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Matthew D. Lew, Ph.D. - Publications

Affiliations: 
2015- Electrical and Systems Engineering Washington University, Saint Louis, St. Louis, MO 
Area:
super-resolution microscopy, single-molecule spectroscopy, optimal imaging system design, nanoscale sensing
Website:
https://lewlab.wustl.edu
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65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhou W, O'Neill CL, Ding T, Zhang O, Rudra JS, Lew MD. Resolving the nanoscale structure of β-sheet assemblies using single-molecule orientation-localization microscopy. Biorxiv : the Preprint Server For Biology. PMID 37745382 DOI: 10.1101/2023.09.13.557571  0.781
2023 Wu T, King MR, Farag M, Pappu RV, Lew MD. Single fluorogen imaging reveals spatial inhomogeneities within biomolecular condensates. Biorxiv : the Preprint Server For Biology. PMID 36747818 DOI: 10.1101/2023.01.26.525727  0.675
2022 Zhang O, Guo Z, He Y, Wu T, Vahey MD, Lew MD. Six-Dimensional Single-Molecule Imaging with Isotropic Resolution using a Multi-View Reflector Microscope. Nature Photonics. 17: 179-186. PMID 36968242 DOI: 10.1038/s41566-022-01116-6  0.85
2022 Jusuf JM, Lew MD. Towards optimal point spread function design for resolving closely spaced emitters in three dimensions. Optics Express. 30: 37154-37174. PMID 36258632 DOI: 10.1364/OE.472067  0.445
2022 Wu T, Lu P, Rahman MA, Li X, Lew MD. Deep-SMOLM: deep learning resolves the 3D orientations and 2D positions of overlapping single molecules with optimal nanoscale resolution. Optics Express. 30: 36761-36773. PMID 36258598 DOI: 10.1364/OE.470146  0.698
2022 Shen M, Ding T, Tan C, Rackers WH, Zhang D, Lew MD, Sadtler B. Imaging of Catalytic Reactions on Tungsten Oxide Nanowires Connects Surface-Ligand Redox Chemistry with Photocatalytic Activity. Nano Letters. 22: 4694-4701. PMID 35674669 DOI: 10.1021/acs.nanolett.2c00674  0.776
2022 Wu T, Lu J, Lew MD. Dipole-spread-function engineering for simultaneously measuring the 3D orientations and 3D positions of fluorescent molecules. Optica. 9: 505-511. PMID 35601691 DOI: 10.1364/OPTICA.451899  0.791
2022 Biteen JS, Lew MD, Willets KA. Tribute to W. E. Moerner. The Journal of Physical Chemistry. B. 126: 1157-1158. PMID 35172582 DOI: 10.1021/acs.jpcb.2c00136  0.682
2022 Zhang O, Zhou W, Lu J, Wu T, Lew MD. Resolving the Three-Dimensional Rotational and Translational Dynamics of Single Molecules Using Radially and Azimuthally Polarized Fluorescence. Nano Letters. 22: 1024-1031. PMID 35073487 DOI: 10.1021/acs.nanolett.1c03948  0.829
2021 Ding T, Lew MD. Single-Molecule Localization Microscopy of 3D Orientation and Anisotropic Wobble Using a Polarized Vortex Point Spread Function. The Journal of Physical Chemistry. B. PMID 34766758 DOI: 10.1021/acs.jpcb.1c08073  0.858
2021 Shen M, Ding T, Rackers WH, Tan C, Mahmood K, Lew MD, Sadtler B. Single-Molecule Colocalization of Redox Reactions on Semiconductor Photocatalysts Connects Surface Heterogeneity and Charge-Carrier Separation in Bismuth Oxybromide. Journal of the American Chemical Society. PMID 34284584 DOI: 10.1021/jacs.1c02377  0.784
2021 Zhang O, Lew MD. Single-molecule orientation localization microscopy II: a performance comparison. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 38: 288-297. PMID 33690542 DOI: 10.1364/JOSAA.411983  0.839
2021 Zhang O, Lew MD. Single-molecule orientation localization microscopy I: fundamental limits. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 38: 277-287. PMID 33690541 DOI: 10.1364/JOSAA.411981  0.833
2020 Mazidi H, Ding T, Nehorai A, Lew MD. Quantifying accuracy and heterogeneity in single-molecule super-resolution microscopy. Nature Communications. 11: 6353. PMID 33311471 DOI: 10.1038/s41467-020-20056-9  0.791
2020 Zhang O, Lew MD. Quantum limits for precisely estimating the orientation and wobble of dipole emitters. Physical Review Research. 2. PMID 32832916 DOI: 10.1103/Physrevresearch.2.033114  0.825
2020 Ding T, Wu T, Mazidi H, Zhang O, Lew MD. Single-molecule orientation localization microscopy for resolving structural heterogeneities between amyloid fibrils. Optica. 7: 602-607. PMID 32832582 DOI: 10.1364/optica.388157  0.777
2020 Lu J, Mazidi H, Ding T, Zhang O, Lew MD. Single-molecule 3D orientation imaging reveals nanoscale compositional heterogeneity in lipid membranes. Angewandte Chemie (International Ed. in English). PMID 32648275 DOI: 10.1002/Anie.202006207  0.764
2020 Shen M, Ding T, Luo J, Tan C, Mahmood K, Wang Z, Zhang D, Mishra R, Lew MD, Sadtler B. Competing Activation and Deactivation Mechanisms in Photodoped Bismuth Oxybromide Nanoplates Probed by Single-Molecule Fluorescence Imaging. The Journal of Physical Chemistry Letters. PMID 32516535 DOI: 10.1021/Acs.Jpclett.0C01237  0.787
2020 Shen M, Ding T, Hartman ST, Wang F, Krucylak C, Wang Z, Tan C, Yin B, Mishra R, Lew MD, Sadtler B. Nanoscale Colocalization of Fluorogenic Probes Reveals the Role of Oxygen Vacancies in the Photocatalytic Activity of Tungsten Oxide Nanowires Acs Catalysis. 10: 2088-2099. DOI: 10.1021/Acscatal.9B04481  0.353
2020 Ding T, Wu T, Mazidi H, Zhang O, Lew MD. Enhanced Transient Amyloid Binding Microscopy using Single-Molecule Orientation Measurements Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.936  0.551
2020 Lu J, Mazidi H, Ding T, Zhang O, Lew MD. Superresolution 3D Orientation Imaging Reveals Nanoscale Compositional Heterogeneity in Lipid Membranes Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.294  0.496
2020 Lu J, Mazidi H, Ding T, Zhang O, Lew MD. Back Cover: Single‐Molecule 3D Orientation Imaging Reveals Nanoscale Compositional Heterogeneity in Lipid Membranes (Angew. Chem. Int. Ed. 40/2020) Angewandte Chemie. 59: 17760-17760. DOI: 10.1002/Anie.202011444  0.494
2020 Lu J, Mazidi H, Ding T, Zhang O, Lew MD. Rücktitelbild: Single‐Molecule 3D Orientation Imaging Reveals Nanoscale Compositional Heterogeneity in Lipid Membranes (Angew. Chem. 40/2020) Angewandte Chemie. 132: 17912-17912. DOI: 10.1002/ange.202011444  0.413
2019 Zhang O, Lew MD. Fundamental Limits on Measuring the Rotational Constraint of Single Molecules Using Fluorescence Microscopy. Physical Review Letters. 122: 198301. PMID 31144939 DOI: 10.1103/Physrevlett.122.198301  0.831
2019 Zhang O, Lu J, Ding T, Lew MD. Erratum: "Imaging the three-dimensional orientation and rotational mobility of fluorescent emitters using the Tri-spot point spread function" [Appl. Phys. Lett. 113, 031103 (2018)] Applied Physics Letters. 115: 69901. DOI: 10.1063/1.5111616  0.531
2018 Maji D, Lu J, Sarder P, Schmieder AH, Cui G, Yang X, Pan D, Lew MD, Achilefu S, Lanza GM. Cellular Trafficking of Sn-2 Phosphatidylcholine Prodrugs Studied with Fluorescence Lifetime Imaging and Super-resolution Microscopy. Precision Nanomedicine. 1: 128-145. PMID 31249994 DOI: 10.33218/prnano1(2).180724.1  0.712
2018 Mazidi H, Lu J, Nehorai A, Lew MD. Minimizing Structural Bias in Single-Molecule Super-Resolution Microscopy. Scientific Reports. 8: 13133. PMID 30177692 DOI: 10.1038/S41598-018-31366-W  0.82
2018 Zhang O, Lu J, Ding T, Lew MD. Imaging the three-dimensional orientation and rotational mobility of fluorescent emitters using the Tri-spot point spread function. Applied Physics Letters. 113: 031103. PMID 30057423 DOI: 10.1063/1.5031759  0.803
2018 Spehar K, Ding T, Sun Y, Kedia N, Lu J, Nahass GR, Lew MD, Bieschke J. Super-Resolution Imaging of Amyloid Structures over Extended Times Using Transient Binding of Single Thioflavin T Molecules. Chembiochem : a European Journal of Chemical Biology. PMID 29953718 DOI: 10.1016/J.Bpj.2018.11.2471  0.806
2018 Spehar K, Ding T, Sun Y, Lu J, Nahass GR, Lew MD, Bieschke J. Long-Term Super-Resolution Imaging of Amyloid Structures using Transient Binding of Standard Amyloid Probes Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1934  0.476
2018 Spehar K, Ding T, Sun Y, Kedia N, Lu J, Nahass GR, Lew MD, Bieschke J. Cover Feature: Super-resolution Imaging of Amyloid Structures over Extended Times by Using Transient Binding of Single Thioflavin T Molecules (ChemBioChem 18/2018) Chembiochem. 19: 1897-1897. DOI: 10.1002/Cbic.201800489  0.533
2017 Liba O, Lew MD, SoRelle ED, Dutta R, Sen D, Moshfeghi DM, Chu S, de la Zerda A. Erratum: Speckle-modulating optical coherence tomography in living mice and humans. Nature Communications. 8: 16131. PMID 28695909 DOI: 10.1038/ncomms16131  0.751
2017 Liba O, Lew MD, SoRelle ED, Dutta R, Sen D, Moshfeghi DM, Chu S, de la Zerda A. Speckle-modulating optical coherence tomography in living mice and humans. Nature Communications. 8: 15845. PMID 28632205 DOI: 10.1038/Ncomms15845  0.783
2016 Lee M, Lew M, Diezmann Av, Weiss L, Shechtman Y, Moerner W. 3D Single-Molecule Super-Resolution Fluorescence Microscopy with the Corkscrew Point Spread Function Biophysical Journal. 110: 176a. DOI: 10.1016/J.Bpj.2015.11.980  0.824
2015 von Diezmann A, Lee MY, Lew MD, Moerner WE. Correcting field-dependent aberrations with nanoscale accuracy in three-dimensional single-molecule localization microscopy. Optica. 2: 985-993. PMID 26973863 DOI: 10.1364/OPTICA.2.000985  0.676
2015 von Diezmann A, Lee MY, Lew MD, Moerner WE. Correcting field-dependent aberrations with nanoscale accuracy in three-dimensional single-molecule localization microscopy Optica. 2: 985-993. DOI: 10.1364/OPTICA.2.000985  0.614
2015 Lew MD. Accurate 3D Nanoscale Imaging of Dipole-like Emitters Frontiers in Optics. DOI: 10.1364/Ls.2015.Lw3I.2  0.579
2015 Lew MD, Moerner WE. An azimuthal polarizer assures localization accuracy in single-molecule super-resolution fluorescence microscopy Cleo: Science and Innovations, Cleo-Si 2015. 2267. DOI: 10.1364/CLEO_SI.2015.STh4K.2  0.65
2014 Lew MD, Moerner WE. Azimuthal polarization filtering for accurate, precise, and robust single-molecule localization microscopy. Nano Letters. 14: 6407-13. PMID 25272093 DOI: 10.1021/Nl502914K  0.69
2014 Backlund MP, Lew MD, Backer AS, Sahl SJ, Moerner WE. The role of molecular dipole orientation in single-molecule fluorescence microscopy and implications for super-resolution imaging. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 15: 587-99. PMID 24382708 DOI: 10.1002/Cphc.201300880  0.859
2014 Lew MD, Nikolaitchik OA, Hu W, Moerner W. Precise Measurement of the Relative Position of RNA Dimers within Virus-Like Particles using 2-Color 3D Super-Resolution Fluorescence Microscopy Biophysical Journal. 106: 399a. DOI: 10.1016/J.Bpj.2013.11.2252  0.595
2013 Lew MD, von Diezmann AR, Moerner WE. Easy-DHPSF open-source software for three-dimensional localization of single molecules with precision beyond the optical diffraction limit. Protocol Exchange. 2013. PMID 25279136 DOI: 10.1038/protex.2013.026  0.676
2013 Backlund MP, Lew MD, Backer AS, Sahl SJ, Grover G, Agrawal A, Piestun R, Moerner WE. The double-helix point spread function enables precise and accurate measurement of 3D single-molecule localization and orientation. Proceedings of Spie--the International Society For Optical Engineering. 8590: 85900. PMID 24817798 DOI: 10.1117/12.2001671  0.854
2013 Backer AS, Backlund MP, Lew MD, Moerner WE. Single-molecule orientation measurements with a quadrated pupil. Optics Letters. 38: 1521-3. PMID 23632538 DOI: 10.1364/Isa.2013.Ith1D.4  0.849
2013 Lew MD, Backlund MP, Moerner WE. Rotational mobility of single molecules affects localization accuracy in super-resolution fluorescence microscopy. Nano Letters. 13: 3967-72. PMID 23360306 DOI: 10.1021/Nl304359P  0.84
2013 Backlund MP, Lew MD, Backer AS, Sahl SJ, Grover G, Agrawal A, Piestun R, Moerner WE. The Double-Helix Microscope Enables Precise and Accurate Measurement of 3D Single-Molecule Orientation and Localization Beyond the Diffraction Limit Ntm. DOI: 10.1364/Ntm.2013.Nm2B.2  0.851
2013 Lew MD, Backlund MP, Backer AS, Moerner WE. Optical methods for measuring single-molecule orientation and position: Implications for super-resolution microscopy Optics Infobase Conference Papers. DOI: 10.1364/Fio.2013.Fw6A.6  0.847
2013 Lew MD, Backlund MP, Backer AS, Sahl SJ, Grover G, Agrawal A, Piestun R, Moerner WE. Measuring the 3D position and orientation of single molecules simultaneously and accurately with the double helix microscope Cleo: Science and Innovations, Cleo_si 2013. CTu3N.3.  0.834
2012 Backlund MP, Lew MD, Backer AS, Sahl SJ, Grover G, Agrawal A, Piestun R, Moerner WE. Simultaneous, accurate measurement of the 3D position and orientation of single molecules. Proceedings of the National Academy of Sciences of the United States of America. 109: 19087-92. PMID 23129640 DOI: 10.1073/Pnas.1216687109  0.852
2012 Thompson MA, Lew MD, Moerner WE. Extending microscopic resolution with single-molecule imaging and active control. Annual Review of Biophysics. 41: 321-42. PMID 22577822 DOI: 10.1146/Annurev-Biophys-050511-102250  0.694
2012 Lee HL, Sahl SJ, Lew MD, Moerner WE. The double-helix microscope super-resolves extended biological structures by localizing single blinking molecules in three dimensions with nanoscale precision. Applied Physics Letters. 100: 153701-1537013. PMID 22550359 DOI: 10.1063/1.3700446  0.705
2011 Lew MD, Lee SF, Ptacin JL, Lee MK, Twieg RJ, Shapiro L, Moerner WE. Three-dimensional superresolution colocalization of intracellular protein superstructures and the cell surface in live Caulobacter crescentus. Proceedings of the National Academy of Sciences of the United States of America. 108: E1102-10. PMID 22031697 DOI: 10.1073/Pnas.1114444108  0.739
2011 Lew MD, Lee SF, Badieirostami M, Moerner WE. Corkscrew point spread function for far-field three-dimensional nanoscale localization of pointlike objects. Optics Letters. 36: 202-4. PMID 21263500 DOI: 10.1364/Ol.36.000202  0.709
2011 Lew MD, Lee SF, Moerner WE. Three-dimensional super-resolution imaging with a corkscrew point spread function Optics Infobase Conference Papers. DOI: 10.1364/Ntm.2011.Nmb2  0.72
2011 Lew MD, Lee SF, Ptacin JL, Lee MK, Shapiro L, Moerner WE. Super-resolution 3D co-localization of protein superstructures and the cellular surface in live caulobacter crescentus Optics Infobase Conference Papers. DOI: 10.1364/Fio.2011.Ftuh2  0.716
2010 Badieirostami M, Lew MD, Thompson MA, Moerner WE. Three-dimensional localization precision of the double-helix point spread function versus astigmatism and biplane. Applied Physics Letters. 97: 161103. PMID 21079725 DOI: 10.1063/1.3499652  0.626
2010 Lew MD, Thompson MA, Badieirostami M, Moerner WE. In vivo Three-Dimensional Superresolution Fluorescence Tracking using a Double-Helix Point Spread Function. Proceedings of Spie--the International Society For Optical Engineering. 7571: 75710Z. PMID 20563317 DOI: 10.1117/12.842608  0.665
2010 Thompson MA, Lew MD, Badieirostami M, Moerner WE. Localizing and tracking single nanoscale emitters in three dimensions with high spatiotemporal resolution using a double-helix point spread function. Nano Letters. 10: 211-8. PMID 20000821 DOI: 10.1021/Nl903295P  0.623
2010 Thompson MA, Lew MD, Badieirostami M, Moerner WE. Localizing and tracking single emitters in three dimensions using a double-helix point spread function Optics Infobase Conference Papers.  0.536
2009 Moerner WE, Thompson M, Lew M, Badieirostami M, Lord SJ, Conley NR, Lee HlD, Pavani SRP, Piestun R. Three-dimensional superresolution using single-molecule photoswitches and a double-helix PSF Optics Infobase Conference Papers.  0.738
2009 Lew M, Thompson MA, Badieirostami M, Moerner WE. Localization precision of three-dimensional superresolution fluorescence imaging using a double-helix point spread function Optics Infobase Conference Papers.  0.598
2008 Lew M, Cui X, Heng X, Yang C. Two-dimensional differential interference contrast microscopy based on four-hole variation of Young's interference Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6859. DOI: 10.1117/12.760118  0.634
2008 Cui X, Lew M, Yang C. Quantitative differential interference contrast microscopy based on structured-aperture interference Applied Physics Letters. 93: 091113. DOI: 10.1063/1.2977870  0.681
2007 Lew M, Cui X, Heng X, Yang C. Interference of a four-hole aperture for on-chip quantitative two-dimensional differential phase imaging. Optics Letters. 32: 2963-5. PMID 17938667 DOI: 10.1364/Ol.32.002963  0.633
2007 Cui X, Lew M, Heng X, Yang C. Oil-chip differential interference contrast (DIC) phase imager and beam profiler based on Young's interference Progress in Biomedical Optics and Imaging - Proceedings of Spie. 6441. DOI: 10.1117/12.699920  0.637
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