Steven R. Little - Publications

University of Pittsburgh, Pittsburgh, PA, United States 
chemical engineering, biomedical engineering

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Joseph N, Lawson HD, Overholt KJ, Damodaran K, Gottardi R, Acharya AP, Little SR. Synthesis and characterization of CaSr-Metal Organic Frameworks for biodegradable orthopedic applications. Scientific Reports. 9: 13024. PMID 31506530 DOI: 10.1038/s41598-019-49536-9  1
2019 Bellotti E, Fedorchak MV, Velankar S, Little SR. Tuning of thermoresponsive pNIPAAm hydrogels for the topical retention of controlled release ocular therapeutics. Journal of Materials Chemistry. B. 7: 1276-1283. PMID 30931126 DOI: 10.1039/C8TB02976H  0.56
2018 Nichols DA, Sondh IS, Little SR, Zunino P, Gottardi R. Correction to: Design and validation of an osteochondral bioreactor for the screening of treatments for osteoarthritis. Biomedical Microdevices. 20: 39. PMID 29736756 DOI: 10.1007/s10544-018-0283-7  0.56
2018 Ratay ML, Balmert SC, Bassin EJ, Little SR. Controlled Release of an HDAC Inhibitor for Reduction of Inflammation in Dry Eye Disease. Acta Biomaterialia. PMID 29526828 DOI: 10.1016/j.actbio.2018.03.002  0.72
2018 Fuller TW, Acharya AP, Meyyappan T, Yu M, Bhaskar G, Little SR, Tarin TV. Comparison of Bladder Carcinogens in the Urine of E-cigarette Users Versus Non E-cigarette Using Controls. Scientific Reports. 8: 507. PMID 29323232 DOI: 10.1038/s41598-017-19030-1  1
2017 Ratay ML, Balmert SC, Acharya AP, Greene AC, Meyyappan T, Little SR. TRI Microspheres prevent key signs of dry eye disease in a murine, inflammatory model. Scientific Reports. 7: 17527. PMID 29235530 DOI: 10.1038/s41598-017-17869-y  1
2017 Hwang MP, Ding X, Gao J, Acharya AP, Little SR, Wang Y. A biocompatible betaine-functionalized polycation for coacervation. Soft Matter. PMID 29147712 DOI: 10.1039/c7sm01763d  1
2017 Washington MA, Balmert SC, Fedorchak MV, Little SR, Watkins SC, Meyer TY. Monomer sequence in PLGA microparticles: Effects on acidic microclimates and in vivo inflammatory response. Acta Biomaterialia. PMID 29101019 DOI: 10.1016/j.actbio.2017.10.043  0.72
2017 Ratay ML, Bellotti E, Gottardi R, Little SR. Modern Therapeutic Approaches for Noninfectious Ocular Diseases Involving Inflammation. Advanced Healthcare Materials. PMID 29034584 DOI: 10.1002/adhm.201700733  0.72
2017 Acharya AP, Theisen KM, Correa A, Meyyappan T, Apfel A, Sun T, Tarin TV, Little SR. An Inexpensive, Point-of-Care Urine Test for Bladder Cancer in Patients Undergoing Hematuria Evaluation. Advanced Healthcare Materials. PMID 28885787 DOI: 10.1002/adhm.201700808  1
2017 Fedorchak MV, Conner IP, Schuman JS, Cugini A, Little SR. Long Term Glaucoma Drug Delivery Using a Topically Retained Gel/Microsphere Eye Drop. Scientific Reports. 7: 8639. PMID 28819134 DOI: 10.1038/s41598-017-09379-8  0.44
2017 Balmert SC, Donahue C, Vu JR, Erdos G, Falo LD, Little SR. In vivo induction of regulatory T cells promotes allergen tolerance and suppresses allergic contact dermatitis. Journal of Controlled Release : Official Journal of the Controlled Release Society. 261: 223-233. PMID 28694031 DOI: 10.1016/j.jconrel.2017.07.006  0.72
2017 Bayer EA, Jordan J, Gottardi R, Fedorchak M, Kumta PN, Little S. Programmed Platelet Derived Growth Factor-ββ and Bone Morphogenetic Protein-2 Delivery from a Hybrid Calcium Phosphate/Alginate Scaffold. Tissue Engineering. Part A. PMID 28537482 DOI: 10.1089/ten.TEA.2017.0027  0.56
2017 Ratay ML, Glowacki AJ, Balmert SC, Acharya AP, Polat J, Andrews LP, Fedorchak MV, Schuman JS, Vignali DAA, Little SR. Treg-recruiting microspheres prevent inflammation in a murine model of dry eye disease. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 28501670 DOI: 10.1016/j.jconrel.2017.05.007  1
2016 Washington MA, Swiner DJ, Bell KR, Fedorchak MV, Little SR, Meyer TY. The impact of monomer sequence and stereochemistry on the swelling and erosion of biodegradable poly(lactic-co-glycolic acid) matrices. Biomaterials. 117: 66-76. PMID 27936418 DOI: 10.1016/j.biomaterials.2016.11.037  0.44
2016 Bayer EA, Fedorchak MV, Little SR. The Influence of Platelet-Derived Growth Factor and Bone Morphogenetic Protein Presentation on Tubule Organization by Human Umbilical Vascular Endothelial Cells and Human Mesenchymal Stem Cells in Coculture. Tissue Engineering. Part A. 22: 1296-1304. PMID 27650131 DOI: 10.1089/ten.TEA.2016.0163  0.44
2016 Francisconi CF, Vieira AE, Biguetti CC, Glowacki AJ, Trombone AP, Letra A, Menezes Silva R, Sfeir CS, Little SR, Garlet GP. Characterization of the Protective Role of Regulatory T Cells in Experimental Periapical Lesion Development and Their Chemoattraction Manipulation as a Therapeutic Tool. Journal of Endodontics. 42: 120-6. PMID 26589811 DOI: 10.1016/j.joen.2015.09.022  0.4
2015 Guaragno ML, Gottardi R, Fedorchak MV, Roy A, Kumta PN, Little SR. One-step synthesis of fluorescently labelled, single-walled carbon nanotubes. Chemical Communications (Cambridge, England). PMID 26458421 DOI: 10.1039/c5cc05573c  1
2015 Acharya AP, Little SR. Stapled endosome disrupting alginate particles for cytosolic delivery of cations. Journal of Drug Targeting. 23: 690-7. PMID 26453164 DOI: 10.3109/1061186X.2015.1048517  1
2015 Balmert SC, Zmolek AC, Glowacki AJ, Knab TD, Rothstein SN, Wokpetah JM, Fedorchak MV, Little SR. Positive Charge of "Sticky" Peptides and Proteins Impedes Release From Negatively Charged PLGA Matrices. Journal of Materials Chemistry. B, Materials For Biology and Medicine. 3: 4723-4734. PMID 26085928 DOI: 10.1039/C5TB00515A  1
2015 Knab TD, Little SR, Parker RS. A systems approach to modeling drug release from polymer microspheres to accelerate in vitro to in vivo translation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 211: 74-84. PMID 26003043 DOI: 10.1016/j.jconrel.2015.04.045  1
2015 Fisher JD, Acharya AP, Little SR. Micro and nanoparticle drug delivery systems for preventing allotransplant rejection. Clinical Immunology (Orlando, Fla.). PMID 25937032 DOI: 10.1016/j.clim.2015.04.013  1
2015 Lash MH, Jordan JC, Blevins LC, Fedorchak MV, Little SR, McCarthy JJ. Non-brownian particle-based materials with microscale and nanoscale hierarchy. Angewandte Chemie (International Ed. in English). 54: 5854-8. PMID 25892480 DOI: 10.1002/anie.201500273  1
2015 Glowacki AJ, Gottardi R, Yoshizawa S, Cavalla F, Garlet GP, Sfeir C, Little SR. Strategies to direct the enrichment, expansion, and recruitment of regulatory cells for the treatment of disease. Annals of Biomedical Engineering. 43: 593-602. PMID 25245220 DOI: 10.1007/s10439-014-1125-2  1
2015 Lash MH, Fedorchak MV, Little SR, McCarthy JJ. Fabrication and characterization of non-Brownian particle-based crystals. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 898-905. PMID 24983125 DOI: 10.1021/la501511s  1
2014 Fu HL, Hong Y, Little SR, Wagner WR. Collagenase-labile polyurethane urea synthesis and processing into hollow fiber membranes. Biomacromolecules. 15: 2924-32. PMID 25003560 DOI: 10.1021/bm500552f  1
2014 Fedorchak MV, Conner IP, Medina CA, Wingard JB, Schuman JS, Little SR. 28-day intraocular pressure reduction with a single dose of brimonidine tartrate-loaded microspheres. Experimental Eye Research. 125: 210-6. PMID 24983144 DOI: 10.1016/j.exer.2014.06.013  0.44
2014 Rothstein SN, Huber KD, Sluis-Cremer N, Little SR. In vitro characterization of a sustained-release formulation for enfuvirtide. Antimicrobial Agents and Chemotherapy. 58: 1797-9. PMID 24366751 DOI: 10.1128/AAC.02440-13  1
2013 Glowacki AJ, Yoshizawa S, Jhunjhunwala S, Vieira AE, Garlet GP, Sfeir C, Little SR. Prevention of inflammation-mediated bone loss in murine and canine periodontal disease via recruitment of regulatory lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 110: 18525-30. PMID 24167272 DOI: 10.1073/pnas.1302829110  0.96
2013 Kamalasanan K, Gottardi R, Tan S, Chen Y, Godugu B, Rothstein S, Balazs AC, Star A, Little SR. "Zero-dimensional" single-walled carbon nanotubes. Angewandte Chemie (International Ed. in English). 52: 11308-12. PMID 24038731 DOI: 10.1002/anie.201305526  1
2013 Jhunjhunwala S, Chen LC, Nichols EE, Thomson AW, Raimondi G, Little SR. All-trans retinoic acid and rapamycin synergize with transforming growth factor-β1 to induce regulatory T cells but confer different migratory capacities. Journal of Leukocyte Biology. 94: 981-9. PMID 23898044 DOI: 10.1189/jlb.0312167  0.96
2012 Rothstein SN, Kay JE, Schopfer FJ, Freeman BA, Little SR. A retrospective mathematical analysis of controlled release design and experimentation. Molecular Pharmaceutics. 9: 3003-11. PMID 23009671 DOI: 10.1021/mp300388w  1
2012 Li J, Rothstein SN, Little SR, Edenborn HM, Meyer TY. The effect of monomer order on the hydrolysis of biodegradable poly(lactic-co-glycolic acid) repeating sequence copolymers. Journal of the American Chemical Society. 134: 16352-9. PMID 22950719 DOI: 10.1021/ja306866w  1
2012 Jhunjhunwala S, Raimondi G, Glowacki AJ, Hall SJ, Maskarinec D, Thorne SH, Thomson AW, Little SR. Bioinspired controlled release of CCL22 recruits regulatory T cells in vivo. Advanced Materials (Deerfield Beach, Fla.). 24: 4735-8. PMID 22821823 DOI: 10.1002/adma.201202513  0.96
2012 Eghtesad S, Jhunjhunwala S, Little SR, Clemens PR. Effect of rapamycin on immunity induced by vector-mediated dystrophin expression in mdx skeletal muscle. Scientific Reports. 2: 399. PMID 22570764 DOI: 10.1038/srep00399  0.96
2012 Balmert SC, Little SR. Biomimetic delivery with micro- and nanoparticles. Advanced Materials (Deerfield Beach, Fla.). 24: 3757-78. PMID 22528985 DOI: 10.1002/adma.201200224  0.72
2012 Jhunjhunwala S, Balmert SC, Raimondi G, Dons E, Nichols EE, Thomson AW, Little SR. Controlled release formulations of IL-2, TGF-β1 and rapamycin for the induction of regulatory T cells. Journal of Controlled Release : Official Journal of the Controlled Release Society. 159: 78-84. PMID 22285546 DOI: 10.1016/j.jconrel.2012.01.013  0.96
2012 Tengood JE, Maskarinec D, Ridenour R, Little SR. A mathematical model for release of biologics from porous hollow fibers. Journal of Biomedical Materials Research. Part A. 100: 817-26. PMID 22275332 DOI: 10.1002/jbm.a.34013  0.84
2011 Kamalasanan K, Jhunjhunwala S, Wu J, Swanson A, Gao D, Little SR. Patchy, anisotropic microspheres with soft protein islets. Angewandte Chemie (International Ed. in English). 50: 8706-8. PMID 21809425 DOI: 10.1002/anie.201101217  0.96
2011 Jhunjhunwala S, Little SR. Microparticulate systems for targeted drug delivery to phagocytes. Cell Cycle (Georgetown, Tex.). 10: 2047-8. PMID 21623160 DOI: 10.4161/cc.10.13.15713  0.96
2011 Eghtesad S, Jhunjhunwala S, Little SR, Clemens PR. Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle. Molecular Medicine (Cambridge, Mass.). 17: 917-24. PMID 21607286 DOI: 10.2119/molmed.2010.00256  0.96
2011 Dutt M, Kuksenok O, Nayhouse MJ, Little SR, Balazs AC. Modeling the self-assembly of lipids and nanotubes in solution: forming vesicles and bicelles with transmembrane nanotube channels. Acs Nano. 5: 4769-82. PMID 21604769 DOI: 10.1021/nn201260r  1
2011 Tengood JE, Ridenour R, Brodsky R, Russell AJ, Little SR. Sequential delivery of basic fibroblast growth factor and platelet-derived growth factor for angiogenesis. Tissue Engineering. Part A. 17: 1181-9. PMID 21142700 DOI: 10.1089/ten.TEA.2010.0551  0.84
2011 Dutt M, Kuksenok O, Little SR, Balazs AC. Forming transmembrane channels using end-functionalized nanotubes. Nanoscale. 3: 240-50. PMID 20976358 DOI: 10.1039/c0nr00578a  1
2010 Tengood JE, Kovach KM, Vescovi PE, Russell AJ, Little SR. Sequential delivery of vascular endothelial growth factor and sphingosine 1-phosphate for angiogenesis. Biomaterials. 31: 7805-12. PMID 20674008 DOI: 10.1016/j.biomaterials.2010.07.010  0.84
2010 Kokai LE, Tan H, Jhunjhunwala S, Little SR, Frank JW, Marra KG. Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double-walled microspheres. Journal of Controlled Release : Official Journal of the Controlled Release Society. 141: 168-76. PMID 19751780 DOI: 10.1016/j.jconrel.2009.09.003  0.96
2009 Rothstein SN, Federspiel WJ, Little SR. A unified mathematical model for the prediction of controlled release from surface and bulk eroding polymer matrices. Biomaterials. 30: 1657-64. PMID 19101031 DOI: 10.1016/j.biomaterials.2008.12.002  1
2007 Choleris E, Little SR, Mong JA, Puram SV, Langer R, Pfaff DW. Microparticle-based delivery of oxytocin receptor antisense DNA in the medial amygdala blocks social recognition in female mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 4670-5. PMID 17360582 DOI: 10.1073/pnas.0700670104  0.92
2006 Zugates GT, Anderson DG, Little SR, Lawhorn IE, Langer R. Synthesis of poly(beta-amino ester)s with thiol-reactive side chains for DNA delivery. Journal of the American Chemical Society. 128: 12726-34. PMID 17002366 DOI: 10.1021/ja061570n  0.92
2005 Little SR, Langer R. Nonviral delivery of cancer genetic vaccines. Advances in Biochemical Engineering/Biotechnology. 99: 93-118. PMID 16568889  0.92
2005 Wood KC, Little SR, Langer R, Hammond PT. A family of hierarchically self-assembling linear-dendritic hybrid polymers for highly efficient targeted gene delivery. Angewandte Chemie (International Ed. in English). 44: 6704-8. PMID 16173106 DOI: 10.1002/anie.200502152  1
2005 Little SR, Lynn DM, Puram SV, Langer R. Formulation and characterization of poly (beta amino ester) microparticles for genetic vaccine delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 107: 449-62. PMID 16112767 DOI: 10.1016/j.jconrel.2005.04.022  1
2004 Haining WN, Anderson DG, Little SR, von Bergwelt-Baildon MS, Cardoso AA, Alves P, Kosmatopoulos K, Nadler LM, Langer R, Kohane DS, von Berwelt-Baildon MS. pH-triggered microparticles for peptide vaccination. Journal of Immunology (Baltimore, Md. : 1950). 173: 2578-85. PMID 15294974  1
2004 Little SR, Lynn DM, Ge Q, Anderson DG, Puram SV, Chen J, Eisen HN, Langer R. Poly-beta amino ester-containing microparticles enhance the activity of nonviral genetic vaccines. Proceedings of the National Academy of Sciences of the United States of America. 101: 9534-9. PMID 15210954 DOI: 10.1073/pnas.0403549101  1
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