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Snorri Thor Sigurdsson - Publications

Affiliations: 
Chemistry University of Iceland, Reykjavík, Iceland 
Area:
chemistry and structural biology of nucleic acids
Website:
https://notendur.hi.is/~snorrisi/

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Segler AJ, Sigurdsson ST. A Carbazole-Derived Nitroxide That Is an Analogue of Cytidine: A Rigid Spin Label for DNA and RNA. The Journal of Organic Chemistry. 86: 11647-11659. PMID 34410721 DOI: 10.1021/acs.joc.1c01176  0.344
2020 Collauto A, von Bülow S, Gophane D, Saha S, Stelzl L, Hummer G, Sigurdsson ST, Prisner T. Compaction of RNA duplexes in the cell. Angewandte Chemie (International Ed. in English). PMID 32804430 DOI: 10.1002/Anie.202009800  0.372
2020 Juliusson HY, Sigurdsson ST. Reduction Resistant and Rigid Nitroxide Spin-Labels for DNA and RNA. The Journal of Organic Chemistry. 85: 4036-4046. PMID 32103670 DOI: 10.1021/Acs.Joc.9B02988  0.435
2020 Kamble N, Wolfrum M, Halbritter T, Sigurdsson ST, Richert C. Front Cover: Noncovalent Spin‐Labeling of DNA and RNA Triplexes (C&B 2/2020) Chemistry & Biodiversity. 17. DOI: 10.1002/Cbdv.202000030  0.391
2019 Richert C, Kamble N, Wolfrum M, Halbritter T, Sigurdsson ST. Noncovalent spin-Labeling of DNA and RNA triplexes. Chemistry & Biodiversity. PMID 31872549 DOI: 10.1002/Cbdv.201900676  0.422
2019 Gustmann H, Segler AJ, Gophane DB, Reuss AJ, Grünewald C, Braun M, Weigand JE, Sigurdsson ST, Wachtveitl J. Structure guided fluorescence labeling reveals a two-step binding mechanism of neomycin to its RNA aptamer. Nucleic Acids Research. 47: 15-28. PMID 30462266 DOI: 10.1093/Nar/Gky1110  0.397
2019 Gophane DB, Endeward B, Prisner TF, Sigurdsson ST. A semi-rigid isoindoline-derived nitroxide spin label for RNA. Organic & Biomolecular Chemistry. 16: 816-824. PMID 29326999 DOI: 10.1039/C7Ob02870A  0.389
2019 Juliusson HY, Segler AJ, Sigurdsson ST. Benzoyl‐Protected Hydroxylamines for Improved Chemical Synthesis of Oligonucleotides Containing Nitroxide Spin Labels European Journal of Organic Chemistry. 2019: 3799-3805. DOI: 10.1002/Ejoc.201900553  0.327
2018 Hetzke T, Vogel M, Gophane DB, Weigand JE, Suess B, Sigurdsson ST, Prisner TF. Influence of Mg on the conformational flexibility of a tetracycline aptamer. Rna (New York, N.Y.). 25: 158-167. PMID 30337459 DOI: 10.1261/Rna.068684.118  0.415
2018 Saha S, Hetzke T, Prisner TF, Sigurdsson ST. Noncovalent spin-labeling of RNA: the aptamer approach. Chemical Communications (Cambridge, England). PMID 30276367 DOI: 10.1039/C8Cc05597A  0.386
2018 Mentink-Vigier F, Marin-Montesinos I, Jagtap AP, Halbritter T, Van Tol J, Hediger S, Lee D, Sigurdsson ST, De Paëpe G. Computationally-assisted design of polarizing agents for dynamic nuclear polarization enhanced NMR: the AsymPol family. Journal of the American Chemical Society. PMID 30095255 DOI: 10.1021/Jacs.8B04911  0.308
2018 Albert BJ, Gao C, Sesti EL, Saliba EP, Alaniva N, Scott FJ, Sigurdsson ST, Barnes AB. Dynamic Nuclear Polarization NMR in Human Cells Using Fluorescent Polarizing Agents. Biochemistry. PMID 29924582 DOI: 10.1021/Acs.Biochem.8B00257  0.307
2018 Gränz M, Erlenbach N, Spindler P, Gophane DB, Stelzl LS, Sigurdsson ST, Prisner TF. Dynamics of Nucleic Acids at Room Temperature Revealed by Pulsed EPR Spectroscopy. Angewandte Chemie (International Ed. in English). 57: 10540-10543. PMID 29858557 DOI: 10.1002/Anie.201803682  0.342
2018 Geiger M, Jagtap A, Kaushik M, Sun H, Stöppler D, Sigurdsson S, Corzilius B, Oschkinat H. Efficiency of water-soluble nitroxide biradicals for dynamic nuclear polarization in rotating solids at 9.4 T: bcTol-M and cyolyl-TOTAPOL as new polarizing agents. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29741214 DOI: 10.1002/Chem.201801251  0.304
2018 Kamble NR, Sigurdsson ST. Purine-Derived Nitroxides for Noncovalent Spin-Labeling of Abasic Sites in Duplex Nucleic Acids. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29451325 DOI: 10.1002/Chem.201705410  0.462
2018 Kamble NR, Gränz M, Prisner TF, Sigurdsson ST. Noncovalent and site-directed spin labeling of duplex RNA. Chemical Communications (Cambridge, England). 52: 14442-14445. PMID 27901530 DOI: 10.1039/C6Cc08387K  0.418
2017 Grytz CM, Kazemi S, Marko A, Cekan P, Güntert P, Sigurdsson ST, Prisner TF. Determination of helix orientations in a flexible DNA by multi-frequency EPR spectroscopy. Physical Chemistry Chemical Physics : Pccp. PMID 29090294 DOI: 10.1039/C7Cp04997H  0.311
2017 Gustmann H, Lefrancois D, Reuss AJ, Gophane DB, Braun M, Dreuw A, Sigurdsson ST, Wachtveitl J. Spin the light off: rapid internal conversion into a dark doublet state quenches the fluorescence of an RNA spin label. Physical Chemistry Chemical Physics : Pccp. 19: 26255-26264. PMID 28933471 DOI: 10.1039/C7Cp03975A  0.349
2016 Stöppler D, Song C, van Rossum BJ, Geiger MA, Lang C, Mroginski MA, Pandurang Jagtap A, Sigurdsson ST, Matysik J, Hughes J, Oschkinat H. Dynamic Nuclear Polarization Provides New Insights into Chromophore Structure in Phytochrome Photoreceptors. Angewandte Chemie (International Ed. in English). PMID 27879035 DOI: 10.1002/Anie.201608119  0.31
2015 Saha S, Jagtap AP, Sigurdsson ST. Site-Directed Spin Labeling of RNA by Postsynthetic Modification of 2'-Amino Groups. Methods in Enzymology. 563: 397-414. PMID 26478493 DOI: 10.1016/Bs.Mie.2015.07.017  0.401
2015 Saha S, Jagtap AP, Sigurdsson ST. Site-directed spin labeling of 2'-amino groups in RNA with isoindoline nitroxides that are resistant to reduction. Chemical Communications (Cambridge, England). 51: 13142-5. PMID 26192344 DOI: 10.1039/C5Cc05014F  0.403
2015 Kaminker I, Bye M, Mendelman N, Gislason K, Sigurdsson ST, Goldfarb D. Correction: Distance measurements between manganese(ii) and nitroxide spin-labels by DEER determine a binding site of Mn(2+) in the HP92 loop of ribosomal RNA. Physical Chemistry Chemical Physics : Pccp. 17: 18197. PMID 26083789 DOI: 10.1039/C5Cp90106E  0.365
2015 Gophane DB, Sigurdsson ST. TEMPO-derived spin labels linked to the nucleobases adenine and cytosine for probing local structural perturbations in DNA by EPR spectroscopy. Beilstein Journal of Organic Chemistry. 11: 219-27. PMID 25815073 DOI: 10.3762/Bjoc.11.24  0.352
2015 Gutmann T, Liu J, Rothermel N, Xu Y, Jaumann E, Werner M, Breitzke H, Sigurdsson ST, Buntkowsky G. Natural abundance 15N NMR by dynamic nuclear polarization: fast analysis of binding sites of a novel amine-carboxyl-linked immobilized dirhodium catalyst. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 3798-805. PMID 25620003 DOI: 10.1002/Chem.201405043  0.322
2014 Chalmers BA, Saha S, Nguyen T, McMurtrie J, Sigurdsson ST, Bottle SE, Masters KS. TMIO-PyrImid hybrids are profluorescent, site-directed spin labels for nucleic acids. Organic Letters. 16: 5528-31. PMID 25350496 DOI: 10.1021/Ol502003A  0.424
2014 Gophane DB, Endeward B, Prisner TF, Sigurdsson ST. Conformationally restricted isoindoline-derived spin labels in duplex DNA: distances and rotational flexibility by pulsed electron-electron double resonance spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 15913-9. PMID 25296640 DOI: 10.1002/Chem.201403726  0.405
2014 Shelke SA, Sandholt GB, Sigurdsson ST. Nitroxide-labeled pyrimidines for non-covalent spin-labeling of abasic sites in DNA and RNA duplexes. Organic & Biomolecular Chemistry. 12: 7366-74. PMID 25119508 DOI: 10.1039/C4Ob01095G  0.439
2013 Kunjir NC, Reginsson GW, Schiemann O, Sigurdsson ST. Measurements of short distances between trityl spin labels with CW EPR, DQC and PELDOR Physical Chemistry Chemical Physics. 15: 19673-19685. PMID 24135783 DOI: 10.1039/C3Cp52789A  0.311
2013 Nguyen P, Shi X, Sigurdsson ST, Herschlag D, Qin PZ. A single-stranded junction modulates nanosecond motional ordering of the substrate recognition duplex of a group I ribozyme. Chembiochem : a European Journal of Chemical Biology. 14: 1720-3. PMID 23900919 DOI: 10.1002/Cbic.201300376  0.387
2013 Tkach I, Pornsuwan S, Höbartner C, Wachowius F, Sigurdsson ST, Baranova TY, Diederichsen U, Sicoli G, Bennati M. Orientation selection in distance measurements between nitroxide spin labels at 94 GHz EPR with variable dual frequency irradiation. Physical Chemistry Chemical Physics : Pccp. 15: 3433-7. PMID 23381580 DOI: 10.1039/C3Cp44415E  0.319
2013 Gophane DB, Sigurdsson ST. Hydrogen-bonding controlled rigidity of an isoindoline-derived nitroxide spin label for nucleic acids Chemical Communications. 49: 999-1001. PMID 23250475 DOI: 10.1039/C2Cc36389E  0.373
2013 Gislason K, Sigurdsson ST. Rigid 5′-6-locked phenanthroline-derived nucleosides chelated to ruthenium and europium ions Bioorganic and Medicinal Chemistry Letters. 23: 264-267. PMID 23177784 DOI: 10.1016/J.Bmcl.2012.10.104  0.32
2013 Gislason K, Gophane DB, Sigurdsson ST. Syntheses and photophysical properties of 5′-6-locked fluorescent nucleosides Organic and Biomolecular Chemistry. 11: 149-157. PMID 23114639 DOI: 10.1039/C2Ob26536B  0.395
2013 Reginsson GW, Shelke SA, Rouillon C, White MF, Sigurdsson ST, Schiemann O. Protein-induced changes in DNA structure and dynamics observed with noncovalent site-directed spin labeling and PELDOR. Nucleic Acids Research. 41: e11. PMID 22941643 DOI: 10.1093/Nar/Gks817  0.434
2012 Reginsson GW, Kunjir NC, Sigurdsson ST, Schiemann O. Trityl radicals: Spin labels for nanometer-distance measurements Chemistry - a European Journal. 18: 13580-13584. PMID 22996284 DOI: 10.1002/Chem.201203014  0.322
2012 Höbartner C, Sicoli G, Wachowius F, Gophane DB, Sigurdsson ST. Synthesis and characterization of RNA containing a rigid and nonperturbing cytidine-derived spin label Journal of Organic Chemistry. 77: 7749-7754. PMID 22881715 DOI: 10.1021/Jo301227W  0.416
2012 Cekan P, Sigurdsson ST. Conformation and dynamics of nucleotides in bulges and symmetric internal loops in duplex DNA studied by EPR and fluorescence spectroscopies Biochemical and Biophysical Research Communications. 420: 656-661. PMID 22450317 DOI: 10.1016/J.Bbrc.2012.03.059  0.386
2012 Shelke SA, Sigurdsson ST. Effect of N3 modifications on the affinity of spin label ç for abasic sites in duplex DNA. Chembiochem : a European Journal of Chemical Biology. 13: 684-90. PMID 22408066 DOI: 10.1002/Cbic.201100728  0.409
2012 Reginsson GW, Hunter RI, Cruickshank PA, Bolton DR, Sigurdsson ST, Smith GM, Schiemann O. W-band PELDOR with 1 kW microwave power: molecular geometry, flexibility and exchange coupling. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 216: 175-82. PMID 22386646 DOI: 10.1016/J.Jmr.2012.01.019  0.307
2012 Shelke SA, Sigurdsson ST. Structural changes of an abasic site in duplex DNA affect noncovalent binding of the spin label ç. Nucleic Acids Research. 40: 3732-40. PMID 22210856 DOI: 10.1093/Nar/Gkr1210  0.422
2012 Shelke SA, Sigurdsson ST. Site-directed spin labelling of nucleic acids European Journal of Organic Chemistry. 2291-2301. DOI: 10.1002/Ejoc.201101434  0.36
2011 Flosadóttir HD, Jónsson H, Sigurdsson ST, Ingólfsson O. Experimental and theoretical study of the metastable decay of negatively charged nucleosides in the gas phase Physical Chemistry Chemical Physics. 13: 15283-15290. PMID 21769360 DOI: 10.1039/C1Cp21298B  0.356
2011 Marko A, Denysenkov V, Margraf D, Cekan P, Schiemann O, Sigurdsson ST, Prisner TF. Conformational flexibility of DNA Journal of the American Chemical Society. 133: 13375-13379. PMID 21702503 DOI: 10.1021/Ja201244U  0.41
2011 Sezer D, Sigurdsson ST. Simulating electron spin resonance spectra of macromolecules labeled with two dipolar-coupled nitroxide spin labels from trajectories. Physical Chemistry Chemical Physics : Pccp. 13: 12785-97. PMID 21691643 DOI: 10.1039/C1Cp20430K  0.376
2011 Edwards TE, Cekan P, Reginsson GW, Shelke SA, Ferré-D'Amaré AR, Schiemann O, Sigurdsson ST. Crystal structure of a DNA containing the planar, phenoxazine-derived bi-functional spectroscopic probe C. Nucleic Acids Research. 39: 4419-26. PMID 21252294 DOI: 10.1093/Nar/Gkr015  0.613
2011 Sigurdsson ST. Nitroxides and nucleic acids: Chemistry and electron paramagnetic resonance (EPR) spectroscopy Pure and Applied Chemistry. 83: 677-686. DOI: 10.1351/Pac-Con-10-09-28  0.385
2010 Shelke SA, Sigurdsson ST. Noncovalent and site-directed spin labeling of nucleic acids. Angewandte Chemie (International Ed. in English). 49: 7984-6. PMID 20845340 DOI: 10.1002/Anie.201002637  0.346
2010 Jakobsen U, Shelke SA, Vogel S, Sigurdsson ST. Site-directed spin-labeling of nucleic acids by click chemistry: detection of abasic sites in duplex DNA by EPR spectroscopy. Journal of the American Chemical Society. 132: 10424-8. PMID 20617829 DOI: 10.1021/Ja102797K  0.392
2010 Marko A, Margraf D, Cekan P, Sigurdsson ST, Schiemann O, Prisner TF. Analytical method to determine the orientation of rigid spin labels in DNA. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 81: 021911. PMID 20365599 DOI: 10.1103/Physreve.81.021911  0.336
2010 Gislason K, Sigurdsson ST. Synthesis of a 5′-6-locked, 1,10-phenanthroline-containing nucleoside and its incorporation into DNA European Journal of Organic Chemistry. 4713-4718. DOI: 10.1002/Ejoc.201000370  0.427
2009 Zhang X, Cekan P, Sigurdsson ST, Qin PZ. Studying RNA using site-directed spin-labeling and continuous-wave electron paramagnetic resonance spectroscopy. Methods in Enzymology. 469: 303-328. PMID 20946796 DOI: 10.1016/S0076-6879(09)69015-7  0.411
2009 Cekan P, Sigurdsson ST. Identification of single-base mismatches in duplex DNA by EPR spectroscopy. Journal of the American Chemical Society. 131: 18054-6. PMID 19928915 DOI: 10.1021/Ja905623K  0.318
2009 Smith AL, Cekan P, Brewood GP, Okonogi TM, Alemayehu S, Hustedt EJ, Benight AS, Sigurdsson ST, Robinson BH. Conformational equilibria of bulged sites in duplex DNA studied by EPR spectroscopy. The Journal of Physical Chemistry. B. 113: 2664-75. PMID 19708106 DOI: 10.1021/Jp808260B  0.42
2009 Cekan P, Jonsson EO, Sigurdsson ST. Folding of the cocaine aptamer studied by EPR and fluorescence spectroscopies using the bifunctional spectroscopic probe Ç. Nucleic Acids Research. 37: 3990-5. PMID 19406921 DOI: 10.1093/Nar/Gkp277  0.308
2009 Heidarsson PO, Sigurdsson ST, Ásgeirsson B. Structural features and dynamics of a cold-adapted alkaline phosphatase studied by EPR spectroscopy Febs Journal. 276: 2725-2735. PMID 19368558 DOI: 10.1111/J.1742-4658.2009.06996.X  0.373
2009 Schiemann O, Cekan P, Margraf D, Prisner TF, Sigurdsson ST. Relative orientation of rigid nitroxides by peldor: Beyond distance measurements in nucleic acids Angewandte Chemie - International Edition. 48: 3292-3295. PMID 19322852 DOI: 10.1002/Anie.200805152  0.348
2009 Robinson B, Smith AL, Chekan P, Brewood G, Okonogi TM, Alemayehu S, Hustedt EJ, Benight AS, Sigurdsson ST. Conformational Equilibria Of Bulged Sites In Duplex Dna Studied By EPR Spectroscopy And Differential Scanning Calorimetry Biophysical Journal. 96: 346a. DOI: 10.1016/J.Bpj.2008.12.1738  0.432
2008 Cekan P, Smith AL, Barhate N, Robinson BH, Sigurdsson ST. Rigid spin-labeled nucleoside C: a nonperturbing EPR probe of nucleic acid conformation. Nucleic Acids Research. 36: 5946-54. PMID 18805908 DOI: 10.1093/Nar/Gkn562  0.424
2008 Cekan P, Sigurdsson ST. Single base interrogation by a fluorescent nucleotide: each of the four DNA bases identified by fluorescence spectroscopy. Chemical Communications (Cambridge, England). 3393-5. PMID 18633500 DOI: 10.1039/B801833B  0.384
2008 Smith AL, Cekan P, Rangel DP, Sigurdsson ST, Mailer C, Robinson BH. Theory for spin-lattice relaxation of spin probes on weakly deformable DNA. The Journal of Physical Chemistry. B. 112: 9219-36. PMID 18593148 DOI: 10.1021/Jp7111704  0.364
2008 Barhate NB, Barhate RN, Cekan P, Drobny G, Sigurdsson ST. A nonafluoro nucleoside as a sensitive 19f NMR probe of nucleic acid conformation. Organic Letters. 10: 2745-7. PMID 18533676 DOI: 10.1021/Ol800872A  0.374
2007 Edwards TE, Sigurdsson ST. Site-specific incorporation of nitroxide spin-labels into 2'-positions of nucleic acids. Nature Protocols. 2: 1954-62. PMID 17703207 DOI: 10.1038/Nprot.2007.273  0.603
2007 Barhate N, Cekan P, Massey AP, Sigurdsson ST. A nucleoside that contains a rigid nitroxide spin label: a fluorophore in disguise. Angewandte Chemie (International Ed. in English). 46: 2655-8. PMID 17309085 DOI: 10.1002/Anie.200603993  0.32
2007 Barhate N, Cekan P, Massey AP, Sigurdsson ST. A Rigid Nitroxide Spin Label Synfacts. 2007: 704-704. DOI: 10.1055/S-2007-968655  0.301
2007 Barhate N, Cekan P, Massey AP, Sigurdsson ST. Inside Cover: A Nucleoside That Contains a Rigid Nitroxide Spin Label: A Fluorophore in Disguise (Angew. Chem. Int. Ed. 15/2007) Angewandte Chemie. 46: 2546-2546. DOI: 10.1002/Anie.200790057  0.317
2007 Barhate N, Cekan P, Massey AP, Sigurdsson ST. Innentitelbild: A Nucleoside That Contains a Rigid Nitroxide Spin Label: A Fluorophore in Disguise (Angew. Chem. 15/2007) Angewandte Chemie. 119: 2598-2598. DOI: 10.1002/Ange.200790057  0.321
2006 Louie EA, Chirakul P, Raghunathan V, Sigurdsson ST, Drobny GP. Using solid-state 31P{19F} REDOR NMR to measure distances between a trifluoromethyl group and a phosphodiester in nucleic acids. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 178: 11-24. PMID 16213170 DOI: 10.1016/J.Jmr.2005.06.018  0.35
2005 Edwards TE, Sigurdsson ST. EPR spectroscopic analysis of U7 hammerhead ribozyme dynamics during metal ion induced folding. Biochemistry. 44: 12870-8. PMID 16171402 DOI: 10.1021/Bi050549G  0.569
2005 Olsen GL, Edwards TE, Deka P, Varani G, Sigurdsson ST, Drobny GP. Monitoring tat peptide binding to TAR RNA by solid-state 31P-19F REDOR NMR. Nucleic Acids Research. 33: 3447-54. PMID 15961729 DOI: 10.1093/Nar/Gki626  0.59
2005 Edwards TE, Robinson BH, Sigurdsson ST. Identification of amino acids that promote specific and rigid TAR RNA-tat protein complex formation. Chemistry & Biology. 12: 329-37. PMID 15797217 DOI: 10.1016/J.Chembiol.2005.01.012  0.588
2005 Borda EJ, Sigurdsson ST. Investigation of Mg2+- and temperature-dependent folding of the hairpin ribozyme by photo-crosslinking: Effects of photo-crosslinker tether length and chemistry Nucleic Acids Research. 33: 1058-1068. PMID 15722480 DOI: 10.1093/Nar/Gki237  0.769
2005 Blondal T, Thorisdottir A, Unnsteinsdottir U, Hjorleifsdottir S, Aevarsson A, Ernstsson S, Fridjonsson OH, Skirnisdottir S, Wheat JO, Hermannsdottir AG, Sigurdsson ST, Hreggvidsson GO, Smith AV, Kristjansson JK. Isolation and characterization of a thermostable RNA ligase 1 from a Thermus scotoductus bacteriophage TS2126 with good single-stranded DNA ligation properties. Nucleic Acids Research. 33: 135-42. PMID 15642699 DOI: 10.1093/Nar/Gki149  0.408
2005 Cekan P, Sigurdsson ST. Spin labeled nucleic acids for EPR spectroscopic study of DNA and RNA structure and function Collection of Czechoslovak Chemical Communications. 7: 225-228. DOI: 10.1135/Css200507225  0.449
2004 Leulliot N, Quevillon-Cheruel S, Graille M, van Tilbeurgh H, Leeper TC, Godin KS, Edwards TE, Sigurdsson ST, Rozenkrants N, Nagel RJ, Ares M, Varani G. A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III. The Embo Journal. 23: 2468-77. PMID 15192703 DOI: 10.1038/Sj.Emboj.7600260  0.565
2004 Edfeldt NB, Harwood EA, Sigurdsson ST, Hopkins PB, Reid BR. Sequence context effect on the structure of nitrous acid induced DNA interstrand cross-links. Nucleic Acids Research. 32: 2795-801. PMID 15155848 DOI: 10.1093/Nar/Gkh607  0.627
2004 Edfeldt NB, Harwood EA, Sigurdsson ST, Hopkins PB, Reid BR. Solution structure of a nitrous acid induced DNA interstrand cross-link. Nucleic Acids Research. 32: 2785-94. PMID 15155847 DOI: 10.1093/Nar/Gkh606  0.641
2004 Massey AP, Sigurdsson ST. Chemical syntheses of inhibitory substrates of the RNA-RNA ligation reaction catalyzed by the hairpin ribozyme. Nucleic Acids Research. 32: 2017-22. PMID 15064361 DOI: 10.1093/Nar/Gkh517  0.368
2004 Borda EJ, Sigurdsson ST. Interactions of the antibiotics neomycin B and chlortetracycline with the hammerhead ribozyme as studied by Zn2+-dependent RNA cleavage Bioorganic and Medicinal Chemistry. 12: 1023-1028. PMID 14980615 DOI: 10.1016/J.Bmc.2003.12.004  0.756
2003 Schiemann O, Fritscher J, Kisseleva N, Sigurdsson ST, Prisner TF. Structural investigation of a high-affinity MnII binding site in the hammerhead ribozyme by EPR spectroscopy and DFT calculations. Effects of neomycin B on metal-ion binding. Chembiochem : a European Journal of Chemical Biology. 4: 1057-65. PMID 14523924 DOI: 10.1002/Cbic.200300653  0.346
2003 Olsen GL, Louie EA, Drobny GP, Sigurdsson ST. Determination of DNA minor groove width in distamycin-DNA complexes by solid-state NMR. Nucleic Acids Research. 31: 5084-9. PMID 12930959 DOI: 10.1093/Nar/Gkg720  0.36
2003 Borda EJ, Markley JC, Sigurdsson ST. Zinc-dependent cleavage in the catalytic core of the hammerhead ribozyme: Evidence for a pH-dependent conformational change Nucleic Acids Research. 31: 2595-2600. PMID 12736309 DOI: 10.1093/Nar/Gkg349  0.764
2003 Edwards TE, Sigurdsson ST. EPR spectroscopic analysis of TAR RNA-metal ion interactions. Biochemical and Biophysical Research Communications. 303: 721-5. PMID 12659878 DOI: 10.1016/S0006-291X(03)00411-X  0.589
2003 Schiemann O, Weber A, Edwards TE, Prisner TF, Sigurdsson ST. Nanometer distance measurements on RNA using PELDOR Journal of the American Chemical Society. 125: 3434-3435. PMID 12643697 DOI: 10.1021/Ja0274610  0.596
2003 Chirakul P, Sigurdsson ST. Stereospecific syntheses of 3'-deuterated pyrimidine nucleosides and their site-specific incorporation into DNA. Organic Letters. 5: 917-9. PMID 12633105 DOI: 10.1021/Ol034102G  0.361
2002 Edwards TE, Sigurdsson ST. Electron paramagnetic resonance dynamic signatures of TAR RNA-small molecule complexes provide insight into RNA structure and recognition Biochemistry. 41: 14843-14847. PMID 12475232 DOI: 10.1021/Bi026299A  0.617
2002 Rupert PB, Massey AP, Sigurdsson ST, Ferré-D'Amaré AR. Transition state stabilization by a catalytic RNA. Science (New York, N.Y.). 298: 1421-4. PMID 12376595 DOI: 10.1126/Science.1076093  0.363
2002 Edwards TE, Okonogi TM, Sigurdsson ST. Investigation of RNA-protein and RNA-metal ion interactions by electron paramagnetic resonance spectroscopy. The HIV TAR-Tat motif. Chemistry & Biology. 9: 699-706. PMID 12079781 DOI: 10.1016/S1074-5521(02)00150-3  0.608
2001 Markley JC, Godde F, Sigurdsson ST. Identification and characterization of a divalent metal ion-dependent cleavage site in the hammerhead ribozyme. Biochemistry. 40: 13849-56. PMID 11705374 DOI: 10.1021/Bi015634C  0.367
2001 Markley JC, Chirakul P, Sologub D, Sigurdsson ST. Incorporation of 2'-deoxy-5-(trifluoromethyl)uridine and 5-cyano-2'-deoxyuridine into DNA. Bioorganic & Medicinal Chemistry Letters. 11: 2453-5. PMID 11549445 DOI: 10.1016/S0960-894X(01)00461-9  0.364
2001 Edwards TE, Okonogi TM, Robinson BH, Sigurdsson ST. Site-specific incorporation of nitroxide spin-labels into internal sites of the TAR RNA; structure-dependent dynamics of RNA by EPR spectroscopy. Journal of the American Chemical Society. 123: 1527-8. PMID 11456739 DOI: 10.1021/Ja005649I  0.616
2000 Alefelder S, Sigurdsson ST. Interstrand disulfide cross-linking of internal sugar residues in duplex RNA Bioorganic and Medicinal Chemistry. 8: 269-273. PMID 10968286 DOI: 10.1016/S0968-0896(99)00280-1  0.417
2000 Paz MM, Sigurdsson ST, Hopkins PB. Monoalkylation of DNA by reductively activated FR66979. Bioorganic & Medicinal Chemistry. 8: 173-9. PMID 10968276 DOI: 10.1016/S0968-0896(99)00270-9  0.635
2000 Sigurdsson ST. Site-specific sulfhydryl groups for study of RNA conformation via disulfide cross-linking. Methods in Enzymology. 318: 165-75. PMID 10889987 DOI: 10.1016/S0076-6879(00)18051-6  0.388
2000 Harwood EA, Hopkins PB, Sigurdsson ST. Chemical synthesis of cross-link lesions found in nitrous acid treated DNA: a general method for the preparation of N2-substituted 2'-deoxyguanosines. The Journal of Organic Chemistry. 65: 2959-64. PMID 10814184 DOI: 10.1021/Jo991501+  0.627
1999 Luce RA, Sigurdsson ST, Hopkins PB. Quantification of formaldehyde-mediated covalent adducts of adriamycin with DNA. Biochemistry. 38: 8682-90. PMID 10393543 DOI: 10.1021/Bi990553Q  0.62
1999 Sigurdsson ST. Thiol-containing RNA for the study of structure and function of ribozymes. Methods (San Diego, Calif.). 18: 71-7. PMID 10208818 DOI: 10.1006/Meth.1999.0758  0.38
1999 Harwood EA, Sigurdsson ST, Edfeldt NBF, Reid BR, Hopkins PB. Chemical synthesis and preliminary structural characterization of a nitrous acid interstrand cross-linked duplex DNA Journal of the American Chemical Society. 121: 5081-5082. DOI: 10.1021/Ja984426D  0.639
1997 Earnshaw DJ, Masquida B, Müller S, Sigurdsson ST, Eckstein F, Westhof E, Gait MJ. Inter-domain cross-linking and molecular modelling of the hairpin ribozyme. Journal of Molecular Biology. 274: 197-212. PMID 9398527 DOI: 10.1006/Jmbi.1997.1405  0.506
1996 Sigurdsson ST, Seeger B, Kutzke U, Eckstein F. A Mild and Simple Method for the Preparation of Isocyanates from Aliphatic Amines Using Trichloromethyl Chloroformate. Synthesis of an Isocyanate Containing an Activated Disulfide. The Journal of Organic Chemistry. 61: 3883-3884. PMID 11667245 DOI: 10.1021/Jo9521920  0.444
1996 Thomson JB, Sigurdsson ST, Zeuch A, Eckstein F. In vitro selection of hammerhead ribozymes containing a bulged nucleotide in stem II. Nucleic Acids Research. 24: 4401-6. PMID 8948630 DOI: 10.1093/Nar/24.22.4401  0.471
1996 Sigurdsson ST, Eckstein F. Isolation of oligoribonucleotides containing intramolecular cross-links. Analytical Biochemistry. 235: 241-2. PMID 8833336 DOI: 10.1006/Abio.1996.0120  0.46
1996 Fagan PA, Spielmann HP, Sigurdsson S, Rink SM, Hopkins PB, Wemmer DE. An NMR study of [d(CGCGAATTCGCG)]2 containing an interstrand cross-link derived from a distamycin-pyrrole conjugate. Nucleic Acids Research. 24: 1566-73. PMID 8628693 DOI: 10.1093/Nar/24.8.1566  0.654
1996 Schmidt S, Earnshaw DJ, Sigurdsson ST, Eckstein F, Gait MJ. Probing the tertiary structure of the hairpin ribozyme by chemical crosslinking Collection of Czechoslovak Chemical Communications. 61: 276-279. DOI: 10.1135/Cccc1996S276  0.487
1996 Sigurdsson ST, Seeger B, Kutzke U, Eckstein F. A mild and simple method for the preparation of isocyanates from aliphatic amines using trichloromethyl chloroformate. synthesis of an isocyanate containing an activated disulfide Journal of Organic Chemistry. 61: 3883-3884.  0.372
1995 Sigurdsson ST, Eckstein F. Structure-function relationships of hammerhead ribozymes: from understanding to applications. Trends in Biotechnology. 13: 286-9. PMID 7662303 DOI: 10.1016/S0167-7799(00)88966-0  0.521
1995 Sigurdsson ST, Tuschl T, Eckstein F. Probing RNA tertiary structure: interhelical crosslinking of the hammerhead ribozyme. Rna (New York, N.Y.). 1: 575-83. PMID 7489517  0.586
1994 Sigurdsson ST, Hopkins PB. Synthesis and reactions with DNA of a family of DNA-DNA afinity cross-linking agents Tetrahedron. 50: 12065-12084. DOI: 10.1016/S0040-4020(01)89560-0  0.632
1993 Woo J, Sigurdsson ST, Hopkins PB. DNA interstrand cross-linking reactions of pyrrole-derived, bifunctional electrophiles: Evidence for a common target site in DNA Journal of the American Chemical Society. 115: 3407-3415. DOI: 10.1021/Ja00062A002  0.644
1993 Woo J, Sigurdsson ST, Hopkins PB. DNA interstrand cross-linking by reductively activated FR900482 and FR66979 Journal of the American Chemical Society. 115: 1199-1200. DOI: 10.1021/Ja00056A084  0.612
1992 Kirchner JJ, Sigurdsson ST, Hopkins PB. Interstrand cross-linking of duplex DNA by nitrous acid: Covalent structure of the dG-to-dG cross-link at the sequence 5′-CG Journal of the American Chemical Society. 114: 4021-4023. DOI: 10.1021/Ja00037A001  0.642
1991 Hopkins PB, Millard JT, Woo J, Weidner MF, Kirchner JJ, Sigurdsson ST, Raucher S. Sequence preferences of DNA interstrand cross-linking agents: Importance of minimal DNA structural reorganization in the cross-linking reactions of mechlorethamine, cisplatin and mitomycin C Tetrahedron. 47: 2475-2489. DOI: 10.1016/S0040-4020(01)81782-8  0.64
1990 Weidner MF, Sigurdsson ST, Hopkins PB. Sequence preferences of DNA interstrand cross-linking agents: dG-to-dG cross-linking at 5'-CG by structurally simplified analogues of mitomycin C. Biochemistry. 29: 9225-33. PMID 2125476 DOI: 10.1021/Bi00491A017  0.635
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