Year |
Citation |
Score |
2024 |
Riddle RC, Choquette GM. Serine synthesis promotes bone degradation. Nature Metabolism. 6: 8-9. PMID 38200113 DOI: 10.1038/s42255-023-00949-x |
0.357 |
|
2023 |
Gao CW, Lin W, Riddle RC, Kushwaha P, Boukas L, Björnsson HT, Hansen KD, Fahrner JA. A mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition. Jci Insight. PMID 38015625 DOI: 10.1172/jci.insight.173392 |
0.356 |
|
2023 |
Sarver DC, Garcia-Diaz J, Riddle RC, Wong GW. Tmem263 deletion disrupts the GH/IGF-1 axis and causes dwarfism and impairs skeletal acquisition. Biorxiv : the Preprint Server For Biology. PMID 37577461 DOI: 10.1101/2023.08.02.551694 |
0.315 |
|
2023 |
Kim SP, Seward AH, Garcia-Diaz J, Alekos N, Gould NR, Aja S, Stains JP, Wolfgang MJ, Riddle RC. Peroxisome proliferator activated receptor-γ in osteoblasts controls bone formation and fat mass by regulating sclerostin expression. Iscience. 26: 106999. PMID 37534168 DOI: 10.1016/j.isci.2023.106999 |
0.371 |
|
2023 |
Gao CW, Lin W, Riddle RC, Kushwaha P, Boukas L, Björnsson HT, Hansen KD, Fahrner JA. Novel mouse model of Weaver syndrome displays overgrowth and excess osteogenesis reversible with KDM6A/6B inhibition. Biorxiv : the Preprint Server For Biology. PMID 37425751 DOI: 10.1101/2023.06.23.546270 |
0.357 |
|
2023 |
Alekos N, Kushwaha P, Kim S, Li Z, Abood A, Dirckx N, Aja S, Kodama J, Garcia-Diaz J, Otsuru S, Rendina-Ruedy E, Wolfgang MJ, Riddle RC. Mitochondrial B-oxidation of adipose-derived fatty acids by osteoblast fuels parathyroid hormone-induced bone formation. Jci Insight. PMID 36729662 DOI: 10.1172/jci.insight.165604 |
0.381 |
|
2023 |
Riddle RC. Endocrine Functions of Sclerostin. Current Opinion in Endocrine and Metabolic Research. 28. PMID 36713826 DOI: 10.1016/j.coemr.2022.100433 |
0.348 |
|
2022 |
Dirckx N, Zhang Q, Chu EY, Tower RJ, Li Z, Guo S, Yuan S, Khare PA, Zhang C, Verardo A, Alejandro LO, Park A, Faugere MC, Helfand SL, Somerman MJ, ... Riddle RC, et al. A specialized metabolic pathway partitions citrate in hydroxyapatite to impact mineralization of bones and teeth. Proceedings of the National Academy of Sciences of the United States of America. 119: e2212178119. PMID 36322718 DOI: 10.1073/pnas.2212178119 |
0.395 |
|
2022 |
Kushwaha P, Alekos NS, Kim SP, Li Z, Wolfgang MJ, Riddle RC. Mitochondrial fatty acid β-oxidation is important for normal osteoclast formation in growing female mice. Frontiers in Physiology. 13: 997358. PMID 36187756 DOI: 10.3389/fphys.2022.997358 |
0.366 |
|
2022 |
Kim SP, Li Z, Riddle RC. Evaluation of Fatty Acid Oxidation in Cultured Bone Cells. Journal of Visualized Experiments : Jove. PMID 35575521 DOI: 10.3791/63638 |
0.36 |
|
2022 |
Fulzele K, Riddle RC, DiGirolamo DJ, Cao X, Wan C, Chen D, Faugere MC, Aja S, Hussain MA, Brüning JC, Clemens TL. Insulin Receptor Signaling in Osteoblasts Regulates Postnatal Bone Acquisition and Body Composition. Cell. 185: 746. PMID 35180388 DOI: 10.1016/j.cell.2022.01.016 |
0.348 |
|
2021 |
Kim SP, Da H, Wang L, Taketo MM, Wan M, Riddle RC. Bone-derived sclerostin and Wnt/β-catenin signaling regulate PDGFRα adipoprogenitor cell differentiation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21957. PMID 34606641 DOI: 10.1096/fj.202100691R |
0.456 |
|
2021 |
Kushwaha P, Khambadkone SG, Li M, Goodman EJ, Aravindan N, Riddle RC, Tamashiro KLK. Maternal High-Fat Diet Induces Long-Lasting Defects in Bone Structure in Rat Offspring Through Enhanced Osteoclastogenesis. Calcified Tissue International. PMID 33386478 DOI: 10.1007/s00223-020-00801-4 |
0.313 |
|
2020 |
Yoo S, Cha D, Kim S, Jiang L, Cooke P, Adebesin M, Wolfe A, Riddle R, Aja S, Blackshaw S. Tanycyte ablation in the arcuate nucleus and median eminence increases obesity susceptibility by increasing body fat content in male mice. Glia. PMID 32173924 DOI: 10.1002/Glia.23817 |
0.309 |
|
2020 |
Kushwaha P, Kim S, Foxa GE, Michalski MN, Williams BO, Tomlinson RE, Riddle RC. Frizzled-4 is required for normal bone acquisition despite compensation by Frizzled-8. Journal of Cellular Physiology. PMID 31985040 DOI: 10.1002/Jcp.29563 |
0.512 |
|
2019 |
Youngstrom DW, Zondervan RL, Doucet NR, Acevedo PK, Sexton HE, Gardner EA, Anderson JS, Kushwaha P, Little HC, Rodriguez S, Riddle RC, Kalajzic I, William Wong G, Hankenson KD. CTRP3 regulates endochondral ossification and bone remodeling during fracture healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 31808575 DOI: 10.1002/Jor.24553 |
0.379 |
|
2019 |
Fahrner JA, Lin WY, Riddle RC, Boukas L, DeLeon VB, Chopra S, Lad SE, Luperchio TR, Hansen KD, Bjornsson HT. Precocious chondrocyte differentiation disrupts skeletal growth in Kabuki Syndrome mice. Jci Insight. PMID 31557133 DOI: 10.1172/Jci.Insight.129380 |
0.392 |
|
2019 |
Dirckx N, Moorer MC, Clemens TL, Riddle RC. The role of osteoblasts in energy homeostasis. Nature Reviews. Endocrinology. PMID 31462768 DOI: 10.1038/S41574-019-0246-Y |
0.5 |
|
2019 |
Zhang Q, Riddle RC, Yang Q, Rosen CR, Guttridge DC, Dirckx N, Faugere MC, Farber CR, Clemens TL. The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage. Proceedings of the National Academy of Sciences of the United States of America. PMID 31434789 DOI: 10.1073/Pnas.1905489116 |
0.463 |
|
2019 |
Rindone AN, Kachniarz B, Achebe CC, Riddle RC, O'Sullivan AN, Dorafshar AH, Grayson WL. Heparin-Conjugated Decellularized Bone Particles Promote Enhanced Osteogenic Signaling of PDGF-BB to Adipose-Derived Stem Cells in Tissue Engineered Bone Grafts. Advanced Healthcare Materials. e1801565. PMID 30941920 DOI: 10.1002/Adhm.201801565 |
0.476 |
|
2019 |
Kim SP, Da H, Li Z, Kushwaha P, Beil C, Mei L, Xiong WC, Wolfgang MJ, Clemens TL, Riddle RC. Lrp4 expression by adipocytes and osteoblasts differentially impacts sclerostin's endocrine effects on body composition and glucose metabolism. The Journal of Biological Chemistry. PMID 30842262 DOI: 10.1074/Jbc.Ra118.006769 |
0.451 |
|
2019 |
Rindone AN, Kachniarz B, Achebe CC, Riddle RC, O'Sullivan AN, Dorafshar AH, Grayson WL. Craniofacial Bone‐Tissue Engineering: Heparin‐Conjugated Decellularized Bone Particles Promote Enhanced Osteogenic Signaling of PDGF‐BB to Adipose‐Derived Stem Cells in Tissue Engineered Bone Grafts (Adv. Healthcare Mater. 10/2019) Advanced Healthcare Materials. 8: 1970042. DOI: 10.1002/Adhm.201970042 |
0.447 |
|
2018 |
Moorer MC, Riddle RC. Regulation of Osteoblast Metabolism by Wnt Signaling. Endocrinology and Metabolism (Seoul, Korea). PMID 30112869 DOI: 10.3803/Enm.2018.33.3.318 |
0.447 |
|
2017 |
Kim SP, Frey JL, Li Z, Kushwaha P, Zoch ML, Tomlinson RE, Da H, Aja S, Noh HL, Kim JK, Hussain MA, Thorek DLJ, Wolfgang MJ, Riddle RC. Sclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytes. Proceedings of the National Academy of Sciences of the United States of America. PMID 29229807 DOI: 10.1073/Pnas.1707876115 |
0.413 |
|
2017 |
Frey JL, Kim SP, Li Z, Wolfgang MJ, Riddle RC. β-catenin directs long-chain fatty acid catabolism in the osteoblasts of male mice. Endocrinology. PMID 29077850 DOI: 10.1210/En.2017-00850 |
0.396 |
|
2017 |
Kim SP, Frey JL, Li Z, Goh BC, Riddle RC. Lack of Lrp5 signaling in osteoblasts sensitizes male mice to diet-induced disturbances in glucose metabolism. Endocrinology. PMID 28938444 DOI: 10.1210/En.2017-00657 |
0.405 |
|
2017 |
Kushwaha P, Wolfgang MJ, Riddle RC. Fatty acid metabolism by the osteoblast. Bone. PMID 28863948 DOI: 10.1016/J.Bone.2017.08.024 |
0.367 |
|
2017 |
Kim SP, Li Z, Zoch ML, Frey JL, Bowman CE, Kushwaha P, Ryan KA, Goh BC, Scafidi S, Pickett JE, Faugere MC, Kershaw EE, Thorek DLJ, Clemens TL, Wolfgang MJ, ... Riddle RC, et al. Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner. Jci Insight. 2. PMID 28814665 DOI: 10.1172/Jci.Insight.92704 |
0.438 |
|
2017 |
Ziegler SG, Ferreira CR, MacFarlane EG, Riddle RC, Tomlinson RE, Chew EY, Martin L, Ma CT, Sergienko E, Pinkerton AB, Millán JL, Gahl WA, Dietz HC. Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase. Science Translational Medicine. 9. PMID 28592560 DOI: 10.1126/Scitranslmed.Aal1669 |
0.385 |
|
2017 |
Tomlinson RE, Li Z, Li Z, Minichiello L, Riddle RC, Venkatesan A, Clemens TL. NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416686 DOI: 10.1073/Pnas.1701054114 |
0.455 |
|
2017 |
Riddle RC, Clemens TL. Bone Cell Bioenergetics and Skeletal Energy Homeostasis. Physiological Reviews. 97: 667-698. PMID 28202599 DOI: 10.1152/Physrev.00022.2016 |
0.437 |
|
2016 |
Li Z, Frey JL, Wong GW, Faugere MC, Wolfgang MJ, Kim JK, Riddle RC, Clemens TL. Glucose Transporter-4 Facilitates Insulin-stimulated Glucose Uptake in Osteoblasts. Endocrinology. en20161583. PMID 27689415 DOI: 10.1210/En.2016-1583 |
0.368 |
|
2016 |
Zoch ML, Abou DS, Clemens TL, Thorek DL, Riddle RC. In vivo radiometric analysis of glucose uptake and distribution in mouse bone. Bone Research. 4: 16004. PMID 27088042 DOI: 10.1038/Boneres.2016.4 |
0.454 |
|
2016 |
Abou DS, Ulmert D, Doucet M, Hobbs RF, Riddle RC, Thorek DL. Whole-Body and Microenvironmental Localization of Radium-223 in Naïve and Mouse Models of Prostate Cancer Metastasis. Journal of the National Cancer Institute. 108. PMID 26683407 DOI: 10.1093/Jnci/Djv380 |
0.329 |
|
2016 |
Zoch ML, Clemens TL, Riddle RC. New insights into the biology of osteocalcin. Bone. 82: 42-9. PMID 26055108 DOI: 10.1016/J.Bone.2015.05.046 |
0.488 |
|
2015 |
Riddle RC. Parathyroid Hormone Reprograms Osteoblast Metabolism. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 30: 1956-8. PMID 26448640 DOI: 10.1002/Jbmr.2727 |
0.301 |
|
2015 |
Frey JL, Li Z, Ellis JM, Zhang Q, Farber CR, Aja S, Wolfgang MJ, Clemens TL, Riddle RC. Wnt-Lrp5 signaling regulates fatty acid metabolism in the osteoblast. Molecular and Cellular Biology. 35: 1979-91. PMID 25802278 DOI: 10.1128/Mcb.01343-14 |
0.496 |
|
2015 |
Zhang Q, Riddle RC, Clemens TL. Bone and the regulation of global energy balance. Journal of Internal Medicine. 277: 681-9. PMID 25597336 DOI: 10.1111/Joim.12348 |
0.521 |
|
2015 |
Kanazawa I, Canaff L, Abi Rafeh J, Angrula A, Li J, Riddle RC, Boraschi-Diaz I, Komarova SV, Clemens TL, Murshed M, Hendy GN. Osteoblast menin regulates bone mass in vivo. The Journal of Biological Chemistry. 290: 3910-24. PMID 25538250 DOI: 10.1074/Jbc.M114.629899 |
0.485 |
|
2015 |
Abou D, Ulmert D, Hobbs R, Riddle R, Thorek D. MP46-19 MICRODISTRIBUTION OF ALPHA PARTICLE EMITTING RADIUM-223 DICHLORIDE IN MODELS OF PROSTATE CANCER BONE METASTASIS Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.1582 |
0.408 |
|
2014 |
Frey JL, Stonko DP, Faugere MC, Riddle RC. Hypoxia-inducible factor-1α restricts the anabolic actions of parathyroid hormone. Bone Research. 2: 14005. PMID 26273518 DOI: 10.1038/Boneres.2014.5 |
0.454 |
|
2014 |
Riddle RC, Clemens TL. Insulin, osteoblasts, and energy metabolism: why bone counts calories. The Journal of Clinical Investigation. 124: 1465-7. PMID 24642463 DOI: 10.1172/Jci75554 |
0.391 |
|
2014 |
Riddle RC, Frey JL, Tomlinson RE, Ferron M, Li Y, DiGirolamo DJ, Faugere MC, Hussain MA, Karsenty G, Clemens TL. Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis. Molecular and Cellular Biology. 34: 1850-62. PMID 24591652 DOI: 10.1128/Mcb.00075-14 |
0.467 |
|
2013 |
Riddle RC, Diegel CR, Leslie JM, Van Koevering KK, Faugere MC, Clemens TL, Williams BO. Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition. Plos One. 8: e63323. PMID 23675479 DOI: 10.1371/Journal.Pone.0063323 |
0.525 |
|
2013 |
Zhang Y, Chin-Quee K, Riddle RC, Li Z, Zhou Z, Donahue HJ. BRMS1 Sensitizes Breast Cancer Cells to ATP-Induced Growth Suppression. Bioresearch Open Access. 2: 77-83. PMID 23593560 DOI: 10.1089/Biores.2012.0260 |
0.541 |
|
2013 |
Bogan R, Riddle RC, Li Z, Kumar S, Nandal A, Faugere MC, Boskey A, Crawford SE, Clemens TL. A mouse model for human osteogenesis imperfecta type VI. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1531-6. PMID 23413146 DOI: 10.1002/Jbmr.1892 |
0.482 |
|
2011 |
Riddle RC, Leslie JM, Gross TS, Clemens TL. Hypoxia-inducible factor-1α protein negatively regulates load-induced bone formation. The Journal of Biological Chemistry. 286: 44449-56. PMID 22081627 DOI: 10.1074/Jbc.M111.276683 |
0.456 |
|
2010 |
Mavalli MD, DiGirolamo DJ, Fan Y, Riddle RC, Campbell KS, van Groen T, Frank SJ, Sperling MA, Esser KA, Bamman MM, Clemens TL. Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice. The Journal of Clinical Investigation. 120: 4007-20. PMID 20921627 DOI: 10.1172/Jci42447 |
0.311 |
|
2010 |
Riddle RC, Lakhanpal A, Clemens TL. Roles of vessel growth factors in bone development and repair. Joint, Bone, Spine : Revue Du Rhumatisme. 77: 517-8. PMID 20851027 DOI: 10.1016/J.Jbspin.2010.08.007 |
0.419 |
|
2010 |
Fulzele K, Riddle RC, DiGirolamo DJ, Cao X, Wan C, Chen D, Faugere MC, Aja S, Hussain MA, Brüning JC, Clemens TL. Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition. Cell. 142: 309-19. PMID 20655471 DOI: 10.1016/J.Cell.2010.06.002 |
0.461 |
|
2010 |
Wan C, Shao J, Gilbert SR, Riddle RC, Long F, Johnson RS, Schipani E, Clemens TL. Role of HIF-1alpha in skeletal development. Annals of the New York Academy of Sciences. 1192: 322-6. PMID 20392254 DOI: 10.1111/J.1749-6632.2009.05238.X |
0.471 |
|
2010 |
Shomento SH, Wan C, Cao X, Faugere MC, Bouxsein ML, Clemens TL, Riddle RC. Hypoxia-inducible factors 1alpha and 2alpha exert both distinct and overlapping functions in long bone development. Journal of Cellular Biochemistry. 109: 196-204. PMID 19899108 DOI: 10.1002/Jcb.22396 |
0.384 |
|
2010 |
Riddle RC, Lakhanpal A, Clemens TL. Roles of vascular growth factors in bone development and repair | Rôles des facteurs de croissance vasculaires dans le développement et la réparation des os Revue Du Rhumatisme (Edition Francaise). 77: A33-A35. DOI: 10.1016/J.Rhum.2010.07.003 |
0.316 |
|
2009 |
Riddle RC, Khatri R, Schipani E, Clemens TL. Role of hypoxia-inducible factor-1alpha in angiogenic-osteogenic coupling. Journal of Molecular Medicine (Berlin, Germany). 87: 583-90. PMID 19415227 DOI: 10.1007/S00109-009-0477-9 |
0.445 |
|
2009 |
Riddle RC, Donahue HJ. From streaming-potentials to shear stress: 25 years of bone cell mechanotransduction. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 143-9. PMID 18683882 DOI: 10.1002/Jor.20723 |
0.69 |
|
2008 |
Riddle RC, Taylor AF, Donahue HJ. Fluid flow assays. Methods in Molecular Biology (Clifton, N.J.). 455: 335-45. PMID 18463829 DOI: 10.1007/978-1-59745-104-8_23 |
0.687 |
|
2008 |
Riddle RC, Hippe KR, Donahue HJ. Chemotransport contributes to the effect of oscillatory fluid flow on human bone marrow stromal cell proliferation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 918-24. PMID 18327808 DOI: 10.1002/Jor.20637 |
0.662 |
|
2007 |
Riddle RC, Taylor AF, Rogers JR, Donahue HJ. ATP release mediates fluid flow-induced proliferation of human bone marrow stromal cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 589-600. PMID 17243863 DOI: 10.1359/Jbmr.070113 |
0.638 |
|
2006 |
Riddle RC, Taylor AF, Genetos DC, Donahue HJ. MAP kinase and calcium signaling mediate fluid flow-induced human mesenchymal stem cell proliferation. American Journal of Physiology. Cell Physiology. 290: C776-84. PMID 16267109 DOI: 10.1152/Ajpcell.00082.2005 |
0.689 |
|
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