Priscilla A. Furth - Publications

Affiliations: 
University of Maryland School of Medicine, Baltimore, MD, United States 
Area:
Genetics, Molecular Biology, Cell Biology

103 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Furth PA, Wang W, Kang K, Rooney BL, Keegan G, Muralidaran V, Wong J, Shearer C, Zou X, Flaws JA. Overexpression of Estrogen Receptor α in Mammary Glands of Aging Mice Is Associated with a Proliferative Risk Signature and Generation of Estrogen Receptor α-Positive Mammary Adenocarcinomas. The American Journal of Pathology. 193: 103-120. PMID 36464513 DOI: 10.1016/j.ajpath.2022.09.008  0.327
2022 Furth PA, Wang W, Kang K, Rooney BL, Keegan G, Muralidaran V, Zou X, Flaws JA. Esr1 but Not CYP19A1 Overexpression in Mammary Epithelial Cells during Reproductive Senescence Induces Pregnancy-Like Proliferative Mammary Disease Responsive to Anti-Hormonals. The American Journal of Pathology. 193: 84-102. PMID 36464512 DOI: 10.1016/j.ajpath.2022.09.007  0.341
2022 Alothman SJ, Kang K, Liu X, Krawczyk E, Azhar RI, Hu R, Goerlitz D, Kallakury BV, Furth PA. Characterization of transcriptome diversity and in vitro behavior of primary human high-risk breast cells. Scientific Reports. 12: 6159. PMID 35459280 DOI: 10.1038/s41598-022-10246-4  0.314
2019 Saenz FR, Ory V, Schmidt MO, Kallakury BV, Mueller SC, Furth PA, Wellstein A, Riegel AT. Depletion of the Transcriptional Coactivator Amplified in Breast Cancer 1 (AIB1) Uncovers Functionally Distinct Subpopulations in Triple-Negative Breast Cancer. Neoplasia (New York, N.Y.). 21: 963-973. PMID 31437536 DOI: 10.1016/J.Neo.2019.07.001  0.445
2018 Furth PA. Peroxisome proliferator-activated receptor gamma and BRCA1. Endocrine-Related Cancer. PMID 30444720 DOI: 10.1530/Erc-18-0449  0.34
2018 Alamri AM, Liu X, Blancato JK, Haddad BR, Wang W, Zhong X, Choudhary S, Krawczyk E, Kallakury BV, Davidson BJ, Furth PA. Expanding primary cells from mucoepidermoid and other salivary gland neoplasms for genetic and chemosensitivity testing. Disease Models & Mechanisms. 11. PMID 29419396 DOI: 10.1242/Dmm.031716  0.347
2018 Ory V, Kietzman WB, Boeckelman J, Kallakury BV, Wellstein A, Furth PA, Riegel AT. The PPARγ agonist efatutazone delays invasive progression and induces differentiation of ductal carcinoma in situ. Breast Cancer Research and Treatment. PMID 29350308 DOI: 10.1007/S10549-017-4649-Y  0.315
2017 Alothman SJ, Wang W, Goerlitz DS, Islam M, Zhong X, Kishore A, Azhar RI, Kallakury BV, Furth PA. Responsiveness of Brca1 and Trp53 Deficiency-Induced Mammary Preneoplasia to Selective Estrogen Modulators versus an Aromatase Inhibitor in Mus musculus. Cancer Prevention Research (Philadelphia, Pa.). PMID 28283467 DOI: 10.1158/1940-6207.Capr-16-0268  0.455
2017 Alothman SJ, Chao S, Wang W, Furth PA. Abstract 2234: Efatutazone reduces mammosphere formation inBrca1WT/fl11/Cre/p53+/-andBrca1fl11/fl11/Cre/p53+/-mice Cancer Research. 77: 2234-2234. DOI: 10.1158/1538-7445.Am2017-2234  0.304
2016 Alamri AM, Kang K, Groeneveld S, Wang W, Zhong X, Kallakury BV, Hennighausen L, Liu X, Furth PA. Primary cancer cell culture: mammary-optimized versus conditional-reprogramming. Endocrine-Related Cancer. PMID 27267121 DOI: 10.1530/Erc-16-0071  0.373
2016 Alothman SJ, Wang W, Kallakury BV, Furth P. Abstract 656: Histological and 3D morphological evaluation of mammary cancers and primary cells from genetically engineered mice with only one copy of Brca1 disrupted in combination with Trp53 haploinsufficiency Cancer Research. 76: 656-656. DOI: 10.1158/1538-7445.Am2016-656  0.4
2016 Alamri AM, Liu X, Wang W, Zhong X, Kallakury B, Davidson B, Furth PA. Abstract 4280: Paralleled workflow for expansion of limited patient material using CRC forin vitro/PDX/biological/genetic studies of a low-grade mucoepidermoid carcinoma Cancer Research. 76: 4280-4280. DOI: 10.1158/1538-7445.Am2016-4280  0.375
2015 Dabydeen SA, Kang K, Díaz-Cruz ES, Alamri A, Axelrod ML, Bouker KB, Al-Kharboosh R, Clarke R, Hennighausen L, Furth PA. Comparison of tamoxifen and letrozole response in mammary preneoplasia of ER and aromatase overexpressing mice defines an immune-associated gene signature linked to tamoxifen resistance. Carcinogenesis. 36: 122-32. PMID 25421723 DOI: 10.1093/Carcin/Bgu237  0.411
2015 Alothman S, Groeneveld S, Alamri A, Kallakury B, Furth PA. Abstract 2286: Spontaneous mammary cancer development in genetically engineered mice with only one copy of Brca1 disrupted in combination with Trp53 haploinsufficiency Cancer Research. 75: 2286-2286. DOI: 10.1158/1538-7445.Am2015-2286  0.447
2014 Bae WK, Yoo KH, Lee JS, Kim Y, Chung IJ, Park MH, Yoon JH, Furth PA, Hennighausen L. The methyltransferase EZH2 is not required for mammary cancer development, although high EZH2 and low H3K27me3 correlate with poor prognosis of ER-positive breast cancers. Molecular Carcinogenesis. PMID 25043748 DOI: 10.1002/Mc.22188  0.435
2014 Mahmoodzadeh S, Leber J, Zhang X, Jaisser F, Messaoudi S, Morano I, Furth PA, Dworatzek E, Regitz-Zagrosek V. Cardiomyocyte-specific Estrogen Receptor Alpha Increases Angiogenesis, Lymphangiogenesis and Reduces Fibrosis in the Female Mouse Heart Post-Myocardial Infarction. Journal of Cell Science & Therapy. 5: 153. PMID 24977106 DOI: 10.4172/2157-7013.1000153  0.303
2014 Cabrera MC, Tilahun E, Nakles R, Diaz-Cruz ES, Charabaty A, Suy S, Jackson P, Ley L, Slack R, Jha R, Collins SP, Haddad N, Kallakury BV, Schroeder T, Pishvaian MJ, ... Furth PA, et al. Human Pancreatic Cancer-Associated Stellate Cells Remain Activated after in vivo Chemoradiation. Frontiers in Oncology. 4: 102. PMID 24847445 DOI: 10.3389/Fonc.2014.00102  0.337
2014 Okolowsky N, Furth PA, Hamel PA. Oestrogen receptor-alpha regulates non-canonical Hedgehog-signalling in the mammary gland Developmental Biology. 391: 219-229. PMID 24769368 DOI: 10.1016/J.Ydbio.2014.04.007  0.377
2014 Assefnia S, Kang K, Groeneveld S, Yamaji D, Dabydeen S, Alamri A, Liu X, Hennighausen L, Furth PA. Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer. Endocrine-Related Cancer. 21: 443-57. PMID 24692510 DOI: 10.1530/ERC-14-0032  0.313
2014 Dabydeen SA, Furth PA. Genetically engineered ERα-positive breast cancer mouse models. Endocrine-Related Cancer. 21: R195-208. PMID 24481326 DOI: 10.1530/Erc-13-0512  0.446
2014 Ory V, Tassi E, Cavalli LR, Sharif GM, Saenz F, Baker T, Schmidt MO, Mueller SC, Furth PA, Wellstein A, Riegel AT. The nuclear coactivator amplified in breast cancer 1 maintains tumor-initiating cells during development of ductal carcinoma in situ. Oncogene. 33: 3033-42. PMID 23851504 DOI: 10.1038/Onc.2013.263  0.434
2014 Furth PA. STAT signaling in different breast cancer sub-types. Molecular and Cellular Endocrinology. 382: 612-5. PMID 23562422 DOI: 10.1016/J.Mce.2013.03.023  0.379
2014 Bae WK, Cho S, Chung I, Furth PA, Hennighausen L. The histone methyltransferase EZH2 and breast cancer development: EZH2 and H3K27me3 correlation with prognosis of ER-positive cancers. Journal of Clinical Oncology. 32: e11537-e11537. DOI: 10.1200/Jco.2014.32.15_Suppl.E11537  0.424
2014 Alothman SJ, Wang W, Furth PA. Abstract 5576: Tamoxifen fails to induce regression of mammary preneoplasia in mice lacking either one or two intact BRCA1 genes in combination with p53 haploinsufficiency but without evidence of in vivo agonist activity Cancer Research. 74: 5576-5576. DOI: 10.1158/1538-7445.Am2014-5576  0.399
2014 Alamri AM, Groeneveld S, Kang K, Dabydeen S, Wang W, Hennighausen L, Kallakury B, Liu X, Furth PA. Abstract 3918: Characterizing growth features, allograft generation and transcriptomes of cultured conditionally reprogrammed cells (CRC) prepared from primary triple negative cancer from Brca1-mutant mice Cancer Research. 74: 3918-3918. DOI: 10.1158/1538-7445.Am2014-3918  0.413
2014 Liu X, Krawczyk E, Palechor-Ceron N, Wang W, Yuan H, Dakic A, Simic V, Kullakury B, Furth P, Schlegel R. Abstract 2972: Conditionally reprogrammed cells (CRCs): A new model for cancer research and personalized medicine Cancer Research. 74: 2972-2972. DOI: 10.1158/1538-7445.Am2014-2972  0.387
2013 Nakles RE, Kallakury BV, Furth PA. The PPARγ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency. The American Journal of Pathology. 182: 1976-85. PMID 23664366 DOI: 10.1016/J.Ajpath.2013.02.006  0.464
2013 Nakles RE, Millman SL, Cabrera MC, Johnson P, Mueller S, Hoppe PS, Schroeder T, Furth PA. Time-lapse imaging of primary preneoplastic mammary epithelial cells derived from genetically engineered mouse models of breast cancer. Journal of Visualized Experiments : Jove. PMID 23425702 DOI: 10.3791/50198  0.359
2013 Nakles RE, Millman S, Cabrera MC, Johnson P, Mueller SC, Hoppe PS, Schroeder T, Furth PA. Characterization of primary mammary epithelial cells with loss of BRCA1at a single cell level Bmc Proceedings. 7. DOI: 10.1186/1753-6561-7-S2-P58  0.371
2013 Dabydeen SA, Wang W, Diaz-Cruz ES, Kopelovich L, Glazer RI, Furth PA. Abstract 197: Reduction in lobular but not ductal hyperplasia by the PGR inhibitor ORG33628 in a CYP19A1 overexpressing mouse model of breast cancer risk. Cancer Research. 73: 197-197. DOI: 10.1158/1538-7445.Am2013-197  0.477
2013 Ory V, Tassi E, Cavalli L, Saenz F, Baker T, Mueller S, Furth P, Wellstein A, Riegel A. Abstract 1404: The nuclear coactivator amplified in breast cancer 1 promotes the initiation and the development of ductal carcinomain situ. Cancer Research. 73: 1404-1404. DOI: 10.1158/1538-7445.Am2013-1404  0.47
2013 Ory V, Tassi E, Cavalli L, Sharif G, Saenz F, Baker T, Schmidt M, Mueller S, Furth P, Wellstein A, Riegel A. Abstract P5-07-03: The nuclear coactivator amplified in breast cancer 1 maintains tumor initiating cells during development of ductal carcinoma in situ Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P5-07-03  0.415
2013 Diaz-Cruz E, Dabydeen S, Al-Kharboosh R, Wang W, Furth P. Abstract P4-11-01: Effect of letrozole is superior to tamoxifen in limiting preneoplasia in both ERa and aromatase over-expressing mice Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P4-11-01  0.46
2012 Miermont AM, Cabrera MC, Frech SM, Nakles RE, Diaz-Cruz ES, Shiffert MT, Furth PA. Association of Over-Expressed Estrogen Receptor Alpha with Development of Tamoxifen Resistant Hyperplasia and Adenocarcinomas in Genetically Engineered Mice. Anatomy & Physiology : Current Research. PMID 24575359  0.317
2012 Furth PA. Cancer prevention as biomodulation: targeting the initiating stimulus and secondary adaptations. Annals of the New York Academy of Sciences. 1271: 1-9. PMID 23050958 DOI: 10.1111/J.1749-6632.2012.06736.X  0.353
2012 Cabrera MC, Díaz-Cruz ES, Kallakury BV, Pishvaian MJ, Grubbs CJ, Muccio DD, Furth PA. The CDK4/6 inhibitor PD0332991 reverses epithelial dysplasia associated with abnormal activation of the cyclin-CDK-Rb pathway. Cancer Prevention Research (Philadelphia, Pa.). 5: 810-21. PMID 22508966 DOI: 10.1158/1940-6207.Capr-11-0532-T  0.315
2011 Furth PA, Nakles RE, Millman S, Diaz-Cruz ES, Cabrera MC. Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer. Breast Cancer Research : Bcr. 13: 220. PMID 22018398 DOI: 10.1186/Bcr2921  0.341
2011 Díaz-Cruz ES, Sugimoto Y, Gallicano GI, Brueggemeier RW, Furth PA. Comparison of increased aromatase versus ERα in the generation of mammary hyperplasia and cancer Cancer Research. 71: 5477-5487. PMID 21840986 DOI: 10.1158/0008-5472.CAN-10-4652  0.372
2011 Furth PA, Cabrera MC, Díaz-Cruz ES, Millman S, Nakles RE. Assessing estrogen signaling aberrations in breast cancer risk using genetically engineered mouse models. Annals of the New York Academy of Sciences. 1229: 147-55. PMID 21793850 DOI: 10.1111/J.1749-6632.2011.06086.X  0.432
2011 Nakles RE, Shiffert MT, Díaz-Cruz ES, Cabrera MC, Alotaiby M, Miermont AM, Riegel AT, Furth PA. Altered AIB1 or AIB1Δ3 expression impacts ERα effects on mammary gland stromal and epithelial content. Molecular Endocrinology (Baltimore, Md.). 25: 549-63. PMID 21292825 DOI: 10.1210/me.2010-0114  0.345
2011 Cabrera MC, Diaz-Cruz ES, Pishvaian MJ, Muccio D, Grubbs C, Furth P. Abstract A20: Investigating the role of cell cycle proteins and CDK4/6 inhibitor PD0332991 in the redifferentiation of irreversible dysplasia Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-A20  0.361
2011 Fogarty S, Shiffert M, Berezowski K, Hartmann D, Cabrera M, Sidawy M, Furth P, Liu M. P5-11-03: Real-Time Imaging of Human Breast Tissue with Reflectance Confocal Microscopy: Correlation with Routine Pathology. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P5-11-03  0.354
2010 Diaz-Cruz ES, Cabrera MC, Nakles R, Rutstein BH, Furth PA. BRCA1 deficient mouse models to study pathogenesis and therapy of triple negative breast cancer. Breast Disease. 32: 85-97. PMID 21778574 DOI: 10.3233/Bd-2010-0308  0.389
2010 Díaz-Cruz ES, Furth PA. Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia. Cancer Research. 70: 3965-74. PMID 20466998 DOI: 10.1158/0008-5472.Can-09-3450  0.365
2010 Miermont AM, Parrish AR, Furth PA. Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis. Carcinogenesis. 31: 1124-31. PMID 20181624 DOI: 10.1093/Carcin/Bgq048  0.45
2010 Angel MSJ, Furth PA, Kallakury BVS, Dumitrescu RG, Catalin M, Spear SL, Freudenheim JL, Shields PG. Abstract 4706: Gene and protein expression of TGF-beta signaling pathway molecules in women undergoing reduction mammoplasty Cancer Research. 70: 4706-4706. DOI: 10.1158/1538-7445.Am10-4706  0.305
2009 Kleinberg DL, Wood TL, Furth PA, Lee AV. Growth hormone and insulin-like growth factor-I in the transition from normal mammary development to preneoplastic mammary lesions. Endocrine Reviews. 30: 51-74. PMID 19075184 DOI: 10.1210/Er.2008-0022  0.371
2009 Diaz‐Cruz ES, Nakles RE, Sugimoto Y, Brueggemeier RW, Furth PA. Abstract A26: Aromatase over‐expression results in the development of ductal growth abnormalities in the mammary gland of a conditional transgenic mouse model Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-A26  0.466
2008 Fereshteh MP, Tilli MT, Kim SE, Xu J, O'Malley BW, Wellstein A, Furth PA, Riegel AT. The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Research. 68: 3697-706. PMID 18483252 DOI: 10.1158/0008-5472.Can-07-6702  0.454
2008 Tilli MT, Parrish AR, Cotarla I, Jones LP, Johnson MD, Furth PA. Comparison of mouse mammary gland imaging techniques and applications: reflectance confocal microscopy, GFP imaging, and ultrasound. Bmc Cancer. 8: 21. PMID 18215290 DOI: 10.1186/1471-2407-8-21  0.326
2008 Frech MS, Torre KM, Robinson GW, Furth PA. Loss of cyclin D1 in concert with deregulated estrogen receptor alpha expression induces DNA damage response activation and interrupts mammary gland morphogenesis. Oncogene. 27: 3186-93. PMID 18071314 DOI: 10.1038/Sj.Onc.1210974  0.412
2008 Jones LP, Tilli MT, Assefnia S, Torre K, Halama ED, Parrish A, Rosen EM, Furth PA. Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer. Oncogene. 27: 794-802. PMID 17653086 DOI: 10.1038/Sj.Onc.1210674  0.449
2008 Assefnia S, Mitchell S, Furth P. Abstract B71: Decreased expression of Tgfβ family members appears to be an acquired phenotype of progression to malignancy in the context of loss of Brca1 in mammary epithelial cells. Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-B71  0.416
2008 Miermont A, Furth P. Abstract A6: Stat5a and pregnancy protection in the CERM mouse model Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-A6  0.409
2008 Tilli MT, Fereshteh MP, Torre KM, Riegel AT, Furth PA. The Role of the Estrogen Receptor Coactivator, Amplified in Breast Cancer 1 (AIB1), in Her2/neu-Initiated Mouse Mammary Carcinogenesis and Tamoxifen Resistance. Biology of Reproduction. 78: 103-103. DOI: 10.1093/Biolreprod/78.S1.103D  0.39
2007 Tilli MT, Cabrera MC, Parrish AR, Torre KM, Sidawy MK, Gallagher AL, Makariou E, Polin SA, Liu MC, Furth PA. Real-time imaging and characterization of human breast tissue by reflectance confocal microscopy. Journal of Biomedical Optics. 12: 051901. PMID 17994884 DOI: 10.1117/1.2799187  0.321
2007 Greenfeld CR, Pepling ME, Babus JK, Furth PA, Flaws JA. BAX regulates follicular endowment in mice. Reproduction (Cambridge, England). 133: 865-76. PMID 17616717 DOI: 10.1530/Rep-06-0270  0.382
2007 Herschkowitz JI, Simin K, Weigman VJ, Mikaelian I, Usary J, Hu Z, Rasmussen KE, Jones LP, Assefnia S, Chandrasekharan S, Backlund MG, Yin Y, Khramtsov AI, Bastein R, Quackenbush J, ... ... Furth PA, et al. Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors. Genome Biology. 8: R76. PMID 17493263 DOI: 10.1186/Gb-2007-8-5-R76  0.389
2007 Greenfeld CR, Babus JK, Furth PA, Marion S, Hoyer PB, Flaws JA. BAX is involved in regulating follicular growth, but is dispensable for follicle atresia in adult mouse ovaries. Reproduction (Cambridge, England). 133: 107-16. PMID 17244737 DOI: 10.1530/Rep-06-0144  0.328
2007 Tomic D, Frech MS, Babus JK, Symonds D, Furth PA, Koos RD, Flaws JA. Effects of ERalpha overexpression on female reproduction in mice. Reproductive Toxicology (Elmsford, N.Y.). 23: 317-25. PMID 17011746 DOI: 10.1016/J.Reprotox.2006.08.004  0.337
2007 Assefnia S, Jones LP, Torre KM, Furth PA. Decreased expression of Tgf‐beta ligands and receptors correlates with an aberrant proliferative response to estrogen in a mouse model of Brca1‐mutation‐related breast cancer. The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A78-C  0.396
2006 Furth PA, Halama ED. What do shifts in indicators of apoptosis indicate about the cancer process? The Journal of Nutrition. 136: 2700S-3S. PMID 16988156 DOI: 10.1093/Jn/136.10.2700S  0.33
2006 Tomic D, Frech MS, Babus JK, Gupta RK, Furth PA, Koos RD, Flaws JA. Methoxychlor induces atresia of antral follicles in ERalpha-overexpressing mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. 93: 196-204. PMID 16787999 DOI: 10.1093/Toxsci/Kfl040  0.34
2006 Katiyar P, Ma Y, Fan S, Pestell RG, Furth PA, Rosen EM. Regulation of progesterone receptor signaling by BRCA1 in mammary cancer. Nuclear Receptor Signaling. 4: e006. PMID 16741564 DOI: 10.1621/Nrs.04006  0.412
2006 Ma Y, Katiyar P, Jones LP, Fan S, Zhang Y, Furth PA, Rosen EM. The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells. Molecular Endocrinology (Baltimore, Md.). 20: 14-34. PMID 16109739 DOI: 10.1210/Me.2004-0488  0.448
2005 Frech MS, Jones LP, Furth PA. Validation of transgenic models of breast cancer: ductal carcinoma in situ (DCIS) and Brca1-mutation-related breast cancer. Breast Cancer Online : Bco. 8. PMID 24371431 DOI: 10.1017/S1470903105003135  0.433
2005 Parrish A, Halama E, Tilli MT, Freedman M, Furth PA. Reflectance confocal microscopy for characterization of mammary ductal structures and development of neoplasia in genetically engineered mouse models of breast cancer. Journal of Biomedical Optics. 10: 051602. PMID 16292950 DOI: 10.1117/1.2065827  0.384
2005 Bachelier R, Xu X, Li C, Qiao W, Furth PA, Lubet RA, Deng CX. Effect of bilateral oophorectomy on mammary tumor formation in BRCA1 mutant mice. Oncology Reports. 14: 1117-20. PMID 16211273 DOI: 10.3892/Or.14.5.1117  0.597
2005 Jones LP, Li M, Halama ED, Ma Y, Lubet R, Grubbs CJ, Deng CX, Rosen EM, Furth PA. Promotion of mammary cancer development by tamoxifen in a mouse model of Brca1-mutation-related breast cancer. Oncogene. 24: 3554-62. PMID 15750629 DOI: 10.1038/Sj.Onc.1208426  0.499
2005 Tilli MT, Reiter R, Oh AS, Henke RT, McDonnell K, Gallicano GI, Furth PA, Riegel AT. Overexpression of an N-terminally truncated isoform of the nuclear receptor coactivator amplified in breast cancer 1 leads to altered proliferation of mammary epithelial cells in transgenic mice Molecular Endocrinology. 19: 644-656. PMID 15550471 DOI: 10.1210/Me.2004-0106  0.401
2004 Cotarla I, Ren S, Zhang Y, Gehan E, Singh B, Furth PA. Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers. International Journal of Cancer. 108: 665-71. PMID 14696092 DOI: 10.1002/Ijc.11619  0.406
2003 Tilli MT, Frech MS, Steed ME, Hruska KS, Johnson MD, Flaws JA, Furth PA. Introduction of estrogen receptor-alpha into the tTA/TAg conditional mouse model precipitates the development of estrogen-responsive mammary adenocarcinoma. The American Journal of Pathology. 163: 1713-9. PMID 14578170 DOI: 10.1016/S0002-9440(10)63529-8  0.402
2003 Tilli MT, Furth PA. Conditional mouse models demonstrate oncogene-dependent differences in tumor maintenance and recurrence. Breast Cancer Research : Bcr. 5: 202-5. PMID 12817992 DOI: 10.1186/Bcr614  0.42
2003 Li M, Ren S, Tilli MT, Flaws JA, Lubet R, Grubbs CJ, Furth PA. Chemoprevention of mammary carcinogenesis in a transgenic mouse model by alpha-difluoromethylornithine (DFMO) in the diet is associated with decreased cyclin D1 activity. Oncogene. 22: 2568-72. PMID 12730671 DOI: 10.1038/Sj.Onc.1206314  0.44
2003 Xu X, Aprelikova O, Moens P, Deng CX, Furth PA. Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice Development. 130: 2001-2012. PMID 12642502 DOI: 10.1242/Dev.00410  0.511
2003 Clevenger CV, Furth PA, Hankinson SE, Schuler LA. The role of prolactin in mammary carcinoma. Endocrine Reviews. 24: 1-27. PMID 12588805 DOI: 10.1210/Er.2001-0036  0.383
2002 Hruska KS, Tilli MT, Ren S, Cotarla I, Kwong T, Li M, Fondell JD, Hewitt JA, Koos RD, Furth PA, Flaws JA. Conditional over-expression of estrogen receptor alpha in a transgenic mouse model. Transgenic Research. 11: 361-72. PMID 12212839 DOI: 10.1023/A:1016376100186  0.413
2002 Ren S, Hong RC, Li M, Furth PA. Loss of Stat5a delays mammary cancer progression in a mouse model Oncogene. 21: 4335-4339. PMID 12082622 DOI: 10.1038/Sj.Onc.1205484  0.485
2002 Desai KV, Xiao N, Wang W, Gangi L, Greene J, Powell JI, Dickson R, Furth P, Hunter K, Kucherlapati R, Simon R, Liu ET, Green JE. Initiating oncogenic event determines gene-expression patterns of human breast cancer models. Proceedings of the National Academy of Sciences of the United States of America. 99: 6967-72. PMID 12011455 DOI: 10.1073/Pnas.102172399  0.426
2002 Capuco AV, Li M, Long E, Ren S, Hruska KS, Schorr K, Furth PA. Concurrent pregnancy retards mammary involution: effects on apoptosis and proliferation of the mammary epithelium after forced weaning of mice. Biology of Reproduction. 66: 1471-6. PMID 11967212 DOI: 10.1095/Biolreprod66.5.1471  0.361
2001 Cui Y, Li M, Walton KD, Sun K, Hanover JA, Furth PA, Hennighausen L. The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue. Genomics. 78: 129-34. PMID 11735219 DOI: 10.1006/Geno.2001.6661  0.369
2001 Xu X, Qiao W, Linke SP, Cao L, Li WM, Furth PA, Harris CC, Deng CX. Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nature Genetics. 28: 266-71. PMID 11431698 DOI: 10.1038/90108  0.599
2001 Lewis BC, Hudgins S, Lewis A, Schorr K, Sommer R, Peterson RE, Flaws JA, Furth PA. In utero and lactational treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs mammary gland differentiation but does not block the response to exogenous estrogen in the postpubertal female rat. Toxicological Sciences : An Official Journal of the Society of Toxicology. 62: 46-53. PMID 11399792 DOI: 10.1093/Toxsci/62.1.46  0.328
2001 Flaws JA, Hirshfield AN, Hewitt JA, Babus JK, Furth PA. Effect of bcl-2 on the primordial follicle endowment in the mouse ovary. Biology of Reproduction. 64: 1153-9. PMID 11259262 DOI: 10.1095/Biolreprod64.4.1153  0.373
2000 Zhang M, Shi Y, Magit D, Furth PA, Sager R. Reduced mammary tumor progression in WAP-TAg/WAP-maspin bitransgenic mice. Oncogene. 19: 6053-8. PMID 11146557 DOI: 10.1038/Sj.Onc.1204006  0.376
2000 Furth PA. Conditional control of gene expression in the mammary gland. Journal of Mammary Gland Biology and Neoplasia. 2: 373-83. PMID 10935025 DOI: 10.1023/A:1026399329934  0.336
2000 Li M, Lewis B, Capuco AV, Laucirica R, Furth PA. WAP-TAg transgenic mice and the study of dysregulated cell survival, proliferation, and mutation during breast carcinogenesis. Oncogene. 19: 1010-9. PMID 10713684 DOI: 10.1038/Sj.Onc.1203271  0.458
2000 Furth PA, Bar-Peled U, Li M, Lewis A, Laucirica R, Jäger R, Weiher H, Russell RG. Loss of anti-mitotic effects of Bcl-2 with retention of anti-apoptotic activity during tumor progression in a mouse model. Oncogene. 18: 6589-96. PMID 10597263 DOI: 10.1038/Sj.Onc.1203073  0.41
1999 Zhang M, Magit D, Botteri F, Shi HY, He K, Li M, Furth P, Sager R. Maspin plays an important role in mammary gland development. Developmental Biology. 215: 278-87. PMID 10545237 DOI: 10.1006/Dbio.1999.9442  0.382
1999 Schorr K, Li M, Krajewski S, Reed JC, Furth PA. Bcl-2 gene family and related proteins in mammary gland involution and breast cancer. Journal of Mammary Gland Biology and Neoplasia. 4: 153-64. PMID 10426394 DOI: 10.1023/A:1018773123899  0.42
1999 Furth PA. Introduction: mammary gland involution and apoptosis of mammary epithelial cells. Journal of Mammary Gland Biology and Neoplasia. 4: 123-7. PMID 10426390 DOI: 10.1023/A:1018764922082  0.339
1998 Furth PA, Li M, Hennighausen L. Studying development of disease through temporally controlled gene expression in the salivary gland. Annals of the New York Academy of Sciences. 842: 181-7. PMID 9599308 DOI: 10.1111/J.1749-6632.1998.Tb09646.X  0.38
1997 Wagner KU, Wall RJ, St-Onge L, Gruss P, Wynshaw-Boris A, Garrett L, Li M, Furth PA, Hennighausen L. Cre-mediated gene deletion in the mammary gland. Nucleic Acids Research. 25: 4323-30. PMID 9336464 DOI: 10.1093/Nar/25.21.4323  0.416
1997 Li M, Liu X, Robinson G, Bar-Peled U, Wagner KU, Young WS, Hennighausen L, Furth PA. Mammary-derived signals activate programmed cell death during the first stage of mammary gland involution. Proceedings of the National Academy of Sciences of the United States of America. 94: 3425-30. PMID 9096410 DOI: 10.1073/Pnas.94.7.3425  0.316
1996 St-Onge L, Furth PA, Gruss P. Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter. Nucleic Acids Research. 24: 3875-7. PMID 8871571 DOI: 10.1093/Nar/24.19.3875  0.361
1996 Nass SJ, Li M, Amundadottir LT, Furth PA, Dickson RB. Role for Bcl-xL in the regulation of apoptosis by EGF and TGF beta 1 in c-myc overexpressing mammary epithelial cells. Biochemical and Biophysical Research Communications. 227: 248-56. PMID 8858133 DOI: 10.1006/Bbrc.1996.1497  0.317
1996 Hennighausen L, Wall RJ, Tillmann U, Li M, Furth PA. Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system. Journal of Cellular Biochemistry. 59: 463-72. PMID 8749716 DOI: 10.1002/Jcb.240590407  0.415
1996 Robinson GW, Smith GH, Gallahan D, Zimmer A, Furth PA, Hennighausen L. Understanding mammary gland development through the imbalanced expression of growth regulators. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 206: 159-68. PMID 8725283 DOI: 10.1002/(Sici)1097-0177(199606)206:2<159::Aid-Aja5>3.0.Co;2-H  0.359
1996 Ewald D, Li M, Efrat S, Auer G, Wall RJ, Furth PA, Hennighausen L. Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen. Science (New York, N.Y.). 273: 1384-6. PMID 8703072 DOI: 10.1126/Science.273.5280.1384  0.339
1996 Furth PA, Kerr D, Wall R. Gene transfer by jet injection into differentiated tissues of living animals and in organ culture. Molecular Biotechnology. 4: 121-7. PMID 8556427 DOI: 10.1007/Bf02921606  0.307
1996 Kerr D, Furth P, Powell A, Wall R. Expression of gene‐gun injected plasmid DNA in the ovine mammary gland and in lymph nodes draining the injection site Animal Biotechnology. 7: 33-45. DOI: 10.1080/10495399609525846  0.334
1994 Furth PA, St Onge L, Böger H, Gruss P, Gossen M, Kistner A, Bujard H, Hennighausen L. Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter. Proceedings of the National Academy of Sciences of the United States of America. 91: 9302-6. PMID 7937760 DOI: 10.1073/Pnas.91.20.9302  0.377
1991 Furth PA, Hennighausen L, Baker C, Beatty B, Woychick R. The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice. Nucleic Acids Research. 19: 6205-8. PMID 1956779 DOI: 10.1093/Nar/19.22.6205  0.348
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