| Year |
Citation |
Score |
| 2022 |
Vermilyea SC, Christensen A, Meints J, Singh B, Martell-Martínez H, Karim MR, Lee MK. Loss of tau expression attenuates neurodegeneration associated with α-synucleinopathy. Translational Neurodegeneration. 11: 34. PMID 35773715 DOI: 10.1186/s40035-022-00309-x |
0.607 |
|
| 2020 |
Karim MR, Liao EE, Kim J, Meints J, Martinez HM, Pletnikova O, Troncoso JC, Lee MK. α-Synucleinopathy associated c-Abl activation causes p53-dependent autophagy impairment. Molecular Neurodegeneration. 15: 27. PMID 32299471 DOI: 10.1186/S13024-020-00364-W |
0.325 |
|
| 2019 |
Stanojlovic M, Pallais JP, Lee MK, Kotz CM. Pharmacological and chemogenetic orexin/hypocretin intervention ameliorates Hipp-dependent memory impairment in the A53T mice model of Parkinson's disease. Molecular Brain. 12: 87. PMID 31666100 DOI: 10.1186/S13041-019-0514-8 |
0.323 |
|
| 2019 |
Singh B, Covelo A, Martell-Martínez H, Nanclares C, Sherman MA, Okematti E, Meints J, Teravskis PJ, Gallardo C, Savonenko AV, Benneyworth MA, Lesné SE, Liao D, Araque A, Lee MK. Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy. Acta Neuropathologica. PMID 31168644 DOI: 10.1007/S00401-019-02032-W |
0.605 |
|
| 2018 |
Teravskis PJ, Covelo A, Miller EC, Singh B, Martell-Martínez HA, Benneyworth MA, Gallardo C, Oxnard BR, Araque A, Lee MK, Liao D. A53T mutant alpha-synuclein induces tau dependent postsynaptic impairment independent of neurodegenerative changes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30249789 DOI: 10.1523/Jneurosci.0344-18.2018 |
0.668 |
|
| 2018 |
Khan SS, LaCroix M, Boyle G, Sherman MA, Brown JL, Amar F, Aldaco J, Lee MK, Bloom GS, Lesné SE. Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons. Acta Neuropathologica. PMID 29995210 DOI: 10.1007/S00401-018-1886-Z |
0.392 |
|
| 2017 |
Ordonez DG, Lee MK, Feany MB. α-synuclein Induces Mitochondrial Dysfunction through Spectrin and the Actin Cytoskeleton. Neuron. PMID 29249285 DOI: 10.1016/J.Neuron.2017.11.036 |
0.481 |
|
| 2017 |
Colla E, Panattoni G, Ricci A, Rizzi C, Rota L, Carucci N, Valvano V, Gobbo F, Capsoni S, Lee MK, Cattaneo A. Toxic properties of microsome-associated alpha-synuclein species in mouse primary neurons. Neurobiology of Disease. 111: 36-47. PMID 29246724 DOI: 10.1016/J.Nbd.2017.12.004 |
0.345 |
|
| 2017 |
Salazar SV, Gallardo C, Kaufman AC, Herber CS, Haas LT, Robinson S, Manson JC, Lee MK, Strittmatter SM. Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28842420 DOI: 10.1523/Jneurosci.0722-17.2017 |
0.347 |
|
| 2017 |
Larson ME, Greimel SJ, Amar F, LaCroix M, Boyle G, Sherman MA, Schley H, Miel C, Schneider JA, Kayed R, Benfenati F, Lee MK, Bennett DA, Lesné SE. Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533388 DOI: 10.1073/Pnas.1704698114 |
0.387 |
|
| 2017 |
Jung BC, Lim YJ, Bae EJ, Lee JS, Choi MS, Lee MK, Lee HJ, Kim YS, Lee SJ. Amplification of distinct α-synuclein fibril conformers through protein misfolding cyclic amplification. Experimental & Molecular Medicine. 49: e314. PMID 28386127 DOI: 10.1038/Emm.2017.1 |
0.33 |
|
| 2015 |
Adare A, Afanasiev S, Aidala C, Ajitanand NN, Akiba Y, Akimoto R, Al-Bataineh H, Alexander J, Alfred M, Al-Ta'ani H, Andrews KR, Angerami A, Aoki K, Apadula N, Aphecetche L, ... ... Lee MK, et al. Measurements of Elliptic and Triangular Flow in High-Multiplicity 3He+Au Collisions at √(s(NN))=200 GeV. Physical Review Letters. 115: 142301. PMID 26551807 DOI: 10.1103/Physrevlett.115.142301 |
0.392 |
|
| 2013 |
Adare A, Afanasiev S, Aidala C, Ajitanand NN, Akiba Y, Akimoto R, Al-Bataineh H, Al-Ta'ani H, Alexander J, Angerami A, Aoki K, Apadula N, Aphecetche L, Aramaki Y, Armendariz R, ... ... Lee MK, et al. Medium modification of jet fragmentation in Au+Au collisions at √[s(NN)]=200 GeV measured in direct photon-hadron correlations. Physical Review Letters. 111: 032301. PMID 23909311 DOI: 10.1103/Physrevlett.111.032301 |
0.399 |
|
| 2012 |
Nguyen L, Wright S, Lee M, Ren Z, Sauer JM, Hoffman W, Zago W, Kinney GG, Bova MP. Quantifying amyloid beta (Aβ)-mediated changes in neuronal morphology in primary cultures: implications for phenotypic screening. Journal of Biomolecular Screening. 17: 835-42. PMID 22473881 DOI: 10.1177/1087057112441972 |
0.33 |
|
| 2012 |
Colla E, Coune P, Liu Y, Pletnikova O, Troncoso JC, Iwatsubo T, Schneider BL, Lee MK. Endoplasmic reticulum stress is important for the manifestations of α-synucleinopathy in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3306-20. PMID 22399753 DOI: 10.1523/Jneurosci.5367-11.2012 |
0.32 |
|
| 2012 |
Colla E, Jensen PH, Pletnikova O, Troncoso JC, Glabe C, Lee MK. Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 3301-5. PMID 22399752 DOI: 10.1523/Jneurosci.5368-11.2012 |
0.341 |
|
| 2012 |
Daher JP, Pletnikova O, Biskup S, Musso A, Gellhaar S, Galter D, Troncoso JC, Lee MK, Dawson TM, Dawson VL, Moore DJ. Neurodegenerative phenotypes in an A53T α-synuclein transgenic mouse model are independent of LRRK2. Human Molecular Genetics. 21: 2420-31. PMID 22357653 DOI: 10.1093/Hmg/Dds057 |
0.367 |
|
| 2012 |
Chen G, Xu Y, Lee M. Degeneration of cholingeric afferent in a transgenic mouse model of Alzheimer's disease: Lack of correlation with proximity to amyloid plaques Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2013.08.099 |
0.354 |
|
| 2011 |
Ramonet D, Daher JP, Lin BM, Stafa K, Kim J, Banerjee R, Westerlund M, Pletnikova O, Glauser L, Yang L, Liu Y, Swing DA, Beal MF, Troncoso JC, McCaffery JM, ... ... Lee MK, et al. Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2. Plos One. 6: e18568. PMID 21494637 DOI: 10.1371/Journal.Pone.0018568 |
0.355 |
|
| 2011 |
Thomas B, Mandir AS, West N, Liu Y, Andrabi SA, Stirling W, Dawson VL, Dawson TM, Lee MK. Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation. Plos One. 6: e16706. PMID 21304957 DOI: 10.1371/Journal.Pone.0016706 |
0.377 |
|
| 2011 |
Liu Y, Lee MK, James MM, Price DL, Borchelt DR, Troncoso JC, Oh ES. Passive (amyloid-β) immunotherapy attenuates monoaminergic axonal degeneration in the AβPPswe/PS1dE9 mice. Journal of Alzheimer's Disease : Jad. 23: 271-9. PMID 20966549 DOI: 10.3233/Jad-2010-101602 |
0.3 |
|
| 2010 |
Basi GS, Hemphill S, Brigham EF, Liao A, Aubele DL, Baker J, Barbour R, Bova M, Chen XH, Dappen MS, Eichenbaum T, Goldbach E, Hawkinson J, Lawler-Herbold R, Hu K, ... ... Lee M, et al. Amyloid precursor protein selective gamma-secretase inhibitors for treatment of Alzheimer's disease. Alzheimer's Research & Therapy. 2: 36. PMID 21190552 DOI: 10.1186/Alzrt60 |
0.312 |
|
| 2010 |
Smith WW, Liu Z, Liang Y, Masuda N, Swing DA, Jenkins NA, Copeland NG, Troncoso JC, Pletnikov M, Dawson TM, Martin LJ, Moran TH, Lee MK, Borchelt DR, Ross CA. Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model. Human Molecular Genetics. 19: 2087-98. PMID 20185556 DOI: 10.1093/Hmg/Ddq086 |
0.349 |
|
| 2010 |
Basi GS, Feinberg H, Oshidari F, Anderson J, Barbour R, Baker J, Comery TA, Diep L, Gill D, Johnson-Wood K, Goel A, Grantcharova K, Lee M, Li J, Partridge A, et al. Structural correlates of antibodies associated with acute reversal of amyloid beta-related behavioral deficits in a mouse model of Alzheimer disease. The Journal of Biological Chemistry. 285: 3417-27. PMID 19923222 DOI: 10.1074/Jbc.M109.045187 |
0.311 |
|
| 2009 |
Adare A, Afanasiev S, Aidala C, Ajitanand NN, Akiba Y, Al-Bataineh H, Alexander J, Aoki K, Aphecetche L, Armendariz R, Aronson SH, Asai J, Atomssa ET, Averbeck R, Awes TC, ... ... Lee MK, et al. Measurement of bottom versus charm as a function of transverse momentum with electron-hadron correlations in p + p collisions at square root of s = 200 GeV. Physical Review Letters. 103: 082002. PMID 19792719 DOI: 10.1103/Physrevlett.103.082002 |
0.386 |
|
| 2009 |
Yang Q, She H, Gearing M, Colla E, Lee M, Shacka JJ, Mao Z. Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy. Science (New York, N.Y.). 323: 124-7. PMID 19119233 DOI: 10.1126/Science.1166088 |
0.348 |
|
| 2008 |
Liu Y, Yoo MJ, Savonenko A, Stirling W, Price DL, Borchelt DR, Mamounas L, Lyons WE, Blue ME, Lee MK. Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13805-14. PMID 19091971 DOI: 10.1523/Jneurosci.4218-08.2008 |
0.354 |
|
| 2008 |
Adare A, Afanasiev S, Aidala C, Ajitanand NN, Akiba Y, Al-Bataineh H, Alexander J, Aoki K, Aphecetche L, Armendariz R, Aronson SH, Asai J, Atomssa ET, Averbeck R, Awes TC, ... ... Lee MK, et al. Onset of pi(0) suppression studied in Cu+Cu collisions at sqrt S NN=22.4, 62.4, and 200 GeV. Physical Review Letters. 101: 162301. PMID 18999660 DOI: 10.1103/Physrevlett.101.162301 |
0.379 |
|
| 2008 |
Wang J, Martin E, Gonzales V, Borchelt DR, Lee MK. Differential regulation of small heat shock proteins in transgenic mouse models of neurodegenerative diseases. Neurobiology of Aging. 29: 586-97. PMID 17316906 DOI: 10.1016/J.Neurobiolaging.2006.11.009 |
0.347 |
|
| 2007 |
McConlogue L, Buttini M, Anderson JP, Brigham EF, Chen KS, Freedman SB, Games D, Johnson-Wood K, Lee M, Zeller M, Liu W, Motter R, Sinha S. Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice. The Journal of Biological Chemistry. 282: 26326-34. PMID 17616527 DOI: 10.1074/Jbc.M611687200 |
0.351 |
|
| 2007 |
Miller RM, Kiser GL, Kaysser-Kranich T, Casaceli C, Colla E, Lee MK, Palaniappan C, Federoff HJ. Wild-type and mutant alpha-synuclein induce a multi-component gene expression profile consistent with shared pathophysiology in different transgenic mouse models of PD. Experimental Neurology. 204: 421-32. PMID 17254569 DOI: 10.1016/J.Expneurol.2006.12.005 |
0.353 |
|
| 2006 |
Riekse RG, Li G, Petrie EC, Leverenz JB, Vavrek D, Vuletic S, Albers JJ, Montine TJ, Lee VM, Lee M, Seubert P, Galasko D, Schellenberg GD, Hazzard WR, Peskind ER. Effect of statins on Alzheimer's disease biomarkers in cerebrospinal fluid. Journal of Alzheimer's Disease : Jad. 10: 399-406. PMID 17183151 DOI: 10.3233/Jad-2006-10408 |
0.324 |
|
| 2006 |
Anderson JP, Walker DE, Goldstein JM, de Laat R, Banducci K, Caccavello RJ, Barbour R, Huang J, Kling K, Lee M, Diep L, Keim PS, Shen X, Chataway T, Schlossmacher MG, et al. Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease. The Journal of Biological Chemistry. 281: 29739-52. PMID 16847063 DOI: 10.1074/Jbc.M600933200 |
0.326 |
|
| 2006 |
von Coelln R, Thomas B, Andrabi SA, Lim KL, Savitt JM, Saffary R, Stirling W, Bruno K, Hess EJ, Lee MK, Dawson VL, Dawson TM. Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3685-96. PMID 16597723 DOI: 10.1523/Jneurosci.0414-06.2006 |
0.324 |
|
| 2006 |
Martin LJ, Pan Y, Price AC, Sterling W, Copeland NG, Jenkins NA, Price DL, Lee MK. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 41-50. PMID 16399671 DOI: 10.1523/Jneurosci.4308-05.2006 |
0.363 |
|
| 2006 |
Unger EL, Eve DJ, Perez XA, Reichenbach DK, Xu Y, Lee MK, Andrews AM. Locomotor hyperactivity and alterations in dopamine neurotransmission are associated with overexpression of A53T mutant human alpha-synuclein in mice. Neurobiology of Disease. 21: 431-43. PMID 16230020 DOI: 10.1016/J.Nbd.2005.08.005 |
0.313 |
|
| 2005 |
Lee M, Bard F, Johnson-Wood K, Lee C, Hu K, Griffith SG, Black RS, Schenk D, Seubert P. Abeta42 immunization in Alzheimer's disease generates Abeta N-terminal antibodies. Annals of Neurology. 58: 430-5. PMID 16130106 DOI: 10.1002/Ana.20592 |
0.316 |
|
| 2005 |
Masliah E, Rockenstein E, Adame A, Alford M, Crews L, Hashimoto M, Seubert P, Lee M, Goldstein J, Chilcote T, Games D, Schenk D. Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease. Neuron. 46: 857-68. PMID 15953415 DOI: 10.1016/J.Neuron.2005.05.010 |
0.357 |
|
| 2005 |
Li W, Lee MK. Antiapoptotic property of human alpha-synuclein in neuronal cell lines is associated with the inhibition of caspase-3 but not caspase-9 activity. Journal of Neurochemistry. 93: 1542-50. PMID 15935070 DOI: 10.1111/J.1471-4159.2005.03146.X |
0.349 |
|
| 2005 |
Pletnikova O, West N, Lee MK, Rudow GL, Skolasky RL, Dawson TM, Marsh L, Troncoso JC. Abeta deposition is associated with enhanced cortical alpha-synuclein lesions in Lewy body diseases. Neurobiology of Aging. 26: 1183-92. PMID 15917102 DOI: 10.1016/J.Neurobiolaging.2004.10.006 |
0.316 |
|
| 2005 |
Moore DJ, Zhang L, Troncoso J, Lee MK, Hattori N, Mizuno Y, Dawson TM, Dawson VL. Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. Human Molecular Genetics. 14: 71-84. PMID 15525661 DOI: 10.1093/Hmg/Ddi007 |
0.308 |
|
| 2004 |
Li W, Lesuisse C, Xu Y, Troncoso JC, Price DL, Lee MK. Stabilization of alpha-synuclein protein with aging and familial parkinson's disease-linked A53T mutation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7400-9. PMID 15317865 DOI: 10.1523/Jneurosci.1370-04.2004 |
0.313 |
|
| 2004 |
Jankowsky JL, Fadale DJ, Anderson J, Xu GM, Gonzales V, Jenkins NA, Copeland NG, Lee MK, Younkin LH, Wagner SL, Younkin SG, Borchelt DR. Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase. Human Molecular Genetics. 13: 159-70. PMID 14645205 DOI: 10.1093/Hmg/Ddh019 |
0.327 |
|
| 2003 |
Bard F, Barbour R, Cannon C, Carretto R, Fox M, Games D, Guido T, Hoenow K, Hu K, Johnson-Wood K, Khan K, Kholodenko D, Lee C, Lee M, Motter R, et al. Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology. Proceedings of the National Academy of Sciences of the United States of America. 100: 2023-8. PMID 12566568 DOI: 10.1073/Pnas.0436286100 |
0.331 |
|
| 2002 |
Lazarov O, Lee M, Peterson DA, Sisodia SS. Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9785-93. PMID 12427834 DOI: 10.1523/Jneurosci.22-22-09785.2002 |
0.301 |
|
| 2002 |
Lee MK, Stirling W, Xu Y, Xu X, Qui D, Mandir AS, Dawson TM, Copeland NG, Jenkins NA, Price DL. Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 8968-73. PMID 12084935 DOI: 10.1073/Pnas.132197599 |
0.334 |
|
| 2002 |
Borchelt DR, Lee MK, Gonzales V, Slunt HH, Ratovitski T, Jenkins NA, Copeland NG, Price DL, Sisodia SS. Accumulation of proteolytic fragments of mutant presenilin 1 and accelerated amyloid deposition are co-regulated in transgenic mice. Neurobiology of Aging. 23: 171-7. PMID 11804700 DOI: 10.1016/S0197-4580(01)00280-9 |
0.323 |
|
| 2001 |
Dovey HF, John V, Anderson JP, Chen LZ, de Saint Andrieu P, Fang LY, Freedman SB, Folmer B, Goldbach E, Holsztynska EJ, Hu KL, Johnson-Wood KL, Kennedy SL, Kholodenko D, Knops JE, ... ... Lee M, et al. Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain. Journal of Neurochemistry. 76: 173-81. PMID 11145990 DOI: 10.1046/J.1471-4159.2001.00012.X |
0.308 |
|
| 2001 |
Lee MK, Price DL. Advances in genetic models of Parkinson's disease Clinical Neuroscience Research. 1: 456-466. DOI: 10.1016/S1566-2772(01)00024-X |
0.342 |
|
| 2000 |
Price DL, Wong PC, Markowska AL, Lee MK, Thinakaren G, Cleveland DW, Sisodia SS, Borchelt DR. The value of transgenic models for the study of neurodegenerative diseases. Annals of the New York Academy of Sciences. 920: 179-91. PMID 11193148 DOI: 10.1111/J.1749-6632.2000.Tb06920.X |
0.344 |
|
| 2000 |
Bard F, Cannon C, Barbour R, Burke RL, Games D, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Lieberburg I, Motter R, et al. Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease. Nature Medicine. 6: 916-9. PMID 10932230 DOI: 10.1038/78682 |
0.357 |
|
| 2000 |
Zaman SH, Parent A, Laskey A, Lee MK, Borchelt DR, Sisodia SS, Malinow R. Enhanced synaptic potentiation in transgenic mice expressing presenilin 1 familial Alzheimer's disease mutation is normalized with a benzodiazepine. Neurobiology of Disease. 7: 54-63. PMID 10671322 DOI: 10.1006/Nbdi.1999.0271 |
0.339 |
|
| 2000 |
Ishihara T, Hong M, Zhang B, Nakagawa Y, Lee MK, Trojanowski JQ, Lee VM. Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron. 24: 751-62. PMID 10595524 DOI: 10.1016/S0896-6273(00)81127-7 |
0.365 |
|
| 1999 |
Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Liao Z, Lieberburg I, Motter R, et al. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature. 400: 173-7. PMID 10408445 DOI: 10.1038/22124 |
0.359 |
|
| 1998 |
Wong PC, Borchelt DR, Lee MK, Pardo CA, Thinakaran G, Martin LJ, Sisodia SS, Price DL. Familial amyotrophic lateral sclerosis and Alzheimer's disease. Transgenic models. Advances in Experimental Medicine and Biology. 446: 145-59. PMID 10079842 DOI: 10.1007/978-1-4615-4869-0_9 |
0.351 |
|
| 1998 |
Borchelt DR, Wong PC, Becher MW, Pardo CA, Lee MK, Xu ZS, Thinakaran G, Jenkins NA, Copeland NG, Sisodia SS, Cleveland DW, Price DL, Hoffman PN. Axonal transport of mutant superoxide dismutase 1 and focal axonal abnormalities in the proximal axons of transgenic mice. Neurobiology of Disease. 5: 27-35. PMID 9702785 DOI: 10.1006/Nbdi.1998.0178 |
0.304 |
|
| 1998 |
Troncoso JC, Cataldo AM, Nixon RA, Barnett JL, Lee MK, Checler F, Fowler DR, Smialek JE, Crain B, Martin LJ, Kawas CH. Neuropathology of preclinical and clinical late-onset Alzheimer's disease. Annals of Neurology. 43: 673-6. PMID 9585365 DOI: 10.1002/Ana.410430519 |
0.31 |
|
| 1997 |
Borchelt DR, Ratovitski T, van Lare J, Lee MK, Gonzales V, Jenkins NA, Copeland NG, Price DL, Sisodia SS. Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron. 19: 939-45. PMID 9354339 DOI: 10.1016/S0896-6273(00)80974-5 |
0.364 |
|
| 1997 |
Lee MK, Borchelt DR, Kim G, Thinakaran G, Slunt HH, Ratovitski T, Martin LJ, Kittur A, Gandy S, Levey AI, Jenkins N, Copeland N, Price DL, Sisodia SS. Hyperaccumulation of FAD-linked presenilin 1 variants in vivo. Nature Medicine. 3: 756-60. PMID 9212102 DOI: 10.1038/Nm0797-756 |
0.359 |
|
| 1997 |
Bruijn LI, Becher MW, Lee MK, Anderson KL, Jenkins NA, Copeland NG, Sisodia SS, Rothstein JD, Borchelt DR, Price DL, Cleveland DW. ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. Neuron. 18: 327-38. PMID 9052802 DOI: 10.1016/S0896-6273(00)80272-X |
0.338 |
|
| 1997 |
Johnson-Wood K, Lee M, Motter R, Hu K, Gordon G, Barbour R, Khan K, Gordon M, Tan H, Games D, Lieberburg I, Schenk D, Seubert P, McConlogue L. Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. 94: 1550-5. PMID 9037091 DOI: 10.1073/Pnas.94.4.1550 |
0.319 |
|
| 1997 |
Citron M, Westaway D, Xia W, Carlson G, Diehl T, Levesque G, Johnson-Wood K, Lee M, Seubert P, Davis A, Kholodenko D, Motter R, Sherrington R, Perry B, Yao H, et al. Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nature Medicine. 3: 67-72. PMID 8986743 DOI: 10.1038/Nm0197-67 |
0.32 |
|
| 1996 |
Levitan D, Doyle TG, Brousseau D, Lee MK, Thinakaran G, Slunt HH, Sisodia SS, Greenwald I. Assessment of normal and mutant human presenilin function in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 93: 14940-4. PMID 8962160 DOI: 10.1073/Pnas.93.25.14940 |
0.319 |
|
| 1996 |
Price DL, Becher MW, Wong PC, Borchelt DR, Lee MK, Sisodia SS. Inherited neurodegenerative diseases and transgenic models. Brain Pathology (Zurich, Switzerland). 6: 467-80. PMID 8944317 DOI: 10.1111/J.1750-3639.1996.Tb00876.X |
0.338 |
|
| 1996 |
Borchelt DR, Thinakaran G, Eckman CB, Lee MK, Davenport F, Ratovitsky T, Prada CM, Kim G, Seekins S, Yager D, Slunt HH, Wang R, Seeger M, Levey AI, Gandy SE, et al. Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron. 17: 1005-13. PMID 8938131 DOI: 10.1016/S0896-6273(00)80230-5 |
0.348 |
|
| 1996 |
Lee MK, Borchelt DR, Wong PC, Sisodia SS, Price DL. Transgenic models of neurodegenerative diseases. Current Opinion in Neurobiology. 6: 651-60. PMID 8937830 DOI: 10.1016/S0959-4388(96)80099-7 |
0.351 |
|
| 1996 |
Lee MK, Slunt HH, Martin LJ, Thinakaran G, Kim G, Gandy SE, Seeger M, Koo E, Price DL, Sisodia SS. Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 7513-25. PMID 8922407 DOI: 10.1523/Jneurosci.16-23-07513.1996 |
0.311 |
|
| 1996 |
Marszalek JR, Williamson TL, Lee MK, Xu Z, Hoffman PN, Becher MW, Crawford TO, Cleveland DW. Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport. The Journal of Cell Biology. 135: 711-24. PMID 8909545 DOI: 10.1083/Jcb.135.3.711 |
0.306 |
|
| 1996 |
Cleveland DW, Bruijn LI, Wong PC, Marszalek JR, Vechio JD, Lee MK, Xu XS, Borchelt DR, Sisodia SS, Price DL. Mechanisms of selective motor neuron death in transgenic mouse models of motor neuron disease. Neurology. 47: S54-61; discussion S. PMID 8858052 DOI: 10.1212/Wnl.47.4_Suppl_2.54S |
0.353 |
|
| 1996 |
Thinakaran G, Borchelt DR, Lee MK, Slunt HH, Spitzer L, Kim G, Ratovitsky T, Davenport F, Nordstedt C, Seeger M, Hardy J, Levey AI, Gandy SE, Jenkins NA, Copeland NG, et al. Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron. 17: 181-90. PMID 8755489 DOI: 10.1016/S0896-6273(00)80291-3 |
0.332 |
|
| 1996 |
Bruijn LJ, Becher MW, Lee MK, Cleveland DW, Price DL. Characterization Of Intracytoplasmic Abnormalities In Low Expressor Sod1 Transgenic Mice With Motor Neuron Disease Journal of Neuropathology and Experimental Neurology. 55: 632. DOI: 10.1097/00005072-199605000-00119 |
0.321 |
|
| 1996 |
Thinakaran G, Doan A, Lee M, Slunt H, Savage M, Greenberg B, Wang R, Price D, Sisodia S. 443 Characterization of presenilin 1 (PS1) with mutations linked to familial Alzheimer's disease: Metabolism, topology and influence on Aβ generation Neurobiology of Aging. 17: S110. DOI: 10.1016/S0197-4580(96)80445-3 |
0.314 |
|
| 1996 |
Schenk D, Dovey R, Games D, Johnson-Wood K, Knops J, Lee M, McConlogue L, Lieberburg I, Seubert P, Sinha S. 175 Inhibition of β- and γ-secretases as therapeutic targets for Alzheimer's disease Neurobiology of Aging. 17: S45. DOI: 10.1016/S0197-4580(96)80177-1 |
0.311 |
|
| 1996 |
Borchelt D, Lee M, Thinakaran G, Wong PC, Slunt HHHH, Ratovitski T, Kim G, Jenkins NA, Copeland NG, Price D. 95 Synthesis and metabolism of presenilin 1 with mutations linked to familial Alzheimer's disease in transgenic mice Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80097-2 |
0.325 |
|
| 1996 |
Wong PC, Borchelt DR, Lee MK, Pardo CA, Sisodia SS, Cleveland DW, Koliatsos VE, Price DL. Transgenic and gene-targeting approaches to model disorders of motor neurons Seminars in Neuroscience. 8: 163-169. DOI: 10.1006/Smns.1996.0021 |
0.331 |
|
| 1995 |
Borchelt DR, Guarnieri M, Wong PC, Lee MK, Slunt HS, Xu ZS, Sisodia SS, Price DL, Cleveland DW. Superoxide dismutase 1 subunits with mutations linked to familial amyotrophic lateral sclerosis do not affect wild-type subunit function. The Journal of Biological Chemistry. 270: 3234-8. PMID 7852409 DOI: 10.1074/Jbc.270.7.3234 |
0.304 |
|
| 1995 |
Knops J, Suomensaari S, Lee M, McConlogue L, Seubert P, Sinha S. Cell-type and amyloid precursor protein-type specific inhibition of A beta release by bafilomycin A1, a selective inhibitor of vacuolar ATPases. The Journal of Biological Chemistry. 270: 2419-22. PMID 7852298 DOI: 10.1074/Jbc.270.6.2419 |
0.329 |
|
| 1995 |
Vigo-Pelfrey C, Seubert P, Barbour R, Blomquist C, Lee M, Lee D, Coria F, Chang L, Miller B, Lieberburg I. Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease. Neurology. 45: 788-93. PMID 7723971 DOI: 10.1212/Wnl.45.4.788 |
0.302 |
|
| 1995 |
Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron. 14: 1105-16. PMID 7605627 DOI: 10.1016/0896-6273(95)90259-7 |
0.356 |
|
| 1994 |
Lee MK, Marszalek JR, Cleveland DW. A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease. Neuron. 13: 975-88. PMID 7946341 DOI: 10.1016/0896-6273(94)90263-1 |
0.314 |
|
| 1994 |
Lee MK, Cleveland DW. Neurofilament function and dysfunction: involvement in axonal growth and neuronal disease. Current Opinion in Cell Biology. 6: 34-40. PMID 7513179 DOI: 10.1016/0955-0674(94)90113-9 |
0.319 |
|
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