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Benjamin R. Taft, Ph.D. - Publications

Affiliations: 
2004-2008 University of California, Santa Barbara, Santa Barbara, CA, United States 
 2011- Chemistry Novartis Institute for BioMedical Research 
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Trost BM, Taft BR, Tracy JS, Stivala CE. Catalytic Asymmetric Synthesis of the Pentacyclic Core of (+)-Citrinadin A. Organic Letters. PMID 34114462 DOI: 10.1021/acs.orglett.1c01389  0.372
2019 Ramurthy S, Taft BR, Aversa RJ, Barsanti P, Burger MT, Lou Y, Nishiguchi G, Rico A, Setti L, Smith A, Subramanian S, Tamez VNA, Tanner HR, Wan L, Hu C, et al. Design and Discovery of N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide (LXH254)- A selective, efficacious and well-tolerated RAF inhibitor targeting RAS mutant cancers: The path to the clinic. Journal of Medicinal Chemistry. PMID 31059256 DOI: 10.1021/Acs.Jmedchem.9B00161  0.443
2017 Nishiguchi GA, Rico A, Tanner HR, Aversa RJ, Taft BR, Subramanian S, Setti L, Burger MT, Wan L, Tamez VNA, Smith A, Lou Y, Barsanti PA, Appleton BA, Mamo M, et al. Design and Discovery of N-(2-methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A potent, selective and efficacious RAF inhibitor targeting RAS mutant cancers. Journal of Medicinal Chemistry. PMID 28557458 DOI: 10.1021/Acs.Jmedchem.6B01862  0.447
2016 Trost BM, Masters JT, Taft BR, Lumb JP. Asymmetric synthesis of chiral β-alkynyl carbonyl and sulfonyl derivatives via sequential palladium and copper catalysis. Chemical Science. 7: 6217-6231. PMID 27746892 DOI: 10.1039/C6Sc01724J  0.707
2012 Lipshutz BH, Isley NA, Moser R, Ghorai S, Leuser H, Taft BR. Rhodium-Catalyzed Asymmetric 1,4-Additions, in Water at Room Temperature, with In-Flask Catalyst Recycling. Advanced Synthesis & Catalysis. 354: 3175-3179. PMID 24659941 DOI: 10.1002/Adsc.201200160  0.697
2012 Lipshutz BH, Taft BR, Abela AR, Ghorai S, Krasovskiy A, Duplais C. Catalysis in the Service of Green Chemistry: Nobel Prize-Winning Palladium-Catalysed Cross-Couplings, Run in Water at Room Temperature: Heck, Suzuki-Miyaura and Negishi reactions carried out in the absence of organic solvents, enabled by micellar catalysis. Platinum Metals Review. 56: 62-74. PMID 23555153 DOI: 10.1595/147106712X629761  0.752
2011 Trost BM, Taft BR, Masters JT, Lumb JP. A new strategy for the synthesis of chiral β-alkynyl esters via sequential palladium and copper catalysis. Journal of the American Chemical Society. 133: 8502-5. PMID 21557627 DOI: 10.1021/Ja203171X  0.697
2011 Lipshutz BH, Ghorai S, Leong WW, Taft BR, Krogstad DV. Manipulating micellar environments for enhancing transition metal-catalyzed cross-couplings in water at room temperature. The Journal of Organic Chemistry. 76: 5061-73. PMID 21539384 DOI: 10.1021/Jo200746Y  0.593
2011 Trost BM, Taft BR, Masters JT, Lumb J. ChemInform Abstract: A New Strategy for the Synthesis of Chiral β-Alkynyl Esters via Sequential Palladium and Copper Catalysis. Cheminform. 42: no-no. DOI: 10.1002/chin.201145019  0.671
2009 Gallagher BD, Taft BR, Lipshutz BH. Asymmetric conjugate reductions of coumarins. A new route to tolterodine and related coumarin derivatives. Organic Letters. 11: 5374-7. PMID 19877705 DOI: 10.1021/Ol9020404  0.498
2009 Taft BR, Swift EC, Lipshutz BH. A convenient preparation of di-p-chlorobenzyl azodicarboxylate (DCAD) for mitsunobu couplings Synthesis. 332-334. DOI: 10.1055/S-0028-1083274  0.515
2009 Nulwala H, Takizawa K, Odukale A, Khan A, Thibault RJ, Taft BR, Lipshutz BH, Hawker CJ. Synthesis and characterization of isomeric vinyl-1,2,3-triazole materials by azide - Alkyne click chemistry Macromolecules. 42: 6068-6074. DOI: 10.1021/Ma900892H  0.55
2008 Lipshutz BH, Nihan DM, Vinogradova E, Taft BR, Bosković ZV. Copper + nickel-in-charcoal (Cu-Ni/C): a bimetallic, heterogeneous catalyst for cross-couplings. Organic Letters. 10: 4279-82. PMID 18763793 DOI: 10.1021/Ol801676U  0.755
2008 Lipshutz BH, Taft BR. Heck couplings at room temperature in nanometer aqueous micelles. Organic Letters. 10: 1329-32. PMID 18335945 DOI: 10.1021/Ol702755G  0.502
2007 Lipshutz BH, Unger JB, Taft BR. Copper-in-charcoal (Cu/C) promoted diaryl ether formation. Organic Letters. 9: 1089-92. PMID 17305352 DOI: 10.1021/Ol0700409  0.715
2007 Lipshutz BH, Lee CT, Taft BR. A conjugate reduction pathway to chiral silanes using CuH Synthesis. 3257-3260. DOI: 10.1055/S-2007-983830  0.662
2007 Lipshutz B, Taft B. Cu/C Catalyst for Click Chemistry Synfacts. 2007: 0340-0340. DOI: 10.1055/s-2007-968222  0.304
2006 Lipshutz BH, Frieman BA, Lee CT, Lower A, Nihan DM, Taft BR. Microwave-assisted heterogeneous cross-coupling reactions catalyzed by nickel-in-charcoal (Ni/C). Chemistry, An Asian Journal. 1: 417-29. PMID 17441078 DOI: 10.1002/Asia.200600031  0.711
2006 Lipshutz BH, Taft BR. Heterogeneous copper-in-charcoal-catalyzed click chemistry. Angewandte Chemie (International Ed. in English). 45: 8235-8. PMID 17111447 DOI: 10.1002/Anie.200603726  0.545
2006 Lipshutz BH, Tanaka N, Taft BR, Lee CT. Chiral silanes via asymmetric hydrosilylation with catalytic CuH. Organic Letters. 8: 1963-6. PMID 16671757 DOI: 10.1021/Ol0529593  0.678
2006 Lipshutz BH, Butler T, Frieman BA, Kogan V, Lee CT, Lower A, Nihan DM, Taft BR, Tomaso AE. New technologies in catalysis using base metals Pure and Applied Chemistry. 78: 377-384. DOI: 10.1351/Pac200678020377  0.691
2005 Frieman BA, Taft BR, Lee CT, Butler T, Lipshutz BH. Nickel-in-charcoal (Ni/C): An efficient heterogeneous catalyst for the construction of C-C, C-N, and C-H bonds Synthesis. 2989-2993. DOI: 10.1055/S-2005-872145  0.785
2004 Lipshutz BH, Servesko JM, Taft BR. Asymmetric 1,4-hydrosilylations of alpha,beta-unsaturated esters. Journal of the American Chemical Society. 126: 8352-3. PMID 15237972 DOI: 10.1021/Ja049135L  0.692
2004 Ball DB, Wood M, Lindsley C, Mollard P, Buzard DJ, Vivian R, Mahoney M, Taft BR. Research, Teaching, and Professional Development at a Comprehensive University Journal of Chemical Education. 81: 1796. DOI: 10.1021/Ed081P1796  0.533
2004 Lipshutz BH, Servesko JM, Taft BR. Asymmetric 1,4-Hydrosilylations of α,β-Unsaturated Esters. Cheminform. 35. DOI: 10.1002/chin.200445024  0.678
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