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Clay C.C. Wang, Ph.D. - Publications

Affiliations: 
2003- Chemistry / Pharmacology University of Southern California, Los Angeles, CA, United States 
Area:
Natural Product Biosynthesis
Website:
https://pharmacyschool.usc.edu/faculty/clay-c-c-wang-phd/
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83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lan L, Liu J, Amith A, Appelman C, Wu X, Li K, Roy A, Gowthaman R, Karanicolas J, Somoza A, Wang C, Oakley B, Guzman RD, Neufeld K, Xu L. Abstract 3059: Identification and validation of an Aspergillusnidulanssecondary metabolite derivative as an inhibitor of the Musashi1-RNA interaction Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3059  0.754
2018 Lin TS, Chen B, Chiang YM, Wang C. Discovery and elucidation of the biosynthesis of aspernidgulenes, novel polyenes from Aspergillus nidulans, using serial promoter replacement. Chembiochem : a European Journal of Chemical Biology. PMID 30302871 DOI: 10.1002/Cbic.201800486  0.769
2018 Wu R, Murali R, Kabe Y, French SW, Chiang YM, Liu S, Sher L, Wang CC, Louie S, Tsukamoto H. Baicalein targets GTPase-mediated autophagy to eliminate liver tumor initiating stem cell-like cells resistant to mTORC1 inhibition. Hepatology (Baltimore, Md.). PMID 29729190 DOI: 10.1002/Hep.30071  0.524
2017 Singh NK, Blachowicz A, Romsdahl J, Wang C, Torok T, Venkateswaran K. Draft Genome Sequences of Several Fungal Strains Selected for Exposure to Microgravity at the International Space Station. Genome Announcements. 5. PMID 28408692 DOI: 10.1128/Genomea.01602-16  0.771
2017 Sung CT, Chang SL, Entwistle R, Ahn G, Lin TS, Petrova V, Yeh HH, Praseuth MB, Chiang YM, Oakley BR, Wang CC. Overexpression of a three-gene conidial pigment biosynthetic pathway in Aspergillus nidulans reveals the first NRPS known to acetylate tryptophan. Fungal Genetics and Biology : Fg & B. PMID 28108400 DOI: 10.1016/J.Fgb.2017.01.006  0.788
2016 van Dijk JW, Guo CJ, Wang CC. Engineering Fungal Nonribosomal Peptide Synthetase-like Enzymes by Heterologous Expression and Domain Swapping. Organic Letters. 18: 6236-6239. PMID 27978657 DOI: 10.1021/Acs.Orglett.6B02821  0.546
2016 Knox BP, Blachowicz A, Palmer JM, Romsdahl J, Huttenlocher A, Wang CC, Keller NP, Venkateswaran K. Characterization of Aspergillus fumigatus Isolates from Air and Surfaces of the International Space Station. Msphere. 1. PMID 27830189 DOI: 10.1128/mSphere.00227-16  0.774
2016 Oakley CE, Ahuja M, Sun WW, Entwistle R, Akashi T, Yaegashi J, Guo CJ, Cerqueira GC, Wortman JR, Wang CC, Chiang YM, Oakley BR. Discovery of McrA, a master regulator of Aspergillus secondary metabolism. Molecular Microbiology. PMID 27775185 DOI: 10.1111/Mmi.13562  0.799
2016 van Dijk JW, Wang CC. Heterologous Expression of Fungal Secondary Metabolite Pathways in the Aspergillus nidulans Host System. Methods in Enzymology. 575: 127-42. PMID 27417927 DOI: 10.1016/Bs.Mie.2016.02.021  0.472
2016 Singh NK, Blachowicz A, Checinska A, Wang C, Venkateswaran K. Draft Genome Sequences of Two Aspergillus fumigatus Strains, Isolated from the International Space Station. Genome Announcements. 4. PMID 27417828 DOI: 10.1128/Genomea.00553-16  0.747
2016 Yeh HH, Ahuja M, Chiang YM, Oakley CE, Moore S, Yoon O, Hajovsky H, Bok JW, Keller NP, Wang CC, Oakley BR. Resistance gene-guided genome mining: Serial promoter exchanges in Aspergillus nidulans reveal the biosynthetic pathway for fellutamide B, a proteasome inhibitor. Acs Chemical Biology. PMID 27294372 DOI: 10.1021/Acschembio.6B00213  0.629
2016 Lin TS, Chiang YM, Wang CC. Biosynthetic Pathway of the Reduced Polyketide Product Citreoviridin in Aspergillus terreus var. aureus Revealed by Heterologous Expression in Aspergillus nidulans. Organic Letters. PMID 26954888 DOI: 10.1021/Acs.Orglett.6B00299  0.784
2016 Sun WW, Guo CJ, Wang CC. Characterization of the Product of a Nonribosomal Peptide Synthetase-like (NRPS-like) Gene Using the Doxycycline Dependent Tet-ON System in Aspergillus terreus. Fungal Genetics and Biology : Fg & B. PMID 26851300 DOI: 10.1016/J.Fgb.2016.01.014  0.768
2016 Barkal LJ, Theberge AB, Guo CJ, Spraker J, Rappert L, Berthier J, Brakke KA, Wang CC, Beebe DJ, Keller NP, Berthier E. Microbial metabolomics in open microscale platforms. Nature Communications. 7: 10610. PMID 26842393 DOI: 10.1038/Ncomms10610  0.566
2015 Chiang YM, Ahuja M, Oakley CE, Entwistle R, Asokan A, Zutz C, Wang CC, Oakley BR. Development of Genetic Dereplication Strains in Aspergillus nidulans Results in the Discovery of Aspercryptin. Angewandte Chemie (International Ed. in English). PMID 26563584 DOI: 10.1002/Anie.201507097  0.648
2015 Paranjape SR, Riley AP, Somoza AD, Oakley CE, Wang CC, Prisinzano TE, Oakley BR, Gamblin TC. Azaphilones inhibit tau aggregation and dissolve tau aggregates in vitro. Acs Chemical Neuroscience. 6: 751-60. PMID 25822288 DOI: 10.1021/Acschemneuro.5B00013  0.765
2015 Gao YQ, Guo CJ, Zhang Q, Zhou WM, Wang CC, Gao JM. Asperaculanes A and B, two sesquiterpenoids from the fungus Aspergillus aculeatus. Molecules (Basel, Switzerland). 20: 325-34. PMID 25547729 DOI: 10.3390/Molecules20010325  0.521
2014 Guo CJ, Wang CC. Recent advances in genome mining of secondary metabolites in Aspergillus terreus. Frontiers in Microbiology. 5: 717. PMID 25566227 DOI: 10.3389/Fmicb.2014.00717  0.608
2014 Guo CJ, Sun WW, Bruno KS, Wang CC. Molecular genetic characterization of terreic acid pathway in Aspergillus terreus. Organic Letters. 16: 5250-3. PMID 25265334 DOI: 10.1021/Ol502242A  0.717
2014 Ishikawa N, Tanaka H, Koyama F, Noguchi H, Wang CC, Hotta K, Watanabe K. Non-heme dioxygenase catalyzes atypical oxidations of 6,7-bicyclic systems to form the 6,6-quinolone core of viridicatin-type fungal alkaloids. Angewandte Chemie (International Ed. in English). 53: 12880-4. PMID 25251934 DOI: 10.1002/Anie.201407920  0.505
2014 Liu T, Sanchez JF, Chiang YM, Oakley BR, Wang CC. Rational domain swaps reveal insights about chain length control by ketosynthase domains in fungal nonreducing polyketide synthases. Organic Letters. 16: 1676-9. PMID 24593241 DOI: 10.1021/Ol5003384  0.695
2014 Paranjape SR, Chiang YM, Sanchez JF, Entwistle R, Wang CC, Oakley BR, Gamblin TC. Inhibition of Tau aggregation by three Aspergillus nidulans secondary metabolites: 2,ω-dihydroxyemodin, asperthecin, and asperbenzaldehyde. Planta Medica. 80: 77-85. PMID 24414310 DOI: 10.1055/S-0033-1360180  0.689
2014 Yaegashi J, Oakley BR, Wang CC. Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans. Journal of Industrial Microbiology & Biotechnology. 41: 433-42. PMID 24342965 DOI: 10.1007/S10295-013-1386-Z  0.801
2013 Wiemann P, Guo CJ, Palmer JM, Sekonyela R, Wang CC, Keller NP. Prototype of an intertwined secondary-metabolite supercluster. Proceedings of the National Academy of Sciences of the United States of America. 110: 17065-70. PMID 24082142 DOI: 10.1073/Pnas.1313258110  0.634
2013 Bok JW, Soukup AA, Chadwick E, Chiang YM, Wang CC, Keller NP. VeA and MvlA repression of the cryptic orsellinic acid gene cluster in Aspergillus nidulans involves histone 3 acetylation. Molecular Microbiology. 89: 963-74. PMID 23841751 DOI: 10.1111/Mmi.12326  0.623
2013 Guo CJ, Knox BP, Sanchez JF, Chiang YM, Bruno KS, Wang CC. Application of an efficient gene targeting system linking secondary metabolites to their biosynthetic genes in Aspergillus terreus. Organic Letters. 15: 3562-5. PMID 23841722 DOI: 10.1021/Ol401384V  0.771
2013 Yaegashi J, Praseuth MB, Tyan SW, Sanchez JF, Entwistle R, Chiang YM, Oakley BR, Wang CC. Molecular genetic characterization of the biosynthesis cluster of a prenylated isoindolinone alkaloid aspernidine A in Aspergillus nidulans. Organic Letters. 15: 2862-5. PMID 23706169 DOI: 10.1021/Ol401187B  0.796
2013 Chiang YM, Oakley CE, Ahuja M, Entwistle R, Schultz A, Chang SL, Sung CT, Wang CC, Oakley BR. An efficient system for heterologous expression of secondary metabolite genes in Aspergillus nidulans. Journal of the American Chemical Society. 135: 7720-31. PMID 23621425 DOI: 10.1021/Ja401945A  0.643
2013 Berthier E, Lim FY, Deng Q, Guo CJ, Kontoyiannis DP, Wang CC, Rindy J, Beebe DJ, Huttenlocher A, Keller NP. Low-volume toolbox for the discovery of immunosuppressive fungal secondary metabolites. Plos Pathogens. 9: e1003289. PMID 23592999 DOI: 10.1371/Journal.Ppat.1003289  0.589
2013 Guo CJ, Yeh HH, Chiang YM, Sanchez JF, Chang SL, Bruno KS, Wang CC. Biosynthetic pathway for the epipolythiodioxopiperazine acetylaranotin in Aspergillus terreus revealed by genome-based deletion analysis. Journal of the American Chemical Society. 135: 7205-13. PMID 23586797 DOI: 10.1021/Ja3123653  0.794
2013 Chang SL, Chiang YM, Yeh HH, Wu TK, Wang CC. Reconstitution of the early steps of gliotoxin biosynthesis in Aspergillus nidulans reveals the role of the monooxygenase GliC. Bioorganic & Medicinal Chemistry Letters. 23: 2155-7. PMID 23434416 DOI: 10.1016/J.Bmcl.2013.01.099  0.622
2013 Yeh HH, Chang SL, Chiang YM, Bruno KS, Oakley BR, Wu TK, Wang CC. Engineering fungal nonreducing polyketide synthase by heterologous expression and domain swapping. Organic Letters. 15: 756-9. PMID 23368695 DOI: 10.1021/Ol303328T  0.545
2013 Yin WB, Reinke AW, Szilágyi M, Emri T, Chiang YM, Keating AE, Pócsi I, Wang CC, Keller NP. bZIP transcription factors affecting secondary metabolism, sexual development and stress responses in Aspergillus nidulans. Microbiology (Reading, England). 159: 77-88. PMID 23154967 DOI: 10.1099/Mic.0.063370-0  0.574
2012 Sanchez JF, Entwistle R, Corcoran D, Oakley BR, Wang CC. Identification and molecular genetic analysis of the cichorine gene cluster in Aspergillus nidulans. Medchemcomm. 3. PMID 24244835 DOI: 10.1039/C2Md20055D  0.653
2012 Guo CJ, Knox BP, Chiang YM, Lo HC, Sanchez JF, Lee KH, Oakley BR, Bruno KS, Wang CC. Molecular genetic characterization of a cluster in A. terreus for biosynthesis of the meroterpenoid terretonin. Organic Letters. 14: 5684-7. PMID 23116177 DOI: 10.1021/Ol302682Z  0.812
2012 Lim FY, Sanchez JF, Wang CC, Keller NP. Toward awakening cryptic secondary metabolite gene clusters in filamentous fungi. Methods in Enzymology. 517: 303-24. PMID 23084945 DOI: 10.1016/B978-0-12-404634-4.00015-2  0.658
2012 Sanchez JF, Wang CC. The chemical identification and analysis of Aspergillus nidulans secondary metabolites. Methods in Molecular Biology (Clifton, N.J.). 944: 97-109. PMID 23065610 DOI: 10.1007/978-1-62703-122-6_6  0.662
2012 Soukup AA, Chiang YM, Bok JW, Reyes-Dominguez Y, Oakley BR, Wang CC, Strauss J, Keller NP. Overexpression of the Aspergillus nidulans histone 4 acetyltransferase EsaA increases activation of secondary metabolite production. Molecular Microbiology. 86: 314-30. PMID 22882998 DOI: 10.1111/J.1365-2958.2012.08195.X  0.613
2012 Yeh HH, Chiang YM, Entwistle R, Ahuja M, Lee KH, Bruno KS, Wu TK, Oakley BR, Wang CC. Molecular genetic analysis reveals that a nonribosomal peptide synthetase-like (NRPS-like) gene in Aspergillus nidulans is responsible for microperfuranone biosynthesis. Applied Microbiology and Biotechnology. 96: 739-48. PMID 22627757 DOI: 10.1007/S00253-012-4098-9  0.655
2012 Ahuja M, Chiang YM, Chang SL, Praseuth MB, Entwistle R, Sanchez JF, Lo HC, Yeh HH, Oakley BR, Wang CC. Illuminating the diversity of aromatic polyketide synthases in Aspergillus nidulans. Journal of the American Chemical Society. 134: 8212-21. PMID 22510154 DOI: 10.1021/Ja3016395  0.793
2012 Lo HC, Entwistle R, Guo CJ, Ahuja M, Szewczyk E, Hung JH, Chiang YM, Oakley BR, Wang CC. Two separate gene clusters encode the biosynthetic pathway for the meroterpenoids austinol and dehydroaustinol in Aspergillus nidulans. Journal of the American Chemical Society. 134: 4709-20. PMID 22329759 DOI: 10.1021/Ja209809T  0.796
2012 Somoza AD, Lee KH, Chiang YM, Oakley BR, Wang CC. Reengineering an azaphilone biosynthesis pathway in Aspergillus nidulans to create lipoxygenase inhibitors. Organic Letters. 14: 972-5. PMID 22296232 DOI: 10.1021/Ol203094K  0.793
2012 Yin WB, Amaike S, Wohlbach DJ, Gasch AP, Chiang YM, Wang CC, Bok JW, Rohlfs M, Keller NP. An Aspergillus nidulans bZIP response pathway hardwired for defensive secondary metabolism operates through aflR. Molecular Microbiology. 83: 1024-34. PMID 22283524 DOI: 10.1111/J.1365-2958.2012.07986.X  0.613
2012 Sanchez JF, Somoza AD, Keller NP, Wang CC. Advances in Aspergillus secondary metabolite research in the post-genomic era. Natural Product Reports. 29: 351-71. PMID 22228366 DOI: 10.1039/C2Np00084A  0.783
2012 Yang MD, Chiang YM, Higashiyama R, Asahina K, Mann DA, Mann J, Wang CC, Tsukamoto H. Rosmarinic acid and baicalin epigenetically derepress peroxisomal proliferator-activated receptor γ in hepatic stellate cells for their antifibrotic effect. Hepatology (Baltimore, Md.). 55: 1271-81. PMID 22095555 DOI: 10.1002/Hep.24792  0.576
2011 Liu T, Chiang YM, Somoza AD, Oakley BR, Wang CC. Engineering of an "unnatural" natural product by swapping polyketide synthase domains in Aspergillus nidulans. Journal of the American Chemical Society. 133: 13314-6. PMID 21815681 DOI: 10.1021/Ja205780G  0.774
2011 Li AY, Lin HH, Kuo CY, Shih HM, Wang CC, Yen Y, Ann DK. High-mobility group A2 protein modulates hTERT transcription to promote tumorigenesis. Molecular and Cellular Biology. 31: 2605-17. PMID 21536653 DOI: 10.1128/Mcb.05447-11  0.572
2011 Giles SS, Soukup AA, Lauer C, Shaaban M, Lin A, Oakley BR, Wang CC, Keller NP. Cryptic Aspergillus nidulans antimicrobials. Applied and Environmental Microbiology. 77: 3669-75. PMID 21478304 DOI: 10.1128/Aem.02000-10  0.45
2011 Sanchez JF, Entwistle R, Hung JH, Yaegashi J, Jain S, Chiang YM, Wang CC, Oakley BR. Genome-based deletion analysis reveals the prenyl xanthone biosynthesis pathway in Aspergillus nidulans. Journal of the American Chemical Society. 133: 4010-7. PMID 21351751 DOI: 10.1021/Ja1096682  0.812
2011 Chiang YM, Meyer KM, Praseuth M, Baker SE, Bruno KS, Wang CC. Characterization of a polyketide synthase in Aspergillus niger whose product is a precursor for both dihydroxynaphthalene (DHN) melanin and naphtho-γ-pyrone. Fungal Genetics and Biology : Fg & B. 48: 430-7. PMID 21176790 DOI: 10.1016/J.Fgb.2010.12.001  0.641
2011 Chiang YM, Chang SL, Oakley BR, Wang CC. Recent advances in awakening silent biosynthetic gene clusters and linking orphan clusters to natural products in microorganisms. Current Opinion in Chemical Biology. 15: 137-43. PMID 21111669 DOI: 10.1016/J.Cbpa.2010.10.011  0.642
2010 Palmer JM, Mallaredy S, Perry DW, Sanchez JF, Theisen JM, Szewczyk E, Oakley BR, Wang CC, Keller NP, Mirabito PM. Telomere position effect is regulated by heterochromatin-associated proteins and NkuA in Aspergillus nidulans. Microbiology (Reading, England). 156: 3522-31. PMID 20724388 DOI: 10.1099/Mic.0.039255-0  0.609
2010 Chiang YM, Oakley BR, Keller NP, Wang CC. Unraveling polyketide synthesis in members of the genus Aspergillus. Applied Microbiology and Biotechnology. 86: 1719-36. PMID 20361326 DOI: 10.1007/S00253-010-2525-3  0.593
2010 Cheng YF, Ou HY, Tsang LL, Yu CY, Huang TL, Chen TY, Concejero A, Wang CC, Wang SH, Lin TS, Liu YW, Yang CH, Yong CC, Chiu KW, Jawan B, et al. Vascular stents in the management of portal venous complications in living donor liver transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10: 1276-83. PMID 20353467 DOI: 10.1111/j.1600-6143.2010.03076.x  0.685
2010 Sanchez JF, Chiang YM, Szewczyk E, Davidson AD, Ahuja M, Elizabeth Oakley C, Woo Bok J, Keller N, Oakley BR, Wang CC. Molecular genetic analysis of the orsellinic acid/F9775 gene cluster of Aspergillus nidulans. Molecular Biosystems. 6: 587-93. PMID 20174687 DOI: 10.1039/B904541D  0.722
2010 Wang CC, Chiang YM, Praseuth MB, Kuo PL, Liang HL, Hsu YL. Asperfuranone from Aspergillus nidulans inhibits proliferation of human non-small cell lung cancer A549 cells via blocking cell cycle progression and inducing apoptosis. Basic & Clinical Pharmacology & Toxicology. 107: 583-9. PMID 20148857 DOI: 10.1111/J.1742-7843.2010.00545.X  0.548
2010 Chiang YM, Szewczyk E, Davidson AD, Entwistle R, Keller NP, Wang CC, Oakley BR. Characterization of the Aspergillus nidulans monodictyphenone gene cluster. Applied and Environmental Microbiology. 76: 2067-74. PMID 20139316 DOI: 10.1128/Aem.02187-09  0.645
2009 Chiang YM, Lee KH, Sanchez JF, Keller NP, Wang CC. Unlocking fungal cryptic natural products. Natural Product Communications. 4: 1505-10. PMID 19967983 DOI: 10.1177/1934578X0900401113  0.729
2009 Watanabe K, Hotta K, Praseuth AP, Searcey M, Wang CC, Oguri H, Oikawa H. Rationally engineered total biosynthesis of a synthetic analogue of a natural quinomycin depsipeptide in Escherichia coli. Chembiochem : a European Journal of Chemical Biology. 10: 1965-8. PMID 19588480 DOI: 10.1002/Cbic.200900260  0.78
2009 Li AY, Boo LM, Wang SY, Lin HH, Wang CC, Yen Y, Chen BP, Chen DJ, Ann DK. Suppression of nonhomologous end joining repair by overexpression of HMGA2. Cancer Research. 69: 5699-706. PMID 19549901 DOI: 10.1158/0008-5472.Can-08-4833  0.55
2009 Watanabe K, Hotta K, Nakaya M, Praseuth AP, Wang CC, Inada D, Takahashi K, Fukushi E, Oguri H, Oikawa H. Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent antibiotic unnatural natural product. Journal of the American Chemical Society. 131: 9347-53. PMID 19514719 DOI: 10.1021/Ja902261A  0.812
2009 Bok JW, Chiang YM, Szewczyk E, Reyes-Dominguez Y, Davidson AD, Sanchez JF, Lo HC, Watanabe K, Strauss J, Oakley BR, Wang CC, Keller NP. Chromatin-level regulation of biosynthetic gene clusters. Nature Chemical Biology. 5: 462-4. PMID 19448638 DOI: 10.1038/Nchembio.177  0.788
2009 Chiang YM, Szewczyk E, Davidson AD, Keller N, Oakley BR, Wang CC. A gene cluster containing two fungal polyketide synthases encodes the biosynthetic pathway for a polyketide, asperfuranone, in Aspergillus nidulans. Journal of the American Chemical Society. 131: 2965-70. PMID 19199437 DOI: 10.1021/Ja8088185  0.673
2008 Praseuth AP, Wang CC, Watanabe K, Hotta K, Oguri H, Oikawa H. Complete sequence of biosynthetic gene cluster responsible for producing triostin A and evaluation of quinomycin-type antibiotics from Streptomyces triostinicus. Biotechnology Progress. 24: 1226-31. PMID 19194935 DOI: 10.1002/Btpr.34  0.805
2008 Szewczyk E, Chiang YM, Oakley CE, Davidson AD, Wang CC, Oakley BR. Identification and characterization of the asperthecin gene cluster of Aspergillus nidulans. Applied and Environmental Microbiology. 74: 7607-12. PMID 18978088 DOI: 10.1128/Aem.01743-08  0.658
2008 Wang CC, Chiang YM, Kuo PL, Chang JK, Hsu YL. Norsolorinic acid inhibits proliferation of T24 human bladder cancer cells by arresting the cell cycle at the G0/G1 phase and inducing a Fas/membrane-bound Fas ligand-mediated apoptotic pathway. Clinical and Experimental Pharmacology & Physiology. 35: 1301-8. PMID 18671724 DOI: 10.1111/J.1440-1681.2008.05007.X  0.542
2008 Chiang YM, Szewczyk E, Nayak T, Davidson AD, Sanchez JF, Lo HC, Ho WY, Simityan H, Kuo E, Praseuth A, Watanabe K, Oakley BR, Wang CC. Molecular genetic mining of the Aspergillus secondary metabolome: discovery of the emericellamide biosynthetic pathway. Chemistry & Biology. 15: 527-32. PMID 18559263 DOI: 10.1016/J.Chembiol.2008.05.010  0.807
2008 Wang CC, Chiang YM, Kuo PL, Chang JK, Hsu YL. Norsolorinic acid from Aspergillus nidulans inhibits the proliferation of human breast adenocarcinoma MCF-7 cells via Fas-mediated pathway. Basic & Clinical Pharmacology & Toxicology. 102: 491-7. PMID 18346044 DOI: 10.1111/J.1742-7843.2008.00237.X  0.548
2008 Sanchez JF, Chiang YM, Wang CC. Diversity of polyketide synthases found in the Aspergillus and Streptomyces genomes. Molecular Pharmaceutics. 5: 226-33. PMID 18338869 DOI: 10.1021/Mp700139T  0.717
2008 Praseuth AP, Praseuth MB, Oguri H, Oikawa H, Watanabe K, Wang CC. Improved production of triostin A in engineered Escherichia coli with furnished quinoxaline chromophore by design of experiments in small-scale culture. Biotechnology Progress. 24: 134-9. PMID 18173279 DOI: 10.1021/Bp070298Y  0.793
2008 Wang CC, Chiang YM, Sung SC, Hsu YL, Chang JK, Kuo PL. Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells. Cancer Letters. 259: 82-98. PMID 18023967 DOI: 10.1016/J.Canlet.2007.10.005  0.55
2007 Hsu CF, Phillips JW, Trauger JW, Farkas ME, Belitsky JM, Heckel A, Olenyuk BZ, Puckett JW, Wang CC, Dervan PB. Completion of a Programmable DNA-Binding Small Molecule Library. Tetrahedron. 63: 6146-6151. PMID 18596841 DOI: 10.1016/J.Tet.2007.03.041  0.746
2007 Marques MA, Citron DM, Wang CC. Development of Tyrocidine A analogues with improved antibacterial activity. Bioorganic & Medicinal Chemistry. 15: 6667-77. PMID 17728134 DOI: 10.1016/j.bmc.2007.08.007  0.576
2007 Ma SM, Zhan J, Watanabe K, Xie X, Zhang W, Wang CC, Tang Y. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. Journal of the American Chemical Society. 129: 10642-3. PMID 17696354 DOI: 10.1021/Ja074865P  0.516
2007 Zhang W, Watanabe K, Wang CC, Tang Y. Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway. The Journal of Biological Chemistry. 282: 25717-25. PMID 17631493 DOI: 10.1074/Jbc.M703437200  0.637
2007 Watanabe K, Praseuth AP, Wang CC. A comprehensive and engaging overview of the type III family of polyketide synthases. Current Opinion in Chemical Biology. 11: 279-86. PMID 17482864 DOI: 10.1016/J.Cbpa.2006.11.041  0.799
2006 Zhang W, Watanabe K, Wang CC, Tang Y. Heterologous biosynthesis of amidated polyketides with novel cyclization regioselectivity from oxytetracycline polyketide synthase. Journal of Natural Products. 69: 1633-6. PMID 17125237 DOI: 10.1021/Np060290I  0.631
2006 Xie X, Watanabe K, Wojcicki WA, Wang CC, Tang Y. Biosynthesis of lovastatin analogs with a broadly specific acyltransferase. Chemistry & Biology. 13: 1161-9. PMID 17113998 DOI: 10.1016/J.Chembiol.2006.09.008  0.65
2006 Watanabe K, Hotta K, Praseuth AP, Koketsu K, Migita A, Boddy CN, Wang CC, Oguri H, Oikawa H. Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli. Nature Chemical Biology. 2: 423-8. PMID 16799553 DOI: 10.1038/Nchembio803  0.79
2003 Pfeifer BA, Wang CC, Walsh CT, Khosla C. Biosynthesis of Yersiniabactin, a complex polyketide-nonribosomal peptide, using Escherichia coli as a heterologous host. Applied and Environmental Microbiology. 69: 6698-702. PMID 14602630 DOI: 10.1128/Aem.69.11.6698-6702.2003  0.687
2003 Watanabe K, Wang CC, Boddy CN, Cane DE, Khosla C. Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases. The Journal of Biological Chemistry. 278: 42020-6. PMID 12923197 DOI: 10.1074/Jbc.M305339200  0.761
2001 Wang CC, Dervan PB. Sequence-specific trapping of topoisomerase I by DNA binding polyamide-camptothecin conjugates. Journal of the American Chemical Society. 123: 8657-61. PMID 11535069 DOI: 10.1021/Ja010392P  0.507
2001 Wang CC, Ellervik U, Dervan PB. Expanding the recognition of the minor groove of DNA by incorporation of beta-alanine in hairpin polyamides. Bioorganic & Medicinal Chemistry. 9: 653-7. PMID 11310600 DOI: 10.1016/S0968-0896(00)00282-0  0.5
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