Year |
Citation |
Score |
2020 |
Ye J. Transcription factors activated through RIP (Regulated Intramembrane Proteolysis) and RAT (Regulated Alternative Translocation)). The Journal of Biological Chemistry. PMID 32487748 DOI: 10.1074/Jbc.Rev120.012669 |
0.42 |
|
2019 |
Kim J, Thompson B, Han S, Lotan Y, McDonald JG, Ye J. Uptake of HDL-cholesterol contributes to lipid accumulation in clear cell renal cell carcinoma. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 158525. PMID 31513923 DOI: 10.1016/J.Bbalip.2019.158525 |
0.323 |
|
2019 |
Wang J, Kinch LN, Denard B, Lee CE, Esmaeilzadeh Gharehdaghi E, Grishin N, Ye J. Identification of residues critical for topology inversion of the transmembrane protein TM4SF20 through regulated alternative translocation. The Journal of Biological Chemistry. PMID 30808712 DOI: 10.1074/Jbc.Ra119.007681 |
0.314 |
|
2018 |
DeBose-Boyd RA, Ye J. SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond. Trends in Biochemical Sciences. PMID 29500098 DOI: 10.1016/J.Tibs.2018.01.005 |
0.389 |
|
2016 |
Chen Q, Denard B, Lee CE, Han S, Ye JS, Ye J. Inverting the Topology of a Transmembrane Protein by Regulating the Translocation of the First Transmembrane Helix. Molecular Cell. PMID 27499293 DOI: 10.1016/J.Molcel.2016.06.032 |
0.395 |
|
2015 |
Denard B, Pavia-Jimenez A, Chen W, Williams NS, Naina H, Collins R, Brugarolas J, Ye J. Identification of CREB3L1 as a Biomarker Predicting Doxorubicin Treatment Outcome. Plos One. 10: e0129233. PMID 26110425 DOI: 10.1371/Journal.Pone.0129233 |
0.322 |
|
2014 |
Chen Q, Lee CE, Denard B, Ye J. Sustained Induction of Collagen Synthesis by TGF-β Requires Regulated Intramembrane Proteolysis of CREB3L1 Plos One. 9. PMID 25310401 DOI: 10.1371/Journal.Pone.0108528 |
0.346 |
|
2014 |
Kim H, Ye J. Cellular responses to excess fatty acids: focus on ubiquitin regulatory X domain-containing protein 8. Current Opinion in Lipidology. 25: 118-124. PMID 24378746 DOI: 10.1097/Mol.0000000000000048 |
0.35 |
|
2013 |
Ye J. Roles of regulated intramembrane proteolysis in virus infection and antiviral immunity Biochimica Et Biophysica Acta - Biomembranes. 1828: 2926-2932. PMID 24099010 DOI: 10.1016/J.Bbamem.2013.05.005 |
0.339 |
|
2013 |
Deng Y, Wang ZV, Tao C, Gao N, Holland WL, Ferdous A, Repa JJ, Liang G, Ye J, Lehrman MA, Hill JA, Horton JD, Scherer PE. The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism. The Journal of Clinical Investigation. 123: 455-68. PMID 23257357 DOI: 10.1172/Jci62819 |
0.332 |
|
2013 |
Chen Q, Denard B, Huang H, Ye J. Epigenetic silencing of antiviral genes renders clones of Huh-7 cells permissive for hepatitis C virus replication Journal of Virology. 87: 659-665. PMID 23115279 DOI: 10.1128/Jvi.01984-12 |
0.336 |
|
2012 |
Denard B, Lee C, Ye J. Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. Elife. 1: e00090. PMID 23256041 DOI: 10.7554/Elife.00090 |
0.333 |
|
2012 |
Ye J. Hepatitis C virus: A new class of virus associated with particles derived from very low-density lipoproteins Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1099-1103. PMID 22517369 DOI: 10.1161/Atvbaha.111.241448 |
0.31 |
|
2012 |
Ye J. Cellular responses to unsaturated fatty acids mediated by their sensor Ubxd8 Frontiers in Biology. 7: 397-403. DOI: 10.1007/S11515-012-1247-6 |
0.323 |
|
2011 |
Denard B, Seemann J, Chen Q, Gay A, Huang H, Chen Y, Ye J. The membrane-bound transcription factor CREB3L1 is activated in response to virus infection to inhibit proliferation of virus-infected cells. Cell Host & Microbe. 10: 65-74. PMID 21767813 DOI: 10.1016/J.Chom.2011.06.006 |
0.353 |
|
2011 |
Ye J. Cell biology. Protease sets site-1 on lysosomes. Science (New York, N.Y.). 333: 50-1. PMID 21719668 DOI: 10.1126/Science.1209417 |
0.383 |
|
2011 |
Ye J, DeBose-Boyd RA. Regulation of cholesterol and fatty acid synthesis. Cold Spring Harbor Perspectives in Biology. 3. PMID 21504873 DOI: 10.1101/Cshperspect.A004754 |
0.43 |
|
2010 |
Lee JN, Kim H, Yao H, Chen Y, Weng K, Ye J. Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 21424-9. PMID 21115839 DOI: 10.1073/Pnas.1011859107 |
0.323 |
|
2010 |
Brown MS, Ye J, Goldstein JL. Medicine. HDL miR-ed down by SREBP introns. Science (New York, N.Y.). 328: 1495-6. PMID 20558698 DOI: 10.1126/Science.1192409 |
0.541 |
|
2009 |
Ikeda Y, Demartino GN, Brown MS, Lee JN, Goldstein JL, Ye J. Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes. The Journal of Biological Chemistry. 284: 34889-900. PMID 19815544 DOI: 10.1074/Jbc.M109.044875 |
0.593 |
|
2009 |
Owen DM, Huang H, Ye J, Gale M. Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor. Virology. 394: 99-108. PMID 19751943 DOI: 10.1016/J.Virol.2009.08.037 |
0.316 |
|
2008 |
Lee JN, Zhang X, Feramisco JD, Gong Y, Ye J. Unsaturated fatty acids inhibit proteasomal degradation of Insig-1 at a postubiquitination step. The Journal of Biological Chemistry. 283: 33772-83. PMID 18835813 DOI: 10.1074/Jbc.M806108200 |
0.402 |
|
2008 |
Yao H, Ye J. Long Chain Acyl-CoA Synthetase 3-mediated Phosphatidylcholine Synthesis Is Required for Assembly of Very Low Density Lipoproteins in Human Hepatoma Huh7 Cells Journal of Biological Chemistry. 283: 849-854. PMID 18003621 DOI: 10.1074/Jbc.M706160200 |
0.391 |
|
2007 |
Huang H, Chen Y, Ye J. Inhibition of hepatitis C virus replication by peroxidation of arachidonate and restoration by vitamin E. Proceedings of the National Academy of Sciences of the United States of America. 104: 18666-70. PMID 18003907 DOI: 10.1073/Pnas.0708423104 |
0.341 |
|
2007 |
Ye J. Reliance of host cholesterol metabolic pathways for the life cycle of hepatitis C virus Plos Pathogens. 3. PMID 17784784 DOI: 10.1371/Journal.Ppat.0030108 |
0.335 |
|
2007 |
Huang H, Sun F, Owen DM, Li W, Chen Y, Gale M, Ye J. Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proceedings of the National Academy of Sciences of the United States of America. 104: 5848-53. PMID 17376867 DOI: 10.1073/Pnas.0700760104 |
0.348 |
|
2006 |
Lee JN, Song B, DeBose-Boyd RA, Ye J. Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78. The Journal of Biological Chemistry. 281: 39308-15. PMID 17043353 DOI: 10.1074/Jbc.M608999200 |
0.424 |
|
2006 |
Gong Y, Lee JN, Brown MS, Goldstein JL, Ye J. Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 6154-9. PMID 16606821 DOI: 10.1073/Pnas.0601923103 |
0.604 |
|
2006 |
Lee JN, Gong Y, Zhang X, Ye J. Proteasomal degradation of ubiquitinated Insig proteins is determined by serine residues flanking ubiquitinated lysines. Proceedings of the National Academy of Sciences of the United States of America. 103: 4958-63. PMID 16549805 DOI: 10.1073/Pnas.0600422103 |
0.362 |
|
2006 |
Gong Y, Lee JN, Lee PC, Goldstein JL, Brown MS, Ye J. Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake. Cell Metabolism. 3: 15-24. PMID 16399501 DOI: 10.1016/J.Cmet.2005.11.014 |
0.59 |
|
2005 |
Wang C, Gale M, Keller BC, Huang H, Brown MS, Goldstein JL, Ye J. Identification of FBL2 as a geranylgeranylated cellular protein required for hepatitis C virus RNA replication. Molecular Cell. 18: 425-34. PMID 15893726 DOI: 10.1016/J.Molcel.2005.04.004 |
0.547 |
|
2004 |
Lee JN, Ye J. Proteolytic activation of sterol regulatory element-binding protein induced by cellular stress through depletion of Insig-1. The Journal of Biological Chemistry. 279: 45257-65. PMID 15304479 DOI: 10.1074/Jbc.M408235200 |
0.394 |
|
2003 |
Ye J, Wang C, Sumpter R, Brown MS, Goldstein JL, Gale M. Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation. Proceedings of the National Academy of Sciences of the United States of America. 100: 15865-70. PMID 14668447 DOI: 10.1073/Pnas.2237238100 |
0.55 |
|
2000 |
Ye J, Rawson RB, Komuro R, Chen X, Davé UP, Prywes R, Brown MS, Goldstein JL. ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Molecular Cell. 6: 1355-64. PMID 11163209 DOI: 10.1016/S1097-2765(00)00133-7 |
0.562 |
|
2000 |
Ye J, Davé UP, Grishin NV, Goldstein JL, Brown MS. Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease. Proceedings of the National Academy of Sciences of the United States of America. 97: 5123-8. PMID 10805775 DOI: 10.1073/Pnas.97.10.5123 |
0.559 |
|
2000 |
Brown MS, Ye J, Rawson RB, Goldstein JL. Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans. Cell. 100: 391-8. PMID 10693756 DOI: 10.1016/S0092-8674(00)80675-3 |
0.493 |
|
1997 |
Rawson RB, Zelenski NG, Nijhawan D, Ye J, Sakai J, Hasan MT, Chang TY, Brown MS, Goldstein JL. Complementation cloning of S2P, a gene encoding a putative metalloprotease required for intramembrane cleavage of SREBPs. Molecular Cell. 1: 47-57. PMID 9659902 DOI: 10.1016/S1097-2765(00)80006-4 |
0.584 |
|
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