Year |
Citation |
Score |
2023 |
Toh Y, Wu L, Park S, Wang A, Tu J, Yu W, Zuo M, Carmon KS, Liu QJ. LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands. Scientific Reports. 13: 10796. PMID 37402772 DOI: 10.1038/s41598-023-37856-w |
0.336 |
|
2021 |
Cui J, Toh Y, Park S, Yu W, Tu J, Wu L, Li L, Jacob J, Pan S, Carmon KS, Liu QJ. Drug Conjugates of Antagonistic R-Spondin 4 Mutant for Simultaneous Targeting of Leucine-Rich Repeat-Containing G Protein-Coupled Receptors 4/5/6 for Cancer Treatment. Journal of Medicinal Chemistry. PMID 34406767 DOI: 10.1021/acs.jmedchem.1c00395 |
0.409 |
|
2021 |
Chatterjee T, Zhang S, Posey TA, Jacob J, Wu L, Yu W, Francisco LE, Liu QJ, Carmon KS. Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion. The Journal of Biological Chemistry. 296: 100261. PMID 33837725 DOI: 10.1016/j.jbc.2021.100261 |
0.431 |
|
2020 |
Park S, Wu L, Tu J, Yu W, Toh Y, Carmon KS, Liu QJ. Unlike LGR4, LGR5 potentiates Wnt-β-catenin signaling without sequestering E3 ligases. Science Signaling. 13. PMID 33262293 DOI: 10.1126/scisignal.aaz4051 |
0.413 |
|
2019 |
Tu J, Park S, Yu W, Zhang S, Wu L, Carmon K, Liu QJ. The most common RNF43 mutant G659Vfs*41 is fully functional in inhibiting Wnt signaling and unlikely to play a role in tumorigenesis. Scientific Reports. 9: 18557. PMID 31811196 DOI: 10.1038/S41598-019-54931-3 |
0.412 |
|
2019 |
Zhang S, Chatterjee T, Godoy C, Wu L, Liu QJ, Carmon KS. GPR56 drives colorectal tumor growth and promotes drug resistance through upregulation of MDR1 expression via a RhoA-mediated mechanism. Molecular Cancer Research : McR. PMID 31444231 DOI: 10.1158/1541-7786.Mcr-19-0436 |
0.335 |
|
2018 |
Tan B, Shi X, Zhang J, Qin J, Zhang N, Ren H, Qian M, Siwko S, Carmon K, Liu Q, Han H, Du B, Liu M. Inhibition of Rspo-Lgr4 facilitates checkpoint blockade therapy by switching macrophage polarization. Cancer Research. PMID 29967265 DOI: 10.1158/0008-5472.Can-18-0152 |
0.35 |
|
2018 |
Park S, Cui J, Yu WA, Wu L, Carmon K, Liu QJ. Differential activities and mechanisms of the four R-Spondins in potentiating Wnt/β-catenin signaling. The Journal of Biological Chemistry. PMID 29752411 DOI: 10.1074/Jbc.Ra118.002743 |
0.563 |
|
2018 |
Azhdarinia A, Voss J, Ghosh SC, Simien JA, Hernandez Vargas S, Cui J, Yu WA, Liu Q, Carmon KS. Evaluation of anti-LGR5 Antibodies by ImmunoPET for Imaging Colorectal Tumors and Development of Antibody-Drug Conjugates. Molecular Pharmaceutics. PMID 29718672 DOI: 10.1021/Acs.Molpharmaceut.8B00275 |
0.353 |
|
2017 |
Carmon KS, Gong X, Yi J, Wu L, Thomas A, Moore CM, Masuho I, Timson DJ, Martemyanov KA, Liu QJ. LGR5 receptor promotes cell-cell adhesion in stem cells and colon cancer cells via the IQGAP1 -Rac1 pathway. The Journal of Biological Chemistry. PMID 28739799 DOI: 10.1074/Jbc.M117.786798 |
0.446 |
|
2017 |
Carmon KS, Lin Q, Gong X, Thomas A, Liu Q. Correction for Carmon et al., "LGR5 Interacts and Cointernalizes with Wnt Receptors To Modulate Wnt/β-Catenin Signaling". Molecular and Cellular Biology. 37. PMID 28620019 DOI: 10.1128/Mcb.00203-17 |
0.402 |
|
2016 |
Gong X, Azhdarinia A, Ghosh SC, Xiong W, An Z, Liu Q, Carmon KS. LGR5-targeted antibody-drug conjugate eradicates gastrointestinal tumors and prevents recurrence. Molecular Cancer Therapeutics. PMID 27207778 DOI: 10.1158/1535-7163.Mct-16-0114 |
0.404 |
|
2014 |
Gong X, Yi J, Carmon KS, Crumbley CA, Xiong W, Thomas A, Fan X, Guo S, An Z, Chang JT, Liu QJ. Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness. Oncogene. PMID 25531322 DOI: 10.1038/Onc.2014.417 |
0.436 |
|
2014 |
Carmon KS, Gong X, Yi J, Thomas A, Liu Q. RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: E1221-9. PMID 24639526 DOI: 10.1073/Pnas.1323106111 |
0.57 |
|
2012 |
Gong X, Carmon KS, Lin Q, Thomas A, Yi J, Liu Q. LGR6 is a high affinity receptor of R-spondins and potentially functions as a tumor suppressor. Plos One. 7: e37137. PMID 22615920 DOI: 10.1371/Journal.Pone.0037137 |
0.476 |
|
2012 |
Carmon KS, Lin Q, Gong X, Thomas A, Liu Q. LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β-catenin signaling. Molecular and Cellular Biology. 32: 2054-64. PMID 22473993 DOI: 10.1128/Mcb.00272-12 |
0.53 |
|
2011 |
Carmon KS, Gong X, Lin Q, Thomas A, Liu Q. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proceedings of the National Academy of Sciences of the United States of America. 108: 11452-7. PMID 21693646 DOI: 10.1073/Pnas.1106083108 |
0.517 |
|
2011 |
Carmon KS, Loose DS. SFRP4 (Secreted Frizzled -Related Protein 4) Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/44714 |
0.562 |
|
2010 |
Carmon KS, Loose DS. Development of a bioassay for detection of Wnt-binding affinities for individual frizzled receptors. Analytical Biochemistry. 401: 288-94. PMID 20227380 DOI: 10.1016/J.Ab.2010.03.009 |
0.661 |
|
2008 |
Carmon KS, Loose DS. Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells. Molecular Cancer Research : McR. 6: 1017-28. PMID 18567805 DOI: 10.1158/1541-7786.Mcr-08-0039 |
0.664 |
|
2008 |
Carmon KS, Loose DS. Wnt7a interaction with Fzd5 and detection of signaling activation using a split eGFP. Biochemical and Biophysical Research Communications. 368: 285-91. PMID 18230341 DOI: 10.1016/J.Bbrc.2008.01.088 |
0.656 |
|
2007 |
Baltus RE, Carmon KS, Luck LA. Quartz crystal microbalance (QCM) with immobilized protein receptors: comparison of response to ligand binding for direct protein immobilization and protein attachment via disulfide linker. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 3880-5. PMID 17323983 DOI: 10.1021/La0628468 |
0.409 |
|
2005 |
Carmon KS, Baltus RE, Luck LA. A biosensor for estrogenic substances using the quartz crystal microbalance. Analytical Biochemistry. 345: 277-83. PMID 16125128 DOI: 10.1016/J.Ab.2005.07.018 |
0.344 |
|
2005 |
Wang J, Carmon KS, Luck LA, Suni II. Electrochemical impedance biosensor for glucose detection utilizing a periplasmic E. coli receptor protein Electrochemical and Solid-State Letters. 8. DOI: 10.1149/1.1943549 |
0.343 |
|
2004 |
Carmon KS, Baltus RE, Luck LA. A piezoelectric quartz crystal biosensor: the use of two single cysteine mutants of the periplasmic Escherichia coli glucose/galactose receptor as target proteins for the detection of glucose. Biochemistry. 43: 14249-56. PMID 15518575 DOI: 10.1021/Bi0484623 |
0.348 |
|
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