Renjie Chai, Ph.D. - Publications

Affiliations: 
2009 Biomedical Studies Baylor University, Waco, TX 
Area:
Molecular Biology, Cell Biology

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Xu C, Zhang L, Zhou Y, Du H, Qi J, Tan F, Peng L, Gu X, Li N, Sun Q, Zhang Z, Lu Y, Qian X, Tong B, Sun J, ... Chai R, et al. Pcolce2 overexpression promotes supporting cell reprogramming in the neonatal mouse cochlea. Cell Proliferation. e13633. PMID 38528645 DOI: 10.1111/cpr.13633  0.462
2024 Hu Y, Xing J, Zhang H, Pang X, Zhai Y, Cheng H, Xu D, Liao M, Qi Y, Wu D, Zhang B, Cheng L, Chu B, Zhang C, Zhao Y, ... Chai R, et al. Electroacoustic responsive cochlea-on-a-chip. Advanced Materials (Deerfield Beach, Fla.). e2309002. PMID 38488690 DOI: 10.1002/adma.202309002  0.305
2024 Sun Q, Zhang L, Chen T, Li N, Tan F, Gu X, Zhou Y, Zhang Z, Lu Y, Lu J, Qian X, Guan B, Qi J, Ye F, Chai R. AAV-mediated Gpm6b expression supports hair cell reprogramming. Cell Proliferation. e13620. PMID 38400824 DOI: 10.1111/cpr.13620  0.53
2023 Ma X, Guo J, Tian M, Fu Y, Jiang P, Zhang Y, Chai R. Advance and Application of Single-cell Transcriptomics in Auditory Research. Neuroscience Bulletin. PMID 38015350 DOI: 10.1007/s12264-023-01149-z  0.322
2023 Qi J, Huang W, Lu Y, Yang X, Zhou Y, Chen T, Wang X, Yu Y, Sun JQ, Chai R. Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear. Neuroscience Bulletin. PMID 37787875 DOI: 10.1007/s12264-023-01130-w  0.512
2023 Cheng C, Qi J, Zhang L, Li H, Lu J, Li S, Zhang Z, Qiu Y, Zhang C, Jiang L, Yu C, Gao X, Bird PI, Chai R. Corrigendum to "Absence of Serpinb6a causes progressive hair cell apoptosis and hearing loss in mice" [Journal of Genetics and Genomics (2023) 50, 122-125]. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 50: 458. PMID 37330250 DOI: 10.1016/j.jgg.2023.04.011  0.301
2023 Cheng C, Ma J, Lu X, Zhang P, Wang X, Guo L, Li P, Wei Y, Li GL, Gao X, Zhang Y, Chai R, Li H, Sun S. P2X7 receptor is required for the ototoxicity caused by aminoglycoside in developing cochlear hair cells. Neurobiology of Disease. 106176. PMID 37263384 DOI: 10.1016/j.nbd.2023.106176  0.307
2023 Fu X, Wan P, Lu L, Wan Y, Liu Z, Hong G, Cao S, Bi X, Zhou J, Qiao R, Guo S, Xiao Y, Wang B, Chang M, Li W, ... ... Chai R, et al. Peroxisome Deficiency in Cochlear Hair Cells Causes Hearing Loss by Deregulating BK Channels. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2300402. PMID 37171794 DOI: 10.1002/advs.202300402  0.337
2023 Qian F, Wei G, Gao Y, Wang X, Gong J, Guo C, Wang X, Zhang X, Zhao J, Wang C, Xu M, Hu Y, Yin G, Kang J, Chai R, et al. Correction: Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss. Cellular and Molecular Life Sciences : Cmls. 80: 146. PMID 37169901 DOI: 10.1007/s00018-023-04780-1  0.392
2023 Yang X, Qi J, Zhang L, Tan F, Huang H, Xu C, Cui Y, Chai R, Wu P. The role of Espin in the stereocilia regeneration and protection in Atoh1-overexpressed cochlear epithelium. Cell Proliferation. e13483. PMID 37084708 DOI: 10.1111/cpr.13483  0.351
2023 Xu C, Qi J, Hu X, Zhang L, Sun Q, Li N, Chen X, Guo F, Wu P, Shi Y, Chai R. Rps14 upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea. Cell Proliferation. e13458. PMID 36977657 DOI: 10.1111/cpr.13458  0.602
2023 Zhang L, Fang Y, Tan F, Guo F, Zhang Z, Li N, Sun Q, Qi J, Chai R. AAV-Net1 facilitates the trans-differentiation of supporting cells into hair cells in the murine cochlea. Cellular and Molecular Life Sciences : Cmls. 80: 86. PMID 36917323 DOI: 10.1007/s00018-023-04743-6  0.548
2022 Xia M, Ma J, Wu M, Guo L, Chen Y, Li GL, Sun S, Chai R, Li H, Li W. Generation of innervated cochlear organoid recapitulates early development of auditory unit. Stem Cell Reports. PMID 36584686 DOI: 10.1016/j.stemcr.2022.11.024  0.427
2022 Zhang Z, Gao S, Hu YN, Chen X, Cheng C, Fu XL, Zhang SS, Wang XL, Che YW, Zhang C, Chai RJ. Ti C T MXene Composite 3D Hydrogel Potentiates mTOR Signaling to Promote the Generation of Functional Hair Cells in Cochlea Organoids. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2203557. PMID 36117048 DOI: 10.1002/advs.202203557  0.463
2022 Cheng C, Qi J, Zhang L, Li H, Lu J, Li S, Zhang Z, Qiu Y, Zhang C, Jiang L, Yu C, Gao X, Bird PI, Chai R. Absence of Serpinb6a causes progressive hair cell apoptosis and hearing loss in mice. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 36087923 DOI: 10.1016/j.jgg.2022.08.006  0.367
2022 Li Y, Hu Y, Wei H, Cao W, Qi Y, Zhou S, Zhang P, Li H, Li GL, Chai R. Two-dimensional TiCT MXene promotes electrophysiological maturation of neural circuits. Journal of Nanobiotechnology. 20: 398. PMID 36045382 DOI: 10.1186/s12951-022-01590-8  0.314
2022 Wu Y, Meng W, Guan M, Zhao X, Zhang C, Fang Q, Zhang Y, Sun Z, Cai M, Huang D, Yang X, Yu Y, Cui Y, He S, Chai R. Pitavastatin protects against neomycin-induced ototoxicity through inhibition of endoplasmic reticulum stress. Frontiers in Molecular Neuroscience. 15: 963083. PMID 35992197 DOI: 10.3389/fnmol.2022.963083  0.423
2022 Zhang Z, Chai R. Hear the sounds: The role of G Protein-Coupled Receptors in the cochlea. American Journal of Physiology. Cell Physiology. PMID 35938679 DOI: 10.1152/ajpcell.00453.2021  0.347
2022 Ding X, Hu Y, Cheng H, Zhang X, Lu L, Gao S, Cheng C, Wang L, Qian X, Zhang C, Chai R, Gao X, Huang Z. Graphene Substrates Promote the Differentiation of Inner Ear Lgr5+ Progenitor Cells Into Hair Cells. Frontiers in Bioengineering and Biotechnology. 10: 927248. PMID 35814013 DOI: 10.3389/fbioe.2022.927248  0.453
2022 Qian F, Wei G, Gao Y, Wang X, Gong J, Guo C, Wang X, Zhang X, Zhao J, Wang C, Xu M, Hu Y, Yin G, Kang J, Chai R, et al. Single-cell RNA-sequencing of zebrafish hair cells reveals novel genes potentially involved in hearing loss. Cellular and Molecular Life Sciences : Cmls. 79: 385. PMID 35753015 DOI: 10.1007/s00018-022-04410-2  0.536
2022 Zhang Y, Zhang S, Zhou H, Ma X, Wu L, Tian M, Li S, Qian X, Gao X, Chai R. Dync1li1 is required for the survival of mammalian cochlear hair cells by regulating the transportation of autophagosomes. Plos Genetics. 18: e1010232. PMID 35727824 DOI: 10.1371/journal.pgen.1010232  0.358
2022 Xia L, Zhang C, Su K, Fan J, Niu Y, Yu Y, Chai R. Oriented Growth of Neural Stem Cell-Derived Neurons Regulated by Magnetic Nanochains. Frontiers in Bioengineering and Biotechnology. 10: 895107. PMID 35677297 DOI: 10.3389/fbioe.2022.895107  0.331
2022 Ma X, Zhang S, Qin S, Guo J, Yuan J, Qiang R, Zhou S, Cao W, Yang J, Ma F, Chai R. Transcriptomic and epigenomic analyses explore the potential role of H3K4me3 in neomycin-induced cochlear Lgr5+ progenitor cell regeneration of hair cells. Human Cell. PMID 35668241 DOI: 10.1007/s13577-022-00727-z  0.562
2022 Zhang Q, Wu Y, Yu Y, Niu Y, Fang Q, Chen X, Qi J, Zhang C, Wu G, Su K, Chai R. Tetrandrine Prevents Neomycin-Induced Ototoxicity by Promoting Steroid Biosynthesis. Frontiers in Bioengineering and Biotechnology. 10: 876237. PMID 35519614 DOI: 10.3389/fbioe.2022.876237  0.331
2022 Zhang Y, Fang Q, Wang H, Qi J, Sun S, Liao M, Wu Y, Hu Y, Jiang P, Cheng C, Qian X, Tang M, Cao W, Xiang S, Zhang C, ... ... Chai R, et al. Increased mitophagy protects cochlear hair cells from aminoglycoside-induced damage. Autophagy. 1-17. PMID 35471096 DOI: 10.1080/15548627.2022.2062872  0.358
2022 Tao Y, Liu X, Yang L, Chu C, Tan F, Yu Z, Ke J, Li X, Zheng X, Zhao X, Qi J, Lin CP, Chai R, Zhong G, Wu H. AAV-ie-K558R mediated cochlear gene therapy and hair cell regeneration. Signal Transduction and Targeted Therapy. 7: 109. PMID 35449181 DOI: 10.1038/s41392-022-00938-8  0.511
2022 Li D, Hu Y, Wei H, Chen W, Liu Y, Yan X, Guo L, Liao M, Chen B, Chai R, Tang M. Superparamagnetic Iron Oxide Nanoparticles and Static Magnetic Field Regulate Neural Stem Cell Proliferation. Frontiers in Cellular Neuroscience. 15: 815280. PMID 35185472 DOI: 10.3389/fncel.2021.815280  0.307
2022 Wang M, Dong Y, Gao S, Zhong Z, Cheng C, Qiang R, Zhang Y, Shi X, Qian X, Gao X, Guan B, Yu C, Yu Y, Chai R. Hippo/YAP signaling pathway protects against neomycin-induced hair cell damage in the mouse cochlea. Cellular and Molecular Life Sciences : Cmls. 79: 79. PMID 35044530 DOI: 10.1007/s00018-021-04029-9  0.403
2021 He Z, Ding Y, Mu Y, Xu X, Kong W, Chai R, Chen X. Stem Cell-Based Therapies in Hearing Loss. Frontiers in Cell and Developmental Biology. 9: 730042. PMID 34746126 DOI: 10.3389/fcell.2021.730042  0.429
2021 Chen Y, Qiang R, Zhang Y, Cao W, Wu L, Jiang P, Ai J, Ma X, Dong Y, Gao X, Li H, Lu L, Zhang S, Chai R. The Expression and Roles of the Super Elongation Complex in Mouse Cochlear Lgr5+ Progenitor Cells. Frontiers in Cellular Neuroscience. 15: 735723. PMID 34658793 DOI: 10.3389/fncel.2021.735723  0.491
2021 Guo R, Liao M, Ma X, Hu Y, Qian X, Xiao M, Gao X, Chai R, Tang M. Cochlear implant-based electric-acoustic stimulation modulates neural stem cell-derived neural regeneration. Journal of Materials Chemistry. B. 9: 7793-7804. PMID 34586130 DOI: 10.1039/d1tb01029h  0.331
2021 Cheng C, Hou Y, Zhang Z, Wang Y, Lu L, Zhang L, Jiang P, Gao S, Fang Q, Zhu C, Gao J, Liu X, Xie W, Jia Z, Xu Z, ... ... Chai R, et al. Disruption of the autism-related gene Pak1 causes stereocilia disorganization, hair cell loss, and deafness in mice. Journal of Genetics and Genomics = Yi Chuan Xue Bao. PMID 34049799 DOI: 10.1016/j.jgg.2021.03.010  0.316
2021 He ZH, Li M, Fang QJ, Liao FL, Zou SY, Wu X, Sun HY, Zhao XY, Hu YJ, Xu XX, Chen S, Sun Y, Chai RJ, Kong WJ. FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathway. Autophagy. 1-22. PMID 34006186 DOI: 10.1080/15548627.2021.1916194  0.321
2021 Chen Y, Gu Y, Li Y, Li GL, Chai R, Li W, Li H. Generation of mature and functional hair cells by co-expression of Gfi1, Pou4f3, and Atoh1 in the postnatal mouse cochlea. Cell Reports. 35: 109016. PMID 33882317 DOI: 10.1016/j.celrep.2021.109016  0.361
2021 Yuan TF, Dong Y, Zhang L, Qi J, Yao C, Wang Y, Chai R, Liu Y, So KF. Neuromodulation-Based Stem Cell Therapy in Brain Repair: Recent Advances and Future Perspectives. Neuroscience Bulletin. PMID 33871821 DOI: 10.1007/s12264-021-00667-y  0.373
2020 Guo R, Xiao M, Zhao W, Zhou S, Hu Y, Liao M, Wang S, Yang X, Chai R, Tang M. 2D TiCT MXene couples electrical stimulation to promote proliferation and neural differentiation of neural stem cells. Acta Biomaterialia. PMID 33348061 DOI: 10.1016/j.actbio.2020.12.035  0.343
2020 Ding Y, Meng W, Kong W, He Z, Chai R. The Role of FoxG1 in the Inner Ear. Frontiers in Cell and Developmental Biology. 8: 614954. PMID 33344461 DOI: 10.3389/fcell.2020.614954  0.355
2020 Zhou H, Qian X, Xu N, Zhang S, Zhu G, Zhang Y, Liu D, Cheng C, Zhu X, Liu Y, Lu L, Tang J, Chai R, Gao X. Disruption of Atg7-dependent autophagy causes electromotility disturbances, outer hair cell loss, and deafness in mice. Cell Death & Disease. 11: 913. PMID 33099575 DOI: 10.1038/s41419-020-03110-8  0.333
2020 Zhang Y, Zhang S, Zhang Z, Dong Y, Ma X, Qiang R, Chen Y, Gao X, Zhao C, Chen F, He S, Chai R. Knockdown of in Sox9+ supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse utricle. Aging. 12. PMID 33099273 DOI: 10.18632/aging.104009  0.386
2020 Qian F, Wang X, Yin Z, Xie G, Yuan H, Liu D, Chai R. The gene is required for hair cell development in zebrafish. Aging. 12. PMID 33044947 DOI: 10.18632/aging.103840  0.354
2020 Zhong Z, Fu X, Li H, Chen J, Wang M, Gao S, Zhang L, Cheng C, Zhang Y, Li P, Zhang S, Qian X, Shu Y, Chai R, Gao X. Citicoline Protects Auditory Hair Cells Against Neomycin-Induced Damage. Frontiers in Cell and Developmental Biology. 8: 712. PMID 32984303 DOI: 10.3389/fcell.2020.00712  0.328
2020 Xia L, Shang Y, Chen X, Li H, Xu X, Liu W, Yang G, Wang T, Gao X, Chai R. Oriented Neural Spheroid Formation and Differentiation of Neural Stem Cells Guided by Anisotropic Inverse Opals. Frontiers in Bioengineering and Biotechnology. 8: 848. PMID 32850719 DOI: 10.3389/Fbioe.2020.00848  0.474
2020 Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Sun C, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D. THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. Plos Genetics. 16: e1008953. PMID 32776944 DOI: 10.1371/Journal.Pgen.1008953  0.49
2020 Yang Y, Zhang Y, Chai R, Gu Z. A Polydopamine-Functionalized Carbon Microfibrous Scaffold Accelerates the Development of Neural Stem Cells. Frontiers in Bioengineering and Biotechnology. 8: 616. PMID 32714901 DOI: 10.3389/Fbioe.2020.00616  0.473
2020 Zhang S, Qiang R, Dong Y, Zhang Y, Chen Y, Zhou H, Gao X, Chai R. Hair cell regeneration from inner ear progenitors in the mammalian cochlea. American Journal of Stem Cells. 9: 25-35. PMID 32699655  0.517
2020 Qi J, Zhang L, Tan F, Liu Y, Chu C, Zhu W, Wang Y, Qi Z, Chai R. Espin distribution as revealed by super-resolution microscopy of stereocilia. American Journal of Translational Research. 12: 130-141. PMID 32051742  0.343
2019 Li D, Yan X, Hu Y, Liu Y, Guo R, Liao M, Shao B, Tang Q, Guo X, Chai R, Zhang Q, Tang M. Two-Photon Image Tracking of Neural Stem Cells via Iridium Complexes Encapsulated in Polymeric Nanospheres. Acs Biomaterials Science & Engineering. 5: 1561-1568. PMID 33405629 DOI: 10.1021/Acsbiomaterials.8B01231  0.395
2019 Gao S, Cheng C, Wang M, Jiang P, Zhang L, Wang Y, Wu H, Zeng X, Wang H, Gao X, Ma Y, Chai R. Blebbistatin Inhibits Neomycin-Induced Apoptosis in Hair Cell-Like HEI-OC-1 Cells and in Cochlear Hair Cells. Frontiers in Cellular Neuroscience. 13: 590. PMID 32116554 DOI: 10.3389/Fncel.2019.00590  0.48
2019 Fang Q, Zhang Y, Chen X, Li H, Cheng L, Zhu W, Zhang Z, Tang M, Liu W, Wang H, Wang T, Shen T, Chai R. Three-Dimensional Graphene Enhances Neural Stem Cell Proliferation Through Metabolic Regulation. Frontiers in Bioengineering and Biotechnology. 7: 436. PMID 31998703 DOI: 10.3389/Fbioe.2019.00436  0.429
2019 Mei H, Mei D, Yu H, Sun S, Chen Y, Zhang Y, Chai R, Li H. Increased mitochondrial DNA copy number protects hair cells and HEI‑OC1 cells against drug‑induced apoptosis. Molecular Medicine Reports. PMID 31939628 DOI: 10.3892/Mmr.2019.10838  0.444
2019 Cheng C, Wang Y, Guo L, Lu X, Zhu W, Muhammad W, Zhang L, Lu L, Gao J, Tang M, Chen F, Gao X, Li H, Chai R. Age-related transcriptome changes in Sox2+ supporting cells in the mouse cochlea. Stem Cell Research & Therapy. 10: 365. PMID 31791390 DOI: 10.1186/S13287-019-1437-0  0.476
2019 Zhang Y, Li W, He Z, Wang Y, Shao B, Cheng C, Zhang S, Tang M, Qian X, Kong W, Wang H, Chai R, Gao X. Pre-treatment With Fasudil Prevents Neomycin-Induced Hair Cell Damage by Reducing the Accumulation of Reactive Oxygen Species. Frontiers in Molecular Neuroscience. 12: 264. PMID 31780893 DOI: 10.3389/Fnmol.2019.00264  0.468
2019 Fang QJ, Wu F, Chai R, Sha SH. Cochlear Surface Preparation in the Adult Mouse. Journal of Visualized Experiments : Jove. PMID 31762458 DOI: 10.3791/60299  0.562
2019 He ZH, Zou SY, Li M, Liao FL, Wu X, Sun HY, Zhao XY, Hu YJ, Li D, Xu XX, Chen S, Sun Y, Chai RJ, Kong WJ. The nuclear transcription factor FoxG1 affects the sensitivity of mimetic aging hair cells to inflammation by regulating autophagy pathways. Redox Biology. 28: 101364. PMID 31731101 DOI: 10.1016/J.Redox.2019.101364  0.469
2019 Zhang S, Zhang Y, Dong Y, Guo L, Zhang Z, Shao B, Qi J, Zhou H, Zhu W, Yan X, Hong G, Zhang L, Zhang X, Tang M, Zhao C, ... ... Chai R, et al. Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea. Cellular and Molecular Life Sciences : Cmls. PMID 31485717 DOI: 10.1007/s00018-019-03291-2  0.398
2019 Li G, Chen K, You D, Xia M, Li W, Fan S, Chai R, Zhang Y, Li H, Sun S. Laminin-Coated Electrospun Regenerated Silk Fibroin Mats Promote Neural Progenitor Cell Proliferation, Differentiation, and Survival . Frontiers in Bioengineering and Biotechnology. 7: 190. PMID 31448271 DOI: 10.3389/Fbioe.2019.00190  0.428
2019 Zhang S, Liu D, Dong Y, Zhang Z, Zhang Y, Zhou H, Guo L, Qi J, Qiang R, Tang M, Gao X, Zhao C, Chen X, Qian X, Chai R. Frizzled-9+ Supporting Cells Are Progenitors for the Generation of Hair Cells in the Postnatal Mouse Cochlea. Frontiers in Molecular Neuroscience. 12: 184. PMID 31427926 DOI: 10.3389/Fnmol.2019.00184  0.626
2019 Tan F, Chu C, Qi J, Li W, You D, Li K, Chen X, Zhao W, Cheng C, Liu X, Qiao Y, Su B, He S, Zhong C, Li H, ... Chai R, et al. AAV-ie enables safe and efficient gene transfer to inner ear cells. Nature Communications. 10: 3733. PMID 31427575 DOI: 10.1038/S41467-019-11687-8  0.391
2019 Zhao J, Tang M, Cao J, Ye D, Guo X, Xi J, Zhou Y, Xia Y, Qiao J, Chai R, Yang X, Kang J. Structurally Tunable Reduced Graphene Oxide Substrate Maintains Mouse Embryonic Stem Cell Pluripotency. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 6: 1802136. PMID 31380157 DOI: 10.1002/advs.201802136  0.36
2019 Tang M, Li J, He L, Guo R, Yan X, Li D, Zhang Y, Liao M, Shao B, Hu Y, Liu Y, Tang Q, Xia L, Guo X, Chai R. Transcriptomic profiling of neural stem cell differentiation on graphene substrates. Colloids and Surfaces. B, Biointerfaces. 182: 110324. PMID 31288132 DOI: 10.1016/J.Colsurfb.2019.06.054  0.378
2019 Wang J, Shen J, Guo L, Cheng C, Chai R, Shu Y, Li H. A humanized mouse model, demonstrating progressive hearing loss caused by MYO6 p.C442Y, is inherited in a semi-dominant pattern. Hearing Research. 379: 79-88. PMID 31103816 DOI: 10.1016/J.Heares.2019.04.014  0.384
2019 Liu Y, Qi J, Chen X, Tang M, Chu C, Zhu W, Li H, Tian C, Yang G, Zhong C, Zhang Y, Ni G, He S, Chai R, Zhong G. Critical role of spectrin in hearing development and deafness. Science Advances. 5: eaav7803. PMID 31001589 DOI: 10.1126/Sciadv.Aav7803  0.388
2019 Guo J, Chai R, Li H, Sun S. Protection of Hair Cells from Ototoxic Drug-Induced Hearing Loss. Advances in Experimental Medicine and Biology. 1130: 17-36. PMID 30915699 DOI: 10.1007/978-981-13-6123-4_2  0.444
2019 Chen Y, Zhang S, Chai R, Li H. Hair Cell Regeneration. Advances in Experimental Medicine and Biology. 1130: 1-16. PMID 30915698 DOI: 10.1007/978-981-13-6123-4_1  0.611
2019 Fang Q, Zhang Y, Da P, Shao B, Pan H, He Z, Cheng C, Li D, Guo J, Wu X, Guan M, Liao M, Zhang Y, Sha S, Zhou Z, ... ... Chai R, et al. Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Scientific Reports. 9: 3357. PMID 30833597 DOI: 10.1038/S41598-019-39769-Z  0.398
2019 Gu X, Chai R, Guo L, Dong B, Li W, Shu Y, Huang X, Li H. Transduction of Adeno-Associated Virus Vectors Targeting Hair Cells and Supporting Cells in the Neonatal Mouse Cochlea. Frontiers in Cellular Neuroscience. 13: 8. PMID 30733670 DOI: 10.3389/Fncel.2019.00008  0.543
2018 Li A, You D, Li W, Cui Y, He Y, Li W, Chen Y, Feng X, Sun S, Chai R, Li H. Novel compounds protect auditory hair cells against gentamycin-induced apoptosis by maintaining the expression level of H3K4me2. Drug Delivery. 25: 1033-1043. PMID 30799660 DOI: 10.1080/10717544.2018.1461277  0.385
2018 Chai R, Li GL, Wang J, Huang H. Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells 2018. Neural Plasticity. 2018: 4759135. PMID 30647730 DOI: 10.1155/2018/4759135  0.465
2018 Xie Y, Wang D, Lan F, Wei G, Ni T, Chai R, Liu D, Hu S, Li M, Li D, Wang H, Wang Y. Author Correction: An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells. Scientific Reports. 8: 17900. PMID 30538257 DOI: 10.1038/S41598-018-36738-W  0.343
2018 He Z, Fang Q, Li H, Shao B, Zhang Y, Zhang Y, Han X, Guo R, Cheng C, Guo L, Shi L, Li A, Yu C, Kong W, Zhao C, ... ... Chai R, et al. The role of FOXG1 in the postnatal development and survival of mouse cochlear hair cells. Neuropharmacology. PMID 30336149 DOI: 10.1016/j.neuropharm.2018.10.021  0.315
2018 Zhu C, Cheng C, Wang Y, Muhammad W, Liu S, Zhu W, Shao B, Zhang Z, Yan X, He Q, Xu Z, Yu C, Qian X, Lu L, Zhang S, ... ... Chai R, et al. Loss of ARHGEF6 Causes Hair Cell Stereocilia Deficits and Hearing Loss in Mice. Frontiers in Molecular Neuroscience. 11: 362. PMID 30333726 DOI: 10.3389/Fnmol.2018.00362  0.456
2018 Fu X, Sun X, Zhang L, Jin Y, Chai R, Yang L, Zhang A, Liu X, Bai X, Li J, Wang H, Gao J. Tuberous sclerosis complex-mediated mTORC1 overactivation promotes age-related hearing loss. The Journal of Clinical Investigation. PMID 30247156 DOI: 10.1172/Jci98058  0.473
2018 Yu Z, Jiang K, Xu Z, Huang H, Qian N, Lu Z, Chen D, Di R, Yuan T, Du Z, Xie W, Lu X, Li H, Chai R, Yang Y, et al. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration. Cell Stem Cell. PMID 30122476 DOI: 10.1016/J.Stem.2018.07.016  0.525
2018 Li H, Song Y, He Z, Chen X, Wu X, Li X, Bai X, Liu W, Li B, Wang S, Han Y, Xu L, Zhang D, Li J, Chai R, et al. Meclofenamic Acid Reduces Reactive Oxygen Species Accumulation and Apoptosis, Inhibits Excessive Autophagy, and Protects Hair Cell-Like HEI-OC1 Cells From Cisplatin-Induced Damage. Frontiers in Cellular Neuroscience. 12: 139. PMID 29875633 DOI: 10.3389/Fncel.2018.00139  0.453
2018 Zhang Y, Guo L, Lu X, Cheng C, Sun S, Li W, Zhao L, Lai C, Zhang S, Yu C, Tang M, Chen Y, Chai R, Li H. Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea. Frontiers in Molecular Neuroscience. 11: 147. PMID 29867341 DOI: 10.3389/Fnmol.2018.00147  0.618
2018 You D, Guo L, Li W, Sun S, Chen Y, Chai R, Li H. Characterization of Wnt and Notch-Responsive Lgr5+ Hair Cell Progenitors in the Striolar Region of the Neonatal Mouse Utricle. Frontiers in Molecular Neuroscience. 11: 137. PMID 29760650 DOI: 10.3389/Fnmol.2018.00137  0.569
2018 Liu W, Xu X, Fan Z, Sun G, Han Y, Zhang D, Xu L, Wang M, Wang X, Zhang S, Tang M, Li J, Chai R, Wang H. Wnt signaling activates TIGAR and protects against cisplatin-induced spiral ganglion neuron damage in the mouse cochlea. Antioxidants & Redox Signaling. PMID 29587485 DOI: 10.1089/Ars.2017.7288  0.412
2017 Chen Y, Lu X, Guo L, Ni W, Zhang Y, Zhao L, Wu L, Sun S, Zhang S, Tang M, Li W, Chai R, Li H. Hedgehog Signaling Promotes the Proliferation and Subsequent Hair Cell Formation of Progenitor Cells in the Neonatal Mouse Cochlea. Frontiers in Molecular Neuroscience. 10: 426. PMID 29311816 DOI: 10.3389/Fnmol.2017.00426  0.611
2017 Wang Y, Li J, Yao X, Li W, Du H, Tang M, Xiong W, Chai R, Xu Z. Loss of CIB2 Causes Profound Hearing Loss and Abolishes Mechanoelectrical Transduction in Mice. Frontiers in Molecular Neuroscience. 10: 401. PMID 29255404 DOI: 10.3389/Fnmol.2017.00401  0.444
2017 He Z, Guo L, Shu Y, Fang Q, Zhou H, Liu Y, Liu D, Lu L, Zhang X, Ding X, Liu D, Tang M, Kong W, Sha S, Li H, ... ... Chai R, et al. Autophagy protects auditory hair cells against neomycin-induced damage. Autophagy. 1-21. PMID 28968134 DOI: 10.1080/15548627.2017.1359449  0.384
2017 He Y, Lu X, Qian F, Liu D, Chai R, Li H. Insm1a Is Required for Zebrafish Posterior Lateral Line Development. Frontiers in Molecular Neuroscience. 10: 241. PMID 28824372 DOI: 10.3389/Fnmol.2017.00241  0.533
2017 Pan H, Song Q, Huang Y, Wang J, Chai R, Yin S, Wang J. Auditory Neuropathy after Damage to Cochlear Spiral Ganglion Neurons in Mice Resulting from Conditional Expression of Diphtheria Toxin Receptors. Scientific Reports. 7: 6409. PMID 28743950 DOI: 10.1038/S41598-017-06600-6  0.375
2017 Zhang S, Zhang Y, Yu P, Hu Y, Zhou H, Guo L, Xu X, Zhu X, Waqas M, Qi J, Zhang X, Liu Y, Chen F, Tang M, Qian X, ... ... Chai R, et al. Characterization of Lgr5+ Progenitor Cell Transcriptomes after Neomycin Injury in the Neonatal Mouse Cochlea. Frontiers in Molecular Neuroscience. 10: 213. PMID 28725177 DOI: 10.3389/Fnmol.2017.00213  0.492
2017 Chen Q, Quan Y, Wang N, Xie C, Ji Z, He H, Chai R, Li H, Yin S, Chin YE, Wei X, Gao WQ. Inactivation of STAT3 Signaling Impairs Hair Cell Differentiation in the Developing Mouse Cochlea. Stem Cell Reports. PMID 28669599 DOI: 10.1016/J.Stemcr.2017.05.031  0.603
2017 Waqas M, Sun S, Xuan C, Fang Q, Zhang X, Islam IU, Qi J, Zhang S, Gao X, Tang M, Shi H, Li H, Chai R. Bone morphogenetic protein 4 promotes the survival and preserves the structure of flow-sorted Bhlhb5+ cochlear spiral ganglion neurons in vitro. Scientific Reports. 7: 3506. PMID 28615657 DOI: 10.1038/S41598-017-03810-W  0.409
2017 Xie Y, Wang D, Lan F, Wei G, Ni T, Chai R, Liu D, Hu S, Li M, Li D, Wang H, Wang Y. An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells. Scientific Reports. 7: 2320. PMID 28539611 DOI: 10.1038/S41598-017-02456-Y  0.373
2017 Yu S, Cai X, Wu C, Liu Y, Zhang J, Gong X, Wang X, Wu X, Zhu T, Mo L, Gu J, Yu Z, Chen J, Thiery JP, Chai R, et al. Targeting HSP90-HDAC6 Regulating Network Implicates Precision Treatment of Breast Cancer. International Journal of Biological Sciences. 13: 505-517. PMID 28529458 DOI: 10.7150/Ijbs.18834  0.32
2017 Cheng C, Guo L, Lu L, Xu X, Zhang S, Gao J, Waqas M, Zhu C, Chen Y, Zhang X, Xuan C, Gao X, Tang M, Chen F, Shi H, ... ... Chai R, et al. Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea. Frontiers in Molecular Neuroscience. 10: 122. PMID 28491023 DOI: 10.3389/Fnmol.2017.00122  0.583
2017 Chai R, Li GL, Wang J, Zou J. Hearing Loss: Reestablish the Neural Plasticity in Regenerated Spiral Ganglion Neurons and Sensory Hair Cells. Neural Plasticity. 2017: 1807581. PMID 28316840 DOI: 10.1155/2017/1807581  0.364
2017 Yan W, Liu W, Qi J, Fang Q, Fan Z, Sun G, Han Y, Zhang D, Xu L, Wang M, Li J, Chen F, Liu D, Chai R, Wang H. A Three-Dimensional Culture System with Matrigel Promotes Purified Spiral Ganglion Neuron Survival and Function In Vitro. Molecular Neurobiology. PMID 28283883 DOI: 10.1007/S12035-017-0471-0  0.361
2017 Yu X, Liu W, Fan Z, Qian F, Zhang D, Han Y, Xu L, Sun G, Qi J, Zhang S, Tang M, Li J, Chai R, Wang H. c-Myb knockdown increases the neomycin-induced damage to hair-cell-like HEI-OC1 cells in vitro. Scientific Reports. 7: 41094. PMID 28112219 DOI: 10.1038/Srep41094  0.467
2016 Wang X, Yuan W, Wang X, Qi J, Qin Y, Shi Y, Zhang J, Gong J, Dong Z, Liu X, Sun C, Chai R, Le Noble F, Liu D. The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis. Oncotarget. PMID 27780917 DOI: 10.18632/Oncotarget.12793  0.42
2016 Li Y, Li A, Wu J, He Y, Yu H, Chai R, Li H. MiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a. Cell Death & Disease. 7: e2362. PMID 27607577 DOI: 10.1038/Cddis.2016.246  0.379
2016 Guo R, Zhang S, Xiao M, Qian F, He Z, Li D, Zhang X, Li H, Yang X, Wang M, Chai R, Tang M. Accelerating bioelectric functional development of neural stem cells by graphene coupling: Implications for neural interfacing with conductive materials. Biomaterials. 106: 193-204. PMID 27566868 DOI: 10.1016/J.Biomaterials.2016.08.019  0.338
2016 Ni W, Zeng S, Li W, Chen Y, Zhang S, Tang M, Sun S, Chai R, Li H. Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea. Oncotarget. PMID 27564256 DOI: 10.18632/Oncotarget.11479  0.536
2016 Guan M, Fang Q, He Z, Li Y, Qian F, Qian X, Lu L, Zhang X, Liu D, Qi J, Zhang S, Tang M, Gao X, Chai R. Inhibition of ARC decreases the survival of HEI-OC-1 cells after neomycin damage in vitro. Oncotarget. PMID 27556499 DOI: 10.18632/Oncotarget.11336  0.518
2016 Ni W, Lin C, Guo L, Wu J, Chen Y, Chai R, Li W, Li H. Extensive Supporting Cell Proliferation and Mitotic Hair Cell Generation by In Vivo Genetic Reprogramming in the Neonatal Mouse Cochlea. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8734-45. PMID 27535918 DOI: 10.1523/Jneurosci.0060-16.2016  0.499
2016 Waqas M, Zhang S, He Z, Tang M, Chai R. Role of Wnt and Notch signaling in regulating hair cell regeneration in the cochlea. Frontiers of Medicine. PMID 27527363 DOI: 10.1007/S11684-016-0464-9  0.568
2016 Chen Y, Li W, Li W, Chai R, Li H. Spatiotemporal expression of Ezh2 in the developing mouse cochlear sensory epithelium. Frontiers of Medicine. PMID 27465826 DOI: 10.1007/S11684-016-0459-6  0.494
2016 Wu J, Li W, Lin C, Chen Y, Cheng C, Sun S, Tang M, Chai R, Li H. Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles. Scientific Reports. 6: 29418. PMID 27435629 DOI: 10.1038/Srep29418  0.486
2016 He Z, Sun S, Waqas M, Zhang X, Qian F, Cheng C, Zhang M, Zhang S, Wang Y, Tang M, Li H, Chai R. Reduced TRMU expression increases the sensitivity of hair-cell-like HEI-OC-1 cells to neomycin damage in vitro. Scientific Reports. 6: 29621. PMID 27405449 DOI: 10.1038/Srep29621  0.487
2016 Tang D, Lin Q, He Y, Chai R, Li H. Inhibition of H3K9me2 Reduces Hair Cell Regeneration after Hair Cell Loss in the Zebrafish Lateral Line by Down-Regulating the Wnt and Fgf Signaling Pathways. Frontiers in Molecular Neuroscience. 9: 39. PMID 27303264 DOI: 10.3389/Fnmol.2016.00039  0.502
2016 Li W, You D, Chen Y, Chai R, Li H. Regeneration of hair cells in the mammalian vestibular system. Frontiers of Medicine. PMID 27189205 DOI: 10.1007/S11684-016-0451-1  0.578
2016 Waqas M, Guo L, Zhang S, Chen Y, Zhang X, Wang L, Tang M, Shi H, Bird PI, Li H, Chai R. Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea. Oncotarget. PMID 27070092 DOI: 10.18632/Oncotarget.8636  0.533
2016 Liu L, Chen Y, Qi J, Zhang Y, He Y, Ni W, Li W, Zhang S, Sun S, Taketo MM, Wang L, Chai R, Li H. Wnt activation protects against neomycin-induced hair cell damage in the mouse cochlea. Cell Death & Disease. 7: e2136. PMID 26962686 DOI: 10.1038/Cddis.2016.35  0.368
2016 Lu X, Sun S, Qi J, Li W, Liu L, Zhang Y, Chen Y, Zhang S, Wang L, Miao D, Chai R, Li H. Bmi1 Regulates the Proliferation of Cochlear Supporting Cells Via the Canonical Wnt Signaling Pathway. Molecular Neurobiology. PMID 26843109 DOI: 10.1007/S12035-016-9686-8  0.546
2016 He Y, Tang D, Li W, Chai R, Li H. Histone deacetylase 1 is required for the development of the zebrafish inner ear. Scientific Reports. 6: 16535. PMID 26832938 DOI: 10.1038/Srep16535  0.399
2016 Feng R, Sang Q, Kuang Y, Sun X, Yan Z, Zhang S, Shi J, Tian G, Luchniak A, Fukuda Y, Li B, Yu M, Chen J, Xu Y, Guo L, ... ... Chai R, et al. Mutations in TUBB8 and Human Oocyte Meiotic Arrest. The New England Journal of Medicine. 374: 223-232. PMID 26789871 DOI: 10.1056/Nejmoa1510791  0.332
2016 Chen Y, Liu L, Zhang Y, Chai R, Li H. Wnt activation protects against neomycin-induced hair cell damage in the mouse cochlea The Journal of Laryngology & Otology. 130: S105-S105. DOI: 10.1017/S0022215116003923  0.512
2015 He Y, Wang Z, Sun S, Tang D, Li W, Chai R, Li H. HDAC3 Is Required for Posterior Lateral Line Development in Zebrafish. Molecular Neurobiology. PMID 26395281 DOI: 10.1007/S12035-015-9433-6  0.425
2015 He Y, Tang D, Cai C, Chai R, Li H. LSD1 is Required for Hair Cell Regeneration in Zebrafish. Molecular Neurobiology. PMID 26008620 DOI: 10.1007/S12035-015-9206-2  0.647
2015 Wang X, Wang X, Yuan W, Chai R, Liu D. Egfl6 is involved in zebrafish notochord development. Fish Physiology and Biochemistry. 41: 961-9. PMID 25952972 DOI: 10.1007/S10695-015-0061-X  0.437
2015 Wang T, Chai R, Kim GS, Pham N, Jansson L, Nguyen DH, Kuo B, May LA, Zuo J, Cunningham LL, Cheng AG. Lgr5+ cells regenerate hair cells via proliferation and direct transdifferentiation in damaged neonatal mouse utricle. Nature Communications. 6: 6613. PMID 25849379 DOI: 10.1038/Ncomms7613  0.769
2015 Mei H, Sun S, Bai Y, Chen Y, Chai R, Li H. Reduced mtDNA copy number increases the sensitivity of tumor cells to chemotherapeutic drugs. Cell Death & Disease. 6: e1710. PMID 25837486 DOI: 10.1038/Cddis.2015.78  0.414
2015 Chen Y, Li L, Ni W, Zhang Y, Sun S, Miao D, Chai R, Li H. Bmi1 regulates auditory hair cell survival by maintaining redox balance. Cell Death & Disease. 6: e1605. PMID 25611380 DOI: 10.1038/Cddis.2014.549  0.548
2015 Li W, Wu J, Yang J, Sun S, Chai R, Chen ZY, Li H. Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway. Proceedings of the National Academy of Sciences of the United States of America. 112: 166-71. PMID 25535395 DOI: 10.1073/Pnas.1415901112  0.627
2015 He Y, Yu H, Cai C, Sun S, Chai R, Li H. Inhibition of H3K4me2 Demethylation Protects Auditory Hair Cells from Neomycin-Induced Apoptosis. Molecular Neurobiology. 52: 196-205. PMID 25132091 DOI: 10.1007/S12035-014-8841-3  0.552
2015 Chang DT, Chai R, DiMarco R, Heilshorn SC, Cheng AG. Protein-engineered hydrogel encapsulation for 3-D culture of murine cochlea. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 36: 531-8. PMID 25111520 DOI: 10.1097/Mao.0000000000000518  0.47
2015 Sun S, Yu H, Yu H, Honglin M, Ni W, Zhang Y, Guo L, He Y, Xue Z, Ni Y, Li J, Feng Y, Chen Y, Shao R, Chai R, et al. Inhibition of the activation and recruitment of microglia-like cells protects against neomycin-induced ototoxicity. Molecular Neurobiology. 51: 252-67. PMID 24781382 DOI: 10.1007/S12035-014-8712-Y  0.499
2014 Sun S, Sun M, Zhang Y, Cheng C, Waqas M, Yu H, He Y, Xu B, Wang L, Wang J, Yin S, Chai R, Li H. In vivo overexpression of X-linked inhibitor of apoptosis protein protects against neomycin-induced hair cell loss in the apical turn of the cochlea during the ototoxic-sensitive period. Frontiers in Cellular Neuroscience. 8: 248. PMID 25278835 DOI: 10.3389/Fncel.2014.00248  0.365
2014 Bai X, Lv H, Zhang F, Liu J, Fan Z, Xu L, Han Y, Chai R, Li J, Wang H. Identification of a novel missense mutation in the WFS1 gene as a cause of autosomal dominant nonsyndromic sensorineural hearing loss in all-frequencies. American Journal of Medical Genetics. Part A. 164: 3052-60. PMID 25250959 DOI: 10.1002/Ajmg.A.36760  0.304
2014 Sang Q, Zhang J, Feng R, Wang X, Li Q, Zhao X, Xing Q, Chen W, Du J, Sun S, Chai R, Liu D, Jin L, He L, Li H, et al. Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium and hearing ability in zebrafish: implications for a role in the recessive hearing impairment DFNB42. Human Molecular Genetics. 23: 6201-11. PMID 24990150 DOI: 10.1093/Hmg/Ddu340  0.388
2014 Cox BC, Chai R, Lenoir A, Liu Z, Zhang L, Nguyen DH, Chalasani K, Steigelman KA, Fang J, Rubel EW, Cheng AG, Zuo J. Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo. Development (Cambridge, England). 141: 816-29. PMID 24496619 DOI: 10.1242/Dev.103036  0.787
2013 Volkenstein S, Oshima K, Sinkkonen ST, Corrales CE, Most SP, Chai R, Jan TA, van Amerongen R, Cheng AG, Heller S. Transient, afferent input-dependent, postnatal niche for neural progenitor cells in the cochlear nucleus. Proceedings of the National Academy of Sciences of the United States of America. 110: 14456-61. PMID 23940359 DOI: 10.1073/Pnas.1307376110  0.782
2013 Jan TA, Chai R, Sayyid ZN, van Amerongen R, Xia A, Wang T, Sinkkonen ST, Zeng YA, Levin JR, Heller S, Nusse R, Cheng AG. Tympanic border cells are Wnt-responsive and can act as progenitors for postnatal mouse cochlear cells. Development (Cambridge, England). 140: 1196-206. PMID 23444352 DOI: 10.1242/Dev.087528  0.806
2013 Vu AA, Nadaraja GS, Huth ME, Luk L, Kim J, Chai R, Ricci AJ, Cheng AG. Integrity and regeneration of mechanotransduction machinery regulate aminoglycoside entry and sensory cell death. Plos One. 8: e54794. PMID 23359017 DOI: 10.1371/Journal.Pone.0054794  0.676
2012 Chai R, Kuo B, Wang T, Liaw EJ, Xia A, Jan TA, Liu Z, Taketo MM, Oghalai JS, Nusse R, Zuo J, Cheng AG. Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea. Proceedings of the National Academy of Sciences of the United States of America. 109: 8167-72. PMID 22562792 DOI: 10.1073/Pnas.1202774109  0.83
2011 Sinkkonen ST, Chai R, Jan TA, Hartman BH, Laske RD, Gahlen F, Sinkkonen W, Cheng AG, Oshima K, Heller S. Intrinsic regenerative potential of murine cochlear supporting cells. Scientific Reports. 1: 26. PMID 22355545 DOI: 10.1038/Srep00026  0.822
2011 Jan TA, Chai R, Sayyid ZN, Cheng AG. Isolating LacZ-expressing cells from mouse inner ear tissues using flow cytometry. Journal of Visualized Experiments : Jove. e3432. PMID 22217925 DOI: 10.3791/3432  0.798
2011 Chai R, Xia A, Wang T, Jan TA, Hayashi T, Bermingham-McDonogh O, Cheng AG. Dynamic expression of Lgr5, a Wnt target gene, in the developing and mature mouse cochlea. Journal of the Association For Research in Otolaryngology : Jaro. 12: 455-69. PMID 21472479 DOI: 10.1007/S10162-011-0267-2  0.799
2009 Chai R, Chen S, Ding J, Grayburn PA. Efficient, glucose responsive and islet-specific transgene expression by a modified rat insulin promoter. Gene Therapy. 16: 1202-9. PMID 19727136 DOI: 10.1038/Gt.2009.114  0.775
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