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Thomas Ried - Publications

Affiliations: 
Cancer Genomics National Cancer Institute, Rockville, MD, United States 
Area:
genomic instability and associated gene expression changes during cancer development
Website:
http://ccr.cancer.gov/staff/staff.asp?profileid=5680

297 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Pongor LS, Schultz CW, Rinaldi L, Wangsa D, Redon CE, Takahashi N, Fialkoff G, Desai P, Zhang Y, Burkett S, Hermoni N, Vilk N, Gutin J, Rona G, Zhao Y, ... ... Ried T, et al. Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and is Associated with Worse Outcomes. Cancer Discovery. PMID 36715552 DOI: 10.1158/2159-8290.CD-22-0796  0.308
2021 Bronder D, Tighe A, Wangsa D, Zong D, Meyer TJ, Wardenaar R, Minshall P, Hirsch D, Heselmeyer-Haddad K, Nelson L, Spierings D, McGrail JC, Cam M, Nussenzweig A, Foijer F, ... Ried T, et al. TP53 loss initiates chromosomal instability in fallopian tube epithelial cells. Disease Models & Mechanisms. PMID 34569598 DOI: 10.1242/dmm.049001  0.323
2021 Trakala M, Aggarwal M, Sniffen C, Zasadil L, Carroll A, Ma D, Su XA, Wangsa D, Meyer A, Sieben CJ, Zhong J, Hsu PH, Paradis G, Ried T, Holland A, et al. Clonal selection of stable aneuploidies in progenitor cells drives high-prevalence tumorigenesis. Genes & Development. PMID 34266888 DOI: 10.1101/gad.348341.121  0.398
2021 Patkar S, Heselmeyer-Haddad K, Auslander N, Hirsch D, Camps J, Bronder D, Brown M, Chen WD, Lokanga R, Wangsa D, Wangsa D, Hu Y, Lischka A, Braun R, Emons G, ... ... Ried T, et al. Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies. Genome Medicine. 13: 93. PMID 34034815 DOI: 10.1186/s13073-021-00905-y  0.781
2021 Shrestha RL, Rossi A, Wangsa D, Hogan AK, Zaldana KS, Suva E, Chung YJ, Sanders CL, Difilippantonio S, Karpova TS, Karim B, Foltz DR, Fachinetti D, Aplan PD, Ried T, et al. CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity. The Journal of Cell Biology. 220. PMID 33620383 DOI: 10.1083/jcb.202007195  0.424
2020 Hirsch D, Hardt J, Sauer C, Heselmeyer-Hadded K, Witt SH, Kienle P, Ried T, Gaiser T. Molecular characterization of ulcerative colitis-associated colorectal carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 33318582 DOI: 10.1038/s41379-020-00722-5  0.312
2020 Hirsch D, Seyfried S, Staib T, Fiedler D, Sauer C, Ried T, Witt S, Rueckert F, Gaiser T. Newly established gastrointestinal cancer cell lines retain the genomic and immunophenotypic landscape of their parental cancers. Scientific Reports. 10: 17895. PMID 33087752 DOI: 10.1038/s41598-020-74797-0  0.322
2020 Lischka A, Doberstein N, Freitag-Wolf S, Koçak A, Gemoll T, Heselmeyer-Haddad K, Ried T, Auer G, Habermann JK. Genome instability profiles predict disease outcome in a cohort of 4,003 breast cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32522886 DOI: 10.1158/1078-0432.Ccr-20-0566  0.338
2020 Koçak A, Heselmeyer-Haddad K, Lischka A, Hirsch D, Fiedler D, Hu Y, Doberstein N, Torres I, Chen WD, Gertz EM, Schäffer AA, Freitag-Wolf S, Kirfel J, Auer G, Habermann JK, ... Ried T, et al. High levels of chromosomal copy number alterations and TP53 mutations correlate with poor outcome in younger breast cancer patients. The American Journal of Pathology. PMID 32416097 DOI: 10.1016/J.Ajpath.2020.04.015  0.4
2020 Galofré C, Gönül Geyik Ö, Asensio E, Wangsa D, Hirsch D, Parra C, Saez J, Mollà M, Yüce Z, Castells A, Ried T, Camps J. Tetraploidy-Associated Genetic Heterogeneity Confers Chemo-Radiotherapy Resistance to Colorectal Cancer Cells. Cancers. 12. PMID 32365785 DOI: 10.3390/Cancers12051118  0.397
2020 Braun R, Anthuber L, Hirsch D, Wangsa D, Lack J, McNeil NE, Heselmeyer-Haddad K, Torres I, Wangsa D, Brown MA, Tubbs A, Auslander N, Gertz EM, Brauer PR, Cam MC, ... ... Ried T, et al. Single cell-derived primary rectal carcinoma cell lines reflect intratumor heterogeneity associated with treatment response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32253233 DOI: 10.1158/1078-0432.Ccr-19-1984  0.316
2019 Wang L, Tang W, Yang S, He P, Wang J, Gaedcke J, Strobel P, Azizian A, Ried T, Gaida MM, Yfantis HG, Lee DH, Lal A, Van den Eynde BJ, Alexander HR, et al. NO /RUNX3/Kynurenine Metabolic Signaling Enhances Disease Aggressiveness in Pancreatic Cancer. International Journal of Cancer. PMID 31609478 DOI: 10.1002/Ijc.32733  0.369
2019 Ried T, Meijer GA, Harrison DJ, Grech G, Franch-Expósito S, Briffa R, Carvalho B, Camps J. The landscape of genomic copy number alterations in colorectal cancer and their consequences on gene expression levels and disease outcome. Molecular Aspects of Medicine. PMID 31365882 DOI: 10.1016/J.Mam.2019.07.007  0.405
2019 Wangsa D, Braun R, Stuelten CH, Brown M, Bauer KM, Emons G, Weston LA, Hu Y, Yang HH, Vila-Casadesús M, Lee MP, Brauer P, Warner L, Upender M, Hummon AB, ... ... Ried T, et al. Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells. Neoplasia (New York, N.Y.). 21: 721-729. PMID 31174021 DOI: 10.1016/J.Neo.2019.04.009  0.716
2019 Braun R, Ronquist S, Wangsa D, Chen H, Anthuber L, Gemoll T, Wangsa D, Koparde V, Hunn C, Habermann JK, Heselmeyer-Haddad K, Rajapakse I, Ried T. Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression. Neoplasia (New York, N.Y.). 21: 401-412. PMID 30909073 DOI: 10.1016/J.Neo.2019.02.003  0.528
2018 Torabi K, Erola P, Alvarez-Mora MI, Díaz-Gay M, Ferrer Q, Castells A, Castellví-Bel S, Milà M, Lozano J, Miró R, Ried T, Ponsa I, Camps J. Quantitative analysis of somatically-acquired and constitutive uniparental disomy in gastrointestinal cancers. International Journal of Cancer. PMID 30350313 DOI: 10.1002/ijc.31936  0.394
2018 Fiedler D, Heselmeyer-Haddad K, Hirsch D, Hernandez LS, Torres I, Wangsa D, Hu Y, Zapata L, Rueschoff J, Belle S, Ried T, Gaiser T. Single-cell genetic analysis of clonal dynamics in colorectal adenomas indicates CDX2 gain as a predictor of recurrence. International Journal of Cancer. PMID 30229897 DOI: 10.1002/ijc.31869  0.321
2018 Lai B, Tang Q, Jin W, Hu G, Wangsa D, Cui K, Stanton BZ, Ren G, Ding Y, Zhao M, Liu S, Song J, Ried T, Zhao K. Trac-looping measures genome structure and chromatin accessibility. Nature Methods. PMID 30150754 DOI: 10.1038/S41592-018-0107-Y  0.325
2018 Jowhar Z, Shachar S, Gudla PR, Wangsa D, Torres E, Russ JL, Pegoraro G, Ried T, Raznahan A, Misteli T. Effects of Human Sex Chromosome Dosage on Spatial Chromosome Organization. Molecular Biology of the Cell. mbcE18060359. PMID 30091656 DOI: 10.1091/Mbc.E18-06-0359  0.341
2018 Tsai PF, Dell'Orso S, Rodriguez J, Vivanco KO, Ko KD, Jiang K, Juan AH, Sarshad AA, Vian L, Tran M, Wangsa D, Wang AH, Perovanovic J, Anastasakis D, Ralston E, ... Ried T, et al. A Muscle-Specific Enhancer RNA Mediates Cohesin Recruitment and Regulates Transcription In trans. Molecular Cell. 71: 129-141.e8. PMID 29979962 DOI: 10.1016/J.Molcel.2018.06.008  0.313
2018 Raznahan A, Parikshak NN, Chandran V, Blumenthal JD, Clasen LS, Alexander-Bloch AF, Zinn AR, Wangsa D, Wise J, Murphy DGM, Bolton PF, Ried T, Ross J, Giedd JN, Geschwind DH. Sex-chromosome dosage effects on gene expression in humans. Proceedings of the National Academy of Sciences of the United States of America. PMID 29946024 DOI: 10.1073/Pnas.1802889115  0.371
2018 Wangsa D, Braun R, Schiefer M, Gertz EM, Bronder D, Quintanilla I, Padilla-Nash HM, Torres I, Hunn C, Warner L, Buishand FO, Hu Y, Hirsch D, Gaiser T, Camps J, ... ... Ried T, et al. The Evolution of Single Cell-derived Colorectal Cancer Cell Lines is Dominated by the Continued Selection of Tumor Specific Genomic Imbalances, Despite Random Chromosomal Instability. Carcinogenesis. PMID 29800151 DOI: 10.1093/Carcin/Bgy068  0.342
2018 Shukla V, Rao M, Zhang H, Beers J, Wangsa D, Wangsa D, Buishand FO, Wang Y, Yu Z, Stevenson H, Reardon E, McLoughlin KC, Kaufman A, Payabyab E, Hong JA, ... ... Ried T, et al. Identification of Novel Targets for Lung Cancer Therapy Using an Induced Pluripotent Stem Cell Model. Annals of the American Thoracic Society. 15: S127-S128. PMID 29676638 DOI: 10.1513/Annalsats.201707-610Mg  0.321
2018 Hu G, Cui K, Fang D, Hirose S, Wang X, Wangsa D, Jin W, Ried T, Liu P, Zhu J, Rothenberg EV, Zhao K. Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells. Immunity. 48: 227-242.e8. PMID 29466755 DOI: 10.1016/J.Immuni.2018.01.013  0.327
2018 Wangsa D, Quintanilla I, Torabi K, Vila-Casadesús M, Ercilla A, Klus G, Yuce Z, Galofré C, Cuatrecasas M, Lozano JJ, Agell N, Cimini D, Castells A, Ried T, Camps J. Near-tetraploid cancer cells show chromosome instability triggered by replication stress and exhibit enhanced invasiveness. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201700247RR. PMID 29452566 DOI: 10.1096/Fj.201700247Rr  0.367
2018 Jowhar Z, Gudla P, Shachar S, Wangsa D, Russ JL, Pegoraro G, Ried T, Raznahan A, Misteli T. HiCTMap: Detection and Analysis of Chromosome Territory Structure and Position by High-throughput Imaging. Methods (San Diego, Calif.). PMID 29408376 DOI: 10.1016/J.Ymeth.2018.01.013  0.334
2018 Torres IM, Hernandez L, Tzeng J, Schwartz R, Schaffer A, Gertz EM, Hirsch D, Brower S, Sanchez M, Auer G, Heselmeyer-Haddad K, Ried T. Abstract 2189: Genomic dynamics in breast cancer progression analyzed by miFISH analysis Tumor Biology. DOI: 10.1158/1538-7445.Am2018-2189  0.334
2017 Kidder BL, He R, Wangsa D, Padilla-Nash HM, Bernardo MM, Sheng S, Ried T, Zhao K. SMYD5 controls heterochromatin and chromosome integrity during embryonic stem cell differentiation. Cancer Research. PMID 28951459 DOI: 10.1158/0008-5472.Can-17-0828  0.488
2017 Buishand FO, Cardin E, Hu Y, Ried T. Trichostatin A preferentially reverses the upregulation of gene expression levels induced by gain of chromosome 7 in colorectal cancer cell lines. Genes, Chromosomes & Cancer. PMID 28940826 DOI: 10.1002/Gcc.22505  0.539
2017 Shukla V, Rao M, Zhang H, Beers J, Wangsa D, Wangsa D, Buishand FO, Wang Y, Yu Z, Stevenson H, Reardon E, McLoughlin KC, Kaufman A, Payabyab E, Hong JA, ... ... Ried T, et al. ASXL3 is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer. Cancer Research. PMID 28935813 DOI: 10.1158/0008-5472.Can-17-0570  0.351
2017 Chen C, Choudhury S, Wangsa D, Lescott CJ, Wilkins DJ, Sripadhan P, Liu X, Wangsa D, Ried T, Moskaluk C, Wick MJ, Glasgow E, Schlegel R, Agarwal S. A multiplex preclinical model for adenoid cystic carcinoma of the salivary gland identifies regorafenib as a potential therapeutic drug. Scientific Reports. 7: 11410. PMID 28900283 DOI: 10.1038/S41598-017-11764-2  0.345
2017 Rozenblum E, Sotelo-Silveira JR, Kim GY, Zhu JY, Lau CC, McNeil N, Korolevich S, Liao H, Cherry JM, Munroe DJ, Ried T, Meltzer PS, Kuehl WM, Roschke AV. Novel near-diploid ovarian cancer cell line derived from a highly aneuploid metastatic ovarian tumor. Plos One. 12: e0182610. PMID 28787462 DOI: 10.1371/Journal.Pone.0182610  0.481
2017 Yang Y, Vocke CD, Ricketts CJ, Wei D, Padilla-Nash HM, Lang M, Sourbier C, Killian JK, Boyle SL, Worrell R, Meltzer PS, Ried T, Merino MJ, Metwalli AR, Linehan WM. Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276). Genes, Chromosomes & Cancer. PMID 28736828 DOI: 10.1002/Gcc.22476  0.323
2017 McNamara G, Difilippantonio M, Ried T, Bieber FR. Microscopy and Image Analysis. Current Protocols in Human Genetics. 94: 4.4.1-4.4.89. PMID 28696557 DOI: 10.1002/cphg.42  0.574
2017 Yuan H, Krawczyk E, Blancato J, Albanese C, Zhou D, Wang N, Paul S, Alkhilaiwi F, Palechor-Ceron N, Dakic A, Fang S, Choudhary S, Hou TW, Zheng YL, Haddad BR, ... ... Ried T, et al. HPV positive neuroendocrine cervical cancer cells are dependent on Myc but not E6/E7 viral oncogenes. Scientific Reports. 7: 45617. PMID 28378747 DOI: 10.1038/Srep45617  0.364
2017 Torabi K, Wangsa D, Ponsa I, Brown M, Bosch A, Vila-Casadesús M, Karpova TS, Calvo M, Castells A, Miró R, Ried T, Camps J. Transcription-dependent radial distribution of TCF7L2 regulated genes in chromosome territories. Chromosoma. PMID 28343235 DOI: 10.1007/S00412-017-0629-6  0.347
2017 Seaman L, Chen H, Brown M, Wangsa D, Patterson G, Camps J, Omenn GS, Ried T, Rajapakse I. Nucleome Analysis Reveals Structure-function Relationships for Colon Cancer. Molecular Cancer Research : McR. PMID 28258094 DOI: 10.1158/1541-7786.Mcr-16-0374  0.405
2017 Wangsa D, Schiefer M, Bronder D, Padilla-Nash H, Torres I, Warner L, Hu Y, Gertz EM, Schwartz R, Schäffer AA, Hirsch D, Gaiser T, Meyer R, Camps J, Heselmeyer-Haddad K, ... Ried T, et al. Abstract 4387: The clonal composition of colorectal cancer cell lines is defined by the maintenance of specific genomic imbalances, not by ongoing chromosomal instability Cancer Research. 77: 4387-4387. DOI: 10.1158/1538-7445.Am2017-4387  0.473
2017 Hirsch DD, Wangsa D, Hu Y, Zhu J, Petersen D, Edelman DC, Meltzer PS, Tran B, Heselmeyer-Haddad K, Ried T, Gaiser T. Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis Cancer Research. 77: 1438-1438. DOI: 10.1158/1538-7445.Am2017-1438  0.356
2016 McNeil NE, Padilla-Nash HM, Buishand FO, Hue Y, Ried T. Novel Mouse Model Recapitulates Genome and Transcriptome Alterations in Human Colorectal Carcinomas. Genes, Chromosomes & Cancer. PMID 27750367 DOI: 10.1002/gcc.22426  0.42
2016 Wang J, Yang S, He P, Schetter A, Gaedcke J, Ghadimi BM, Ried T, Yfantis HG, Lee DH, Gaida MM, Hanna N, Alexander HR, Hussain SP. Endothelial Nitric Oxide Synthase Traffic Inducer (NOSTRIN) is a Negative Regulator of Disease Aggressiveness in Pancreatic Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27401251 DOI: 10.1158/1078-0432.Ccr-16-0511  0.343
2016 Wang J, He P, Gaida M, Yang S, Schetter AJ, Gaedcke J, Ghadimi BM, Ried T, Yfantis H, Lee D, Weiss JM, Stauffer J, Hanna N, Alexander HR, Hussain SP. Inducible nitric oxide synthase enhances disease aggressiveness in pancreatic cancer. Oncotarget. PMID 27367029 DOI: 10.18632/Oncotarget.10323  0.355
2016 Yang S, He P, Wang J, Schetter A, Tang W, Funamizu N, Yanaga K, Uwagawa T, Satoskar AR, Gaedcke J, Bernhardt M, Ghadimi BM, Gaida MM, Bergmann F, Werner J, ... Ried T, et al. A novel MIF signaling pathway drives the malignant character of pancreatic cancer by targeting NR3C2. Cancer Research. PMID 27197190 DOI: 10.1158/0008-5472.Can-15-2841  0.347
2016 Yang Y, Vocke CD, Ricketts CJ, Wei D, Padilla-Nash HM, Boyle SL, Worrell R, Ried T, Merino MJ, Linehan WM. Abstract A19: A novel cell line model for chromophobe renal cell carcinoma, UOK276, derived from an aggressive sarcomatoid differentiated tumor Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-A19  0.473
2016 Emons G, Spitzner M, Reineke S, Kramer F, Rave-Fraenk M, Gaedcke J, Ghadimi M, Ried T, Grade M. Abstract 1653: A novel role for Wnt/β-catenin signaling in mediating resistance of colorectal cancer to chemoradiotherapy Cancer Research. 76: 1653-1653. DOI: 10.1158/1538-7445.Am2016-1653  0.331
2015 Gemoll T, Auer G, Ried T, Habermann JK. Genetic Instability and Disease Prognostication. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 200: 81-94. PMID 26376873 DOI: 10.1007/978-3-319-20291-4_4  0.415
2015 Torabi K, Miró R, Fernández-Jiménez N, Quintanilla I, Ramos L, Prat E, Del Rey J, Pujol N, Killian JK, Meltzer PS, Fernández PL, Ried T, Lozano JJ, Camps J, Ponsa I. Patterns of somatic uniparental disomy identify novel tumor suppressor genes in colorectal cancer. Carcinogenesis. PMID 26243311 DOI: 10.1093/Carcin/Bgv115  0.4
2015 Nicholson JM, Macedo JC, Mattingly AJ, Wangsa D, Camps J, Lima V, Gomes AM, Dória S, Ried T, Logarinho E, Cimini D. Chromosome mis-segregation and cytokinesis failure in trisomic human cells. Elife. 4. PMID 25942454 DOI: 10.7554/Elife.05068  0.4
2015 Athwal RK, Walkiewicz MP, Baek S, Fu S, Bui M, Camps J, Ried T, Sung MH, Dalal Y. CENP-A nucleosomes localize to transcription factor hotspots and subtelomeric sites in human cancer cells. Epigenetics & Chromatin. 8: 2. PMID 25788983 DOI: 10.1186/1756-8935-8-2  0.405
2015 Chen H, Comment N, Chen J, Ronquist S, Hero A, Ried T, Rajapakse I. Chromosome conformation of human fibroblasts grown in 3-dimensional spheroids. Nucleus (Austin, Tex.). 6: 55-65. PMID 25738643 DOI: 10.1080/19491034.2014.1003745  0.315
2015 Camps J, Erdos MR, Ried T. The role of lamin B1 for the maintenance of nuclear structure and function. Nucleus (Austin, Tex.). 6: 8-14. PMID 25602590 DOI: 10.1080/19491034.2014.1003510  0.338
2015 Achyut BR, Bader D, Robles A, Darawarlee W, Harris C, Ried T, Yang L. Abstract B48: Inflammation-mediated genetic and epigenetic alterations drive cancer development in the neighboring epithelium upon stromal abrogation of TGF-β signaling Cancer Research. 75. DOI: 10.1158/1538-7445.Chtme14-B48  0.394
2015 Wang J, He P, Gaida MM, Yang S, Schetter A, Gaedcke J, Ghadimi M, Ried T, Yfantis HG, Lee DH, Weiss JM, Hanna N, Alexander HR, Hussain SP. Abstract 923: Nitric oxide signaling pathway as a pathogenic driver in pancreatic cancer Cancer Research. 75: 923-923. DOI: 10.1158/1538-7445.Am2015-923  0.385
2015 Yang S, He P, Wang J, Schetter A, Tang W, Funamizu N, Gaedcke J, Ghadimi M, Gaida M, Ried T, Hannah N, Alexander HR, Hussain SP. Abstract 922: Macrophage migration inhibitory factor (MIF) and miR-301b interactively enhance disease aggressiveness by targeting NR3C2 (nuclear receptor subfamily group c member 2) in human pancreatic cancer Cancer Research. 75: 922-922. DOI: 10.1158/1538-7445.Am2015-922  0.32
2015 Hernandez LS, Bradley A, Gaiser T, Andersson S, Gertz EM, Chowdhury SA, Schwartz R, Schäffer A, Heselmeyer-Haddad K, Ried T. Abstract 4833: Single-cell genetic analysis reveals insights into clonal development of cervical cancer and confirms TERC as an early and dominant aberration Cancer Research. 75: 4833-4833. DOI: 10.1158/1538-7445.Am2015-4833  0.341
2015 Michael Ghadimi B, Ried T. Chromosomal Instability in Cancer Cells Chromosomal Instability in Cancer Cells. 1-224. DOI: 10.1007/978-3-319-20291-4  0.384
2014 Hirsch D, Hu Y, Ried T, Moll R, Gaiser T. Transcriptome profiling of LGR5 positive colorectal cancer cells. Genomics Data. 2: 212-5. PMID 26484096 DOI: 10.1016/j.gdata.2014.06.005  0.303
2014 Kirshenbaum AS, Petrik A, Walsh R, Kirby TL, Vepa S, Wangsa D, Ried T, Metcalfe DD. A ten-year retrospective analysis of the distribution, use and phenotypic characteristics of the LAD2 human mast cell line. International Archives of Allergy and Immunology. 164: 265-70. PMID 25195635 DOI: 10.1159/000365729  0.308
2014 Heselmeyer-Haddad KM, Berroa Garcia LY, Bradley A, Hernandez L, Hu Y, Habermann JK, Dumke C, Thorns C, Perner S, Pestova E, Burke C, Chowdhury SA, Schwartz R, Schäffer AA, Paris PL, ... Ried T, et al. Single-cell genetic analysis reveals insights into clonal development of prostate cancers and indicates loss of PTEN as a marker of poor prognosis. The American Journal of Pathology. 184: 2671-86. PMID 25131421 DOI: 10.1016/J.Ajpath.2014.06.030  0.466
2014 Chowdhury SA, Shackney SE, Heselmeyer-Haddad K, Ried T, Schäffer AA, Schwartz R. Algorithms to model single gene, single chromosome, and whole genome copy number changes jointly in tumor phylogenetics. Plos Computational Biology. 10: e1003740. PMID 25078894 DOI: 10.1371/Journal.Pcbi.1003740  0.461
2014 Zhang Y, Calado R, Rao M, Hong JA, Meeker AK, Dumitriu B, Atay S, McCormick PJ, Garfield SH, Wangsa D, Padilla-Nash HM, Burkett S, Zhang M, Kunst TF, Peterson NR, ... ... Ried T, et al. Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas. Plos One. 9: e101010. PMID 24983628 DOI: 10.1371/Journal.Pone.0101010  0.335
2014 Camps J, Wangsa D, Falke M, Brown M, Case CM, Erdos MR, Ried T. Loss of lamin B1 results in prolongation of S phase and decondensation of chromosome territories. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3423-34. PMID 24732130 DOI: 10.1096/Fj.14-250456  0.469
2014 Akagi K, Li J, Broutian TR, Padilla-Nash H, Xiao W, Jiang B, Rocco JW, Teknos TN, Kumar B, Wangsa D, He D, Ried T, Symer DE, Gillison ML. Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability. Genome Research. 24: 185-99. PMID 24201445 DOI: 10.1101/Gr.164806.113  0.347
2014 Spitzner M, Roesler B, Bielfeld C, Emons G, Gaedcke J, Wolff HA, Rave-Fränk M, Kramer F, Beissbarth T, Kitz J, Wienands J, Ghadimi BM, Ebner R, Ried T, Grade M. STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo. International Journal of Cancer. Journal International Du Cancer. 134: 997-1007. PMID 23934972 DOI: 10.1002/Ijc.28429  0.327
2014 Tang J, Li Y, Lyon K, Camps J, Dalton S, Ried T, Zhao S. Cancer driver-passenger distinction via sporadic human and dog cancer comparison: a proof-of-principle study with colorectal cancer. Oncogene. 33: 814-22. PMID 23416983 DOI: 10.1038/Onc.2013.17  0.457
2014 Wang J, He P, Gaida MM, Yang S, Schetter A, Gaedcke J, Ghadimi M, Ried T, Yfantis HG, Lee DH, Weiss JM, Stauffer J, Hanna N, Alexander HR, Hussain SP. Abstract 926: Nitric oxide enhances tumor progression and disease aggressiveness in pancreatic cancer Cancer Research. 74: 926-926. DOI: 10.1158/1538-7445.Am2014-926  0.384
2014 Chowdhury SA, Subramanian A, Schäffer AA, Shackney SE, Wangsa D, Heselmeyer-Haddad K, Ried T, Schwartz R. Abstract 5338: Inferring evolutionary models of tumor progression from single-cell heterogeneity data Cancer Research. 74: 5338-5338. DOI: 10.1158/1538-7445.Am2014-5338  0.434
2014 Yang S, He P, Wang J, Schetter A, Funamizu N, Yanaga K, Gaedcke J, Ghadimi BM, Gaida MM, Ried T, Hanna N, Alexander HR, Hussain SP. Abstract 4363: Macrophage migration inhibitory factor (MIF) and miR-301b interactively enhance disease aggressiveness by targeting NR3C2 in human pancreatic cancer Cancer Research. 74: 4363-4363. DOI: 10.1158/1538-7445.Am2014-4363  0.328
2014 Emons G, Spitzner M, Reineke S, Möller J, Kendziorra E, Beissbarth T, Rave-Fraenk M, Gaedcke J, Ried T, Ghadimi M, Grade M. Abstract 3946: Wnt/ß-catenin signaling mediates resistance of colorectal cancer cells to chemoradiotherapy Cancer Research. 74: 3946-3946. DOI: 10.1158/1538-7445.Am2014-3946  0.348
2013 Gemoll T, Habermann JK, Becker S, Szymczak S, Upender MB, Bruch HP, Hellman U, Ried T, Auer G, Jörnvall H, Roblick UJ. Chromosomal aneuploidy affects the global proteome equilibrium of colorectal cancer cells. Analytical Cellular Pathology (Amsterdam). 36: 149-61. PMID 24464829 DOI: 10.3233/Acp-140088  0.534
2013 Padilla-Nash HM, McNeil NE, Yi M, Nguyen QT, Hu Y, Wangsa D, Mack DL, Hummon AB, Case C, Cardin E, Stephens R, Difilippantonio MJ, Ried T. Aneuploidy, oncogene amplification and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells. Carcinogenesis. 34: 1929-39. PMID 23619298 DOI: 10.1093/Carcin/Bgt138  0.799
2013 Winkler T, Hong SG, Decker JE, Morgan MJ, Wu C, Hughes WM, Yang Y, Wangsa D, Padilla-Nash HM, Ried T, Young NS, Dunbar CE, Calado RT. Defective telomere elongation and hematopoiesis from telomerase-mutant aplastic anemia iPSCs. The Journal of Clinical Investigation. 123: 1952-63. PMID 23585473 DOI: 10.1172/Jci67146  0.332
2013 Gerling M, Nousiainen K, Hautaniemi S, Krüger S, Fritzsche B, Homann N, Bruch HP, Auer G, Roblick UJ, Ried T, Habermann JK. Aneuploidy-associated gene expression signatures characterize malignant transformation in ulcerative colitis. Inflammatory Bowel Diseases. 19: 691-703. PMID 23455720 DOI: 10.1097/MIB.0b013e31827eeaa4  0.333
2013 Camps J, Pitt JJ, Emons G, Hummon AB, Case CM, Grade M, Jones TL, Nguyen QT, Ghadimi BM, Beissbarth T, Difilippantonio MJ, Caplen NJ, Ried T. Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer. Cancer Research. 73: 2003-13. PMID 23319804 DOI: 10.1158/0008-5472.CAN-12-3159  0.796
2013 Hirsch D, Kemmerling R, Davis S, Camps J, Meltzer PS, Ried T, Gaiser T. Chromothripsis and focal copy number alterations determine poor outcome in malignant melanoma. Cancer Research. 73: 1454-60. PMID 23271725 DOI: 10.1158/0008-5472.Can-12-0928  0.448
2013 Hirsch DD, Barker N, McNeil N, Hu Y, Camps J, McKinnon K, Clevers H, Ried T, Gaiser T. Abstract 5023: Stem cell hypothesis and function of Lgr5 in the development of colon cancer. Cancer Research. 73: 5023-5023. DOI: 10.1158/1538-7445.Am2013-5023  0.41
2013 Emons G, Möller J, Spitzner M, Kendziorra E, Gaedcke J, Rave-Fränk M, Pukrop T, Ghadimi M, Ried T, Grade M. Abstract 1588: Canonical Wnt signaling mediates resistance of colorectal cancer cells to radiation therapy. Cancer Research. 73: 1588-1588. DOI: 10.1158/1538-7445.Am2013-1588  0.331
2012 Coleman AE, McNeil N, Kovalchuck AL, Wangsa D, Ried T, Wang H. Cellular exposure to muscle relaxants and propofol could lead to genomic instability in vitro. Journal of Biomedical Research. 26: 117-24. PMID 23554740 DOI: 10.1016/S1674-8301(12)60021-9  0.314
2012 Heselmeyer-Haddad K, Berroa Garcia LY, Bradley A, Ortiz-Melendez C, Lee WJ, Christensen R, Prindiville SA, Calzone KA, Soballe PW, Hu Y, Chowdhury SA, Schwartz R, Schäffer AA, Ried T. Single-cell genetic analysis of ductal carcinoma in situ and invasive breast cancer reveals enormous tumor heterogeneity yet conserved genomic imbalances and gain of MYC during progression. The American Journal of Pathology. 181: 1807-22. PMID 23062488 DOI: 10.1016/J.Ajpath.2012.07.012  0.356
2012 Gaedcke J, Grade M, Camps J, Søkilde R, Kaczkowski B, Schetter AJ, Difilippantonio MJ, Harris CC, Ghadimi BM, Møller S, Beissbarth T, Ried T, Litman T. The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4919-30. PMID 22850566 DOI: 10.1158/1078-0432.Ccr-12-0016  0.628
2012 Ried T, Gaiser T. A recurrent fusion gene in high-grade endometrial stromal sarcoma: a new tool for diagnosis and therapy? Genome Medicine. 4: 20. PMID 22429906 DOI: 10.1186/gm319  0.333
2012 Ried T, Hu Y, Difilippantonio MJ, Ghadimi BM, Grade M, Camps J. The consequences of chromosomal aneuploidy on the transcriptome of cancer cells. Biochimica Et Biophysica Acta. 1819: 784-93. PMID 22426433 DOI: 10.1016/J.Bbagrm.2012.02.020  0.748
2012 Hummon AB, Pitt JJ, Camps J, Emons G, Skube SB, Huppi K, Jones TL, Beissbarth T, Kramer F, Grade M, Difilippantonio MJ, Ried T, Caplen NJ. Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells. Molecular Cancer. 11: 1. PMID 22216762 DOI: 10.1186/1476-4598-11-1  0.78
2012 Padilla-Nash HM, Hathcock K, McNeil NE, Mack D, Hoeppner D, Ravin R, Knutsen T, Yonescu R, Wangsa D, Dorritie K, Barenboim L, Hu Y, Ried T. Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances. Genes, Chromosomes & Cancer. 51: 353-74. PMID 22161874 DOI: 10.1002/Gcc.21921  0.5
2012 Sharon E, Zhang J, Hollevoet K, Steinberg SM, Pastan I, Onda M, Gaedcke J, Ghadimi BM, Ried T, Hassan R. Serum mesothelin and megakaryocyte potentiating factor in pancreatic and biliary cancers. Clinical Chemistry and Laboratory Medicine : Cclm / Fescc. 50: 721-5. PMID 22149739 DOI: 10.1515/Cclm.2011.816  0.303
2012 Calado RT, Cooper JN, Padilla-Nash HM, Sloand EM, Wu CO, Scheinberg P, Ried T, Young NS. Short telomeres result in chromosomal instability in hematopoietic cells and precede malignant evolution in human aplastic anemia. Leukemia. 26: 700-7. PMID 22005790 DOI: 10.1038/leu.2011.272  0.345
2012 Olnes MJ, Poon A, Miranda SJ, Pfannes L, Tucker Z, Loeliger K, Padilla-Nash H, Yau YY, Ried T, Leitman SF, Young NS, Sloand EM. Effects of granulocyte-colony-stimulating factor on Monosomy 7 aneuploidy in healthy hematopoietic stem cell and granulocyte donors. Transfusion. 52: 537-41. PMID 21883270 DOI: 10.1111/J.1537-2995.2011.03313.X  0.333
2012 Goldenberg DM, Zagzag D, Heselmeyer-Haddad KM, Berroa Garcia LY, Ried T, Loo M, Chang CH, Gold DV. Horizontal transmission and retention of malignancy, as well as functional human genes, after spontaneous fusion of human glioblastoma and hamster host cells in vivo. International Journal of Cancer. Journal International Du Cancer. 131: 49-58. PMID 21796629 DOI: 10.1002/Ijc.26327  0.329
2012 Hilgenfeld E, Padilla-Nash H, Schröck E, Ried T, Haas OA, Serve H. Spectral Karyotyping (SKY) of Hematologic Malignancies. Methods in Molecular Medicine. 55: 65-79. PMID 21312104 DOI: 10.1385/1-59259-074-8:65  0.345
2012 Zhang G, Hussain SP, He P, Gaedcke J, Ghadimi MB, Ried T, Yfantis HG, Lee DH, Hannah N, Alexander HR. Abstract A103: FOXL1 suppresses tumor growth and invasiveness and predicts clinical outcome in human pancreatic ductal adenocarcinoma (PDAC). Cancer Research. 72. DOI: 10.1158/1538-7445.Panca2012-A103  0.324
2012 Grade M, Eimer C, Emons G, Kendziorra E, Spitzner M, Gaedcke J, Wolff H, Beissbarth T, Ried T, Pukrop T, Ghadimi M. Abstract 5729: The Wnt transcription factor TCF4 mediates resistance of colorectal cancer cells to (chemo-) radiotherapy in a β-catenin-independent manner Cancer Research. 72: 5729-5729. DOI: 10.1158/1538-7445.Am2012-5729  0.364
2012 Bradley A, Heselmeyer-Haddad K, Gaiser T, Lee W, Schaffer AA, Andersson S, Ried T. Abstract 2107: Clonal patterns of chromosomal aberrations in cervical cancers and precursor lesions Cancer Research. 72: 2107-2107. DOI: 10.1158/1538-7445.Am2012-2107  0.406
2012 Ried T, Difilippantonio MJ. Characterization of chromosomal translocations in mouse models of hematological malignancies using spectral karyotyping, fish, and immunocytochemistry Genetically Engineered Mice For Cancer Research: Design, Analysis, Pathways, Validation and Pre-Clinical Testing. 193-207. DOI: 10.1007/978-0-387-69805-2_9  0.683
2011 Habermann JK, Bündgen NK, Gemoll T, Hautaniemi S, Lundgren C, Wangsa D, Doering J, Bruch HP, Nordstroem B, Roblick UJ, Jörnvall H, Auer G, Ried T. Genomic instability influences the transcriptome and proteome in endometrial cancer subtypes. Molecular Cancer. 10: 132. PMID 22040021 DOI: 10.1186/1476-4598-10-132  0.472
2011 Derfoul A, Juan AH, Difilippantonio MJ, Palanisamy N, Ried T, Sartorelli V. Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase. Carcinogenesis. 32: 1607-14. PMID 21828058 DOI: 10.1093/carcin/bgr184  0.621
2011 Gemoll T, Roblick UJ, Szymczak S, Braunschweig T, Becker S, Igl BW, Bruch HP, Ziegler A, Hellman U, Difilippantonio MJ, Ried T, Jörnvall H, Auer G, Habermann JK. HDAC2 and TXNL1 distinguish aneuploid from diploid colorectal cancers. Cellular and Molecular Life Sciences : Cmls. 68: 3261-74. PMID 21290163 DOI: 10.1007/S00018-011-0628-3  0.682
2011 Liu Z, Yang X, Li Z, McMahon C, Sizer C, Barenboim-Stapleton L, Bliskovsky V, Mock B, Ried T, London WB, Maris J, Khan J, Thiele CJ. CASZ1, a candidate tumor-suppressor gene, suppresses neuroblastoma tumor growth through reprogramming gene expression. Cell Death and Differentiation. 18: 1174-83. PMID 21252912 DOI: 10.1038/Cdd.2010.187  0.336
2011 Habermann JK, Brucker CA, Freitag-Wolf S, Heselmeyer-Haddad K, Krüger S, Barenboim L, Downing T, Bruch HP, Auer G, Roblick UJ, Ried T. Genomic instability and oncogene amplifications in colorectal adenomas predict recurrence and synchronous carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 24: 542-55. PMID 21102417 DOI: 10.1055/S-0031-1285737  0.41
2011 Grade M, Hummon AB, Camps J, Emons G, Spitzner M, Gaedcke J, Hoermann P, Ebner R, Becker H, Difilippantonio MJ, Ghadimi BM, Beissbarth T, Caplen NJ, Ried T. A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets. International Journal of Cancer. Journal International Du Cancer. 128: 1069-79. PMID 20473941 DOI: 10.1002/Ijc.25453  0.77
2011 McNeil N, Montagna C, Difilippantonio MJ, Ried T. Comparative cancer cytogenetics Atlas of Genetics and Cytogenetics in Oncology and Haematology. DOI: 10.4267/2042/38033  0.745
2011 Hirsch D, Stapleton M, Ried T, Camps J, Gaiser T. Abstract 3073: Isothermal whole genome amplification of FFPE samples to detect copy number changes in the progression from colonic adenoma to carcinoma Cancer Research. 71: 3073-3073. DOI: 10.1158/1538-7445.Am2011-3073  0.361
2011 Grade M, Spitzner M, Emons G, Kramer F, Gaedcke J, Rave-Fränk M, Scharf J, Burfeind P, Becker H, Beissbarth T, Ghadimi BM, Ried T. Abstract 2508: Identification of potential relevant pathways and genes for resistance to chemoradiotherapy in colorectal cancer cells Cancer Research. 71: 2508-2508. DOI: 10.1158/1538-7445.Am2011-2508  0.426
2010 Mettu RK, Wan YW, Habermann JK, Ried T, Guo NL. A 12-gene genomic instability signature predicts clinical outcomes in multiple cancer types. The International Journal of Biological Markers. 25: 219-28. PMID 21161944 DOI: 10.5301/Jbm.2010.6079  0.346
2010 Spitzner M, Emons G, Kramer F, Gaedcke J, Rave-Fränk M, Scharf JG, Burfeind P, Becker H, Beissbarth T, Ghadimi BM, Ried T, Grade M. A gene expression signature for chemoradiosensitivity of colorectal cancer cells. International Journal of Radiation Oncology, Biology, Physics. 78: 1184-92. PMID 20970032 DOI: 10.1016/j.ijrobp.2010.06.023  0.329
2010 Cheng L, Zhou Z, Flesken-Nikitin A, Toshkov IA, Wang W, Camps J, Ried T, Nikitin AY. Rb inactivation accelerates neoplastic growth and substitutes for recurrent amplification of cIAP1, cIAP2 and Yap1 in sporadic mammary carcinoma associated with p53 deficiency. Oncogene. 29: 5700-11. PMID 20676140 DOI: 10.1038/Onc.2010.300  0.433
2010 Fishler T, Li YY, Wang RH, Kim HS, Sengupta K, Vassilopoulos A, Lahusen T, Xu X, Lee MH, Liu Q, Elledge SJ, Ried T, Deng CX. Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 and p53. Oncogene. 29: 4007-17. PMID 20473325 DOI: 10.1038/onc.2010.163  0.316
2010 Takizawa M, Kim JS, Tessarollo L, McNeil N, Waldschmidt TJ, Casellas R, Ried T, Janz S. Genetic reporter system for oncogenic Igh-Myc translocations in mice. Oncogene. 29: 4113-20. PMID 20453890 DOI: 10.1038/onc.2010.150  0.372
2010 Yang Y, Valera VA, Padilla-Nash HM, Sourbier C, Vocke CD, Vira MA, Abu-Asab MS, Bratslavsky G, Tsokos M, Merino MJ, Pinto PA, Srinivasan R, Ried T, Neckers L, Linehan WM. UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer. Cancer Genetics and Cytogenetics. 196: 45-55. PMID 19963135 DOI: 10.1016/J.Cancergencyto.2009.08.018  0.315
2010 Knutsen T, Padilla-Nash HM, Wangsa D, Barenboim-Stapleton L, Camps J, McNeil N, Difilippantonio MJ, Ried T. Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines. Genes, Chromosomes & Cancer. 49: 204-23. PMID 19927377 DOI: 10.1002/Gcc.20730  0.745
2010 Li Y, Fischler T, Xu X, Wang R, Kim H, Sengupta K, Vassilopoulos A, Lahusen T, Liu Q, Elledge S, Ried T, Deng C. Abstract 1964: Genetic instability and mammary tumor formation in mice carrying mammary-specific disruption of Chk1 Cancer Research. 70: 1964-1964. DOI: 10.1158/1538-7445.Am10-1964  0.437
2010 Berroa-Garcia LY, Ortiz-Melendez C, Valentine SV, Tewelde S, Christensen R, Calzone K, Schaffer A, Prindiville S, Ried T, Heselmeyer-Haddad K. Abstract 1757: Patterns of clonal chromosomal aberrations in invasive breast cancer compared to adjacent DCIS lesions detected by a ten-probe FISH panel Cancer Research. 70: 1757-1757. DOI: 10.1158/1538-7445.Am10-1757  0.404
2009 Gertz EM, Sengupta K, Difilippantonio MJ, Ried T, Schäffer AA. Evaluating annotations of an Agilent expression chip suggests that many features cannot be interpreted. Bmc Genomics. 10: 566. PMID 19948035 DOI: 10.1186/1471-2164-10-566  0.665
2009 Robbiani DF, Bunting S, Feldhahn N, Bothmer A, Camps J, Deroubaix S, McBride KM, Klein IA, Stone G, Eisenreich TR, Ried T, Nussenzweig A, Nussenzweig MC. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations. Molecular Cell. 36: 631-41. PMID 19941823 DOI: 10.1016/J.Molcel.2009.11.007  0.34
2009 Andersson S, Sowjanya P, Wangsa D, Hjerpe A, Johansson B, Auer G, Gravitt PE, Larsson C, Wallin KL, Ried T, Heselmeyer-Haddad K. Detection of genomic amplification of the human telomerase gene TERC, a potential marker for triage of women with HPV-positive, abnormal Pap smears. The American Journal of Pathology. 175: 1831-47. PMID 19880826 DOI: 10.2353/Ajpath.2009.090122  0.386
2009 Difilippantonio MJ, Ghadimi BM, Howard T, Camps J, Nguyen QT, Ferris DK, Sackett DL, Ried T. Nucleation capacity and presence of centrioles define a distinct category of centrosome abnormalities that induces multipolar mitoses in cancer cells. Environmental and Molecular Mutagenesis. 50: 672-96. PMID 19768832 DOI: 10.1002/Em.20532  0.752
2009 Ried T. Homage to Theodor Boveri (1862-1915): Boveri's theory of cancer as a disease of the chromosomes, and the landscape of genomic imbalances in human carcinomas. Environmental and Molecular Mutagenesis. 50: 593-601. PMID 19739242 DOI: 10.1002/em.20526  0.312
2009 Camps J, Nguyen QT, Padilla-Nash HM, Knutsen T, McNeil NE, Wangsa D, Hummon AB, Grade M, Ried T, Difilippantonio MJ. Integrative genomics reveals mechanisms of copy number alterations responsible for transcriptional deregulation in colorectal cancer. Genes, Chromosomes & Cancer. 48: 1002-17. PMID 19691111 DOI: 10.1002/Gcc.20699  0.809
2009 Grade M, Gaedcke J, Wangsa D, Varma S, Beckmann J, Liersch T, Hess C, Becker H, Difilippantonio MJ, Ried T, Ghadimi BM. Chromosomal copy number changes of locally advanced rectal cancers treated with preoperative chemoradiotherapy. Cancer Genetics and Cytogenetics. 193: 19-28. PMID 19602460 DOI: 10.1016/j.cancergencyto.2009.03.016  0.693
2009 Callén E, Bunting S, Huang CY, Difilippantonio MJ, Wong N, Khor B, Mahowald G, Kruhlak MJ, Ried T, Sleckman BP, Nussenzweig A. Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG. Cell Cycle (Georgetown, Tex.). 8: 2408-12. PMID 19556863 DOI: 10.4161/Cc.8.15.9085  0.67
2009 Swanton C, Nicke B, Schuett M, Eklund AC, Ng C, Li Q, Hardcastle T, Lee A, Roy R, East P, Kschischo M, Endesfelder D, Wylie P, Kim SN, Chen JG, ... ... Ried T, et al. Chromosomal instability determines taxane response. Proceedings of the National Academy of Sciences of the United States of America. 106: 8671-6. PMID 19458043 DOI: 10.1073/Pnas.0811835106  0.481
2009 Liersch T, Grade M, Gaedcke J, Varma S, Difilippantonio MJ, Langer C, Hess CF, Becker H, Ried T, Ghadimi BM. Preoperative chemoradiotherapy in locally advanced rectal cancer: correlation of a gene expression-based response signature with recurrence. Cancer Genetics and Cytogenetics. 190: 57-65. PMID 19380020 DOI: 10.1016/j.cancergencyto.2008.11.011  0.664
2009 Habermann JK, Doering J, Hautaniemi S, Roblick UJ, Bündgen NK, Nicorici D, Kronenwett U, Rathnagiriswaran S, Mettu RK, Ma Y, Krüger S, Bruch HP, Auer G, Guo NL, Ried T. The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome. International Journal of Cancer. Journal International Du Cancer. 124: 1552-64. PMID 19101988 DOI: 10.1002/Ijc.24017  0.388
2009 Dierov J, Sanchez PV, Burke BA, Padilla-Nash H, Putt ME, Ried T, Carroll M. BCR/ABL induces chromosomal instability after genotoxic stress and alters the cell death threshold. Leukemia. 23: 279-86. PMID 19020542 DOI: 10.1038/Leu.2008.308  0.413
2008 Garman KS, Acharya CR, Edelman E, Grade M, Gaedcke J, Sud S, Barry W, Diehl AM, Provenzale D, Ginsburg GS, Ghadimi BM, Ried T, Nevins JR, Mukherjee S, Hsu D, et al. A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities. Proceedings of the National Academy of Sciences of the United States of America. 105: 19432-7. PMID 19050079 DOI: 10.1073/Pnas.0806674105  0.395
2008 Sengupta K, Camps J, Mathews P, Barenboim-Stapleton L, Nguyen QT, Difilippantonio MJ, Ried T. Position of human chromosomes is conserved in mouse nuclei indicating a species-independent mechanism for maintaining genome organization. Chromosoma. 117: 499-509. PMID 18563425 DOI: 10.1007/s00412-008-0171-7  0.717
2008 Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, Chang HY, Bohr VA, Ried T, Gozani O, Chua KF. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature. 452: 492-6. PMID 18337721 DOI: 10.1038/Nature06736  0.327
2008 Camps J, Grade M, Nguyen QT, Hörmann P, Becker S, Hummon AB, Rodriguez V, Chandrasekharappa S, Chen Y, Difilippantonio MJ, Becker H, Ghadimi BM, Ried T. Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome. Cancer Research. 68: 1284-95. PMID 18316590 DOI: 10.1158/0008-5472.Can-07-2864  0.795
2008 Roblick UJ, Bader FG, Lenander C, Hellman U, Zimmermann K, Becker S, Ost A, Alaiya A, Bruch HP, Keller R, Mirow L, Franzén B, Ried T, Auer G, Habermann JK. Undifferentiated pelvic adenocarcinomas: diagnostic potential of protein profiling and multivariate analysis. International Journal of Colorectal Disease. 23: 483-91. PMID 18293003 DOI: 10.1007/S00384-008-0448-6  0.327
2008 Xu M, Yu Q, Subrahmanyam R, Difilippantonio MJ, Ried T, Sen JM. Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo. Molecular and Cellular Biology. 28: 1713-23. PMID 18160717 DOI: 10.1128/Mcb.01360-07  0.594
2008 Habermann JK, Bader FG, Franke C, Zimmermann K, Gemoll T, Fritzsche B, Ried T, Auer G, Bruch HP, Roblick UJ. From the genome to the proteome--biomarkers in colorectal cancer. Langenbeck's Archives of Surgery / Deutsche Gesellschaft FüR Chirurgie. 393: 93-104. PMID 17938952 DOI: 10.1007/S00423-007-0230-1  0.368
2008 Martin CL, Reshmi SC, Ried T, Gottberg W, Wilson JW, Reddy JK, Khanna P, Johnson JT, Myers EN, Gollin SM. Chromosomal imbalances in oral squamous cell carcinoma: Examination of 31 cell lines and review of the literature Oral Oncology. 44: 369-382. PMID 17681875 DOI: 10.1016/J.Oraloncology.2007.05.003  0.367
2008 Grade M, Hummon A, Camps J, Emons G, Spitzner M, Gaedcke J, Difilippantonio M, Ghadimi B, Caplen N, Ried T. 551 POSTER RNAi-based identification of potential targets in colorectal cancers European Journal of Cancer Supplements. 6: 174. DOI: 10.1016/S1359-6349(08)72485-6  0.722
2007 Dundr M, Ospina JK, Sung MH, John S, Upender M, Ried T, Hager GL, Matera AG. Actin-dependent intranuclear repositioning of an active gene locus in vivo. The Journal of Cell Biology. 179: 1095-103. PMID 18070915 DOI: 10.1083/Jcb.200710058  0.593
2007 Griffin CA, Morsberger L, Hawkins AL, Haddadin M, Patel A, Ried T, Schrock E, Perlman EJ, Jaffee E. Molecular cytogenetic characterization of pancreas cancer cell lines reveals high complexity chromosomal alterations. Cytogenetic and Genome Research. 118: 148-56. PMID 18000365 DOI: 10.1159/000108295  0.361
2007 Chen MJ, Dumitrache LC, Wangsa D, Ma SM, Padilla-Nash H, Ried T, Hasty P. Cisplatin depletes TREX2 and causes Robertsonian translocations as seen in TREX2 knockout cells. Cancer Research. 67: 9077-83. PMID 17909011 DOI: 10.1158/0008-5472.Can-07-1146  0.303
2007 Callén E, Jankovic M, Difilippantonio S, Daniel JA, Chen HT, Celeste A, Pellegrini M, McBride K, Wangsa D, Bredemeyer AL, Sleckman BP, Ried T, Nussenzweig M, Nussenzweig A. ATM Prevents the Persistence and Propagation of Chromosome Breaks in Lymphocytes Cell. 130: 63-75. PMID 17599403 DOI: 10.1016/J.Cell.2007.06.016  0.318
2007 Hummon AB, Lim SR, Difilippantonio MJ, Ried T. Isolation and solubilization of proteins after TRIzol extraction of RNA and DNA from patient material following prolonged storage. Biotechniques. 42: 467-70, 472. PMID 17489233 DOI: 10.2144/000112401  0.726
2007 Soutoglou E, Dorn JF, Sengupta K, Jasin M, Nussenzweig A, Ried T, Danuser G, Misteli T. Positional stability of single double-strand breaks in mammalian cells. Nature Cell Biology. 9: 675-82. PMID 17486118 DOI: 10.1038/Ncb1591  0.357
2007 Xiao C, Sharp JA, Kawahara M, Davalos AR, Difilippantonio MJ, Hu Y, Li W, Cao L, Buetow K, Ried T, Chadwick BP, Deng CX, Panning B. The XIST noncoding RNA functions independently of BRCA1 in X inactivation. Cell. 128: 977-89. PMID 17350580 DOI: 10.1016/J.Cell.2007.01.034  0.624
2007 Sengupta K, Upender MB, Barenboim-Stapleton L, Nguyen QT, Wincovitch SM, Garfield SH, Difilippantonio MJ, Ried T. Artificially introduced aneuploid chromosomes assume a conserved position in colon cancer cells. Plos One. 2: e199. PMID 17332847 DOI: 10.1371/journal.pone.0000199  0.723
2007 Duelli DM, Padilla-Nash HM, Berman D, Murphy KM, Ried T, Lazebnik Y. A virus causes cancer by inducing massive chromosomal instability through cell fusion. Current Biology : Cb. 17: 431-7. PMID 17320392 DOI: 10.1016/j.cub.2007.01.049  0.4
2007 Wang X, Liu L, Montagna C, Ried T, Deng CX. Haploinsufficiency of Parp1 accelerates Brca1-associated centrosome amplification, telomere shortening, genetic instability, apoptosis, and embryonic lethality Cell Death and Differentiation. 14: 924-931. PMID 17318223 DOI: 10.1038/sj.cdd.4402105  0.606
2007 Padilla-Nash HM, Wu K, Just H, Ried T, Thestrup-Pedersen K. Spectral karyotyping demonstrates genetically unstable skin-homing T lymphocytes in cutaneous T-cell lymphoma Experimental Dermatology. 16: 98-103. PMID 17222222 DOI: 10.1111/J.1600-0625.2006.00507.X  0.367
2007 Grade M, Hörmann P, Becker S, Hummon AB, Wangsa D, Varma S, Simon R, Liersch T, Becker H, Difilippantonio MJ, Ghadimi BM, Ried T. Gene expression profiling reveals a massive, aneuploidy-dependent transcriptional deregulation and distinct differences between lymph node-negative and lymph node-positive colon carcinomas. Cancer Research. 67: 41-56. PMID 17210682 DOI: 10.1158/0008-5472.Can-06-1514  0.764
2007 Habermann JK, Paulsen U, Roblick UJ, Upender MB, McShane LM, Korn EL, Wangsa D, Krüger S, Duchrow M, Bruch HP, Auer G, Ried T. Stage-specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesis. Genes, Chromosomes & Cancer. 46: 10-26. PMID 17044061 DOI: 10.1002/Gcc.20382  0.484
2006 Padilla-Nash HM, Barenboim-Stapleton L, Difilippantonio MJ, Ried T. Spectral karyotyping analysis of human and mouse chromosomes. Nature Protocols. 1: 3129-42. PMID 17406576 DOI: 10.1038/nprot.2006.358  0.683
2006 Helou K, Padilla-Nash H, Wangsa D, Karlsson E, Österberg L, Karlsson P, Ried T, Knutsen T. Comparative genome hybridization reveals specific genomic imbalances during the genesis from benign through borderline to malignant ovarian tumors Cancer Genetics and Cytogenetics. 170: 1-8. PMID 16965948 DOI: 10.1016/J.Cancergencyto.2006.04.010  0.429
2006 Andersson S, Wallin KL, Hellström AC, Morrison LE, Hjerpe A, Auer G, Ried T, Larsson C, Heselmeyer-Haddad K. Frequent gain of the human telomerase gene TERC at 3q26 in cervical adenocarcinomas. British Journal of Cancer. 95: 331-8. PMID 16847471 DOI: 10.1038/sj.bjc.6603253  0.335
2006 Jang W, Yonescu R, Knutsen T, Brown T, Reppert T, Sirotkin K, Schuler GD, Ried T, Kirsch IR. Linking the human cytogenetic map with nucleotide sequence: the CCAP clone set. Cancer Genetics and Cytogenetics. 168: 89-97. PMID 16843097 DOI: 10.1016/j.cancergencyto.2006.01.001  0.336
2006 Grade M, Becker H, Liersch T, Ried T, Ghadimi BM. Molecular cytogenetics: Genomic imbalances in colorectal cancer and their clinical impact Cellular Oncology. 28: 71-84. PMID 16823176 DOI: 10.1155/2006/173815  0.489
2006 Knutsen T, Vakulchuk A, Mosijczuk AD, Gabrea A, Ried T, Tretyak N. Complex rearrangements involving der(8)t(8;20) and der(14)t(8;14)t(11;14), CCND1, and duplication of IgH constant region in acute plasmablastic leukemia Cancer Genetics and Cytogenetics. 164: 137-141. PMID 16434317 DOI: 10.1016/J.Cancergencyto.2005.08.027  0.327
2006 Grade M, Ghadimi BM, Varma S, Simon R, Wangsa D, Barenboim-Stapleton L, Liersch T, Becker H, Ried T, Difilippantonio MJ. Aneuploidy-dependent massive deregulation of the cellular transcriptome and apparent divergence of the Wnt/beta-catenin signaling pathway in human rectal carcinomas. Cancer Research. 66: 267-82. PMID 16397240 DOI: 10.1158/0008-5472.Can-05-2533  0.74
2006 Focarelli ML, Montagna C, Colombo R, Ried T, Vezzoni P, Musio A. SMC1 inhibition results in FRA3B expression but has no effect on its delayed replication Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 595: 23-28. PMID 16242161 DOI: 10.1016/J.Mrfmmm.2005.09.002  0.598
2006 Grade M, Liersch T, Varma S, Difilippantonio MJ, Langer C, Simon R, Ried T, Becker H, Ghadimi BM. P67. Pretherapeutical gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy and its impact on disease free survival European Journal of Cancer Supplements. 4: 51-52. DOI: 10.1016/j.ejcsup.2006.04.127  0.603
2005 McNamara G, Difilippantonio MJ, Ried T. Microscopy and image analysis. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. Unit 4.4. PMID 18428379 DOI: 10.1002/0471142905.hg0404s46  0.575
2005 Han SS, Shaffer AL, Peng L, Chung ST, Lim JH, Maeng S, Kim JS, McNeil N, Ried T, Staudt LM, Janz S. Molecular and cytological features of the mouse B-cell lymphoma line iMycEmu-1. Molecular Cancer. 4: 40. PMID 16277667 DOI: 10.1186/1476-4598-4-40  0.403
2005 Chen KG, Wang YC, Schaner ME, Francisco B, Durán GE, Juric D, Huff LM, Padilla-Nash H, Ried T, Fojo T, Sikic BI. Genetic and epigenetic modeling of the origins of multidrug-resistant cells in a human sarcoma cell line. Cancer Research. 65: 9388-97. PMID 16230402 DOI: 10.1158/0008-5472.Can-04-4133  0.509
2005 Bowen TJ, Yakushiji H, Montagna C, Jain S, Ried T, Wynshaw-Boris A. Atm heterozygosity cooperates with loss of Brca1 to increase the severity of mammary gland cancer and reduce ductal branching. Cancer Research. 65: 8736-46. PMID 16204043 DOI: 10.1158/0008-5472.Can-05-1598  0.603
2005 Desper R, Difilippantonio MJ, Ried T, Schäffer AA. A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis Mathematical Biosciences. 197: 67-87. PMID 16043196 DOI: 10.1016/j.mbs.2005.05.005  0.682
2005 Rao VK, Wangsa D, Robey RW, Huff L, Honjo Y, Hung J, Knutsen T, Ried T, Bates SE. Characterization of ABCG2 gene amplification manifesting as extrachromosomal DNA in mitoxantrone-selected SF295 human glioblastoma cells Cancer Genetics and Cytogenetics. 160: 126-133. PMID 15993268 DOI: 10.1016/j.cancergencyto.2004.12.013  0.401
2005 Knutsen T, Gobu V, Knaus R, Padilla-Nash H, Augustus M, Strausberg RL, Kirsch IR, Sirotkin K, Ried T. The interactive online SKY/M-FISH & CGH database and the Entrez Cancer Chromosomes search database: Linkage of chromosomal aberrations with the genome sequence Genes Chromosomes and Cancer. 44: 52-64. PMID 15934046 DOI: 10.1002/gcc.20224  0.384
2005 Rao VK, Knutsen T, Ried T, Wangsa D, Flynn BM, Langham G, Egorin MJ, Cole D, Balis F, Steinberg SM, Bates S, Fojo T. The extent of chromosomal aberrations induced by chemotherapy in non-human primates depends on the schedule of administration. Mutation Research. 583: 105-19. PMID 15927870 DOI: 10.1016/J.Mrgentox.2005.01.013  0.368
2005 Ghadimi BM, Grade M, Difilippantonio MJ, Varma S, Simon R, Montagna C, Füzesi L, Langer C, Becker H, Liersch T, Ried T. Effectiveness of gene expression profiling for response prediction of rectal adenocarcinomas to preoperative chemoradiotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 1826-38. PMID 15774776 DOI: 10.1200/JCO.2005.00.406  0.735
2005 Sung SP, Joong SK, Tessarollo L, Owens JD, Peng L, Seong SH, Seung TC, Torrey TA, Cheung WC, Polakiewicz RD, McNeil N, Ried T, Mushinski JF, Morse HC, Janz S. Insertion of c-Myc into Igh induces B-cell and plasma-cell neoplasms in mice Cancer Research. 65: 1306-1315. PMID 15735016 DOI: 10.1158/0008-5472.Can-04-0268  0.374
2005 Barenboim-Stapleton L, Yang X, Tsokos M, Wigginton JM, Padilla-Nash H, Ried T, Thiele CJ. Pediatric pancreatoblastoma: Histopathologic and cytogenetic characterization of tumor and derived cell line Cancer Genetics and Cytogenetics. 157: 109-117. PMID 15721631 DOI: 10.1016/j.cancergencyto.2004.05.017  0.38
2005 Stoltzfus P, Heselmeyer-Haddad K, Castro J, White N, Silfverswärd C, Sjövall K, Einhorn N, Tryggvason K, Auer G, Ried T, Nordström B. Gain of chromosome 3q is an early and consistent genetic aberration in carcinomas of the vulva. International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society. 15: 120-6. PMID 15670306 DOI: 10.1111/J.1048-891X.2005.15012.X  0.432
2005 Musio A, Montagna C, Mariani T, Tilenni M, Focarelli ML, Brait L, Indino E, Benedetti PA, Chessa L, Albertini A, Ried T, Vezzoni P. SMC1 involvement in fragile site expression. Human Molecular Genetics. 14: 525-33. PMID 15640246 DOI: 10.1093/hmg/ddi049  0.57
2005 Ghadimi B, Grade M, Liersch T, Ried T, Becker H. Gene expression profiling predicts response of rectal adenocarcinomas to neoadjuvant radiochemotherapy Zeitschrift FüR Gastroenterologie. 43. DOI: 10.1055/S-2005-920368  0.303
2004 Ried T, Dorritie K, Weaver Z, Wangsa D, Difilippantonio MJ, Montagna C. Molecular cytogenetics of mouse models of breast cancer. Breast Disease. 19: 59-67. PMID 15687698 DOI: 10.3233/Bd-2004-19108  0.732
2004 Upender MB, Habermann JK, McShane LM, Korn EL, Barrett JC, Difilippantonio MJ, Ried T. Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells Cancer Research. 64: 6941-6949. PMID 15466185 DOI: 10.1158/0008-5472.Can-04-0474  0.769
2004 Lucas PJ, McNeil N, Hilgenfeld E, Choudhury B, Kim SJ, Eckhaus MA, Ried T, Gress RE. Transforming growth factor-β pathway serves as a primary tumor suppressor in CD8+ T cell tumorigenesis Cancer Research. 64: 6524-6529. PMID 15374963 DOI: 10.1158/0008-5472.Can-04-0896  0.385
2004 Dorritie K, Montagna C, Difilippantonio MJ, Ried T. Advanced molecular cytogenetics in human and mouse Expert Review of Molecular Diagnostics. 4: 663-676. PMID 15347260 DOI: 10.1586/14737159.4.5.663  0.782
2004 Roblick UJ, Hirschberg D, Habermann JK, Palmberg C, Becker S, Krüger S, Gustafsson M, Bruch HP, Franzén B, Ried T, Bergmann T, Auer G, Jörnvall H. Sequential proteome alterations during genesis and progression of colon cancer. Cellular and Molecular Life Sciences : Cmls. 61: 1246-55. PMID 15141310 DOI: 10.1007/S00018-004-4049-4  0.362
2004 Musio A, Mariani T, Montagna C, Zambroni D, Ascoli C, Ried T, Vezzoni P. Recapitulation of the Roberts syndrome cellular phenotype by inhibition of INCENP, ZWINT-1 and ZW10 genes Gene. 331: 33-40. PMID 15094189 DOI: 10.1016/J.Gene.2004.01.028  0.681
2004 Guda K, Upender MB, Belinsky G, Flynn C, Nakanishi M, Marino JN, Ried T, Rosenberg DW. Carcinogen-induced colon tumors in mice are chromosomally stable and are characterized by low-level microsatellite instability. Oncogene. 23: 3813-21. PMID 15021908 DOI: 10.1038/Sj.Onc.1207489  0.467
2004 Janicki SM, Tsukamoto T, Salghetti SE, Tansey WP, Sachidanandam R, Prasanth KV, Ried T, Shav-Tal Y, Bertrand E, Singer RH, Spector DL. From silencing to gene expression: real-time analysis in single cells. Cell. 116: 683-98. PMID 15006351 DOI: 10.1016/S0092-8674(04)00171-0  0.369
2004 Pack SD, Alper OM, Stromberg K, Augustus M, Ozdemirli M, Miermont AM, Klus G, Rusin M, Slack R, Hacker NF, Ried T, Szallasi Z, Alper O. Simultaneous suppression of epidermal growth factor receptor and c-erbB-2 reverses aneuploidy and malignant phenotype of a human ovarian carcinoma cell line. Cancer Research. 64: 789-94. PMID 14871800 DOI: 10.1158/0008-5472.Can-03-1982  0.386
2004 Schaeffer AJ, Nguyen M, Liem A, Lee D, Montagna C, Lambert PF, Ried T, Difilippantonio MJ. E6 and E7 Oncoproteins Induce Distinct Patterns of Chromosomal Aneuploidy in Skin Tumors from Transgenic Mice Cancer Research. 64: 538-546. PMID 14744767 DOI: 10.1158/0008-5472.Can-03-0124  0.82
2004 Huang AM, Montagna C, Sharan S, Ni Y, Ried T, Sterneck E. Loss of CCAAT/enhancer binding protein δ promotes chromosomal instability Oncogene. 23: 1549-1557. PMID 14716301 DOI: 10.1038/Sj.Onc.1207285  0.644
2004 Habermann JK, Hellman K, Freitag S, Heselmeyer-Haddad K, Hellström AC, Shah K, Auer G, Ried T. A recurrent gain of chromosome arm 3q in primary squamous carcinoma of the vagina. Cancer Genetics and Cytogenetics. 148: 7-13. PMID 14697635 DOI: 10.1016/S0165-4608(03)00245-0  0.481
2004 Ried T, Mahler V, Vogt P, Blonden L, van Ommen GJB, Cremer T, Cremer M. Direct carrier detection by in situ suppression hybridization with cosmid clones of the Duchenne/Becker muscular dystrophy locus Human Genetics. 85: 581-586. PMID 2227948 DOI: 10.1007/Bf00193578  0.42
2004 Dierov J, Padilla-Nash H, Ried T, Carroll M. BCR/ABL Expression Increases the Formation of Chromosomal Translocations after DNA Damage. Blood. 104: 713-713. DOI: 10.1182/Blood.V104.11.713.713  0.47
2004 Ried T, Dorritie K, Weaver Z, Wangsa D, Difilippantonio MJ, Montagna C. Molecular cytogenetics of mouse models of breast cancer Breast Disease. 19: 59-67.  0.716
2003 Tchinda J, Volpert S, McNeil N, Neumann T, Kennerknecht I, Ried T, Büchner T, Serve H, Berdel WE, Horst J, Hilgenfeld E. Multicolor karyotyping in acute myeloid leukemia. Leukemia & Lymphoma. 44: 1843-53. PMID 14738135 DOI: 10.1080/10428190310001603605  0.306
2003 Whitmarsh RJ, Saginario C, Zhuo Y, Hilgenfeld E, Rappaport EF, Megonigal MD, Carroll M, Liu M, Osheroff N, Cheung NKV, Slater DJ, Ried T, Knutsen T, Blair IA, Felix CA. Reciprocal DNA topoisomerase II cleavage events at 5′-TATTA-3′ sequences in MLL and AF-9 create homologous single-stranded overhangs that anneal to form der(11) and der(9) genomic breakpoint junctions in treatment-related AML without further processing Oncogene. 22: 8448-8459. PMID 14627986 DOI: 10.1038/Sj.Onc.1207052  0.313
2003 Srivastava M, Montagna C, Leighton X, Glasman M, Naga S, Eidelman O, Ried T, Pollard HB. Haploinsufficiency of Anx7 tumor suppressor gene and consequent genomic instability promotes tumorigenesis in the Anx7(+/-) mouse Proceedings of the National Academy of Sciences of the United States of America. 100: 14287-14292. PMID 14608035 DOI: 10.1073/Pnas.2235927100  0.668
2003 Habermann JK, Upender MB, Roblick UJ, Krüger S, Freitag S, Blegen H, Bruch HP, Schimmelpenning H, Auer G, Ried T. Pronounced chromosomal instability and multiple gene amplifications characterize ulcerative colitis-associated colorectal carcinomas. Cancer Genetics and Cytogenetics. 147: 9-17. PMID 14580765 DOI: 10.1016/S0165-4608(03)00219-X  0.348
2003 Heselmeyer-Haddad K, Janz V, Castle PE, Chaudhri N, White N, Wilber K, Morrison LE, Auer G, Burroughs FH, Sherman ME, Ried T. Detection of genomic amplification of the human telomerase gene (TERC) in cytologic specimens as a genetic test for the diagnosis of cervical dysplasia. The American Journal of Pathology. 163: 1405-16. PMID 14507648 DOI: 10.1016/S0002-9440(10)63498-0  0.318
2003 Crabtree JS, Scacheri PC, Ward JM, McNally SR, Swain GP, Montagna C, Hager JH, Hanahan D, Edlund H, Magnuson MA, Garrett-Beal L, Burns AL, Ried T, Chandrasekharappa SC, Marx SJ, et al. Of mice and MEN1: Insulinomas in a conditional mouse knockout. Molecular and Cellular Biology. 23: 6075-85. PMID 12917331 DOI: 10.1128/Mcb.23.17.6075-6085.2003  0.616
2003 Celeste A, Difilippantonio S, Difilippantonio MJ, Fernandez-Capetillo O, Pilch DR, Sedelnikova OA, Eckhaus M, Ried T, Bonner WM, Nussenzweig A. H2AX haploinsufficiency modifies genomic stability and tumor susceptibility Cell. 114: 371-383. PMID 12914701 DOI: 10.1016/S0092-8674(03)00567-1  0.662
2003 Forgues M, Difilippantonio MJ, Linke SP, Ried T, Nagashima K, Feden J, Valerie K, Fukasawa K, Wang XW. Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles. Molecular and Cellular Biology. 23: 5282-92. PMID 12861014 DOI: 10.1128/Mcb.23.15.5282-5292.2003  0.781
2003 Musio A, Montagna C, Zambroni D, Indino E, Barbieri O, Citti L, Villa A, Ried T, Vezzoni P. Inhibition of BUB1 results in genomic instability and anchorage-independent growth of normal human fibroblasts Cancer Research. 63: 2855-2863. PMID 12782591  0.645
2003 Blegen H, Will JS, Ghadimi BM, Nash HP, Zetterberg A, Auer G, Ried T. DNA amplifications and aneuploidy, high proliferative activity and impaired cell cycle control characterize breast carcinomas with poor prognosis. Analytical Cellular Pathology : the Journal of the European Society For Analytical Cellular Pathology. 25: 103-14. PMID 12775914 DOI: 10.1155/2003/491362  0.467
2003 Knutsen T, Pack S, Petropavlovskaja M, Padilla-Nash H, Knight C, Mickley LA, Ried T, Elwood PC, Roberts SJ. Cytogenetic, spectral karyotyping, fluorescence in situ hybridization, and comparative genomic hybridization characterization of two new secondary leukemia cell lines with 5q deletions, and MYC and MLL amplification. Genes, Chromosomes & Cancer. 37: 270-81. PMID 12759925 DOI: 10.1002/gcc.10200  0.317
2003 Pavlovich CP, Padilla-Nash H, Wangsa D, Nickerson ML, Matrosova V, Linehan WM, Ried T, Phillips JL. Patterns of aneuploidy in stage IV clear cell renal cell carcinoma revealed by comparative genomic hybridization and spectral karyotyping. Genes, Chromosomes & Cancer. 37: 252-60. PMID 12759923 DOI: 10.1002/Gcc.10209  0.376
2003 Montagna C, Lyu MS, Hunter K, Lukes L, Lowther W, Reppert T, Hissong B, Weaver Z, Ried T. The Septin 9 (MSF) gene is amplified and overexpressed in mouse mammary gland adenocarcinomas and human breast cancer cell lines. Cancer Research. 63: 2179-87. PMID 12727837  0.674
2002 Rockwood LD, Torrey TA, Kim JS, Coleman AE, Kovalchuk AL, Xiang S, Ried T, Morse HC, Janz S. Genomic instability in mouse Burkitt lymphoma is dominated by illegitimate genetic recombinations, not point mutations Oncogene. 21: 7235-7240. PMID 12370814 DOI: 10.1038/Sj.Onc.1205697  0.38
2002 Difilippantonio MJ, Petersen S, Chen HT, Johnson R, Jasin M, Kanaar R, Ried T, Nussenzweig A. Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification Journal of Experimental Medicine. 196: 469-480. PMID 12186839 DOI: 10.1084/Jem.20020851  0.679
2002 Weaver Z, Montagna C, Xu X, Howard T, Gadina M, Brodie SG, Deng CX, Ried T. Mammary tumors in mice conditionally mutant for Brca1 exhibit gross genomic instability and centrosome amplification yet display a recurring distribution of genomic imbalances that is similar to human breast cancer Oncogene. 21: 5097-5107. PMID 12140760 DOI: 10.1038/Sj.Onc.1205636  0.708
2002 Slater DJ, Hilgenfeld E, Rappaport EF, Shah N, Meek RG, Williams WR, Lovett BD, Osheroff N, Autar RS, Ried T, Felix CA. MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomerase II cleavage site. Oncogene. 21: 4706-14. PMID 12096348 DOI: 10.1038/Sj.Onc.1205572  0.422
2002 Heselmeyer-Haddad K, Chaudhri N, Stoltzfus P, Cheng JC, Wilber K, Morrison L, Auer G, Ried T. Detection of chromosomal aneuploidies and gene copy number changes in fine needle aspirates is a specific, sensitive, and objective genetic test for the diagnosis of breast cancer. Cancer Research. 62: 2365-9. PMID 11956098  0.383
2002 Hilgenfeld E, Montagna C, Padilla-Nash H, Stapleton L, Heselmeyer-Haddad K, Ried T. Spectral karyotyping in cancer cytogenetics. Methods in Molecular Medicine. 68: 29-44. PMID 11901510 DOI: 10.1385/1-59259-135-3:029  0.587
2002 Platzer P, Upender MB, Wilson K, Willis J, Lutterbaugh J, Nosrati A, Willson JK, Mack D, Ried T, Markowitz S. Silence of chromosomal amplifications in colon cancer. Cancer Research. 62: 1134-8. PMID 11861394  0.44
2002 Montagna C, Andrechek ER, Padilla-Nash H, Muller WJ, Ried T. Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu. Oncogene. 21: 890-8. PMID 11840334 DOI: 10.1038/sj.onc.1205146  0.686
2002 Staebler A, Heselmeyer-Haddad K, Bell K, Riopel M, Perlman E, Ried T, Kurman RJ. Micropapillary serous carcinoma of the ovary has distinct patterns of chromosomal imbalances by comparative genomic hybridization compared with atypical proliferative serous tumors and serous carcinomas. Human Pathology. 33: 47-59. PMID 11823973 DOI: 10.1053/hupa.2002.30212  0.31
2001 Petersen S, Casellas R, Reina-San-Martin B, Chen HT, Difilippantonio MJ, Wilson PC, Hanitsch L, Celeste A, Muramatsu M, Pilch DR, Redon C, Ried T, Bonner WM, Honjo T, Nussenzweig MC, et al. AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching Nature. 414: 660-665. PMID 11740565 DOI: 10.1038/414660A  0.619
2001 Blegen H, Michael Ghadimi B, Jauho A, Zetterberg A, Eriksson E, Auer G, Ried T. Genetic instability promotes the acquisition of chromosomal imbalances in T1b and T1c breast adenocarcinomas Analytical Cellular Pathology. 22: 123-131. PMID 11455031 DOI: 10.1155/2001/126030  0.337
2001 Hilgenfeld E, Padilla-Nash H, McNeil N, Knutsen T, Montagna C, Tchinda J, Horst J, Ludwig WD, Serve H, Büchner T, Berdel WE, Schröck E, Ried T. Spectral karyotyping and fluorescence in situ hybridization detect novel chromosomal aberrations, a recurring involvement of chromosome 21 and amplification of the MYC oncogene in acute myeloid leukaemia M2. British Journal of Haematology. 113: 305-17. PMID 11380393 DOI: 10.1046/J.1365-2141.2001.02723.X  0.449
2001 Phillips JL, Ghadimi BM, Wangsa D, Padilla-Nash H, Worrell R, Hewitt S, Walther M, Linehan WM, Klausner RD, Ried T. Molecular cytogenetic characterization of early and late renal cell carcinomas in von Hippel-Lindau disease. Genes, Chromosomes & Cancer. 31: 1-9. PMID 11284029 DOI: 10.1002/Gcc.1111  0.366
2001 Padilla-Nash HM, Heselmeyer-Haddad K, Wangsa D, Zhang H, Ghadimi BM, Macville M, Augustus M, Schröck E, Hilgenfeld E, Ried T. Jumping translocations are common in solid tumor cell lines and result in recurrent fusions of whole chromosome arms. Genes, Chromosomes & Cancer. 30: 349-63. PMID 11241788 DOI: 10.1002/gcc.1101  0.374
2001 Allen DM, van Praag H, Ray J, Weaver Z, Winrow CJ, Carter TA, Braquet R, Harrington E, Ried T, Brown KD, Gage FH, Barlow C. Ataxia telangiectasia mutated is essential during adult neurogenesis. Genes & Development. 15: 554-66. PMID 11238376 DOI: 10.1101/Gad.869001  0.306
2001 Kirsch IR, Ried T. Integration of cytogenetic data with genome maps and available probes: present status and future promise. Seminars in Hematology. 37: 420-8. PMID 11071363 DOI: 10.1016/S0037-1963(00)90021-0  0.346
2001 Kirsch I, Yonescu R, Brown T, Reppert T, Knutsen T, Sirotkin K, Ried T. The Cancer Chromosome Aberration Project: Update on BAC clone repository and database Nature Genetics. 27: 64-65. DOI: 10.1038/87154  0.327
2001 Ghadimi B, Uhr J, Tucker T, Heselmeyer-Haddad K, Ried T, Becker H. Interphase cytogenetics with DNA-probes for chromosome 8 to detect circulating tumor cells in breast cancer patients European Journal of Cancer. 37: S166. DOI: 10.1016/S0959-8049(01)81097-2  0.353
2000 McNeil N, Ried T. Novel molecular cytogenetic techniques for identifying complex chromosomal rearrangements: technology and applications in molecular medicine. Expert Reviews in Molecular Medicine. 2000: 1-14. PMID 14585138 DOI: 10.1017/S1462399400001940  0.369
2000 Chen HT, Bhandoola A, Difilippantonio MJ, Zhu J, Brown MJ, Tai X, Rogakou EP, Brotz TM, Bonner WM, Ried T, Nussenzweig A. Response to RAG-mediated VDJ cleavage by NBS1 and gamma-H2AX. Science (New York, N.Y.). 290: 1962-5. PMID 11110662 DOI: 10.1126/Science.290.5498.1962  0.623
2000 Coleman AE, Ried T, Janz S. Chromosomes 1 and 5 harbor plasmacytoma progressor genes in mice. Genes, Chromosomes & Cancer. 29: 70-4. PMID 10918396 DOI: 10.1002/1098-2264(2000)9999:9999<::Aid-Gcc1009>3.0.Co;2-C  0.43
2000 Difilippantonio MJ, Zhu J, Chen HT, Meffre E, Nussenzweig MC, Max EE, Ried T, Nussenzweig A. DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation. Nature. 404: 510-4. PMID 10761921 DOI: 10.1038/35006670  0.732
2000 Kirsch IR, Green ED, Yonescu R, Strausberg R, Carter N, Bentley D, Leversha MA, Dunham I, Braden VV, Hilgenfeld E, Schuler G, Lash AE, Shen GL, Martelli M, Kuehl WM, ... ... Ried T, et al. A systematic, high-resolution linkage of the cytogenetic and physical maps of the human genome. Nature Genetics. 24: 339-40. PMID 10742091 DOI: 10.1038/74149  0.308
2000 Hu N, Roth MJ, Polymeropolous M, Tang ZZ, Emmert-Buck MR, Wang QH, Goldstein AM, Feng SS, Dawsey SM, Ding T, Zhuang ZP, Han XY, Ried T, Giffen C, Taylor PR. Identification of novel regions of allelic loss from a genomewide scan of esophageal squamous-cell carcinoma in a high-risk Chinese population. Genes, Chromosomes & Cancer. 27: 217-28. PMID 10679910 DOI: 10.1002/(Sici)1098-2264(200003)27:3<217::Aid-Gcc1>3.0.Co;2-A  0.437
2000 Ghadimi BM, Heselmeyer-Haddad K, Auer G, Ried T. Interphase cytogenetics: at the interface of genetics and morphology. Analytical Cellular Pathology : the Journal of the European Society For Analytical Cellular Pathology. 19: 3-6. PMID 10661620 DOI: 10.1155/1999/458729  0.47
2000 Ghadimi BM, Sackett DL, Difilippantonio MJ, Schröck E, Neumann T, Jauho A, Auer G, Ried T. Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations Genes Chromosomes and Cancer. 27: 183-190. PMID 10612807 DOI: 10.1002/(SICI)1098-2264(200002)27:2<183::AID-GCC10>3.0.CO;2-P  0.813
2000 Knutsen T, Rao VK, Ried T, Mickley L, Schneider E, Miyake K, Ghadimi BM, Padilla-Nash H, Pack S, Greenberger L, Cowan K, Dean M, Fojo T, Bates S. Amplification of 4q21-q22 and the MXR gene in independently derived mitoxantrone-resistant cell lines. Genes, Chromosomes & Cancer. 27: 110-6. PMID 10564593 DOI: 10.1002/(Sici)1098-2264(200001)27:1<110::Aid-Gcc14>3.0.Co;2-4  0.35
2000 Liyanage M, Weaver Z, Barlow C, Coleman A, Pankratz DG, Anderson S, Wynshaw-Boris A, Ried T. Abnormal rearrangement within the α/δ T-cell receptor locus in lymphomas from Atm-deficient mice Blood. 96: 1940-1946. DOI: 10.1182/Blood.V96.5.1940.H8001940_1940_1946  0.355
2000 Blegen H, Einhorn N, Sjövall K, Roschke A, Ghadimi BM, Mcshane LM, Nilsson B, Shah K, Ried T, Auer G. Prognostic significance of cell cycle proteins and genomic instability in borderline, early and advanced stage ovarian carcinomas International Journal of Gynecological Cancer. 10: 477-487. DOI: 10.1046/J.1525-1438.2000.00077.X  0.452
1999 Peschka B, Leygraaf J, Hansmann D, Hansmann M, Schröck E, Ried T, Engels H, Schwanitz G, Schubert R. Analysis of a de novo complex chromosome rearrangement involving chromosomes 4, 11, 12 and 13 and eight breakpoints by conventional cytogenetic, fluorescence in situ hybridization and spectral karyotyping. Prenatal Diagnosis. 19: 1143-9. PMID 10590433 DOI: 10.1002/(SICI)1097-0223(199912)19:12<1143::AID-PD730>3.0.CO;2-9  0.314
1999 Simbulan-Rosenthal CM, Haddad BR, Rosenthal DS, Weaver Z, Coleman A, Luo R, Young HM, Wang ZQ, Ried T, Smulson ME. Chromosomal aberrations in PARP(-/-) mice: genome stabilization in immortalized cells by reintroduction of poly(ADP-ribose) polymerase cDNA. Proceedings of the National Academy of Sciences of the United States of America. 96: 13191-6. PMID 10557296 DOI: 10.1073/Pnas.96.23.13191  0.478
1999 Schriml LM, Padilla-Nash HM, Coleman A, Moen P, Nash WG, Menninger J, Jones G, Ried T, Dean M. Tyramide signal amplification (TSA)-FISH applied to mapping PCR-labeled probes less than 1 kb in size Biotechniques. 27: 608-613. PMID 10489619 DOI: 10.2144/99273Pf01  0.405
1999 Liang JC, Ning Y, Wang RY, Padilla-Nash HM, Schröck E, Soenksen D, Nagarajan L, Ried T. Spectral karyotypic study of the HL-60 cell line: detection of complex rearrangements involving chromosomes 5, 7, and 16 and delineation of critical region of deletion on 5q31.1. Cancer Genetics and Cytogenetics. 113: 105-9. PMID 10484974 DOI: 10.1016/S0165-4608(99)00030-8  0.336
1999 Coleman AE, Ried T, Janz S. Recurrent non-reciprocal translocations of chromosome 5 in primary T(12;15)-positive BALB/c plasmacytomas. Current Topics in Microbiology and Immunology. 246: 175-80; discussion 1. PMID 10396054 DOI: 10.1007/978-3-642-60162-0_22  0.457
1999 Hilgenfeld E, Padilla-Nash H, Schröck E, Ried T. Analysis of B-cell neoplasias by spectral karyotyping (SKY). Current Topics in Microbiology and Immunology. 246: 169-74. PMID 10396053 DOI: 10.1007/978-3-642-60162-0_21  0.362
1999 Weaver ZA, McCormack SJ, Liyanage M, du Manoir S, Coleman A, Schröck E, Dickson RB, Ried T. A recurring pattern of chromosomal aberrations in mammary gland tumors of MMTV-cmyc transgenic mice. Genes, Chromosomes & Cancer. 25: 251-60. PMID 10379871 DOI: 10.1002/(Sici)1098-2264(199907)25:3<251::Aid-Gcc7>3.0.Co;2-3  0.404
1999 Ried T, Heselmeyer-Haddad K, Blegen H, Schröck E, Auer G. Genomic changes defining the genesis, progression, and malignancy potential in solid human tumors: a phenotype/genotype correlation. Genes, Chromosomes & Cancer. 25: 195-204. PMID 10379865 DOI: 10.1002/(SICI)1098-2264(199907)25:3<195::AID-GCC1>3.0.CO;2-8  0.387
1999 Ning Y, Laundon CH, Schröck E, Buchanan P, Ried T. Prenatal diagnosis of a mosaic extra structurally abnormal chromosome by spectral karyotyping. Prenatal Diagnosis. 19: 480-2. PMID 10360520 DOI: 10.1002/(Sici)1097-0223(199905)19:5<480::Aid-Pd547>3.0.Co;2-H  0.324
1999 Padilla-Nash HM, Nash WG, Padilla GM, Roberson KM, Robertson CN, Macville M, Schröck E, Ried T. Molecular cytogenetic analysis of the bladder carcinoma cell line BK-10 by spectral karyotyping. Genes, Chromosomes & Cancer. 25: 53-9. PMID 10221340 DOI: 10.1002/(SICI)1098-2264(199905)25:1<53::AID-GCC8>3.0.CO;2-T  0.403
1999 Xu X, Weaver Z, Linke SP, Li C, Gotay J, Wang XW, Harris CC, Ried T, Deng CX. Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells. Molecular Cell. 3: 389-95. PMID 10198641 DOI: 10.1016/S1097-2765(00)80466-9  0.32
1999 Ghadimi BM, Schröck E, Walker RL, Wangsa D, Jauho A, Meltzer PS, Ried T. Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas American Journal of Pathology. 154: 525-536. PMID 10027410 DOI: 10.1016/S0002-9440(10)65298-4  0.409
1999 Haddad BR, Schröck E, Meck J, Cowan J, Young H, Ferguson-Smith MA, du Manoir S, Ried T. Identification of de novo chromosomal markers and derivatives by spectral karyotyping. Human Genetics. 103: 619-25. PMID 9860306 DOI: 10.1007/S004390050878  0.453
1998 Huang B, Ning Y, Lamb AN, Sandlin CJ, Jamehdor M, Ried T, Bartley J. Identification of an unusual marker chromosome by spectral karyotyping. American Journal of Medical Genetics. 80: 368-72. PMID 9856565 DOI: 10.1002/(Sici)1096-8628(19981204)80:4<368::Aid-Ajmg12>3.0.Co;2-B  0.329
1998 Phelan MC, Blackburn W, Rogers RC, Crawford EC, Cooley NR, Schrock E, Ning Y, Ried T. FISH analysis of a complex chromosome rearrangement involving nine breakpoints on chromosomes 6, 12, 14 and 16. Prenatal Diagnosis. 18: 1174-80. PMID 9854728 DOI: 10.1002/(Sici)1097-0223(199811)18:11<1174::Aid-Pd411>3.0.Co;2-H  0.436
1998 Agarwal SK, Schröck E, Kester MB, Lee Burns A, Heffess CS, Ried T, Marx SJ. Comparative genomic hybridization analysis of human parathyroid tumors Cancer Genetics and Cytogenetics. 106: 30-36. PMID 9772906 DOI: 10.1016/S0165-4608(98)00049-1  0.459
1998 Ried T, Schröck E, Ning Y, Wienberg J. Chromosome painting: a useful art. Human Molecular Genetics. 7: 1619-26. PMID 9735383 DOI: 10.1093/Hmg/7.10.1619  0.348
1998 Knutsen T, Mickley LA, Ried T, Green ED, du Manoir S, Schröck E, Macville M, Ning Y, Robey R, Polymeropoulos M, Torres R, Fojo T. Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene, MDR1/P-glycoprotein, in drug-selected cell lines and patients with drug refractory ALL. Genes, Chromosomes & Cancer. 23: 44-54. PMID 9713996 DOI: 10.1002/(Sici)1098-2264(199809)23:1<44::Aid-Gcc7>3.0.Co;2-6  0.468
1998 Allen RJ, Smith SD, Moldwin RL, Lu MM, Giordano L, Vignon C, Suto Y, Harden A, Tomek R, Veldman T, Ried T, Larson RA, Le Beau MM, Rowley JD, Zeleznik-Le N. Establishment and characterization of a megakaryoblast cell line with amplification of MLL. Leukemia. 12: 1119-27. PMID 9665199 DOI: 10.1038/Sj.Leu.2401002  0.338
1998 McCormack SJ, Weaver Z, Deming S, Natarajan G, Torri J, Johnson MD, Liyanage M, Ried T, Dickson RB. Myc/p53 interactions in transgenic mouse mammary development, tumorigenesis and chromosomal instability. Oncogene. 16: 2755-66. PMID 9652742 DOI: 10.1038/Sj.Onc.1201804  0.3
1998 Blaschke RJ, Monaghan AP, Schiller S, Schechinger B, Rao E, Padilla-Nash H, Ried T, Rappold GA. SHOT, a SHOX-related homeobox gene, is implicated in craniofacial, brain, heart, and limb development. Proceedings of the National Academy of Sciences of the United States of America. 95: 2406-11. PMID 9482898 DOI: 10.1073/Pnas.95.5.2406  0.446
1998 Schröck E, Veldman T, Padilla-Nash H, Ning Y, Spurbeck J, Jalal S, Shaffer LG, Papenhausen P, Kozma C, Phelan MC, Kjeldsen E, Schonberg SA, O'Brien P, Biesecker L, du Manoir S, ... Ried T, et al. Spectral karyotyping refines cytogenetic diagnostics of constitutional chromosomal abnormalities. Human Genetics. 101: 255-62. PMID 9439652 DOI: 10.1007/S004390050626  0.336
1998 Ried T, Liyanage M, du Manoir S, Heselmeyer K, Auer G, Macville M, Schröck E. Tumor cytogenetics revisited: comparative genomic hybridization and spectral karyotyping. Journal of Molecular Medicine (Berlin, Germany). 75: 801-14. PMID 9428610 DOI: 10.1007/s001090050169  0.398
1998 Macville M, Veldman T, Padilla-Nash H, Wangsa D, O'Brien P, Schröck E, Ried T. Spectral karyotyping, a 24-colour FISH technique for the identification of chromosomal rearrangements. Histochemistry and Cell Biology. 108: 299-305. PMID 9387921 DOI: 10.1007/s004180050169  0.306
1998 Rao PH, Cigudosa JC, Ning Y, Calasanz MJ, Iida S, Tagawa S, Michaeli J, Klein B, Dalla-Favera R, Jhanwar SC, Ried T, Chaganti RSK. Multicolor Spectral Karyotyping Identifies New Recurring Breakpoints and Translocations in Multiple Myeloma Blood. 92: 1743-1748. DOI: 10.1182/Blood.V92.5.1743  0.447
1998 Chesi M, Bergsagel PL, Shonukan OO, Martelli ML, Brents LA, Chen T, Schröck E, Ried T, Kuehl WM. Frequent Dysregulation of the c-maf Proto-Oncogene at 16q23 by Translocation to an Ig Locus in Multiple Myeloma Blood. 91: 4457-4463. DOI: 10.1182/Blood.V91.12.4457  0.396
1998 Heselmeyer K, Hellström A, Blegen H, Schröck E, Silfverswärd C, Shah K, Auer G, Ried T. Primary Carcinoma of the Fallopian Tube International Journal of Gynecological Pathology. 17: 245-254. DOI: 10.1097/00004347-199807000-00009  0.303
1997 Heselmeyer K, du Manoir S, Blegen H, Friberg B, Svensson C, Schröck E, Veldman T, Shah K, Auer G, Ried T. A recurrent pattern of chromosomal aberrations and immunophenotypic appearance defines anal squamous cell carcinomas. British Journal of Cancer. 76: 1271-8. PMID 9374370 DOI: 10.1038/Bjc.1997.547  0.334
1997 Packenham JP, du Manoir S, Schrock E, Risinger JI, Dixon D, Denz DN, Evans JA, Berchuck A, Barrett JC, Devereux TR, Ried T. Analysis of genetic alterations in uterine leiomyomas and leiomyosarcomas by comparative genomic hybridization. Molecular Carcinogenesis. 19: 273-9. PMID 9290705 DOI: 10.1002/(Sici)1098-2744(199708)19:4<273::Aid-Mc9>3.0.Co;2-D  0.335
1997 Heselmeyer K, Macville M, Schröck E, Blegen H, Hellström AC, Shah K, Auer G, Ried T. Advanced-stage cervical carcinomas are defined by a recurrent pattern of chromosomal aberrations revealing high genetic instability and a consistent gain of chromosome arm 3q. Genes, Chromosomes & Cancer. 19: 233-40. PMID 9258658 DOI: 10.1002/(Sici)1098-2264(199708)19:4<233::Aid-Gcc5>3.0.Co;2-Y  0.326
1997 Chesi M, Nardini E, Brents LA, Schröck E, Ried T, Kuehl WM, Bergsagel PL. Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3. Nature Genetics. 16: 260-4. PMID 9207791 DOI: 10.1038/ng0797-260  0.329
1997 Veldman T, Vignon C, Schröck E, Rowley JD, Ried T. Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotyping. Nature Genetics. 15: 406-10. PMID 9090389 DOI: 10.1038/ng0497-406  0.367
1997 Schwendel A, Langreck H, Reichel M, Schröck E, Ried T, Dietel M, Petersen I. Primary small-cell lung carcinomas and their metastases are characterized by a recurrent pattern of genetic alterations. International Journal of Cancer. 74: 86-93. PMID 9036875 DOI: 10.1002/(Sici)1097-0215(19970220)74:1<86::Aid-Ijc15>3.0.Co;2-G  0.436
1997 Petersen I, Langreck H, Wolf G, Schwendel A, Psille R, Vogt P, Reichel MB, Ried T, Dietel M. Small-cell lung cancer is characterized by a high incidence of deletions on chromosomes 3p, 4q, 5q, 10q, 13q and 17p. British Journal of Cancer. 75: 79-86. PMID 9000602 DOI: 10.1038/Bjc.1997.13  0.45
1997 Eils R, Dietzel S, Bertin E, Schröck E, Speicher MR, Ried T, Robert-Nicoud M, Cremer C, Cremer T. Three-dimensional reconstruction of painted human interphase chromosomes: active and inactive X chromosome territories have similar volumes but differ in shape and surface structure. The Journal of Cell Biology. 135: 1427-40. PMID 8978813 DOI: 10.1083/Jcb.135.6.1427  0.384
1997 Knutsen T, Mickley L, Ried T, du Manoir S, Schröck E, Green E, MacVille M, Spengler B, Biedler J, Fojo A. Fish and CGH studies of gene rearrangement and amplification in drug resistance Cancer Genetics and Cytogenetics. 98: 160. DOI: 10.1016/S0165-4608(97)90285-5  0.303
1997 Ried T, Schröck E, Heselmeyer K, du Manoir S, Macville M, Auer G. Stage specific chromosomal aberrations in solid tumor progression Cancer Genetics and Cytogenetics. 98: 149. DOI: 10.1016/S0165-4608(97)90242-9  0.421
1996 Liyanage M, Coleman A, du Manoir S, Veldman T, McCormack S, Dickson RB, Barlow C, Wynshaw-Boris A, Janz S, Wienberg J, Ferguson-Smith MA, Schröck E, Ried T. Multicolour spectral karyotyping of mouse chromosomes. Nature Genetics. 14: 312-5. PMID 8896561 DOI: 10.1038/Ng1196-312  0.358
1996 Giollant M, Bertrand S, Verrelle P, Tchirkov A, du Manoir S, Ried T, Mornex F, Doré JF, Cremer T, Malet P. Characterization of double minute chromosomes' DNA content in a human high grade astrocytoma cell line by using comparative genomic hybridization and fluorescence in situ hybridization. Human Genetics. 98: 265-70. PMID 8707292 DOI: 10.1007/S004390050205  0.499
1996 Ried T, Knutzen R, Steinbeck R, Blegen H, Schröck E, Heselmeyer K, du Manoir S, Auer G. Comparative genomic hybridization reveals a specific pattern of chromosomal gains and losses during the genesis of colorectal tumors. Genes, Chromosomes & Cancer. 15: 234-45. PMID 8703849 DOI: 10.1002/(Sici)1098-2264(199604)15:4<234::Aid-Gcc5>3.0.Co;2-2  0.486
1996 Schröck E, Blume C, Meffert MC, du Manoir S, Bersch W, Kiessling M, Lozanowa T, Thiel G, Witkowski R, Ried T, Cremer T. Recurrent gain of chromosome arm 7q in low-grade astrocytic tumors studied by comparative genomic hybridization. Genes, Chromosomes & Cancer. 15: 199-205. PMID 8703845 DOI: 10.1002/(Sici)1098-2264(199604)15:4<199::Aid-Gcc1>3.0.Co;2-X  0.454
1996 Barlow C, Hirotsune S, Paylor R, Liyanage M, Eckhaus M, Collins F, Shiloh Y, Crawley JN, Ried T, Tagle D, Wynshaw-Boris A. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell. 86: 159-71. PMID 8689683 DOI: 10.1016/S0092-8674(00)80086-0  0.348
1996 Schröck E, du Manoir S, Veldman T, Schoell B, Wienberg J, Ferguson-Smith MA, Ning Y, Ledbetter DH, Bar-Am I, Soenksen D, Garini Y, Ried T. Multicolor spectral karyotyping of human chromosomes. Science (New York, N.Y.). 273: 494-7. PMID 8662537 DOI: 10.1126/Science.273.5274.494  0.337
1996 Pecker I, Avraham KB, Gilbert DJ, Savitsky K, Rotman G, Harnik R, Fukao T, Schröck E, Hirotsune S, Tagle DA, Collins FS, Wynshaw-Boris A, Ried T, Copeland NG, Jenkins NA, et al. Identification and chromosomal localization of Atm, the mouse homolog of the ataxia-telangiectasia gene. Genomics. 35: 39-45. PMID 8661102 DOI: 10.1006/Geno.1996.0320  0.357
1996 Decker HJ, Neuhaus C, Jauch A, Speicher M, Ried T, Bujard M, Brauch H, Störkel S, Stöckle M, Seliger B, Huber C. Detection of a germline mutation and somatic homozygous loss of the von Hippel-Lindau tumor-suppressor gene in a family with a de novo mutation. A combined genetic study, including cytogenetics, PCR/SSCP, FISH, and CGH. Human Genetics. 97: 770-6. PMID 8641695 DOI: 10.1007/Bf02346188  0.444
1996 Schröck E, Badger P, Larson D, Erdos M, Wynshaw-Boris A, Ried T, Brody L. The murine homolog of the human breast and ovarian cancer susceptibility gene Brca1 maps to mouse chromosome 11D. Human Genetics. 97: 256-9. PMID 8566965 DOI: 10.1007/Bf02265277  0.481
1996 Heselmeyer K, Schröck E, du Manoir S, Blegen H, Shah K, Steinbeck R, Auer G, Ried T. Gain of chromosome 3q defines the transition from severe dysplasia to invasive carcinoma of the uterine cervix. Proceedings of the National Academy of Sciences of the United States of America. 93: 479-84. PMID 8552665 DOI: 10.1073/Pnas.93.1.479  0.321
1996 Zhan S, Vazquez N, Zhan S, Wientjes F, Budarf M, Schrock E, Ried T, Green E, Chanock S. Genomic structure, chromosomal localization, start of transcription, and tissue expression of the human p40-phox, a new component of the nicotinamide adenine dinucleotide phosphate-oxidase complex Blood. 88: 2714-2721. DOI: 10.1182/blood.v88.7.2714.bloodjournal8872714  0.32
1995 du Manoir S, Schröck E, Bentz M, Speicher MR, Joos S, Ried T, Lichter P, Cremer T. Quantitative analysis of comparative genomic hybridization. Cytometry. 19: 27-41. PMID 7705182 DOI: 10.1002/Cyto.990190105  0.443
1995 Schröck E, du Manoir S, Theil G, Ried T. Detection of genetic imbalances in human brain tumors using karyotyping, interphase cytogenetics, and comparative genomic hybridization Cancer Genetics and Cytogenetics. 84: 134. DOI: 10.1016/0165-4608(96)85228-9  0.376
1995 Decker HJ, Bauer C, Jauch A, Speicher M, Ried T, Bujard M, Brauch H, Störkel S, Schwerdte R, Höfler H, Seliger B, Stöckle M, Hohenfellner R, Huber C. Molecular and cytogenetic studies on sporadic and familial forms of renal cell carcinomas : Detection of homozygous loss of the Von Hippel-Lindau tumor-suppressor gene by cytogenetics, PCR/SSCP, FISH with 3p YAC probes and CGH Cancer Genetics and Cytogenetics. 84: 130. DOI: 10.1016/0165-4608(96)85213-7  0.375
1994 Ashley T, Ried T, Ward DC. Detection of nondisjunction and recombination in meiotic and postmeiotic cells from XYSxr [XY,Tp(Y)1Ct] mice using multicolor fluorescence in situ hybridization. Proceedings of the National Academy of Sciences of the United States of America. 91: 524-8. PMID 8290558 DOI: 10.1073/Pnas.91.2.524  0.583
1994 Speicher MR, du Manoir S, Schröck E, Holtgreve-Grez H, Schoell B, Lengauer C, Cremer T, Ried T. Molecular cytogenetic analysis of formalin-fixed, paraffin-embedded solid tumors by comparative genomic hybridization after universal DNA-amplification. Human Molecular Genetics. 2: 1907-14. PMID 8281155 DOI: 10.1093/Hmg/2.11.1907  0.453
1994 Hoefler G, Forstner M, McGuinness MC, Hulla W, Hiden M, Krisper P, Kenner L, Ried T, Lengauer C, Zechner R. cDNA cloning of the human peroxisomal enoyl-CoA hydratase: 3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme and localization to chromosome 3q26.3-3q28: a free left Alu Arm is inserted in the 3' noncoding region. Genomics. 19: 60-7. PMID 8188243 DOI: 10.1006/Geno.1994.1013  0.359
1994 Tocharoentanaphol C, Cremer M, Schröck E, Blonden L, Kilian K, Cremer T, Ried T. Multicolor fluorescence in situ hybridization on metaphase chromosomes and interphase Halo-preparations using cosmid and YAC clones for the simultaneous high resolution mapping of deletions in the dystrophin gene. Human Genetics. 93: 229-35. PMID 8125473 DOI: 10.1007/Bf00212014  0.418
1994 Lichter P, Ried T. Molecular analysis of chromosome aberrations. In situ hybridization. Methods in Molecular Biology (Clifton, N.J.). 29: 449-78. PMID 8032422 DOI: 10.1385/0-89603-289-2:449  0.439
1994 Levy FO, Holtgreve-Grez H, Tasken K, Solberg R, Ried T, Gudermann T. Assignment of the gene encoding the 5-HT(1E) serotonin receptor (S31) (locus HTR1E) to human chromosome 6q14-q15 Genomics. 22: 637-640. PMID 8001977 DOI: 10.1006/Geno.1994.1439  0.457
1994 Cremer T, Kurz A, Zirbel R, Dietzel S, Rinke B, Schröck E, Speicher MR, Mathieu U, Jauch A, Emmerich P, Scherthan H, Ried T, Cremer C, Lichter P. Role of chromosome territories in the functional compartmentalization of the cell nucleus. Cold Spring Harbor Symposia On Quantitative Biology. 58: 777-92. PMID 7525149 DOI: 10.1101/Sqb.1993.058.01.085  0.414
1994 Taruscio D, Carcangiu ML, Ried T, Ward DC. Numerical chromosomal aberrations in thyroid tumors detected by double fluorescence in situ hybridization. Genes, Chromosomes & Cancer. 9: 180-5. PMID 7515660 DOI: 10.1002/Gcc.2870090306  0.6
1994 Giollant M, Ried T, Bertrand S, Malet P. Use of karyotyping, FISH and CGH for characterization of genome imbalances in tumor cells Cancer Genetics and Cytogenetics. 77: 163. DOI: 10.1016/0165-4608(94)90288-7  0.394
1993 Vaughan KT, Weber FE, Ried T, Ward DC, Reinach FC, Fischman DA. Human myosin-binding protein H (MyBP-H): complete primary sequence, genomic organization, and chromosomal localization. Genomics. 16: 34-40. PMID 8486381 DOI: 10.1006/Geno.1993.1136  0.549
1993 Ried T, Rudy B, Vega-Saenz de Miera E, Lau D, Ward DC, Sen K. Localization of a highly conserved human potassium channel gene (NGK2-KV4; KCNC1) to chromosome 11p15. Genomics. 15: 405-11. PMID 8449507 DOI: 10.1006/Geno.1993.1075  0.545
1993 Baldini A, Ried T, Shridhar V, Ogura K, D'Aiuto L, Rocchi M, Ward DC. An alphoid DNA sequence conserved in all human and great ape chromosomes: evidence for ancient centromeric sequences at human chromosomal regions 2q21 and 9q13. Human Genetics. 90: 577-83. PMID 8444464 DOI: 10.1007/Bf00202474  0.563
1993 Ried T, Lengauer C, Lipp M, Fischer C, Cremer T, Ward DC. Evaluation of the utility of interphase cytogenetics to detect residual cells with a malignant genotype in mixed cell populations: a Burkitt lymphoma model. Dna and Cell Biology. 12: 637-43. PMID 8397822 DOI: 10.1089/Dna.1993.12.637  0.546
1993 Ried T, Arnold N, Ward DC, Wienberg J. Comparative high-resolution mapping of human and primate chromosomes by fluorescence in situ hybridization. Genomics. 18: 381-6. PMID 8288242 DOI: 10.1006/Geno.1993.1479  0.584
1992 Ried T, Baldini A, Rand TC, Ward DC. Simultaneous visualization of seven different DNA probes by in situ hybridization using combinatorial fluorescence and digital imaging microscopy. Proceedings of the National Academy of Sciences of the United States of America. 89: 1388-92. PMID 1741394 DOI: 10.1073/Pnas.89.4.1388  0.586
1992 Lichter P, Bray P, Ried T, Dawid IB, Ward DC. Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. Genomics. 13: 999-1007. PMID 1505991 DOI: 10.1016/0888-7543(92)90013-I  0.573
1992 Bellefroid EJ, Ried T, Rivière M, Marine JC, Levan G, Szpirer J, Szpirer C, Ward DC, Martial JA. Localization of the human KRAB finger gene ZNF117 (HPF9) to chromosome 7q11.2. Genomics. 14: 780-1. PMID 1427907 DOI: 10.1016/S0888-7543(05)80185-5  0.605
1992 Ried T, Lengauer C, Cremer T, Wiegant J, Raap AK, van der Ploeg M, Groitl P, Lipp M. Specific metaphase and interphase detection of the breakpoint region in 8q24 of Burkitt lymphoma cells by triple-color fluorescence in situ hybridization. Genes, Chromosomes & Cancer. 4: 69-74. PMID 1377011 DOI: 10.1002/Gcc.2870040109  0.754
1992 Ried T, Landes G, Dackowski W, Klinger K, Ward DC. Multicolor fluorescence in situ hybridization for the simultaneous detection of probe sets for chromosomes 13, 18, 21, X and Y in uncultured amniotic fluid cells. Human Molecular Genetics. 1: 307-13. PMID 1303206 DOI: 10.1093/Hmg/1.5.307  0.59
1991 Wiegant J, Ried T, Nederlof PM, van der Ploeg M, Tanke HJ, Raap AK. In situ hybridization with fluoresceinated DNA. Nucleic Acids Research. 19: 3237-41. PMID 2062640 DOI: 10.1093/Nar/19.12.3237  0.701
1991 Rudy B, Sen K, Vega-Saenz de Miera E, Lau D, Ried T, Ward DC. Cloning of a human cDNA expressing a high voltage-activating, TEA-sensitive, type-A K+ channel which maps to chromosome 1 band p21. Journal of Neuroscience Research. 29: 401-12. PMID 1920536 DOI: 10.1002/Jnr.490290316  0.462
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