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David A. Fell, PhD - Publications

Affiliations: 
Biological and Medical Sciences  Oxford Brookes University, Oxford, England, United Kingdom 
Area:
Systems Biology
Website:
http://www.brookes.ac.uk/profiles/staff/david_fell

84 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Woodfield HK, Fenyk S, Wallington E, Bates RE, Brown A, Guschina IA, Marillia EF, Taylor DC, Fell D, Harwood JL, Fawcett T. Increase in lysophosphatidate acyltransferase activity in oilseed rape (Brassica napus) increases seed triacylglycerol content despite its low intrinsic flux control coefficient. The New Phytologist. PMID 31400160 DOI: 10.1111/Nph.16100  0.37
2018 Huma B, Kundu S, Poolman MG, Kruger NJ, Fell DA. Stoichiometric analysis of the energetics and metabolic impact of photorespiration in C3 plants. The Plant Journal : For Cell and Molecular Biology. PMID 30257035 DOI: 10.1111/Tpj.14105  0.391
2018 Fell DA. Genotype to phenotype mapping still needs under-pinning by research in metabolism and enzymology. Bioscience Reports. PMID 29848765 DOI: 10.1042/Bsr20180520  0.364
2018 Fatma Z, Hartman H, Poolman MG, Fell DA, Srivastava S, Shakeel T, Yazdani SS. Model-assisted metabolic engineering of Escherichia coli for long chain alkane and alcohol production. Metabolic Engineering. PMID 29408291 DOI: 10.1016/J.Ymben.2018.01.002  0.324
2017 Pentjuss A, Stalidzans E, Liepins J, Kokina A, Martynova J, Zikmanis P, Mozga I, Scherbaka R, Hartman H, Poolman MG, Fell DA, Vigants A. Model-based biotechnological potential analysis of Kluyveromyces marxianus central metabolism. Journal of Industrial Microbiology & Biotechnology. PMID 28444480 DOI: 10.1007/S10295-017-1946-8  0.372
2017 Ahmad A, Hartman HB, Krishnakumar S, Fell DA, Poolman MG, Srivastava S. A Genome Scale Model of Geobacillus thermoglucosidasius (C56-YS93) reveals its biotechnological potential on rice straw hydrolysate. Journal of Biotechnology. PMID 28385593 DOI: 10.1016/J.Jbiotec.2017.03.031  0.352
2015 Singh D, Carlson R, Fell D, Poolman M. Modelling metabolism of the diatom Phaeodactylum tricornutum. Biochemical Society Transactions. 43: 1182-6. PMID 26614658 DOI: 10.1042/Bst20150152  0.419
2014 Poolman MG, Kundu S, Shaw R, Fell DA. Metabolic trade-offs between biomass synthesis and photosynthate export at different light intensities in a genome-scale metabolic model of rice. Frontiers in Plant Science. 5: 656. PMID 25506349 DOI: 10.3389/Fpls.2014.00656  0.386
2014 Hartman HB, Fell DA, Rossell S, Jensen PR, Woodward MJ, Thorndahl L, Jelsbak L, Olsen JE, Raghunathan A, Daefler S, Poolman MG. Identification of potential drug targets in Salmonella enterica sv. Typhimurium using metabolic modelling and experimental validation. Microbiology (Reading, England). 160: 1252-66. PMID 24777662 DOI: 10.1099/Mic.0.076091-0  0.356
2014 Cheung CY, Poolman MG, Fell DA, Ratcliffe RG, Sweetlove LJ. A Diel Flux Balance Model Captures Interactions between Light and Dark Metabolism during Day-Night Cycles in C3 and Crassulacean Acid Metabolism Leaves. Plant Physiology. 165: 917-929. PMID 24596328 DOI: 10.1104/Pp.113.234468  0.405
2014 Kalnenieks U, Pentjuss A, Rutkis R, Stalidzans E, Fell DA. Modeling of Zymomonas mobilis central metabolism for novel metabolic engineering strategies. Frontiers in Microbiology. 5: 42. PMID 24550906 DOI: 10.3389/Fmicb.2014.00042  0.435
2013 Rutkis R, Kalnenieks U, Stalidzans E, Fell DA. Kinetic modelling of the Zymomonas mobilis Entner-Doudoroff pathway: insights into control and functionality. Microbiology (Reading, England). 159: 2674-89. PMID 24085837 DOI: 10.1099/Mic.0.071340-0  0.44
2013 Cheung CY, Williams TC, Poolman MG, Fell DA, Ratcliffe RG, Sweetlove LJ. A method for accounting for maintenance costs in flux balance analysis improves the prediction of plant cell metabolic phenotypes under stress conditions. The Plant Journal : For Cell and Molecular Biology. 75: 1050-61. PMID 23738527 DOI: 10.1111/Tpj.12252  0.387
2013 Poolman MG, Kundu S, Shaw R, Fell DA. Responses to light intensity in a genome-scale model of rice metabolism. Plant Physiology. 162: 1060-72. PMID 23640755 DOI: 10.1104/Pp.113.216762  0.377
2013 Pentjuss A, Odzina I, Kostromins A, Fell DA, Stalidzans E, Kalnenieks U. Biotechnological potential of respiring Zymomonas mobilis: a stoichiometric analysis of its central metabolism. Journal of Biotechnology. 165: 1-10. PMID 23471074 DOI: 10.1016/J.Jbiotec.2013.02.014  0.407
2010 Fell DA, Poolman MG, Gevorgyan A. Building and analysing genome-scale metabolic models. Biochemical Society Transactions. 38: 1197-201. PMID 20863283 DOI: 10.1042/Bst0381197  0.334
2010 Fell DA. Evolution of central carbon metabolism. Molecular Cell. 39: 663-4. PMID 20832718 DOI: 10.1016/J.Molcel.2010.08.034  0.328
2010 Williams TC, Poolman MG, Howden AJ, Schwarzlander M, Fell DA, Ratcliffe RG, Sweetlove LJ. A genome-scale metabolic model accurately predicts fluxes in central carbon metabolism under stress conditions. Plant Physiology. 154: 311-23. PMID 20605915 DOI: 10.1104/Pp.110.158535  0.404
2009 Poolman MG, Miguet L, Sweetlove LJ, Fell DA. A genome-scale metabolic model of Arabidopsis and some of its properties. Plant Physiology. 151: 1570-81. PMID 19755544 DOI: 10.1104/Pp.109.141267  0.403
2009 de Figueiredo LF, Schuster S, Kaleta C, Fell DA. Can sugars be produced from fatty acids? A test case for pathway analysis tools. Bioinformatics (Oxford, England). 25: 152-8. PMID 19117076  0.331
2008 de Figueiredo LF, Schuster S, Kaleta C, Fell DA. Can sugars be produced from fatty acids? A test case for pathway analysis tools. Bioinformatics (Oxford, England). 24: 2615-21. PMID 18806269 DOI: 10.1093/Bioinformatics/Btn500  0.436
2008 Gevorgyan A, Poolman MG, Fell DA. Detection of stoichiometric inconsistencies in biomolecular models. Bioinformatics (Oxford, England). 24: 2245-51. PMID 18697772 DOI: 10.1093/Bioinformatics/Btn425  0.375
2008 Schuster S, Pfeiffer T, Fell DA. Is maximization of molar yield in metabolic networks favoured by evolution? Journal of Theoretical Biology. 252: 497-504. PMID 18249414 DOI: 10.1016/J.Jtbi.2007.12.008  0.412
2008 Sweetlove LJ, Fell D, Fernie AR. Getting to grips with the plant metabolic network. The Biochemical Journal. 409: 27-41. PMID 18062772 DOI: 10.1042/Bj20071115  0.369
2007 Poolman MG, Sebu C, Pidcock MK, Fell DA. Modular decomposition of metabolic systems via null-space analysis. Journal of Theoretical Biology. 249: 691-705. PMID 17949756 DOI: 10.1016/J.Jtbi.2007.08.005  0.381
2007 Fell DA. How can we understand metabolism? Systems Biology. 87-101. DOI: 10.1016/B978-044452085-2/50006-1  0.302
2005 Vogt AM, Elsässer A, Pott-Beckert A, Ackermann C, Vetter SY, Yildiz M, Schoels W, Fell DA, Katus HA, Kübler W. Myocardial energy metabolism in ischemic preconditioning and cardioplegia: a metabolic control analysis. Molecular and Cellular Biochemistry. 278: 223-32. PMID 16180108 DOI: 10.1007/S11010-005-7576-X  0.342
2005 Fell DA. Enzymes, metabolites and fluxes. Journal of Experimental Botany. 56: 267-72. PMID 15545297 DOI: 10.1093/Jxb/Eri011  0.45
2005 Fell DA. Metabolic Control Analysis for the NMR Spectroscopist Metabolomics by in Vivo Nmr. 31-44. DOI: 10.1002/0470011505.ch3  0.313
2004 Poolman MG, Venkatesh KV, Pidcock MK, Fell DA. A method for the determination of flux in elementary modes, and its application to Lactobacillus rhamnosus. Biotechnology and Bioengineering. 88: 601-12. PMID 15470705 DOI: 10.1002/Bit.20273  0.347
2004 Poolman MG, Assmus HE, Fell DA. Applications of metabolic modelling to plant metabolism. Journal of Experimental Botany. 55: 1177-86. PMID 15073223 DOI: 10.1093/Jxb/Erh090  0.422
2004 Schafer JR, Fell DA, Rothman D, Shulman RG. Protein phosphorylation can regulate metabolite concentrations rather than control flux: the example of glycogen synthase. Proceedings of the National Academy of Sciences of the United States of America. 101: 1485-90. PMID 14745035 DOI: 10.1073/Pnas.0307299101  0.306
2003 Chassagnole C, Quentin E, Fell DA, de Atauri P, Mazat JP. Dynamic simulation of pollutant effects on the threonine pathway in Escherichia coli. Comptes Rendus Biologies. 326: 501-8. PMID 12886877 DOI: 10.1016/S1631-0691(03)00098-2  0.42
2003 Papin JA, Price ND, Wiback SJ, Fell DA, Palsson BO. Metabolic pathways in the post-genome era. Trends in Biochemical Sciences. 28: 250-8. PMID 12765837 DOI: 10.1016/S0968-0004(03)00064-1  0.38
2003 Poolman MG, Fell DA, Raines CA. Elementary modes analysis of photosynthate metabolism in the chloroplast stroma. European Journal of Biochemistry / Febs. 270: 430-9. PMID 12542693 DOI: 10.1046/J.1432-1033.2003.03390.X  0.415
2002 Vauclare P, Kopriva S, Fell D, Suter M, Sticher L, von Ballmoos P, Krähenbühl U, den Camp RO, Brunold C. Flux control of sulphate assimilation in Arabidopsis thaliana: adenosine 5'-phosphosulphate reductase is more susceptible than ATP sulphurylase to negative control by thiols. The Plant Journal : For Cell and Molecular Biology. 31: 729-40. PMID 12220264 DOI: 10.1046/J.1365-313X.2002.01391.X  0.343
2002 Schuster S, Hilgetag C, Woods JH, Fell DA. Reaction routes in biochemical reaction systems: algebraic properties, validated calculation procedure and example from nucleotide metabolism. Journal of Mathematical Biology. 45: 153-81. PMID 12181603 DOI: 10.1007/S002850200143  0.348
2002 Carlson R, Fell D, Srienc F. Metabolic pathway analysis of a recombinant yeast for rational strain development. Biotechnology and Bioengineering. 79: 121-34. PMID 12115428 DOI: 10.1002/Bit.10305  0.366
2002 Vogt AM, Nef H, Schaper J, Poolman M, Fell DA, Kübler W, Elsässer A. Metabolic control analysis of anaerobic glycolysis in human hibernating myocardium replaces traditional concepts of flux control. Febs Letters. 517: 245-50. PMID 12062446 DOI: 10.1016/S0014-5793(02)02632-7  0.433
2002 de Atauri P, Fell DA, Chassagnole C, Magret D, Mazat JP, Cascante M. Dependence of control coefficient distribution on the boundaries of a metabolic system: a generalized analysis of the effects of additional input and output reactions to a linear pathway. Journal of Theoretical Biology. 215: 239-51. PMID 12051977 DOI: 10.1006/Jtbi.2001.2492  0.471
2002 Vogt AM, Poolman M, Ackermann C, Yildiz M, Schoels W, Fell DA, Kubler W. Regulation of glycolytic flux in ischemic preconditioning. A study employing metabolic control analysis. The Journal of Biological Chemistry. 277: 24411-9. PMID 12006584 DOI: 10.1074/Jbc.M201138200  0.405
2001 Wagner A, Fell DA. The small world inside large metabolic networks. Proceedings. Biological Sciences / the Royal Society. 268: 1803-10. PMID 11522199 DOI: 10.1098/Rspb.2001.1711  0.372
2001 Chassagnole C, Fell DA, Raïs B, Kudla B, Mazat JP. Control of the threonine-synthesis pathway in Escherichia coli: a theoretical and experimental approach. The Biochemical Journal. 356: 433-44. PMID 11368770 DOI: 10.1042/0264-6021:3560433  0.434
2001 Raïs B, Chassagnole C, Letellier T, Fell DA, Mazat JP. Threonine synthesis from aspartate in Escherichia coli cell-free extracts: pathway dynamics. The Biochemical Journal. 356: 425-32. PMID 11368769 DOI: 10.1042/Bj3560425  0.349
2001 Chassagnole C, Raïs B, Quentin E, Fell DA, Mazat JP. An integrated study of threonine-pathway enzyme kinetics in Escherichia coli. The Biochemical Journal. 356: 415-23. PMID 11368768 DOI: 10.1042/Bj3560415  0.395
2001 Poolman MG, Olçer H, Lloyd JC, Raines CA, Fell DA. Computer modelling and experimental evidence for two steady states in the photosynthetic Calvin cycle. European Journal of Biochemistry / Febs. 268: 2810-6. PMID 11358496 DOI: 10.1046/J.1432-1327.2001.02153.X  0.354
2001 GLEISS PM, STADLER PF, WAGNER A, FELL DA. RELEVANT CYCLES IN CHEMICAL REACTION NETWORKS Advances in Complex Systems. 4: 207-226. DOI: 10.1142/S0219525901000140  0.339
2000 Fell DA, Wagner A. The small world of metabolism. Nature Biotechnology. 18: 1121-2. PMID 11062388 DOI: 10.1038/81025  0.402
2000 Poolman MG, Fell DA, Thomas S. Modelling photosynthesis and its control. Journal of Experimental Botany. 51: 319-28. PMID 10938839 DOI: 10.1093/Jexbot/51.Suppl_1.319  0.402
2000 Fell DA. Signal transduction and the control of expression of enzyme activity. Advances in Enzyme Regulation. 40: 35-46. PMID 10828344 DOI: 10.1016/S0065-2571(99)00029-1  0.309
2000 Schuster S, Fell DA, Dandekar T. A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networks. Nature Biotechnology. 18: 326-32. PMID 10700151 DOI: 10.1038/73786  0.436
2000 Poolman MG, Fell DA. Scrumpi: A metabolic model control language Biochemical Society Transactions. 28: A196-A196. DOI: 10.1042/Bst028A196B  0.368
1999 Schuster S, Dandekar T, Fell DA. Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineering. Trends in Biotechnology. 17: 53-60. PMID 10087604 DOI: 10.1016/S0167-7799(98)01290-6  0.416
1999 Thomas S, Poolman MG, Fell DA. Computer simulation and evolution strategies in the study of rat heart glucose metabolism Biochemical Society Transactions. 27: A48-A48. DOI: 10.1042/Bst027A048B  0.32
1998 Fell DA. Increasing the flux in metabolic pathways: A metabolic control analysis perspective Biotechnology and Bioengineering. 58: 121-4. PMID 10191380 DOI: 10.1002/(Sici)1097-0290(19980420)58:2/3<121::Aid-Bit2>3.0.Co;2-N  0.48
1998 Thomas S, Fell DA. A control analysis exploration of the role of ATP utilisation in glycolytic-flux control and glycolytic-metabolite-concentration regulation. European Journal of Biochemistry / Febs. 258: 956-67. PMID 9990313 DOI: 10.1046/J.1432-1327.1998.2580956.X  0.447
1998 Thomas S, Fell DA. The role of multiple enzyme activation in metabolic flux control. Advances in Enzyme Regulation. 38: 65-85. PMID 9762347 DOI: 10.1016/S0065-2571(97)00012-5  0.46
1997 Thomas S, Mooney PJ, Burrell MM, Fell DA. Metabolic Control Analysis of glycolysis in tuber tissue of potato (Solanum tuberosum): explanation for the low control coefficient of phosphofructokinase over respiratory flux. The Biochemical Journal. 322: 119-27. PMID 9078251 DOI: 10.1042/Bj3220119  0.45
1997 Thomas S, Mooney PJ, Burrell MM, Fell DA. Finite change analysis of glycolytic intermediates in tuber tissue of lines of transgenic potato (Solanum tuberosum) overexpressing phosphofructokinase. The Biochemical Journal. 322: 111-7. PMID 9078250 DOI: 10.1042/Bj3220111  0.373
1996 Veech RL, Fell DA. Distribution control of metabolic flux. Cell Biochemistry and Function. 14: 229-36. PMID 8952041 DOI: 10.1002/Cbf.697  0.413
1996 Thomas S, Fell DA. Design of metabolic control for large flux changes. Journal of Theoretical Biology. 182: 285-98. PMID 8944160 DOI: 10.1006/Jtbi.1996.0166  0.472
1995 Fell DA, Thomas S. Physiological control of metabolic flux: the requirement for multisite modulation. The Biochemical Journal. 311: 35-9. PMID 7575476 DOI: 10.1042/Bj3110035  0.479
1994 Thomas S, Fell DA. Metabolic control analysis: Sensitivity of control coefficients to experimentally determined variables Journal of Theoretical Biology. 167: 175-200. DOI: 10.1006/Jtbi.1994.1063  0.368
1993 Thomas S, Fell DA. A computer program for the algebraic determination of control coefficients in Metabolic Control Analysis. The Biochemical Journal. 292: 351-60. PMID 8503870 DOI: 10.1042/Bj2920351  0.395
1993 Fell DA. The analysis of flux in substrate cycles. Biochemical Society Transactions. 21: 257S. PMID 8224409 DOI: 10.1042/Bst021257S  0.378
1992 Fell DA. Metabolic control analysis: a survey of its theoretical and experimental development. The Biochemical Journal. 286: 313-30. PMID 1530563 DOI: 10.1042/Bj2860313  0.413
1991 Sauro HM, Fell DA. SCAMP: A metabolic simulator and control analysis program Mathematical and Computer Modelling. 15: 15-28. DOI: 10.1016/0895-7177(91)90038-9  0.636
1990 Fell DA, Sauro HM. Metabolic control analysis. The effects of high enzyme concentrations. European Journal of Biochemistry / Febs. 192: 183-7. PMID 2401290 DOI: 10.1111/J.1432-1033.1990.Tb19212.X  0.645
1990 Small JR, Fell DA. Covalent modification and metabolic control analysis. Modification to the theorems and their application to metabolic systems containing covalently modifiable enzymes. European Journal of Biochemistry / Febs. 191: 405-11. PMID 2384088 DOI: 10.1111/J.1432-1033.1990.Tb19136.X  0.461
1990 Snell K, Fell DA. Metabolic control analysis of mammalian serine metabolism. Advances in Enzyme Regulation. 30: 13-32. PMID 2119548 DOI: 10.1016/0065-2571(90)90006-N  0.47
1990 Fell DA, Sauro HM. Metabolic control analysis by computer: progress and prospects. Biomedica Biochimica Acta. 49: 811-6. PMID 2082924  0.605
1989 Small JR, Fell DA. The matrix method of metabolic control analysis: its validity for complex pathway structures. Journal of Theoretical Biology. 136: 181-97. PMID 2779266 DOI: 10.1016/S0022-5193(89)80225-5  0.44
1988 Fell DA, Snell K. Control analysis of mammalian serine biosynthesis. Feedback inhibition on the final step. The Biochemical Journal. 256: 97-101. PMID 2851987 DOI: 10.1042/Bj2560097  0.455
1987 Sauro HM, Small JR, Fell DA. Metabolic control and its analysis. Extensions to the theory and matrix method. European Journal of Biochemistry / Febs. 165: 215-21. PMID 3569295 DOI: 10.1111/J.1432-1033.1987.Tb11214.X  0.643
1987 SMALL JR, FELL DA. Responses of metabolic systems: application of control analysis to yeast glycolysis Biochemical Society Transactions. 15: 238-238. DOI: 10.1042/Bst0150238  0.396
1987 SAURO HM, FELL DA. The role of co-operativity in metabolism Biochemical Society Transactions. 15: 234-235. DOI: 10.1042/Bst0150234  0.585
1986 Fell DA, Small JR. Fat synthesis in adipose tissue. An examination of stoichiometric constraints. The Biochemical Journal. 238: 781-6. PMID 3800960 DOI: 10.1042/Bj2380781  0.337
1986 FELL DA, SAURO HM. Non-equilibrium/equilibrium reactions: which controls? Biochemical Society Transactions. 14: 624-625. DOI: 10.1042/Bst0140624  0.545
1986 FELL DA, SMALL JR. Theoretical aspects of covalent modification in metabolic control Biochemical Society Transactions. 14: 623-624. DOI: 10.1042/Bst0140623A  0.439
1985 Fell DA, Sauro HM. Metabolic control and its analysis. Additional relationships between elasticities and control coefficients. European Journal of Biochemistry / Febs. 148: 555-61. PMID 3996393 DOI: 10.1111/J.1432-1033.1985.Tb08876.X  0.659
1985 FELL DA, SAURO HM. Substrate cycles: do they really cause amplification? Biochemical Society Transactions. 13: 762-763. DOI: 10.1042/Bst0130762  0.544
1984 Fell DA. Phosphofructokinase and glycolytic flux Trends in Biochemical Sciences. 9: 515-516. DOI: 10.1016/0968-0004(84)90277-9  0.321
1974 Fell DA, Liddle PF, Peacocke AR, Dwek RA. The preparation and properties of pyruvate kinase from yeast. The Biochemical Journal. 139: 665-75. PMID 4369339 DOI: 10.1042/Bj1390665  0.557
1972 Fell DA, Peacocke AR, Dwek RA. Proton-relaxation-enhancement studies on the binding to yeast pyruvate kinase of a substrate and effectors. European Journal of Biochemistry / Febs. 29: 128-33. PMID 4343297 DOI: 10.1111/J.1432-1033.1972.Tb01966.X  0.555
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