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David W. Andrews - Publications

Affiliations: 
McMaster University, Hamilton, ON, Canada 
 University of Toronto, Toronto, ON, Canada 
Website:
http://www.dwalab.ca/

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Vervloessem T, Sasi BK, Xerxa E, Karamanou S, Kale J, La Rovere RM, Chakraborty S, Sneyers F, Vogler M, Economou A, Laurenti L, Andrews DW, Efremov DG, Bultynck G. BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models. Cell Death & Disease. 11: 769. PMID 32943617 DOI: 10.1038/S41419-020-02944-6  0.318
2020 Chi X, Nguyen D, Pemberton JM, Oesterlund EJ, Liu Q, Brahmbhatt H, Zhang Z, Lin J, Leber B, Andrews DW. The carboxyl-terminal sequence of bim enables bax activation and killing of unprimed cells. Elife. 9. PMID 31976859 DOI: 10.7554/Elife.44525  0.342
2019 Brito GC, Schormann W, Gidda SK, Mullen RT, Andrews DW. Genome-wide analysis of Homo sapiens, Arabidopsis thaliana, and Saccharomyces cerevisiae reveals novel attributes of tail-anchored membrane proteins. Bmc Genomics. 20: 835. PMID 31711414 DOI: 10.1186/S12864-019-6232-X  0.354
2019 Liu Q, Oesterlund EJ, Chi X, Pogmore J, Leber B, Andrews DW. Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2. Elife. 8. PMID 30860026 DOI: 10.7554/Elife.37689  0.33
2019 Song A, Ly M, Bar-Ad V, Werner-Wasik M, Glass J, Martinez N, Andrews D, Judy K, Evans J, Farrell C, Shi W. ACTR-49. INITIAL EXPERIENCE WITH SCALP PRESERVATION AND RADIATION PLUS CONCURRENT ALTERNATING ELECTRIC TUMOR-TREATING FIELDS (SPARE) FOR GLIOBLASTOMA PATIENTS Neuro-Oncology. 21: vi24-vi24. DOI: 10.1093/Neuonc/Noz175.091  0.302
2018 Teresinski HJ, Gidda SK, Nguyen TND, Marty Howard NJ, Porter BK, Grimberg N, Smith MD, Andrews DW, Dyer JM, Mullen RT. An RK/ST C-terminal Motif is Required for Targeting of OEP7.2 and a Subset of Other Arabidopsis Tail-Anchored Proteins to the Plastid Outer Envelope Membrane. Plant & Cell Physiology. PMID 30521026 DOI: 10.1093/Pcp/Pcy234  0.337
2017 Kale J, Osterlund EJ, Andrews DW. BCL-2 family proteins: changing partners in the dance towards death. Cell Death and Differentiation. PMID 29149100 DOI: 10.1038/Cdd.2017.186  0.309
2016 Shaked Y, Pham E, Hariharan S, Magidey K, Beyar-Katz O, Xu P, Man S, Wu F, Miller V, Andrews DW, Kerbel RS. Evidence implicating immunological host effects in the efficacy of metronomic low-dose chemotherapy. Cancer Research. PMID 27569209 DOI: 10.1158/0008-5472.Can-16-0136  0.301
2016 Pogmore JP, Pemberton JM, Chi X, Andrews DW. Using Förster-Resonance Energy Transfer to Measure Protein Interactions Between Bcl-2 Family Proteins on Mitochondrial Membranes. Methods in Molecular Biology (Clifton, N.J.). 1419: 197-212. PMID 27108441 DOI: 10.1007/978-1-4939-3581-9_15  0.352
2016 Brahmbhatt H, Uehling D, Al-Awar R, Leber B, Andrews D. Small molecules reveal an alternative mechanism of Bax activation. The Biochemical Journal. 473: 1073-83. PMID 26916338 DOI: 10.1042/Bcj20160118  0.34
2016 Thébault S, Agez M, Chi X, Stojko J, Cura V, Telerman SB, Maillet L, Gautier F, Billas-Massobrio I, Birck C, Troffer-Charlier N, Karafin T, Honoré J, Senff-Ribeiro A, Montessuit S, ... ... Andrews DW, et al. TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL. Scientific Reports. 6: 19725. PMID 26813996 DOI: 10.1038/Srep19725  0.317
2015 Brahmbhatt H, Oppermann S, Osterlund EJ, Leber B, Andrews DW. Molecular Pathways: Leveraging the BCL-2 Interactome to Kill Cancer Cells-Mitochondrial Outer Membrane Permeabilization and Beyond. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 2671-6. PMID 25838396 DOI: 10.1158/1078-0432.Ccr-14-0959  0.334
2015 Shamas-Din A, Bindner S, Chi X, Leber B, Andrews DW, Fradin C. Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax. The Biochemical Journal. 467: 495-505. PMID 25714678 DOI: 10.1042/Bj20141291  0.369
2014 Marty NJ, Teresinski HJ, Hwang YT, Clendening EA, Gidda SK, Sliwinska E, Zhang D, Miernyk JA, Brito GC, Andrews DW, Dyer JM, Mullen RT. New insights into the targeting of a subset of tail-anchored proteins to the outer mitochondrial membrane. Frontiers in Plant Science. 5: 426. PMID 25237314 DOI: 10.3389/Fpls.2014.00426  0.36
2014 Kale J, Chi X, Leber B, Andrews D. Examining the molecular mechanism of bcl-2 family proteins at membranes by fluorescence spectroscopy. Methods in Enzymology. 544: 1-23. PMID 24974284 DOI: 10.1016/B978-0-12-417158-9.00001-7  0.347
2014 Chi X, Kale J, Leber B, Andrews DW. Regulating cell death at, on, and in membranes. Biochimica Et Biophysica Acta. 1843: 2100-13. PMID 24927885 DOI: 10.1016/J.Bbamcr.2014.06.002  0.341
2014 Shamas-Din A, Satsoura D, Khan O, Zhu W, Leber B, Fradin C, Andrews DW. Multiple partners can kiss-and-run: Bax transfers between multiple membranes and permeabilizes those primed by tBid. Cell Death & Disease. 5: e1277. PMID 24901048 DOI: 10.1038/Cddis.2014.234  0.376
2014 Shivakumar S, Kurylowicz M, Hirmiz N, Manan Y, Friaa O, Shamas-Din A, Masoudian P, Leber B, Andrews DW, Fradin C. The proapoptotic protein tBid forms both superficially bound and membrane-inserted oligomers. Biophysical Journal. 106: 2085-95. PMID 24853737 DOI: 10.1016/J.Bpj.2014.03.049  0.343
2014 Ding J, Mooers BH, Zhang Z, Kale J, Falcone D, McNichol J, Huang B, Zhang XC, Xing C, Andrews DW, Lin J. After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial permeabilization. The Journal of Biological Chemistry. 289: 11873-96. PMID 24616095 DOI: 10.1074/Jbc.M114.552562  0.345
2014 Andrews DW. Abstract SY37-04: Bcl-2 family proteins as a paradigm for protein:protein interactions as chemotherapy targets Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy37-04  0.356
2013 Sarosiek KA, Chi X, Bachman JA, Sims JJ, Montero J, Patel L, Flanagan A, Andrews DW, Sorger P, Letai A. BID preferentially activates BAK while BIM preferentially activates BAX, affecting chemotherapy response. Molecular Cell. 51: 751-65. PMID 24074954 DOI: 10.1016/J.Molcel.2013.08.048  0.304
2013 Shamas-Din A, Bindner S, Zhu W, Zaltsman Y, Campbell C, Gross A, Leber B, Andrews DW, Fradin C. tBid undergoes multiple conformational changes at the membrane required for Bax activation. The Journal of Biological Chemistry. 288: 22111-27. PMID 23744079 DOI: 10.1074/Jbc.M113.482109  0.373
2013 Shamas-Din A, Kale J, Leber B, Andrews DW. Mechanisms of action of Bcl-2 family proteins. Cold Spring Harbor Perspectives in Biology. 5: a008714. PMID 23545417 DOI: 10.1101/Cshperspect.A008714  0.339
2013 Sarosiek KA, Bachman J, Montero J, Patel L, Sims JJ, Chi X, Andrews DW, Sorger P, Letai A. Abstract 1713: BAX and BAK are preferentially activated by BIM and BID, respectively, affecting clinical chemotherapy response. Cancer Research. 73: 1713-1713. DOI: 10.1158/1538-7445.Am2013-1713  0.325
2013 Shi W, Lawrence YR, Werner-Wasik M, Andrews D, Ad VB, Evans J, Moshel Y, Farrell C, Judy K, Glass J, Kim L, Dicker AP. Abstract B83: Phase I trial of panobinostat and fractionated stereotactic radiation therapy for recurrent glioma. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-B83  0.302
2013 Kurylowicz M, Shivakumar S, Shamas-Din A, Leber B, Andrews DW, Fradin C. Binding and Oligomerization of Bcl-2 Family Proteins on Supported Lipid Bilayers with Single Molecule Resolution Biophysical Journal. 104: 222a. DOI: 10.1016/J.Bpj.2012.11.1251  0.36
2012 Kale J, Liu Q, Leber B, Andrews DW. Shedding light on apoptosis at subcellular membranes. Cell. 151: 1179-84. PMID 23217705 DOI: 10.1016/J.Cell.2012.11.013  0.344
2012 Liu Q, Leber B, Andrews DW. Interactions of pro-apoptotic BH3 proteins with anti-apoptotic Bcl-2 family proteins measured in live MCF-7 cells using FLIM FRET. Cell Cycle (Georgetown, Tex.). 11: 3536-42. PMID 22895112 DOI: 10.4161/Cc.21462  0.325
2012 Aranovich A, Liu Q, Collins T, Geng F, Dixit S, Leber B, Andrews DW. Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells. Molecular Cell. 45: 754-63. PMID 22464442 DOI: 10.1016/J.Molcel.2012.01.030  0.329
2012 Satsoura D, Kučerka N, Shivakumar S, Pencer J, Griffiths C, Leber B, Andrews DW, Katsaras J, Fradin C. Interaction of the full-length Bax protein with biomimetic mitochondrial liposomes: a small-angle neutron scattering and fluorescence study. Biochimica Et Biophysica Acta. 1818: 384-401. PMID 22037145 DOI: 10.1016/J.Bbamem.2011.10.007  0.36
2012 Patel A, Shamas-Din A, Rheinstadter M, Leber B, Andrews D, Fradin C. A Supported Bilayer Model to Study the Effect of Membrane Composition on Bcl-2 Family Proteins Biophysical Journal. 102: 647a. DOI: 10.1016/J.Bpj.2011.11.3522  0.352
2012 Shamas-Din A, Bindner S, Leber B, Andrews DW, Fradin C. tBid Conformational Changes at the Membrane for the Regulation of Apoptosis Biophysical Journal. 102: 625a. DOI: 10.1016/J.Bpj.2011.11.3406  0.347
2012 Friaa O, Shivakumar S, Furukawa M, Voleti R, Shamas-Din A, Leber B, Andrews DW, Fradin C. Quantification of Protein Distribution on Liposomes using Confocal Microscopy: A Single Mobile Fluorescent Particle Detection Method Biophysical Journal. 102: 51a-52a. DOI: 10.1016/J.Bpj.2011.11.309  0.347
2011 Brito GC, Andrews DW. Removing bias against membrane proteins in interaction networks. Bmc Systems Biology. 5: 169. PMID 22011625 DOI: 10.1186/1752-0509-5-169  0.306
2011 Craney A, Tahlan K, Andrews D, Nodwell J. Bacterial transmembrane proteins that lack N-terminal signal sequences. Plos One. 6: e19421. PMID 21573234 DOI: 10.1371/Journal.Pone.0019421  0.361
2011 Falcone D, Henderson MP, Nieuwland H, Coughlan CM, Brodsky JL, Andrews DW. Stability and function of the Sec61 translocation complex depends on the Sss1p tail-anchor sequence. The Biochemical Journal. 436: 291-303. PMID 21355855 DOI: 10.1042/Bj20101865  0.313
2011 Gidda SK, Shockey JM, Falcone M, Kim PK, Rothstein SJ, Andrews DW, Dyer JM, Mullen RT. Hydrophobic-domain-dependent protein-protein interactions mediate the localization of GPAT enzymes to ER subdomains. Traffic (Copenhagen, Denmark). 12: 452-72. PMID 21214700 DOI: 10.1111/J.1600-0854.2011.01160.X  0.453
2011 Shamas-Din A, Brahmbhatt H, Leber B, Andrews DW. BH3-only proteins: Orchestrators of apoptosis. Biochimica Et Biophysica Acta. 1813: 508-20. PMID 21146563 DOI: 10.1016/J.Bbamcr.2010.11.024  0.345
2010 Leber B, Andrews DW. Closing in on the link between apoptosis and autophagy. F1000 Biology Reports. 2: 88. PMID 21283600 DOI: 10.3410/B2-88  0.307
2010 Leber B, Geng F, Kale J, Andrews DW. Drugs targeting Bcl-2 family members as an emerging strategy in cancer. Expert Reviews in Molecular Medicine. 12: e28. PMID 20822554 DOI: 10.1017/S1462399410001572  0.316
2010 Bogner C, Leber B, Andrews DW. Apoptosis: embedded in membranes. Current Opinion in Cell Biology. 22: 845-51. PMID 20801011 DOI: 10.1016/J.Ceb.2010.08.002  0.359
2010 Leber B, Lin J, Andrews DW. Still embedded together binding to membranes regulates Bcl-2 protein interactions. Oncogene. 29: 5221-30. PMID 20639903 DOI: 10.1038/Onc.2010.283  0.379
2010 Ding J, Zhang Z, Roberts GJ, Falcone M, Miao Y, Shao Y, Zhang XC, Andrews DW, Lin J. Bcl-2 and Bax interact via the BH1-3 groove-BH3 motif interface and a novel interface involving the BH4 motif. The Journal of Biological Chemistry. 285: 28749-63. PMID 20584903 DOI: 10.1074/Jbc.M110.148361  0.327
2010 Dhanoa PK, Richardson LG, Smith MD, Gidda SK, Henderson MP, Andrews DW, Mullen RT. Distinct pathways mediate the sorting of tail-anchored proteins to the plastid outer envelope. Plos One. 5: e10098. PMID 20418952 DOI: 10.1371/Journal.Pone.0010098  0.345
2010 Zhang Z, Zhu W, Lapolla SM, Miao Y, Shao Y, Falcone M, Boreham D, McFarlane N, Ding J, Johnson AE, Zhang XC, Andrews DW, Lin J. Bax forms an oligomer via separate, yet interdependent, surfaces. The Journal of Biological Chemistry. 285: 17614-27. PMID 20382739 DOI: 10.1074/Jbc.M110.113456  0.318
2010 Shamas-Din A, Bindner S, Shivakumar S, Leber B, Cecile F, Andrews DW. Effect of Different Lipid Compositions on Mitochondrial Outer Membrane Permeabilization Assisted by the Pro-Apoptotic Proteins tBID and BAX Biophysical Journal. 98: 465a. DOI: 10.1016/J.Bpj.2009.12.2528  0.339
2010 Satsoura D, Shamas-Din A, Shivakumar S, Kucerka N, Katsaras J, Leber B, Andrews DW, Fradin C. Bax Pore Formation: From Activation to Oligomerization Biophysical Journal. 98: 464a. DOI: 10.1016/J.Bpj.2009.12.2523  0.36
2009 Shamas-Din A, Bindner S, Leber B, Andrews DW, Fradin C. Binding of the Pro-Apoptotic protein Bid to Mitochondrial Membranes is a Two Step Process Biophysical Journal. 96: 425a. DOI: 10.1016/J.Bpj.2008.12.2178  0.357
2008 Billen LP, Shamas-Din A, Andrews DW. Bid: a Bax-like BH3 protein. Oncogene. 27: S93-104. PMID 19641510 DOI: 10.1038/Onc.2009.47  0.361
2008 Lovell JF, Billen LP, Bindner S, Shamas-Din A, Fradin C, Leber B, Andrews DW. Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax. Cell. 135: 1074-84. PMID 19062087 DOI: 10.1016/J.Cell.2008.11.010  0.349
2008 Billen LP, Kokoski CL, Lovell JF, Leber B, Andrews DW. Bcl-XL inhibits membrane permeabilization by competing with Bax. Plos Biology. 6: e147. PMID 18547146 DOI: 10.1371/Journal.Pbio.0060147  0.362
2008 Wang L, Kong F, Kokoski CL, Andrews DW, Xing C. Development of dimeric modulators for anti-apoptotic Bcl-2 proteins. Bioorganic & Medicinal Chemistry Letters. 18: 236-40. PMID 18023349 DOI: 10.1016/J.Bmcl.2007.10.088  0.304
2007 Leber B, Lin J, Andrews DW. Embedded together: the life and death consequences of interaction of the Bcl-2 family with membranes. Apoptosis : An International Journal On Programmed Cell Death. 12: 897-911. PMID 17453159 DOI: 10.1007/S10495-007-0746-4  0.355
2007 Henderson MP, Billen LP, Kim PK, Andrews DW. Cell-free analysis of tail-anchor protein targeting to membranes. Methods (San Diego, Calif.). 41: 427-38. PMID 17367715 DOI: 10.1016/J.Ymeth.2006.07.004  0.493
2007 Henderson MP, Hwang YT, Dyer JM, Mullen RT, Andrews DW. The C-terminus of cytochrome b5 confers endoplasmic reticulum specificity by preventing spontaneous insertion into membranes. The Biochemical Journal. 401: 701-9. PMID 16984229 DOI: 10.1042/Bj20060990  0.361
2006 Peng J, Tan C, Roberts GJ, Nikolaeva O, Zhang Z, Lapolla SM, Primorac S, Andrews DW, Lin J. tBid elicits a conformational alteration in membrane-bound Bcl-2 such that it inhibits Bax pore formation. The Journal of Biological Chemistry. 281: 35802-11. PMID 17005564 DOI: 10.1074/Jbc.M608303200  0.35
2006 Fiebig AA, Zhu W, Hollerbach C, Leber B, Andrews DW. Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line. Bmc Cancer. 6: 213. PMID 16928273 DOI: 10.1186/1471-2407-6-213  0.317
2006 Dlugosz PJ, Billen LP, Annis MG, Zhu W, Zhang Z, Lin J, Leber B, Andrews DW. Bcl-2 changes conformation to inhibit Bax oligomerization. The Embo Journal. 25: 2287-96. PMID 16642033 DOI: 10.1038/Sj.Emboj.7601126  0.334
2006 Tan C, Dlugosz PJ, Peng J, Zhang Z, Lapolla SM, Plafker SM, Andrews DW, Lin J. Auto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2. The Journal of Biological Chemistry. 281: 14764-75. PMID 16571718 DOI: 10.1074/Jbc.M602374200  0.332
2005 Annis MG, Soucie EL, Dlugosz PJ, Cruz-Aguado JA, Penn LZ, Leber B, Andrews DW. Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis. The Embo Journal. 24: 2096-103. PMID 15920484 DOI: 10.1038/Sj.Emboj.7600675  0.352
2004 Hwang YT, Pelitire SM, Henderson MP, Andrews DW, Dyer JM, Mullen RT. Novel targeting signals mediate the sorting of different isoforms of the tail-anchored membrane protein cytochrome b5 to either endoplasmic reticulum or mitochondria. The Plant Cell. 16: 3002-19. PMID 15486098 DOI: 10.1105/Tpc.104.026039  0.342
2004 Zhang Z, Lapolla SM, Annis MG, Truscott M, Roberts GJ, Miao Y, Shao Y, Tan C, Peng J, Johnson AE, Zhang XC, Andrews DW, Lin J. Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax. The Journal of Biological Chemistry. 279: 43920-8. PMID 15302859 DOI: 10.1074/Jbc.M406412200  0.309
2004 Kim PK, Annis MG, Dlugosz PJ, Leber B, Andrews DW. During apoptosis bcl-2 changes membrane topology at both the endoplasmic reticulum and mitochondria. Molecular Cell. 14: 523-9. PMID 15149601 DOI: 10.1016/S1097-2765(04)00263-1  0.49
2004 Annis MG, Yethon JA, Leber B, Andrews DW. There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum. Biochimica Et Biophysica Acta. 1644: 115-23. PMID 14996496 DOI: 10.1016/J.Bbamcr.2003.07.001  0.312
2004 McCartney AW, Dyer JM, Dhanoa PK, Kim PK, Andrews DW, McNew JA, Mullen RT. Membrane-bound fatty acid desaturases are inserted co-translationally into the ER and contain different ER retrieval motifs at their carboxy termini. The Plant Journal : For Cell and Molecular Biology. 37: 156-73. PMID 14690501 DOI: 10.1111/J.1365-313X.2004.01949.X  0.47
2003 Yethon JA, Epand RF, Leber B, Epand RM, Andrews DW. Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis. The Journal of Biological Chemistry. 278: 48935-41. PMID 14522999 DOI: 10.1074/Jbc.M306289200  0.342
2003 Legate KR, Andrews DW. The beta-subunit of the signal recognition particle receptor is a novel GTP-binding protein without intrinsic GTPase activity. The Journal of Biological Chemistry. 278: 27712-20. PMID 12759365 DOI: 10.1074/Jbc.M302158200  0.719
2002 Andrews DW. Protein origami for beginners. Developmental Cell. 3: 608-10. PMID 12431366 DOI: 10.1016/S1534-5807(02)00333-7  0.336
2001 Legate KR, Andrews DW. Assembly strategies and GTPase regulation of the eukaryotic and Escherichia coil translocons. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 79: 593-601. PMID 11716301 DOI: 10.1139/O01-140  0.73
2001 Annis MG, Zamzami N, Zhu W, Penn LZ, Kroemer G, Leber B, Andrews DW. Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event. Oncogene. 20: 1939-52. PMID 11360178 DOI: 10.1038/Sj.Onc.1204288  0.301
2001 Millman JS, Qi HY, Vulcu F, Bernstein HD, Andrews DW. FtsY binds to the Escherichia coli inner membrane via interactions with phosphatidylethanolamine and membrane proteins. The Journal of Biological Chemistry. 276: 25982-9. PMID 11353766 DOI: 10.1074/Jbc.M011331200  0.762
2000 Andrews DW. Transport across membranes: a question of navigation. Cell. 102: 139-44. PMID 10943834 DOI: 10.1016/S0092-8674(00)00019-2  0.332
2000 Legate KR, Falcone D, Andrews DW. Nucleotide-dependent binding of the GTPase domain of the signal recognition particle receptor beta-subunit to the alpha-subunit. The Journal of Biological Chemistry. 275: 27439-46. PMID 10859309 DOI: 10.1074/Jbc.M003215200  0.711
2000 Daugas E, Susin SA, Zamzami N, Ferri KF, Irinopoulou T, Larochette N, Prévost MC, Leber B, Andrews D, Penninger J, Kroemer G. Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis Faseb Journal. 14: 729-739. PMID 10744629 DOI: 10.1096/Fasebj.14.5.729  0.317
1999 Kim PK, Hollerbach C, Trimble WS, Leber B, Andrews DW. Identification of the endoplasmic reticulum targeting signal in vesicle-associated membrane proteins. The Journal of Biological Chemistry. 274: 36876-82. PMID 10601239 DOI: 10.1074/Jbc.274.52.36876  0.494
1999 Falcone D, Do H, Johnson AE, Andrews DW. Negatively charged residues in the IgM stop-transfer effector sequence regulate transmembrane polypeptide integration. The Journal of Biological Chemistry. 274: 33661-70. PMID 10559255 DOI: 10.1074/Jbc.274.47.33661  0.32
1999 Millman JS, Andrews DW. A site-specific, membrane-dependent cleavage event defines the membrane binding domain of FtsY. The Journal of Biological Chemistry. 274: 33227-34. PMID 10559196 DOI: 10.1074/Jbc.274.47.33227  0.764
1999 Thangaraju M, Sharma K, Leber B, Andrews DW, Shen SH, Srikant CB. Regulation of acidification and apoptosis by SHP-1 and Bcl-2. The Journal of Biological Chemistry. 274: 29549-57. PMID 10506221 DOI: 10.1074/Jbc.274.41.29549  0.339
1999 Lee ST, Hoeflich KP, Wasfy GW, Woodgett JR, Leber B, Andrews DW, Hedley DW, Penn LZ. Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts. Oncogene. 18: 3520-8. PMID 10376530 DOI: 10.1038/Sj.Onc.1202716  0.312
1999 Froesch BA, Aimé-Sempé C, Leber B, Andrews D, Reed JC. Inhibition of p53 transcriptional activity by Bcl-2 requires its membrane-anchoring domain Journal of Biological Chemistry. 274: 6469-6475. PMID 10037739 DOI: 10.1074/Jbc.274.10.6469  0.334
1997 Kim PK, Janiak-Spens F, Trimble WS, Leber B, Andrews DW. Evidence for multiple mechanisms for membrane binding and integration via carboxyl-terminal insertion sequences. Biochemistry. 36: 8873-82. PMID 9220974 DOI: 10.1021/Bi970090T  0.485
1997 Millman JS, Andrews DW. Switching the model: a concerted mechanism for GTPases in protein targeting. Cell. 89: 673-6. PMID 9182753 DOI: 10.1016/S0092-8674(00)80248-2  0.737
1997 Glass J, Silverman CL, Axelrod R, Corn BW, Andrews DW. Fractionated stereotactic radiotherapy with cis-platinum radiosensitization in the treatment of recurrent, progressive, or persistent malignant astrocytoma. American Journal of Clinical Oncology. 20: 226-9. PMID 9167741 DOI: 10.1097/00000421-199706000-00002  0.309
1996 Andrews DW, Johnson AE. The translocon: more than a hole in the ER membrane? Trends in Biochemical Sciences. 21: 365-9. PMID 8918188 DOI: 10.1016/S0968-0004(96)10047-5  0.341
1996 Zhu W, Cowie A, Wasfy GW, Penn LZ, Leber B, Andrews DW. Bcl-2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types. The Embo Journal. 15: 4130-41. PMID 8861942 DOI: 10.1002/J.1460-2075.1996.Tb00788.X  0.31
1996 Do H, Falcone D, Lin J, Andrews DW, Johnson AE. The cotranslational integration of membrane proteins into the phospholipid bilayer is a multistep process. Cell. 85: 369-78. PMID 8616892 DOI: 10.1016/S0092-8674(00)81115-0  0.328
1996 Young JC, Andrews DW. The signal recognition particle receptor alpha subunit assembles co-translationally on the endoplasmic reticulum membrane during an mRNA-encoded translation pause in vitro. The Embo Journal. 15: 172-81. PMID 8598200 DOI: 10.1002/J.1460-2075.1996.Tb00345.X  0.304
1995 Johnson AE, Liao S, Lin J, Hamman B, Do H, Cowie A, Andrews DW. The environment of nascent secretory and membrane proteins at the endoplasmic reticulum membrane during translocation and integration. Cold Spring Harbor Symposia On Quantitative Biology. 60: 71-82. PMID 8824379 DOI: 10.1101/Sqb.1995.060.01.010  0.33
1995 Young JC, Ursini J, Legate KR, Miller JD, Walter P, Andrews DW. An amino-terminal domain containing hydrophobic and hydrophilic sequences binds the signal recognition particle receptor alpha subunit to the beta subunit on the endoplasmic reticulum membrane. The Journal of Biological Chemistry. 270: 15650-7. PMID 7797564 DOI: 10.1074/Jbc.270.26.15650  0.747
1994 Janiak F, Glover JR, Leber B, Rachubinski RA, Andrews DW. Targeting of passenger protein domains to multiple intracellular membranes. The Biochemical Journal. 300: 191-9. PMID 8198533 DOI: 10.1042/Bj3000191  0.314
1994 Czarnota GJ, Andrews DW, Farrow NA, Ottensmeyer FP. A structure for the signal sequence binding protein SRP54: 3D reconstruction from STEM images of single molecules. Journal of Structural Biology. 113: 35-46. PMID 7880651 DOI: 10.1006/Jsbi.1994.1030  0.317
1991 Thrift RN, Andrews DW, Walter P, Johnson AE. A nascent membrane protein is located adjacent to ER membrane proteins throughout its integration and translation. The Journal of Cell Biology. 112: 809-21. PMID 1999459 DOI: 10.1083/Jcb.112.5.809  0.506
1989 Andrews DW, Lauffer L, Walter P, Lingappa VR. Evidence for a two-step mechanism involved in assembly of functional signal recognition particle receptor. The Journal of Cell Biology. 108: 797-810. PMID 2537835 DOI: 10.1083/Jcb.108.3.797  0.507
1987 Andrews DW, Walter P, Ottensmeyer FP. Evidence for an extended 7SL RNA structure in the signal recognition particle. The Embo Journal. 6: 3471-7. PMID 2828031 DOI: 10.1002/J.1460-2075.1987.Tb02671.X  0.434
1986 Mize NK, Andrews DW, Lingappa VR. A stop transfer sequence recognizes receptors for nascent chain translocation across the endoplasmic reticulum membrane. Cell. 47: 711-9. PMID 3096576 DOI: 10.1016/0092-8674(86)90514-3  0.326
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