Kevin D. Costa, Ph.D. - Publications

Affiliations: 
Bioengineering University of California, San Diego, La Jolla, CA 
Area:
cardiac biomechanics, tissue engineering, atomic force microscopy

98 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wong AO, Wong N, Geng L, Chow MZ, Lee EK, Wu H, Khine M, Kong CW, Costa KD, Keung W, Cheung YF, Li RA. Combinatorial Treatment of Human Cardiac Engineered Tissues With Biomimetic Cues Induces Functional Maturation as Revealed by Optical Mapping of Action Potentials and Calcium Transients. Frontiers in Physiology. 11: 165. PMID 32226389 DOI: 10.3389/Fphys.2020.00165  0.343
2019 Keung W, Chan PK, Backeris P, Lee EK, Wong N, Wong GK, Chan CW, Fermini B, Costa KD, Li RA. Human cardiac ventricular organoid chambers and tissue strips from pluripotent stem cells as a two-tiered assay for inotropic responses: A blinded validation. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31962924 DOI: 10.1016/J.Vascn.2019.05.174  0.367
2019 Wong AO, Lieu DK, Wong GK, Gurung B, Tse WW, Costa KD, Chan CW, Nabhan JD, Li RA. Modeling cardiac dysfunction of Friedreich's ataxia using ventricular sheets, tissues and chambers engineered from human pluripotent stem cells. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31962923 DOI: 10.1016/J.Vascn.2019.05.175  0.371
2019 Shum A, Wong AO, Chan CW, Costa KD, Khine M, Kong CW, Li RA. Directly visualizing drug-induced arrhythmias with aligned human pluripotent stem cell-based ventricular cardiac anisotropic sheet. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31962922 DOI: 10.1016/J.Vascn.2019.05.176  0.33
2019 Lee EK, Tran DD, Keung W, Chan PK, Wong GK, Chan CW, Costa KD, Khine M, Li RA. Automated drug classification by machine learning analysis of drug screening data from human pluripotent stem cell-derived engineered cardiac tissue assays. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31962920 DOI: 10.1016/J.Vascn.2019.05.177  0.3
2019 Li RA, Keung W, Cashman T, Backeris P, Johnson BV, Bardot ES, Wong AO, Chan PK, Chan CW, Costa KD. "Human heart-in-a-Jar": An electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31962919 DOI: 10.1016/J.Vascn.2019.05.178  0.338
2019 Wong AO, Chan CW, Costa KD, Li RA. Controlled physiomimetic preload augments inotropic sensitivity and contractile phenotypes in human pluripotent stem cell-derived engineered cardiac tissues and chambers. Journal of Pharmacological and Toxicological Methods. 99: 106595. PMID 31962918 DOI: 10.1016/J.Vascn.2019.05.179  0.358
2019 Murphy JF, Mayourian J, Stillitano F, Munawar S, Broughton KM, Agullo-Pascual E, Sussman MA, Hajjar RJ, Costa KD, Turnbull IC. Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues. Stem Cell Research & Therapy. 10: 373. PMID 31801634 DOI: 10.1186/S13287-019-1486-4  0.362
2019 Wong AO, Wong G, Shen M, Chow MZ, Tse WW, Gurung B, Mak SY, Lieu DK, Costa KD, Chan CW, Martelli A, Nabhan JF, Li RA. Correlation between frataxin expression and contractility revealed by in vitro Friedreich's ataxia cardiac tissue models engineered from human pluripotent stem cells. Stem Cell Research & Therapy. 10: 203. PMID 31286988 DOI: 10.1186/S13287-019-1305-Y  0.386
2019 Chow MZ, Sadrian SN, Keung W, Geng L, Ren L, Kong CW, Wong AO, Hulot JS, Chen CS, Costa KD, Hajjar RJ, Li RA. Modulation of chromatin remodeling proteins SMYD1 and SMARCD1 promotes contractile function of human pluripotent stem cell-derived ventricular cardiomyocyte in 3D-engineered cardiac tissues. Scientific Reports. 9: 7502. PMID 31097748 DOI: 10.1038/S41598-019-42953-W  0.38
2019 Keung W, Chan PKW, Backeris PC, Lee EK, Wong N, Wong AOT, Wong GKY, Chan CWY, Fermini B, Costa KD, Li RA. Human cardiac ventricular-like organoid chambers and tissue strips from pluripotent stem cells as a two-tiered assay for inotropic responses. Clinical Pharmacology and Therapeutics. PMID 30723889 DOI: 10.1002/Cpt.1385  0.347
2018 Turnbull IC, Mayourian J, Murphy JF, Stillitano F, Ceholski DK, Costa KD. Cardiac Tissue Engineering Models of Inherited and Acquired Cardiomyopathies. Methods in Molecular Biology (Clifton, N.J.). 1816: 145-159. PMID 29987817 DOI: 10.1007/978-1-4939-8597-5_11  0.378
2018 Mayourian J, Sobie EA, Costa KD. An Introduction to Computational Modeling of Cardiac Electrophysiology and Arrhythmogenicity. Methods in Molecular Biology (Clifton, N.J.). 1816: 17-35. PMID 29987808 DOI: 10.1007/978-1-4939-8597-5_2  0.361
2018 Lee JJ, Rao S, Kaushik G, Azeloglu EU, Costa KD. Dehomogenized Elastic Properties of Heterogeneous Layered Materials in AFM Indentation Experiments. Biophysical Journal. 114: 2717-2731. PMID 29874620 DOI: 10.1016/J.Bpj.2018.04.036  0.643
2018 Ceholski DK, Turnbull IC, Kong CW, Koplev S, Mayourian J, Gorski PA, Stillitano F, Skodras AA, Nonnenmacher M, Cohen N, Björkegren JLM, Stroik DR, Cornea RL, Thomas DD, Li RA, ... Costa KD, et al. Functional and transcriptomic insights into pathogenesis of R9C phospholamban mutation using human induced pluripotent stem cell-derived cardiomyocytes. Journal of Molecular and Cellular Cardiology. PMID 29752948 DOI: 10.1016/J.Yjmcc.2018.05.007  0.316
2018 Li RA, Keung W, Cashman TJ, Backeris PC, Johnson BV, Bardot ES, Wong AOT, Chan PKW, Chan CWY, Costa KD. Bioengineering an electro-mechanically functional miniature ventricular heart chamber from human pluripotent stem cells. Biomaterials. 163: 116-127. PMID 29459321 DOI: 10.1016/J.Biomaterials.2018.02.024  0.412
2018 Mayourian J, Ceholski DK, Gonzalez DM, Cashman TJ, Sahoo S, Hajjar RJ, Costa KD. Physiologic, Pathologic, and Therapeutic Paracrine Modulation of Cardiac Excitation-Contraction Coupling. Circulation Research. 122: 167-183. PMID 29301848 DOI: 10.1161/Circresaha.117.311589  0.403
2017 Lee EK, Tran DD, Keung W, Chan P, Wong G, Chan CW, Costa KD, Li RA, Khine M. Machine Learning of Human Pluripotent Stem Cell-Derived Engineered Cardiac Tissue Contractility for Automated Drug Classification. Stem Cell Reports. PMID 29033305 DOI: 10.1016/J.Stemcr.2017.09.008  0.356
2017 Ceholski DK, Turnbull IC, Pothula V, Lecce L, Jarrah AA, Kho C, Lee A, Hadri L, Costa KD, Hajjar RJ, Tarzami ST. CXCR4 and CXCR7 play distinct roles in cardiac lineage specification and pharmacologic β-adrenergic response. Stem Cell Research. 23: 77-86. PMID 28711757 DOI: 10.1016/J.Scr.2017.06.015  0.322
2017 Mayourian J, Cashman TJ, Ceholski DK, Johnson BV, Sachs D, Kaji DA, Sahoo S, Hare JM, Hajjar RJ, Sobie EA, Costa KD. Experimental and Computational Insight into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity. Circulation Research. PMID 28642329 DOI: 10.1161/Circresaha.117.310796  0.37
2017 Mayourian J, Cashman TJ, Johnson BV, Sachs DM, Kaji DA, Sobie EA, Costa KD. Human Mesenchymal Stem Cell Paracrine Signaling Counteracts Heterocellular Coupling Effects on Cardiac Contractility and Arrhythomgenicity Biophysical Journal. 112: 162a. DOI: 10.1016/J.Bpj.2016.11.890  0.393
2016 Zhou N, Lee JJ, Stoll S, Ma B, Wiener R, Wang C, Costa KD, Qiu H. Inhibition of SRF/myocardin reduces aortic stiffness by targeting vascular smooth muscle cell stiffening in hypertension. Cardiovascular Research. PMID 28003268 DOI: 10.1093/Cvr/Cvw222  0.542
2016 Shum AM, Che H, Wong AO, Zhang C, Wu H, Chan CW, Costa K, Khine M, Kong CW, Li RA. A Micropatterned Human Pluripotent Stem Cell-Based Ventricular Cardiac Anisotropic Sheet for Visualizing Drug-Induced Arrhythmogenicity. Advanced Materials (Deerfield Beach, Fla.). PMID 27805726 DOI: 10.1002/Adma.201602448  0.339
2016 Mayourian J, Savizky RM, Sobie EA, Costa KD. Modeling Electrophysiological Coupling and Fusion between Human Mesenchymal Stem Cells and Cardiomyocytes. Plos Computational Biology. 12: e1005014. PMID 27454812 DOI: 10.1371/Journal.Pcbi.1005014  0.353
2016 Stillitano F, Turnbull IC, Karakikes I, Nonnenmacher M, Backeris P, Hulot JS, Kranias EG, Hajjar RJ, Costa KD. Genomic correction of familial cardiomyopathy in human engineered cardiac tissues. European Heart Journal. PMID 27450564 DOI: 10.1093/Eurheartj/Ehw307  0.336
2016 Cashman TJ, Josowitz R, Gelb BD, Li RA, Dubois NC, Costa KD. Construction of Defined Human Engineered Cardiac Tissues to Study Mechanisms of Cardiac Cell Therapy. Journal of Visualized Experiments : Jove. PMID 26967678 DOI: 10.3791/53447  0.418
2016 Cashman TJ, Josowitz R, Johnson BV, Gelb BD, Costa KD. Human Engineered Cardiac Tissues Created Using Induced Pluripotent Stem Cells Reveal Functional Characteristics of BRAF-Mediated Hypertrophic Cardiomyopathy. Plos One. 11: e0146697. PMID 26784941 DOI: 10.1371/Journal.Pone.0146697  0.41
2016 Mayourian J, Savizky RM, Sobie EA, Costa KD. Modeling Electrophysiological Interactions between Mesenchymal Stem Cells and Cardiomyocytes for Improved Cell Delivery Cardiotherapeutics Biophysical Journal. 110: 271a. DOI: 10.1016/J.Bpj.2015.11.1475  0.346
2015 Kerscher P, Turnbull IC, Hodge AJ, Kim J, Seliktar D, Easley CJ, Costa KD, Lipke EA. Direct hydrogel encapsulation of pluripotent stem cells enables ontomimetic differentiation and growth of engineered human heart tissues. Biomaterials. 83: 383-395. PMID 26826618 DOI: 10.1016/J.Biomaterials.2015.12.011  0.39
2015 Chen G, Li S, Karakikes I, Ren L, Chow MZ, Chopra A, Keung W, Yan B, Chan CW, Costa KD, Kong CW, Hajjar RJ, Chen CS, Li RA. Phospholamban as a crucial determinant of the inotropic response of human pluripotent stem cell-derived ventricular cardiomyocytes and engineered 3-dimensional tissue constructs. Circulation. Arrhythmia and Electrophysiology. 8: 193-202. PMID 25504561 DOI: 10.1161/Circep.114.002049  0.337
2015 Ishikawa K, Fish K, Aguero J, Yaniz-Galende E, Jeong D, Kho C, Tilemann L, Fish L, Liang L, Eltoukhy AA, Anderson DG, Zsebo K, Costa KD, Hajjar RJ. Stem cell factor gene transfer improves cardiac function after myocardial infarction in swine. Circulation. Heart Failure. 8: 167-74. PMID 25342737 DOI: 10.1161/Circheartfailure.114.001711  0.337
2015 Lee J, Rao S, Galatioto J, Ramirez F, Costa KD. AFM Reveals Age-Dependent Micromechanical Degradation of Cardiopulmonary Tissues in a Mouse Model of Marfan Syndrome Biophysical Journal. 108: 295a-296a. DOI: 10.1016/J.Bpj.2014.11.1609  0.303
2014 Zhu R, Blazeski A, Poon E, Costa KD, Tung L, Boheler KR. Physical developmental cues for the maturation of human pluripotent stem cell-derived cardiomyocytes. Stem Cell Research & Therapy. 5: 117. PMID 25688759 DOI: 10.1186/Scrt507  0.335
2014 Turnbull IC, Karakikes I, Serrao GW, Backeris P, Lee JJ, Xie C, Senyei G, Gordon RE, Li RA, Akar FG, Hajjar RJ, Hulot JS, Costa KD. Advancing functional engineered cardiac tissues toward a preclinical model of human myocardium. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 644-54. PMID 24174427 DOI: 10.1096/Fj.13-228007  0.607
2014 Rao S, Chiu E, Cook JR, Lee J, Bénard L, Hajjar RJ, Ramirez F, Costa KD. Multi-Scale Biomechanics in a Marfan Syndrome Model of Dilated Cardiomyopathy Biophysical Journal. 106: 645a. DOI: 10.1016/J.Bpj.2013.11.3569  0.382
2013 Boycott HE, Barbier CS, Eichel CA, Costa KD, Martins RP, Louault F, Dilanian G, Coulombe A, Hatem SN, Balse E. Shear stress triggers insertion of voltage-gated potassium channels from intracellular compartments in atrial myocytes. Proceedings of the National Academy of Sciences of the United States of America. 110: E3955-64. PMID 24065831 DOI: 10.1073/Pnas.1309896110  0.313
2013 Wang J, Chen A, Lieu DK, Karakikes I, Chen G, Keung W, Chan CW, Hajjar RJ, Costa KD, Khine M, Li RA. Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias. Biomaterials. 34: 8878-86. PMID 23942210 DOI: 10.1016/J.Biomaterials.2013.07.039  0.366
2013 Cashman TJ, Gouon-Evans V, Costa KD. Mesenchymal stem cells for cardiac therapy: practical challenges and potential mechanisms. Stem Cell Reviews. 9: 254-65. PMID 22577007 DOI: 10.1007/S12015-012-9375-6  0.382
2013 Ishikawa K, Yaniz–Galende E, Aguero J, Tilemann L, Jeong D, Liang L, Fish K, Costa K, Eltoukhy E, Anderson D, Hajjar R. STEM CELL FACTOR OVER–EXPRESSION IMPROVES CARDIAC FUNCTION AFTER MYOCARDIAL INFARCTION IN SWINE Journal of the American College of Cardiology. 61: E2108. DOI: 10.1016/S0735-1097(13)62108-7  0.321
2013 Rao S, Cashman T, Costa K. Alignment of Integrin Surface Receptors with Z-Discs in Live Cardiomyocytes Revealed with High Resolution AFM Mapping Biophysical Journal. 104: 514a. DOI: 10.1016/J.Bpj.2012.11.2839  0.318
2013 Lee J, Rao S, Kaushik G, Azeloglu EU, Costa KD. Extracting Elastic Properties of Heterogeneous Layered Materials using Atomic Force Microscopy (AFM) Biophysical Journal. 104: 513a. DOI: 10.1016/J.Bpj.2012.11.2833  0.628
2012 Lieu DK, Turnbull IC, Costa KD, Li RA. Engineered human pluripotent stem cell-derived cardiac cells and tissues for electrophysiological studies. Drug Discovery Today. Disease Models. 9: e209-e217. PMID 29422934 DOI: 10.1016/J.Ddmod.2012.06.002  0.382
2012 Serrao GW, Turnbull IC, Ancukiewicz D, Kim do E, Kao E, Cashman TJ, Hadri L, Hajjar RJ, Costa KD. Myocyte-depleted engineered cardiac tissues support therapeutic potential of mesenchymal stem cells. Tissue Engineering. Part A. 18: 1322-33. PMID 22500611 DOI: 10.1089/Ten.Tea.2011.0278  0.38
2012 Turnbull IC, Lieu DK, Li RA, Costa KD. Cardiac tissue engineering using human stem cell-derived cardiomyocytes for disease modeling and drug discovery Drug Discovery Today: Disease Models. 9: e219-e227. DOI: 10.1016/J.Ddmod.2012.11.001  0.372
2012 Stillitano F, Karakikes I, Costa KD, Fish K, Hajjar RJ, Hulot JS. Preclinical animal models for testing iPSC/ESC-based heart therapy Drug Discovery Today: Disease Models. 9. DOI: 10.1016/J.Ddmod.2012.04.004  0.329
2011 Wang X, Chen S, Kong M, Wang Z, Costa KD, Li RA, Sun D. Enhanced cell sorting and manipulation with combined optical tweezer and microfluidic chip technologies. Lab On a Chip. 11: 3656-62. PMID 21918752 DOI: 10.1039/C1Lc20653B  0.325
2011 Turnbull IC, Hadri L, Rapti K, Sadek M, Liang L, Shin HJ, Costa KD, Marin ML, Hajjar RJ, Faries PL. Aortic implantation of mesenchymal stem cells after aneurysm injury in a porcine model. The Journal of Surgical Research. 170: e179-88. PMID 21764076 DOI: 10.1016/J.Jss.2011.05.042  0.301
2011 Azeloglu EU, Costa KD. Atomic force microscopy in mechanobiology: measuring microelastic heterogeneity of living cells. Methods in Molecular Biology (Clifton, N.J.). 736: 303-29. PMID 21660735 DOI: 10.1007/978-1-61779-105-5_19  0.659
2011 Ladage D, Turnbull IC, Ishikawa K, Takewa Y, Rapti K, Morel C, Karakikes I, Hadri L, Müller-Ehmsen J, Costa KD, Hajjar RJ, Kawase Y. Delivery of gelfoam-enabled cells and vectors into the pericardial space using a percutaneous approach in a porcine model Gene Therapy. 18: 979-985. PMID 21512506 DOI: 10.1038/Gt.2011.52  0.312
2010 Azeloglu EU, Costa KD. Cross-bridge cycling gives rise to spatiotemporal heterogeneity of dynamic subcellular mechanics in cardiac myocytes probed with atomic force microscopy. American Journal of Physiology. Heart and Circulatory Physiology. 298: H853-60. PMID 20023124 DOI: 10.1152/Ajpheart.00427.2009  0.671
2010 Cheung YK, Azeloglu EU, Shiovitz D, Costa KD, Seliktar D, Sia SK. Patterning micro-stiffness in cell-adhesive substrate using microfluidics-based lithography Proceedings of the 2010 Ieee 36th Annual Northeast Bioengineering Conference, Nebec 2010. DOI: 10.1109/NEBC.2010.5458111  0.635
2010 Turnbull IC, Serrao GW, Ancukiewicz D, Youmans QR, Hadri L, Hajjar RJ, Chaudhry HW, Costa KD. Mesenchymal Stem Cells Enhance Contractile Function of Myocyte-Depleted Engineered Cardiac Tissues Journal of Cardiac Failure. 16: S11. DOI: 10.1016/J.Cardfail.2010.06.037  0.364
2009 Azeloglu EU, Costa KD. Dynamic AFM elastography reveals phase dependent mechanical heterogeneity of beating cardiac myocytes. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 7180-3. PMID 19965272 DOI: 10.1109/IEMBS.2009.5335316  0.65
2009 Azeloglu EU, Kaushik G, Costa KD. Developing a hybrid computational model of AFM indentation for analysis of mechanically heterogeneous samples. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2009: 4273-6. PMID 19964629 DOI: 10.1109/IEMBS.2009.5334043  0.627
2009 Ateshian GA, Costa KD, Azeloglu EU, Morrison B, Hung CT. Continuum modeling of biological tissue growth by cell division, and alteration of intracellular osmolytes and extracellular fixed charge density. Journal of Biomechanical Engineering. 131: 101001. PMID 19831471 DOI: 10.1115/1.3192138  0.632
2009 Cheung YK, Azeloglu EU, Shiovitz DA, Costa KD, Seliktar D, Sia SK. Microscale control of stiffness in a cell-adhesive substrate using microfluidics-based lithography. Angewandte Chemie (International Ed. in English). 48: 7188-92. PMID 19479917 DOI: 10.1002/Anie.200900807  0.632
2009 Ateshian GA, Costa KD. A frame-invariant formulation of Fung elasticity. Journal of Biomechanics. 42: 781-5. PMID 19281991 DOI: 10.1016/J.Jbiomech.2009.01.015  0.301
2009 Duan Q, Angelini ED, Herz SL, Ingrassia CM, Costa KD, Holmes JW, Homma S, Laine AF. Region-based endocardium tracking on real-time three-dimensional ultrasound. Ultrasound in Medicine & Biology. 35: 256-65. PMID 18963396 DOI: 10.1016/J.Ultrasmedbio.2008.08.012  0.504
2009 Cheung Y, Azeloglu E, Shiovitz D, Costa K, Seliktar D, Sia S. Cover Picture: Microscale Control of Stiffness in a Cell-Adhesive Substrate Using Microfluidics-Based Lithography (Angew. Chem. Int. Ed. 39/2009) Angewandte Chemie International Edition. 48: 7103-7103. DOI: 10.1002/Anie.200990204  0.629
2009 Cheung Y, Azeloglu E, Shiovitz D, Costa K, Seliktar D, Sia S. Titelbild: Microscale Control of Stiffness in a Cell-Adhesive Substrate Using Microfluidics-Based Lithography (Angew. Chem. 39/2009) Angewandte Chemie. 121: 7237-7237. DOI: 10.1002/Ange.200990206  0.632
2008 Azeloglu EU, Bhattacharya J, Costa KD. Atomic force microscope elastography reveals phenotypic differences in alveolar cell stiffness. Journal of Applied Physiology (Bethesda, Md. : 1985). 105: 652-61. PMID 18535125 DOI: 10.1152/Japplphysiol.00958.2007  0.652
2008 Lee EJ, Holmes JW, Costa KD. Remodeling of engineered tissue anisotropy in response to altered loading conditions. Annals of Biomedical Engineering. 36: 1322-34. PMID 18470621 DOI: 10.1007/S10439-008-9509-9  0.581
2008 Lee EJ, Kim DE, Azeloglu EU, Costa KD. Engineered cardiac organoid chambers: toward a functional biological model ventricle. Tissue Engineering. Part A. 14: 215-25. PMID 18333774 DOI: 10.1089/Tea.2007.0351  0.682
2008 Azeloglu EU, Albro MB, Thimmappa VA, Ateshian GA, Costa KD. Heterogeneous transmural proteoglycan distribution provides a mechanism for regulating residual stresses in the aorta. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1197-205. PMID 18156194 DOI: 10.1152/Ajpheart.01027.2007  0.633
2007 Lee WN, Ingrassia CM, Fung-Kee-Fung SD, Costa KD, Holmes JW, Konofagou EE. Theoretical quality assessment of myocardial elastography with in vivo validation. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 54: 2233-45. PMID 18051158 DOI: 10.1109/Tuffc.2007.528  0.518
2007 Elkin BS, Azeloglu EU, Costa KD, Morrison B. Mechanical heterogeneity of the rat hippocampus measured by atomic force microscope indentation. Journal of Neurotrauma. 24: 812-22. PMID 17518536 DOI: 10.1089/Neu.2006.0169  0.648
2007 Cheng RK, Asai T, Tang H, Dashoush NH, Kara RJ, Costa KD, Naka Y, Wu EX, Wolgemuth DJ, Chaudhry HW. Cyclin A2 induces cardiac regeneration after myocardial infarction and prevents heart failure. Circulation Research. 100: 1741-8. PMID 17495221 DOI: 10.1161/Circresaha.107.153544  0.333
2007 Ateshian GA, Costa KD, Hung CT. A theoretical analysis of water transport through chondrocytes Biomechanics and Modeling in Mechanobiology. 6: 91-101. PMID 16705444 DOI: 10.1007/S10237-006-0039-9  0.307
2007 Ingrassia CM, Usyk TP, Kerckhoffs RCP, McCulloch AD, Costa KD, Holmes JW. Model-based development of four-dimensional wall motion measures Computer Methods in Applied Mechanics and Engineering. 196: 3061-3069. DOI: 10.1016/J.Cma.2006.06.016  0.608
2006 Kim do E, Lee EJ, Martens TP, Kara R, Chaudhry HW, Itescu S, Costa KD. Engineered cardiac tissues for in vitro assessment of contractile function and repair mechanisms. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 849-52. PMID 17946863 DOI: 10.1109/IEMBS.2006.259753  0.39
2006 Herz SL, Ingrassia CM, Costa KD, Holmes JW. Model-based screening of wall motion measures for detection of ischemia in three-dimensional cardiac images. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 628-31. PMID 17946412 DOI: 10.1109/IEMBS.2006.260387  0.447
2006 Costa KD. Imaging and probing cell mechanical properties with the atomic force microscope. Methods in Molecular Biology (Clifton, N.J.). 319: 331-61. PMID 16719364 DOI: 10.1007/978-1-59259-993-6_17  0.356
2006 Costa KD, Sim AJ, Yin FC. Non-Hertzian approach to analyzing mechanical properties of endothelial cells probed by atomic force microscopy. Journal of Biomechanical Engineering. 128: 176-84. PMID 16524328 DOI: 10.1115/1.2165690  0.595
2006 Bose K, Ateshian G, Costa K. Atomic force microscopy based technique to measure the viscoelastic response of fibroblasts and chondrocytes using unconfined compression Journal of Biomechanics. 39: S232. DOI: 10.1016/S0021-9290(06)83862-5  0.307
2006 Bose K, Azeloglu E, Lima E, Ateshian G, Costa K. Development of a novel flat punch indentation technique for probing meso-scale mechanical response of soft matter with atomic force microscopy Journal of Biomechanics. 39: S228. DOI: 10.1016/S0021-9290(06)83844-3  0.621
2006 Lee E, Kim D, Costa K. Regional mechanics in an engineered tissue chamber model of myocardial infarction Journal of Biomechanics. 39: S223. DOI: 10.1016/S0021-9290(06)83824-8  0.417
2006 Elkin B, Azeloglu E, Costa K, Morrison B. Local mechanical properties of the rat hippocampus measured by AFM indentation: Potential implications for traumatic brain injury Journal of Biomechanics. 39: S154. DOI: 10.1016/S0021-9290(06)83524-4  0.596
2005 Duan Q, Herz S, Ingrassia C, Costa K, Holmes J, Laine A, Angelini E, Gerard O, Homma S. Dynamic cardiac information from optical flow using four dimensional ultrasound. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 4: 4465-8. PMID 17281228 DOI: 10.1109/IEMBS.2005.1615458  0.461
2005 Takai E, Costa KD, Shaheen A, Hung CT, Guo XE. Osteoblast elastic modulus measured by atomic force microscopy is substrate dependent. Annals of Biomedical Engineering. 33: 963-71. PMID 16060537 DOI: 10.1007/S10439-005-3555-3  0.34
2005 Herz SL, Ingrassia CM, Homma S, Costa KD, Holmes JW. Parameterization of left ventricular wall motion for detection of regional ischemia. Annals of Biomedical Engineering. 33: 912-9. PMID 16060531 DOI: 10.1007/S10439-005-3312-7  0.506
2005 Chao PG, Tang Z, Angelini E, West AC, Costa KD, Hung CT. Dynamic osmotic loading of chondrocytes using a novel microfluidic device. Journal of Biomechanics. 38: 1273-81. PMID 15863112 DOI: 10.1016/J.Jbiomech.2004.06.016  0.318
2005 Ng KW, Wang CC, Mauck RL, Kelly TA, Chahine NO, Costa KD, Ateshian GA, Hung CT. A layered agarose approach to fabricate depth-dependent inhomogeneity in chondrocyte-seeded constructs. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 23: 134-41. PMID 15607885 DOI: 10.1016/J.Orthres.2004.05.015  0.315
2005 Duan Q, Angelini ED, Herz SL, Gerard O, Allain P, Ingrassia CM, Costa KD, Holmes JW, Homma S, Laine AF. Tracking of LV endocardial surface on real-time three-dimensional ultrasound with optical flow Lecture Notes in Computer Science. 3504: 434-445.  0.382
2004 Park S, Costa KD, Ateshian GA. Microscale frictional response of bovine articular cartilage from atomic force microscopy. Journal of Biomechanics. 37: 1679-87. PMID 15388310 DOI: 10.1016/J.Jbiomech.2004.02.017  0.318
2003 Costa KD. Single-cell elastography: probing for disease with the atomic force microscope. Disease Markers. 19: 139-54. PMID 15096710 DOI: 10.1155/2004/482680  0.379
2003 Costa KD, Lee EJ, Holmes JW. Creating alignment and anisotropy in engineered heart tissue: role of boundary conditions in a model three-dimensional culture system. Tissue Engineering. 9: 567-77. PMID 13678436 DOI: 10.1089/107632703768247278  0.611
2002 Costa KD, Hucker WJ, Yin FC. Buckling of actin stress fibers: a new wrinkle in the cytoskeletal tapestry. Cell Motility and the Cytoskeleton. 52: 266-74. PMID 12112140 DOI: 10.1002/Cm.10056  0.58
2002 Takayama Y, Costa KD, Covell JW. Contribution of laminar myofiber architecture to load-dependent changes in mechanics of LV myocardium. American Journal of Physiology. Heart and Circulatory Physiology. 282: H1510-20. PMID 11893589 DOI: 10.1152/Ajpheart.00261.2001  0.357
2002 Thomopoulos S, Knezevic V, Costa KD, Holmes JW. Development of anisotropy in fibroblast populated collagen gels Asme International Mechanical Engineering Congress and Exposition, Proceedings. 253-254. DOI: 10.1115/IMECE2002-32781  0.39
2001 Arts T, Costa KD, Covell JW, McCulloch AD. Relating myocardial laminar architecture to shear strain and muscle fiber orientation American Journal of Physiology - Heart and Circulatory Physiology. 280: H2222-H2229. PMID 11299225 DOI: 10.1152/Ajpheart.2001.280.5.H2222  0.511
2001 Guccione JM, Moonly SM, Moustakidis P, Costa KD, Moulton MJ, Ratcliffe MB, Pasque MK. Mechanism underlying mechanical dysfunction in the border zone of left ventricular aneurysm: a finite element model study. The Annals of Thoracic Surgery. 71: 654-62. PMID 11235723 DOI: 10.1016/S0003-4975(00)02338-9  0.324
2001 Costa KD, Holmes JW, McCulloch AD. Modelling cardiac mechanical properties in three dimensions Philosophical Transactions of the Royal Society a: Mathematical, Physical and Engineering Sciences. 359: 1233-1250. DOI: 10.1098/Rsta.2001.0828  0.566
1999 Costa KD, Yin FC. Analysis of indentation: implications for measuring mechanical properties with atomic force microscopy. Journal of Biomechanical Engineering. 121: 462-71. PMID 10529912 DOI: 10.1115/1.2835074  0.352
1999 Costa KD, Takayama Y, McCulloch AD, Covell JW. Laminar fiber architecture and three-dimensional systolic mechanics in canine ventricular myocardium American Journal of Physiology - Heart and Circulatory Physiology. 276: H595-H607. PMID 9950861 DOI: 10.1152/Ajpheart.1999.276.2.H595  0.539
1997 Costa KD, May-Newman K, Farr D, O'Dell WG, McCulloch AD, Omens JH. Three-dimensional residual strain in midanterior canine left ventricle. American Journal of Physiology. Heart and Circulatory Physiology. 273: H1968-H1976. PMID 29586327 DOI: 10.1152/ajpheart.1997.273.4.H1968  0.69
1996 Costa KD, Hunter PJ, Wayne JS, Waldman LK, Guccione JM, McCulloch AD. A three-dimensional finite element method for large elastic deformations of ventricular myocardium: II--Prolate spheroidal coordinates. Journal of Biomechanical Engineering. 118: 464-72. PMID 8950649 DOI: 10.1115/1.2796032  0.617
1996 Costa KD, Hunter PJ, Rogers JM, Guccione JM, Waldman LK, McCulloch AD. A three-dimensional finite element method for large elastic deformations of ventricular myocardium: I--Cylindrical and spherical polar coordinates. Journal of Biomechanical Engineering. 118: 452-63. PMID 8950648 DOI: 10.1115/1.2796031  0.606
1996 Guccione JM, Costa KD, McCulloch AD. Finite element stress analysis of left ventricular mechanics in the beating dog heart. Journal of Biomechanics. 28: 1167-77. PMID 8550635 DOI: 10.1016/0021-9290(94)00174-3  0.518
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