Timothy H. Bestor - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
Genetics, Biochemistry, Molecular Biology

108 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Boulard M, Rucli S, Edwards JR, Bestor TH. Methylation-directed glycosylation of chromatin factors represses retrotransposon promoters. Proceedings of the National Academy of Sciences of the United States of America. PMID 32522876 DOI: 10.1073/Pnas.1912074117  0.583
2018 Yarychkivska O, Shahabuddin Z, Comfort N, Boulard M, Bestor TH. BAH domains and a histone-like motif in DNA methyltransferase 1 (DNMT1) regulate de novo and maintenance methylation in vivo. The Journal of Biological Chemistry. PMID 30341171 DOI: 10.1074/Jbc.Ra118.004612  0.563
2018 Li X, Erturk E, Chen X, Kumar S, Guo C, Jockusch S, Russo JJ, Bestor TH, Ju J. Photochemical conversion of a cytidine derivative to a thymidine analog via [2+2]-cycloaddition. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. PMID 29926889 DOI: 10.1039/C8Pp00161H  0.526
2018 Yarychkivska O, Tavana O, Gu W, Bestor TH. Independent functions of DNMT1 and USP7 at replication foci. Epigenetics & Chromatin. 11: 9. PMID 29482658 DOI: 10.1186/S13072-018-0179-Z  0.382
2017 Edwards JR, Yarychkivska O, Boulard M, Bestor TH. DNA methylation and DNA methyltransferases. Epigenetics & Chromatin. 10: 23. PMID 28503201 DOI: 10.1186/S13072-017-0130-8  0.568
2016 Boulard M, Edwards JR, Bestor TH. Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10. Epigenetics & Chromatin. 9: 22. PMID 27252784 DOI: 10.1186/S13072-016-0069-1  0.359
2015 Boulard M, Edwards JR, Bestor TH. FBXL10 protects Polycomb-bound genes from hypermethylation. Nature Genetics. 47: 479-85. PMID 25848754 DOI: 10.1038/Ng.3272  0.461
2015 Bestor TH, Edwards JR, Boulard M. Reply to Wilkinson: Minor role of programmed methylation and demethylation in mammalian development. Proceedings of the National Academy of Sciences of the United States of America. 112: E2117. PMID 25848064 DOI: 10.1073/Pnas.1504199112  0.474
2015 Bestor TH, Edwards JR, Boulard M. Notes on the role of dynamic DNA methylation in mammalian development. Proceedings of the National Academy of Sciences of the United States of America. 112: 6796-9. PMID 25368180 DOI: 10.1073/Pnas.1415301111  0.584
2014 O'Donnell AH, Edwards JR, Rollins RA, Vander Kraats ND, Su T, Hibshoosh HH, Bestor TH. Methylation Abnormalities in Mammary Carcinoma: The Methylation Suicide Hypothesis. Journal of Cancer Therapy. 5: 1311-1324. PMID 25960928 DOI: 10.4236/Jct.2014.514131  0.503
2014 Kao TH, Liao HF, Wolf D, Tai KY, Chuang CY, Lee HS, Kuo HC, Hata K, Zhang X, Cheng X, Goff SP, Ooi SK, Bestor TH, Lin SP. Ectopic DNMT3L triggers assembly of a repressive complex for retroviral silencing in somatic cells. Journal of Virology. 88: 10680-95. PMID 24991018 DOI: 10.1128/Jvi.01176-14  0.565
2012 Stadtfeld M, Apostolou E, Ferrari F, Choi J, Walsh RM, Chen T, Ooi SS, Kim SY, Bestor TH, Shioda T, Park PJ, Hochedlinger K. Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nature Genetics. 44: 398-405, S1-2. PMID 22387999 DOI: 10.1038/Ng.1110  0.356
2011 Song J, Rechkoblit O, Bestor TH, Patel DJ. Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science (New York, N.Y.). 331: 1036-40. PMID 21163962 DOI: 10.1126/Science.1195380  0.568
2010 Schulz R, Proudhon C, Bestor TH, Woodfine K, Lin CS, Lin SP, Prissette M, Oakey RJ, Bourc'his D. The parental non-equivalence of imprinting control regions during mammalian development and evolution. Plos Genetics. 6: e1001214. PMID 21124941 DOI: 10.1371/Journal.Pgen.1001214  0.445
2010 Ooi SK, Wolf D, Hartung O, Agarwal S, Daley GQ, Goff SP, Bestor TH. Dynamic instability of genomic methylation patterns in pluripotent stem cells. Epigenetics & Chromatin. 3: 17. PMID 20868487 DOI: 10.1186/1756-8935-3-17  0.528
2010 Edwards JR, O'Donnell AH, Rollins RA, Peckham HE, Lee C, Milekic MH, Chanrion B, Fu Y, Su T, Hibshoosh H, Gingrich JA, Haghighi F, Nutter R, Bestor TH. Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns. Genome Research. 20: 972-80. PMID 20488932 DOI: 10.1101/Gr.101535.109  0.566
2009 Ooi SK, O'Donnell AH, Bestor TH. Mammalian cytosine methylation at a glance. Journal of Cell Science. 122: 2787-91. PMID 19657014 DOI: 10.1242/Jcs.015123  0.541
2009 Xu X, Gammon MD, Zhang Y, Bestor TH, Zeisel SH, Wetmur JG, Wallenstein S, Bradshaw PT, Garbowski G, Teitelbaum SL, Neugut AI, Santella RM, Chen J. BRCA1 promoter methylation is associated with increased mortality among women with breast cancer. Breast Cancer Research and Treatment. 115: 397-404. PMID 18521744 DOI: 10.1007/S10549-008-0075-5  0.352
2008 Aravin AA, Sachidanandam R, Bourc'his D, Schaefer C, Pezic D, Toth KF, Bestor T, Hannon GJ. A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Molecular Cell. 31: 785-99. PMID 18922463 DOI: 10.1016/J.Molcel.2008.09.003  0.569
2008 Mahadevaiah SK, Bourc'his D, de Rooij DG, Bestor TH, Turner JM, Burgoyne PS. Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation. The Journal of Cell Biology. 182: 263-76. PMID 18663141 DOI: 10.1083/Jcb.200710195  0.319
2008 Ooi SK, Bestor TH. The colorful history of active DNA demethylation. Cell. 133: 1145-8. PMID 18585349 DOI: 10.1016/J.Cell.2008.06.009  0.477
2008 Schulz R, Woodfine K, Menheniott TR, Bourc'his D, Bestor T, Oakey RJ. WAMIDEX: a web atlas of murine genomic imprinting and differential expression. Epigenetics. 3: 89-96. PMID 18398312 DOI: 10.4161/Epi.3.2.5900  0.358
2008 Ooi SK, Bestor TH. Cytosine methylation: remaining faithful. Current Biology : Cb. 18: R174-6. PMID 18302924 DOI: 10.1016/J.Cub.2007.12.045  0.573
2008 Bestor TH. Regulation of de novo methylation in mammals Gbm Annual Spring Meeting Mosbach 2008. 2008. DOI: 10.1240/SAV_GBM_2008_M_002240  0.407
2007 Wood AJ, Bourc'his D, Bestor TH, Oakey RJ. Allele-specific demethylation at an imprinted mammalian promoter. Nucleic Acids Research. 35: 7031-9. PMID 17942418 DOI: 10.1093/nar/gkm742  0.398
2007 La Salle S, Oakes CC, Neaga OR, Bourc'his D, Bestor TH, Trasler JM. Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L. Bmc Developmental Biology. 7: 104. PMID 17875220 DOI: 10.1186/1471-213X-7-104  0.55
2007 Ooi SK, Qiu C, Bernstein E, Li K, Jia D, Yang Z, Erdjument-Bromage H, Tempst P, Lin SP, Allis CD, Cheng X, Bestor TH. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature. 448: 714-7. PMID 17687327 DOI: 10.1038/Nature05987  0.532
2007 Schaefer CB, Ooi SK, Bestor TH, Bourc'his D. Epigenetic decisions in mammalian germ cells. Science (New York, N.Y.). 316: 398-9. PMID 17446388 DOI: 10.1126/Science.1137544  0.553
2007 Lucifero D, La Salle S, Bourc'his D, Martel J, Bestor TH, Trasler JM. Coordinate regulation of DNA methyltransferase expression during oogenesis. Bmc Developmental Biology. 7: 36. PMID 17445268 DOI: 10.1186/1471-213X-7-36  0.557
2007 Carmell MA, Girard A, van de Kant HJG, Bourc'his D, Bestor TH, de Rooij DG, Hannon GJ. MIWI2 Is Essential for Spermatogenesis and Repression of Transposons in the Mouse Male Germline Developmental Cell. 12: 503-514. PMID 17395546 DOI: 10.1016/J.Devcel.2007.03.001  0.363
2007 Tanay A, O'Donnell AH, Damelin M, Bestor TH. Hyperconserved CpG domains underlie Polycomb-binding sites. Proceedings of the National Academy of Sciences of the United States of America. 104: 5521-6. PMID 17376869 DOI: 10.1073/Pnas.0609746104  0.472
2007 Damelin M, Bestor TH. Biological functions of DNA methyltransferase 1 require its methyltransferase activity. Molecular and Cellular Biology. 27: 3891-9. PMID 17371843 DOI: 10.1128/Mcb.00036-07  0.558
2007 Bestor TH, Goll MG. Specific Methylation of tRNAAsp by a DNA Methyltransferase Homologue The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A206-A  0.77
2006 Shovlin TC, Bourc'his D, La Salle S, O'Doherty A, Trasler JM, Bestor TH, Walsh CP. Sex-specific promoters regulate Dnmt3L expression in mouse germ cells. Human Reproduction (Oxford, England). 22: 457-67. PMID 17060371 DOI: 10.1093/Humrep/Del379  0.514
2006 Das R, Dimitrova N, Xuan Z, Rollins RA, Haghighi F, Edwards JR, Ju J, Bestor TH, Zhang MQ. Computational prediction of methylation status in human genomic sequences. Proceedings of the National Academy of Sciences of the United States of America. 103: 10713-6. PMID 16818882 DOI: 10.1073/Pnas.0602949103  0.466
2006 Bestor TH, Bourc'his D. Genetics and epigenetics of hydatidiform moles. Nature Genetics. 38: 274-6. PMID 16501554 DOI: 10.1038/Ng0306-274  0.343
2006 Damelin M, Ooi SK, Bestor TH. Combing over heritable gene silencing. Nature Structural & Molecular Biology. 13: 100-1. PMID 16462811 DOI: 10.1038/Nsmb0206-100  0.388
2006 Goll MG, Kirpekar F, Maggert KA, Yoder JA, Hsieh CL, Zhang X, Golic KG, Jacobsen SE, Bestor TH. Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2. Science (New York, N.Y.). 311: 395-8. PMID 16424344 DOI: 10.1126/Science.1120976  0.78
2006 Rollins RA, Haghighi F, Edwards JR, Das R, Zhang MQ, Ju J, Bestor TH. Large-scale structure of genomic methylation patterns. Genome Research. 16: 157-63. PMID 16365381 DOI: 10.1101/Gr.4362006  0.505
2006 Rollins RA, Damelin M, Bestor TH. 7 Inheritance of Genomic Methylation Patterns Cold Spring Harbor Monograph Archive. 47: 141-153. DOI: 10.1101/087969766.47.141  0.611
2005 Bestor TH, Bourc'his D. Transposon silencing and imprint establishment in mammalian germ cells. Cold Spring Harbor Symposia On Quantitative Biology. 69: 381-7. PMID 16117671 DOI: 10.1101/Sqb.2004.69.381  0.355
2005 Bestor TH. Transposons reanimated in mice. Cell. 122: 322-5. PMID 16096053 DOI: 10.1016/J.Cell.2005.07.024  0.307
2005 Goll MG, Bestor TH. Eukaryotic cytosine methyltransferases. Annual Review of Biochemistry. 74: 481-514. PMID 15952895 DOI: 10.1146/Annurev.Biochem.74.010904.153721  0.781
2005 Liu J, Chen M, Deng C, Bourc'his D, Nealon JG, Erlichman B, Bestor TH, Weinstein LS. Identification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunit. Proceedings of the National Academy of Sciences of the United States of America. 102: 5513-8. PMID 15811946 DOI: 10.1073/Pnas.0408262102  0.335
2005 Bestor TH, Coxon A. Cytosine methylation: the pros and cons of DNA methylation. Current Biology : Cb. 3: 384-6. PMID 15335739 DOI: 10.1016/0960-9822(93)90209-7  0.56
2004 Bourc'his D, Bestor TH. Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature. 431: 96-9. PMID 15318244 DOI: 10.1038/Nature02886  0.548
2004 La Salle S, Mertineit C, Taketo T, Moens PB, Bestor TH, Trasler JM. Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells. Developmental Biology. 268: 403-15. PMID 15063176 DOI: 10.1016/J.Ydbio.2003.12.031  0.519
2003 Bestor TH. Imprinting errors and developmental asymmetry. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 1411-5. PMID 14511489 DOI: 10.1098/Rstb.2003.1323  0.395
2003 Bestor TH. Unanswered questions about the role of promoter methylation in carcinogenesis. Annals of the New York Academy of Sciences. 983: 22-7. PMID 12724209 DOI: 10.1111/J.1749-6632.2003.Tb05959.X  0.44
2003 Bestor TH. Cytosine methylation mediates sexual conflict. Trends in Genetics : Tig. 19: 185-90. PMID 12683970 DOI: 10.1016/S0168-9525(03)00049-0  0.395
2003 Roberts RJ, Belfort M, Bestor T, Bhagwat AS, Bickle TA, Bitinaite J, Blumenthal RM, Degtyarev SKh, Dryden DT, Dybvig K, Firman K, Gromova ES, Gumport RI, Halford SE, Hattman S, et al. A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes. Nucleic Acids Research. 31: 1805-12. PMID 12654995 DOI: 10.1093/Nar/Gkg274  0.405
2002 Lynch CA, Tycko B, Bestor TH, Walsh CP. Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. Molecular Cancer. 1: 2. PMID 12234381 DOI: 10.1186/1476-4598-1-2  0.449
2002 Goll MG, Bestor TH. Histone modification and replacement in chromatin activation. Genes & Development. 16: 1739-42. PMID 12130533 DOI: 10.1101/Gad.1013902  0.729
2002 Baylin S, Bestor TH. Altered methylation patterns in cancer cell genomes: cause or consequence? Cancer Cell. 1: 299-305. PMID 12086841 DOI: 10.1016/S1535-6108(02)00061-2  0.518
2002 Weksberg R, Shuman C, Caluseriu O, Smith AC, Fei YL, Nishikawa J, Stockley TL, Best L, Chitayat D, Olney A, Ives E, Schneider A, Bestor TH, Li M, Sadowski P, et al. Discordant KCNQ1OT1 imprinting in sets of monozygotic twins discordant for Beckwith-Wiedemann syndrome. Human Molecular Genetics. 11: 1317-25. PMID 12019213 DOI: 10.1093/Hmg/11.11.1317  0.379
2002 Ratnam S, Mertineit C, Ding F, Howell CY, Clarke HJ, Bestor TH, Chaillet JR, Trasler JM. Dynamics of Dnmt1 methyltransferase expression and intracellular localization during oogenesis and preimplantation development. Developmental Biology. 245: 304-14. PMID 11977983 DOI: 10.1006/Dbio.2002.0628  0.52
2002 Bourc'his D, Bestor TH. Helicase homologues maintain cytosine methylation in plants and mammals. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 24: 297-9. PMID 11948614 DOI: 10.1002/Bies.10078  0.508
2002 Lucifero D, Mertineit C, Clarke HJ, Bestor TH, Trasler JM. Methylation dynamics of imprinted genes in mouse germ cells. Genomics. 79: 530-8. PMID 11944985 DOI: 10.1006/Geno.2002.6732  0.545
2001 Bourc'his D, Xu GL, Lin CS, Bollman B, Bestor TH. Dnmt3L and the establishment of maternal genomic imprints. Science (New York, N.Y.). 294: 2536-9. PMID 11719692 DOI: 10.1126/Science.1065848  0.567
2001 Howell CY, Bestor TH, Ding F, Latham KE, Mertineit C, Trasler JM, Chaillet JR. Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene. Cell. 104: 829-38. PMID 11290321 DOI: 10.1016/S0092-8674(01)00280-X  0.547
2001 Dong A, Yoder JA, Zhang X, Zhou L, Bestor TH, Cheng X. Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA Nucleic Acids Research. 29: 439-448. PMID 11139614 DOI: 10.1093/Nar/29.2.439  0.452
2000 Bestor TH. The DNA methyltransferases of mammals. Human Molecular Genetics. 9: 2395-402. PMID 11005794 DOI: 10.1093/Hmg/9.16.2395  0.566
2000 Warnecke PM, Bestor TH. Cytosine methylation and human cancer. Current Opinion in Oncology. 12: 68-73. PMID 10687732 DOI: 10.1097/00001622-200001000-00012  0.435
2000 Bestor TH. Gene silencing as a threat to the success of gene therapy. The Journal of Clinical Investigation. 105: 409-11. PMID 10683368 DOI: 10.1172/Jci9459  0.482
2000 Xu GL, Bestor TH, Bourc'his D, Hsieh CL, Tommerup N, Bugge M, Hulten M, Qu X, Russo JJ, Viegas-Péquignot E. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature. 402: 187-91. PMID 10647011 DOI: 10.1038/46052  0.464
2000 Bestor TH. Sex brings transposons and genomes into conflict. Genetica. 107: 289-295. DOI: 10.1007/978-94-011-4156-7_28  0.375
1999 Dao D, Walsh CP, Yuan L, Gorelov D, Feng L, Hensle T, Nisen P, Yamashiro DJ, Bestor TH, Tycko B. Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting. Human Molecular Genetics. 8: 1337-52. PMID 10369881 DOI: 10.1093/Hmg/8.7.1337  0.435
1999 Walsh CP, Bestor TH. Cytosine methylation and mammalian development. Genes & Development. 13: 26-34. PMID 9887097 DOI: 10.1101/Gad.13.1.26  0.516
1998 Walsh CP, Chaillet JR, Bestor TH. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nature Genetics. 20: 116-7. PMID 9771701 DOI: 10.1038/2413  0.499
1998 Bestor TH. Gene silencing. Methylation meets acetylation. Nature. 393: 311-2. PMID 9620794 DOI: 10.1038/30613  0.565
1998 Bestor TH. The host defence function of genomic methylation patterns. Novartis Foundation Symposium. 214: 187-95; discussion 1. PMID 9601018 DOI: 10.1002/9780470515501.Ch11  0.512
1998 Bestor TH. Cytosine methylation and the unequal developmental potentials of the oocyte and sperm genomes. American Journal of Human Genetics. 62: 1269-73. PMID 9585619 DOI: 10.1086/301891  0.4
1998 Yoder JA, Bestor TH. A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast. Human Molecular Genetics. 7: 279-84. PMID 9425235 DOI: 10.1093/Hmg/7.2.279  0.531
1997 Xu GL, Bestor TH. Cytosine methylation targetted to pre-determined sequences. Nature Genetics. 17: 376-8. PMID 9398832 DOI: 10.1038/Ng1297-376  0.433
1997 Yoder JA, Walsh CP, Bestor TH. Cytosine methylation and the ecology of intragenomic parasites. Trends in Genetics : Tig. 13: 335-40. PMID 9260521 DOI: 10.1016/S0168-9525(97)01181-5  0.546
1997 Yoder JA, Soman NS, Verdine GL, Bestor TH. DNA (cytosine-5)-methyltransferases in mouse cells and tissues. Studies with a mechanism-based probe. Journal of Molecular Biology. 270: 385-95. PMID 9237905 DOI: 10.1006/Jmbi.1997.1125  0.582
1997 Turker MS, Bestor TH. Formation of methylation patterns in the mammalian genome. Mutation Research. 386: 119-30. PMID 9113113 DOI: 10.1016/S1383-5742(96)00048-8  0.581
1997 Frostesjö L, Holm I, Grahn B, Page AW, Bestor TH, Heby O. Interference with DNA methyltransferase activity and genome methylation during F9 teratocarcinoma stem cell differentiation induced by polyamine depletion. The Journal of Biological Chemistry. 272: 4359-66. PMID 9020157 DOI: 10.1074/Jbc.272.7.4359  0.526
1997 Yoder JA, Yen RW, Vertino PM, Bestor TH, Baylin SB. New 5' regions of the murine and human genes for DNA (cytosine-5)-methyltransferase. The Journal of Biological Chemistry. 271: 31092-7. PMID 8940105 DOI: 10.1074/Jbc.271.49.31092  0.547
1997 Trasler JM, Trasler DG, Bestor TH, Li E, Ghibu F. DNA methyltransferase in normal and Dnmtn/Dnmtn mouse embryos. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 206: 239-47. PMID 8896980 DOI: 10.1002/(Sici)1097-0177(199607)206:3<239::Aid-Aja2>3.0.Co;2-J  0.542
1997 Nelson HC, Bestor TH. Base eversion and shuffling by DNA methyltransferases. Chemistry & Biology. 3: 419-23. PMID 8807872 DOI: 10.1016/S1074-5521(96)90089-7  0.453
1997 Tycko B, Trasler J, Bestor T. Genomic imprinting: gametic mechanisms and somatic consequences. Journal of Andrology. 18: 480-486. DOI: 10.1002/J.1939-4640.1997.Tb01961.X  0.345
1996 Bestor TH, Tycko B. Creation of genomic methylation patterns. Nature Genetics. 12: 363-7. PMID 8630488 DOI: 10.1038/Ng0496-363  0.517
1995 Jue K, Bestor TH, Trasler JM. Regulated synthesis and localization of DNA methyltransferase during spermatogenesis. Biology of Reproduction. 53: 561-9. PMID 7578680 DOI: 10.1095/biolreprod53.3.561  0.495
1995 Bestor TH, Bhagwat AS, Blumenthal RM, Brooks JE, Marinus MG, Raleigh EA, Szybalski W. Preface of the proceedings to the third New England biolabs workshop on biological DNA modification Gene. 157: xi. DOI: 10.1016/0378-1119(95)90045-4  0.427
1994 Goto K, Numata M, Komura JI, Ono T, Bestor TH, Kondo H. Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice. Differentiation; Research in Biological Diversity. 56: 39-44. PMID 8026645 DOI: 10.1046/J.1432-0436.1994.56120039.X  0.449
1994 Li E, Beard C, Forster AC, Bestor TH, Jaenisch R. DNA methylation, genomic imprinting, and mammalian development. Cold Spring Harbor Symposia On Quantitative Biology. 58: 297-305. PMID 7956042 DOI: 10.1101/Sqb.1993.058.01.035  0.486
1994 Bestor TH, Verdine GL. DNA methyltransferases. Current Opinion in Cell Biology. 6: 380-9. PMID 7917329 DOI: 10.1016/0955-0674(94)90030-2  0.473
1994 Bestor TH, Chandler VL, Feinberg AP. Epigenetic effects in eukaryotic gene expression. Developmental Genetics. 15: 458-62. PMID 7834904 DOI: 10.1002/Dvg.1020150603  0.463
1993 Leonhardt H, Bestor TH. Structure, function and regulation of mammalian DNA methyltransferase. Exs. 64: 109-19. PMID 8418946 DOI: 10.1007/978-3-0348-9118-9_5  0.478
1992 Czank A, Häuselmann R, Page AW, Leonhardt H, Bestor TH, Schaffner W, Hergersberg M. Expression in mammalian cells of a cloned gene encoding murine DNA methyltransferase. Gene. 109: 259-63. PMID 1662657 DOI: 10.1016/0378-1119(91)90618-L  0.464
1992 Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell. 69: 915-26. PMID 1606615 DOI: 10.1016/0092-8674(92)90611-F  0.488
1992 Trasler JM, Alcivar AA, Hake LE, Bestor T, Hecht NB. DNA methyltransferase is developmentally expressed in replicating and non-replicating male germ cells. Nucleic Acids Research. 20: 2541-5. PMID 1598212 DOI: 10.1093/Nar/20.10.2541  0.541
1992 Leonhardt H, Page AW, Weier HU, Bestor TH. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell. 71: 865-73. PMID 1423634 DOI: 10.1016/0092-8674(92)90561-P  0.494
1992 Bestor TH, Gundersen G, Kolstø AB, Prydz H. CpG islands in mammalian gene promoters are inherently resistant to de novo methylation. Genetic Analysis, Techniques and Applications. 9: 48-53. PMID 1356381 DOI: 10.1016/1050-3862(92)90030-9  0.496
1992 Carlson LL, Page AW, Bestor TH. Properties and localization of DNA methyltransferase in preimplantation mouse embryos: Implications for genomic imprinting Genes and Development. 6: 2536-2541. PMID 1340468 DOI: 10.1101/GAD.6.12B.2536  0.41
1992 Bestor TH. Activation of mammalian DNA methyltransferase by cleavage of a Zn binding regulatory domain. The Embo Journal. 11: 2611-2617. DOI: 10.1002/J.1460-2075.1992.Tb05326.X  0.456
1990 Bestor TH. DNA methylation: evolution of a bacterial immune function into a regulator of gene expression and genome structure in higher eukaryotes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 326: 179-87. PMID 1968655 DOI: 10.1098/Rstb.1990.0002  0.579
1989 Bestor T. Structure of mammalian DNA methyltransferase as deduced from the inferred amino acid sequence and direct studies of the protein. Biochemical Society Transactions. 16: 944-7. PMID 3224759 DOI: 10.1042/Bst0160944  0.441
1988 Bestor T, Laudano A, Mattaliano R, Ingram V. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases Journal of Molecular Biology. 203: 971-983. PMID 3210246 DOI: 10.1016/0022-2836(88)90122-2  0.479
1987 Bestor T. Supercoiling-dependent sequence specificity of mammalian DNA methyltransferase. Nucleic Acids Research. 15: 3835-43. PMID 3473446 DOI: 10.1093/Nar/15.9.3835  0.463
1986 Schatten G, Bestor T, Balczon R, Henson J, Schatten H. Intracellular pH shift initiates microtubule-mediated motility during sea urchin fertilization. Annals of the New York Academy of Sciences. 466: 940-4. PMID 3460463 DOI: 10.1111/J.1749-6632.1986.Tb38480.X  0.64
1985 Bestor TH, Ingram VM. Growth-dependent expression of multiple species of DNA methyltransferase in murine erythroleukemia cells Proceedings of the National Academy of Sciences of the United States of America. 82: 2674-2678. PMID 3857609 DOI: 10.1073/Pnas.82.9.2674  0.451
1984 Bestor TH, Hellewell SB, Ingram VM. Differentiation of two mouse cell lines is associated with hypomethylation of their genomes Molecular and Cellular Biology. 4: 1800-1806. PMID 6092940  0.442
1983 Bestor TH, Ingram VM. Two DNA methyltransferases from murine erythroleukemia cells: Purification, sequence specificity, and mode of interaction with DNA Proceedings of the National Academy of Sciences of the United States of America. 80: 5559-5563. PMID 6577443 DOI: 10.1073/Pnas.80.18.5559  0.516
1982 Bestor TH, Schatten G. Configurations of microtubules in artificially activated eggs of the sea urchin Lytechinus variegatus. Experimental Cell Research. 141: 71-8. PMID 6126387 DOI: 10.1016/0014-4827(82)90069-6  0.448
1982 Schatten G, Schatten H, Bestor TH, Balczon R. Taxol inhibits the nuclear movements during fertilization and induces asters in unfertilized sea urchin eggs. The Journal of Cell Biology. 94: 455-65. PMID 6125518 DOI: 10.1083/Jcb.94.2.455  0.668
1981 Bestor TH, Schatten G. Anti-tubulin immunofluorescence microscopy of microtubules present during the pronuclear movement of sea urchin fertilization. Developmental Biology. 88: 80-91. PMID 7026323 DOI: 10.1016/0012-1606(81)90220-7  0.453
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