL, Haines GK, Perlman H. p21Cip1 is required for the development of monocytes and their response to serum transfer-induced arthritis. The American Journal of Pathology. 168: 1531-41. PMID 16651620 DOI: 10.2353/Ajpath.2006.050555 |
0.792 |
|
| 2006 |
Albee L, Perlman H. E. coli infection induces caspase dependent degradation of NF-κB and reduces the inflammatory response in macrophages Inflammation Research. 55: 2-9. PMID 16328105 DOI: 10.1007/S00011-005-0001-9 |
0.35 |
|
| 2005 |
Liu H, Eksarko P, Temkin V, Haines GK, Perlman H, Koch AE, Thimmapaya B, Pope RM. Mcl-1 is essential for the survival of synovial fibroblasts in rheumatoid arthritis. Journal of Immunology (Baltimore, Md. : 1950). 175: 8337-45. PMID 16339575 DOI: 10.4049/Jimmunol.175.12.8337 |
0.474 |
|
| 2005 |
Coultas L, Bouillet P, Loveland KL, Meachem S, Perlman H, Adams JM, Strasser A. Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis. The Embo Journal. 24: 3963-73. PMID 16270031 DOI: 10.1038/Sj.Emboj.7600857 |
0.452 |
|
| 2005 |
Hutcheson J, Scatizzi JC, Bickel E, Brown NJ, Bouillet P, Strasser A, Perlman H. Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis. The Journal of Experimental Medicine. 201: 1949-60. PMID 15967824 DOI: 10.1084/Jem.20041484 |
0.78 |
|
| 2004 |
Bai S, Liu H, Chen KH, Eksarko P, Perlman H, Moore TL, Pope RM. NF-kappaB-regulated expression of cellular FLIP protects rheumatoid arthritis synovial fibroblasts from tumor necrosis factor alpha-mediated apoptosis. Arthritis and Rheumatism. 50: 3844-55. PMID 15593196 DOI: 10.1002/Art.20680 |
0.431 |
|
| 2004 |
Brown NJ, Hutcheson J, Bickel E, Scatizzi JC, Albee LD, Haines GK, Eslick J, Bradley K, Taricone E, Perlman H. Fas death receptor signaling represses monocyte numbers and macrophage activation in vivo. Journal of Immunology (Baltimore, Md. : 1950). 173: 7584-93. PMID 15585886 DOI: 10.4049/Jimmunol.173.12.7584 |
0.787 |
|
| 2004 |
Eslick J, Scatizzi JC, Albee L, Bickel E, Bradley K, Perlman H. IL-4 and IL-10 inhibition of spontaneous monocyte apoptosis is associated with Flip upregulation. Inflammation. 28: 139-45. PMID 15527169 DOI: 10.1023/B:Ifla.0000039560.00231.Cd |
0.77 |
|
| 2004 |
Yang J, Sato K, Aprahamian T, Brown NJ, Hutcheson J, Bialik A, Perlman H, Walsh K. Endothelial overexpression of Fas ligand decreases atherosclerosis in apolipoprotein E-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 24: 1466-73. PMID 15178561 DOI: 10.1161/01.Atv.0000134402.94963.2F |
0.736 |
|
| 2004 |
Liu H, Ma Y, Pagliari LJ, Perlman H, Yu C, Lin A, Pope RM. TNF-alpha-induced apoptosis of macrophages following inhibition of NF-kappa B: a central role for disruption of mitochondria. Journal of Immunology (Baltimore, Md. : 1950). 172: 1907-15. PMID 14734776 DOI: 10.4049/Jimmunol.172.3.1907 |
0.35 |
|
| 2004 |
Bradley K, Scatizzi JC, Fiore S, Shamiyeh E, Koch AE, Firestein GS, Gorges LL, Kuntsman K, Pope RM, Moore TL, Han J, Perlman H. Retinoblastoma suppression of matrix metalloproteinase 1, but not interleukin-6, through a p38-dependent pathway in rheumatoid arthritis synovial fibroblasts. Arthritis and Rheumatism. 50: 78-87. PMID 14730602 DOI: 10.1002/Art.11482 |
0.784 |
|
| 2003 |
Perlman H, Nguyen N, Liu H, Eslick J, Esser S, Walsh K, Moore TL, Pope RM. Rheumatoid arthritis synovial fluid macrophages express decreased tumor necrosis factor-related apoptosis-inducing ligand R2 and increased decoy receptor tumor necrosis factor-related apoptosis-inducing ligand R3. Arthritis and Rheumatism. 48: 3096-101. PMID 14613271 DOI: 10.1002/Art.11302 |
0.367 |
|
| 2003 |
Yang J, Jones SP, Suhara T, Greer JJ, Ware PD, Nguyen NP, Perlman H, Nelson DP, Lefer DJ, Walsh K. Endothelial cell overexpression of fas ligand attenuates ischemia-reperfusion injury in the heart. The Journal of Biological Chemistry. 278: 15185-91. PMID 12576484 DOI: 10.1074/Jbc.M211707200 |
0.348 |
|
| 2003 |
Steer SA, Moran JM, Maggi LB, Buller RM, Perlman H, Corbett JA. Regulation of cyclooxygenase-2 expression by macrophages in response to double-stranded RNA and viral infection. Journal of Immunology (Baltimore, Md. : 1950). 170: 1070-6. PMID 12517975 DOI: 10.4049/Jimmunol.170.2.1070 |
0.334 |
|
| 2003 |
Perlman H, Bradley K, Liu H, Cole S, Shamiyeh E, Smith RC, Walsh K, Fiore S, Koch AE, Firestein GS, Haines GK, Pope RM. IL-6 and matrix metalloproteinase-1 are regulated by the cyclin-dependent kinase inhibitor p21 in synovial fibroblasts. Journal of Immunology (Baltimore, Md. : 1950). 170: 838-45. PMID 12517948 DOI: 10.4049/Jimmunol.170.2.838 |
0.448 |
|
| 2002 |
Perlman H, Liu H, Georganas C, Koch AE, Shamiyeh E, Haines GK, Pope RM. Differential expression pattern of the antiapoptotic proteins, Bcl-2 and FLIP, in experimental arthritis. Arthritis and Rheumatism. 44: 2899-908. PMID 11762951 DOI: 10.1002/1529-0131(200112)44:12<2899::Aid-Art478>3.0.Co;2-X |
0.39 |
|
| 2001 |
Perlman H, Pagliari LJ, Nguyen N, Bradley K, Liu H, Pope RM. The Fas-FasL death receptor and PI3K pathways independently regulate monocyte homeostasis. European Journal of Immunology. 31: 2421-30. PMID 11500826 DOI: 10.1002/1521-4141(200108)31:8<2421::Aid-Immu2421>3.0.Co;2-W |
0.373 |
|
| 2001 |
Georganas C, Liu H, Perlman H, Hoffmann A, Thimmapaya B, Pope RM. Regulation of IL-6 and IL-8 expression in rheumatoid arthritis synovial fibroblasts: the dominant role for NF-kappa B but not C/EBP beta or c-Jun. Journal of Immunology (Baltimore, Md. : 1950). 165: 7199-206. PMID 11120852 DOI: 10.4049/Jimmunol.165.12.7199 |
0.334 |
|
| 2000 |
Pagliari LJ, Perlman H, Liu H, Pope RM. Macrophages require constitutive NF-kappaB activation to maintain A1 expression and mitochondrial homeostasis. Molecular and Cellular Biology. 20: 8855-65. PMID 11073986 DOI: 10.1128/Mcb.20.23.8855-8865.2000 |
0.373 |
|
| 2000 |
Perlman H, Sata M, Krasinski K, Dorai T, Buttyan R, Walsh K. Adenovirus-encoded hammerhead ribozyme to Bcl-2 inhibits neointimal hyperplasia and induces vascular smooth muscle cell apoptosis. Cardiovascular Research. 45: 570-8. PMID 10728378 DOI: 10.1016/S0008-6363(99)00346-6 |
0.379 |
|
| 1999 |
Perlman H, Pagliari LJ, Georganas C, Mano T, Walsh K, Pope RM. FLICE-inhibitory protein expression during macrophage differentiation confers resistance to fas-mediated apoptosis. The Journal of Experimental Medicine. 190: 1679-88. PMID 10587358 DOI: 10.1084/Jem.190.11.1679 |
0.459 |
|
| 1999 |
Perlman H, Luo Z, Krasinski K, Le Roux A, Mahfoudi A, Smith RC, Branellec D, Walsh K. Adenovirus-mediated delivery of the Gax transcription factor to rat carotid arteries inhibits smooth muscle proliferation and induces apoptosis. Gene Therapy. 6: 758-63. PMID 10505098 DOI: 10.1038/Sj.Gt.3300893 |
0.302 |
|
| 1999 |
Dorai T, Perlman H, Walsh K, Shabsigh A, Goluboff ET, Olsson CA, Buttyan R. A recombinant defective adenoviral agent expressing anti-bcl-2 ribozyme promotes apoptosis of bcl-2-expressing human prostate cancer cells. International Journal of Cancer. 82: 846-52. PMID 10446452 DOI: 10.1002/(Sici)1097-0215(19990909)82:6<846::Aid-Ijc13>3.0.Co;2-C |
0.318 |
|
| 1999 |
Pope RM, Lovis R, Mungre S, Perlman H, Koch AE, Haines GK. C/EBP beta in rheumatoid arthritis: correlation with inflammation, not disease specificity. Clinical Immunology (Orlando, Fla.). 91: 271-82. PMID 10370372 DOI: 10.1006/Clim.1999.4723 |
0.338 |
|
| 1998 |
Perlman H, Sata M, Le Roux A, Sedlak TW, Branellec D, Walsh K. Bax-mediated cell death by the Gax homeoprotein requires mitogen activation but is independent of cell cycle activity. The Embo Journal. 17: 3576-86. PMID 9649428 DOI: 10.1093/Emboj/17.13.3576 |
0.407 |
|
| 1998 |
Perlman H, Suzuki E, Simonson M, Smith RC, Walsh K. GATA-6 induces p21(Cip1) expression and G1 cell cycle arrest. The Journal of Biological Chemistry. 273: 13713-8. PMID 9593712 DOI: 10.1074/Jbc.273.22.13713 |
0.348 |
|
| 1998 |
Sata M, Perlman H, Muruve DA, Silver M, Ikebe M, Libermann TA, Oettgen P, Walsh K. Fas ligand gene transfer to the vessel wall inhibits neointima formation and overrides the adenovirus-mediated T cell response. Proceedings of the National Academy of Sciences of the United States of America. 95: 1213-7. PMID 9448311 DOI: 10.1073/Pnas.95.3.1213 |
0.331 |
|
| 1997 |
Walsh K, Perlman H. Cell cycle exit upon myogenic differentiation. Current Opinion in Genetics & Development. 7: 597-602. PMID 9388774 DOI: 10.1016/S0959-437X(97)80005-6 |
0.341 |
|
| 1997 |
Smith RC, Branellec D, Gorski DH, Guo K, Perlman H, Dedieu JF, Pastore C, Mahfoudi A, Denèfle P, Isner JM, Walsh K. p21CIP1-mediated inhibition of cell proliferation by overexpression of the gax homeodomain gene. Genes & Development. 11: 1674-89. PMID 9224717 DOI: 10.1101/Gad.11.13.1674 |
0.339 |
|
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