| Year |
Citation |
Score |
| 2020 |
Fairfax BP, Taylor CA, Watson RA, Nassiri I, Danielli S, Fang H, Mahé EA, Cooper R, Woodcock V, Traill Z, Al-Mossawi MH, Knight JC, Klenerman P, Payne M, Middleton MR. Peripheral CD8 T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma. Nature Medicine. PMID 32042196 DOI: 10.1038/s41591-019-0734-6 |
0.52 |
|
| 2019 |
Al-Mossawi H, Yager N, Taylor CA, Lau E, Danielli S, de Wit J, Gilchrist J, Nassiri I, Mahe EA, Lee W, Rizvi L, Makino S, Cheeseman J, Neville M, Knight JC, ... ... Fairfax BP, et al. Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele. Nature Communications. 10: 4575. PMID 31594933 DOI: 10.1038/S41467-019-12393-1 |
0.66 |
|
| 2019 |
Fang H, De Wolf H, Knezevic B, Burnham KL, Osgood J, Sanniti A, Lledó Lara A, Kasela S, De Cesco S, Wegner JK, Handunnetthi L, McCann FE, Chen L, Sekine T, ... ... Fairfax BP, et al. A genetics-led approach defines the drug target landscape of 30 immune-related traits. Nature Genetics. PMID 31253980 DOI: 10.1038/S41588-019-0456-1 |
0.493 |
|
| 2019 |
Al-Mossawi H, Yager N, Taylor C, Danielli S, Gilchrist J, Nassiri I, Mahe E, Knight J, Fairfax BP, Bowness P. O32 Ankylosing spondylitis associated polymorphism of the IL7R controls expression surface and soluble IL7R-alpha during in inflammation Rheumatology. 58. DOI: 10.1093/RHEUMATOLOGY/KEZ105.031 |
0.482 |
|
| 2019 |
Fairfax B, Taylor C, Watson R, Nassiri I, Fang H, Mahe E, Cooper R, Danielli S, Woodcock V, Traill Z, Knight J, Payne M, Middleton M. Early peripheral T-cell responses predict oncological outcome to checkpoint immune blockade in metastatic melanoma Annals of Oncology. 30: v486-v487. DOI: 10.1093/annonc/mdz253.020 |
0.46 |
|
| 2018 |
Gilchrist JJ, Rautanen A, Fairfax BP, Mills TC, Naranbhai V, Trochet H, Pirinen M, Muthumbi E, Mwarumba S, Njuguna P, Mturi N, Msefula CL, Gondwe EN, MacLennan JM, Chapman SJ, et al. Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4. Nature Communications. 9: 1014. PMID 29523850 DOI: 10.1038/s41467-017-02398-z |
0.537 |
|
| 2017 |
Al-Mossawi MH, Chen L, Fang H, Ridley A, de Wit J, Yager N, Hammitzsch A, Pulyakhina I, Fairfax BP, Simone D, Yi Y, Bandyopadhyay S, Doig K, Gundle R, Kendrick B, et al. Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis. Nature Communications. 8: 1510. PMID 29142230 DOI: 10.1038/S41467-017-01771-2 |
0.501 |
|
| 2017 |
Kasela S, Kisand K, Tserel L, Kaleviste E, Remm A, Fischer K, Esko T, Westra HJ, Fairfax BP, Makino S, Knight JC, Franke L, Metspalu A, Peterson P, Milani L. Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells. Plos Genetics. 13: e1006643. PMID 28248954 DOI: 10.1371/Journal.Pgen.1006643 |
0.639 |
|
| 2016 |
Vince N, Li H, Ramsuran V, Naranbhai V, Duh FM, Fairfax BP, Saleh B, Knight JC, Anderson SK, Carrington M. HLA-C Level Is Regulated by a Polymorphic Oct1 Binding Site in the HLA-C Promoter Region. American Journal of Human Genetics. PMID 27817866 DOI: 10.1016/j.ajhg.2016.09.023 |
0.516 |
|
| 2015 |
Naranbhai V, Fletcher HA, Tanner R, O'Shea MK, McShane H, Fairfax BP, Knight JC, Hill AV. Distinct Transcriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes. Ebiomedicine. 2: 1619-1626. PMID 26870787 DOI: 10.1016/j.ebiom.2015.09.027 |
0.538 |
|
| 2015 |
Bentham J, Morris DL, Cunninghame Graham DS, Pinder CL, Tombleson P, Behrens TW, Martín J, Fairfax BP, Knight JC, Chen L, Replogle J, Syvänen AC, Rönnblom L, Graham RR, Wither JE, et al. Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus. Nature Genetics. PMID 26502338 DOI: 10.1038/Ng.3434 |
0.588 |
|
| 2015 |
Gilchrist JJ, Mills TC, Naranbhai V, Chapman SJ, Fairfax BP, Knight JC, Williams TN, Scott JA, MacLennan CA, Rautanen A, Hill AV. Genetic variants associated with non-typhoidal Salmonella bacteraemia in African children. Lancet (London, England). 385: S13. PMID 26312835 DOI: 10.1016/S0140-6736(15)60328-2 |
0.488 |
|
| 2015 |
Naranbhai V, Fairfax BP, Makino S, Humburg P, Wong D, Ng E, Hill AV, Knight JC. Genomic modulators of gene expression in human neutrophils. Nature Communications. 6: 7545. PMID 26151758 DOI: 10.1038/Ncomms8545 |
0.67 |
|
| 2015 |
Westra HJ, Arends D, Esko T, Peters MJ, Schurmann C, Schramm K, Kettunen J, Yaghootkar H, Fairfax BP, Andiappan AK, Li Y, Fu J, Karjalainen J, Platteel M, Visschedijk M, et al. Cell Specific eQTL Analysis without Sorting Cells. Plos Genetics. 11: e1005223. PMID 25955312 DOI: 10.1371/Journal.Pgen.1005223 |
0.644 |
|
| 2015 |
Naranbhai V, Fairfax BP, Makino S, Humburg P, Wong D, Ng E, Hill AVS, Knight JC. Genomic modulators of gene expression in human neutrophils Nature Communications. 6. DOI: 10.1038/ncomms8545 |
0.618 |
|
| 2015 |
Naranbhai V, Fletcher HA, Tanner R, O'Shea MK, McShane H, Fairfax BP, Knight JC, Hill AVS. Distinct Ttranscriptional and Anti-Mycobacterial Profiles of Peripheral Blood Monocytes Dependent on the Ratio of Monocytes: Lymphocytes Ebiomedicine. DOI: 10.1016/j.ebiom.2015.09.027 |
0.465 |
|
| 2014 |
Wong D, Lee W, Humburg P, Makino S, Lau E, Naranbhai V, Fairfax BP, Chan K, Plant K, Knight JC. Genomic mapping of the MHC transactivator CIITA using an integrated ChIP-seq and genetical genomics approach. Genome Biology. 15: 494. PMID 25366989 DOI: 10.1186/S13059-014-0494-Z |
0.667 |
|
| 2014 |
Fairfax BP, Knight JC. Genetics of gene expression in immunity to infection. Current Opinion in Immunology. 30: 63-71. PMID 25078545 DOI: 10.1016/j.coi.2014.07.001 |
0.547 |
|
| 2014 |
Fairfax BP, Humburg P, Makino S, Naranbhai V, Wong D, Lau E, Jostins L, Plant K, Andrews R, McGee C, Knight JC. Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression. Science (New York, N.Y.). 343: 1246949. PMID 24604202 DOI: 10.1126/Science.1246949 |
0.665 |
|
| 2014 |
Plant K, Fairfax BP, Makino S, Vandiedonck C, Radhakrishnan J, Knight JC. Fine mapping genetic determinants of the highly variably expressed MHC gene ZFP57. European Journal of Human Genetics : Ejhg. 22: 568-71. PMID 24193346 DOI: 10.1038/Ejhg.2013.244 |
0.655 |
|
| 2014 |
Simpson NH, Addis L, Brandler WM, Slonims V, Clark A, Watson J, Scerri TS, Hennessy ER, Bolton PF, Conti-Ramsden G, Fairfax BP, Knight JC, Stein J, Talcott JB, O'Hare A, et al. Increased prevalence of sex chromosome aneuploidies in specific language impairment and dyslexia. Developmental Medicine and Child Neurology. 56: 346-53. PMID 24117048 DOI: 10.1111/Dmcn.12294 |
0.444 |
|
| 2013 |
Westra HJ, Peters MJ, Esko T, Yaghootkar H, Schurmann C, Kettunen J, Christiansen MW, Fairfax BP, Schramm K, Powell JE, Zhernakova A, Zhernakova DV, Veldink JH, Van den Berg LH, Karjalainen J, et al. Systematic identification of trans eQTLs as putative drivers of known disease associations. Nature Genetics. 45: 1238-43. PMID 24013639 DOI: 10.1038/Ng.2756 |
0.658 |
|
| 2013 |
Bønnelykke K, Matheson MC, Pers TH, Granell R, Strachan DP, Alves AC, Linneberg A, Curtin JA, Warrington NM, Standl M, Kerkhof M, Jonsdottir I, Bukvic BK, Kaakinen M, Sleimann P, ... ... Fairfax BP, et al. Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization. Nature Genetics. 45: 902-6. PMID 23817571 DOI: 10.1038/Ng.2694 |
0.552 |
|
| 2013 |
Guo Y, Lanktree MB, Taylor KC, Hakonarson H, Lange LA, Keating BJ, Fairfax BP, Elbers CC, Barnard J, Farrall M, Padmanabhan S, Baumert J, Castillo BA, Gaunt TR, Gong Y, et al. Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals Human Molecular Genetics. 22: 184-201. PMID 23001569 DOI: 10.1093/Hmg/Dds396 |
0.493 |
|
| 2012 |
Fairfax BP, Makino S, Radhakrishnan J, Plant K, Leslie S, Dilthey A, Ellis P, Langford C, Vannberg FO, Knight JC. Genetics of gene expression in primary immune cells identifies cell type-specific master regulators and roles of HLA alleles. Nature Genetics. 44: 502-10. PMID 22446964 DOI: 10.1038/Ng.2205 |
0.677 |
|
| 2011 |
Vandiedonck C, Taylor MS, Lockstone HE, Plant K, Taylor JM, Durrant C, Broxholme J, Fairfax BP, Knight JC. Pervasive haplotypic variation in the spliceo-transcriptome of the human major histocompatibility complex. Genome Research. 21: 1042-54. PMID 21628452 DOI: 10.1101/gr.116681.110 |
0.593 |
|
| 2011 |
Fairfax BP, Davenport EE, Makino S, Hill AV, Vannberg FO, Knight JC. A common haplotype of the TNF receptor 2 gene modulates endotoxin tolerance. Journal of Immunology (Baltimore, Md. : 1950). 186: 3058-65. PMID 21282507 DOI: 10.4049/Jimmunol.1001791 |
0.615 |
|
| 2010 |
Wong SH, Gochhait S, Malhotra D, Pettersson FH, Teo YY, Khor CC, Rautanen A, Chapman SJ, Mills TC, Srivastava A, Rudko A, Freidin MB, Puzyrev VP, Ali S, Aggarwal S, ... ... Fairfax BP, et al. Leprosy and the adaptation of human toll-like receptor 1. Plos Pathogens. 6: e1000979. PMID 20617178 DOI: 10.1371/Journal.Ppat.1000979 |
0.567 |
|
| 2010 |
Fairfax BP, Vannberg FO, Radhakrishnan J, Hakonarson H, Keating BJ, Hill AV, Knight JC. An integrated expression phenotype mapping approach defines common variants in LEP, ALOX15 and CAPNS1 associated with induction of IL-6. Human Molecular Genetics. 19: 720-30. PMID 19942621 DOI: 10.1093/Hmg/Ddp530 |
0.547 |
|
| 2010 |
Vandiedonck C, Taylor M, Lockstone H, Plant K, Taylor J, Fairfax B, Durrant C, Broxholme J, Knight J. The First Transcriptional Map of the Human Major Histocompatibility Complex Reveals New Transcripts and Haplotype-specific Pattern of Expression Clinical Immunology. 135: S9. DOI: 10.1016/J.Clim.2010.03.035 |
0.493 |
|
| 2007 |
Kuramoto N, Wilkins ME, Fairfax BP, Revilla-Sanchez R, Terunuma M, Tamaki K, Iemata M, Warren N, Couve A, Calver A, Horvath Z, Freeman K, Carling D, Huang L, Gonzales C, et al. Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase. Neuron. 53: 233-47. PMID 17224405 DOI: 10.1016/J.Neuron.2006.12.015 |
0.691 |
|
| 2006 |
Morgan R, Fairfax B, Pandha HS. Calcium insensitivity of FA-6, a cell line derived from a pancreatic cancer associated with humoral hypercalcemia, is mediated by the significantly reduced expression of the Calcium Sensitive Receptor transduction component p38 MAPK. Molecular Cancer. 5: 51. PMID 17078869 DOI: 10.1186/1476-4598-5-51 |
0.372 |
|
| 2004 |
Thuault SJ, Brown JT, Sheardown SA, Jourdain S, Fairfax B, Spencer JP, Restituito S, Nation JH, Topps S, Medhurst AD, Randall AD, Couve A, Moss SJ, Collingridge GL, Pangalos MN, et al. The GABA(B2) subunit is critical for the trafficking and function of native GABA(B) receptors. Biochemical Pharmacology. 68: 1655-66. PMID 15451409 DOI: 10.1016/J.Bcp.2004.07.032 |
0.736 |
|
| 2004 |
Couve A, Calver AR, Fairfax B, Moss SJ, Pangalos MN. Unravelling the unusual signalling properties of the GABA(B) receptor. Biochemical Pharmacology. 68: 1527-36. PMID 15451395 DOI: 10.1016/j.bcp.2004.06.036 |
0.696 |
|
| 2004 |
Fairfax BP, Pitcher JA, Scott MG, Calver AR, Pangalos MN, Moss SJ, Couve A. Phosphorylation and chronic agonist treatment atypically modulate GABAB receptor cell surface stability. The Journal of Biological Chemistry. 279: 12565-73. PMID 14707142 DOI: 10.1074/jbc.M311389200 |
0.703 |
|
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