Michael J. Iadarola - Publications

Institution:
Duke University Medical School, Durham, NC, United States
Department:
Duke-VA Neurology Research Laboratories
Area:
pain, pain control, TRPV1

173 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Iadarola MJ, Sapio MR, Loydpierson AJ, Mervis CB, Fehrenbacher JC, Vasko MR, Maric D, Eisenberg DP, Nash TA, Kippenhan JS, Garvey MH, Mannes AJ, Gregory MD, Berman KF. Syntaxin1A overexpression and pain insensitivity in individuals with 7q11.23 duplication syndrome. Jci Insight. PMID 38261410 DOI: 10.1172/jci.insight.176147  0.801
2023 Sapio MR, King DM, Staedtler ES, Maric D, Jahanipour J, Kurochkina NA, Manalo AP, Ghetti A, Mannes AJ, Iadarola MJ. Expression pattern analysis and characterization of the hereditary sensory and autonomic neuropathy 2 A (HSAN2A) gene with no lysine kinase (WNK1) in human dorsal root ganglion. Experimental Neurology. 370: 114552. PMID 37793538 DOI: 10.1016/j.expneurol.2023.114552  0.785
2023 Kurochkina N, Sapio MR, Iadarola MJ, Hall BE, Kulkarni AB. Multiprotein Assemblies, Phosphorylation and Dephosphorylation in Neuronal Cytoskeleton. Biorxiv : the Preprint Server For Biology. PMID 37502949 DOI: 10.1101/2023.06.21.545989  0.643
2023 Grant PE, Caneris OA, Gonzalez RG, Iadarola MJ, Sapio MR, Mannes AJ, Borsook D. Analgesia after Dorsal Root Ganglionic injection under CT-guidance in a patient with intractable phantom limb pain. Pain Medicine (Malden, Mass.). PMID 36975616 DOI: 10.1093/pm/pnad039  0.781
2022 Ma W, Sapio MR, Manalo AP, Maric D, Dougherty MK, Goto T, Mannes AJ, Iadarola MJ. Anatomical Analysis of Transient Potential Vanilloid Receptor 1 (+) and Mu-Opioid Receptor (+) Co-expression in Rat Dorsal Root Ganglion Neurons. Frontiers in Molecular Neuroscience. 15: 926596. PMID 35875671 DOI: 10.3389/fnmol.2022.926596  0.797
2022 Kim JJ, Sapio MR, Vazquez FA, Maric D, Loydpierson AJ, Ma W, Zarate CA, Iadarola MJ, Mannes AJ. Transcriptional Activation, Deactivation and Rebound Patterns in Cortex, Hippocampus and Amygdala in Response to Ketamine Infusion in Rats. Frontiers in Molecular Neuroscience. 15: 892345. PMID 35706427 DOI: 10.3389/fnmol.2022.892345  0.77
2022 Iadarola MJ, Sapio MR, Mannes AJ. Be in it for the long haul: a commentary on human tissue recovery initiatives. The Journal of Pain. PMID 35504570 DOI: 10.1016/j.jpain.2022.04.009  0.778
2022 Hall BE, Macdonald E, Cassidy M, Yun S, Sapio MR, Ray P, Doty M, Nara P, Burton MD, Shiers S, Ray-Chaudhury A, Mannes AJ, Price TJ, Iadarola MJ, Kulkarni AB. Transcriptomic analysis of human sensory neurons in painful diabetic neuropathy reveals inflammation and neuronal loss. Scientific Reports. 12: 4729. PMID 35304484 DOI: 10.1038/s41598-022-08100-8  0.796
2021 Goto T, Sapio MR, Maric D, Robinson JM, Domenichiello AF, Saligan LN, Mannes AJ, Iadarola MJ. Longitudinal peripheral tissue RNA-Seq transcriptomic profiling, hyperalgesia, and wound healing in the rat plantar surgical incision model. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21852. PMID 34499774 DOI: 10.1096/fj.202100347R  0.776
2021 Iadarola MJ, Brown DC, Nahama A, Sapio MR, Mannes AJ. Pain Treatment in the Companion Canine Model to Validate Rodent Results and Incentivize the Transition to Human Clinical Trials. Frontiers in Pharmacology. 12: 705743. PMID 34421597 DOI: 10.3389/fphar.2021.705743  0.785
2021 Sapio MR, Kim JJ, Loydpierson AJ, Maric D, Goto T, Vazquez FA, Dougherty MK, Narasimhan R, Muhly WT, Iadarola MJ, Mannes AJ. The persistent pain transcriptome: identification of cells and molecules activated by hyperalgesia. The Journal of Pain. PMID 33892151 DOI: 10.1016/j.jpain.2021.03.155  0.81
2020 Sapio MR, Vazquez FA, Loydpierson AJ, Maric D, Kim JJ, LaPaglia DM, Puhl HL, Lu VB, Ikeda SR, Mannes AJ, Iadarola MJ. Comparative Analysis of Dorsal Root, Nodose and Sympathetic Ganglia for the Development of New Analgesics. Frontiers in Neuroscience. 14: 615362. PMID 33424545 DOI: 10.3389/fnins.2020.615362  0.804
2020 Goto T, Sapio MR, Maric D, Robinson JM, Saligan LN, Mannes AJ, Iadarola MJ. Longitudinal transcriptomic profiling in carrageenan-induced rat hind paw peripheral inflammation and hyperalgesia reveals progressive recruitment of innate immune system components. The Journal of Pain : Official Journal of the American Pain Society. PMID 33227508 DOI: 10.1016/j.jpain.2020.11.001  0.792
2020 Rosenstein RK, Pastrana DV, Starrett GJ, Sapio MR, Hill NT, Jo JH, Lee CR, Iadarola MJ, Buck CB, Kong HH, Brownell I, Cowen EW. Host-Pathogen Interactions in Human Polyomavirus 7 (HPyV7)-associated Pruritic Skin Eruption. The Journal of Investigative Dermatology. PMID 33075349 DOI: 10.1016/j.jid.2020.09.014  0.618
2020 Domenichiello AF, Sapio MR, Loydpierson AJ, Maric D, Goto T, Horowitz MS, Keyes GS, Yuan ZX, Majchrzak-Hong SF, Mannes AJ, Iadarola MJ, Ramsden CE. Molecular pathways linking oxylipins to nociception in rats. The Journal of Pain : Official Journal of the American Pain Society. PMID 33031942 DOI: 10.1016/j.jpain.2020.09.001  0.792
2020 Wang XM, Gu P, Saligan L, Iadarola M, Ti LK, Wong S, Cheung CW. Dysregulation of EAAT2 and VGLUT2 spinal glutamate transports via histone deacetylase 2 (HDAC2) contributes to paclitaxel-induced painful neuropathy. Molecular Cancer Therapeutics. PMID 32847971 DOI: 10.1158/1535-7163.MCT-20-0006  0.4
2020 Davis KD, Aghaeepour N, Ahn AH, Angst MS, Borsook D, Brenton A, Burczynski ME, Crean C, Edwards R, Gaudilliere B, Hergenroeder GW, Iadarola MJ, Iyengar S, Jiang Y, Kong JT, et al. Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities. Nature Reviews. Neurology. PMID 32541893 DOI: 10.1038/S41582-020-0362-2  0.385
2020 Sapio MR, Iadarola MJ, Loydpierson AJ, Kim JJ, Thierry-Mieg D, Thierry-Mieg J, Maric D, Mannes AJ. Dynorphin and Enkephalin Opioid Peptides and Transcripts in Spinal Cord and Dorsal Root Ganglion During Peripheral Inflammatory Hyperalgesia and Allodynia. The Journal of Pain : Official Journal of the American Pain Society. PMID 31931229 DOI: 10.1016/J.Jpain.2020.01.001  0.801
2019 Harrison BJ, Park JW, Gomes C, Petruska JC, Sapio MR, Iadarola MJ, Chariker JH, Rouchka EC. Detection of Differentially Expressed Cleavage Site Intervals Within 3' Untranslated Regions Using CSI-UTR Reveals Regulated Interaction Motifs. Frontiers in Genetics. 10: 182. PMID 30915105 DOI: 10.3389/Fgene.2019.00182  0.685
2019 Sapio MR, Iadarola MJ, LaPaglia DM, Lehky T, Thurm AE, Danley KM, Fuhr SR, Lee MD, Huey AE, Sharp SJ, Tsao JW, Yanovski JA, Mannes AJ, Han JC. Haploinsufficiency of the brain-derived neurotrophic factor (BDNF) gene is associated with reduced pain sensitivity. Pain. PMID 30855519 DOI: 10.1097/J.Pain.0000000000001485  0.804
2019 Sapio M, Iadarola M, Loydpierson A, Kim J, Mannes A. (350) The Persistent Pain Transcriptome: Distinct Transcriptional Signatures of Post-Surgical and Inflammatory Models Define Convergent Pathways to the Transition to Hyperalgesia The Journal of Pain. 20: S62. DOI: 10.1016/J.Jpain.2019.02.046  0.816
2019 Kim J, Sapio M, Loydpierson A, Mannes A, Iadarola M. (342) Molecular Transcriptomic Effects of General Anesthesia on Gene Expression in Frontal Lobe, Hippocampus, and Amygdala after Administration of Ketamine and Isoflurane The Journal of Pain. 20: S60. DOI: 10.1016/J.Jpain.2019.02.038  0.784
2018 Yuan ZX, Majchrzak-Hong S, Keyes GS, Iadarola MJ, Mannes AJ, Ramsden CE. Lipidomic profiling of targeted oxylipins with ultra-performance liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry. PMID 30074088 DOI: 10.1007/S00216-018-1222-4  0.58
2018 Iadarola MJ, Sapio MR, Raithel SJ, Mannes AJ, Brown DC. Long-term pain relief in canine osteoarthritis by a single intra-articular injection of resiniferatoxin, a potent TRPV1 agonist. Pain. PMID 30015705 DOI: 10.1097/J.Pain.0000000000001314  0.801
2018 Sapio MR, Neubert JK, LaPaglia DM, Maric D, Keller JM, Raithel SJ, Rohrs EL, Anderson EM, Butman JA, Caudle RM, Brown DC, Heiss JD, Mannes AJ, Iadarola MJ. Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons. The Journal of Clinical Investigation. PMID 29408808 DOI: 10.1172/Jci94331  0.827
2018 Hall BE, Prochazkova M, Sapio MR, Minetos P, Kurochkina N, Binukumar BK, Amin ND, Terse A, Joseph J, Raithel SJ, Mannes AJ, Pant HC, Chung MK, Iadarola MJ, Kulkarni AB. Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception. Scientific Reports. 8: 1177. PMID 29352128 DOI: 10.1038/S41598-018-19532-6  0.767
2017 Raithel SJ, Sapio MR, LaPaglia DM, Iadarola MJ, Mannes AJ. Transcriptional Changes in Dorsal Spinal Cord Persist after Surgical Incision Despite Preemptive Analgesia with Peripheral Resiniferatoxin. Anesthesiology. PMID 29271803 DOI: 10.1097/Aln.0000000000002006  0.788
2017 Raithel SJ, Sapio MR, Iadarola MJ, Mannes AJ. Thermal A-δ Nociceptors, Identified by Transcriptomics, Express Higher Levels of Anesthesia-Sensitive Receptors Than Thermal C-Fibers and Are More Suppressible by Low-Dose Isoflurane. Anesthesia and Analgesia. PMID 28991117 DOI: 10.1213/Ane.0000000000002505  0.769
2017 Ramsden CE, Domenichiello AF, Yuan ZX, Sapio MR, Keyes GS, Mishra SK, Gross JR, Majchrzak-Hong S, Zamora D, Horowitz MS, Davis JM, Sorokin AV, Dey A, LaPaglia DM, Wheeler JJ, ... ... Iadarola MJ, et al. A systems approach for discovering linoleic acid derivatives that potentially mediate pain and itch. Science Signaling. 10. PMID 28831021 DOI: 10.1126/Scisignal.Aal5241  0.81
2017 Iadarola MJ, Sapio MR, Wang X, Carrero H, Virata-Theimer ML, Sarnovsky R, Mannes AJ, FitzGerald DJ. [EXPRESS]Analgesia by Deletion of Spinal Neurokinin 1 Receptor Expressing Neurons Using a Bioengineered Substance P-Pseudomonas Exotoxin Conjugate. Molecular Pain. 13: 1744806917727657. PMID 28814145 DOI: 10.1177/1744806917727657  0.801
2017 LaPaglia DM, Sapio MR, Burbelo PD, Thierry-Mieg J, Thierry-Mieg D, Raithel SJ, Ramsden CE, Iadarola MJ, Mannes AJ. RNA-Seq investigations of human post-mortem trigeminal ganglia. Cephalalgia : An International Journal of Headache. 333102417720216. PMID 28699403 DOI: 10.1177/0333102417720216  0.785
2017 Blivis D, Haspel G, Mannes PZ, O'Donovan MJ, Iadarola MJ. Identification of a novel spinal nociceptive-motor gate control for Aδ pain stimuli in rats. Elife. 6. PMID 28537555 DOI: 10.7554/Elife.23584  0.798
2017 Blivis D, Haspel G, Mannes PZ, O'Donovan MJ, Iadarola MJ. Author response: Identification of a novel spinal nociceptive-motor gate control for Aδ pain stimuli in rats Elife. DOI: 10.7554/Elife.23584.023  0.806
2017 Sapio M, Iadarola M, Lapaglia D, Mannes A. (175) The pain transcriptome: RNA-Seq profiling of dorsal spinal cord during persistent inflammatory hyperalgesia The Journal of Pain. 18: S20. DOI: 10.1016/J.Jpain.2017.02.082  0.797
2017 Lapaglia D, Sapio M, Burbelo P, Ramsden C, Iadarola M, Mannes A. (174) RNA-Seq investigations of human post-mortem trigeminal ganglia with a perspective on headache and migraine The Journal of Pain. 18: S19-S20. DOI: 10.1016/J.Jpain.2017.02.081  0.748
2017 Raithel S, Lapaglia D, Sapio M, Iadarola M, Mannes A. (162) Pre-surgical intraplantar resiniferatoxin decreases post-operative pain in rats with plantar incision The Journal of Pain. 18: S17. DOI: 10.1016/J.Jpain.2017.02.068  0.785
2016 Salas MM, Clifford JL, Hayden JR, Iadarola MJ, Averitt DL. Local Resiniferatoxin Induces Long-Lasting Analgesia in a Rat Model of Full Thickness Thermal Injury. Pain Medicine (Malden, Mass.). PMID 27794548 DOI: 10.1093/pm/pnw260  0.412
2016 Sapio MR, Goswami SC, Gross JR, Mannes AJ, Iadarola MJ. Transcriptomic analyses of genes and tissues in inherited sensory neuropathies. Experimental Neurology. PMID 27343803 DOI: 10.1016/J.Expneurol.2016.06.023  0.778
2016 Burbelo PD, Iadarola MJ, Alevizos I, Sapio MR. Transcriptomic Segregation of Human Autoantigens Useful for the Diagnosis of Autoimmune Diseases. Molecular Diagnosis & Therapy. PMID 27259330 DOI: 10.1007/S40291-016-0211-6  0.674
2015 Bayat A, Burbelo PD, Browne SK, Quinlivan M, Martinez B, Holland SM, Buvanendran A, Kroin JS, Mannes AJ, Breuer J, Cohen JI, Iadarola MJ. Anti-cytokine autoantibodies in postherpetic neuralgia. Journal of Translational Medicine. 13: 333. PMID 26482341 DOI: 10.1186/S12967-015-0695-6  0.639
2015 Brown JD, Saeed M, Do L, Braz J, Basbaum AI, Iadarola MJ, Wilson DM, Dillon WP. CT-guided injection of a TRPV1 agonist around dorsal root ganglia decreases pain transmission in swine. Science Translational Medicine. 7: 305ra145. PMID 26378245 DOI: 10.1126/scitranslmed.aac6589  0.445
2015 Iadarola MJ, Sapio MR, Mannes AJ. A new splice of life for the μ-opioid receptor. The Journal of Clinical Investigation. 125: 2558-61. PMID 26011639 DOI: 10.1172/Jci82060  0.763
2015 Foster DC, Falsetta ML, Woeller CF, Pollock SJ, Song K, Bonham A, Haidaris CG, Stodgell CJ, Messing SP, Iadarola M, Phipps RP. Site-specific mesenchymal control of inflammatory pain to yeast challenge in vulvodynia-afflicted and pain-free women. Pain. 156: 386-96. PMID 25679469 DOI: 10.1097/01.J.Pain.0000460320.95267.5D  0.303
2015 Brown DC, Agnello K, Iadarola MJ. Intrathecal resiniferatoxin in a dog model: efficacy in bone cancer pain. Pain. 156: 1018-24. PMID 25659068 DOI: 10.1097/j.pain.0000000000000115  0.401
2015 Mannes A, Goswami S, Gross J, Gonnella G, Keller J, Kominsky H, Iadarola M. (253) Systems analyses of RNA-Seq transcriptomic responses in peripheral tissue, DRG and dorsal horn during carrageenan-induced inflammation The Journal of Pain. 16: S39. DOI: 10.1016/J.Jpain.2015.01.170  0.613
2014 Goswami SC, Mishra SK, Maric D, Kaszas K, Gonnella GL, Clokie SJ, Kominsky HD, Gross JR, Keller JM, Mannes AJ, Hoon MA, Iadarola MJ. Molecular signatures of mouse TRPV1-lineage neurons revealed by RNA-Seq transcriptome analysis. The Journal of Pain : Official Journal of the American Pain Society. 15: 1338-59. PMID 25281809 DOI: 10.1016/J.Jpain.2014.09.010  0.685
2014 Goswami SC, Thierry-Mieg D, Thierry-Mieg J, Mishra S, Hoon MA, Mannes AJ, Iadarola MJ. Itch-associated peptides: RNA-Seq and bioinformatic analysis of natriuretic precursor peptide B and gastrin releasing peptide in dorsal root and trigeminal ganglia, and the spinal cord. Molecular Pain. 10: 44. PMID 25123163 DOI: 10.1186/1744-8069-10-44  0.644
2014 Mitchell K, Lebovitz EE, Keller JM, Mannes AJ, Nemenov MI, Iadarola MJ. Nociception and inflammatory hyperalgesia evaluated in rodents using infrared laser stimulation after Trpv1 gene knockout or resiniferatoxin lesion. Pain. 155: 733-45. PMID 24434730 DOI: 10.1016/J.Pain.2014.01.007  0.629
2014 Heiss J, Iadarola M, Cantor F, Oughourli A, Smith R, Mannes A. (364) A Phase I study of the intrathecal administration of resiniferatoxin for treating severe refractory pain associated with advanced cancer The Journal of Pain. 15: S67. DOI: 10.1016/J.Jpain.2014.01.275  0.641
2013 Iadarola MJ, Gonnella GL. Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine. The Open Pain Journal. 6: 95-107. PMID 26779292 DOI: 10.2174/1876386301306010095  0.437
2013 Utreras E, Prochazkova M, Terse A, Gross J, Keller J, Iadarola MJ, Kulkarni AB. TGF-β1 sensitizes TRPV1 through Cdk5 signaling in odontoblast-like cells. Molecular Pain. 9: 24. PMID 23668392 DOI: 10.1186/1744-8069-9-24  0.366
2013 Bruehl S, Apkarian AV, Ballantyne JC, Berger A, Borsook D, Chen WG, Farrar JT, Haythornthwaite JA, Horn SD, Iadarola MJ, Inturrisi CE, Lao L, Mackey S, Mao J, Sawczuk A, et al. Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges. The Journal of Pain : Official Journal of the American Pain Society. 14: 103-13. PMID 23374939 DOI: 10.1016/J.Jpain.2012.10.016  0.367
2013 Lebovitz E, Keller J, Kaszas K, Iadarola M, Mannes A. Exploring the actions of TRPV1 positive allosteric modulators in a peripheral inflammation model The Journal of Pain. 14: S69. DOI: 10.1016/J.Jpain.2013.01.612  0.594
2012 Lebovitz EE, Keller JM, Kominsky H, Kaszas K, Maric D, Iadarola MJ. Positive allosteric modulation of TRPV1 as a novel analgesic mechanism. Molecular Pain. 8: 70. PMID 22998799 DOI: 10.1186/1744-8069-8-70  0.417
2012 Utreras E, Keller J, Terse A, Prochazkova M, Iadarola MJ, Kulkarni AB. Transforming growth factor-β1 regulates Cdk5 activity in primary sensory neurons. The Journal of Biological Chemistry. 287: 16917-29. PMID 22451679 DOI: 10.1074/jbc.M111.329979  0.39
2012 Kaszas K, Keller JM, Coddou C, Mishra SK, Hoon MA, Stojilkovic S, Jacobson KA, Iadarola MJ. Small molecule positive allosteric modulation of TRPV1 activation by vanilloids and acidic pH. The Journal of Pharmacology and Experimental Therapeutics. 340: 152-60. PMID 22005042 DOI: 10.1124/Jpet.111.183053  0.364
2011 Utreras E, Terse A, Keller J, Iadarola MJ, Kulkarni AB. Resveratrol inhibits Cdk5 activity through regulation of p35 expression. Molecular Pain. 7: 49. PMID 21736731 DOI: 10.1186/1744-8069-7-49  0.301
2011 Iadarola MJ, Mannes AJ. The vanilloid agonist resiniferatoxin for interventional-based pain control. Current Topics in Medicinal Chemistry. 11: 2171-9. PMID 21671877 DOI: 10.2174/156802611796904942  0.7
2011 Guptill V, Cui X, Khaibullina A, Keller JM, Spornick N, Mannes A, Iadarola M, Quezado ZM. Disruption of the transient receptor potential vanilloid 1 can affect survival, bacterial clearance, and cytokine gene expression during murine sepsis. Anesthesiology. 114: 1190-9. PMID 21383614 DOI: 10.1097/Aln.0B013E318212515B  0.599
2010 Mitchell K, Bates BD, Keller JM, Lopez M, Scholl L, Navarro J, Madian N, Haspel G, Nemenov MI, Iadarola MJ. Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates. Molecular Pain. 6: 94. PMID 21167052 DOI: 10.1186/1744-8069-6-94  0.313
2010 Bates BD, Mitchell K, Keller JM, Chan CC, Swaim WD, Yaskovich R, Mannes AJ, Iadarola MJ. Prolonged analgesic response of cornea to topical resiniferatoxin, a potent TRPV1 agonist. Pain. 149: 522-8. PMID 20403666 DOI: 10.1016/J.Pain.2010.03.024  0.684
2010 Mitchell K, Iadarola MJ. RT-PCR analysis of pain genes: use of gel-based RT-PCR for studying induced and tissue-enriched gene expression. Methods in Molecular Biology (Clifton, N.J.). 617: 279-95. PMID 20336429 DOI: 10.1007/978-1-60327-323-7_21  0.389
2010 Mannes A, Hughes M, Quezado Z, Berger A, Fojo T, Smith R, Butman J, Lonser R, Iadarola M. Resiniferatoxin, a potent TRPV1 agonist: Intrathecal administration to treat severe pain associated with advanced cancer—case report The Journal of Pain. 11: S43. DOI: 10.1016/J.Jpain.2010.01.181  0.667
2010 Mitchell K, Bates B, Keller J, Nemenov M, Mannes A, Iadarola M. Prolonged analgesic effect of RTX on A-delta type II fibers following peripheral administration The Journal of Pain. 11: S40. DOI: 10.1016/J.Jpain.2010.01.170  0.588
2009 Buvanendran A, Mitchell K, Kroin JS, Iadarola MJ. Cytokine gene expression after total hip arthroplasty: surgical site versus circulating neutrophil response. Anesthesia and Analgesia. 109: 959-64. PMID 19690273 DOI: 10.1213/ane.0b013e3181ac1746  0.344
2009 Utreras E, Futatsugi A, Rudrabhatla P, Keller J, Iadarola MJ, Pant HC, Kulkarni AB. Tumor necrosis factor-alpha regulates cyclin-dependent kinase 5 activity during pain signaling through transcriptional activation of p35. The Journal of Biological Chemistry. 284: 2275-84. PMID 19049962 DOI: 10.1074/Jbc.M805052200  0.308
2008 Roh EJ, Keller JM, Olah Z, Iadarola MJ, Jacobson KA. Structure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1). Bioorganic & Medicinal Chemistry. 16: 9349-58. PMID 18809334 DOI: 10.1016/J.Bmc.2008.08.048  0.343
2008 Neubert JK, Mannes AJ, Karai LJ, Jenkins AC, Zawatski L, Abu-Asab M, Iadarola MJ. Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia. Molecular Pain. 4: 3. PMID 18199335 DOI: 10.1186/1744-8069-4-3  0.689
2008 Mitchell K, Yang HY, Tessier PA, Muhly WT, Swaim WD, Szalayova I, Keller JM, Mezey E, Iadarola MJ. Localization of S100A8 and S100A9 expressing neutrophils to spinal cord during peripheral tissue inflammation. Pain. 134: 216-31. PMID 18063312 DOI: 10.1016/j.pain.2007.10.024  0.355
2008 Yang HY, Tao T, Iadarola MJ. Modulatory role of neuropeptide FF system in nociception and opiate analgesia. Neuropeptides. 42: 1-18. PMID 17854890 DOI: 10.1016/j.npep.2007.06.004  0.403
2007 Mannes AJ, Iadarola MJ. Complete pain relief: potential problems and diagnostic solutions. Nature Clinical Practice. Neurology. 3: 648-9. PMID 17984990 DOI: 10.1038/Ncpneuro0660  0.669
2007 Yang HY, Mitchell K, Keller JM, Iadarola MJ. Peripheral inflammation increases Scya2 expression in sensory ganglia and cytokine and endothelial related gene expression in inflamed tissue. Journal of Neurochemistry. 103: 1628-43. PMID 17883394 DOI: 10.1111/j.1471-4159.2007.04874.x  0.415
2007 Mannes A, Iadarola M. Potential downsides of perfect pain relief [1] Nature. 446: 24. PMID 17330023 DOI: 10.1038/446024A  0.664
2007 Khan AA, Iadarola M, Yang HY, Dionne RA. Expression of COX-1 and COX-2 in a clinical model of acute inflammation. The Journal of Pain : Official Journal of the American Pain Society. 8: 349-54. PMID 17270500 DOI: 10.1016/j.jpain.2006.10.004  0.702
2007 Pareek TK, Keller J, Kesavapany S, Agarwal N, Kuner R, Pant HC, Iadarola MJ, Brady RO, Kulkarni AB. Cyclin-dependent kinase 5 modulates nociceptive signaling through direct phosphorylation of transient receptor potential vanilloid 1. Proceedings of the National Academy of Sciences of the United States of America. 104: 660-5. PMID 17194758 DOI: 10.1073/Pnas.0609916104  0.355
2007 Nemenov M, Mitchell K, Keller J, Yaskovich R, Mannes A, Iadarola M. (627) The Journal of Pain. 8: S7. DOI: 10.1016/J.Jpain.2007.02.038  0.599
2006 Kim H, Mittal DP, Iadarola MJ, Dionne RA. Genetic predictors for acute experimental cold and heat pain sensitivity in humans. Journal of Medical Genetics. 43: e40. PMID 16882734 DOI: 10.1136/jmg.2005.036079  0.615
2006 Yang HY, Iadarola MJ. Modulatory roles of the NPFF system in pain mechanisms at the spinal level. Peptides. 27: 943-52. PMID 16443306 DOI: 10.1016/j.peptides.2005.06.030  0.451
2006 Pareek TK, Keller J, Kesavapany S, Pant HC, Iadarola MJ, Brady RO, Kulkarni AB. Cyclin-dependent kinase 5 activity regulates pain signaling. Proceedings of the National Academy of Sciences of the United States of America. 103: 791-6. PMID 16407116 DOI: 10.1073/Pnas.0510405103  0.365
2005 Brown DC, Iadarola MJ, Perkowski SZ, Erin H, Shofer F, Laszlo KJ, Olah Z, Mannes AJ. Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model. Anesthesiology. 103: 1052-9. PMID 16249680 DOI: 10.1097/00000542-200511000-00020  0.637
2005 Caudle RM, Perez FM, Del Valle-Pinero AY, Iadarola MJ. Spinal cord NR1 serine phosphorylation and NR2B subunit suppression following peripheral inflammation. Molecular Pain. 1: 25. PMID 16137337 DOI: 10.1186/1744-8069-1-25  0.626
2005 Mannes AJ, Brown DC, Keller J, Cordes L, Eckenhoff RG, Caudle RM, Iadarola MJ, Meng QC. Measurement of resiniferatoxin in serum samples by high-performance liquid chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 823: 184-8. PMID 16039169 DOI: 10.1016/J.Jchromb.2005.06.042  0.694
2005 Neubert JK, Mannes AJ, Keller J, Wexel M, Iadarola MJ, Caudle RM. Peripheral targeting of the trigeminal ganglion via the infraorbital foramen as a therapeutic strategy. Brain Research. Brain Research Protocols. 15: 119-26. PMID 16024266 DOI: 10.1016/J.Brainresprot.2005.05.003  0.752
2005 Tender GC, Walbridge S, Olah Z, Karai L, Iadarola M, Oldfield EH, Lonser RR. Selective ablation of nociceptive neurons for elimination of hyperalgesia and neurogenic inflammation Journal of Neurosurgery. 102: 522-525. PMID 15796388 DOI: 10.3171/jns.2005.102.3.0522  0.414
2004 Kim H, Neubert JK, Rowan JS, Brahim JS, Iadarola MJ, Dionne RA. Comparison of experimental and acute clinical pain responses in humans as pain phenotypes. The Journal of Pain : Official Journal of the American Pain Society. 5: 377-84. PMID 15501195 DOI: 10.1016/J.Jpain.2004.06.003  0.613
2004 Kim H, Neubert JK, San Miguel A, Xu K, Krishnaraju RK, Iadarola MJ, Goldman D, Dionne RA. Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament. Pain. 109: 488-96. PMID 15157710 DOI: 10.1016/J.Pain.2004.02.027  0.605
2004 Karai L, Brown DC, Mannes AJ, Connelly ST, Brown J, Gandal M, Wellisch OM, Neubert JK, Olah Z, Iadarola MJ. Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control. The Journal of Clinical Investigation. 113: 1344-52. PMID 15124026 DOI: 10.1172/Jci20449  0.697
2004 Kárai LJ, Russell JT, Iadarola MJ, Oláh Z. Vanilloid receptor 1 regulates multiple calcium compartments and contributes to Ca2+-induced Ca2+ release in sensory neurons. The Journal of Biological Chemistry. 279: 16377-87. PMID 14963041 DOI: 10.1074/jbc.M310891200  0.312
2004 Becerra L, Iadarola M, Borsook D. CNS Activation by Noxious Heat to the Hand or Foot: Site-Dependent Delay in Sensory but Not Emotion Circuitry Journal of Neurophysiology. 91: 533-541. PMID 14715722 DOI: 10.1152/Jn.00326.2003  0.305
2004 Tender GC, Walbridge S, Olah Z, Karai L, Iadarola M, Oldfield EH, Lonser RR. 740 Selective Ablation of Nociceptive Neurons for Elimination of Neuropathic Pain Neurosurgery. 55: 465-466. DOI: 10.1097/00006123-200408000-00076  0.406
2004 Mannes A, Karai L, Muhly W, Neubert J, Keller J, Iadarola M, Caudle R. Joint, muscle, and visceral pain The Journal of Pain. 5: S24. DOI: 10.1016/J.Jpain.2004.02.062  0.631
2003 Caudle RM, Karai L, Mena N, Cooper BY, Mannes AJ, Perez FM, Iadarola MJ, Olah Z. Resiniferatoxin-induced loss of plasma membrane in vanilloid receptor expressing cells. Neurotoxicology. 24: 895-908. PMID 14637384 DOI: 10.1016/S0161-813X(03)00146-3  0.713
2003 Neubert JK, Karai L, Jun JH, Kim HS, Olah Z, Iadarola MJ. Peripherally induced resiniferatoxin analgesia. Pain. 104: 219-28. PMID 12855332 DOI: 10.1016/S0304-3959(03)00009-5  0.428
2003 Sarntinoranont M, Iadarola MJ, Lonser RR, Morrison PF. Direct interstitial infusion of NK1-targeted neurotoxin into the spinal cord: a computational model. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 285: R243-54. PMID 12793999 DOI: 10.1152/Ajpregu.00472.2002  0.368
2003 Yang HY, Iadarola MJ. Activation of spinal neuropeptide FF and the neuropeptide FF receptor 2 during inflammatory hyperalgesia in rats. Neuroscience. 118: 179-87. PMID 12676148 DOI: 10.1016/S0306-4522(02)00931-4  0.303
2003 Mannes AJ, Martin BM, Yang HY, Keller JM, Lewin S, Gaiser RR, Iadarola MJ. Cystatin C as a cerebrospinal fluid biomarker for pain in humans. Pain. 102: 251-6. PMID 12670666 DOI: 10.1016/S0304-3959(02)00403-7  0.681
2003 Kim H, Neubert JK, Iadarola MJ, Goldman D, Dionne RA. Evaluation of single nucleotide polymorphisms in genes related to the vanilloid receptor and cyclooxygenase-2 in human pain sensitivity. Clinical Pharmacology & Therapeutics. 73: P98-P98. DOI: 10.1016/S0009-9236(03)90716-8  0.592
2003 Neubert J, Mannes A, Karai L, Iadarola M, Dionne R. Percutaneous Resiniferatoxin-Induced Incisional Pain Analgesia Clinical Pharmacology & Therapeutics. 73: P30-P30. DOI: 10.1016/S0009-9236(03)90464-4  0.613
2002 Mannes AJ, Cimino Brown D, Perkowski SZ, Keller J, Caudle RM, Iadarola MJ, Meng QC. Measurement of resiniferatoxin in cerebrospinal fluid by high-performance liquid chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 780: 475-9. PMID 12401376 DOI: 10.1016/S1570-0232(02)00626-8  0.698
2002 Rosier EM, Iadarola MJ, Coghill RC. Reproducibility of pain measurement and pain perception. Pain. 98: 205-16. PMID 12098633 DOI: 10.1016/S0304-3959(02)00048-9  0.625
2002 Olah Z, Karai L, Iadarola MJ. Protein kinase C(alpha) is required for vanilloid receptor 1 activation. Evidence for multiple signaling pathways. The Journal of Biological Chemistry. 277: 35752-9. PMID 12095983 DOI: 10.1074/jbc.M201551200  0.333
2001 Caudle RM, Mannes AJ, Benoliel R, Eliav E, Iadarola MJ. Intrathecally administered cholera toxin blocks allodynia and hyperalgesia in persistent pain models. The Journal of Pain : Official Journal of the American Pain Society. 2: 118-27. PMID 14622833 DOI: 10.1054/Jpai.2000.19948  0.776
2001 Coghill RC, Gilron I, Iadarola MJ. Hemispheric lateralization of somatosensory processing. Journal of Neurophysiology. 85: 2602-12. PMID 11387404 DOI: 10.1152/Jn.2001.85.6.2602  0.603
2001 Finegold AA, Perez FM, Iadarola MJ. In vivo control of NMDA receptor transcript level in motoneurons by viral transduction of a short antisense gene. Brain Research. Molecular Brain Research. 90: 17-25. PMID 11376852 DOI: 10.1016/S0169-328X(01)00062-6  0.366
2001 Olah Z, Karai L, Iadarola MJ. Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1. The Journal of Biological Chemistry. 276: 31163-70. PMID 11333266 DOI: 10.1074/jbc.M101607200  0.331
2001 Benoliel R, Eliav E, Iadarola MJ. Neuropeptide Y in trigeminal ganglion following chronic constriction injury of the rat infraorbital nerve: is there correlation to somatosensory parameters? Pain. 91: 111-21. PMID 11240083 DOI: 10.1016/S0304-3959(00)00417-6  0.334
2001 Olah Z, Szabo T, Karai L, Hough C, Fields RD, Caudle RM, Blumberg PM, Iadarola MJ. Ligand-induced dynamic membrane changes and cell deletion conferred by vanilloid receptor 1. The Journal of Biological Chemistry. 276: 11021-30. PMID 11124944 DOI: 10.1074/Jbc.M008392200  0.609
2000 Feng Z, Hong JS, Qi Q, Han Y, Wilson B, Iadarola M, Tiao N, Bing G. Cloning and expression of MP13 gene from rat hippocampus, a new factor related to guanosine triphosphate regulation Neuroscience Letters. 296: 129-132. PMID 11108998 DOI: 10.1016/S0304-3940(00)01641-4  0.485
2000 Benoliel R, Tanaka M, Caudle RM, Iadarola MJ. Co-localization of N-methyl-D-aspartate receptors and substance P (neurokinin-1) receptors in rat spinal cord. Neuroscience Letters. 291: 61-4. PMID 10978574 DOI: 10.1016/S0304-3940(00)01337-9  0.638
2000 Byers MR, Chudler EH, Iadarola MJ. Chronic tooth pulp inflammation causes transient and persistent expression of Fos in dynorphin-rich regions of rat brainstem. Brain Research. 861: 191-207. PMID 10760482 DOI: 10.1016/S0006-8993(00)01936-3  0.332
1999 Iadarola MJ, Coghill RC. Imaging of pain: recent developments. Current Opinion in Anaesthesiology. 12: 583-9. PMID 17016253 DOI: 10.1097/00001503-199910000-00016  0.634
1999 Szabo T, Olah Z, Iadarola MJ, Blumberg PM. Epidural resiniferatoxin induced prolonged regional analgesia to pain. Brain Research. 840: 92-8. PMID 10517956 DOI: 10.1016/S0006-8993(99)01763-1  0.424
1999 Coghill RC, Sang CN, Maisog JM, Iadarola MJ. Pain intensity processing within the human brain: a bilateral, distributed mechanism. Journal of Neurophysiology. 82: 1934-43. PMID 10515983 DOI: 10.1152/Jn.1999.82.4.1934  0.631
1999 Finegold AA, Mannes AJ, Iadarola MJ. A paracrine paradigm for in vivo gene therapy in the central nervous system: treatment of chronic pain. Human Gene Therapy. 10: 1251-7. PMID 10340556 DOI: 10.1089/10430349950018238  0.679
1999 Benoliel R, Eliav E, Mannes AJ, Caudle RM, Leeman S, Iadarola MJ. Actions of intrathecal diphtheria toxin-substance P fusion protein on models of persistent pain. Pain. 79: 243-53. PMID 10068170 DOI: 10.1016/S0304-3959(98)00170-5  0.786
1998 Caudle RM, Finegold AA, Mannes AJ, Tobias MD, Kenshalo DR, Iadarola MJ. Spinal kappa1 and kappa2 opioid binding sites in rats, guinea pigs, monkeys and humans. Neuroreport. 9: 2523-5. PMID 9721926 DOI: 10.1097/00001756-199808030-00018  0.757
1998 Mannes AJ, Caudle RM, O'Connell BC, Iadarola MJ. Adenoviral gene transfer to spinal-cord neurons: intrathecal vs. intraparenchymal administration. Brain Research. 793: 1-6. PMID 9630472 DOI: 10.1016/S0006-8993(97)01422-4  0.739
1998 Zhang RX, Wang H, Ruda M, Iadarola MJ, Qiao JT. c-Fos expression in NMDA receptor-contained neurons in spinal cord in a rat model of inflammation: a double immunocytochemical study. Brain Research. 795: 282-6. PMID 9622652 DOI: 10.1016/S0006-8993(98)00300-X  0.557
1998 Iadarola MJ, Berman KF, Zeffiro TA, Byas-Smith MG, Gracely RH, Max MB, Bennett GJ. Neural activation during acute capsaicin-evoked pain and allodynia assessed with PET. Brain : a Journal of Neurology. 121: 931-47. PMID 9619195 DOI: 10.1093/brain/121.5.931  0.686
1998 Messersmith DJ, Kim DJ, Iadarola MJ. Transcription factor regulation of prodynorphin gene expression following rat hindpaw inflammation. Brain Research. Molecular Brain Research. 53: 260-9. PMID 9473689 DOI: 10.1016/S0169-328X(97)00308-2  0.356
1998 Coghill RC, Sang CN, Berman KF, Bennett GJ, Iadarola MJ. Global cerebral blood flow decreases during pain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 141-7. PMID 9469155 DOI: 10.1097/00004647-199802000-00003  0.692
1998 Mannes AJ, Finegold AA, Loeb AL, Iadarola MJ. ADENOVIRAL EXPRESSION OF [Greek small letter beta]-ENDORPHIN IN CELL CULTURES Anesthesiology. 89: 1102A. DOI: 10.1097/00000542-199809190-00031  0.569
1998 Coghill RC, Gilron I, Gutierrez C, Iadarola MJ. Hemispheric lateralization of somatosensory processing: Responses to painful and innocuous stimuli Neuroimage. 7: S422. DOI: 10.1016/S1053-8119(18)31255-2  0.579
1997 Caudle RM, Mannes AJ, Iadarola MJ. GR89,696 is a kappa-2 opioid receptor agonist and a kappa-1 opioid receptor antagonist in the guinea pig hippocampus. The Journal of Pharmacology and Experimental Therapeutics. 283: 1342-9. PMID 9400009  0.701
1997 Gu J, Irving SG, Iadarola MJ. URE, an initiator (Inr)-like site, suppresses the promoter of the rat dynorphin gene. Biochemical and Biophysical Research Communications. 231: 172-7. PMID 9070243 DOI: 10.1006/bbrc.1997.6067  0.436
1997 Caudle RM, Mannes AJ, Iadarola MJ. Activation of spinal kappa2 opioid receptors Expert Opinion On Therapeutic Targets. 1: 109-112. DOI: 10.1517/14728222.1.1.109  0.715
1996 Messersmith DJ, Kim DJ, Gu J, Dubner R, Iadarola MJ. c-Jun activation of the DYNCRE3 site in the prodynorphin promoter. Brain Research. Molecular Brain Research. 40: 15-21. PMID 8840008 DOI: 10.1016/0169-328X(96)00029-0  0.669
1996 Ren K, Iadarola MJ, Dubner R. An isobolographic analysis of the effects of N-methyl-D-aspartate and NK1 tachykinin receptor antagonists on inflammatory hyperalgesia in the rat. British Journal of Pharmacology. 117: 196-202. PMID 8825363  0.61
1996 Deutch AY, Lewis DA, Whitehead RE, Elsworth JD, Iadarola MJ, Redmond DE, Roth RH. Effects of D2 dopamine receptor antagonists on Fos protein expression in the striatal complex and entorhinal cortex of the nonhuman primate. Synapse (New York, N.Y.). 23: 182-91. PMID 8807746 DOI: 10.1002/(Sici)1098-2396(199607)23:3<182::Aid-Syn7>3.0.Co;2-4  0.311
1996 Coghill R, Sang C, Berman K, Bennett G, Iadarola M. Global cerebral blood flow decreases during pain: Implications for assessment of regional activation Neuroimage. 3: S326. DOI: 10.1016/S1053-8119(96)80328-4  0.557
1995 Iadarola MJ, Max MB, Berman KF, Byas-Smith MG, Coghill RC, Gracely RH, Bennett GJ. Unilateral decrease in thalamic activity observed with positron emission tomography in patients with chronic neuropathic pain. Pain. 63: 55-64. PMID 8577491 DOI: 10.1016/0304-3959(95)00015-K  0.744
1995 Gu J, Dubner R, Fornace AJ, Iadarola MJ. UREB1, a tyrosine phosphorylated nuclear protein, inhibits p53 transactivation. Oncogene. 11: 2175-8. PMID 7478539  0.578
1994 Messersmith DJ, Gu J, Dubner R, Douglass J, Iadarola MJ. Basal and inducible transcriptional activity of an upstream AP-1/CRE element (DYNCRE3) in the prodynorphin promoter. Molecular and Cellular Neurosciences. 5: 238-45. PMID 8087422 DOI: 10.1006/mcne.1994.1028  0.693
1994 Gu J, Ren K, Dubner R, Iadarola MJ. Cloning of a DNA binding protein that is a tyrosine kinase substrate and recognizes an upstream initiator-like sequence in the promoter of the preprodynorphin gene. Brain Research. Molecular Brain Research. 24: 77-88. PMID 7968380 DOI: 10.1016/0169-328X(94)90120-1  0.678
1994 Iadarola MJ. Stimulus-transcription coupling and immediate-early genes. Correlations and molecular mechanisms Aps Journal. 3: 56-59. DOI: 10.1016/S1058-9139(05)80237-2  0.337
1994 Dubner R, Messersmith DJ, Iadarola MJ. Changes in gene expression following tissue injury Regulatory Peptides. 53: S65-S66. DOI: 10.1016/0167-0115(94)90243-7  0.681
1993 Jian M, Staines WA, Iadarola MJ, Robertson GS. Destruction of the nigrostriatal pathway increases Fos-like immunoreactivity predominantly in striatopallidal neurons. Brain Research. Molecular Brain Research. 19: 156-60. PMID 7689681 DOI: 10.1016/0169-328X(93)90161-H  0.304
1992 Mar EC, Iadarola MJ, Hong JS. Regulation of the expression of proenkephalin mRNA in bovine adrenal chromaffin cells: Role of proto-oncogenes. Molecular and Cellular Neurosciences. 3: 508-17. PMID 19912894 DOI: 10.1016/1044-7431(92)90063-8  0.477
1992 Traub RJ, Pechman P, Iadarola MJ, Gebhart GF. Fos-like proteins in the lumbosacral spinal cord following noxious and non-noxious colorectal distention in the rat. Pain. 49: 393-403. PMID 1408305 DOI: 10.1016/0304-3959(92)90247-9  0.594
1991 Young ST, Porrino LJ, Iadarola MJ. Cocaine induces striatal c-fos-immunoreactive proteins via dopaminergic D1 receptors. Proceedings of the National Academy of Sciences of the United States of America. 88: 1291-5. PMID 1825356 DOI: 10.1073/Pnas.88.4.1291  0.313
1991 Draisci G, Kajander KC, Dubner R, Bennett GJ, Iadarola MJ. Up-regulation of opioid gene expression in spinal cord evoked by experimental nerve injuries and inflammation. Brain Research. 560: 186-92. PMID 1684729 DOI: 10.1016/0006-8993(91)91231-O  0.723
1991 Noguchi K, Kowalski K, Traub R, Solodkin A, Iadarola MJ, Ruda MA. Dynorphin expression and Fos-like immunoreactivity following inflammation induced hyperalgesia are colocalized in spinal cord neurons. Brain Research. Molecular Brain Research. 10: 227-33. PMID 1679515 DOI: 10.1016/0169-328X(91)90065-6  0.696
1991 Hylden JL, Thomas DA, Iadarola MJ, Nahin RL, Dubner R. Spinal opioid analgesic effects are enhanced in a model of unilateral inflammation/hyperalgesia: possible involvement of noradrenergic mechanisms. European Journal of Pharmacology. 194: 135-43. PMID 1676373 DOI: 10.1016/0014-2999(91)90097-A  0.75
1990 Kajander KC, Sahara Y, Iadarola MJ, Bennett GJ. Dynorphin increases in the dorsal spinal cord in rats with a painful peripheral neuropathy. Peptides. 11: 719-28. PMID 1978300 DOI: 10.1016/0196-9781(90)90187-A  0.575
1990 Ruda M, Kowalski K, Traub R, Solodkin A, Iadarola M. Colocalization of opioid peptide and fos protein in a rat model of peripheral inflammation and hyperalgesia Pain. 41: S102. DOI: 10.1016/0304-3959(90)92340-V  0.666
1989 Roth BL, Mehegan JP, Jacobowitz DM, Robey F, Iadarola MJ. Rat brain protein kinase C: purification, antibody production, and quantification in discrete regions of hippocampus. Journal of Neurochemistry. 52: 215-21. PMID 2908889 DOI: 10.1111/J.1471-4159.1989.Tb10919.X  0.448
1989 Roth BL, Iadarola MJ, Mehegan JP, Jacobowitz DM. Immunohistochemical distribution of beta-protein kinase C in rat hippocampus determined with an antibody against a synthetic peptide sequence. Brain Research Bulletin. 22: 893-7. PMID 2765948 DOI: 10.1016/0361-9230(89)90034-8  0.439
1989 Traub RJ, Iadarola MJ, Ruda MA. Effect of multiple dorsal rhizotomies on calcitonin gene-related peptide-like immunoreactivity in the lumbosacral dorsal spinal cord of the cat: a radioimmunoassay analysis. Peptides. 10: 979-83. PMID 2608558 DOI: 10.1016/0196-9781(89)90179-4  0.673
1989 Draisci G, Iadarola MJ. Temporal analysis of increases in c-fos, preprodynorphin and preproenkephalin mRNAs in rat spinal cord. Brain Research. Molecular Brain Research. 6: 31-7. PMID 2570339 DOI: 10.1016/0169-328X(89)90025-9  0.358
1989 Nahin RL, Hylden JL, Iadarola MJ, Dubner R. Peripheral inflammation is associated with increased dynorphin immunoreactivity in both projection and local circuit neurons in the superficial dorsal horn of the rat lumbar spinal cord. Neuroscience Letters. 96: 247-52. PMID 2566136 DOI: 10.1016/0304-3940(89)90386-8  0.746
1988 Iadarola MJ, Brady LS, Draisci G, Dubner R. Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding. Pain. 35: 313-26. PMID 2906426 DOI: 10.1016/0304-3959(88)90141-8  0.678
1988 Iadarola MJ, Flores CM, Cadet JL, Suddath R, Illowsky B, Berman KF. Met5-enkephalin-Arg6-Gly7-Leu8 immunoreactivity in rat and human cerebrospinal fluid: influence of neuroleptic drugs and electroconvulsive shock. Brain Research. 474: 75-85. PMID 2905617 DOI: 10.1016/0006-8993(88)90670-1  0.307
1988 Iadarola MJ, Douglass J, Civelli O, Naranjo JR. Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization. Brain Research. 455: 205-12. PMID 2900057 DOI: 10.1016/0006-8993(88)90078-9  0.378
1988 Ruda MA, Iadarola MJ, Cohen LV, Young WS. In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia. Proceedings of the National Academy of Sciences of the United States of America. 85: 622-6. PMID 2893375 DOI: 10.1073/Pnas.85.2.622  0.581
1987 Ruda MA, Iadarola M, Cohen L. Immunocytochemistry and insitu hybridization identify changes in neuronal dynorphin levels in a rat model of peripheral inflammation Pain. 30: S241. DOI: 10.1016/0304-3959(87)91542-9  0.532
1987 Iadarola MJ, Flores CM, Naranjo JR. Increase in spinal cord dynorphin biosynthesis during peripheral inflammation: Behavioral, neuropeptide and mRNA studies Pain. 30: S240. DOI: 10.1016/0304-3959(87)91541-7  0.314
1986 Ferrarese C, Iadarola MJ, Yang HY, Costa E. Peripheral and central origin of Phe-Met-Arg-Phe-amide immunoreactivity in rat spinal cord. Regulatory Peptides. 13: 245-52. PMID 3704197 DOI: 10.1016/0167-0115(86)90043-1  0.333
1986 Nicoletti F, Wroblewski JT, Iadarola MJ, Costa E. Serine-O-phosphate, an endogenous metabolite, inhibits the stimulation of inositol phospholipid hydrolysis elicited by ibotenic acid in rat hippocampal slices. Neuropharmacology. 25: 335-8. PMID 3084992 DOI: 10.1016/0028-3908(86)90262-5  0.602
1986 Nicoletti F, Iadarola MJ, Wroblewski JT, Costa E. Excitatory amino acid recognition sites coupled with inositol phospholipid metabolism: developmental changes and interaction with alpha 1-adrenoceptors. Proceedings of the National Academy of Sciences of the United States of America. 83: 1931-5. PMID 2869493 DOI: 10.1073/Pnas.83.6.1931  0.602
1986 Nicoletti F, Meek JL, Iadarola MJ, Chuang DM, Roth BL, Costa E. Coupling of inositol phospholipid metabolism with excitatory amino acid recognition sites in rat hippocampus. Journal of Neurochemistry. 46: 40-6. PMID 2866236 DOI: 10.1111/J.1471-4159.1986.Tb12922.X  0.659
1986 Garant DS, Iadarola MJ, Gale K. Substance P antagonists in substantia nigra are anticonvulsant. Brain Research. 382: 372-8. PMID 2428445 DOI: 10.1016/0006-8993(86)91347-8  0.631
1986 Iadarola MJ, Tang J, Costa E, Yang HY. Analgesic activity and release of [MET5]enkephalin-Arg6-Gly7-Leu8 from rat spinal cord in vivo. European Journal of Pharmacology. 121: 39-48. PMID 2420613 DOI: 10.1016/0014-2999(86)90390-0  0.378
1983 Gale K, Iadarola MJ, Casu M. Anticonvulsant action of GABAergic drugs: cellular and anatomical localization of their site of action in vivo. Progress in Clinical and Biological Research. 124: 39-62. PMID 6878396  0.579
1982 Iadarola MJ, Gale K. Substantia nigra: site of anticonvulsant activity mediated by gamma-aminobutyric acid. Science (New York, N.Y.). 218: 1237-40. PMID 7146907 DOI: 10.1126/Science.7146907  0.619
1981 Iadarola MJ, Gale K. Cellular compartments of GABA in brain and their relationship to anticonvulsant activity. Molecular and Cellular Biochemistry. 39: 305-29. PMID 6273710 DOI: 10.1007/Bf00232582  0.618
1980 Gale K, Iadarola M. Drug-induced elevation of GABA after intracerebral microinjection: site of anticonvulsant action. European Journal of Pharmacology. 68: 233-5. PMID 7202489 DOI: 10.1016/0014-2999(80)90330-1  0.61
1980 Gale K, Iadarola MJ. Seizure protection and increased nerve-terminal GABA: delayed effects of GABA transaminase inhibition. Science (New York, N.Y.). 208: 288-91. PMID 6768130  0.579
1980 Gale K, Iadarola MJ. GABAergic denervation of rat substantia nigra: functional and pharmacological properties. Brain Research. 183: 217-23. PMID 6244049 DOI: 10.1016/0006-8993(80)90133-X  0.62
1980 Iadarola M, Gale K. Evaluation of increases in nerve terminal-dependent vs nerve terminal-independent compartments of GABA in vivo Brain Research Bulletin. 5: 13-19. DOI: 10.1016/0361-9230(80)90003-9  0.617
1979 Iadarola MJ, Gale K. Dissociation between drug-induced increases in nerve terminal and non-nerve terminal pools of GABA in vivo. European Journal of Pharmacology. 59: 125-9. PMID 389641 DOI: 10.1016/0014-2999(79)90034-7  0.624
1979 Iadarola MJ, Raines A, Gale K. Differential effects of n-dipropylacetate and amino-oxyacetic acid on gamma-aminobutyric acid levels in discrete areas of rat brain. Journal of Neurochemistry. 33: 1119-23. PMID 387917 DOI: 10.1111/J.1471-4159.1979.Tb05250.X  0.612
1979 Iadarola M, Gale K. Evaluation of increases in nerve-terminal-dependent vs. nerve-terminal-independent compartments of GABA : correlation with anticonvulsant effects of gaba-t inhibition Brain Research Bulletin. 4: 686. DOI: 10.1016/0361-9230(79)90126-6  0.581
1975 Levy HB, Baer G, Baron S, Buckler CE, Gibbs CJ, Iadarola MJ, London WT, Rice J. A modified polyriboinosinic-polyribocytidylic acid complex that induces interferon in primates. The Journal of Infectious Diseases. 132: 434-9. PMID 810520 DOI: 10.1093/Infdis/132.4.434  0.455
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