Pankaj Kumar, PhD - Publications

Affiliations: 
2005-2010 Protein science and Engineering CSIR-Institute of Microbial Technology,Chandigarh 
 2011-2014 Biophysics and Biophysical Chemistry Johns Hopkins University, Baltimore, MD 
 2014-2018 Tuberculosis Research Center Johns Hopkins University School of Medicine, Baltimore, MD, United States 
 2018- Biochemistry Jamia Hamdard, New Delhi, India 
Area:
Crystallography, Ubiquitin biology, Drug Discovery, ß-lactams, Drug resistance, Molecular biophysics, Chemical biology, Mycobacterium tuberculosis, Non-Tubercular Mycobacteria, Biochemistry
Website:
http://pankajimtech.webs.com

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Krug S, Gupta M, Kumar P, Feller L, Ihms EA, Kang BG, Srikrishna G, Dawson TM, Dawson VL, Bishai WR. Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide. Nature Communications. 14: 8161. PMID 38071218 DOI: 10.1038/s41467-023-43937-1  0.644
2023 Wazahat R, Juneja P, Chauhan V, Zaidi R, Lamichhane G, Singh UB, Haider M, Kumar P. A strip-based assay for detection of CrfA enzyme activity to differentiate Mycobacterium tuberculosis and non-tuberculous mycobacteria. Journal of Microbiological Methods. 211: 106781. PMID 37437716 DOI: 10.1016/j.mimet.2023.106781  0.737
2022 Ahmad N, Dugad S, Chauhan V, Ahmed S, Sharma K, Kachhap S, Zaidi R, Bishai WR, Lamichhane G, Kumar P. Allosteric cooperation in ß-lactam binding to a non-classical transpeptidase. Elife. 11. PMID 35475970 DOI: 10.7554/eLife.73055  0.753
2022 Galanis C, Maggioncalda EC, Kumar P, Lamichhane G. Glby, Encoded by , Is Required for Growth of Mycobacteroides abscessus and Exhibits Mild β-Lactamase Activity. Journal of Bacteriology. e0004622. PMID 35380462 DOI: 10.1128/jb.00046-22  0.715
2019 Saxena R, Stanley CB, Kumar P, Cuneo MJ, Patil D, Jha J, Weiss KL, Chattoraj DK, Crooke E. A nucleotide-dependent oligomerization of the Escherichia coli replication initiator DnaA requires residue His136 for remodeling of the chromosomal origin. Nucleic Acids Research. PMID 31665475 DOI: 10.1093/Nar/Gkz939  0.304
2019 Kumar P, Kumar A, Parveen S, Murphy JR, Bishai W. Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy. Immunotherapy. PMID 31361167 DOI: 10.2217/Imt-2019-0060  0.708
2019 Cheung LS, Fu J, Kumar P, Kumar A, Urbanowski ME, Ihms EA, Parveen S, Bullen CK, Patrick GJ, Harrison R, Murphy JR, Pardoll DM, Bishai WR. Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718426 DOI: 10.1073/Pnas.1815087116  0.685
2017 Kumar P, Chauhan V, Silva JRA, Lameira J, d'Andrea F, Li S, Ginell SL, Freundlich JS, Alves CN, Bailey S, Cohen KA, Lamichhane G. Mycobacterium abscessus L,D-transpeptidases are susceptible to inactivation by carbapenems and cephalosporins but not penicillins. Antimicrobial Agents and Chemotherapy. PMID 28760902 DOI: 10.1128/Aac.00866-17  0.798
2017 Mattoo R, Lloyd EP, Kaushik A, Kumar P, Brunelle JL, Townsend CA, Lamichhane G. LdtMav2, a nonclassical transpeptidase and susceptibility of Mycobacterium avium to carbapenems. Future Microbiology. PMID 28555497 DOI: 10.2217/Fmb-2016-0208  0.758
2017 Bianchet MA, Pan YH, Basta LAB, Saavedra H, Lloyd EP, Kumar P, Mattoo R, Townsend CA, Lamichhane G. Structural insight into the inactivation of Mycobacterium tuberculosis non-classical transpeptidase LdtMt2 by biapenem and tebipenem. Bmc Biochemistry. 18: 8. PMID 28545389 DOI: 10.1186/S12858-017-0082-4  0.617
2017 Dey RJ, Dey B, Zheng Y, Cheung LS, Zhou J, Sayre D, Kumar P, Guo H, Lamichhane G, Sintim HO, Bishai WR. Inhibition of innate immune cytosolic surveillance by an M. tuberculosis phosphodiesterase. Nature Chemical Biology. 13: 210-217. PMID 28106876 DOI: 10.1038/Nchembio.2254  0.775
2017 Kumar P, Kaushik A, Bell D, Chauhan V, Xia F, Stevens RL, Lamichhane G. Mutation in an unannotated protein confers carbapenem resistance in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 28069655 DOI: 10.1128/Aac.02234-16  0.774
2016 Kumar P, Kaushik A, Lloyd EP, Li SG, Mattoo R, Ammerman NC, Bell DT, Perryman AL, Zandi TA, Ekins S, Ginell SL, Townsend CA, Freundlich JS, Lamichhane G. Non-classical transpeptidases yield insight into new antibacterials. Nature Chemical Biology. PMID 27820797 DOI: 10.1038/Nchembio.2237  0.776
2015 Ekins S, Madrid PB, Sarker M, Li SG, Mittal N, Kumar P, Wang X, Stratton TP, Zimmerman M, Talcott C, Bourbon P, Travers M, Yadav M, Freundlich JS. Combining Metabolite-Based Pharmacophores with Bayesian Machine Learning Models for Mycobacterium tuberculosis Drug Discovery. Plos One. 10: e0141076. PMID 26517557 DOI: 10.1371/Journal.Pone.0141076  0.613
2015 Kumar P, Magala P, Geiger-Schuller KR, Majumdar A, Tolman JR, Wolberger C. Role of a non-canonical surface of Rad6 in ubiquitin conjugating activity. Nucleic Acids Research. PMID 26286193 DOI: 10.1093/Nar/Gkv845  0.725
2015 Kumar P, Wolberger C. Structure of the yeast Bre1 RING domain. Proteins. 83: 1185-90. PMID 25864391 DOI: 10.1002/Prot.24812  0.545
2013 Singh M, Kumar P, Yadav S, Gautam R, Sharma N, Karthikeyan S. The crystal structure reveals the molecular mechanism of bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II (Rv1415) from Mycobacterium tuberculosis. Acta Crystallographica. Section D, Biological Crystallography. 69: 1633-44. PMID 23999287 DOI: 10.1107/S0907444913011402  0.346
2011 Kumar P, Singh M, Karthikeyan S. Crystal structure analysis of icosahedral lumazine synthase from Salmonella typhimurium, an antibacterial drug target. Acta Crystallographica. Section D, Biological Crystallography. 67: 131-9. PMID 21245535 DOI: 10.1107/S0907444910053370  0.31
2010 Kumar P, Singh M, Gautam R, Karthikeyan S. Potential anti-bacterial drug target: structural characterization of 3,4-dihydroxy-2-butanone-4-phosphate synthase from Salmonella typhimurium LT2. Proteins. 78: 3292-303. PMID 20806221 DOI: 10.1002/Prot.22837  0.305
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