Gordon F. Tomaselli - Publications

Affiliations: 
Medicine Johns Hopkins Medical School/HHMI, Baltimore, MD, United States 

97 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Tomaselli GF. BIOLOGICAL ANTIARRHYTHMICS-SODIUM CHANNEL INTERACTING PROTEINS. Transactions of the American Clinical and Climatological Association. 133: 136-148. PMID 37701589  0.325
2022 Chakouri N, Rivas S, Roybal D, Yang L, Diaz J, Hsu A, Mahling R, Chen BX, Owoyemi JO, DiSilvestre D, Sirabella D, Corneo B, Tomaselli GF, Dick IE, Marx SO, et al. Fibroblast growth factor homologous factors serve as a molecular rheostat in tuning arrhythmogenic cardiac late sodium current. Nature Cardiovascular Research. 1: 1-13. PMID 35662881 DOI: 10.1038/s44161-022-00060-6  0.331
2022 Srinivasan L, Alzogaray V, Selvakumar D, Nathan S, Yoder JB, Wright KM, Klinke S, Nwafor JN, Labanda MS, Goldbaum FA, Schön A, Freire E, Tomaselli GF, Amzel LM, Ben-Johny M, et al. Development of High affinity Nanobodies Specific for Na1.4 and Na1.5 Voltage-Gated Sodium Channel Isoforms. The Journal of Biological Chemistry. 101763. PMID 35202650 DOI: 10.1016/j.jbc.2022.101763  0.6
2021 Kang PW, Chakouri N, Diaz J, Tomaselli GF, Yue DT, Ben-Johny M. Elementary mechanisms of calmodulin regulation of Na1.5 producing divergent arrhythmogenic phenotypes. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34021086 DOI: 10.1073/pnas.2025085118  0.318
2021 Nathan S, Gabelli SB, Yoder JB, Srinivasan L, Aldrich RW, Tomaselli GF, Ben-Johny M, Amzel LM. Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation. The Journal of General Physiology. 153. PMID 33306788 DOI: 10.1085/jgp.202012722  0.616
2020 McNally EM, Mann DL, Pinto Y, Bhakta D, Tomaselli G, Nazarian S, Groh WJ, Tamura T, Duboc D, Itoh H, Hellerstein L, Mammen PPA. Clinical Care Recommendations for Cardiologists Treating Adults With Myotonic Dystrophy. Journal of the American Heart Association. 9: e014006. PMID 32067592 DOI: 10.1161/Jaha.119.014006  0.302
2020 Chakouri N, wei Kang P, Diaz J, Tomaselli GF, Johny MB. Aberrant Calmodulin Regulation of NaV1.5 Channels Linked to Inherited Cardiac Arrhythmia Biophysical Journal. 118: 577a. DOI: 10.1016/j.bpj.2019.11.3133  0.348
2019 Yoder JB, Ben-Johny M, Farinelli F, Srinivasan L, Shoemaker SR, Tomaselli GF, Gabelli SB, Amzel LM. Ca-dependent regulation of sodium channels Na1.4 and Na1.5 is controlled by the post-IQ motif. Nature Communications. 10: 1514. PMID 30944319 DOI: 10.1038/S41467-019-09570-7  0.628
2019 Nathan S, Shoemaker S, Farinelli F, Yoder J, Amzel LM, Tomaselli GF, Gabelli SB. An Attempted Molecular Rescue of an Arrhythmogenic Cardiac Disease Mutation Biophysical Journal. 116: 387a. DOI: 10.1016/J.Bpj.2018.11.2097  0.559
2018 Blazeski A, Lowenthal J, Wang Y, Teuben R, Zhu R, Gerecht S, Tomaselli G, Tung L. Engineered Heart Slice Model of Arrhythmogenic Cardiomyopathy using Plakophilin-2 Mutant Myocytes. Tissue Engineering. Part A. PMID 30520705 DOI: 10.1089/Ten.Tea.2018.0272  0.33
2018 Banerjee R, Yoder JB, Yue DT, Amzel LM, Tomaselli GF, Gabelli SB, Ben-Johny M. Bilobal architecture is a requirement for calmodulin signaling to Ca1.3 channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 29531055 DOI: 10.1073/Pnas.1716381115  0.605
2017 Limipitikul W, Ong CS, Tomaselli GF. Neuromuscular Disease: Cardiac Manifestations and Sudden Death Risk. Cardiac Electrophysiology Clinics. 9: 731-747. PMID 29173414 DOI: 10.1016/J.Ccep.2017.07.013  0.372
2017 Jeong MH, Kim HJ, Pyun JH, Choi KS, Lee DI, Solhjoo S, O'Rourke B, Tomaselli GF, Jeong DS, Cho H, Kang JS. Cdon deficiency causes cardiac remodeling through hyperactivation of WNT/β-catenin signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 28154134 DOI: 10.1073/Pnas.1615105114  0.36
2016 Zhang Y, Guallar E, Blasco-Colmenares E, Harms AC, Vreeken RJ, Hankemeier T, Tomaselli GF, Cheng A. Serum-Based Oxylipins Are Associated with Outcomes in Primary Prevention Implantable Cardioverter Defibrillator Patients. Plos One. 11: e0157035. PMID 27281224 DOI: 10.1371/Journal.Pone.0157035  0.307
2016 DeMazumder D, Limpitikul WB, Dorante M, Dey S, Mukhopadhyay B, Zhang Y, Moorman JR, Cheng A, Berger RD, Guallar E, Jones SR, Tomaselli GF. Entropy of cardiac repolarization predicts ventricular arrhythmias and mortality in patients receiving an implantable cardioverter-defibrillator for primary prevention of sudden death. Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups On Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology. PMID 27044982 DOI: 10.1093/Europace/Euv399  0.362
2016 Johny MB, Tomaselli GF, Yue DT. Dynamic Interplay of Calmodulin and Fibroblast Growth Factor Homologous Factors in Regulating NA Channels Biophysical Journal. 110: 605a-606a. DOI: 10.1016/j.bpj.2015.11.3234  0.322
2016 Limpitikul WB, Limphong P, Dick IE, Hyun Choi M, Yang W, Babich J, Tester DJ, Ackerman MJ, Tomaselli GF, Yue DT. Functional Rescue of Calmodulinopathy IPSC-Derived Cardiomyocytes -- a Foray into Personalized Medicine Biophysical Journal. 110: 439a. DOI: 10.1016/J.Bpj.2015.11.2367  0.374
2015 Li H, Lichter JG, Seidel T, Tomaselli GF, Bridge JH, Sachse FB. Cardiac Resynchronization Therapy Reduces Subcellular Heterogeneity of Ryanodine Receptors, T-Tubules and Ca2+ Sparks Produced by Dyssynchronous Heart Failure. Circulation. Heart Failure. PMID 26294422 DOI: 10.1161/Circheartfailure.115.002352  0.376
2015 Zhang Y, Guallar E, Blasco-Colmenares E, Butcher B, Norgard S, Nauffal V, Marine JE, Eldadah Z, Dickfeld T, Ellenbogen KA, Tomaselli GF, Cheng A. Changes in Follow-Up Left Ventricular Ejection Fraction Associated With Outcomes in Primary Prevention Implantable Cardioverter-Defibrillator and Cardiac Resynchronization Therapy Device Recipients. Journal of the American College of Cardiology. 66: 524-31. PMID 26227190 DOI: 10.1016/J.Jacc.2015.05.057  0.362
2015 Gabelli SB, Yoder JB, Tomaselli GF, Amzel LM. Calmodulin and Ca(2+) control of voltage gated Na(+) channels. Channels (Austin, Tex.). 0. PMID 26218606 DOI: 10.1080/19336950.2015.1075677  0.653
2015 Dick IE, Limpitikul WB, Niu J, Banerjee R, Issa JB, Ben-Johny M, Adams PJ, Kang PW, Lee SR, Sang L, Yang W, Babich J, Zhang M, Bazazzi H, Yue NC, ... Tomaselli GF, et al. A rendezvous with the queen of ion channels: Three decades of ion channel research by David T. Yue and his Calcium Signals Laboratory. Channels (Austin, Tex.). 0. PMID 26176690 DOI: 10.1080/19336950.2015.1051272  0.338
2015 Yousuf O, Chrispin J, Tomaselli GF, Berger RD. Clinical management and prevention of sudden cardiac death. Circulation Research. 116: 2020-40. PMID 26044254 DOI: 10.1161/Circresaha.116.304555  0.347
2015 DeMazumder D, Kass DA, O'Rourke B, Tomaselli GF. Cardiac resynchronization therapy restores sympathovagal balance in the failing heart by differential remodeling of cholinergic signaling. Circulation Research. 116: 1691-9. PMID 25733594 DOI: 10.1161/Circresaha.116.305268  0.35
2015 Gabelli SB, Boto A, Halpernin V, Bianchet MA, Farinelli F, Aripirala S, Yoder JB, Jakoncic J, Tomaselli GF, Amzel M. Cardiac Sodium Channel: Activation by CaM Involves a NaV1.5-NaV1.5 Interaction Biophysical Journal. 108: 127a-128a. DOI: 10.1016/J.Bpj.2014.11.712  0.66
2015 Farinelli F, DiSilvestre D, Dong P, Tian Y, Tomaselli G. CaMKII-Dependent Regulation of Cardiac Sodium Channel Biophysical Journal. 108: 576a-577a. DOI: 10.1016/j.bpj.2014.11.3151  0.342
2014 Gabelli SB, Boto A, Kuhns VH, Bianchet MA, Farinelli F, Aripirala S, Yoder J, Jakoncic J, Tomaselli GF, Amzel LM. Regulation of the NaV1.5 cytoplasmic domain by calmodulin. Nature Communications. 5: 5126. PMID 25370050 DOI: 10.1038/Ncomms6126  0.617
2014 Lichter JG, Carruth E, Mitchell C, Barth AS, Aiba T, Kass DA, Tomaselli GF, Bridge JH, Sachse FB. Remodeling of the sarcomeric cytoskeleton in cardiac ventricular myocytes during heart failure and after cardiac resynchronization therapy. Journal of Molecular and Cellular Cardiology. 72: 186-95. PMID 24657727 DOI: 10.1016/J.Yjmcc.2014.03.012  0.334
2013 DeMazumder D, Lake DE, Cheng A, Moss TJ, Guallar E, Weiss RG, Jones SR, Tomaselli GF, Moorman JR. Dynamic analysis of cardiac rhythms for discriminating atrial fibrillation from lethal ventricular arrhythmias. Circulation. Arrhythmia and Electrophysiology. 6: 555-61. PMID 23685539 DOI: 10.1161/Circep.113.000034  0.355
2013 Aiba T, Barth AS, Hesketh GG, Hashambhoy YL, Chakir K, Tunin RS, Greenstein JL, Winslow RL, Kass DA, Tomaselli GF. Cardiac resynchronization therapy improves altered Na channel gating in canine model of dyssynchronous heart failure. Circulation. Arrhythmia and Electrophysiology. 6: 546-54. PMID 23650309 DOI: 10.1161/Circep.113.000400  0.454
2013 Tereshchenko L, Arking D, Sotoodehnia N, Zhang Y, Han L, Berger R, Tomaselli G, Siscovick D, Post W, Coresh J, Guallar E, Soliman E. ELECTRICAL REMODELING PREDICTS RISK OF SUDDEN CARDIAC DEATH IN ASYMPTOMATIC ADULTS Journal of the American College of Cardiology. 61: E1340. DOI: 10.1016/S0735-1097(13)61340-6  0.332
2012 Das S, Aiba T, Rosenberg M, Hessler K, Xiao C, Quintero PA, Ottaviano FG, Knight AC, Graham EL, Boström P, Morissette MR, del Monte F, Begley MJ, Cantley LC, Ellinor PT, ... Tomaselli GF, et al. Pathological role of serum- and glucocorticoid-regulated kinase 1 in adverse ventricular remodeling. Circulation. 126: 2208-19. PMID 23019294 DOI: 10.1161/Circulationaha.112.115592  0.322
2012 Zhang H, Zou B, Yu H, Moretti A, Wang X, Yan W, Babcock JJ, Bellin M, McManus OB, Tomaselli G, Nan F, Laugwitz KL, Li M. Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 109: 11866-71. PMID 22745159 DOI: 10.1073/Pnas.1205266109  0.304
2012 Aiba T, Tomaselli G. Electrical remodeling in dyssynchrony and resynchronization. Journal of Cardiovascular Translational Research. 5: 170-9. PMID 22271011 DOI: 10.1007/S12265-012-9348-9  0.455
2012 DeMazumder D, Tomaselli GF. Molecular and cellular mechanisms of cardiac arrhythmias Muscle. 1: 583-599. DOI: 10.1016/B978-0-12-381510-1.00041-7  0.363
2011 Liang HY, Cheng A, Chang KC, Berger RD, Agarwal K, Eulitt P, Corretti M, Tomaselli G, Calkins H, Kass DA, Abraham TP. Influence of atrial function and mechanical synchrony on LV hemodynamic status in heart failure patients on resynchronization therapy. Jacc. Cardiovascular Imaging. 4: 691-8. PMID 21757157 DOI: 10.1016/J.Jcmg.2011.02.019  0.356
2011 Tomaselli GF. Cell-based therapy of cardiac arrhythmias: designer cables and Zeno's paradox. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 8: 131-2. PMID 21056122 DOI: 10.1016/J.Hrthm.2010.11.001  0.309
2010 Aiba T, Hesketh GG, Liu T, Carlisle R, Villa-Abrille MC, O'Rourke B, Akar FG, Tomaselli GF. Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes. Cardiovascular Research. 85: 454-63. PMID 19797425 DOI: 10.1093/Cvr/Cvp324  0.402
2010 Aiba T, Tomaselli GF, Shimizu W. Electrophysiological Remodeling in Heart Failure Dyssynchrony vs. Resynchronization Journal of Arrhythmia. 26: 79-90. DOI: 10.1016/S1880-4276(10)80011-0  0.453
2009 Tomaselli GF. Oxidant stress derails the cardiac connexon connection. The Journal of Clinical Investigation. 120: 87-9. PMID 20038808 DOI: 10.1172/Jci41780  0.329
2009 Chugh SS, Donahue JK, Kaufman ES, Link MS, Markowitz SM, Narayan SM, Quan KJ, Tomaselli GF, Verdino R. The future of fellowship training in clinical cardiac electrophysiology: Program directors' perspective 2008. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 6: 1606-12. PMID 19879538 DOI: 10.1016/J.Hrthm.2009.07.044  0.31
2009 Barth AS, Tomaselli GF. Cardiac metabolism and arrhythmias. Circulation. Arrhythmia and Electrophysiology. 2: 327-35. PMID 19808483 DOI: 10.1161/Circep.108.817320  0.434
2009 Cheng A, Dalal D, Fetics BJ, Angkeow P, Spragg DD, Calkins H, Tomaselli GF, Berger RD. Ibutilide-induced changes in the temporal lability of ventricular repolarization in patients with and without structural heart disease. Journal of Cardiovascular Electrophysiology. 20: 873-9. PMID 19460072 DOI: 10.1111/J.1540-8167.2009.01476.X  0.367
2009 Biswas S, DiSilvestre D, Tian Y, Halperin VL, Tomaselli GF. Calcium-mediated dual-mode regulation of cardiac sodium channel gating. Circulation Research. 104: 870-8. PMID 19265034 DOI: 10.1161/CIRCRESAHA.108.193565  0.313
2009 Nazarian S, Dong J, Tomaselli GF, Marine JE. Profound hypotension due to slow atrioventricular nodal pathway conduction during atrial tachycardia. Pacing and Clinical Electrophysiology : Pace. 32: 278-80. PMID 19170923 DOI: 10.1111/J.1540-8159.2008.02216.X  0.355
2008 Bilchick KC, Dimaano V, Wu KC, Helm RH, Weiss RG, Lima JA, Berger RD, Tomaselli GF, Bluemke DA, Halperin HR, Abraham T, Kass DA, Lardo AC. Cardiac magnetic resonance assessment of dyssynchrony and myocardial scar predicts function class improvement following cardiac resynchronization therapy. Jacc. Cardiovascular Imaging. 1: 561-8. PMID 19356481 DOI: 10.1016/J.Jcmg.2008.04.013  0.306
2008 Kostis WJ, Tedford RJ, Miller DL, Schulman SP, Tomaselli GF. Troponin-I elevation in a young man with arrhythmogenic right ventricular dysplasia/cardiomyopathy. Journal of Interventional Cardiac Electrophysiology : An International Journal of Arrhythmias and Pacing. 22: 49-53. PMID 18392928 DOI: 10.1007/S10840-008-9250-1  0.337
2008 Nass RD, Aiba T, Tomaselli GF, Akar FG. Mechanisms of disease: ion channel remodeling in the failing ventricle. Nature Clinical Practice. Cardiovascular Medicine. 5: 196-207. PMID 18317475 DOI: 10.1038/ncpcardio1130  0.325
2007 Marine JE, Tomaselli GF, Leng CT. Inappropriate implantable cardioverter-defibrillator discharge associated with a new ventricular tachycardia treatment algorithm. Heart Rhythm. 4: 655-7. PMID 17467637 DOI: 10.1016/J.Hrthm.2006.12.049  0.311
2006 Xiong W, Farukhi YZ, Tian Y, Disilvestre D, Li RA, Tomaselli GF. A conserved ring of charge in mammalian Na+ channels: a molecular regulator of the outer pore conformation during slow inactivation. The Journal of Physiology. 576: 739-54. PMID 16873407 DOI: 10.1113/Jphysiol.2006.115105  0.388
2006 Gao Z, Xu H, DiSilvestre D, Halperin VL, Tunin R, Tian Y, Yu W, Winslow RL, Tomaselli GF. Transcriptomic profiling of the canine tachycardia-induced heart failure model: global comparison to human and murine heart failure. Journal of Molecular and Cellular Cardiology. 40: 76-86. PMID 16236311 DOI: 10.1016/J.Yjmcc.2005.08.002  0.346
2006 Shah M, Akar FG, Tomaselli GF. Molecular basis of arrhythmias. Circulation. 112: 2517-29. PMID 16230503 DOI: 10.1161/CIRCULATIONAHA.104.494476  0.306
2006 Akar FG, Tomaselli GF. Conduction abnormalities in nonischemic dilated cardiomyopathy: basic mechanisms and arrhythmic consequences. Trends in Cardiovascular Medicine. 15: 259-64. PMID 16226681 DOI: 10.1016/J.Tcm.2005.08.002  0.38
2005 Azene EM, Xue T, Marbán E, Tomaselli GF, Li RA. Non-equilibrium behavior of HCN channels: insights into the role of HCN channels in native and engineered pacemakers. Cardiovascular Research. 67: 263-73. PMID 16005302 DOI: 10.1016/J.Cardiores.2005.03.006  0.334
2005 Akar FG, Tomaselli GF. Ion channels as novel therapeutic targets in heart failure. Annals of Medicine. 37: 44-54. PMID 15902846 DOI: 10.1080/07853890510007214  0.415
2005 Tomaselli GF. Ventricularization of atrial gene expression in the fibrillating heart? Circulation Research. 96: 923-4. PMID 15890977 DOI: 10.1161/01.Res.0000168041.46134.8E  0.357
2005 Tomaselli GF, Zipes DP. What causes sudden death in heart failure? Circulation Research. 95: 754-63. PMID 15486322 DOI: 10.1161/01.Res.0000145047.14691.Db  0.382
2004 Akar FG, Spragg DD, Tunin RS, Kass DA, Tomaselli GF. Mechanisms underlying conduction slowing and arrhythmogenesis in nonischemic dilated cardiomyopathy. Circulation Research. 95: 717-25. PMID 15345654 DOI: 10.1161/01.Res.0000144125.61927.1C  0.383
2004 Li RA, Tomaselli GF. Using the deadly mu-conotoxins as probes of voltage-gated sodium channels. Toxicon : Official Journal of the International Society On Toxinology. 44: 117-22. PMID 15246758 DOI: 10.1016/J.Toxicon.2004.03.028  0.402
2003 Xiong W, Li RA, Tian Y, Tomaselli GF. Molecular motions of the outer ring of charge of the sodium channel: do they couple to slow inactivation? The Journal of General Physiology. 122: 323-32. PMID 12913092 DOI: 10.1085/Jgp.200308881  0.358
2003 Armoundas AA, Hobai IA, Tomaselli GF, Winslow RL, O'Rourke B. Role of sodium-calcium exchanger in modulating the action potential of ventricular myocytes from normal and failing hearts. Circulation Research. 93: 46-53. PMID 12805237 DOI: 10.1161/01.Res.0000080932.98903.D8  0.357
2003 Kondratiev A, Hahin R, Tomaselli GF. Isoform-specific effects of a novel BmK 11(2) peptide toxin on Na channels. Toxicon : Official Journal of the International Society On Toxinology. 41: 269-76. PMID 12565748 DOI: 10.1016/S0041-0101(02)00286-6  0.306
2003 Li RA, Ennis IL, Xue T, Nguyen HM, Tomaselli GF, Goldin AL, Marbán E. Molecular basis of isoform-specific micro-conotoxin block of cardiac, skeletal muscle, and brain Na+ channels. The Journal of Biological Chemistry. 278: 8717-24. PMID 12471026 DOI: 10.1074/Jbc.M210882200  0.357
2002 Deschênes I, DiSilvestre D, Juang GJ, Wu RC, An WF, Tomaselli GF. Regulation of Kv4.3 current by KChIP2 splice variants: a component of native cardiac I(to)? Circulation. 106: 423-9. PMID 12135940 DOI: 10.1161/01.Cir.0000025417.65658.B6  0.31
2002 Chen Z, Alcayaga C, Suarez-Isla BA, O'Rourke B, Tomaselli G, Marban E. A "minimal" sodium channel construct consisting of ligated S5-P-S6 segments forms a toxin-activatable ionophore. The Journal of Biological Chemistry. 277: 24653-8. PMID 11973330 DOI: 10.1074/jbc.M111862200  0.306
2002 Deschênes I, Neyroud N, DiSilvestre D, Marbán E, Yue DT, Tomaselli GF. Isoform-specific modulation of voltage-gated Na(+) channels by calmodulin. Circulation Research. 90: E49-57. PMID 11884381 DOI: 10.1161/01.Res.0000012502.92751.E6  0.347
2002 Li RA, Sato K, Kodama K, Kohno T, Xue T, Tomaselli GF, Marbán E. Charge conversion enables quantification of the proximity between a normally-neutral mu-conotoxin (GIIIA) site and the Na+ channel pore. Febs Letters. 511: 159-64. PMID 11821068 DOI: 10.1016/S0014-5793(01)03316-6  0.369
2002 Li RA, Ennis IL, Tomaselli GF, Marbán E. Structural basis of differences in isoform-specific gating and lidocaine block between cardiac and skeletal muscle sodium channels. Molecular Pharmacology. 61: 136-41. PMID 11752214 DOI: 10.1124/Mol.61.1.136  0.458
2001 Vélez P, Sierralta J, Alcayaga C, Fonseca M, Loyola H, Johns DC, Tomaselli GF, Marbán E, Suárez-Isla BA. A functional assay for paralytic shellfish toxins that uses recombinant sodium channels. Toxicon : Official Journal of the International Society On Toxinology. 39: 929-35. PMID 11223080 DOI: 10.1016/S0041-0101(00)00230-0  0.349
2001 Li RA, Ennis IL, French RJ, Dudley SC, Tomaselli GF, Marbán E. Clockwise domain arrangement of the sodium channel revealed by (mu)-conotoxin (GIIIA) docking orientation. The Journal of Biological Chemistry. 276: 11072-7. PMID 11154701 DOI: 10.1074/Jbc.M010862200  0.403
2001 Winslow RL, Greenstein JL, Tomaselli GF, O'Rourke B. Computational models of the failing myocyte: Relating altered gene expression to cellular function Philosophical Transactions of the Royal Society a: Mathematical, Physical and Engineering Sciences. 359: 1187-1200. DOI: 10.1098/Rsta.2001.0825  0.341
2000 Numaguchi H, Mullins FM, Johnson JP, Johns DC, Po SS, Yang IC, Tomaselli GF, Balser JR. Probing the interaction between inactivation gating and Dd-sotalol block of HERG. Circulation Research. 87: 1012-8. PMID 11090546 DOI: 10.1161/01.Res.87.11.1012  0.374
2000 Ong BH, Tomaselli GF, Balser JR. A structural rearrangement in the sodium channel pore linked to slow inactivation and use dependence Journal of General Physiology. 116: 653-661. PMID 11055994 DOI: 10.1085/Jgp.116.5.653  0.389
2000 Taylor E, Berger R, Hummel JD, Dinerman JL, Kenknight B, Arria AM, Tomaselli G, Calkins H. Analysis of the pattern of initiation of sustained ventricular arrhythmias in patients with implantable defibrillators. Journal of Cardiovascular Electrophysiology. 11: 719-726. PMID 10921786 DOI: 10.1111/J.1540-8167.2000.Tb00040.X  0.369
2000 Li RA, Ennis IL, Vélez P, Tomaselli GF, Marbán E. Novel structural determinants of mu-conotoxin (GIIIB) block in rat skeletal muscle (mu1) Na+ channels. The Journal of Biological Chemistry. 275: 27551-8. PMID 10859326 DOI: 10.1074/Jbc.M909719199  0.302
2000 Kambouris NG, Nuss HB, Johns DC, Marbán E, Tomaselli GF, Balser JR. A revised view of cardiac sodium channel "blockade" in the long-QT syndrome. The Journal of Clinical Investigation. 105: 1133-40. PMID 10772658 DOI: 10.1172/Jci9212  0.357
2000 Chen Z, Ong BH, Kambouris NG, Marbán E, Tomaselli GF, Balser JR. Lidocaine induces a slow inactivated state in rat skeletal muscle sodium channels. The Journal of Physiology. 524: 37-49. PMID 10747182 DOI: 10.1111/J.1469-7793.2000.T01-1-00037.X  0.408
2000 Nuss HB, Kambouris NG, Marbán E, Tomaselli GF, Balser JR. Isoform-specific lidocaine block of sodium channels explained by differences in gating. Biophysical Journal. 78: 200-10. PMID 10620286 DOI: 10.1016/S0006-3495(00)76585-4  0.402
2000 Li RA, Vélez P, Chiamvimonvat N, Tomaselli GF, Marbán E. Charged residues between the selectivity filter and S6 segments contribute to the permeation phenotype of the sodium channel. The Journal of General Physiology. 115: 81-92. PMID 10613920 DOI: 10.1085/Jgp.115.1.81  0.314
1999 Nuss HB, Kääb S, Kass DA, Tomaselli GF, Marbán E. Cellular basis of ventricular arrhythmias and abnormal automaticity in heart failure. The American Journal of Physiology. 277: H80-91. PMID 10409185 DOI: 10.1152/Ajpheart.1999.277.1.H80  0.37
1998 Kambouris NG, Hastings LA, Stepanovic S, Marban E, Tomaselli GF, Balser JR. Mechanistic link between lidocaine block and inactivation probed by outer pore mutations in the rat micro1 skeletal muscle sodium channel. The Journal of Physiology. 512: 693-705. PMID 9769414 DOI: 10.1111/J.1469-7793.1998.693Bd.X  0.389
1998 Kääb S, Dixon J, Duc J, Ashen D, Näbauer M, Beuckelmann DJ, Steinbeck G, McKinnon D, Tomaselli GF. Molecular basis of transient outward potassium current downregulation in human heart failure: a decrease in Kv4.3 mRNA correlates with a reduction in current density. Circulation. 98: 1383-93. PMID 9760292 DOI: 10.1161/01.Cir.98.14.1383  0.414
1998 Ranjan R, Chiamvimonvat N, Thakor NV, Tomaselli GF, Marban E. Mechanism of anode break stimulation in the heart. Biophysical Journal. 74: 1850-63. PMID 9545047 DOI: 10.1016/S0006-3495(98)77895-6  0.345
1998 Marban E, Yamagishi T, Tomaselli GF. Structure and function of voltage-gated sodium channels. The Journal of Physiology. 508: 647-57. PMID 9518722 DOI: 10.1111/J.1469-7793.1998.647BP.X  0.309
1998 Kambouris NG, Nuss HB, Johns DC, Tomaselli GF, Marban E, Balser JR. Phenotypic characterization of a novel long-QT syndrome mutation (R1623Q) in the cardiac sodium channel. Circulation. 97: 640-4. PMID 9495298 DOI: 10.1161/01.Cir.97.7.640  0.4
1997 Yamagishi T, Janecki M, Marban E, Tomaselli GF. Topology of the P segments in the sodium channel pore revealed by cysteine mutagenesis. Biophysical Journal. 73: 195-204. PMID 9199784 DOI: 10.1016/S0006-3495(97)78060-3  0.391
1997 Pérez-García MT, Chiamvimonvat N, Ranjan R, Balser JR, Tomaselli GF, Marban E. Mechanisms of sodium/calcium selectivity in sodium channels probed by cysteine mutagenesis and sulfhydryl modification. Biophysical Journal. 72: 989-96. PMID 9138597 DOI: 10.1016/S0006-3495(97)78751-4  0.399
1996 Chiamvimonvat N, Pérez-García MT, Tomaselli GF, Marban E. Control of ion flux and selectivity by negatively charged residues in the outer mouth of rat sodium channels. The Journal of Physiology. 491: 51-9. PMID 9011621 DOI: 10.1113/Jphysiol.1996.Sp021195  0.359
1996 Balser JR, Nuss HB, Orias DW, Johns DC, Marban E, Tomaselli GF, Lawrence JH. Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels. The Journal of Clinical Investigation. 98: 2874-86. PMID 8981936 DOI: 10.1172/Jci119116  0.414
1996 Lawrence JH, Orias DW, Balser JR, Nuss HB, Tomaselli GF, O'Rourke B, Marban E. Single-channel analysis of inactivation-defective rat skeletal muscle sodium channels containing the F1304Q mutation. Biophysical Journal. 71: 1285-94. PMID 8874003 DOI: 10.1016/S0006-3495(96)79329-3  0.402
1996 Nuss HB, Balser JR, Orias DW, Lawrence JH, Tomaselli GF, Marban E. Coupling between fast and slow inactivation revealed by analysis of a point mutation (F1304Q) in mu 1 rat skeletal muscle sodium channels. The Journal of Physiology. 494: 411-29. PMID 8842001  0.303
1996 Kääb S, Nuss HB, Chiamvimonvat N, O'Rourke B, Pak PH, Kass DA, Marban E, Tomaselli GF. Ionic mechanism of action potential prolongation in ventricular myocytes from dogs with pacing-induced heart failure. Circulation Research. 78: 262-73. PMID 8575070 DOI: 10.1161/01.Res.78.2.262  0.41
1995 Tomaselli GF, Chiamvimonvat N, Nuss HB, Balser JR, Perez-Garcia MT, Ruo Hui Xu, Orias DW, Backx PH, Marban E. A mutation in the pore of the sodium channel alters gating Biophysical Journal. 68: 1814-1827. PMID 7612823 DOI: 10.1016/S0006-3495(95)80358-9  0.309
1994 Kienker P, Tomaselli G, Jurman M, Yellen G. Conductance mutations of the nicotinic acetylcholine receptor do not act by a simple electrostatic mechanism. Biophysical Journal. 66: 325-34. PMID 8161686 DOI: 10.1016/S0006-3495(94)80781-7  0.316
1994 Mejía-Alvarez R, Tomaselli GF, Marban E. Simultaneous expression of cardiac and skeletal muscle isoforms of the L-type Ca2+ channel in a rat heart muscle cell line. The Journal of Physiology. 478: 315-29. PMID 7525945 DOI: 10.1113/Jphysiol.1994.Sp020252  0.418
1993 Tomaselli GF, Backx PH, Marban E. Molecular basis of permeation in voltage-gated ion channels. Circulation Research. 72: 491-6. PMID 7679332 DOI: 10.1161/01.Res.72.3.491  0.36
1992 Backx PH, Yue DT, Lawrence JH, Marban E, Tomaselli GF. Molecular localization of an ion-binding site within the pore of mammalian sodium channels. Science (New York, N.Y.). 257: 248-51. PMID 1321496 DOI: 10.1126/Science.1321496  0.317
1990 Tomaselli GF, Feldman AM, Yellen G, Marban E. Human cardiac sodium channels expressed in Xenopus oocytes. The American Journal of Physiology. 258: H903-6. PMID 1690519 DOI: 10.1152/ajpheart.1990.258.3.H903  0.305
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