Year |
Citation |
Score |
2022 |
Kauppinen RA, Thotland J, Pisharady P, Lenglet C, Garwood M. WHITE MATTER MICROSTRUCTURE AND LONGITUDINAL RELAXATION TIME ANISOTORPY IN HUMAN BRAIN AT 3T AND 7T. Nmr in Biomedicine. e4815. PMID 35994269 DOI: 10.1002/nbm.4815 |
0.355 |
|
2021 |
Wearn AR, Nurdal V, Saunders-Jennings E, Knight MJ, Madan CR, Fallon SJ, Isotalus HK, Kauppinen RA, Coulthard EJ. T2 heterogeneity as an in vivo marker of microstructural integrity in medial temporal lobe subfields in ageing and mild cognitive impairment. Neuroimage. 238: 118214. PMID 34116150 DOI: 10.1016/j.neuroimage.2021.118214 |
0.304 |
|
2021 |
Wearn AR, Nurdal V, Saunders-Jennings E, Knight MJ, Madan CR, Fallon SJ, Isotalus HK, Kauppinen RA, Coulthard EJ. T2 heterogeneity as an in vivo marker of microstructural integrity in medial temporal lobe subfields in ageing and mild cognitive impairment. Neuroimage. 238: 118214. PMID 34116150 DOI: 10.1016/j.neuroimage.2021.118214 |
0.304 |
|
2020 |
McGarry BL, Damion RA, Chew I, Knight MJ, Harston GW, Carone D, Jezzard P, Sitaram A, Muir KW, Clatworthy P, Kauppinen RA. A Comparison of T Relaxation-Based MRI Stroke Timing Methods in Hyperacute Ischemic Stroke Patients: A Pilot Study. Journal of Central Nervous System Disease. 12: 1179573520943314. PMID 32963473 DOI: 10.1177/1179573520943314 |
0.794 |
|
2019 |
Knight MJ, Damion RA, McGarry BL, Bosnell R, Jokivarsi KT, Gröhn OHJ, Jezzard P, Harston GWJ, Carone D, Kennedy J, El-Tawil S, Elliot J, Muir KW, Clatworthy P, Kauppinen RA. Determining T2 relaxation time and stroke onset relationship in ischaemic stroke within apparent diffusion coefficient-defined lesions. A user-independent method for quantifying the impact of stroke in the human brain. Biomedical Spectroscopy and Imaging. 8: 11-28. PMID 31328097 DOI: 10.3233/Bsi-190185 |
0.794 |
|
2019 |
Damion R, Knight MJ, McGarry BL, Bosnell R, Jezzard P, Harston GWJ, Carone D, Kennedy J, El-Tawil S, Elliot J, Muir KW, Clatworthy P, Kauppinen RA. Quantifying T2 relaxation time changes within lesions defined by apparent diffusion coefficient in grey and white matter in acute stroke patients. Physics in Medicine and Biology. PMID 30921782 DOI: 10.1088/1361-6560/Ab1442 |
0.774 |
|
2018 |
Knight MJ, Damion RA, Kauppinen RA. Observation of Angular Dependence of T1 in the Human White Matter at 3T. Biomedical Spectroscopy and Imaging. 7: 125-133. PMID 30931248 DOI: 10.3233/Bsi-180183 |
0.736 |
|
2018 |
Knight MJ, Wearn A, Coulthard E, Kauppinen RA. T2 Relaxometry and Diffusion Tensor Indices of the Hippocampus and Entorhinal Cortex Improve Sensitivity and Specificity of MRI to Detect Amnestic Mild Cognitive Impairment and Alzheimer's Disease Dementia. Journal of Magnetic Resonance Imaging : Jmri. PMID 30209854 DOI: 10.1002/jmri.26195 |
0.315 |
|
2017 |
McGarry BL, Jokivarsi KT, Knight MJ, Grohn OHJ, Kauppinen RA. A Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia. Journal of Visualized Experiments : Jove. PMID 28994754 DOI: 10.3791/55277 |
0.846 |
|
2017 |
McGarry BL, Jokivarsi KT, Knight MJ, Grohn OHJ, Kauppinen RA. Magnetic Resonance Imaging Protocol for Stroke Onset Time Estimation in Permanent Cerebral Ischemia. Journal of Visualized Experiments : Jove. 2017. PMID 28979652 DOI: 10.3791/55277 |
0.846 |
|
2017 |
Norton TJT, Pereyra M, Knight MJ, McGarry BM, Jokivarsi KT, Gröhn OHJ, Kauppinen RA. Stroke Onset Time Determination Using MRI Relaxation Times without Non-Ischaemic Reference in A Rat Stroke Model. Biomedical Spectroscopy and Imaging. 6: 25-35. PMID 28685128 DOI: 10.3233/BSI-160155 |
0.667 |
|
2017 |
Knight MJ, Dillon S, Jarutyte L, Kauppinen RA. Magnetic Resonance Relaxation Anisotropy: Physical Principles and Uses in Microstructure Imaging. Biophysical Journal. 112: 1517-1528. PMID 28402893 DOI: 10.1016/j.bpj.2017.02.026 |
0.386 |
|
2017 |
Kauppinen RA, Knight MJ. Computed tomography-based acute stroke lesion timing and patient stratification. Annals of Neurology. PMID 28253543 DOI: 10.1002/ana.24913 |
0.465 |
|
2016 |
Knight MJ, McCann B, Tsivos D, Couthard E, Kauppinen RA. Quantitative T1 and T2 MRI signal characteristics in the human brain: different patterns of MR contrasts in normal ageing. Magma (New York, N.Y.). PMID 27333937 DOI: 10.1007/s10334-016-0573-0 |
0.344 |
|
2016 |
McGarry BL, Rogers HJ, Knight MJ, Jokivarsi KT, Sierra A, Gröhn OH, Kauppinen RA. Stroke onset time estimation from multispectral quantitative magnetic resonance imaging in a rat model of focal permanent cerebral ischemia. International Journal of Stroke : Official Journal of the International Stroke Society. PMID 27006425 DOI: 10.1177/1747493016641124 |
0.82 |
|
2016 |
McGarry BL, Rogers HJ, Knight MJ, Jokivarsi KT, Gröhn OH, Kauppinen RA. Determining Stroke Onset Time Using Quantitative MRI: High Accuracy, Sensitivity and Specificity Obtained from Magnetic Resonance Relaxation Times Cerebrovascular Diseases Extra. 6: 60-65. DOI: 10.1159/000448814 |
0.833 |
|
2015 |
Knight MJ, McGarry BL, Rogers HJ, Jokivarsi KT, Gröhn OH, Kauppinen RA. A spatiotemporal theory for MRI T2 relaxation time and apparent diffusion coefficient in the brain during acute ischaemia: Application and validation in a rat acute stroke model. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661188 DOI: 10.1177/0271678X15608394 |
0.835 |
|
2014 |
Rogers HJ, McGarry BL, Knight MJ, Jokivarsi KT, Gröhn OH, Kauppinen RA. Timing the ischaemic stroke by 1H-MRI: improved accuracy using absolute relaxation times over signal intensities. Neuroreport. 25: 1180-5. PMID 25116145 DOI: 10.1097/WNR.0000000000000238 |
0.827 |
|
2013 |
Jokivarsi KT, Liimatainen T, Kauppinen RA, Gröhn OH, Närväinen J. Relaxation along a fictitious field (RAFF) and Z-spectroscopy using alternating-phase irradiation (ZAPI) in permanent focal cerebral ischemia in rat. Plos One. 8: e69157. PMID 23874898 DOI: 10.1371/journal.pone.0069157 |
0.547 |
|
2010 |
Jokivarsi KT, Hiltunen Y, Gröhn H, Tuunanen P, Gröhn OH, Kauppinen RA. Estimation of the onset time of cerebral ischemia using T1rho and T2 MRI in rats. Stroke. 41: 2335-40. PMID 20814006 DOI: 10.1161/STROKEAHA.110.587394 |
0.439 |
|
2010 |
Jokivarsi KT, Hiltunen Y, Tuunanen PI, Kauppinen RA, Gröhn OH. Correlating tissue outcome with quantitative multiparametric MRI of acute cerebral ischemia in rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 30: 415-27. PMID 19904287 DOI: 10.1038/jcbfm.2009.236 |
0.538 |
|
2009 |
Jokivarsi KT, Niskanen JP, Michaeli S, Gröhn HI, Garwood M, Kauppinen RA, Gröhn OH. Quantitative assessment of water pools by T 1 rho and T 2 rho MRI in acute cerebral ischemia of the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 206-16. PMID 18827834 DOI: 10.1038/Jcbfm.2008.113 |
0.556 |
|
2007 |
Kettunen MI, Sierra A, Närväinen MJ, Valonen PK, Ylä-Herttuala S, Kauppinen RA, Gröhn OH. Low spin-lock field T1 relaxation in the rotating frame as a sensitive MR imaging marker for gene therapy treatment response in rat glioma. Radiology. 243: 796-803. PMID 17517934 DOI: 10.1148/radiol.2433052077 |
0.303 |
|
2005 |
Yrjänheikki J, Koistinaho J, Kettunen M, Kauppinen RA, Appel K, Hüll M, Fiebich BL. Long-term protective effect of atorvastatin in permanent focal cerebral ischemia. Brain Research. 1052: 174-9. PMID 16023089 DOI: 10.1016/J.Brainres.2005.06.004 |
0.37 |
|
2005 |
Gröhn HI, Michaeli S, Garwood M, Kauppinen RA, Gröhn OH. Quantitative T(1rho) and adiabatic Carr-Purcell T2 magnetic resonance imaging of human occipital lobe at 4 T. Magnetic Resonance in Medicine. 54: 14-9. PMID 15968651 DOI: 10.1002/mrm.20536 |
0.405 |
|
2005 |
Michaeli S, Gröhn H, Gröhn O, Sorce DJ, Kauppinen R, Springer CS, Uğurbil K, Garwood M. Exchange-influenced T2rho contrast in human brain images measured with adiabatic radio frequency pulses. Magnetic Resonance in Medicine. 53: 823-9. PMID 15799068 DOI: 10.1002/Mrm.20428 |
0.351 |
|
2005 |
Kavec M, Gröhn OH, Gröhn HI, Garwood M, Kauppinen RA. Dynamic dephasing changes in developing ischemic cerebral infarction in rats studied by Carr-Purcell T2 magnetic resonance imaging. Magnetic Resonance in Medicine. 53: 960-4. PMID 15799047 DOI: 10.1002/Mrm.20409 |
0.442 |
|
2005 |
Kettunen MI, Kauppinen RA, Gröhn OHJ. Dispersion of cerebral on-resonanceT 1 in the rotating frame (T 1ρ) in global ischaemia Applied Magnetic Resonance. 29: 89-106. DOI: 10.1007/BF03166957 |
0.31 |
|
2004 |
Kavec M, Gröhn OH, Kettunen MI, Silvennoinen MJ, Garwood M, Kauppinen RA. Acute cerebral ischemia in rats studied by Carr-Purcell spin-echo magnetic resonance imaging: assessment of blood oxygenation level-dependent and tissue effects on the transverse relaxation. Magnetic Resonance in Medicine. 51: 1138-46. PMID 15170833 DOI: 10.1002/Mrm.20089 |
0.314 |
|
2004 |
Kettunen MI, Gröhn OH, Kauppinen RA. Quantitative T1rho NMR spectroscopy of rat cerebral metabolites in vivo: effects of global ischemia. Magnetic Resonance in Medicine. 51: 875-80. PMID 15122667 DOI: 10.1002/mrm.20099 |
0.405 |
|
2004 |
Kavec M, Usenius JP, Tuunanen PI, Rissanen A, Kauppinen RA. Assessment of cerebral hemodynamics and oxygen extraction using dynamic susceptibility contrast and spin echo blood oxygenation level-dependent magnetic resonance imaging: applications to carotid stenosis patients. Neuroimage. 22: 258-67. PMID 15110016 DOI: 10.1016/j.neuroimage.2004.01.009 |
0.312 |
|
2004 |
Mäkelä HI, De Vita E, Gröhn OH, Kettunen MI, Kavec M, Lythgoe M, Garwood M, Ordidge R, Kauppinen RA. B0 dependence of the on-resonance longitudinal relaxation time in the rotating frame (T1rho) in protein phantoms and rat brain in vivo. Magnetic Resonance in Medicine. 51: 4-8. PMID 14705038 DOI: 10.1002/Mrm.10669 |
0.337 |
|
2003 |
Gröhn OH, Valonen PK, Lehtimäki KK, Väisänen TH, Kettunen MI, Ylä-Herttuala S, Kauppinen RA, Garwood M. Novel magnetic resonance imaging contrasts for monitoring response to gene therapy in rat glioma. Cancer Research. 63: 7571-4. PMID 14633668 |
0.351 |
|
2003 |
Gröhn OH, Mäkelä HI, Lukkarinen JA, DelaBarre L, Lin J, Garwood M, Kauppinen RA. On- and off-resonance T(1rho) MRI in acute cerebral ischemia of the rat. Magnetic Resonance in Medicine. 49: 172-6. PMID 12509834 DOI: 10.1002/Mrm.10356 |
0.412 |
|
2002 |
Kettunen MI, Gröhn OH, Silvennoinen MJ, Penttonen M, Kauppinen RA. Effects of intracellular pH, blood, and tissue oxygen tension on T1rho relaxation in rat brain. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 48: 470-7. PMID 12210911 DOI: 10.1002/Mrm.10233 |
0.342 |
|
2002 |
Mäkelä HI, Kettunen MI, Gröhn OH, Kauppinen RA. Quantitative T(1rho) and magnetization transfer magnetic resonance imaging of acute cerebral ischemia in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 547-58. PMID 11973427 DOI: 10.1097/00004647-200205000-00006 |
0.458 |
|
2002 |
Hakumäki JM, Gröhn OH, Tyynelä K, Valonen P, Ylä-Herttuala S, Kauppinen RA. Early gene therapy-induced apoptotic response in BT4C gliomas by magnetic resonance relaxation contrast T1 in the rotating frame. Cancer Gene Therapy. 9: 338-45. PMID 11960284 DOI: 10.1038/sj.cgt.7700450 |
0.349 |
|
2002 |
Kettunen MI, Gröhn OH, Silvennoinen MJ, Penttonen M, Kauppinen RA. Quantitative assessment of the balance between oxygen delivery and consumption in the rat brain after transient ischemia with T2 -BOLD magnetic resonance imaging. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 22: 262-70. PMID 11891431 DOI: 10.1097/00004647-200203000-00003 |
0.397 |
|
2002 |
Gröhn OH, Kauppinen RA. Assessment of brain tissue viability in acute ischemic stroke by BOLD MRI. Nmr in Biomedicine. 14: 432-40. PMID 11746935 DOI: 10.1002/NBM.739 |
0.575 |
|
2001 |
Kettunen MI, Gröhn OH, Penttonen M, Kauppinen RA. Cerebral T1rho relaxation time increases immediately upon global ischemia in the rat independently of blood glucose and anoxic depolarization. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 46: 565-72. PMID 11550250 DOI: 10.1002/Mrm.1228 |
0.373 |
|
2001 |
Zhou J, Golay X, van Zijl PC, Silvennoinen MJ, Kauppinen R, Pekar J, Kraut M. Inverse T(2) contrast at 1.5 Tesla between gray matter and white matter in the occipital lobe of normal adult human brain. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 46: 401-6. PMID 11477646 DOI: 10.1002/mrm.1204 |
0.331 |
|
2001 |
Kavec M, Gröhn OH, Kettunen MI, Silvennoinen MJ, Penttonen M, Kauppinen RA. Use of spin echo T(2) BOLD in assessment of cerebral misery perfusion at 1.5 T. Magma (New York, N.Y.). 12: 32-9. PMID 11255090 DOI: 10.1007/BF02678271 |
0.48 |
|
2001 |
Kettunen MI, Gröhn OH, Lukkarinen JA, Vainio P, Silvennoinen MJ, Kauppinen RA. Interrelations of T(1) and diffusion of water in acute cerebral ischemia of the rat. Magnetic Resonance in Medicine. 44: 833-9. PMID 11108619 DOI: 10.1002/1522-2594(200012)44:6<833::AID-MRM3>3.0.CO;2-F |
0.446 |
|
2000 |
Gröhn OHJ, Kettunen MI, Mäkelä HI, Penttonen M, Pitkänen A, Lukkarinen JA, Kauppinen RA. Early detection of irreversible cerebral ischemia in the rat using dispersion of the magnetic resonance imaging relaxation time, T1rho. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 1457-66. PMID 11043908 DOI: 10.1097/00004647-200010000-00007 |
0.553 |
|
2000 |
Gröhn OH, Kettunen MI, Penttonen M, Oja JM, van Zijl PC, Kauppinen RA. Graded reduction of cerebral blood flow in rat as detected by the nuclear magnetic resonance relaxation time T2: a theoretical and experimental approach. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 316-26. PMID 10698069 DOI: 10.1097/00004647-200002000-00013 |
0.42 |
|
1999 |
Gröhn OH, Lukkarinen JA, Silvennoinen MJ, Pitkänen A, van Zijl PC, Kauppinen RA. Quantitative magnetic resonance imaging assessment of cerebral ischemia in rat using on-resonance T(1) in the rotating frame. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 42: 268-76. PMID 10440951 DOI: 10.1002/(SICI)1522-2594(199908)42:2<268::AID-MRM8>3.0.CO;2-A |
0.415 |
|
1998 |
Lukkarinen JA, Kauppinen RA, Gröhn OH, Oja JM, Sinervirta R, Järvinen A, Alhonen LI, Jänne J. Neuroprotective role of ornithine decarboxylase activation in transient focal cerebral ischaemia: a study using ornithine decarboxylase-overexpressing transgenic rats. The European Journal of Neuroscience. 10: 2046-55. PMID 9753092 DOI: 10.1046/j.1460-9568.1998.00216.x |
0.441 |
|
1998 |
Gröhn OH, Lukkarinen JA, Oja JM, van Zijl PC, Ulatowski JA, Traystman RJ, Kauppinen RA. Noninvasive detection of cerebral hypoperfusion and reversible ischemia from reductions in the magnetic resonance imaging relaxation time, T2. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 911-20. PMID 9701353 DOI: 10.1097/00004647-199808000-00012 |
0.45 |
|
1997 |
Hakumäki JM, Gröhn OH, Pirttilä TR, Kauppinen RA. Increased macromolecular resonances in the rat cerebral cortex during severe energy failure as detected by 1H nuclear magnetic resonance spectroscopy. Neuroscience Letters. 212: 151-4. PMID 8843095 DOI: 10.1016/0304-3940(96)12797-X |
0.315 |
|
1993 |
Gadian DG, Williams SR, Bates TE, Kauppinen RA. NMR spectroscopy: current status and future possibilities. Acta Neurochirurgica. Supplementum. 57: 1-8. PMID 8421944 DOI: 10.1007/978-3-7091-9266-5_1 |
0.45 |
|
1989 |
Brooks KJ, Kauppinen RA, Williams SR, Bachelard HS, Bates TE, Gadian DG. Ammonia causes a drop in intracellular pH in metabolizing cortical brain slices. A [31P]- and [1H]nuclear magnetic resonance study. Neuroscience. 33: 185-92. PMID 2574835 DOI: 10.1016/0306-4522(89)90320-5 |
0.453 |
|
1989 |
Bates TE, Williams SR, Kauppinen RA, Gadian DG. Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study. Journal of Neurochemistry. 53: 102-10. PMID 2566653 DOI: 10.1111/J.1471-4159.1989.Tb07300.X |
0.474 |
|
1989 |
Gill SS, Small RK, Thomas DG, Patel P, Porteous R, Van Bruggen N, Gadian DG, Kauppinen RA, Williams SR. Brain metabolites as 1H NMR markers of neuronal and glial disorders. Nmr in Biomedicine. 2: 196-200. PMID 2561957 DOI: 10.1002/Nbm.1940020505 |
0.436 |
|
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