| Year |
Citation |
Score |
| 2024 |
Abdel-Moneim AS, Murovska M, Söderlund-Venermo M, Vakharia VN, Wilson WC, Gladue DP, Moore MD, Alonso C, Abdelwahab SF, Venter M, Malik YS, Zhengli S, Saxena SK, Varma A, Kuhn RJ. WSV2023 - The second meeting of the world society for virology: One health - One world - One virology. Virology. 594: 110049. PMID 38527382 DOI: 10.1016/j.virol.2024.110049 |
0.302 |
|
| 2023 |
Rabelo VW, da Silva VD, Sanchez Nuñez ML, Dos Santos Corrêa Amorim L, Buarque CD, Kuhn RJ, Abreu PA, Nunes de Palmer Paixão IC. Antiviral evaluation of 1,4-disubstituted-1,2,3-triazole derivatives against Chikungunya virus. Future Virology. 18: 865-880. PMID 37974899 DOI: 10.2217/fvl-2023-0142 |
0.425 |
|
| 2023 |
Kuhn RJ, Barrett ADT, Desilva AM, Harris E, Kramer LD, Montgomery RR, Pierson TC, Sette A, Diamond MS. A Prototype-Pathogen Approach for the Development of Flavivirus Countermeasures. The Journal of Infectious Diseases. 228: S398-S413. PMID 37849402 DOI: 10.1093/infdis/jiad193 |
0.317 |
|
| 2023 |
Wang Z, Fokine A, Guo X, Jiang W, Rossmann MG, Kuhn RJ, Luo ZH, Klose T. Structure of Phage XM1, a Simple Contractile DNA Injection Machine. Viruses. 15. PMID 37632015 DOI: 10.3390/v15081673 |
0.319 |
|
| 2023 |
Williamson LE, Bandyopadhyay A, Bailey K, Sirohi D, Klose T, Julander JG, Kuhn RJ, Crowe JE. Structural constraints link differences in neutralization potency of human anti-Eastern equine encephalitis virus monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 120: e2213690120. PMID 36961925 DOI: 10.1073/pnas.2213690120 |
0.323 |
|
| 2023 |
A Dowd K, Sirohi D, D Speer S, VanBlargan LA, Chen RE, Mukherjee S, Whitener BM, Govero J, Aleshnick M, Larman B, Sukupolvi-Petty S, Sevvana M, Miller AS, Klose T, Zheng A, ... ... Kuhn RJ, et al. prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis. Proceedings of the National Academy of Sciences of the United States of America. 120: e2218899120. PMID 36638211 DOI: 10.1073/pnas.2218899120 |
0.341 |
|
| 2022 |
Singh VA, Kumar CS, Khare B, Kuhn RJ, Banerjee M, Tomar S. Surface decorated reporter-tagged chikungunya virus-like particles for clinical diagnostics and identification of virus entry inhibitors. Virology. 578: 92-102. PMID 36473281 DOI: 10.1016/j.virol.2022.11.012 |
0.704 |
|
| 2022 |
Khare B, Kuhn RJ. The Japanese Encephalitis Antigenic Complex Viruses: From Structure to Immunity. Viruses. 14. PMID 36298768 DOI: 10.3390/v14102213 |
0.314 |
|
| 2022 |
Sengupta R, Mihelc EM, Angel S, Lanman JK, Kuhn RJ, Stahelin RV. Contribution of the Golgi apparatus in morphogenesis of a virus-induced cytopathic vacuolar system. Life Science Alliance. 5. PMID 36137747 DOI: 10.26508/lsa.202000887 |
0.707 |
|
| 2022 |
Chen CL, Klose T, Sun C, Kim AS, Buda G, Rossmann MG, Diamond MS, Klimstra WB, Kuhn RJ. Cryo-EM structures of alphavirus conformational intermediates in low pH-triggered prefusion states. Proceedings of the National Academy of Sciences of the United States of America. 119: e2114119119. PMID 35867819 DOI: 10.1073/pnas.2114119119 |
0.355 |
|
| 2022 |
Cao TM, Kuhn RJ. Construction of Genomic and Sub-Genomic Dengue Infectious Replicons. Methods in Molecular Biology (Clifton, N.J.). 2409: 77-96. PMID 34709637 DOI: 10.1007/978-1-0716-1879-0_7 |
0.343 |
|
| 2021 |
Khare B, Klose T, Fang Q, Rossmann MG, Kuhn RJ. Structure of Usutu virus SAAR-1776 displays fusion loop asymmetry. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34417300 DOI: 10.1073/pnas.2107408118 |
0.483 |
|
| 2021 |
Wessel AW, Dowd KA, Biering SB, Zhang P, Edeling MA, Nelson CA, Funk KE, DeMaso CR, Klein RS, Smith JL, Cao TM, Kuhn RJ, Fremont DH, Harris E, Pierson TC, et al. Levels of circulating NS1 impact West Nile virus spread to the brain. Journal of Virology. JVI0084421. PMID 34346770 DOI: 10.1128/JVI.00844-21 |
0.392 |
|
| 2021 |
Coelho DR, Carneiro PH, Mendes-Monteiro L, Conde JN, Andrade I, Cao T, Allonso D, White-Dibiasio M, Kuhn RJ, Mohana-Borges R. ApoA1 neutralizes pro-inflammatory effects of Dengue virus NS1 protein and modulates the viral immune evasion. Journal of Virology. PMID 33827950 DOI: 10.1128/JVI.01974-20 |
0.323 |
|
| 2020 |
Nicholls CMR, Sevvana M, Kuhn RJ. Structure-guided paradigm shifts in flavivirus assembly and maturation mechanisms. Advances in Virus Research. 108: 33-83. PMID 33837721 DOI: 10.1016/bs.aivir.2020.08.003 |
0.313 |
|
| 2020 |
Sevvana M, Rogers TF, Miller AS, Long F, Klose T, Beutler N, Lai YC, Parren M, Walker LM, Buda G, Burton DR, Rossmann MG, Kuhn RJ. Structural Basis of Zika Virus Specific Neutralization in Subsequent Flavivirus Infections. Viruses. 12. PMID 33255202 DOI: 10.3390/v12121346 |
0.443 |
|
| 2020 |
Sevvana M, Kuhn RJ. Mapping the diverse structural landscape of the flavivirus antibody repertoire. Current Opinion in Virology. 45: 51-64. PMID 32801077 DOI: 10.1016/j.coviro.2020.07.006 |
0.383 |
|
| 2020 |
Powell LA, Miller A, Fox JM, Kose N, Klose T, Kim AS, Bombardi R, Tennekoon RN, Dharshan de Silva A, Carnahan RH, Diamond MS, Rossmann MG, Kuhn RJ, Crowe JE. Human mAbs Broadly Protect against Arthritogenic Alphaviruses by Recognizing Conserved Elements of the Mxra8 Receptor-Binding Site. Cell Host & Microbe. PMID 32783883 DOI: 10.1016/J.Chom.2020.07.008 |
0.304 |
|
| 2020 |
Srivastava M, Zhang Y, Chen J, Sirohi D, Miller A, Zhang Y, Chen Z, Lu H, Xu J, Kuhn RJ, Andy Tao W. Chemical proteomics tracks virus entry and uncovers NCAM1 as Zika virus receptor. Nature Communications. 11: 3896. PMID 32753727 DOI: 10.1038/S41467-020-17638-Y |
0.441 |
|
| 2020 |
Fatma B, Kumar R, Singh VA, Nehul S, Sharma R, Kesari P, Kuhn RJ, Tomar S. Alphavirus capsid protease inhibitors as potential antiviral agents for Chikungunya infection. Antiviral Research. 104808. PMID 32380148 DOI: 10.1016/j.antiviral.2020.104808 |
0.703 |
|
| 2020 |
Kesari AS, Heintz VJ, Poudyal S, Miller AS, Kuhn RJ, LaCount DJ. Zika virus NS5 localizes at centrosomes during cell division. Virology. 541: 52-62. PMID 32056715 DOI: 10.1016/J.Virol.2019.11.018 |
0.433 |
|
| 2019 |
Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe JE, Rossmann MG. Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope. Proceedings of the National Academy of Sciences of the United States of America. PMID 30642974 DOI: 10.1073/pnas.1815432116 |
0.382 |
|
| 2018 |
Sevvana M, Long F, Miller AS, Klose T, Buda G, Sun L, Kuhn RJ, Rossmann MG. Refinement and Analysis of the Mature Zika Virus Cryo-EM Structure at 3.1 Å Resolution. Structure (London, England : 1993). PMID 29958768 DOI: 10.1016/J.Str.2018.05.006 |
0.417 |
|
| 2018 |
Narwal M, Singh H, Pratap S, Malik A, Kuhn RJ, Kumar P, Tomar S. Crystal structure of chikungunya virus nsP2 cysteine protease reveals a putative flexible loop blocking its active site. International Journal of Biological Macromolecules. PMID 29730006 DOI: 10.1016/j.ijbiomac.2018.05.007 |
0.691 |
|
| 2018 |
Chotiwan N, Andre BG, Sanchez-Vargas I, Islam MN, Grabowski JM, Hopf-Jannasch A, Gough E, Nakayasu E, Blair CD, Belisle JT, Hill CA, Kuhn RJ, Perera R. Dynamic remodeling of lipids coincides with dengue virus replication in the midgut of Aedes aegypti mosquitoes. Plos Pathogens. 14: e1006853. PMID 29447265 DOI: 10.1371/Journal.Ppat.1006853 |
0.674 |
|
| 2018 |
Hasan SS, Sevvana M, Kuhn RJ, Rossmann MG. Structural biology of Zika virus and other flaviviruses. Nature Structural & Molecular Biology. 25: 13-20. PMID 29323278 DOI: 10.1038/S41594-017-0010-8 |
0.427 |
|
| 2018 |
Goo L, DeMaso CR, Pelc RS, Ledgerwood JE, Graham BS, Kuhn RJ, Pierson TC. The Zika virus envelope protein glycan loop regulates virion antigenicity. Virology. 515: 191-202. PMID 29304471 DOI: 10.1016/J.Virol.2017.12.032 |
0.406 |
|
| 2017 |
Sirohi D, Kuhn RJ. Zika Virus Structure, Maturation, and Receptors. The Journal of Infectious Diseases. 216: S935-S944. PMID 29267925 DOI: 10.1093/infdis/jix515 |
0.347 |
|
| 2017 |
Jardetzky T, Kuhn R, Lamb R. Editorial overview: Virus structure and functions. Current Opinion in Virology. 24: ix. PMID 28743434 DOI: 10.1016/J.Coviro.2017.07.006 |
0.41 |
|
| 2017 |
Sirohi D, Kuhn RJ. Can an FDA-Approved Alzheimer's Drug Be Repurposed for Alleviating Neuronal Symptoms of Zika Virus? Mbio. 8. PMID 28655823 DOI: 10.1128/mBio.00916-17 |
0.323 |
|
| 2017 |
Hasan SS, Miller A, Sapparapu G, Fernandez E, Klose T, Long F, Fokine A, Porta JC, Jiang W, Diamond MS, Crowe JE, Kuhn RJ, Rossmann MG. A human antibody against Zika virus crosslinks the E protein to prevent infection. Nature Communications. 8: 14722. PMID 28300075 DOI: 10.1038/Ncomms14722 |
0.307 |
|
| 2017 |
Jose J, Taylor AB, Kuhn RJ. Spatial and Temporal Analysis of Alphavirus Replication and Assembly in Mammalian and Mosquito Cells. Mbio. 8. PMID 28196962 DOI: 10.1128/mBio.02294-16 |
0.415 |
|
| 2017 |
Grabowski JM, Gulia-Nuss M, Kuhn RJ, Hill CA. RNAi reveals proteins for metabolism and protein processing associated with Langat virus infection in Ixodes scapularis (black-legged tick) ISE6 cells. Parasites & Vectors. 10: 24. PMID 28086865 DOI: 10.1186/S13071-016-1944-0 |
0.323 |
|
| 2017 |
Prasad VM, Miller AS, Klose T, Sirohi D, Buda G, Jiang W, Kuhn RJ, Rossmann MG. Structure of the immature Zika virus at 9 Å resolution. Nature Structural & Molecular Biology. PMID 28067914 DOI: 10.1038/Nsmb.3352 |
0.385 |
|
| 2016 |
Brown WC, Akey DL, Konwerski JR, Tarrasch JT, Skiniotis G, Kuhn RJ, Smith JL. Extended surface for membrane association in Zika virus NS1 structure. Nature Structural & Molecular Biology. PMID 27455458 DOI: 10.1038/Nsmb.3268 |
0.405 |
|
| 2016 |
Mukherjee S, Sirohi D, Dowd KA, Chen Z, Diamond MS, Kuhn RJ, Pierson TC. Enhancing dengue virus maturation using a stable furin over-expressing cell line. Virology. 497: 33-40. PMID 27420797 DOI: 10.1016/J.Virol.2016.06.022 |
0.427 |
|
| 2016 |
Sirohi D, Chen Z, Sun L, Klose T, Pierson TC, Rossmann MG, Kuhn RJ. The 3.8 Å resolution cryo-EM structure of Zika virus. Science (New York, N.Y.). PMID 27033547 DOI: 10.1126/Science.Aaf5316 |
0.481 |
|
| 2016 |
Grabowski JM, Perera R, Roumani AM, Hedrick VE, Inerowicz HD, Hill CA, Kuhn RJ. Changes in the Proteome of Langat-Infected Ixodes scapularis ISE6 Cells: Metabolic Pathways Associated with Flavivirus Infection. Plos Neglected Tropical Diseases. 10: e0004180. PMID 26859745 DOI: 10.1371/Journal.Pntd.0004180 |
0.572 |
|
| 2016 |
Gulia-Nuss M, Nuss AB, Meyer JM, Sonenshine DE, Roe RM, Waterhouse RM, Sattelle DB, de la Fuente J, Ribeiro JM, Megy K, Thimmapuram J, Miller JR, Walenz BP, Koren S, Hostetler JB, ... ... Kuhn RJ, et al. Genomic insights into the Ixodes scapularis tick vector of Lyme disease. Nature Communications. 7: 10507. PMID 26856261 DOI: 10.1038/Ncomms10507 |
0.589 |
|
| 2015 |
Jose J, Tang J, Taylor AB, Baker TS, Kuhn RJ. Fluorescent Protein-Tagged Sindbis Virus E2 Glycoprotein Allows Single Particle Analysis of Virus Budding from Live Cells. Viruses. 7: 6182-6199. PMID 26633461 DOI: 10.3390/V7122926 |
0.455 |
|
| 2015 |
Kuhn RJ, Dowd KA, Beth Post C, Pierson TC. Shake, rattle, and roll: Impact of the dynamics of flavivirus particles on their interactions with the host. Virology. 479: 508-517. PMID 25835729 DOI: 10.1016/J.Virol.2015.03.025 |
0.402 |
|
| 2015 |
Akey DL, Brown WC, Jose J, Kuhn RJ, Smith JL. Structure-guided insights on the role of NS1 in flavivirus infection. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 37: 489-94. PMID 25761098 DOI: 10.1002/Bies.201400182 |
0.363 |
|
| 2015 |
Zhang X, Sheng J, Austin SK, Hoornweg TE, Smit JM, Kuhn RJ, Diamond MS, Rossmann MG. Structure of acidic pH dengue virus showing the fusogenic glycoprotein trimers. Journal of Virology. 89: 743-50. PMID 25355881 DOI: 10.1128/Jvi.02411-14 |
0.395 |
|
| 2014 |
Apte-Sengupta S, Sirohi D, Kuhn RJ. Coupling of replication and assembly in flaviviruses. Current Opinion in Virology. 9: 134-42. PMID 25462445 DOI: 10.1016/j.coviro.2014.09.020 |
0.408 |
|
| 2014 |
Aggarwal M, Dhindwal S, Kumar P, Kuhn RJ, Tomar S. trans-Protease activity and structural insights into the active form of the alphavirus capsid protease. Journal of Virology. 88: 12242-53. PMID 25100849 DOI: 10.1128/JVI.01692-14 |
0.663 |
|
| 2014 |
Dowd KA, Mukherjee S, Kuhn RJ, Pierson TC. Combined effects of the structural heterogeneity and dynamics of flaviviruses on antibody recognition. Journal of Virology. 88: 11726-37. PMID 25078693 DOI: 10.1128/Jvi.01140-14 |
0.324 |
|
| 2014 |
Yun SI, Song BH, Kim JK, Yun GN, Lee EY, Li L, Kuhn RJ, Rossmann MG, Morrey JD, Lee YM. A molecularly cloned, live-attenuated japanese encephalitis vaccine SA14-14-2 virus: a conserved single amino acid in the ij Hairpin of the Viral E glycoprotein determines neurovirulence in mice. Plos Pathogens. 10: e1004290. PMID 25077483 DOI: 10.1371/Journal.Ppat.1004290 |
0.404 |
|
| 2014 |
Schnettler E, Tykalová H, Watson M, Sharma M, Sterken MG, Obbard DJ, Lewis SH, McFarlane M, Bell-Sakyi L, Barry G, Weisheit S, Best SM, Kuhn RJ, Pijlman GP, Chase-Topping ME, et al. Induction and suppression of tick cell antiviral RNAi responses by tick-borne flaviviruses. Nucleic Acids Research. 42: 9436-46. PMID 25053841 DOI: 10.1093/Nar/Gku657 |
0.361 |
|
| 2014 |
Langevin SA, Bowen RA, Reisen WK, Andrade CC, Ramey WN, Maharaj PD, Anishchenko M, Kenney JL, Duggal NK, Romo H, Bera AK, Sanders TA, Bosco-Lauth A, Smith JL, Kuhn R, et al. Host competence and helicase activity differences exhibited by West Nile viral variants expressing NS3-249 amino acid polymorphisms. Plos One. 9: e100802. PMID 24971589 DOI: 10.1371/Journal.Pone.0100802 |
0.396 |
|
| 2014 |
Porta J, Jose J, Roehrig JT, Blair CD, Kuhn RJ, Rossmann MG. Locking and blocking the viral landscape of an alphavirus with neutralizing antibodies. Journal of Virology. 88: 9616-23. PMID 24920796 DOI: 10.1128/Jvi.01286-14 |
0.307 |
|
| 2014 |
Junjhon J, Pennington JG, Edwards TJ, Perera R, Lanman J, Kuhn RJ. Ultrastructural characterization and three-dimensional architecture of replication sites in dengue virus-infected mosquito cells. Journal of Virology. 88: 4687-97. PMID 24522909 DOI: 10.1128/JVI.00118-14 |
0.692 |
|
| 2014 |
Akey DL, Brown WC, Dutta S, Konwerski J, Jose J, Jurkiw TJ, DelProposto J, Ogata CM, Skiniotis G, Kuhn RJ, Smith JL. Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system. Science (New York, N.Y.). 343: 881-5. PMID 24505133 DOI: 10.1126/Science.1247749 |
0.309 |
|
| 2014 |
Plevka P, Lim PY, Perera R, Cardosa J, Suksatu A, Kuhn RJ, Rossmann MG. Neutralizing antibodies can initiate genome release from human enterovirus 71. Proceedings of the National Academy of Sciences of the United States of America. 111: 2134-9. PMID 24469789 DOI: 10.1073/Pnas.1320624111 |
0.647 |
|
| 2013 |
Dai HS, Liu Z, Jiang W, Kuhn RJ. Directed evolution of a virus exclusively utilizing human epidermal growth factor receptor as the entry receptor. Journal of Virology. 87: 11231-43. PMID 23926357 DOI: 10.1128/Jvi.01054-13 |
0.355 |
|
| 2013 |
Keating JA, Bhattacharya D, Lim PY, Falk S, Weisblum B, Bernard KA, Sharma M, Kuhn RJ, Striker R. West Nile virus methyltransferase domain interacts with protein kinase G. Virology Journal. 10: 242. PMID 23876037 DOI: 10.1186/1743-422X-10-242 |
0.403 |
|
| 2013 |
Snyder JE, Kulcsar KA, Schultz KL, Riley CP, Neary JT, Marr S, Jose J, Griffin DE, Kuhn RJ. Functional characterization of the alphavirus TF protein. Journal of Virology. 87: 8511-23. PMID 23720714 DOI: 10.1128/Jvi.00449-13 |
0.396 |
|
| 2013 |
Catanese MT, Uryu K, Kopp M, Edwards TJ, Andrus L, Rice WJ, Silvestry M, Kuhn RJ, Rice CM. Ultrastructural analysis of hepatitis C virus particles. Proceedings of the National Academy of Sciences of the United States of America. 110: 9505-10. PMID 23690609 DOI: 10.1073/Pnas.1307527110 |
0.506 |
|
| 2013 |
Zhang X, Sheng J, Plevka P, Kuhn RJ, Diamond MS, Rossmann MG. Dengue structure differs at the temperatures of its human and mosquito hosts. Proceedings of the National Academy of Sciences of the United States of America. 110: 6795-9. PMID 23569243 DOI: 10.1073/Pnas.1304300110 |
0.384 |
|
| 2013 |
Plevka P, Perera R, Yap ML, Cardosa J, Kuhn RJ, Rossmann MG. Structure of human enterovirus 71 in complex with a capsid-binding inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 110: 5463-7. PMID 23509286 DOI: 10.1073/Pnas.1222379110 |
0.648 |
|
| 2012 |
Aggarwal M, Tapas S, Preeti, Siwach A, Kumar P, Kuhn RJ, Tomar S. Crystal structure of aura virus capsid protease and its complex with dioxane: new insights into capsid-glycoprotein molecular contacts. Plos One. 7: e51288. PMID 23251484 DOI: 10.1371/journal.pone.0051288 |
0.702 |
|
| 2012 |
Snyder JE, Berrios CJ, Edwards TJ, Jose J, Perera R, Kuhn RJ. Probing the early temporal and spatial interaction of the Sindbis virus capsid and E2 proteins with reverse genetics. Journal of Virology. 86: 12372-83. PMID 22951842 DOI: 10.1128/JVI.01220-12 |
0.702 |
|
| 2012 |
Plevka P, Perera R, Cardosa J, Kuhn RJ, Rossmann MG. Structure determination of enterovirus 71. Acta Crystallographica. Section D, Biological Crystallography. 68: 1217-22. PMID 22948923 DOI: 10.1107/S0907444912025772 |
0.561 |
|
| 2012 |
Battisti AJ, Yoder JD, Plevka P, Winkler DC, Prasad VM, Kuhn RJ, Frey TK, Steven AC, Rossmann MG. Cryo-electron tomography of rubella virus. Journal of Virology. 86: 11078-85. PMID 22855483 DOI: 10.1128/Jvi.01390-12 |
0.74 |
|
| 2012 |
Perera R, Riley C, Isaac G, Hopf-Jannasch AS, Moore RJ, Weitz KW, Pasa-Tolic L, Metz TO, Adamec J, Kuhn RJ. Dengue virus infection perturbs lipid homeostasis in infected mosquito cells. Plos Pathogens. 8: e1002584. PMID 22457619 DOI: 10.1371/Journal.Ppat.1002584 |
0.65 |
|
| 2012 |
Botting C, Kuhn RJ. Novel approaches to flavivirus drug discovery. Expert Opinion On Drug Discovery. 7: 417-28. PMID 22439769 DOI: 10.1517/17460441.2012.673579 |
0.35 |
|
| 2012 |
Plevka P, Perera R, Cardosa J, Kuhn RJ, Rossmann MG. Crystal structure of human enterovirus 71. Science (New York, N.Y.). 336: 1274. PMID 22383808 DOI: 10.1126/Science.1218713 |
0.618 |
|
| 2012 |
Pierson TC, Kuhn RJ. Capturing a virus while it catches its breath. Structure (London, England : 1993). 20: 200-2. PMID 22325768 DOI: 10.1016/j.str.2012.01.014 |
0.32 |
|
| 2012 |
Jose J, Przybyla L, Edwards TJ, Perera R, Burgner JW, Kuhn RJ. Interactions of the cytoplasmic domain of Sindbis virus E2 with nucleocapsid cores promote alphavirus budding. Journal of Virology. 86: 2585-99. PMID 22190727 DOI: 10.1128/JVI.05860-11 |
0.689 |
|
| 2011 |
Aggarwal M, Dhindwal S, Pratap S, Kuhn RJ, Kumar P, Tomar S. Crystallization, high-resolution data collection and preliminary crystallographic analysis of Aura virus capsid protease and its complex with dioxane. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1394-8. PMID 22102240 DOI: 10.1107/S174430911103404X |
0.628 |
|
| 2011 |
Tang J, Jose J, Chipman P, Zhang W, Kuhn RJ, Baker TS. Molecular links between the E2 envelope glycoprotein and nucleocapsid core in Sindbis virus. Journal of Molecular Biology. 414: 442-59. PMID 22001018 DOI: 10.1016/J.Jmb.2011.09.045 |
0.464 |
|
| 2011 |
Khadka S, Vangeloff AD, Zhang C, Siddavatam P, Heaton NS, Wang L, Sengupta R, Sahasrabudhe S, Randall G, Gribskov M, Kuhn RJ, Perera R, LaCount DJ. A physical interaction network of dengue virus and human proteins. Molecular & Cellular Proteomics : McP. 10: M111.012187. PMID 21911577 DOI: 10.1074/Mcp.M111.012187 |
0.743 |
|
| 2011 |
Tomar S, Narwal M, Harms E, Smith JL, Kuhn RJ. Heterologous production, purification and characterization of enzymatically active Sindbis virus nonstructural protein nsP1. Protein Expression and Purification. 79: 277-84. PMID 21693190 DOI: 10.1016/J.Pep.2011.05.022 |
0.664 |
|
| 2011 |
Plevka P, Battisti AJ, Junjhon J, Winkler DC, Holdaway HA, Keelapang P, Sittisombut N, Kuhn RJ, Steven AC, Rossmann MG. Maturation of flaviviruses starts from one or more icosahedrally independent nucleation centres. Embo Reports. 12: 602-6. PMID 21566648 DOI: 10.1038/Embor.2011.75 |
0.36 |
|
| 2011 |
Snyder JE, Azizgolshani O, Wu B, He Y, Lee AC, Jose J, Suter DM, Knobler CM, Gelbart WM, Kuhn RJ. Rescue of infectious particles from preassembled alphavirus nucleocapsid cores. Journal of Virology. 85: 5773-81. PMID 21471237 DOI: 10.1128/Jvi.00039-11 |
0.482 |
|
| 2010 |
Li L, Jose J, Xiang Y, Kuhn RJ, Rossmann MG. Structural changes of envelope proteins during alphavirus fusion. Nature. 468: 705-8. PMID 21124457 DOI: 10.1038/Nature09546 |
0.354 |
|
| 2010 |
Kaufmann B, Vogt MR, Goudsmit J, Holdaway HA, Aksyuk AA, Chipman PR, Kuhn RJ, Diamond MS, Rossmann MG. Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354. Proceedings of the National Academy of Sciences of the United States of America. 107: 18950-5. PMID 20956322 DOI: 10.1073/Pnas.1011036107 |
0.409 |
|
| 2010 |
Heaton NS, Perera R, Berger KL, Khadka S, Lacount DJ, Kuhn RJ, Randall G. Dengue virus nonstructural protein 3 redistributes fatty acid synthase to sites of viral replication and increases cellular fatty acid synthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 17345-50. PMID 20855599 DOI: 10.1073/Pnas.1010811107 |
0.652 |
|
| 2010 |
Junjhon J, Edwards TJ, Utaipat U, Bowman VD, Holdaway HA, Zhang W, Keelapang P, Puttikhunt C, Perera R, Chipman PR, Kasinrerk W, Malasit P, Kuhn RJ, Sittisombut N. Influence of pr-M cleavage on the heterogeneity of extracellular dengue virus particles. Journal of Virology. 84: 8353-8. PMID 20519400 DOI: 10.1128/Jvi.00696-10 |
0.66 |
|
| 2010 |
Kaufmann B, Plevka P, Kuhn RJ, Rossmann MG. Crystallization and preliminary X-ray diffraction analysis of West Nile virus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 558-62. PMID 20445259 DOI: 10.1107/S1744309110009899 |
0.362 |
|
| 2009 |
Kaufmann B, Chipman PR, Holdaway HA, Johnson S, Fremont DH, Kuhn RJ, Diamond MS, Rossmann MG. Capturing a flavivirus pre-fusion intermediate. Plos Pathogens. 5: e1000672. PMID 19956725 DOI: 10.1371/Journal.Ppat.1000672 |
0.354 |
|
| 2009 |
Jose J, Snyder JE, Kuhn RJ. A structural and functional perspective of alphavirus replication and assembly. Future Microbiology. 4: 837-56. PMID 19722838 DOI: 10.2217/fmb.09.59 |
0.484 |
|
| 2009 |
Cherrier MV, Kaufmann B, Nybakken GE, Lok SM, Warren JT, Chen BR, Nelson CA, Kostyuchenko VA, Holdaway HA, Chipman PR, Kuhn RJ, Diamond MS, Rossmann MG, Fremont DH. Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody. The Embo Journal. 28: 3269-76. PMID 19713934 DOI: 10.1038/Emboj.2009.245 |
0.316 |
|
| 2009 |
Patkar CG, Larsen M, Owston M, Smith JL, Kuhn RJ. Identification of inhibitors of yellow fever virus replication using a replicon-based high-throughput assay. Antimicrobial Agents and Chemotherapy. 53: 4103-14. PMID 19651907 DOI: 10.1128/Aac.00074-09 |
0.797 |
|
| 2009 |
Rubach JK, Wasik BR, Rupp JC, Kuhn RJ, Hardy RW, Smith JL. Characterization of purified Sindbis virus nsP4 RNA-dependent RNA polymerase activity in vitro. Virology. 384: 201-8. PMID 19036396 DOI: 10.1016/J.Virol.2008.10.030 |
0.301 |
|
| 2008 |
Zhou Z, Khaliq M, Suk JE, Patkar C, Li L, Kuhn RJ, Post CB. Antiviral compounds discovered by virtual screening of small-molecule libraries against dengue virus E protein. Acs Chemical Biology. 3: 765-75. PMID 19053243 DOI: 10.1021/Cb800176T |
0.832 |
|
| 2008 |
Perera R, Kuhn RJ. Structural proteomics of dengue virus. Current Opinion in Microbiology. 11: 369-77. PMID 18644250 DOI: 10.1016/j.mib.2008.06.004 |
0.727 |
|
| 2008 |
Li Z, Khaliq M, Zhou Z, Post CB, Kuhn RJ, Cushman M. Design, synthesis, and biological evaluation of antiviral agents targeting flavivirus envelope proteins. Journal of Medicinal Chemistry. 51: 4660-71. PMID 18610998 DOI: 10.1021/Jm800412D |
0.414 |
|
| 2008 |
Perera R, Khaliq M, Kuhn RJ. Closing the door on flaviviruses: entry as a target for antiviral drug design. Antiviral Research. 80: 11-22. PMID 18585795 DOI: 10.1016/j.antiviral.2008.05.004 |
0.722 |
|
| 2008 |
Mayuri, Geders TW, Smith JL, Kuhn RJ. Role for conserved residues of sindbis virus nonstructural protein 2 methyltransferase-like domain in regulation of minus-strand synthesis and development of cytopathic infection. Journal of Virology. 82: 7284-97. PMID 18495773 DOI: 10.1128/Jvi.00224-08 |
0.417 |
|
| 2008 |
Li L, Lok SM, Yu IM, Zhang Y, Kuhn RJ, Chen J, Rossmann MG. The flavivirus precursor membrane-envelope protein complex: structure and maturation. Science (New York, N.Y.). 319: 1830-4. PMID 18369147 DOI: 10.1126/Science.1153263 |
0.431 |
|
| 2008 |
Warrier R, Linger BR, Golden BL, Kuhn RJ. Role of sindbis virus capsid protein region II in nucleocapsid core assembly and encapsidation of genomic RNA. Journal of Virology. 82: 4461-70. PMID 18305029 DOI: 10.1128/Jvi.01936-07 |
0.809 |
|
| 2008 |
Lok SM, Kostyuchenko V, Nybakken GE, Holdaway HA, Battisti AJ, Sukupolvi-Petty S, Sedlak D, Fremont DH, Chipman PR, Roehrig JT, Diamond MS, Kuhn RJ, Rossmann MG. Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nature Structural & Molecular Biology. 15: 312-7. PMID 18264114 DOI: 10.1038/Nsmb.1382 |
0.459 |
|
| 2008 |
Chang WS, Shang H, Perera RM, Lok SM, Sedlak D, Kuhn RJ, Lee GU. Rapid detection of dengue virus in serum using magnetic separation and fluorescence detection. The Analyst. 133: 233-40. PMID 18227947 DOI: 10.1039/b710997k |
0.639 |
|
| 2008 |
Patkar CG, Kuhn RJ. Yellow Fever virus NS3 plays an essential role in virus assembly independent of its known enzymatic functions. Journal of Virology. 82: 3342-52. PMID 18199634 DOI: 10.1128/JVI.02447-07 |
0.844 |
|
| 2007 |
van der Schaar HM, Rust MJ, Waarts BL, van der Ende-Metselaar H, Kuhn RJ, Wilschut J, Zhuang X, Smit JM. Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking. Journal of Virology. 81: 12019-28. PMID 17728239 DOI: 10.1128/Jvi.00300-07 |
0.384 |
|
| 2007 |
Patkar CG, Jones CT, Chang YH, Warrier R, Kuhn RJ. Functional requirements of the yellow fever virus capsid protein. Journal of Virology. 81: 6471-81. PMID 17526891 DOI: 10.1128/JVI.02120-6 |
0.805 |
|
| 2007 |
Zhang Y, Kaufmann B, Chipman PR, Kuhn RJ, Rossmann MG. Structure of immature West Nile virus. Journal of Virology. 81: 6141-5. PMID 17376919 DOI: 10.1128/Jvi.00037-07 |
0.407 |
|
| 2007 |
Bera AK, Kuhn RJ, Smith JL. Functional characterization of cis and trans activity of the Flavivirus NS2B-NS3 protease. The Journal of Biological Chemistry. 282: 12883-92. PMID 17337448 DOI: 10.1074/Jbc.M611318200 |
0.45 |
|
| 2007 |
Navaratnarajah CK, Kuhn RJ. Functional characterization of the Sindbis virus E2 glycoprotein by transposon linker-insertion mutagenesis. Virology. 363: 134-47. PMID 17306321 DOI: 10.1016/j.virol.2007.01.006 |
0.789 |
|
| 2007 |
Kim HY, Kuhn RJ, Patkar C, Warrier R, Cushman M. Synthesis of dioxane-based antiviral agents and evaluation of their biological activities as inhibitors of Sindbis virus replication. Bioorganic & Medicinal Chemistry. 15: 2667-79. PMID 17287124 DOI: 10.1016/J.Bmc.2007.01.040 |
0.796 |
|
| 2007 |
Boudko SP, Kuhn RJ, Rossmann MG. The coiled-coil domain structure of the Sin Nombre virus nucleocapsid protein. Journal of Molecular Biology. 366: 1538-44. PMID 17222867 DOI: 10.1016/J.Jmb.2006.12.046 |
0.386 |
|
| 2006 |
Patkar CG, Kuhn RJ. Development of novel antivirals against flaviviruses. Novartis Foundation Symposium. 277: 41-52; discussion 52. PMID 17319153 |
0.815 |
|
| 2006 |
Tomar S, Hardy RW, Smith JL, Kuhn RJ. Catalytic core of alphavirus nonstructural protein nsP4 possesses terminal adenylyltransferase activity. Journal of Virology. 80: 9962-9. PMID 17005674 DOI: 10.1128/Jvi.01067-06 |
0.664 |
|
| 2006 |
Hong EM, Perera R, Kuhn RJ. Alphavirus capsid protein helix I controls a checkpoint in nucleocapsid core assembly. Journal of Virology. 80: 8848-55. PMID 16940497 DOI: 10.1128/JVI.00619-06 |
0.793 |
|
| 2006 |
Kaufmann B, Nybakken GE, Chipman PR, Zhang W, Diamond MS, Fremont DH, Kuhn RJ, Rossmann MG. West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody. Proceedings of the National Academy of Sciences of the United States of America. 103: 12400-4. PMID 16895988 DOI: 10.1073/Pnas.0603488103 |
0.329 |
|
| 2006 |
Mukhopadhyay S, Zhang W, Gabler S, Chipman PR, Strauss EG, Strauss JH, Baker TS, Kuhn RJ, Rossmann MG. Mapping the structure and function of the E1 and E2 glycoproteins in alphaviruses. Structure (London, England : 1993). 14: 63-73. PMID 16407066 DOI: 10.1016/J.Str.2005.07.025 |
0.583 |
|
| 2005 |
Kuhn RJ, Rossmann MG. Structure and assembly of icosahedral enveloped RNA viruses. Advances in Virus Research. 64: 263-84. PMID 16139597 DOI: 10.1016/S0065-3527(05)64008-0 |
0.323 |
|
| 2005 |
Wu J, Bera AK, Kuhn RJ, Smith JL. Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing. Journal of Virology. 79: 10268-77. PMID 16051820 DOI: 10.1128/Jvi.79.16.10268-10277.2005 |
0.41 |
|
| 2005 |
Xiao C, Bator-Kelly CM, Rieder E, Chipman PR, Craig A, Kuhn RJ, Wimmer E, Rossmann MG. The crystal structure of coxsackievirus A21 and its interaction with ICAM-1. Structure (London, England : 1993). 13: 1019-33. PMID 16004874 DOI: 10.1016/J.Str.2005.04.011 |
0.436 |
|
| 2005 |
Kim HY, Patkar C, Warrier R, Kuhn R, Cushman M. Design, synthesis, and evaluation of dioxane-based antiviral agents targeted against the Sindbis virus capsid protein. Bioorganic & Medicinal Chemistry Letters. 15: 3207-11. PMID 15927464 DOI: 10.1016/J.Bmcl.2005.05.013 |
0.801 |
|
| 2005 |
Wilkinson TA, Tellinghuisen TL, Kuhn RJ, Post CB. Association of sindbis virus capsid protein with phospholipid membranes and the E2 glycoprotein: implications for alphavirus assembly. Biochemistry. 44: 2800-10. PMID 15723524 DOI: 10.1021/Bi0479961 |
0.785 |
|
| 2005 |
Zhang W, Heil M, Kuhn RJ, Baker TS. Heparin binding sites on Ross River virus revealed by electron cryo-microscopy. Virology. 332: 511-8. PMID 15680416 DOI: 10.1016/J.Virol.2004.11.043 |
0.805 |
|
| 2005 |
Jones CT, Patkar CG, Kuhn RJ. Construction and applications of yellow fever virus replicons. Virology. 331: 247-59. PMID 15629769 DOI: 10.1016/j.virol.2004.10.034 |
0.822 |
|
| 2005 |
Mukhopadhyay S, Kuhn RJ, Rossmann MG. A structural perspective of the flavivirus life cycle. Nature Reviews. Microbiology. 3: 13-22. PMID 15608696 DOI: 10.1038/Nrmicro1067 |
0.352 |
|
| 2004 |
Choi KH, Groarke JM, Young DC, Rossmann MG, Pevear DC, Kuhn RJ, Smith JL. Design, expression, and purification of a Flaviviridae polymerase using a high-throughput approach to facilitate crystal structure determination. Protein Science : a Publication of the Protein Society. 13: 2685-92. PMID 15388860 DOI: 10.1110/Ps.04872204 |
0.341 |
|
| 2004 |
Zhang Y, Zhang W, Ogata S, Clements D, Strauss JH, Baker TS, Kuhn RJ, Rossmann MG. Conformational changes of the flavivirus E glycoprotein. Structure (London, England : 1993). 12: 1607-18. PMID 15341726 DOI: 10.1016/J.Str.2004.06.019 |
0.62 |
|
| 2004 |
Menon EL, Perera R, Navarro M, Kuhn RJ, Morrison H. Phototoxicity against tumor cells and Sindbis virus by an octahedral rhodium bisbipyridyl complex and evidence for the genome as a target in viral photoinactivation. Inorganic Chemistry. 43: 5373-81. PMID 15310216 DOI: 10.1021/Ic0498586 |
0.652 |
|
| 2004 |
Ma L, Jones CT, Groesch TD, Kuhn RJ, Post CB. Solution structure of dengue virus capsid protein reveals another fold. Proceedings of the National Academy of Sciences of the United States of America. 101: 3414-9. PMID 14993605 DOI: 10.1073/Pnas.0305892101 |
0.389 |
|
| 2004 |
Linger BR, Kunovska L, Kuhn RJ, Golden BL. Sindbis virus nucleocapsid assembly: RNA folding promotes capsid protein dimerization. Rna (New York, N.Y.). 10: 128-38. PMID 14681591 DOI: 10.1261/Rna.5127104 |
0.37 |
|
| 2003 |
Menon EL, Perera R, Kuhn RJ, Morrison H. Reactive oxygen species formation by UV-A irradiation of urocanic acid and the role of trace metals in this chemistry. Photochemistry and Photobiology. 78: 567-75. PMID 14743864 DOI: 10.1562/0031-8655(2003)078<0567:Rosfbu>2.0.Co;2 |
0.568 |
|
| 2003 |
Mukhopadhyay S, Kim BS, Chipman PR, Rossmann MG, Kuhn RJ. Structure of West Nile virus. Science (New York, N.Y.). 302: 248. PMID 14551429 DOI: 10.1126/Science.1089316 |
0.373 |
|
| 2003 |
Zhang W, Chipman PR, Corver J, Johnson PR, Zhang Y, Mukhopadhyay S, Baker TS, Strauss JH, Rossmann MG, Kuhn RJ. Visualization of membrane protein domains by cryo-electron microscopy of dengue virus. Nature Structural Biology. 10: 907-12. PMID 14528291 DOI: 10.1038/Nsb990 |
0.642 |
|
| 2003 |
Kuhn RJ, Strauss JH. Enveloped viruses. Advances in Protein Chemistry. 64: 363-77. PMID 13677053 |
0.67 |
|
| 2003 |
Perera R, Navaratnarajah C, Kuhn RJ. A heterologous coiled coil can substitute for helix I of the Sindbis virus capsid protein. Journal of Virology. 77: 8345-53. PMID 12857904 DOI: 10.1128/JVI.77.15.8345-8353.2003 |
0.841 |
|
| 2003 |
Zhang Y, Corver J, Chipman PR, Zhang W, Pletnev SV, Sedlak D, Baker TS, Strauss JH, Kuhn RJ, Rossmann MG. Structures of immature flavivirus particles. The Embo Journal. 22: 2604-13. PMID 12773377 DOI: 10.1093/Emboj/Cdg270 |
0.623 |
|
| 2003 |
Jones CT, Ma L, Burgner JW, Groesch TD, Post CB, Kuhn RJ. Flavivirus capsid is a dimeric alpha-helical protein. Journal of Virology. 77: 7143-9. PMID 12768036 DOI: 10.1128/Jvi.77.12.7143-7149.2003 |
0.365 |
|
| 2003 |
He Y, Mueller S, Chipman PR, Bator CM, Peng X, Bowman VD, Mukhopadhyay S, Wimmer E, Kuhn RJ, Rossmann MG. Complexes of poliovirus serotypes with their common cellular receptor, CD155. Journal of Virology. 77: 4827-35. PMID 12663789 DOI: 10.1128/Jvi.77.8.4827-4835.2003 |
0.608 |
|
| 2002 |
Zhang W, Mukhopadhyay S, Pletnev SV, Baker TS, Kuhn RJ, Rossmann MG. Placement of the structural proteins in Sindbis virus. Journal of Virology. 76: 11645-58. PMID 12388725 DOI: 10.1128/Jvi.76.22.11645-11658.2002 |
0.392 |
|
| 2002 |
Mukhopadhyay S, Chipman PR, Hong EM, Kuhn RJ, Rossmann MG. In vitro-assembled alphavirus core-like particles maintain a structure similar to that of nucleocapsid cores in mature virus Journal of Virology. 76: 11128-11132. PMID 12368355 DOI: 10.1128/Jvi.76.21.11128-11132.2002 |
0.808 |
|
| 2002 |
Zhang W, Fisher BR, Olson NH, Strauss JH, Kuhn RJ, Baker TS. Aura virus structure suggests that the T=4 organization is a fundamental property of viral structural proteins. Journal of Virology. 76: 7239-46. PMID 12072523 DOI: 10.1128/Jvi.76.14.7239-7246.2002 |
0.692 |
|
| 2002 |
Kuhn RJ, Zhang W, Rossmann MG, Pletnev SV, Corver J, Lenches E, Jones CT, Mukhopadhyay S, Chipman PR, Strauss EG, Baker TS, Strauss JH. Structure of dengue virus: implications for flavivirus organization, maturation, and fusion. Cell. 108: 717-25. PMID 11893341 DOI: 10.1016/S0092-8674(02)00660-8 |
0.621 |
|
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