| Year |
Citation |
Score |
| 2023 |
Xu X, Shonberg J, Kaindl J, Clark MJ, Stößel A, Maul L, Mayer D, Hübner H, Hirata K, Venkatakrishnan AJ, Dror RO, Kobilka BK, Sunahara RK, Liu X, Gmeiner P. Constrained catecholamines gain βAR selectivity through allosteric effects on pocket dynamics. Nature Communications. 14: 2138. PMID 37059717 DOI: 10.1038/s41467-023-37808-y |
0.337 |
|
| 2023 |
Huang SK, Picard LP, Rahmatullah RSM, Pandey A, Van Eps N, Sunahara RK, Ernst OP, Sljoka A, Prosser RS. Mapping the conformational landscape of the stimulatory heterotrimeric G protein. Nature Structural & Molecular Biology. PMID 36997760 DOI: 10.1038/s41594-023-00957-1 |
0.438 |
|
| 2021 |
Huang SK, Pandey A, Tran DP, Villanueva NL, Kitao A, Sunahara RK, Sljoka A, Prosser RS. Delineating the conformational landscape of the adenosine A receptor during G protein coupling. Cell. PMID 33743210 DOI: 10.1016/j.cell.2021.02.041 |
0.47 |
|
| 2020 |
Maeda S, Xu J, N Kadji FM, Clark MJ, Zhao J, Tsutsumi N, Aoki J, Sunahara RK, Inoue A, Garcia KC, Kobilka BK. Structure and selectivity engineering of the M muscarinic receptor toxin complex. Science (New York, N.Y.). 369: 161-167. PMID 32646996 DOI: 10.1126/Science.Aax2517 |
0.47 |
|
| 2020 |
Yin J, Chen KM, Clark MJ, Hijazi M, Kumari P, Bai XC, Sunahara RK, Barth P, Rosenbaum DM. Structure of a D2 dopamine receptor-G-protein complex in a lipid membrane. Nature. PMID 32528175 DOI: 10.1038/S41586-020-2379-5 |
0.536 |
|
| 2020 |
Liu X, Kaindl J, Korczynska M, Stößel A, Dengler D, Stanek M, Hübner H, Clark MJ, Mahoney J, Matt RA, Xu X, Hirata K, Shoichet BK, Sunahara RK, Kobilka BK, et al. An allosteric modulator binds to a conformational hub in the β adrenergic receptor. Nature Chemical Biology. PMID 32483378 DOI: 10.1038/S41589-020-0549-2 |
0.469 |
|
| 2019 |
Nguyen AH, Thomsen ARB, Cahill TJ, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, ... ... Sunahara R, et al. Structure of an endosomal signaling GPCR-G protein-β-arrestin megacomplex. Nature Structural & Molecular Biology. PMID 31740855 DOI: 10.1038/S41594-019-0330-Y |
0.49 |
|
| 2018 |
Glukhova A, Draper-Joyce CJ, Sunahara RK, Christopoulos A, Wootten D, Sexton PM. Rules of Engagement: GPCRs and G Proteins. Acs Pharmacology & Translational Science. 1: 73-83. PMID 32219204 DOI: 10.1021/acsptsci.8b00026 |
0.457 |
|
| 2018 |
Liu H, Hofmann J, Fish I, Schaake B, Eitel K, Bartuschat A, Kaindl J, Rampp H, Banerjee A, Hübner H, Clark MJ, Vincent SG, Fisher JT, Heinrich MR, Hirata K, ... ... Sunahara RK, et al. Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists. Proceedings of the National Academy of Sciences of the United States of America. PMID 30404914 DOI: 10.1073/Pnas.1813988115 |
0.366 |
|
| 2018 |
Masureel M, Zou Y, Picard LP, van der Westhuizen E, Mahoney JP, Rodrigues JPGLM, Mildorf TJ, Dror RO, Shaw DE, Bouvier M, Pardon E, Steyaert J, Sunahara RK, Weis WI, Zhang C, et al. Structural insights into binding specificity, efficacy and bias of a βAR partial agonist. Nature Chemical Biology. 14: 1059-1066. PMID 30327561 DOI: 10.1038/S41589-018-0145-X |
0.476 |
|
| 2018 |
Valnohova J, Kowalski-Jahn M, Sunahara RK, Schulte G. Functional dissection of the N-terminal extracellular domains of Frizzled 6 reveals their roles for receptor localization and Dishevelled recruitment. The Journal of Biological Chemistry. PMID 30237173 DOI: 10.1074/Jbc.Ra118.004763 |
0.454 |
|
| 2018 |
Livingston KE, Mahoney JP, Manglik A, Sunahara R, Traynor JR. Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor. Elife. 7. PMID 29932421 DOI: 10.7554/Elife.32499 |
0.483 |
|
| 2018 |
Ye L, Neale C, Sljoka A, Lyda B, Pichugin D, Tsuchimura N, Larda ST, Pomès R, García AE, Ernst OP, Sunahara RK, Prosser RS. Mechanistic insights into allosteric regulation of the A adenosine G protein-coupled receptor by physiological cations. Nature Communications. 9: 1372. PMID 29636462 DOI: 10.1038/S41467-018-03314-9 |
0.527 |
|
| 2018 |
Korczynska M, Clark MJ, Valant C, Xu J, Moo EV, Albold S, Weiss DR, Torosyan H, Huang W, Kruse AC, Lyda BR, May LT, Baltos JA, Sexton PM, Kobilka BK, ... ... Sunahara RK, et al. Structure-based discovery of selective positive allosteric modulators of antagonists for the Mmuscarinic acetylcholine receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 29453275 DOI: 10.1073/Pnas.1718037115 |
0.433 |
|
| 2018 |
Livingston KE, Mahoney JP, Manglik A, Sunahara RK, Traynor JR. Author response: Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor Elife. DOI: 10.7554/Elife.32499.015 |
0.355 |
|
| 2017 |
Fish I, Stoessel A, Eitel K, Valant C, Albold S, Hübner H, Möller D, Clark MJ, Sunahara RK, Christopoulos A, Shoichet BK, Gmeiner P. Structure-based design and discovery of new M2 receptor agonists. Journal of Medicinal Chemistry. PMID 29094937 DOI: 10.1021/Acs.Jmedchem.7B01113 |
0.417 |
|
| 2017 |
Malik RU, Dysthe M, Ritt M, Sunahara RK, Sivaramakrishnan S. ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells. Scientific Reports. 7: 7749. PMID 28798477 DOI: 10.1038/S41598-017-08029-3 |
0.47 |
|
| 2017 |
O'Hayre M, Eichel K, Avino S, Zhao X, Steffen DJ, Feng X, Kawakami K, Aoki J, Messer K, Sunahara R, Inoue A, von Zastrow M, Gutkind JS. Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK. Science Signaling. 10. PMID 28634209 DOI: 10.1126/Scisignal.Aal3395 |
0.351 |
|
| 2017 |
Cai Y, Liu Y, Culhane KJ, DeVree BT, Yang Y, Sunahara RK, Yan ECY. Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptor. Plos One. 12: e0179568. PMID 28609478 DOI: 10.1371/Journal.Pone.0179568 |
0.806 |
|
| 2017 |
Brea RJ, Cole CM, Lyda BR, Ye L, Prosser RS, Sunahara RK, Devaraj NK. In Situ Reconstitution of the Adenosine A2A Receptor in Spontaneously Formed Synthetic Liposomes. Journal of the American Chemical Society. PMID 28263576 DOI: 10.1021/Jacs.6B12830 |
0.507 |
|
| 2016 |
Mahoney JP, Sunahara RK. Mechanistic insights into GPCR-G protein interactions. Current Opinion in Structural Biology. 41: 247-254. PMID 27871057 DOI: 10.1016/J.Sbi.2016.11.005 |
0.581 |
|
| 2016 |
Thomsen AR, Plouffe B, Cahill TJ, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, et al. GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell. PMID 27499021 DOI: 10.1016/J.Cell.2016.07.004 |
0.528 |
|
| 2016 |
DeVree BT, Mahoney JP, Vélez-Ruiz GA, Rasmussen SG, Kuszak AJ, Edwald E, Fung JJ, Manglik A, Masureel M, Du Y, Matt RA, Pardon E, Steyaert J, Kobilka BK, Sunahara RK. Allosteric coupling from G protein to the agonist-binding pocket in GPCRs. Nature. PMID 27362234 DOI: 10.1038/Nature18324 |
0.831 |
|
| 2016 |
Sunahara RK, Insel PA. The molecular pharmacology of G protein signaling then and now: A tribute to Alfred G. Gilman. Molecular Pharmacology. PMID 26984025 DOI: 10.1124/Mol.116.104216 |
0.466 |
|
| 2015 |
Makley LN, McMenimen KA, DeVree BT, Goldman JW, McGlasson BN, Rajagopal P, Dunyak BM, McQuade TJ, Thompson AD, Sunahara R, Klevit RE, Andley UP, Gestwicki JE. Pharmacological chaperone for α-crystallin partially restores transparency in cataract models. Science (New York, N.Y.). 350: 674-7. PMID 26542570 DOI: 10.1126/Science.Aac9145 |
0.746 |
|
| 2015 |
Dror RO, Mildorf TJ, Hilger D, Manglik A, Borhani DW, Arlow DH, Philippsen A, Villanueva N, Yang Z, Lerch MT, Hubbell WL, Kobilka BK, Sunahara RK, Shaw DE. SIGNAL TRANSDUCTION. Structural basis for nucleotide exchange in heterotrimeric G proteins. Science (New York, N.Y.). 348: 1361-5. PMID 26089515 DOI: 10.1126/Science.Aaa5264 |
0.497 |
|
| 2013 |
Malik RU, Ritt M, DeVree BT, Neubig RR, Sunahara RK, Sivaramakrishnan S. Detection of G protein-selective G protein-coupled receptor (GPCR) conformations in live cells. The Journal of Biological Chemistry. 288: 17167-78. PMID 23629648 DOI: 10.1074/Jbc.M113.464065 |
0.802 |
|
| 2013 |
Irannejad R, Tomshine JC, Tomshine JR, Chevalier M, Mahoney JP, Steyaert J, Rasmussen SG, Sunahara RK, El-Samad H, Huang B, von Zastrow M. Conformational biosensors reveal GPCR signalling from endosomes. Nature. 495: 534-8. PMID 23515162 DOI: 10.1038/Nature12000 |
0.533 |
|
| 2013 |
Chung KY, Day PW, Vélez-Ruiz G, Sunahara RK, Kobilka BK. Identification of GPCR-interacting cytosolic proteins using HDL particles and mass spectrometry-based proteomic approach. Plos One. 8: e54942. PMID 23372797 DOI: 10.1371/Journal.Pone.0054942 |
0.505 |
|
| 2013 |
Mitra N, Liu Y, Liu J, Serebryany E, Mooney V, DeVree BT, Sunahara RK, Yan EC. Calcium-dependent ligand binding and G-protein signaling of family B GPCR parathyroid hormone 1 receptor purified in nanodiscs. Acs Chemical Biology. 8: 617-25. PMID 23237450 DOI: 10.1021/Cb300466N |
0.806 |
|
| 2012 |
Manglik A, Kruse AC, Kobilka TS, Thian FS, Mathiesen JM, Sunahara RK, Pardo L, Weis WI, Kobilka BK, Granier S. Crystal structure of the µ-opioid receptor bound to a morphinan antagonist. Nature. 485: 321-6. PMID 22437502 DOI: 10.1038/Nature10954 |
0.457 |
|
| 2011 |
Chung KY, Rasmussen SG, Liu T, Li S, DeVree BT, Chae PS, Calinski D, Kobilka BK, Woods VL, Sunahara RK. Conformational changes in the G protein Gs induced by the β2 adrenergic receptor. Nature. 477: 611-5. PMID 21956331 DOI: 10.1038/Nature10488 |
0.835 |
|
| 2011 |
Westfield GH, Rasmussen SG, Su M, Dutta S, DeVree BT, Chung KY, Calinski D, Velez-Ruiz G, Oleskie AN, Pardon E, Chae PS, Liu T, Li S, Woods VL, Steyaert J, ... ... Sunahara RK, et al. Structural flexibility of the G alpha s alpha-helical domain in the beta2-adrenoceptor Gs complex. Proceedings of the National Academy of Sciences of the United States of America. 108: 16086-91. PMID 21914848 DOI: 10.1073/Pnas.1113645108 |
0.804 |
|
| 2011 |
Vélez-Ruiz GA, Sunahara RK. Reconstitution of G protein-coupled receptors into a model bilayer system: reconstituted high-density lipoprotein particles. Methods in Molecular Biology (Clifton, N.J.). 756: 167-82. PMID 21870225 DOI: 10.1007/978-1-61779-160-4_8 |
0.385 |
|
| 2011 |
Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, ... ... Sunahara RK, et al. Crystal structure of the β2 adrenergic receptor-Gs protein complex. Nature. 477: 549-55. PMID 21772288 DOI: 10.1038/Nature10361 |
0.835 |
|
| 2011 |
Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, et al. Structure and function of an irreversible agonist-β(2) adrenoceptor complex. Nature. 469: 236-40. PMID 21228876 DOI: 10.1038/Nature09665 |
0.833 |
|
| 2011 |
Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS, Schnapp A, Konetzki I, Sunahara RK, Gellman SH, Pautsch A, et al. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature. 469: 175-80. PMID 21228869 DOI: 10.1038/Nature09648 |
0.824 |
|
| 2009 |
Fung JJ, Deupi X, Pardo L, Yao XJ, Velez-Ruiz GA, Devree BT, Sunahara RK, Kobilka BK. Ligand-regulated oligomerization of beta(2)-adrenoceptors in a model lipid bilayer. The Embo Journal. 28: 3315-28. PMID 19763081 DOI: 10.1038/Emboj.2009.267 |
0.8 |
|
| 2009 |
Kuszak AJ, Pitchiaya S, Anand JP, Mosberg HI, Walter NG, Sunahara RK. Purification and functional reconstitution of monomeric mu-opioid receptors: allosteric modulation of agonist binding by Gi2. The Journal of Biological Chemistry. 284: 26732-41. PMID 19542234 DOI: 10.1074/Jbc.M109.026922 |
0.534 |
|
| 2009 |
Yao XJ, Vélez Ruiz G, Whorton MR, Rasmussen SG, DeVree BT, Deupi X, Sunahara RK, Kobilka B. The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 9501-6. PMID 19470481 DOI: 10.1073/Pnas.0811437106 |
0.713 |
|
| 2009 |
Collins GT, Truccone A, Haji-Abdi F, Newman AH, Grundt P, Rice KC, Husbands SM, Greedy BM, Enguehard-Gueiffier C, Gueiffier A, Chen J, Wang S, Katz JL, Grandy DK, Sunahara RK, et al. Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice. The Journal of Pharmacology and Experimental Therapeutics. 329: 210-7. PMID 19136638 DOI: 10.1124/Jpet.108.144048 |
0.309 |
|
| 2008 |
Whorton MR, Jastrzebska B, Park PS, Fotiadis D, Engel A, Palczewski K, Sunahara RK. Efficient coupling of transducin to monomeric rhodopsin in a phospholipid bilayer. The Journal of Biological Chemistry. 283: 4387-94. PMID 18033822 DOI: 10.1074/Jbc.M703346200 |
0.789 |
|
| 2007 |
Cunliffe JM, Sunahara RK, Kennedy RT. Detection of g protein coupled receptor mediated adenylyl cyclase activity by capillary electrophoresis using fluorescently labeled ATP. Analytical Chemistry. 79: 7534-9. PMID 17718540 DOI: 10.1021/Ac071203+ |
0.523 |
|
| 2007 |
Cunliffe JM, Whorton MR, Sunahara RK, Kennedy RT. A CE assay for the detection of agonist-stimulated adenylyl cyclase activity. Electrophoresis. 28: 1913-20. PMID 17480040 DOI: 10.1002/Elps.200600571 |
0.786 |
|
| 2007 |
Whorton MR, Bokoch MP, Rasmussen SG, Huang B, Zare RN, Kobilka B, Sunahara RK. A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein. Proceedings of the National Academy of Sciences of the United States of America. 104: 7682-7. PMID 17452637 DOI: 10.1073/Pnas.0611448104 |
0.817 |
|
| 2007 |
Benson MD, Li QJ, Kieckhafer K, Dudek D, Whorton MR, Sunahara RK, Iñiguez-Lluhà JA, Martens JR. SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5. Proceedings of the National Academy of Sciences of the United States of America. 104: 1805-10. PMID 17261810 DOI: 10.1073/Pnas.0606702104 |
0.715 |
|
| 2007 |
Bodenstein J, Sunahara RK, Neubig RR. N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells. Molecular Pharmacology. 71: 1040-50. PMID 17220356 DOI: 10.1124/Mol.106.029397 |
0.44 |
|
| 2007 |
Roman DL, Talbot JN, Roof RA, Sunahara RK, Traynor JR, Neubig RR. Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Molecular Pharmacology. 71: 169-75. PMID 17012620 DOI: 10.1124/Mol.106.028670 |
0.486 |
|
| 2006 |
Giguère P, Rochdi MD, Laroche G, Dupré E, Whorton MR, Sunahara RK, Claing A, Dupuis G, Parent JL. ARF6 activation by Galpha q signaling: Galpha q forms molecular complexes with ARNO and ARF6. Cellular Signalling. 18: 1988-94. PMID 16650966 DOI: 10.1016/J.Cellsig.2006.03.003 |
0.772 |
|
| 2006 |
Roof RA, Jin Y, Roman DL, Sunahara RK, Ishii M, Mosberg HI, Neubig RR. Mechanism of action and structural requirements of constrained peptide inhibitors of RGS proteins. Chemical Biology & Drug Design. 67: 266-74. PMID 16629824 DOI: 10.1111/J.1747-0285.2006.00373.X |
0.422 |
|
| 2006 |
Cunliffe JM, Sunahara RK, Kennedy RT. Detection of adenylyl cyclase activity using a fluorescent ATP substrate and capillary electrophoresis. Analytical Chemistry. 78: 1731-8. PMID 16536404 DOI: 10.1021/Ac0521201 |
0.322 |
|
| 2005 |
Morishima Y, Peng HM, Lin HL, Hollenberg PF, Sunahara RK, Osawa Y, Pratt WB. Regulation of cytochrome P450 2E1 by heat shock protein 90-dependent stabilization and CHIP-dependent proteasomal degradation. Biochemistry. 44: 16333-40. PMID 16331994 DOI: 10.1021/Bi0515570 |
0.31 |
|
| 2005 |
Draganov DI, Teiber JF, Speelman A, Osawa Y, Sunahara R, La Du BN. Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. Journal of Lipid Research. 46: 1239-47. PMID 15772423 DOI: 10.1194/Jlr.M400511-Jlr200 |
0.301 |
|
| 2005 |
Vadakkadathmeethal K, Felczak A, Davignon I, Collins J, Sunahara RK. Cloning and characterization of the G protein betagamma subunits from Trichoplusia ni (High Five cells). Insect Biochemistry and Molecular Biology. 35: 333-45. PMID 15763469 DOI: 10.1016/J.Ibmb.2004.12.011 |
0.48 |
|
| 2005 |
Chang FJ, Lemme S, Sun Q, Sunahara RK, Beuve A. Nitric oxide-dependent allosteric inhibitory role of a second nucleotide binding site in soluble guanylyl cyclase Journal of Biological Chemistry. 280: 11513-11519. PMID 15649897 DOI: 10.1074/Jbc.M412203200 |
0.37 |
|
| 2005 |
Jameson EE, Roof RA, Whorton MH, Mosberg HI, Sunahara RK, Neubig RR, Kennedy RT. Real-time detection of basal and stimulated G protein GTPase activity using fluorescent GTP analogues Journal of Biological Chemistry. 280: 7712-7719. PMID 15613467 DOI: 10.1074/Jbc.M413810200 |
0.396 |
|
| 2004 |
Whelan RJ, Sunahara RK, Neubig RR, Kennedy RT. Affinity assays using fluorescence anisotropy with capillary electrophoresis separation. Analytical Chemistry. 76: 7380-6. PMID 15595883 DOI: 10.1021/Ac0489566 |
0.316 |
|
| 2004 |
Klein C, Heyduk T, Sunahara RK. Zinc inhibition of adenylyl cyclase correlates with conformational changes in the enzyme. Cellular Signalling. 16: 1177-85. PMID 15240012 DOI: 10.1016/J.Cellsig.2004.03.008 |
0.37 |
|
| 2004 |
Krumins AM, Barker SA, Huang C, Sunahara RK, Yu K, Wilkie TM, Gold SJ, Mumby SM. Differentially regulated expression of endogenous RGS4 and RGS7. The Journal of Biological Chemistry. 279: 2593-9. PMID 14604980 DOI: 10.1074/Jbc.M311600200 |
0.403 |
|
| 2003 |
Jameson EE, Cunliffe JM, Neubig RR, Sunahara RK, Kennedy RT. Detection of G proteins by affinity probe capillary electrophoresis using a fluorescently labeled GTP analogue Analytical Chemistry. 75: 4297-4304. PMID 14632149 DOI: 10.1021/Ac0342976 |
0.369 |
|
| 2003 |
Morishima Y, Kanelakis KC, Murphy PJ, Lowe ER, Jenkins GJ, Osawa Y, Sunahara RK, Pratt WB. The hsp90 cochaperone p23 is the limiting component of the multiprotein hsp90/hsp70-based chaperone system in vivo where it acts to stabilize the client protein: hsp90 complex. The Journal of Biological Chemistry. 278: 48754-63. PMID 14507910 DOI: 10.1074/Jbc.M309814200 |
0.409 |
|
| 2003 |
Whorton MR, Sunahara RK. Adenylyl Cyclases Handbook of Cell Signaling. 2: 419-426. DOI: 10.1016/B978-012124546-7/50551-9 |
0.726 |
|
| 2002 |
Klein C, Sunahara RK, Hudson TY, Heyduk T, Howlett AC. Zinc inhibition of cAMP signaling. The Journal of Biological Chemistry. 277: 11859-65. PMID 11805091 DOI: 10.1074/Jbc.M108808200 |
0.558 |
|
| 2002 |
Tesmer JJ, Sunahara RK, Fancy DA, Gilman AG, Sprang SR. Crystallization of complex between soluble domains of adenylyl cyclase and activated Gs alpha. Methods in Enzymology. 345: 198-206. PMID 11665605 DOI: 10.1016/S0076-6879(02)45017-3 |
0.509 |
|
| 2002 |
Hatley ME, Gilman AG, Sunahara RK. Expression, purification, and assay of cytosolic (catalytic) domains of membrane-bound mammalian adenylyl cyclases. Methods in Enzymology. 345: 127-40. PMID 11665600 DOI: 10.1016/S0076-6879(02)45012-4 |
0.592 |
|
| 2001 |
Wang L, Sunahara RK, Krumins A, Perkins G, Crochiere ML, Mackey M, Bell S, Ellisman MH, Taylor SS. Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein. Proceedings of the National Academy of Sciences of the United States of America. 98: 3220-5. PMID 11248059 DOI: 10.1073/Pnas.051633398 |
0.37 |
|
| 2000 |
Tesmer JJ, Dessauer CW, Sunahara RK, Murray LD, Johnson RA, Gilman AG, Sprang SR. Molecular basis for P-site inhibition of adenylyl cyclase. Biochemistry. 39: 14464-71. PMID 11087399 DOI: 10.1021/Bi0015562 |
0.7 |
|
| 2000 |
Hatley ME, Benton BK, Xu J, Manfredi JP, Gilman AG, Sunahara RK. Isolation and characterization of constitutively active mutants of mammalian adenylyl cyclase Journal of Biological Chemistry. 275: 38626-38632. PMID 10982815 DOI: 10.1074/Jbc.M007148200 |
0.621 |
|
| 2000 |
Ciliax BJ, Nash N, Heilman C, Sunahara R, Hartney A, Tiberi M, Rye DB, Caron MG, Niznik HB, Levey AI. Dopamine D(5) receptor immunolocalization in rat and monkey brain. Synapse (New York, N.Y.). 37: 125-45. PMID 10881034 DOI: 10.1002/1098-2396(200008)37:2<125::Aid-Syn7>3.0.Co;2-7 |
0.364 |
|
| 1999 |
Tesmer JJ, Sunahara RK, Johnson RA, Gosselin G, Gilman AG, Sprang SR. Two-metal-Ion catalysis in adenylyl cyclase. Science (New York, N.Y.). 285: 756-60. PMID 10427002 DOI: 10.1126/Science.285.5428.756 |
0.559 |
|
| 1998 |
Sunahara RK, Beuve A, Tesmer JJ, Sprang SR, Garbers DL, Gilman AG. Exchange of substrate and inhibitor specificities between adenylyl and guanylyl cyclases. The Journal of Biological Chemistry. 273: 16332-8. PMID 9632695 DOI: 10.1074/Jbc.273.26.16332 |
0.589 |
|
| 1997 |
Tesmer JJ, Sunahara RK, Gilman AG, Sprang SR. Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS. Science (New York, N.Y.). 278: 1907-16. PMID 9417641 DOI: 10.1126/Science.278.5345.1907 |
0.619 |
|
| 1997 |
Sunahara RK, Tesmer JJ, Gilman AG, Sprang SR. Crystal structure of the adenylyl cyclase activator Gsalpha. Science (New York, N.Y.). 278: 1943-7. PMID 9395396 DOI: 10.1126/Science.278.5345.1943 |
0.663 |
|
| 1997 |
Svenningsson P, Le Moine C, Kull B, Sunahara R, Bloch B, Fredholm BB. Cellular expression of adenosine A2A receptor messenger RNA in the rat central nervous system with special reference to dopamine innervated areas. Neuroscience. 80: 1171-85. PMID 9284069 DOI: 10.1016/S0306-4522(97)00180-2 |
0.327 |
|
| 1997 |
Sunahara RK, Dessauer CW, Whisnant RE, Kleuss C, Gilman AG. Interaction of G(sα) with the cytosolic domains of mammalian adenylyl cyclase Journal of Biological Chemistry. 272: 22265-22271. PMID 9268375 DOI: 10.1074/Jbc.272.35.22265 |
0.734 |
|
| 1996 |
Sunahara RK, Dessauer CW, Gilman AG. Complexity and diversity of mammalian adenylyl cyclases Annual Review of Pharmacology and Toxicology. 36: 461-480. PMID 8725398 DOI: 10.1146/Annurev.Pa.36.040196.002333 |
0.775 |
|
| 1994 |
Seeman P, Sunahara RK, Niznik HB. Receptor-receptor link in membranes revealed by ligand competition: example for dopamine D1 and D2 receptors. Synapse (New York, N.Y.). 17: 62-4. PMID 8042146 DOI: 10.1002/Syn.890170107 |
0.413 |
|
| 1993 |
Ohara K, Ulpian C, Seeman P, Sunahara RK, Van Tol HHM, Niznik HB. Schizophrenia: Dopamine D1 receptor sequence is normal, but has DNA polymorphisms Neuropsychopharmacology. 8: 131-135. PMID 8471124 DOI: 10.1038/Npp.1993.14 |
0.316 |
|
| 1993 |
Gelernter J, Kennedy JL, Grandy DK, Zhou QY, Civelli O, Pauls DL, Pakstis A, Kurlan R, Sunahara RK, Niznik HB. Exclusion of close linkage of Tourette's syndrome to D1 dopamine receptor. The American Journal of Psychiatry. 150: 449-53. PMID 8434661 DOI: 10.1176/Ajp.150.3.449 |
0.308 |
|
| 1993 |
Levey AI, Hersch SM, Rye DB, Sunahara RK, Niznik HB, Kitt CA, Price DL, Maggio R, Brann MR, Ciliax BJ. Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies. Proceedings of the National Academy of Sciences of the United States of America. 90: 8861-5. PMID 8415621 DOI: 10.1073/Pnas.90.19.8861 |
0.33 |
|
| 1993 |
Sugamori KS, Sunahara RK, Guan HC, Bulloch AG, Tensen CP, Seeman P, Niznik HB, Van Tol HH. Serotonin receptor cDNA cloned from Lymnaea stagnalis. Proceedings of the National Academy of Sciences of the United States of America. 90: 11-5. PMID 8093556 DOI: 10.1073/Pnas.90.1.11 |
0.367 |
|
| 1993 |
Sunahara RK, Seeman P, Tol HHMV, Niznik HB. Dopamine Receptors and Antipsychotic Drug Response British Journal of Psychiatry. 163: 31-38. DOI: 10.1192/S000712500029257X |
0.382 |
|
| 1992 |
Mengod G, Villaró MT, Landwehrmeyer GB, Martinez-Mir MI, Niznik HB, Sunahara RK, Seeman P, O'Dowd BF, Probst A, Palacios JM. Visualization of dopamine D1, D2 and D3 receptor mRNAs in human and rat brain. Neurochemistry International. 20: 33S-43S. PMID 1365451 DOI: 10.1016/0197-0186(92)90208-9 |
0.312 |
|
| 1992 |
Seeman P, Guan HC, Civelli O, Van Tol HH, Sunahara RK, Niznik HB. The cloned dopamine D2 receptor reveals different densities for dopamine receptor antagonist ligands. Implications for human brain positron emission tomography. European Journal of Pharmacology. 227: 139-46. PMID 1358662 DOI: 10.1016/0922-4106(92)90121-B |
0.362 |
|
| 1992 |
Demchyshyn L, Sunahara RK, Miller K, Teitler M, Hoffman BJ, Kennedy JL, Seeman P, Van Tol HH, Niznik HB. A human serotonin 1D receptor variant (5HT1D beta) encoded by an intronless gene on chromosome 6. Proceedings of the National Academy of Sciences of the United States of America. 89: 5522-6. PMID 1351684 DOI: 10.1073/Pnas.89.12.5522 |
0.442 |
|
| 1991 |
Van Tol HH, Bunzow JR, Guan HC, Sunahara RK, Seeman P, Niznik HB, Civelli O. Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine. Nature. 350: 610-4. PMID 1840645 DOI: 10.1038/350610A0 |
0.391 |
|
| 1991 |
Sunahara RK, Guan HC, O'Dowd BF, Seeman P, Laurier LG, Ng G, George SR, Torchia J, Van Tol HHM, Niznik HB. Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1 Nature. 350: 614-619. PMID 1826762 DOI: 10.1038/350614A0 |
0.412 |
|
| 1991 |
Mengod G, Vilaró MT, Niznik HB, Sunahara RK, Seeman P, O'Dowd BF, Palacios JM. Visualization of a dopamine D1 receptor mRNA in human and rat brain. Brain Research. Molecular Brain Research. 10: 185-91. PMID 1649371 DOI: 10.1016/0169-328X(91)90110-J |
0.333 |
|
| 1990 |
Sunahara RK, Niznik HB, Weiner DM, Stormann TM, Brann MR, Kennedy JL, Gelernter JE, Rozmahel R, Yang YL, Israel Y. Human dopamine D1 receptor encoded by an intronless gene on chromosome 5. Nature. 347: 80-3. PMID 1975640 DOI: 10.1038/347080A0 |
0.435 |
|
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