| Year |
Citation |
Score |
| 2023 |
Bourne N, Keith CA, Miller AL, Pyles RB, Cohen G, Milligan GN. Boosting of vaginal HSV-2-specific B and T cell responses by intravaginal therapeutic immunization results in diminished recurrent HSV-2 disease. Journal of Virology. e0066923. PMID 37655939 DOI: 10.1128/jvi.00669-23 |
0.462 |
|
| 2023 |
Goethals O, Kaptein SJF, Kesteleyn B, Bonfanti JF, Van Wesenbeeck L, Bardiot D, Verschoor EJ, Verstrepen BE, Fagrouch Z, Putnak JR, Kiemel D, Ackaert O, Straetemans R, Lachau-Durand S, Geluykens P, ... ... Milligan GN, et al. Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates. Nature. PMID 36922586 DOI: 10.1038/s41586-023-05790-6 |
0.314 |
|
| 2019 |
Banasik BN, Perry CL, Keith CA, Bourne N, Schäfer H, Milligan GN. Development of an anti-guinea pig CD4 monoclonal antibody for depletion of CD4+ T cells in vivo. Journal of Immunological Methods. 112654. PMID 31421081 DOI: 10.1016/J.Jim.2019.112654 |
0.489 |
|
| 2018 |
Bourne N, Perry CL, Banasik BN, Miller AL, White M, Pyles RB, Schäfer H, Milligan GN. Increased frequency of virus shedding by herpes simplex virus type 2-infected guinea pigs in the absence of CD4+ T lymphocytes. Journal of Virology. PMID 30463981 DOI: 10.1128/Jvi.01721-18 |
0.556 |
|
| 2018 |
Milligan GN, Schnierle BS, McAuley AJ, Beasley DWC. Defining a correlate of protection for chikungunya virus vaccines. Vaccine. PMID 30448337 DOI: 10.1016/J.Vaccine.2018.10.033 |
0.352 |
|
| 2018 |
Bourne N, Banasik BN, Perry CL, Miller AL, White M, Pyles RB, Milligan GN. Development of disease and immunity at the genital epithelium following intrarectal inoculation of male guinea pigs with herpes simplex virus type 2. Virology. 526: 180-188. PMID 30412859 DOI: 10.1016/J.Virol.2018.10.023 |
0.532 |
|
| 2018 |
Milligan GN, White M, Zavala D, Pyles RB, Sarathy VV, Barrett ADT, Bourne N. Spectrum of activity testing for therapeutics against all four dengue virus serotypes in AG129 mouse models: Proof-of-concept studies with the adenosine nucleoside inhibitor NITD-008. Antiviral Research. PMID 29665374 DOI: 10.1016/J.Antiviral.2018.04.012 |
0.409 |
|
| 2018 |
Reece LM, Beasley DW, Milligan GN, Sarathy VV, Barrett AD. Current status of Severe Fever with Thrombocytopenia Syndrome vaccine development. Current Opinion in Virology. 29: 72-78. PMID 29642053 DOI: 10.1016/J.Coviro.2018.03.005 |
0.382 |
|
| 2018 |
Veselenak RL, Milligan GN, Miller AL, Pyles RB, Bourne N. Transcriptional Analysis of the Guinea Pig Mucosal Immune Response to Intravaginal Infection with Herpes Simplex Virus Type 2. Virology. 518: 349-357. PMID 29604476 DOI: 10.1016/J.Virol.2018.03.019 |
0.495 |
|
| 2018 |
Hallam HJ, Hallam S, Rodriguez SE, Barrett ADT, Beasley DWC, Chua A, Ksiazek TG, Milligan GN, Sathiyamoorthy V, Reece LM. Baseline mapping of Lassa fever virology, epidemiology and vaccine research and development. Npj Vaccines. 3: 11. PMID 29581897 DOI: 10.1038/s41541-018-0049-5 |
0.39 |
|
| 2018 |
Sarathy VV, White M, Li L, Kaiser JA, Campbell GA, Milligan GN, Bourne N, Barrett ADT. Characterization of a murine model of non-lethal, symptomatic dengue virus infection. Scientific Reports. 8: 4900. PMID 29559699 DOI: 10.1038/S41598-018-22618-W |
0.44 |
|
| 2018 |
Rudra JS, Banasik BN, Milligan GN. A combined carrier-adjuvant system of peptide nanofibers and toll-like receptor agonists potentiates robust CD8+ T cell responses. Vaccine. 36: 438-441. PMID 29248267 DOI: 10.1016/J.Vaccine.2017.12.017 |
0.495 |
|
| 2017 |
Milligan GN, Vargas G, Vincent KL, Zhu Y, Bourne N, Motamedi M. Evaluation of immunological markers of ovine vaginal irritation: Implications for preclinical assessment of non-vaccine HIV preventive agents. Journal of Reproductive Immunology. 124: 38-43. PMID 29054075 DOI: 10.1016/J.Jri.2017.09.014 |
0.324 |
|
| 2017 |
Milligan GN, Sarathy VV, White MM, Greenberg MB, Campbell GA, Pyles RB, Barrett ADT, Bourne N. A lethal model of disseminated dengue virus type 1 infection in AG129 mice. The Journal of General Virology. PMID 28949904 DOI: 10.1099/Jgv.0.000923 |
0.452 |
|
| 2016 |
Perry C, Banasik B, Gorder SR, Xia J, Auclair S, Bourne N, Milligan GN. Detection of herpes simplex virus type 2 (HSV-2) -specific cell-mediated immune responses in Guinea pigs during latent HSV-2 genital infection. Journal of Immunological Methods. PMID 27659010 DOI: 10.1016/J.Jim.2016.09.004 |
0.554 |
|
| 2016 |
Satterfield BA, Dawes BE, Milligan GN. Status of vaccine research and development of vaccines for Nipah virus: Prepared for WHO PD-VAC July 30, 2015. Vaccine. PMID 26973068 DOI: 10.1016/J.Vaccine.2015.12.075 |
0.333 |
|
| 2015 |
Xie G, Luo H, Pang L, Peng BH, Winkelmann E, McGruder B, Hesse J, Whiteman M, Campbell G, Milligan GN, Cong Y, Barrett AD, Wang T. Dysregulation of TLR7 compromises innate and adaptive T cell responses and host resistance to an attenuated West Nile virus infection in old mice. Journal of Virology. PMID 26581984 DOI: 10.1128/Jvi.02488-15 |
0.588 |
|
| 2015 |
Sarathy VV, Milligan GN, Bourne N, Barrett AD. Mouse models of dengue virus infection for vaccine testing. Vaccine. PMID 26478201 DOI: 10.1016/J.Vaccine.2015.09.112 |
0.54 |
|
| 2015 |
Sarathy VV, Infante E, Li L, Campbell GA, Wang T, Paessler S, Beatty PR, Harris E, Milligan GN, Bourne N, Barrett AD. Characterization of lethal DENV-4 TVP-376 infection in mice lacking both alpha/beta and gamma interferon receptors (AG129) and comparison with the DENV-2 AG129 mouse model. The Journal of General Virology. PMID 26296350 DOI: 10.1099/Jgv.0.000246 |
0.496 |
|
| 2015 |
Milligan GN, Sarathy VV, Infante E, Li L, Campbell GA, Beatty PR, Harris E, Barrett AD, Bourne N. A Dengue Virus Type 4 Model of Disseminated Lethal Infection in AG129 Mice. Plos One. 10: e0125476. PMID 25938762 DOI: 10.1371/Journal.Pone.0125476 |
0.476 |
|
| 2015 |
Sarathy VV, White M, Li L, Gorder SR, Pyles RB, Campbell GA, Milligan GN, Bourne N, Barrett AD. A lethal murine infection model for dengue virus 3 in AG129 mice deficient in type I and II interferon receptors leads to systemic disease. Journal of Virology. 89: 1254-66. PMID 25392217 DOI: 10.1128/Jvi.01320-14 |
0.487 |
|
| 2014 |
Xia J, Veselenak RL, Gorder SR, Bourne N, Milligan GN. Virus-specific immune memory at peripheral sites of herpes simplex virus type 2 (HSV-2) infection in guinea pigs. Plos One. 9: e114652. PMID 25485971 DOI: 10.1371/Journal.Pone.0114652 |
0.494 |
|
| 2014 |
Fuchs J, Chu H, O'Day P, Pyles R, Bourne N, Das SC, Milligan GN, Barrett AD, Partidos CD, Osorio JE. Investigating the efficacy of monovalent and tetravalent dengue vaccine formulations against DENV-4 challenge in AG129 mice. Vaccine. 32: 6537-43. PMID 25239488 DOI: 10.1016/J.Vaccine.2014.08.087 |
0.399 |
|
| 2014 |
Winkelmann ER, Widman DG, Xia J, Johnson AJ, van Rooijen N, Mason PW, Bourne N, Milligan GN. Subcapsular sinus macrophages limit dissemination of West Nile virus particles after inoculation but are not essential for the development of West Nile virus-specific T cell responses. Virology. 450: 278-89. PMID 24503091 DOI: 10.1016/J.Virol.2013.12.021 |
0.514 |
|
| 2013 |
Xia J, Winkelmann ER, Gorder SR, Mason PW, Milligan GN. TLR3- and MyD88-dependent signaling differentially influences the development of West Nile virus-specific B cell responses in mice following immunization with RepliVAX WN, a single-cycle flavivirus vaccine candidate. Journal of Virology. 87: 12090-101. PMID 23986602 DOI: 10.1128/Jvi.01469-13 |
0.45 |
|
| 2012 |
Valencia F, Bubar MJ, Milligan G, Cunningham KA, Bourne N. Influence of methamphetamine on genital herpes simplex virus type 2 infection in a mouse model. Sexually Transmitted Diseases. 39: 720-5. PMID 22902670 DOI: 10.1097/Olq.0B013E31825Af129 |
0.505 |
|
| 2012 |
Winkelmann ER, Widman DG, Xia J, Ishikawa T, Miller-Kittrell M, Nelson MH, Bourne N, Scholle F, Mason PW, Milligan GN. Intrinsic adjuvanting of a novel single-cycle flavivirus vaccine in the absence of type I interferon receptor signaling. Vaccine. 30: 1465-75. PMID 22226862 DOI: 10.1016/J.Vaccine.2011.12.103 |
0.604 |
|
| 2011 |
Nelson MH, Bird MD, Chu CF, Johnson AJ, Friedrich BM, Allman WR, Milligan GN. Rapid clearance of herpes simplex virus type 2 by CD8+ T cells requires high level expression of effector T cell functions. Journal of Reproductive Immunology. 89: 10-7. PMID 21444117 DOI: 10.1016/J.Jri.2011.01.013 |
0.722 |
|
| 2010 |
Nelson MH, Winkelmann E, Ma Y, Xia J, Mason PW, Bourne N, Milligan GN. Immunogenicity of RepliVAX WN, a novel single-cycle West Nile virus vaccine. Vaccine. 29: 174-82. PMID 21055493 DOI: 10.1016/J.Vaccine.2010.10.069 |
0.557 |
|
| 2010 |
Vincent KL, Bell BA, Johnston RK, Stegall R, Vargas G, Tan A, Stanberry LR, Rosenthal SL, Milligan GN, Motamedi M, Bourne N. Benzalkonium chloride causes colposcopic changes and increased susceptibility to genital herpes infection in mice. Sexually Transmitted Diseases. 37: 579-84. PMID 20803781 DOI: 10.1097/Olq.0B013E3181Dac410 |
0.339 |
|
| 2010 |
Johnson AJ, Nelson MH, Bird MD, Chu CF, Milligan GN. Herpes simplex virus (HSV)-specific T cells activated in the absence of IFN-gamma express alternative effector functions but are not protective against genital HSV-2 infection. Journal of Reproductive Immunology. 84: 8-15. PMID 19942296 DOI: 10.1016/J.Jri.2009.09.007 |
0.742 |
|
| 2009 |
Pennock JW, Stegall R, Bubar MJ, Milligan G, Cunningham KA, Bourne N. 3,4-Methylenedioxymethamphetamine increases susceptibility to genital herpes simplex virus infection in mice. The Journal of Infectious Diseases. 200: 1247-50. PMID 19758099 DOI: 10.1086/605891 |
0.506 |
|
| 2009 |
Pennock JW, Stegall R, Bell B, Vargas G, Motamedi M, Milligan G, Bourne N. Estradiol improves genital herpes vaccine efficacy in mice. Vaccine. 27: 5830-6. PMID 19660586 DOI: 10.1016/J.Vaccine.2009.07.052 |
0.336 |
|
| 2009 |
Yoshikawa N, Yoshikawa T, Hill T, Huang C, Watts DM, Makino S, Milligan G, Chan T, Peters CJ, Tseng CT. Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2. Journal of Virology. 83: 5451-65. PMID 19297479 DOI: 10.1128/Jvi.02272-08 |
0.48 |
|
| 2008 |
Johnson AJ, Chu CF, Milligan GN. Effector CD4+ T-cell involvement in clearance of infectious herpes simplex virus type 1 from sensory ganglia and spinal cords Journal of Virology. 82: 9678-9688. PMID 18667492 DOI: 10.1128/Jvi.01159-08 |
0.549 |
|
| 2008 |
Kolli D, Bataki EL, Spetch L, Guerrero-Plata A, Jewell AM, Piedra PA, Milligan GN, Garofalo RP, Casola A. T lymphocytes contribute to antiviral immunity and pathogenesis in experimental human metapneumovirus infection Journal of Virology. 82: 8560-8569. PMID 18562525 DOI: 10.1128/Jvi.00699-08 |
0.552 |
|
| 2008 |
Chu CF, Meador MG, Young CG, Strasser JE, Bourne N, Milligan GN. Antibody-mediated protection against genital herpes simplex virus type 2 disease in mice by Fc gamma receptor-dependent and -independent mechanisms. Journal of Reproductive Immunology. 78: 58-67. PMID 17950908 DOI: 10.1016/J.Jri.2007.08.004 |
0.542 |
|
| 2007 |
Bird MD, Chu CF, Johnson AJ, Milligan GN. Early resolution of herpes simplex virus type 2 infection of the murine genital tract involves stimulation of genital parenchymal cells by gamma interferon. Journal of Virology. 81: 423-6. PMID 17065206 DOI: 10.1128/Jvi.01455-06 |
0.718 |
|
| 2005 |
Bourne N, Milligan GN, Stanberry LR, Stegall R, Pyles RB. Impact of immunization with glycoprotein D2/AS04 on herpes simplex virus type 2 shedding into the genital tract in guinea pigs that become infected. The Journal of Infectious Diseases. 192: 2117-23. PMID 16288376 DOI: 10.1086/498247 |
0.513 |
|
| 2005 |
Dobbs ME, Strasser JE, Chu CF, Chalk C, Milligan GN. Clearance of herpes simplex virus type 2 by CD8+ T cells requires gamma interferon and either perforin- or Fas-mediated cytolytic mechanisms. Journal of Virology. 79: 14546-54. PMID 16282454 DOI: 10.1128/Jvi.79.23.14546-14554.2005 |
0.592 |
|
| 2005 |
Lambert KC, Curran EM, Judy BM, Milligan GN, Lubahn DB, Estes DM. Estrogen receptor alpha (ERalpha) deficiency in macrophages results in increased stimulation of CD4+ T cells while 17beta-estradiol acts through ERalpha to increase IL-4 and GATA-3 expression in CD4+ T cells independent of antigen presentation. Journal of Immunology (Baltimore, Md. : 1950). 175: 5716-23. PMID 16237062 DOI: 10.4049/Jimmunol.175.9.5716 |
0.486 |
|
| 2005 |
Milligan GN, Meador MG, Chu CF, Young CG, Martin TL, Bourne N. Long-term presence of virus-specific plasma cells in sensory ganglia and spinal cord following intravaginal inoculation of herpes simplex virus type 2. Journal of Virology. 79: 11537-40. PMID 16103208 DOI: 10.1128/Jvi.79.17.11537-11540.2005 |
0.421 |
|
| 2005 |
Milligan GN, Young CG, Meador MG, Chu CF, Stanberry LR. Effects of candidate vaginally-applied microbicide compounds on innate immune cells. Journal of Reproductive Immunology. 66: 103-16. PMID 16040128 DOI: 10.1016/J.Jri.2005.04.003 |
0.356 |
|
| 2005 |
Carey B, DeLay M, Strasser JE, Chalk C, Dudley-McClain K, Milligan GN, Brunner HI, Thornton S, Hirsch R. A soluble divalent class I MHC/IgG1 fusion protein activates CD8+ T cells in vivo. Clinical Immunology (Orlando, Fla.). 116: 65-76. PMID 15925833 DOI: 10.1016/J.Clim.2005.02.013 |
0.471 |
|
| 2005 |
Bourne N, Stegall R, Montano R, Meador M, Stanberry LR, Milligan GN. Efficacy and toxicity of zinc salts as candidate topical microbicides against vaginal herpes simplex virus type 2 infection. Antimicrobial Agents and Chemotherapy. 49: 1181-3. PMID 15728922 DOI: 10.1128/Aac.49.3.1181-1183.2005 |
0.428 |
|
| 2004 |
Milligan GN, Chu CF, Young CG, Stanberry LR. Effect of candidate vaginally-applied microbicide compounds on recognition of antigen by CD4+ and CD8+ T lymphocytes. Biology of Reproduction. 71: 1638-45. PMID 15240422 DOI: 10.1095/Biolreprod.104.029215 |
0.451 |
|
| 2004 |
Milligan GN, Dudley-McClain KL, Young CG, Chu CF. T-cell-mediated mechanisms involved in resolution of genital herpes simplex virus type 2 (HSV-2) infection of mice. Journal of Reproductive Immunology. 61: 115-27. PMID 15063634 DOI: 10.1016/J.Jri.2003.12.002 |
0.565 |
|
| 2004 |
Milligan GN, Dudley-McClain KL, Chu CF, Young CG. Efficacy of genital T cell responses to herpes simplex virus type 2 resulting from immunization of the nasal mucosa. Virology. 318: 507-15. PMID 14972519 DOI: 10.1016/J.Virol.2003.10.010 |
0.54 |
|
| 2001 |
Milligan GN, Bourne N, Dudley KL. Role of polymorphonuclear leukocytes in resolution of HSV-2 infection of the mouse vagina. Journal of Reproductive Immunology. 49: 49-65. PMID 11137112 DOI: 10.1016/S0165-0378(00)00080-2 |
0.562 |
|
| 2000 |
Dudley KL, Bourne N, Milligan GN. Immune protection against HSV-2 in B-cell-deficient mice. Virology. 270: 454-63. PMID 10793004 DOI: 10.1006/Viro.2000.0298 |
0.563 |
|
| 1999 |
Milligan GN. Neutrophils aid in protection of the vaginal mucosae of immune mice against challenge with herpes simplex virus type 2. Journal of Virology. 73: 6380-6. PMID 10400730 DOI: 10.1128/Jvi.73.8.6380-6386.1999 |
0.611 |
|
| 1997 |
Milligan GN, Bernstein DI. Interferon-gamma enhances resolution of herpes simplex virus type 2 infection of the murine genital tract. Virology. 229: 259-68. PMID 9123869 DOI: 10.1006/Viro.1997.8441 |
0.573 |
|
| 1997 |
Bourne N, Milligan GN, Schleiss MR, Bernstein DI, Stanberry LR. DNA immunization confers protective immunity on mice challenged intravaginally with herpes simplex virus type 2. Vaccine. 14: 1230-4. PMID 8961510 DOI: 10.1016/S0264-410X(96)00027-8 |
0.54 |
|
| 1995 |
Milligan GN, Bernstein DI. Generation of humoral immune responses against herpes simplex virus type 2 in the murine female genital tract. Virology. 206: 234-41. PMID 7831778 DOI: 10.1016/S0042-6822(95)80038-7 |
0.51 |
|
| 1995 |
Milligan GN, Bernstein DI. Analysis of herpes simplex virus-specific T cells in the murine female genital tract following genital infection with herpes simplex virus type 2. Virology. 212: 481-9. PMID 7571418 DOI: 10.1006/Viro.1995.1506 |
0.607 |
|
| 1994 |
Braley-Mullen H, Milligan GN, Van Buskirk AM. Requirement for B cell-derived immunoglobulin for Th activation by the type 2 antigen polyvinylpyrrolidone. International Immunology. 6: 805-15. PMID 8086371 DOI: 10.1093/Intimm/6.6.805 |
0.463 |
|
| 1991 |
Milligan GN, Flaherty L, Braciale VL, Braciale TJ. Nonconventional (TL-encoded) major histocompatibility complex molecules present processed viral antigen to cytotoxic T lymphocytes. The Journal of Experimental Medicine. 174: 133-8. PMID 1905336 DOI: 10.1084/Jem.174.1.133 |
0.374 |
|
| 1990 |
Milligan GN, Braley-Mullen H. Production and characterization of monoclonal antibodies specific for types 6 and 19 pneumococcal capsular polysaccharides. Molecular Immunology. 26: 799-807. PMID 2601723 DOI: 10.1016/0161-5890(89)90135-1 |
0.38 |
|
| 1990 |
Milligan GN, Fairchild RL, Sterner KE, Braley-Mullen H. Type 6 and 19 pneumococcal polysaccharides coupled to erythrocytes elicit pneumococcal cell wall-specific primary IgM responses and capsular polysaccharide-specific secondary IgG responses. European Journal of Immunology. 20: 595-603. PMID 2318251 DOI: 10.1002/Eji.1830200320 |
0.381 |
|
| 1989 |
Milligan GN, Braley-Mullen H. Regulation of IgG responses by helper and suppressor T cells activated by pneumococcal capsular polysaccharides. Cellular Immunology. 119: 222-32. PMID 2465833 DOI: 10.1016/0008-8749(89)90238-4 |
0.436 |
|
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