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Robert M. Moriarty - Publications

Affiliations: 
University of Illinois at Chicago, Chicago, IL, United States 
Area:
Organic Chemistry, Pharmaceutical Chemistry, Biochemistry
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Chang J, Schul W, Butters TD, Yip A, Liu B, Goh A, Lakshminarayana SB, Alonzi D, Reinkensmeier G, Pan X, Qu X, Weidner JM, Wang L, Yu W, Borune N, ... ... Moriarty R, et al. Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo. Antiviral Research. 89: 26-34. PMID 21073903 DOI: 10.1016/J.Antiviral.2010.11.002  0.56
2010 Moriarty RM, Tyagi S. Metal-free intramolecular aziridination of alkenes using hypervalent iodine based sulfonyliminoiodanes. Organic Letters. 12: 364-6. PMID 20000588 DOI: 10.1021/Ol9026655  0.537
2009 Chang J, Wang L, Ma D, Qu X, Guo H, Xu X, Mason PM, Bourne N, Moriarty R, Gu B, Guo JT, Block TM. Novel imino sugar derivatives demonstrate potent antiviral activity against flaviviruses. Antimicrobial Agents and Chemotherapy. 53: 1501-8. PMID 19223639 DOI: 10.1128/Aac.01457-08  0.31
2008 Naithani R, Huma LC, Holland LE, Shukla D, McCormick DL, Mehta RG, Moriarty RM. Antiviral activity of phytochemicals: a comprehensive review. Mini Reviews in Medicinal Chemistry. 8: 1106-33. PMID 18855727 DOI: 10.2174/138955708785909943  0.308
2008 Moriarty RM, Tyagi S, Ivanov D, Constantinescu M. The mechanism of 1,4 alkyl group migration in hypervalent halonium ylides: the stereochemical course. Journal of the American Chemical Society. 130: 7564-5. PMID 18491909 DOI: 10.1021/Ja802735F  0.567
2008 Naithani R, Huma LC, Moriarty RM, McCormick DL, Mehta RG. Comprehensive review of cancer chemopreventive agents evaluated in experimental carcinogenesis models and clinical trials. Current Medicinal Chemistry. 15: 1044-71. PMID 18473802 DOI: 10.2174/092986708784221403  0.321
2007 Moriarty RM, Naithani R, Surve B. Organosulfur compounds in cancer chemoprevention. Mini Reviews in Medicinal Chemistry. 7: 827-38. PMID 17692044 DOI: 10.2174/138955707781387939  0.751
2007 Murillo G, Hirschelman WH, Ito A, Moriarty RM, Kinghorn AD, Pezzuto JM, Mehta RG. Zapotin, a phytochemical present in a Mexican fruit, prevents colon carcinogenesis. Nutrition and Cancer. 57: 28-37. PMID 17516860 DOI: 10.1080/01635580701268097  0.714
2006 Moriarty RM, Mitan CI, Branza-Nichita N, Phares KR, Parrish D. exo-Imino to endo-iminocyclitol rearrangement. A general route to five-membered antiviral azasugars. Organic Letters. 8: 3465-7. PMID 16869636 DOI: 10.1021/Ol061071R  0.312
2006 Moriarty RM, Grubjesic S, Surve BC, Chandersekera SN, Prakash O, Naithani R. Synthesis of Abyssinone II and related compounds as potential chemopreventive agents. European Journal of Medicinal Chemistry. 41: 263-7. PMID 16330130 DOI: 10.1016/J.Ejmech.2005.09.008  0.714
2006 Moriarty RM, Naithani R, Kosmeder J, Prakash O. Cancer chemopreventive activity of sulforamate derivatives. European Journal of Medicinal Chemistry. 41: 121-4. PMID 16300858 DOI: 10.1016/J.Ejmech.2005.10.002  0.356
2005 Moriarty RM, Albinescu D. Synthesis of 1alpha-hydroxyvitamin D5 using a modified two wavelength photolysis for vitamin D formation. The Journal of Organic Chemistry. 70: 7624-8. PMID 16149791 DOI: 10.1021/Jo050853F  0.733
2004 Moriarty RM, Pavlović D. Synthesis of 1,4-annulated cyclooctatetraenophanes based on a novel cubane building block approach. The Journal of Organic Chemistry. 69: 5501-4. PMID 15287808 DOI: 10.1021/Jo049643D  0.308
2004 Li Y, Grubjesic S, Nikolic D, Zhu D, Kosmeder JW, Moriarty RM, Pezzuto JM, Van Breemen RB. In vitro assessment of intestinal permeability and hepatic metabolism of 4'-bromoflavone, a promising cancer chemopreventive agent. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 34: 535-47. PMID 15277014 DOI: 10.1080/00498250410001713159  0.749
2004 Moriarty RM, Rani N, Enache LA, Rao MS, Batra H, Guo L, Penmasta RA, Staszewski JP, Tuladhar SM, Prakash O, Crich D, Hirtopeanu A, Gilardi R. The intramolecular asymmetric Pauson-Khand cyclization as a novel and general stereoselective route to benzindene prostacyclins: synthesis of UT-15 (treprostinil). The Journal of Organic Chemistry. 69: 1890-902. PMID 15058934 DOI: 10.1021/Jo0347720  0.315
2002 Grubjesic S, Moriarty RM, Pezzuto JM. Aromatase inhibitors Expert Opinion On Therapeutic Patents. 12: 1647-1661. DOI: 10.1517/13543776.12.11.1647  0.74
2000 Mehta R, Hawthorne M, Uselding L, Albinescu D, Moriarty R, Christov K. Prevention of N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats by 1α-hydroxyvitamin D5 Journal of the National Cancer Institute. 92: 1836-1840. PMID 11078761 DOI: 10.1093/Jnci/92.22.1836  0.727
2000 Lazzaro G, Agadir A, Qing W, Poria M, Mehta RR, Moriarty RM, Das Gupta TK, Zhang XK, Mehta RG. Induction of differentiation by 1alpha-hydroxyvitamin D(5) in T47D human breast cancer cells and its interaction with vitamin D receptors. European Journal of Cancer (Oxford, England : 1990). 36: 780-6. PMID 10762752 DOI: 10.1016/S0959-8049(00)00016-2  0.332
1997 Mehta RG, Moriarty RM, Mehta RR, Penmasta R, Lazzaro G, Constantinou A, Guo L. Prevention of preneoplastic mammary lesion development by a novel vitamin D analogue, 1alpha-hydroxyvitamin D5. Journal of the National Cancer Institute. 89: 212-8. PMID 9017001 DOI: 10.1093/Jnci/89.3.212  0.338
1997 Moriarty RM, Prakash OM. Synthesis of Heterocyclic Compounds Using Organohypervalent Iodine Reagents Advances in Heterocyclic Chemistry. 69: 1-87. DOI: 10.1016/S0065-2725(08)60080-X  0.347
1997 Moriarty RM, May EJ, Prakash O. Intramolecular cyclization of aryl substituted iodonium ylides with copper(I) chloride Tetrahedron Letters. 38: 4333-4336. DOI: 10.1016/S0040-4039(97)00967-2  0.308
1995 Mehta RG, Liu J, Constantinou A, Thomas CF, Hawthorne M, You M, Gerhüser C, Pezzuto JM, Moon RC, Moriarty RM. Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage. Carcinogenesis. 16: 399-404. PMID 7859373 DOI: 10.1093/Carcin/16.2.399  0.364
1995 Moriarty RM, Brumer H. Toward a general synthesis of A-ring trihydroxylated vitamin D analogs: Synthesis of an A-ring synthon of ED-71 from d-arabinose Tetrahedron Letters. 36: 9265-9268. DOI: 10.1016/0040-4039(95)02008-D  0.347
1995 Moriarty RM, Kim J, Brumer H. A general synthetic route to A-ring hydroxylated vitamin D analogs from pentoses Tetrahedron Letters. 36: 51-54. DOI: 10.1016/0040-4039(94)02209-T  0.344
1995 Moriarty RM, Levy SG. Synthesis and resolution of 2-arylalkyl-2-(tetrazol-5-yl)-N-arylalkyl-carboxamides. A new class of chiral sterically hindered tetrazole derivatives† Journal of Heterocyclic Chemistry. 32: 155-160. DOI: 10.1002/Jhet.5570320125  0.31
1993 Moriarty RM, Kim J, Guo L. Intramolecular cyclopropanation using iodonium ylides. The 3,5-cyclovitamin D ring A synthon Tetrahedron Letters. 34: 4129-4132. DOI: 10.1016/S0040-4039(00)60509-9  0.328
1992 Moriarty RM, Kim J, Penmasta R. A convenient synthesis of 1α,25-dihydroxy-28-norvitamin D2 Tetrahedron Letters. 33: 3741-3744. DOI: 10.1016/0040-4039(92)80013-A  0.367
1990 Moriarty RM, Hopkins TE, Prakash I, Vaid BK, Vaid RK. Hyper valent iodine oxidation of amines in the presence of nitroso compounds: A method for the preparation of unsymmetrically substituted azoxy compounds Synthetic Communications. 20: 2353-2357. DOI: 10.1080/00397919008053180  0.32
1989 Moriarty RM, Khosrowshahi JS. Functionalization of Cubanes and Homocubanes via Oxidative Displacement of Iodine Using Hypervalent Iodine Synthetic Communications. 19: 1395-1403. DOI: 10.1080/00397918908054549  0.31
1989 Moriarty RM, Penmasta R, Awasthi AK, Epa WR, Prakash I. Reaction of [hydroxy(tosyloxy)iodo]benzene and [hydroxy(mesyloxy)iodo]benzene with trimethylsilyl enol ethers. A new general method for .alpha.-sulfonyloxylation of carbonyl compounds Journal of Organic Chemistry. 54: 1101-1104. DOI: 10.1021/Jo00266A020  0.318
1989 Moriarty RM, Epa WR, Penmasta R, Awasthi AK. Hypervalent iodine oxidation of trimethylsilyl enol ethers of ketones: A direct synthesis of α-keto triflates Tetrahedron Letters. 30: 667-670. DOI: 10.1016/S0040-4039(01)80277-X  0.317
1987 Moriarty RM, Prakash I, Penrnasta R. An Improved Synthesis of Ethyl Azodicarboxylate and 1,2,4-Triazoline-3,5-Diones Using Hypervalent Iodine Oxidation Synthetic Communications. 17: 409-413. DOI: 10.1080/00397918708063918  0.32
1985 Moriarty RM, Prakash O, Duncan MP. Synthesis of 3,2′:5′,3′′-Terthiophene and 2,5-DI(3′-Thienyl)Furan Cheminform. 17: 789-795. DOI: 10.1002/Chin.198603179  0.319
1981 Moriarty RM, Hu H. Hypervalent iodine in organic synthesis. A new route to α-functionalized carboxylate esters. Tetrahedron Letters. 22: 2747-2750. DOI: 10.1016/S0040-4039(01)90541-6  0.303
1975 Moriarty RM, Paaren H, Gilmore J. Synthesis Of C(19)Acetoxy Precalciferol, And Its Conversion Into The Vitamin D3 Analogue Cheminform. 6. DOI: 10.1002/Chin.197507477  0.329
1974 Moriarty RM, Paaren H, Gilmore J. Synthesis of C(19)-acetoxy precalciferol3 and its conversion into the vitamin D3 analogue Journal of the Chemical Society, Chemical Communications. 927-927. DOI: 10.1039/C39740000927  0.359
1962 Vandenheuvel WJA, Moriarty RM, Wallis ES. The solvolysis of 4,4-dimethylcholesteryl p-toluenesulfonate. III. A kinetic study Journal of Organic Chemistry. 27: 725-726. DOI: 10.1021/Jo01050A005  0.594
1960 Moriarty R, Wallis E. Correction. Solvolysis of 4,4-Dimethylcholesteryl-p-toluenesulfonate. II. Journal of Organic Chemistry. 25: 2262-2262. DOI: 10.1021/Jo01082A638  0.592
1959 Moriarty RM, Wallis ES. Solvolysis of 4,4-dimethylcholesteryl-p-toluenesulfonate. II Journal of Organic Chemistry. 24: 1987-1989. DOI: 10.1021/Jo01094A041  0.593
1959 Moriarty RM, Wallis ES. The Solvolysis of 4,4-Dimethylcholesteryl p-Toluenesulfonate Journal of Organic Chemistry. 24: 1274-1278. DOI: 10.1021/Jo01091A029  0.578
1958 Beyler RE, Moriarty RM, Hoffman F, Sarett LH. 17,20;20,21-BISMETHYLENEDIOXY STEROIDS Journal of the American Chemical Society. 80: 1517-1518. DOI: 10.1021/ja01539a059  0.488
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