Janet D. Sparks - Publications

Affiliations: 
University of Rochester, Rochester, NY 
Area:
Pathology, Cell Biology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sparks RP, Guida WC, Sowden MP, Jenkins JL, Starr ML, Fratti RA, Sparks CE, Sparks JD. Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells. Biochemical and Biophysical Research Communications. PMID 27495870 DOI: 10.1016/J.Bbrc.2016.07.096  0.52
2015 Sparks CE, Sparks RP, Sparks JD. The enigmatic role of sortilin in lipoprotein metabolism. Current Opinion in Lipidology. 26: 598-600. PMID 26780014 DOI: 10.1097/Mol.0000000000000244  0.434
2015 Sparks JD, Magra AL, Chamberlain JM, O'Dell C, Sparks CE. Insulin dependent apolipoprotein B degradation and phosphatidylinositide 3-kinase activation with microsomal translocation are restored in McArdle RH7777 cells following serum deprivation. Biochemical and Biophysical Research Communications. PMID 26616056 DOI: 10.1016/J.Bbrc.2015.11.068  0.49
2014 Yu IC, Lin HY, Sparks JD, Yeh S, Chang C. Androgen receptor roles in insulin resistance and obesity in males: the linkage of androgen-deprivation therapy to metabolic syndrome. Diabetes. 63: 3180-8. PMID 25249645 DOI: 10.2337/Db13-1505  0.303
2014 Greene MW, Burrington CM, Lynch DT, Davenport SK, Johnson AK, Horsman MJ, Chowdhry S, Zhang J, Sparks JD, Tirrell PC. Lipid metabolism, oxidative stress and cell death are regulated by PKC delta in a dietary model of nonalcoholic steatohepatitis. Plos One. 9: e85848. PMID 24454937 DOI: 10.1371/Journal.Pone.0085848  0.326
2013 Sparks CE, Sparks JD. Hepatic postprandial transition and very low-density lipoprotein biogenesis. Current Opinion in Lipidology. 24: 450-2. PMID 24005219 DOI: 10.1097/Mol.0B013E3283654Ed0  0.317
2013 Sparks JD, O'Dell C, Chamberlain JM, Sparks CE. Insulin-dependent apolipoprotein B degradation is mediated by autophagy and involves class I and class III phosphatidylinositide 3-kinases. Biochemical and Biophysical Research Communications. 435: 616-20. PMID 23685141 DOI: 10.1016/J.Bbrc.2013.05.029  0.534
2013 Chamberlain JM, O'Dell C, Sparks CE, Sparks JD. Insulin suppression of apolipoprotein B in McArdle RH7777 cells involves increased sortilin 1 interaction and lysosomal targeting. Biochemical and Biophysical Research Communications. 430: 66-71. PMID 23159624 DOI: 10.1016/J.Bbrc.2012.11.022  0.54
2013 Yu IC, Lin HY, Liu NC, Sparks JD, Yeh S, Fang LY, Chen L, Chang C. Neuronal androgen receptor regulates insulin sensitivity via suppression of hypothalamic NF-κB-mediated PTP1B expression. Diabetes. 62: 411-23. PMID 23139353 DOI: 10.2337/Db12-0135  0.444
2012 Sparks CE, Sparks JD. Hepatic steatosis and VLDL hypersecretion. Current Opinion in Lipidology. 23: 395-7. PMID 22801389 DOI: 10.1097/Mol.0B013E3283555Afa  0.312
2012 Sparks JD, Sparks CE, Adeli K. Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2104-12. PMID 22796579 DOI: 10.1161/Atvbaha.111.241463  0.46
2011 Kim E, Liu NC, Yu IC, Lin HY, Lee YF, Sparks JD, Chen LM, Chang C. Metformin inhibits nuclear receptor TR4-mediated hepatic stearoyl-CoA desaturase 1 gene expression with altered insulin sensitivity. Diabetes. 60: 1493-503. PMID 21478464 DOI: 10.2337/Db10-0393  0.417
2011 Sparks JD, Chamberlain JM, O'Dell C, Khatun I, Hussain MM, Sparks CE. Acute suppression of apo B secretion by insulin occurs independently of MTP. Biochemical and Biophysical Research Communications. 406: 252-6. PMID 21316344 DOI: 10.1016/J.Bbrc.2011.02.028  0.561
2011 Nigro P, Satoh K, O'Dell MR, Soe NN, Cui Z, Mohan A, Abe J, Alexis JD, Sparks JD, Berk BC. Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice. The Journal of Experimental Medicine. 208: 53-66. PMID 21173104 DOI: 10.1084/Jem.20101174  0.313
2011 Meex SJ, Andreo U, Sparks JD, Fisher EA. Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion? Journal of Lipid Research. 52: 152-8. PMID 20956548 DOI: 10.1194/Jlr.D008888  0.399
2010 Sparks JD, Cianci J, Jokinen J, Chen LS, Sparks CE. Interleukin-6 mediates hepatic hypersecretion of apolipoprotein B. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G980-9. PMID 20651008 DOI: 10.1152/Ajpgi.00080.2010  0.43
2010 Galloway CA, Ashton J, Sparks JD, Mooney RA, Smith HC. Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes. Biochimica Et Biophysica Acta. 1802: 976-85. PMID 20541607 DOI: 10.1016/J.Bbadis.2010.06.003  0.46
2009 Sparks JD, Dong HH. FoxO1 and hepatic lipid metabolism. Current Opinion in Lipidology. 20: 217-226. PMID 21037971 DOI: 10.1097/Mol.0B013E32832B3F4C  0.454
2009 Caviglia JM, Sparks JD, Toraskar N, Brinker AM, Yin TC, Dixon JL, Brasaemle DL. ABHD5/CGI-58 facilitates the assembly and secretion of apolipoprotein B lipoproteins by McA RH7777 rat hepatoma cells. Biochimica Et Biophysica Acta. 1791: 198-205. PMID 19211039 DOI: 10.1016/J.Bbalip.2008.12.018  0.45
2008 Sparks JD, Sparks CE. Overindulgence and metabolic syndrome: is FoxO1 a missing link? The Journal of Clinical Investigation. 118: 2012-5. PMID 18497882 DOI: 10.1172/Jci35693  0.423
2008 Lin HY, Yu IC, Wang RS, Chen YT, Liu NC, Altuwaijri S, Hsu CL, Ma WL, Jokinen J, Sparks JD, Yeh S, Chang C. Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor. Hepatology (Baltimore, Md.). 47: 1924-35. PMID 18449947 DOI: 10.1002/Hep.22252  0.418
2008 Yu IC, Lin HY, Liu NC, Wang RS, Sparks JD, Yeh S, Chang C. Hyperleptinemia without obesity in male mice lacking androgen receptor in adipose tissue. Endocrinology. 149: 2361-8. PMID 18276764 DOI: 10.1210/En.2007-0516  0.347
2006 Nieman KM, Hartz CS, Szegedi SS, Garrow TA, Sparks JD, Schalinske KL. Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats. American Journal of Physiology. Endocrinology and Metabolism. 291: E1235-42. PMID 16835399 DOI: 10.1152/Ajpendo.00237.2006  0.33
2006 Chirieac DV, Davidson NO, Sparks CE, Sparks JD. PI3-kinase activity modulates apo B available for hepatic VLDL production in apobec-1-/- mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G382-8. PMID 16798720 DOI: 10.1152/Ajpgi.00472.2005  0.474
2006 Sparks JD, Collins HL, Chirieac DV, Cianci J, Jokinen J, Sowden MP, Galloway CA, Sparks CE. Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase. The Biochemical Journal. 395: 363-71. PMID 16396637 DOI: 10.1042/Bj20051966  0.679
2004 Chirieac DV, Collins HL, Cianci J, Sparks JD, Sparks CE. Altered triglyceride-rich lipoprotein production in Zucker diabetic fatty rats. American Journal of Physiology. Endocrinology and Metabolism. 287: E42-9. PMID 14970003 DOI: 10.1152/Ajpendo.00297.2003  0.668
2004 Au CS, Wagner A, Chong T, Qiu W, Sparks JD, Adeli K. Insulin regulates hepatic apolipoprotein B production independent of the mass or activity of Akt1/PKBalpha. Metabolism: Clinical and Experimental. 53: 228-35. PMID 14767876 DOI: 10.1016/J.Metabol.2003.09.011  0.481
2004 Patel NA, Apostolatos HS, Mebert K, Chalfant CE, Watson JE, Pillay TS, Sparks J, Cooper DR. Insulin regulates protein kinase CbetaII alternative splicing in multiple target tissues: development of a hormonally responsive heterologous minigene. Molecular Endocrinology (Baltimore, Md.). 18: 899-911. PMID 14752056 DOI: 10.1210/Me.2003-0391  0.407
2002 Chirieac DV, Cianci J, Collins HL, Sparks JD, Sparks CE. Insulin suppression of VLDL apo B secretion is not mediated by the LDL receptor. Biochemical and Biophysical Research Communications. 297: 134-7. PMID 12220520 DOI: 10.1016/S0006-291X(02)02140-X  0.707
2001 Fisher EA, Pan M, Chen X, Wu X, Wang H, Jamil H, Sparks JD, Williams KJ. The triple threat to nascent apolipoprotein B. Evidence for multiple, distinct degradative pathways. The Journal of Biological Chemistry. 276: 27855-63. PMID 11285257 DOI: 10.1074/Jbc.M008885200  0.389
2000 Sparks JD, Shaw WN, Corsetti JP, Bolognino M, Pesek JF, Sparks CE. Insulin-treated Zucker diabetic fatty rats retain the hypertriglyceridemia associated with obesity. Metabolism: Clinical and Experimental. 49: 1424-30. PMID 11092505 DOI: 10.1053/Meta.2000.17736  0.484
2000 Chirieac DV, Chirieac LR, Corsetti JP, Cianci J, Sparks CE, Sparks JD. Glucose-stimulated insulin secretion suppresses hepatic triglyceride-rich lipoprotein and apoB production. American Journal of Physiology. Endocrinology and Metabolism. 279: E1003-11. PMID 11052954 DOI: 10.1152/Ajpendo.2000.279.5.E1003  0.49
2000 Collins HL, Sparks CE, Sparks JD. B48 is preferentially translated over B100 in cells with increased endogenous apo B mRNA. Biochemical and Biophysical Research Communications. 273: 1156-60. PMID 10891388 DOI: 10.1006/Bbrc.2000.3074  0.668
2000 Corsetti JP, Sparks JD, Peterson RG, Smith RL, Sparks CE. Effect of dietary fat on the development of non-insulin dependent diabetes mellitus in obese Zucker diabetic fatty male and female rats. Atherosclerosis. 148: 231-41. PMID 10657558 DOI: 10.1016/S0021-9150(99)00265-8  0.301
2000 Sparks J, Wagner A, Phung T, Sparks C. Insulin, PI 3-Kinase and apolipoprotein B biogenesis Atherosclerosis. 151: 238. DOI: 10.1016/S0021-9150(00)81080-1  0.448
1999 Sowden MP, Collins HL, Smith HC, Garrow TA, Sparks JD, Sparks CE. Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase. The Biochemical Journal. 341: 639-45. PMID 10417327 DOI: 10.1042/Bj3410639  0.662
1998 Van Mater D, Sowden MP, Cianci J, Sparks JD, Sparks CE, Ballatori N, Smith HC. Ethanol increases apolipoprotein B mRNA editing in rat primary hepatocytes and McArdle cells Biochemical and Biophysical Research Communications. 252: 334-339. PMID 9826530 DOI: 10.1006/Bbrc.1998.9647  0.351
1998 Sparks JD, Phung TL, Bolognino M, Cianci J, Khurana R, Peterson RG, Sowden MP, Corsetti JP, Sparks CE. Lipoprotein alterations in 10- and 20-week-old Zucker diabetic fatty rats: hyperinsulinemic versus insulinopenic hyperglycemia. Metabolism: Clinical and Experimental. 47: 1315-24. PMID 9826206 DOI: 10.1016/S0026-0495(98)90298-0  0.367
1998 Phung TL, Roncone A, Jensen KL, Sparks CE, Sparks JD. Phosphoinositide 3-kinase activity is necessary for insulin-dependent inhibition of apolipoprotein B secretion by rat hepatocytes and localizes to the endoplasmic reticulum. The Journal of Biological Chemistry. 272: 30693-702. PMID 9388205 DOI: 10.1074/Jbc.272.49.30693  0.41
1997 Phung TL, Mooney RA, Kulas DT, Sparks CE, Sparks JD. Suppression of the protein tyrosine phosphatase LAR reduces apolipoprotein B secretion by McA-RH7777 rat hepatoma cells Biochemical and Biophysical Research Communications. 237: 367-371. PMID 9268718 DOI: 10.1006/Bbrc.1997.7142  0.566
1997 Sparks JD, Collins HL, Sabio I, Sowden MP, Smith HC, Cianci J, Sparks CE. Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells. Biochimica Et Biophysica Acta. 1347: 51-61. PMID 9233686 DOI: 10.1016/S0005-2760(97)00050-7  0.679
1996 Phung TL, Sowden MP, Sparks JD, Sparks CE, Smith HC. Regulation of hepatic apolipoprotein B RNA editing in the genetically obese Zucker rat. Metabolism: Clinical and Experimental. 45: 1056-8. PMID 8781289 DOI: 10.1016/S0026-0495(96)90001-3  0.41
1996 Sparks JD, Phung TL, Bolognino M, Sparks CE. Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes. The Biochemical Journal. 567-74. PMID 8573094 DOI: 10.1042/Bj3130567  0.535
1994 Björnsson OG, Sparks JD, Sparks CE, Gibbons GF. Regulation of VLDL secretion in primary culture of rat hepatocytes: involvement of cAMP and cAMP-dependent protein kinases. European Journal of Clinical Investigation. 24: 137-48. PMID 8206083 DOI: 10.1111/J.1365-2362.1994.Tb00979.X  0.399
1994 Sparks JD, Corsetti JP, Sparks CE. Liver regrowth and apolipoprotein B secretion by rat hepatocytes following partial hepatectomy. Metabolism: Clinical and Experimental. 43: 681-90. PMID 8201956 DOI: 10.1016/0026-0495(94)90115-5  0.514
1994 Sparks JD, Sparks CE. Obese Zucker (fa/fa) rats are resistant to insulin's inhibitory effect on hepatic apo B secretion Biochemical and Biophysical Research Communications. 205: 417-422. PMID 7999057 DOI: 10.1006/Bbrc.1994.2681  0.503
1994 Sparks JD, Sparks CE. Insulin regulation of triacylglycerol-rich lipoprotein synthesis and secretion Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 1215: 9-32. PMID 7948013 DOI: 10.1016/0005-2760(94)90088-4  0.482
1993 Corsetti JP, Sparks JD, Sikora B, Sparks CE. Cellular heterogeneity in binding and uptake of low-density lipoprotein in primary rat hepatocytes. Hepatology (Baltimore, Md.). 17: 645-50. PMID 8477969 DOI: 10.1002/Hep.1840170419  0.358
1993 Sparks JD, Sparks CE. Hormonal regulation of lipoprotein assembly and secretion Current Opinion in Lipidology. 4: 177-186. DOI: 10.1097/00041433-199306000-00002  0.312
1992 Sparks JD, Zolfaghari R, Sparks CE, Smith HC, Fisher EA. Impaired hepatic apolipoprotein B and E translation in streptozotocin diabetic rats. The Journal of Clinical Investigation. 89: 1418-30. PMID 1533230 DOI: 10.1172/Jci115731  0.488
1992 Gibbons GF, Bartlett SM, Sparks CE, Sparks JD. Extracellular fatty acids are not utilized directly for the synthesis of very-low-density lipoprotein in primary cultures of rat hepatocytes. The Biochemical Journal. 749-53. PMID 1445239 DOI: 10.1042/Bj2870749  0.35
1992 Corsetti JP, Way BA, Sparks CE, Sparks JD. Immunolocalization, quantitation and cellular heterogeneity of apolipoprotein B in rat hepatocytes. Hepatology (Baltimore, Md.). 15: 1117-24. PMID 1375579 DOI: 10.1002/Hep.1840150624  0.455
1992 Björnsson OG, Duerden JM, Bartlett SM, Sparks JD, Sparks CE, Gibbons GF. The role of pancreatic hormones in the regulation of lipid storage, oxidation and secretion in primary cultures of rat hepatocytes. Short- and long-term effects. The Biochemical Journal. 381-6. PMID 1310593 DOI: 10.1042/Bj2810381  0.428
1991 Corsetti JP, Sterry JA, Sparks JD, Sparks CE, Weintraub M. Effect of weight loss on serum lipoprotein(a) concentrations in an obese population Clinical Chemistry. 37: 1191-1195. DOI: 10.1093/Clinchem/37.7.1191  0.35
1990 Backus JW, Eagleton MJ, Harris SG, Sparks CE, Sparks JD, Smith HC. Quantitation of endogenous liver apolipoprotein B mRNA editing. Biochemical and Biophysical Research Communications. 170: 513-8. PMID 2383256 DOI: 10.1016/0006-291X(90)92121-F  0.427
1989 Sparks JD, Sparks CE, Miller LL. Insulin effects on apolipoprotein B production by normal, diabetic and treated-diabetic rat liver and cultured rat hepatocytes. The Biochemical Journal. 261: 83-8. PMID 2673217 DOI: 10.1042/Bj2610083  0.512
1989 Kwong TC, Sparks JD, Pryce DJ, Cianci JF, Sparks CE. Inhibition of apolipoprotein B net synthesis and secretion from cultured rat hepatocytes by the calcium-channel blocker diltiazem Biochemical Journal. 263: 411-415. PMID 2597113 DOI: 10.1042/Bj2630411  0.479
1988 Sparks JD, Sparks CE, Bolognino M, Roncone AM, Jackson TK, Amatruda JM. Effects of nonketotic streptozotocin diabetes on apolipoprotein B synthesis and secretion by primary cultures of rat hepatocytes. The Journal of Clinical Investigation. 82: 37-43. PMID 3292589 DOI: 10.1172/Jci113597  0.47
1988 Jackson TK, Salhanick AI, Sparks JD, Sparks CE, Bolognino M, Amatruda JM. Insulin-mimetic effects of vanadate in primary cultures of rat hepatocytes. Diabetes. 37: 1234-40. PMID 3044889 DOI: 10.2337/Diab.37.9.1234  0.456
1987 Sparks CE, Sparks JD, Bolognino M, Salhanick A, Strumph PS, Amatruda JM. Insulin effects on apolipoprotein B lipoprotein synthesis and secretion by primary cultures of rat hepatocytes. Metabolism: Clinical and Experimental. 35: 1128-36. PMID 3537632 DOI: 10.1016/0026-0495(86)90026-0  0.543
1986 Sparks JD, Bolognino M, Trax PA, Sparks CE. The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins. Atherosclerosis. 61: 205-11. PMID 2429674 DOI: 10.1016/0021-9150(86)90139-5  0.435
1985 Sparks JD, Sparks CE. Apolipoprotein B and lipoprotein metabolism Advances in Lipid Research. 21: 1-46. PMID 3895843 DOI: 10.1016/B978-0-12-024921-3.50007-1  0.385
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