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Gary N. Chan, Ph.D. - Publications

Affiliations: 
2013 Pharmaceutical Sciences University of Toronto, Toronto, ON, Canada 
Area:
Pharmacology
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Banks DB, Chan GN, Evans RA, Miller DS, Cannon RE. Lysophosphatidic acid and amitriptyline signal through LPA1R to reduce P-glycoprotein transport at the blood-brain barrier. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17705786. PMID 28447863 DOI: 10.1177/0271678X17705786  0.503
2017 Chan GN, Cannon RE. Assessment of Ex Vivo Transport Function in Isolated Rodent Brain Capillaries. Current Protocols in Pharmacology. 76: 7.16.1-7.16.16. PMID 28306152 DOI: 10.1002/Cpph.21  0.427
2016 Chan GN, Evans R, Banks D, Mesev E, Miller DS, Cannon RE. Selective induction of P-glycoprotein at the CNS barriers during symptomatic stage of an ALS animal model. Neuroscience Letters. PMID 28011392 DOI: 10.1016/J.Neulet.2016.12.049  0.434
2016 More VR, Campos CR, Evans RA, Oliver KD, Chan GN, Miller DS, Cannon RE. PPAR-α, a lipid-sensing transcription factor, regulates blood-brain barrier efflux transporter expression. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 27193034 DOI: 10.1177/0271678X16650216  0.537
2014 Robillard KR, Chan GN, Zhang G, la Porte C, Cameron W, Bendayan R. Role of P-glycoprotein in the distribution of the HIV protease inhibitor atazanavir in the brain and male genital tract. Antimicrobial Agents and Chemotherapy. 58: 1713-22. PMID 24379203 DOI: 10.1128/Aac.02031-13  0.658
2014 Ashraf T, Robillard K, Chan GN, Bendayan R. Role of CNS transporters in the pharmacotherapy of HIV-1 associated neurological disorders. Current Pharmaceutical Design. 20: 1543-63. PMID 23789949 DOI: 10.2174/13816128113199990464  0.684
2013 Chan GN, Saldivia V, Yang Y, Pang H, de Lannoy I, Bendayan R. In vivo induction of P-glycoprotein expression at the mouse blood-brain barrier: an intracerebral microdialysis study. Journal of Neurochemistry. 127: 342-52. PMID 23777437 DOI: 10.1111/jnc.12344  0.661
2013 Chan GN, Hoque MT, Bendayan R. Role of nuclear receptors in the regulation of drug transporters in the brain. Trends in Pharmacological Sciences. 34: 361-72. PMID 23769624 DOI: 10.1016/j.tips.2013.05.004  0.694
2012 Durk MR, Chan GN, Campos CR, Peart JC, Chow EC, Lee E, Cannon RE, Bendayan R, Miller DS, Pang KS. 1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells. Journal of Neurochemistry. 123: 944-53. PMID 23035695 DOI: 10.1111/Jnc.12041  0.571
2011 Chan GN, Hoque MT, Cummins CL, Bendayan R. Regulation of P-glycoprotein by orphan nuclear receptors in human brain microvessel endothelial cells. Journal of Neurochemistry. 118: 163-75. PMID 21517853 DOI: 10.1111/J.1471-4159.2011.07288.X  0.611
2011 Chan GN, Bendayan R. Molecular and functional characterization of P-glycoprotein in vitro. Methods in Molecular Biology (Clifton, N.J.). 686: 313-36. PMID 21082379 DOI: 10.1007/978-1-60761-938-3_15  0.63
2010 Kis O, Robillard K, Chan GN, Bendayan R. The complexities of antiretroviral drug-drug interactions: role of ABC and SLC transporters. Trends in Pharmacological Sciences. 31: 22-35. PMID 20004485 DOI: 10.1016/J.Tips.2009.10.001  0.663
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