Markus H. Kuehn, Ph.D. - Publications

Affiliations: 
2000 Saint Louis University, St. Louis, MO, United States 
Area:
Cell Biology, Ophthalmology, Genetics

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Cheng L, Cring MR, Wadkins DA, Kuehn MH. Absence of Connexin 43 results in smaller retinas and arrested, depolarized retinal progenitor cells in human retinal organoids. Stem Cells (Dayton, Ohio). PMID 35263762 DOI: 10.1093/stmcls/sxac017  0.345
2021 Gramlich OW, Godwin CR, Wadkins D, Elwood BW, Kuehn MH. Early Functional Impairment in Experimental Glaucoma Is Accompanied by Disruption of the GABAergic System and Inceptive Neuroinflammation. International Journal of Molecular Sciences. 22. PMID 34299211 DOI: 10.3390/ijms22147581  0.312
2020 Zhu W, Godwin CR, Cheng L, Scheetz TE, Kuehn MH. Transplantation of iPSC-TM stimulates division of trabecular meshwork cells in human eyes. Scientific Reports. 10: 2905. PMID 32076077 DOI: 10.1038/S41598-020-59941-0  0.375
2018 van der Heide CJ, Alward WLM, Flamme-Wiese M, Riker M, Syed NA, Anderson MG, Carter K, Kuehn MH, Stone EM, Mullins RF, Fingert JH. Histochemical Analysis of Glaucoma Caused by a Myocilin Mutation in a Human Donor Eye. Ophthalmology. Glaucoma. 1: 132-138. PMID 30906929 DOI: 10.1016/J.Ogla.2018.08.004  0.377
2018 Grozdanic SD, Lazic T, Kecova H, Mohan K, Kuehn MH. Optical coherence tomography and molecular analysis of sudden acquired retinal degeneration syndrome (SARDS) eyes suggests the immune-mediated nature of retinal damage. Veterinary Ophthalmology. PMID 30109754 DOI: 10.1111/Vop.12597  0.416
2017 Zhu W, Jain A, Gramlich OW, Tucker BA, Sheffield VC, Kuehn MH. Restoration of Aqueous Humor Outflow Following Transplantation of iPSC-Derived Trabecular Meshwork Cells in a Transgenic Mouse Model of Glaucoma. Investigative Ophthalmology & Visual Science. 58: 2054-2062. PMID 28384726 DOI: 10.1167/Iovs.16-20672  0.326
2016 Zhu W, Gramlich OW, Laboissonniere L, Jain A, Sheffield VC, Trimarchi JM, Tucker BA, Kuehn MH. Transplantation of iPSC-derived TM cells rescues glaucoma phenotypes in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 27274060 DOI: 10.1073/Pnas.1604153113  0.391
2016 Gramlich OW, Burand AJ, Brown AJ, Deutsch RJ, Kuehn MH, Ankrum JA. Cryopreserved Mesenchymal Stromal Cells Maintain Potency in a Retinal Ischemia/Reperfusion Injury Model: Toward an off-the-shelf Therapy. Scientific Reports. 6: 26463. PMID 27212469 DOI: 10.1038/Srep26463  0.332
2016 Kuehn MH, Lipsett KA, Menotti-Raymond M, Whitmore SS, Scheetz TE, David VA, O'Brien SJ, Zhao Z, Jens JK, Snella EM, Ellinwood NM, McLellan GJ. A Mutation in LTBP2 Causes Congenital Glaucoma in Domestic Cats (Felis catus). Plos One. 11: e0154412. PMID 27149523 DOI: 10.1371/Journal.Pone.0154412  0.412
2016 Sohn EH, van Dijk HW, Jiao C, Kok PH, Jeong W, Demirkaya N, Garmager A, Wit F, Kucukevcilioglu M, van Velthoven ME, DeVries JH, Mullins RF, Kuehn MH, Schlingemann RO, Sonka M, et al. Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114552 DOI: 10.1073/Pnas.1522014113  0.346
2015 Gramlich OW, Ding QJ, Zhu W, Cook A, Anderson MG, Kuehn MH. Adoptive transfer of immune cells from glaucomatous mice provokes retinal ganglion cell loss in recipients. Acta Neuropathologica Communications. 3: 56. PMID 26374513 DOI: 10.1186/S40478-015-0234-Y  0.426
2015 Yang X, Hondur G, Li M, Cai J, Klein JB, Kuehn MH, Tezel G. Proteomics Analysis of Molecular Risk Factors in the Ocular Hypertensive Human Retina. Investigative Ophthalmology & Visual Science. 56: 5816-30. PMID 26348630 DOI: 10.1167/Iovs.15-17294  0.417
2015 Ahram DF, Alward WL, Kuehn MH. The genetic mechanisms of primary angle closure glaucoma. Eye (London, England). 29: 1251-9. PMID 26206529 DOI: 10.1038/Eye.2015.124  0.305
2015 Ahram DF, Grozdanic SD, Kecova H, Henkes A, Collin RW, Kuehn MH. Variants in Nebulin (NEB) Are Linked to the Development of Familial Primary Angle Closure Glaucoma in Basset Hounds. Plos One. 10: e0126660. PMID 25938837 DOI: 10.1371/Journal.Pone.0126660  0.366
2015 Hazlewood RJ, Roos BR, Solivan-Timpe F, Honkanen RA, Jampol LM, Gieser SC, Meyer KJ, Mullins RF, Kuehn MH, Scheetz TE, Kwon YH, Alward WL, Stone EM, Fingert JH. Heterozygous triplication of upstream regulatory sequences leads to dysregulation of matrix metalloproteinase 19 in patients with cavitary optic disc anomaly. Human Mutation. 36: 369-78. PMID 25581579 DOI: 10.1002/Humu.22754  0.352
2014 Kuehn MH. Immune phenomena in glaucoma and conformational disorders: why is the second eye not involved? Journal of Glaucoma. 23: S59-61. PMID 25275909 DOI: 10.1097/Ijg.0000000000000115  0.365
2013 Scheetz TE, Fingert JH, Wang K, Kuehn MH, Knudtson KL, Alward WL, Boldt HC, Russell SR, Folk JC, Casavant TL, Braun TA, Clark AF, Stone EM, Sheffield VC. A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci. Plos One. 8: e58657. PMID 23536807 DOI: 10.1371/Journal.Pone.0058657  0.344
2012 Ding QJ, Cook AC, Dumitrescu AV, Kuehn MH. Lack of immunoglobulins does not prevent C1q binding to RGC and does not alter the progression of experimental glaucoma. Investigative Ophthalmology & Visual Science. 53: 6370-7. PMID 22918632 DOI: 10.1167/Iovs.12-10442  0.39
2012 Mullins RF, Kuehn MH, Radu RA, Enriquez GS, East JS, Schindler EI, Travis GH, Stone EM. Autosomal recessive retinitis pigmentosa due to ABCA4 mutations: clinical, pathologic, and molecular characterization. Investigative Ophthalmology & Visual Science. 53: 1883-94. PMID 22395892 DOI: 10.1167/Iovs.12-9477  0.483
2011 Yang X, Luo C, Cai J, Powell DW, Yu D, Kuehn MH, Tezel G. Neurodegenerative and inflammatory pathway components linked to TNF-α/TNFR1 signaling in the glaucomatous human retina. Investigative Ophthalmology & Visual Science. 52: 8442-54. PMID 21917936 DOI: 10.1167/Iovs.11-8152  0.353
2011 Zode GS, Kuehn MH, Nishimura DY, Searby CC, Mohan K, Grozdanic SD, Bugge K, Anderson MG, Clark AF, Stone EM, Sheffield VC. Reduction of ER stress via a chemical chaperone prevents disease phenotypes in a mouse model of primary open angle glaucoma. The Journal of Clinical Investigation. 121: 3542-53. PMID 21821918 DOI: 10.1172/Jci58183  0.357
2011 Mullins RF, Dewald AD, Streb LM, Wang K, Kuehn MH, Stone EM. Elevated membrane attack complex in human choroid with high risk complement factor H genotypes. Experimental Eye Research. 93: 565-7. PMID 21729696 DOI: 10.1016/J.Exer.2011.06.015  0.322
2011 Harper MM, Grozdanic SD, Blits B, Kuehn MH, Zamzow D, Buss JE, Kardon RH, Sakaguchi DS. Transplantation of BDNF-secreting mesenchymal stem cells provides neuroprotection in chronically hypertensive rat eyes. Investigative Ophthalmology & Visual Science. 52: 4506-15. PMID 21498611 DOI: 10.1167/Iovs.11-7346  0.364
2011 Trantow CM, Cuffy TL, Fingert JH, Kuehn MH, Anderson MG. Microarray analysis of iris gene expression in mice with mutations influencing pigmentation. Investigative Ophthalmology & Visual Science. 52: 237-48. PMID 20739468 DOI: 10.1167/Iovs.10-5479  0.326
2010 Jiang B, Harper MM, Kecova H, Adamus G, Kardon RH, Grozdanic SD, Kuehn MH. Neuroinflammation in advanced canine glaucoma. Molecular Vision. 16: 2092-108. PMID 21042562  0.319
2010 Grozdanic SD, Lazic T, Kuehn MH, Harper MM, Kardon RH, Kwon YH, Lavik EB, Sakaguchi DS. Exogenous modulation of intrinsic optic nerve neuroprotective activity. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv FüR Klinische Und Experimentelle Ophthalmologie. 248: 1105-16. PMID 20229104 DOI: 10.1007/S00417-010-1336-7  0.353
2010 Tezel G, Yang X, Luo C, Cai J, Kain AD, Powell DW, Kuehn MH, Pierce WM. Hemoglobin expression and regulation in glaucoma: insights into retinal ganglion cell oxygenation. Investigative Ophthalmology & Visual Science. 51: 907-19. PMID 19741249 DOI: 10.1167/Iovs.09-4014  0.38
2010 Grozdanic SD, Kecova H, Harper MM, Nilaweera W, Kuehn MH, Kardon RH. Functional and structural changes in a canine model of hereditary primary angle-closure glaucoma. Investigative Ophthalmology & Visual Science. 51: 255-63. PMID 19661222 DOI: 10.1167/Iovs.09-4081  0.38
2009 Kwon YH, Fingert JH, Kuehn MH, Alward WL. Primary open-angle glaucoma. The New England Journal of Medicine. 360: 1113-24. PMID 19279343 DOI: 10.1056/Nejmra0804630  0.34
2008 Ostoji? J, Grozdani? SD, Syed NA, Hargrove MS, Trent JT, Kuehn MH, Kwon YH, Kardon RH, Sakaguchi DS. Patterns of distribution of oxygen-binding globins, neuroglobin and cytoglobin in human retina. Archives of Ophthalmology (Chicago, Ill. : 1960). 126: 1530-6. PMID 19001220 DOI: 10.1001/Archopht.126.11.1530  0.41
2008 Ostojic J, Grozdanic S, Syed NA, Hargrove MS, Trent JT, Kuehn MH, Kardon RH, Kwon YH, Sakaguchi DS. Neuroglobin and cytoglobin distribution in the anterior eye segment: a comparative immunohistochemical study. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 56: 863-72. PMID 18574250 DOI: 10.1369/Jhc.2008.951392  0.346
2008 Kuehn MH, Kim CY, Jiang B, Dumitrescu AV, Kwon YH. Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion. Experimental Eye Research. 87: 89-95. PMID 18572163 DOI: 10.1016/J.Exer.2008.04.012  0.425
2007 Mullins RF, Kuehn MH, Faidley EA, Syed NA, Stone EM. Differential macular and peripheral expression of bestrophin in human eyes and its implication for best disease. Investigative Ophthalmology & Visual Science. 48: 3372-80. PMID 17591911 DOI: 10.1167/Iovs.06-0868  0.411
2006 Kim CY, Kuehn MH, Clark AF, Kwon YH. Gene expression profile of the adult human retinal ganglion cell layer. Molecular Vision. 12: 1640-8. PMID 17200664  0.332
2006 Kuehn MH, Kim CY, Ostojic J, Bellin M, Alward WL, Stone EM, Sakaguchi DS, Grozdanic SD, Kwon YH. Retinal synthesis and deposition of complement components induced by ocular hypertension. Experimental Eye Research. 83: 620-8. PMID 16677633 DOI: 10.1016/J.Exer.2006.03.002  0.445
2006 Mullins RF, Skeie JM, Malone EA, Kuehn MH. Macular and peripheral distribution of ICAM-1 in the human choriocapillaris and retina. Molecular Vision. 12: 224-35. PMID 16604055  0.305
2006 Ostoji? J, Sakaguchi DS, de Lathouder Y, Hargrove MS, Trent JT, Kwon YH, Kardon RH, Kuehn MH, Betts DM, Grozdani? S. Neuroglobin and cytoglobin: oxygen-binding proteins in retinal neurons. Investigative Ophthalmology & Visual Science. 47: 1016-23. PMID 16505036 DOI: 10.1167/Iovs.05-0465  0.379
2005 Kuehn MH, Fingert JH, Kwon YH. Retinal ganglion cell death in glaucoma: mechanisms and neuroprotective strategies. Ophthalmology Clinics of North America. 18: 383-95, vi. PMID 16054996 DOI: 10.1016/J.Ohc.2005.04.002  0.369
2004 Stone EM, Braun TA, Russell SR, Kuehn MH, Lotery AJ, Moore PA, Eastman CG, Casavant TL, Sheffield VC. Missense variations in the fibulin 5 gene and age-related macular degeneration. The New England Journal of Medicine. 351: 346-53. PMID 15269314 DOI: 10.1056/NEJMOA040833  0.349
2001 Kuehn MH, Stone EM, Hageman GS. Organization of the human IMPG2 gene and its evaluation as a candidate gene in age-related macular degeneration and other retinal degenerative disorders. Investigative Ophthalmology & Visual Science. 42: 3123-9. PMID 11726612  0.592
2001 Alagramam KN, Yuan H, Kuehn MH, Murcia CL, Wayne S, Srisailpathy CRS, Lowry RB, Knaus R, Van Laer L, Bernier FP, Schwartz S, Lee C, Morton CC, Mullins RF, Ramesh A, et al. Mutations in the novel protocadherin PCDH15 cause Usher syndrome type 1F Human Molecular Genetics. 10: 1709-1718. PMID 11487575 DOI: 10.1093/Hmg/10.16.1709  0.34
2001 Ruiz A, Kuehn MH, Andorf JL, Stone E, Hageman GS, Bok D. Genomic organization and mutation analysis of the gene encoding lecithin retinol acyltransferase in human retinal pigment epithelium. Investigative Ophthalmology & Visual Science. 42: 31-7. PMID 11133845  0.581
2000 Kuehn MH, Wietecki DT, Hageman GS. Molecular characterization of the murine orthologue of the human retinal proteoglycan IPM 150. Molecular Vision. 6: 148-56. PMID 10958699  0.61
1999 Kuehn MH, Hageman GS. Expression and characterization of the IPM 150 gene (IMPG1) product, a novel human photoreceptor cell-associated chondroitin-sulfate proteoglycan. Matrix Biology : Journal of the International Society For Matrix Biology. 18: 509-18. PMID 10601738 DOI: 10.1016/S0945-053X(99)00043-8  0.616
1999 Gorin MB, Breitner JC, De Jong PT, Hageman GS, Klaver CC, Kuehn MH, Seddon JM. The genetics of age-related macular degeneration. Molecular Vision. 5: 29. PMID 10562653  0.522
1999 Kuehn MH, Hageman GS. Molecular characterization and genomic mapping of human IPM 200, a second member of a novel family of proteoglycans. Molecular Cell Biology Research Communications : McBrc. 2: 103-10. PMID 10542133 DOI: 10.1006/Mcbr.1999.0161  0.601
1992 Hageman G, Kirchoff-Rempe M, Rotramel J, Kuehn M. Molecular and compositional characterization of interphotoreceptor matrix proteoglycans Experimental Eye Research. 55: 33. DOI: 10.1016/0014-4835(92)90324-L  0.51
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