| Year |
Citation |
Score |
| 2023 |
Hippman RS, Snead AM, Petros ZA, Korkmaz-Vaisys MA, Patel S, Sotelo D, Dobria A, Salkovski M, Nguyen TTA, Linares R, Cologna SM, Gowrishankar S, Aldrich LN. Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons. Acs Chemical Neuroscience. PMID 38069806 DOI: 10.1021/acschemneuro.3c00573 |
0.38 |
|
| 2021 |
Salkovski M, Pavlinov I, Gao Q, Aldrich LN. Development of a High-Throughput, Compound-Multiplexed Fluorescence Polarization Assay to Identify ATG5-ATG16L1 Protein-Protein Interaction Inhibitors. Slas Discovery : Advancing Life Sciences R & D. 24725552211000679. PMID 33783243 DOI: 10.1177/24725552211000679 |
0.343 |
|
| 2020 |
Pavlinov I, Salkovski M, Aldrich LN. Selective autophagy inhibition through disruption of the PIK3C3-containing complex I Autophagy. 16: 1547-1549. PMID 32619130 DOI: 10.1080/15548627.2020.1786268 |
0.373 |
|
| 2020 |
Hippman RS, Pavlinov I, Gao Q, Mavlyanova MK, Gerlach EM, Aldrich L. Multiple chemical features impact biological performance diversity of a highly active natural product-inspired library. Chembiochem : a European Journal of Chemical Biology. PMID 32558167 DOI: 10.1002/Cbic.202000356 |
0.36 |
|
| 2020 |
Mathew B, Chennakesavalu M, Sharma M, Torres LA, Stelman CR, Tran S, Patel R, Burg N, Salkovski M, Kadzielawa K, Seiler F, Aldrich LN, Roth S. Autophagy and post-ischemic conditioning in retinal ischemia. Autophagy. 1-21. PMID 32452260 DOI: 10.1080/15548627.2020.1767371 |
0.324 |
|
| 2020 |
Pavlinov I, Salkovski M, Aldrich LN. Beclin 1-ATG14L Protein-Protein Interaction Inhibitor Selectively Inhibits Autophagy through Disruption of VPS34 Complex I. Journal of the American Chemical Society. 142: 8174-8182. PMID 32320221 DOI: 10.1021/Jacs.9B12705 |
0.412 |
|
| 2019 |
Aldrich LN. Lipids lead the way. Nature Chemical Biology. 15: 653-654. PMID 31222191 DOI: 10.1038/S41589-019-0309-3 |
0.382 |
|
| 2019 |
Gerlach EM, Korkmaz MA, Pavlinov I, Gao Q, Aldrich LN. Systematic diversity-oriented synthesis of reduced flavones from γ-pyrones to probe biological performance diversity. Acs Chemical Biology. PMID 31184855 DOI: 10.1021/Acschembio.9B00294 |
0.414 |
|
| 2018 |
Pavlinov I, Gerlach EM, Aldrich LN. Next generation diversity-oriented synthesis: a paradigm shift from chemical diversity to biological diversity. Organic & Biomolecular Chemistry. PMID 30328455 DOI: 10.1039/C8Ob02327A |
0.394 |
|
| 2018 |
Young AN, Herrera D, Huntsman AC, Korkmaz MA, Lantvit DD, Mazumder S, Kolli S, Coss CC, King S, Wang H, Swanson SM, Kinghorn AD, Zhang X, Phelps MA, Aldrich LN, et al. Phyllanthusmin derivatives induce apoptosis and reduce tumor burden in high grade serous ovarian cancer by late-stage autophagy inhibition. Molecular Cancer Therapeutics. PMID 30018048 DOI: 10.1158/1535-7163.Mct-17-1195 |
0.405 |
|
| 2018 |
Helgren TR, Xu LL, Sotelo D, Mehta YR, Korkmaz MA, Pavlinov I, Aldrich L. Microwave-assisted, asymmetric synthesis of 3-amino-2,3-dihydrobenzofuran flavonoid derivatives from chalcones. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29446184 DOI: 10.1002/Chem.201705984 |
0.729 |
|
| 2018 |
Young AN, Herrera D, Huntsman A, Lantvit DD, Korkmaz MA, Aldrich LN, Kinghorn AD, Fuchs JR, Burdette JE. Abstract 2672: Phyllanthusmins induce apoptosis and reduce tumor burden in high grade serous ovarian cancer by late-stage autophagy inhibition Cancer Research. 78: 2672-2672. DOI: 10.1158/1538-7445.Am2018-2672 |
0.384 |
|
| 2015 |
Kuo SY, Castoreno AB, Aldrich LN, Lassen KG, Goel G, Dan?ík V, Kuballa P, Latorre I, Conway KL, Sarkar S, Maetzel D, Jaenisch R, Clemons PA, Schreiber SL, Shamji AF, et al. Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics. Proceedings of the National Academy of Sciences of the United States of America. PMID 26195741 DOI: 10.1073/Pnas.1512289112 |
0.43 |
|
| 2015 |
Aldrich LN, Kuo SY, Castoreno AB, Goel G, Kuballa P, Rees MG, Seashore-Ludlow BA, Cheah JH, Latorre IJ, Schreiber SL, Shamji AF, Xavier RJ. Discovery of a Small-Molecule Probe for V-ATPase Function. Journal of the American Chemical Society. 137: 5563-8. PMID 25860544 DOI: 10.1021/Jacs.5B02150 |
0.446 |
|
| 2013 |
Aldrich LN, Berry CB, Bates BS, Konkol LC, So M, Lindsley CW. Towards the Total Synthesis of Marineosin A: Construction of the Macrocyclic Pyrrole and an Advanced, Functionalized Spiroaminal Model. European Journal of Organic Chemistry. 2013. PMID 24415906 DOI: 10.1002/Ejoc.201300643 |
0.58 |
|
| 2013 |
Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ. Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules. Acs Chemical Biology. 8: 2724-33. PMID 24168452 DOI: 10.1021/Cb400352D |
0.394 |
|
| 2013 |
Panarese JD, Konkol LC, Berry CB, Bates BS, Aldrich LN, Lindsley CW. Spiroaminal Model Systems of the Marineosins with Final Step Pyrrole Incorporation. Tetrahedron Letters. 54: 2231-2234. PMID 23606772 DOI: 10.1016/J.Tetlet.2013.02.059 |
0.545 |
|
| 2010 |
Aldrich LN, Stoops SL, Crews BC, Marnett LJ, Lindsley CW. Total synthesis and biological evaluation of tambjamine K and a library of unnatural analogs. Bioorganic & Medicinal Chemistry Letters. 20: 5207-11. PMID 20655217 DOI: 10.1016/J.Bmcl.2010.06.154 |
0.718 |
|
| 2010 |
Aldrich LN, Dawson ES, Lindsley CW. Evaluation of the biosynthetic proposal for the synthesis of marineosins A and B. Organic Letters. 12: 1048-51. PMID 20141121 DOI: 10.1021/Ol100034P |
0.562 |
|
| 2009 |
Aldrich LN, Lebois EP, Lewis LM, Nalywajko NT, Niswender CM, Weaver CD, Conn PJ, Lindsley CW. MAOS ls for the general synthesis and lead optimization of 3,6-disubstituted-[1,2,4]triazolo[4,3-b]pyridazines. Tetrahedron Letters. 50: 212-215. PMID 22090663 DOI: 10.1016/J.Tetlet.2008.10.127 |
0.694 |
|
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