| Year |
Citation |
Score |
| 2023 |
Chen K, Zhang C, Lin S, Yan X, Cai H, Yi C, Ma L, Chu X, Liu Y, Zhu Y, Han S, Zhao Q, Wu B. Tail engagement of arrestin at the glucagon receptor. Nature. PMID 37558880 DOI: 10.1038/s41586-023-06420-x |
0.637 |
|
| 2023 |
Li Y, Zhou Q, Dai A, Zhao F, Chang R, Ying T, Wu B, Yang D, Wang MW, Cong Z. Structural analysis of the dual agonism at GLP-1R and GCGR. Proceedings of the National Academy of Sciences of the United States of America. 120: e2303696120. PMID 37549266 DOI: 10.1073/pnas.2303696120 |
0.504 |
|
| 2023 |
Wang X, Wang M, Xu T, Feng Y, Shao Q, Han S, Chu X, Xu Y, Lin S, Zhao Q, Wu B. Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers. Cell Research. PMID 37286794 DOI: 10.1038/s41422-023-00830-2 |
0.554 |
|
| 2023 |
Li B, Han S, Wang M, Yu Y, Ma L, Chu X, Tan Q, Zhao Q, Wu B. Structural insights into signal transduction of the purinergic receptors P2Y1R and P2Y12R. Protein & Cell. 14: 382-386. PMID 37155313 DOI: 10.1093/procel/pwac025 |
0.527 |
|
| 2022 |
Zhao W, Zhang W, Wang M, Lu M, Chen S, Tang T, Schnapp G, Wagner H, Brennauer A, Yi C, Chu X, Han S, Wu B, Zhao Q. Ligand recognition and activation of neuromedin U receptor 2. Nature Communications. 13: 7955. PMID 36575163 DOI: 10.1038/s41467-022-34814-4 |
0.586 |
|
| 2022 |
Lu M, Zhao W, Han S, Lin X, Xu T, Tan Q, Wang M, Yi C, Chu X, Yang W, Zhu Y, Wu B, Zhao Q. Activation of the human chemokine receptor CX3CR1 regulated by cholesterol. Science Advances. 8: eabn8048. PMID 35767622 DOI: 10.1126/sciadv.abn8048 |
0.613 |
|
| 2022 |
Zhao W, Han S, Qiu N, Feng W, Lu M, Zhang W, Wang M, Zhou Q, Chen S, Xu W, Du J, Chu X, Yi C, Dai A, Hu L, ... ... Wu B, et al. Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Research. PMID 35739238 DOI: 10.1038/s41422-022-00679-x |
0.596 |
|
| 2022 |
Tang T, Tan Q, Han S, Diemar A, Löbner K, Wang H, Schüß C, Behr V, Mörl K, Wang M, Chu X, Yi C, Keller M, Kofoed J, Reedtz-Runge S, ... ... Wu B, et al. Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors. Science Advances. 8: eabm1232. PMID 35507650 DOI: 10.1126/sciadv.abm1232 |
0.566 |
|
| 2022 |
Qu X, Qiu N, Wang M, Zhang B, Du J, Zhong Z, Xu W, Chu X, Ma L, Yi C, Han S, Shui W, Zhao Q, Wu B. Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Nature. PMID 35418679 DOI: 10.1038/s41586-022-04580-w |
0.584 |
|
| 2022 |
Zhu Y, Lin X, Zong X, Han S, Wang M, Su Y, Ma L, Chu X, Yi C, Zhao Q, Wu B. Structural basis of FPR2 in recognition of Aβ and neuroprotection by humanin. Nature Communications. 13: 1775. PMID 35365641 DOI: 10.1038/s41467-022-29361-x |
0.492 |
|
| 2021 |
Zhang X, He C, Wang M, Zhou Q, Yang D, Zhu Y, Feng W, Zhang H, Dai A, Chu X, Wang J, Yang Z, Jiang Y, Sensfuss U, Tan Q, ... ... Wu B, et al. Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nature Chemical Biology. PMID 34556863 DOI: 10.1038/s41589-021-00866-8 |
0.635 |
|
| 2021 |
Liu Q, Yang D, Zhuang Y, Croll TI, Cai X, Dai A, He X, Duan J, Yin W, Ye C, Zhou F, Wu B, Zhao Q, Xu HE, Wang MW, et al. Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor. Nature Chemical Biology. PMID 34556862 DOI: 10.1038/s41589-021-00841-3 |
0.521 |
|
| 2021 |
Zhang H, Chen K, Tan Q, Shao Q, Han S, Zhang C, Yi C, Chu X, Zhu Y, Xu Y, Zhao Q, Wu B. Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nature Communications. 12: 4151. PMID 34230484 DOI: 10.1038/s41467-021-24438-5 |
0.683 |
|
| 2021 |
Zhang H, Chen K, Tan Q, Shao Q, Han S, Zhang C, Yi C, Chu X, Zhu Y, Xu Y, Zhao Q, Wu B. Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5. Nature Communications. 12: 4151. PMID 34230484 DOI: 10.1038/s41467-021-24438-5 |
0.683 |
|
| 2021 |
Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, ... ... Wu B, et al. Structures of G-bound metabotropic glutamate receptors mGlu2 and mGlu4. Nature. PMID 34135510 DOI: 10.1038/s41586-021-03495-2 |
0.666 |
|
| 2021 |
Lin S, Han S, Cai X, Tan Q, Zhou K, Wang D, Wang X, Du J, Yi C, Chu X, Dai A, Zhou Y, Chen Y, Zhou Y, Liu H, ... ... Wu B, et al. Structures of G-bound metabotropic glutamate receptors mGlu2 and mGlu4. Nature. PMID 34135510 DOI: 10.1038/s41586-021-03495-2 |
0.666 |
|
| 2021 |
Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, ... ... Wu B, et al. Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature. PMID 34135509 DOI: 10.1038/s41586-021-03641-w |
0.652 |
|
| 2021 |
Du J, Wang D, Fan H, Xu C, Tai L, Lin S, Han S, Tan Q, Wang X, Xu T, Zhang H, Chu X, Yi C, Liu P, Wang X, ... ... Wu B, et al. Structures of human mGlu2 and mGlu7 homo- and heterodimers. Nature. PMID 34135509 DOI: 10.1038/s41586-021-03641-w |
0.652 |
|
| 2021 |
Tang T, Hartig C, Chen Q, Zhao W, Kaiser A, Zhang X, Zhang H, Qu H, Yi C, Ma L, Han S, Zhao Q, Beck-Sickinger AG, Wu B. Structural basis for ligand recognition of the neuropeptide Y Y receptor. Nature Communications. 12: 737. PMID 33531491 DOI: 10.1038/s41467-021-21030-9 |
0.617 |
|
| 2020 |
Ge YJ, Liao QW, Xu YC, Zhao Q, Wu BL, Ye RD. Anti-inflammatory signaling through G protein-coupled receptors. Acta Pharmacologica Sinica. PMID 33060777 DOI: 10.1038/s41401-020-00523-1 |
0.461 |
|
| 2020 |
Li X, Xie L, Qu X, Zhao B, Fu W, Wu B, Wu J. GPR91, a critical signaling mechanism in modulating pathophysiologic processes in chronic illnesses. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32812686 DOI: 10.1096/Fj.202001037R |
0.39 |
|
| 2020 |
Lo Giudice C, Zhang H, Wu B, Alsteens D. Mechanochemical activation of class-B G-protein coupled receptor upon peptide-ligand binding. Nano Letters. PMID 32578992 DOI: 10.1021/acs.nanolett.0c02333 |
0.493 |
|
| 2020 |
Chang R, Zhang X, Qiao A, Dai A, Belousoff MJ, Tan Q, Shao L, Zhong L, Lin G, Liang YL, Ma L, Han S, Yang D, Danev R, Wang MW, ... ... Wu B, et al. Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide. The Journal of Biological Chemistry. PMID 32371397 DOI: 10.1074/Jbc.Ra120.013793 |
0.489 |
|
| 2020 |
Qiao A, Han S, Li X, Li Z, Zhao P, Dai A, Chang R, Tai L, Tan Q, Chu X, Ma L, Thorsen TS, Reedtz-Runge S, Yang D, Wang MW, ... ... Wu B, et al. Structural basis of G and G recognition by the human glucagon receptor. Science (New York, N.Y.). 367: 1346-1352. PMID 32193322 DOI: 10.1126/Science.Aaz5346 |
0.56 |
|
| 2020 |
Chen T, Xiong M, Zong X, Ge Y, Zhang H, Wang M, Won Han G, Yi C, Ma L, Ye RD, Xu Y, Zhao Q, Wu B. Structural basis of ligand binding modes at the human formyl peptide receptor 2. Nature Communications. 11: 1208. PMID 32139677 DOI: 10.1038/S41467-020-15009-1 |
0.643 |
|
| 2020 |
Jacobson KA, Delicado EG, Gachet C, Kennedy C, von Kügelgen I, Li B, Miras-Portugal MT, Novak I, Schöneberg T, Perez-Sen R, Thor D, Wu B, Yang Z, Müller CE. Update of P2Y Receptor Pharmacology: IUPHAR Review:"27". British Journal of Pharmacology. PMID 32037507 DOI: 10.1111/Bph.15005 |
0.482 |
|
| 2019 |
Zhao S, Wu B, Stevens RC. Advancing Chemokine GPCR Structure Based Drug Discovery. Structure (London, England : 1993). 27: 405-408. PMID 30840872 DOI: 10.1016/J.Str.2019.02.004 |
0.646 |
|
| 2019 |
Chen S, Lu M, Liu D, Yang L, Yi C, Ma L, Zhang H, Liu Q, Frimurer TM, Wang MW, Schwartz TW, Stevens RC, Wu B, Wüthrich K, Zhao Q. Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography. Nature Communications. 10: 638. PMID 30733446 DOI: 10.1038/S41467-019-08568-5 |
0.729 |
|
| 2018 |
Fan H, Chen S, Yuan X, Han S, Zhang H, Xia W, Xu Y, Zhao Q, Wu B. Structural basis for ligand recognition of the human thromboxane A receptor. Nature Chemical Biology. PMID 30510189 DOI: 10.1038/S41589-018-0170-9 |
0.668 |
|
| 2018 |
Peng P, Chen H, Zhu Y, Wang ZL, Li J, Luo R, Wang J, Chen L, Yang LM, Jiang H, Xie X, Wu B, Zheng YT, Liu H. Structure-Based Design of 1-Heteroaryl-1,3-Propanediamine Derivatives as a Novel Series of CC-chemokine Receptor 5 (CCR5) Antagonists. Journal of Medicinal Chemistry. PMID 30234300 DOI: 10.1021/Acs.Jmedchem.8B01077 |
0.406 |
|
| 2018 |
Zhu Y, Zhao YL, Li J, Liu H, Zhao Q, Wu BL, Yang ZL. Molecular binding mode of PF-232798, a clinical anti-HIV candidate, at chemokine receptor CCR5. Acta Pharmacologica Sinica. PMID 29941870 DOI: 10.1038/S41401-018-0054-2 |
0.556 |
|
| 2018 |
Cao C, Tan Q, Xu C, He L, Yang L, Zhou Y, Zhou Y, Qiao A, Lu M, Yi C, Han GW, Wang X, Li X, Yang H, Rao Z, ... ... Wu B, et al. Structural basis for signal recognition and transduction by platelet-activating-factor receptor. Nature Structural & Molecular Biology. PMID 29808000 DOI: 10.1038/S41594-018-0068-Y |
0.705 |
|
| 2018 |
Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, ... ... Wu B, et al. Structural basis of ligand binding modes at the neuropeptide Y Y receptor. Nature. PMID 29670288 DOI: 10.1038/S41586-018-0046-X |
0.734 |
|
| 2018 |
Cao C, Zhang H, Yang Z, Wu B. Peptide recognition, signaling and modulation of class B G protein-coupled receptors. Current Opinion in Structural Biology. 51: 53-60. PMID 29567494 DOI: 10.1016/J.Sbi.2018.03.008 |
0.583 |
|
| 2018 |
Zhang H, Qiao A, Yang L, Van Eps N, Frederiksen KS, Yang D, Dai A, Cai X, Zhang H, Yi C, Cao C, He L, Yang H, Lau J, Ernst OP, ... ... Wu B, et al. Structure of the glucagon receptor in complex with a glucagon analogue. Nature. 553: 106-110. PMID 29300013 DOI: 10.1038/Nature25153 |
0.754 |
|
| 2017 |
de Graaf C, Song G, Cao C, Zhao Q, Wang MW, Wu B, Stevens RC. Extending the Structural View of Class B GPCRs. Trends in Biochemical Sciences. PMID 29132948 DOI: 10.1016/J.Tibs.2017.10.003 |
0.732 |
|
| 2017 |
Zheng Y, Han GW, Abagyan R, Wu B, Stevens RC, Cherezov V, Kufareva I, Handel TM. Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV. Immunity. 46: 1005-1017.e5. PMID 28636951 DOI: 10.1016/J.Immuni.2017.05.002 |
0.586 |
|
| 2017 |
Yen HY, Hopper JTS, Liko I, Allison TM, Zhu Y, Wang D, Stegmann M, Mohammed S, Wu B, Robinson CV. Ligand binding to a G protein-coupled receptor captured in a mass spectrometer. Science Advances. 3: e1701016. PMID 28630934 DOI: 10.1126/Sciadv.1701016 |
0.467 |
|
| 2017 |
Zhang H, Qiao A, Yang D, Yang L, Dai A, de Graaf C, Reedtz-Runge S, Dharmarajan V, Zhang H, Han GW, Grant TD, Sierra RG, Weierstall U, Nelson G, Liu W, ... ... Wu B, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. PMID 28514451 DOI: 10.1038/Nature22363 |
0.778 |
|
| 2017 |
Song G, Yang D, Wang Y, de Graaf C, Zhou Q, Jiang S, Liu K, Cai X, Dai A, Lin G, Liu D, Wu F, Wu Y, Zhao S, Ye L, ... ... Wu B, et al. Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators. Nature. PMID 28514449 DOI: 10.1038/Nature22378 |
0.746 |
|
| 2016 |
Hua T, Vemuri K, Pu M, Qu L, Han GW, Wu Y, Zhao S, Shui W, Li S, Korde A, Laprairie RB, Stahl EL, Ho JH, Zvonok N, Zhou H, ... ... Wu B, et al. Crystal Structure of the Human Cannabinoid Receptor CB1. Cell. 167: 750-762.e14. PMID 27768894 DOI: 10.1016/J.Cell.2016.10.004 |
0.764 |
|
| 2016 |
Lu M, Wu B. Structural studies of G protein-coupled receptors. Iubmb Life. PMID 27766738 DOI: 10.1002/Iub.1578 |
0.576 |
|
| 2015 |
Li D, Lei C, Zhang S, Zhang S, Liu M, Wu B. Blockade of high mobility group box-1 signaling via the receptor for advanced glycation end-products ameliorates inflammatory damage after acute intracerebral hemorrhage. Neuroscience Letters. PMID 26483322 DOI: 10.1016/j.neulet.2015.10.035 |
0.323 |
|
| 2015 |
LoPiccolo J, Kim SJ, Shi Y, Wu B, Wu H, Chait BT, Singer RH, Sali A, Brenowitz M, Bresnick AR, Backer JM. Assembly and Molecular Architecture of the Phosphoinositide 3-Kinase p85α Homodimer. The Journal of Biological Chemistry. PMID 26475863 DOI: 10.1074/Jbc.M115.689604 |
0.348 |
|
| 2015 |
Zhang D, Zhao Q, Wu B. Structural Studies of G Protein-Coupled Receptors. Molecules and Cells. PMID 26467290 DOI: 10.14348/molcells.2015.0263 |
0.581 |
|
| 2015 |
Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, et al. Conformational states of the full-length glucagon receptor. Nature Communications. 6: 7859. PMID 26227798 DOI: 10.1038/Ncomms8859 |
0.784 |
|
| 2015 |
Li C, Yeh FL, Cheung AY, Duan Q, Kita D, Liu MC, Maman J, Luu EJ, Wu BW, Gates L, Jalal M, Kwong A, Carpenter H, Wu HM. Glycosylphosphatidylinositol-anchored proteins as chaperones and co-receptors for FERONIA receptor kinase signaling in Arabidopsis. Elife. 4. PMID 26052747 DOI: 10.7554/Elife.06587 |
0.335 |
|
| 2015 |
Fenalti G, Abola EE, Wang C, Wu B, Cherezov V. Fluorescence Recovery After Photobleaching in Lipidic Cubic Phase (LCP-FRAP): A Precrystallization Assay for Membrane Proteins. Methods in Enzymology. 557: 417-37. PMID 25950976 DOI: 10.1016/Bs.Mie.2014.12.008 |
0.476 |
|
| 2015 |
Jacobson KA, Paoletta S, Katritch V, Wu B, Gao ZG, Zhao Q, Stevens RC, Kiselev E. Nucleotides Acting at P2Y Receptors: Connecting Structure and Function. Molecular Pharmacology. 88: 220-30. PMID 25837834 DOI: 10.1124/Mol.114.095711 |
0.791 |
|
| 2015 |
Zhang D, Gao ZG, Zhang K, Kiselev E, Crane S, Wang J, Paoletta S, Yi C, Ma L, Zhang W, Han GW, Liu H, Cherezov V, Katritch V, Jiang H, ... ... Wu B, et al. Two disparate ligand-binding sites in the human P2Y1 receptor. Nature. 520: 317-21. PMID 25822790 DOI: 10.1038/Nature14287 |
0.784 |
|
| 2014 |
Zhang J, Zhang K, Gao ZG, Paoletta S, Zhang D, Han GW, Li T, Ma L, Zhang W, Müller CE, Yang H, Jiang H, Cherezov V, Katritch V, Jacobson KA, ... ... Wu B, et al. Agonist-bound structure of the human P2Y12 receptor. Nature. 509: 119-22. PMID 24784220 DOI: 10.1038/Nature13288 |
0.797 |
|
| 2014 |
Zhang K, Zhang J, Gao ZG, Zhang D, Zhu L, Han GW, Moss SM, Paoletta S, Kiselev E, Lu W, Fenalti G, Zhang W, Müller CE, Yang H, Jiang H, ... ... Wu B, et al. Structure of the human P2Y12 receptor in complex with an antithrombotic drug. Nature. 509: 115-8. PMID 24670650 DOI: 10.1038/Nature13083 |
0.801 |
|
| 2013 |
Tan Q, Zhu Y, Li J, Chen Z, Han GW, Kufareva I, Li T, Ma L, Fenalti G, Li J, Zhang W, Xie X, Yang H, Jiang H, Cherezov V, ... ... Wu B, et al. Structure of the CCR5 chemokine receptor-HIV entry inhibitor maraviroc complex. Science (New York, N.Y.). 341: 1387-90. PMID 24030490 DOI: 10.1126/Science.1241475 |
0.669 |
|
| 2013 |
Zhu L, Zhao Q, Wu B. Structure-based studies of chemokine receptors. Current Opinion in Structural Biology. 23: 539-46. PMID 23706951 DOI: 10.1016/J.Sbi.2013.05.003 |
0.674 |
|
| 2013 |
Kufareva I, Stephens B, Gilliland CT, Wu B, Fenalti G, Hamel D, Stevens RC, Abagyan R, Handel TM. A novel approach to quantify G-protein-coupled receptor dimerization equilibrium using bioluminescence resonance energy transfer. Methods in Molecular Biology (Clifton, N.J.). 1013: 93-127. PMID 23625495 DOI: 10.1007/978-1-62703-426-5_7 |
0.612 |
|
| 2012 |
Zhao Q, Wu BL. Ice breaking in GPCR structural biology Acta Pharmacologica Sinica. 33: 324-334. PMID 22286917 DOI: 10.1038/Aps.2011.187 |
0.635 |
|
| 2010 |
Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC. Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science (New York, N.Y.). 330: 1066-71. PMID 20929726 DOI: 10.1126/Science.1194396 |
0.78 |
|
| 2007 |
Wu B, Liu Y, Zhao Q, Liao S, Zhang J, Bartlam M, Chen W, Rao Z. Crystal structure of RS21-C6, involved in nucleoside triphosphate pyrophosphohydrolysis. Journal of Molecular Biology. 367: 1405-12. PMID 17320107 DOI: 10.1016/J.Jmb.2007.01.057 |
0.468 |
|
| 2007 |
Zhao Q, Qin L, Jiang F, Wu B, Yue W, Xu F, Rong Z, Yuan H, Xie X, Gao Y, Bai C, Bartlam M, Pei X, Rao Z. Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation. The Journal of Biological Chemistry. 282: 647-56. PMID 17082182 DOI: 10.1074/jbc.M604029200 |
0.375 |
|
| 2004 |
Wu B, Li P, Liu Y, Lou Z, Ding Y, Shu C, Ye S, Bartlam M, Shen B, Rao Z. 3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex. Proceedings of the National Academy of Sciences of the United States of America. 101: 8348-53. PMID 15159550 DOI: 10.1073/pnas.0305969101 |
0.405 |
|
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