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Kevin J. Tidgewell - Publications

Affiliations: 
Duquesne University, Pittsburgh, PA, United States 
Area:
Marine Natural Products, CNS Active compounds, GPCR ligands
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Tayler NM, Boya CA, Herrera L, Moy J, Ng M, Pineda L, Almanza A, Rosero S, Coronado LM, Correa R, Santamaría R, Caballero Z, Durant-Archibold AA, Tidgewell KJ, Balunas MJ, et al. Analysis of the antiparasitic and anticancer activity of the coconut palm (Cocos nucifera L. ARECACEAE) from the natural reserve of Punta Patiño, Darién. Plos One. 14: e0214193. PMID 30939131 DOI: 10.1371/Journal.Pone.0214193  0.391
2018 Rague AL, Parker SJ, Tidgewell KJ. Evaluating Marine Cyanobacteria as a Source for CNS Receptor Ligands. Molecules (Basel, Switzerland). 23. PMID 30336553 DOI: 10.3390/Molecules23102665  0.359
2018 Rague A, Tidgewell K. Pharmacophore Comparison and Development of Recently Discovered Long Chain Arylpiperazine and Sulfonamide Based 5-HT7 Ligands. Mini-Reviews in Medicinal Chemistry. 18: 552-560. PMID 28901854 DOI: 10.2174/1389557517666170913111533  0.325
2016 Ahmed KT, Gayathri C, Pineda L, Spadafora C, Gil R, Gerwick WH, Tidgewell KJ. Isolation, structure elucidation, and total synthesis of an N-methylated tetrapeptide from a Panamanian marine cyanobacterium. Planta Medica. 81: S1-S381. PMID 27975840 DOI: 10.1055/S-0036-1596639  0.467
2016 Lax NC, Ahmed KT, Ignatz CM, Spadafora C, Kolber BJ, Tidgewell KJ. Marine cyanobacteria-derived serotonin receptor 2C active fraction induces psychoactive behavioral effects in mice. Pharmaceutical Biology. 1-9. PMID 27181630 DOI: 10.1080/13880209.2016.1181659  0.351
2012 Balunas MJ, Grosso MF, Villa FA, Engene N, McPhail KL, Tidgewell K, Pineda LM, Gerwick L, Spadafora C, Kyle DE, Gerwick WH. Coibacins A-D, antileishmanial marine cyanobacterial polyketides with intriguing biosynthetic origins. Organic Letters. 14: 3878-81. PMID 22794317 DOI: 10.1021/Ol301607Q  0.705
2012 Lamb K, Tidgewell K, Simpson DS, Bohn LM, Prisinzano TE. Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology. Drug and Alcohol Dependence. 121: 181-8. PMID 22119134 DOI: 10.1016/J.Drugalcdep.2011.10.026  0.663
2012 Tidgewell K, Moy J, Herrera L, Spadafora C, Gerwick W. Secondary metabolites from Panamanian mat forming cyanobacteria Planta Medica. 78. DOI: 10.1055/S-0032-1320708  0.436
2010 Tidgewell K, Engene N, Byrum T, Media J, Doi T, Valeriote FA, Gerwick WH. Evolved diversification of a modular natural product pathway: apratoxins F and G, two cytotoxic cyclic depsipeptides from a Palmyra collection of Lyngbya bouillonii. Chembiochem : a European Journal of Chemical Biology. 11: 1458-66. PMID 20512792 DOI: 10.1002/Cbic.201000070  0.709
2010 Gutiérrez M, Tidgewell K, Capson TL, Engene N, Almanza A, Schemies J, Jung M, Gerwick WH. Malyngolide dimer, a bioactive symmetric cyclodepside from the panamanian marine cyanobacterium Lyngbya majuscula. Journal of Natural Products. 73: 709-11. PMID 20158242 DOI: 10.1021/Np9005184  0.717
2010 Balunas MJ, Linington RG, Tidgewell K, Fenner AM, Ureña LD, Togna GD, Kyle DE, Gerwick WH. Dragonamide E, a modified linear lipopeptide from Lyngbya majuscula with antileishmanial activity. Journal of Natural Products. 73: 60-6. PMID 20030365 DOI: 10.1021/Np900622M  0.726
2010 Tidgewell K, Clark BR, Gerwick WH. The natural products chemistry of cyanobacteria Comprehensive Natural Products Ii: Chemistry and Biology. 2: 141-188.  0.358
2008 Tidgewell K, Groer CE, Harding WW, Lozama A, Schmidt M, Marquam A, Hiemstra J, Partilla JS, Dersch CM, Rothman RB, Bohn LM, Prisinzano TE. Herkinorin analogues with differential beta-arrestin-2 interactions. Journal of Medicinal Chemistry. 51: 2421-31. PMID 18380425 DOI: 10.1021/Jm701162G  0.771
2007 Holden KG, Tidgewell K, Marquam A, Rothman RB, Navarro H, Prisinzano TE. Synthetic studies of neoclerodane diterpenes from Salvia divinorum: exploration of the 1-position. Bioorganic & Medicinal Chemistry Letters. 17: 6111-5. PMID 17904842 DOI: 10.1016/J.Bmcl.2007.09.050  0.665
2007 Xu H, Partilla JS, Wang X, Rutherford JM, Tidgewell K, Prisinzano TE, Bohn LM, Rothman RB. A comparison of noninternalizing (herkinorin) and internalizing (DAMGO) mu-opioid agonists on cellular markers related to opioid tolerance and dependence. Synapse (New York, N.Y.). 61: 166-75. PMID 17152090 DOI: 10.1002/Syn.20356  0.641
2007 Groer CE, Tidgewell K, Moyer RA, Harding WW, Rothman RB, Prisinzano TE, Bohn LM. An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization. Molecular Pharmacology. 71: 549-57. PMID 17090705 DOI: 10.1124/Mol.106.028258  0.768
2007 Butelman ER, Mandau M, Tidgewell K, Prisinzano TE, Yuferov V, Kreek MJ. Effects of salvinorin A, a kappa-opioid hallucinogen, on a neuroendocrine biomarker assay in nonhuman primates with high kappa-receptor homology to humans. The Journal of Pharmacology and Experimental Therapeutics. 320: 300-6. PMID 17060493 DOI: 10.1124/Jpet.106.112417  0.633
2007 Rothman RB, Murphy DL, Xu H, Godin JA, Dersch CM, Partilla JS, Tidgewell K, Schmidt M, Prisinzano TE. Salvinorin A: allosteric interactions at the mu-opioid receptor. The Journal of Pharmacology and Experimental Therapeutics. 320: 801-10. PMID 17060492 DOI: 10.1124/Jpet.106.113167  0.653
2007 Bohn LM, Groer CE, Tidgewell K, Moyer R, Harding WW, Prisinzano TE. Mu opioid receptor activation without arrestin‐interactions; a pharmacological approach. The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A426-A  0.764
2006 Tidgewell K, Harding WW, Lozama A, Cobb H, Shah K, Kannan P, Dersch CM, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE. Synthesis of salvinorin A analogues as opioid receptor probes. Journal of Natural Products. 69: 914-8. PMID 16792410 DOI: 10.1021/Np060094B  0.775
2006 Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Dersch CM, Rothman RB, Prisinzano TE. Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring. Bioorganic & Medicinal Chemistry Letters. 16: 3170-4. PMID 16621556 DOI: 10.1016/J.Bmcl.2006.03.062  0.719
2006 Harding WW, Schmidt M, Tidgewell K, Kannan P, Holden KG, Gilmour B, Navarro H, Rothman RB, Prisinzano TE. Synthetic studies of neoclerodane diterpenes from Salvia divinorum: semisynthesis of salvinicins A and B and other chemical transformations of salvinorin A. Journal of Natural Products. 69: 107-12. PMID 16441078 DOI: 10.1021/Np050398I  0.785
2005 Prisinzano TE, Tidgewell K, Harding WW. Kappa opioids as potential treatments for stimulant dependence. The Aaps Journal. 7: E592-9. PMID 16353938 DOI: 10.1208/Aapsj070361  0.723
2005 Schmidt MD, Schmidt MS, Butelman ER, Harding WW, Tidgewell K, Murry DJ, Kreek MJ, Prisinzano TE. Pharmacokinetics of the plant-derived kappa-opioid hallucinogen salvinorin A in nonhuman primates. Synapse (New York, N.Y.). 58: 208-10. PMID 16138318 DOI: 10.1002/Syn.20191  0.705
2005 Harding WW, Tidgewell K, Byrd N, Cobb H, Dersch CM, Butelman ER, Rothman RB, Prisinzano TE. Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands. Journal of Medicinal Chemistry. 48: 4765-71. PMID 16033256 DOI: 10.1021/Jm048963M  0.775
2005 Harding WW, Tidgewell K, Schmidt M, Shah K, Dersch CM, Snyder J, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE. Salvinicins A and B, new neoclerodane diterpenes from Salvia divinorum. Organic Letters. 7: 3017-20. PMID 15987194 DOI: 10.1021/Ol0510522  0.708
2005 Schmidt MS, Prisinzano TE, Tidgewell K, Harding W, Butelman ER, Kreek MJ, Murry DJ. Determination of Salvinorin A in body fluids by high performance liquid chromatography-atmospheric pressure chemical ionization. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 818: 221-5. PMID 15734162 DOI: 10.1016/J.Jchromb.2004.12.041  0.688
2005 Harding WW, Tidgewell K, Schmidt M, Shah K, Dersch CM, Snyder J, Parrish D, Deschamps JR, Rothman RB, Prisinzano TE. Salvinicins A (I) and B (II), New Neoclerodane Diterpenes from Salvia divinorum. Cheminform. 36. DOI: 10.1002/chin.200547181  0.663
2004 Tidgewell K, Harding WW, Schmidt M, Holden KG, Murry DJ, Prisinzano TE. A facile method for the preparation of deuterium labeled salvinorin A: synthesis of [2,2,2-2H3]-salvinorin A. Bioorganic & Medicinal Chemistry Letters. 14: 5099-102. PMID 15380207 DOI: 10.1016/J.Bmcl.2004.07.081  0.696
2004 Prisinzano T, Podobinski J, Tidgewell K, Luo M, Swenson D. Synthesis and determination of the absolute configuration of the enantiomers of modafinil Tetrahedron: Asymmetry. 15: 1053-1058. DOI: 10.1016/J.Tetasy.2004.01.039  0.523
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