| Year |
Citation |
Score |
| 2021 |
Tellez CS, Picchi MA, Juri D, Do K, Desai DH, Amin SG, Hutt JA, Filipczak PT, Belinsky SA. Chromatin remodeling by the histone methyltransferase EZH2 drives lung pre-malignancy and is a target for cancer prevention. Clinical Epigenetics. 13: 44. PMID 33632299 DOI: 10.1186/s13148-021-01034-4 |
0.441 |
|
| 2020 |
Tessema M, Tassew DD, Yingling CM, Do K, Picchi MA, Wu G, Petersen H, Randell S, Lin Y, Belinsky SA, Tesfaigzi Y. Identification of novel epigenetic abnormalities as sputum biomarkers for lung cancer risk among smokers and COPD patients. Lung Cancer (Amsterdam, Netherlands). 146: 189-196. PMID 32559455 DOI: 10.1016/J.Lungcan.2020.05.017 |
0.361 |
|
| 2020 |
Kuehl PJ, Tellez CS, Grimes MJ, March TH, Tessema M, Revelli DA, Mallis LM, Dye WW, Sniegowski T, Badenoch A, Burke M, Dubose D, Vodak DT, Picchi MA, Belinsky SA. 5-Azacytidine inhaled dry powder formulation profoundly improves pharmacokinetics and efficacy for lung cancer therapy through genome reprogramming. British Journal of Cancer. PMID 32103148 DOI: 10.1038/S41416-020-0765-2 |
0.3 |
|
| 2019 |
Wang Q, Wang P, Zhang L, Tessema M, Bai L, Xu X, Li Q, Zheng X, Saxton B, Chen W, Willink R, Li Z, Zhang L, Belinsky SA, Wang X, et al. Epigenetic Regulation of RIP3 Suppresses Necroptosis and Increases Resistance to Chemotherapy in NonSmall Cell Lung Cancer. Translational Oncology. 13: 372-382. PMID 31887632 DOI: 10.1016/j.tranon.2019.11.011 |
0.357 |
|
| 2019 |
Teneng I, Picchi MA, Leng S, Dagucon CP, Ramalingam S, Tellez CS, Belinsky SA. DNA-PKc deficiency drives pre-malignant transformation by reducing DNA repair capacity in concert with reprogramming the epigenome in human bronchial epithelial cells. Dna Repair. 79: 1-9. PMID 31055244 DOI: 10.1016/j.dnarep.2019.04.006 |
0.402 |
|
| 2019 |
Filipczak PT, Leng S, Tellez CS, Do KC, Grimes MJ, Thomas CL, Walton-Filipczak SR, Picchi MA, Belinsky SA. p53-suppressed oncogene TET1 prevents cellular aging in lung cancer. Cancer Research. PMID 30622117 DOI: 10.1158/0008-5472.CAN-18-1234 |
0.395 |
|
| 2019 |
Kuehl P, Tellez C, Grimes M, Burke M, Badenoch A, Dubose D, Belinsky S. MA17.09 5-Azacytidine Inhaled Dry Powder Formulation Profoundly Improves Pharmacokinetics and Efficacy for Lung Cancer Therapy Journal of Thoracic Oncology. 14: S319-S320. DOI: 10.1016/J.Jtho.2019.08.643 |
0.389 |
|
| 2018 |
Tsoyi K, Osorio JC, Chu SG, Fernandez IE, Poli S, Sholl L, Cui Y, Tellez CS, Siegfried JM, Belinsky SA, Perrella MA, El-Chemaly S, Rosas IO. Lung Adenocarcinoma Syndecan-2 Potentiates Cell Invasiveness. American Journal of Respiratory Cell and Molecular Biology. PMID 30562054 DOI: 10.1165/Rcmb.2018-0118Oc |
0.369 |
|
| 2018 |
Tessema M, Rossi MR, Picchi MA, Yingling CM, Lin Y, Ramalingam SS, Belinsky SA. Common cancer-driver mutations and their association with abnormally methylated genes in lung adenocarcinoma from never-smokers. Lung Cancer (Amsterdam, Netherlands). 123: 99-106. PMID 30089603 DOI: 10.1016/j.lungcan.2018.07.011 |
0.49 |
|
| 2018 |
Kuehl PJ, Grimes MJ, Dubose D, Burke M, Revelli DA, Gigliotti AP, Belinsky SA, Tessema M. Inhalation delivery of topotecan is superior to intravenous exposure for suppressing lung cancer in a preclinical model. Drug Delivery. 25: 1127-1136. PMID 29779406 DOI: 10.1080/10717544.2018.1469688 |
0.358 |
|
| 2018 |
Leng S, Diergaarde B, Picchi MA, Wilson DO, Gilliland FD, Yuan JM, Siegfried JM, Belinsky SA. Gene Promoter Hypermethylation Detected in Sputum Predicts FEV1 Decline and All-cause Mortality in Smokers. American Journal of Respiratory and Critical Care Medicine. PMID 29437466 DOI: 10.1164/Rccm.201708-1659Oc |
0.38 |
|
| 2017 |
Leng S, Picchi MA, Kang H, Wu G, Filipczak PT, Juri DE, Zhang X, Gauderman WJ, Gilliland FD, Belinsky SA. Dietary nutrient intake, ethnicity, and epigenetic silencing of lung cancer genes detected in sputum in New Mexican smokers. Cancer Prevention Research (Philadelphia, Pa.). PMID 29118161 DOI: 10.1158/1940-6207.Capr-17-0196 |
0.412 |
|
| 2017 |
Leng S, Wu G, Klinge DM, Thomas CL, Casas E, Picchi MA, Stidley CA, Lee SJ, Aisner S, Siegfried JM, Ramalingam S, Khuri FR, Karp DD, Belinsky SA. Gene methylation biomarkers in sputum as a classifier for lung cancer risk. Oncotarget. 8: 63978-63985. PMID 28969046 DOI: 10.18632/Oncotarget.19255 |
0.441 |
|
| 2017 |
Tessema M, Yingling CM, Picchi MA, Wu G, Ryba T, Lin Y, Bungum AO, Edell ES, Spira A, Belinsky SA. ANK1 Methylation Regulates Expression of MicroRNA-486-5p and Discriminates Lung tumors by Histology and Smoking Status. Cancer Letters. PMID 28965852 DOI: 10.1016/J.Canlet.2017.09.038 |
0.469 |
|
| 2017 |
Belinsky SA, Leng S, Wu G, Thomas CL, Picchi MA, Lee SJ, Aisner S, Ramalingam S, Khuri FR, Karp DD. Gene Methylation Biomarkers in Sputum and Plasma as Predictors for Lung Cancer Recurrence. Cancer Prevention Research (Philadelphia, Pa.). PMID 28904059 DOI: 10.1158/1940-6207.CAPR-17-0177 |
0.454 |
|
| 2017 |
Leng S, Wu G, Klinge DM, Thomas CL, Casas E, Picchi MA, Stidley CA, Lee SJ, Aisner S, Siegfried JM, Ramalingam S, Khuri FR, Karp DD, Belinsky SA. Gene methylation biomarkers in sputum as a classifier for lung cancer risk. Oncotarget. PMID 28754865 DOI: 10.18632/oncotarget.19255 |
0.441 |
|
| 2017 |
Xu X, Chen W, Leng S, Padilla MT, Saxton B, Hutt J, Tessema M, Kato K, Kim KC, Belinsky SA, Lin Y. Muc1 knockout potentiates murine lung carcinogenesis involving an epiregulin-mediated EGFR activation feedback loop. Carcinogenesis. PMID 28472347 DOI: 10.1093/carcin/bgx039 |
0.393 |
|
| 2016 |
Hulbert A, Jusue Torres I, Stark A, Chen C, Rodgers K, Lee B, Griffin C, Yang A, Huang P, Wrangle J, Belinsky SA, Wang TH, Yang SC, Baylin SB, Brock MV, et al. Early Detection of Lung Cancer using DNA Promoter Hypermethylation in Plasma and Sputum. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27729459 DOI: 10.1158/1078-0432.Ccr-16-1371 |
0.391 |
|
| 2016 |
Tellez CS, Juri DE, Do KC, Picchi MA, Wang T, Liu G, Spira AE, Belinsky SA. MiR-196b is epigenetically silenced during the pre-malignant stage of lung carcinogenesis. Cancer Research. PMID 27302168 DOI: 10.1158/0008-5472.CAN-15-3367 |
0.323 |
|
| 2016 |
Gong Z, Wang D, Espinal A, Hu Q, Sucheston-Campbell L, Tang L, Freudenheim J, Shields P, Morrison C, Belinsky S, Liu S, Demissie K, Higgins M, Ambrosone C. Abstract A31: Genome-wide microRNA profiling analysis of breast cancer among African American and European American women Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-A31 |
0.316 |
|
| 2016 |
Rybicki BA, Rundle A, Kryvenko O, Chitale D, Belinsky S, Tang D. Abstract 2635: Methylation in benign prostate and risk of disease progression in men subsequently diagnosed with prostate cancer Cancer Research. 76: 2635-2635. DOI: 10.1158/1538-7445.Am2016-2635 |
0.353 |
|
| 2016 |
Leng S, Guillen H, Tellez C, Picchi M, Swenberg J, Gilliland F, Belinsky S. Abstract 2564: Cis and trans quantitative trait loci for MGMT promoter hypermethylation detected in lung exfoliated cells collected in sputum from smokers Epidemiology. 76: 2564-2564. DOI: 10.1158/1538-7445.Am2016-2564 |
0.426 |
|
| 2015 |
Leng S, Thomas CL, Snider AM, Picchi MA, Chen W, Willis DG, Carr TG, Krzeminski J, Desai D, Shantu A, Lin Y, Jacobson MR, Belinsky SA. Radon Exposure, IL-6 Promoter Variants, and Lung Squamous Cell Carcinoma in Former Uranium Miners. Environmental Health Perspectives. PMID 26372664 DOI: 10.1289/ehp.1409437 |
0.303 |
|
| 2015 |
Tessema M, Yingling CM, Picchi MA, Wu G, Liu Y, Weissfeld JL, Siegfried JM, Tesfaigzi Y, Belinsky SA. Epigenetic Repression of CCDC37 and MAP1B Links Chronic Obstructive Pulmonary Disease to Lung Cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 1181-8. PMID 26200272 DOI: 10.1097/Jto.0000000000000592 |
0.31 |
|
| 2015 |
Leng S, Wu G, Collins LB, Thomas CL, Tellez CS, Jauregui AR, Picchi MA, Zhang X, Juri DE, Desai D, Amin SG, Crowell RE, Stidley CA, Liu Y, Swenberg JA, ... ... Belinsky SA, et al. Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung. Cancer Research. PMID 26183928 DOI: 10.1158/0008-5472.Can-15-0243 |
0.411 |
|
| 2015 |
Leng S, Liu Y, Weissfeld JL, Thomas CL, Han Y, Picchi MA, Edlund CK, Willink RP, Gaither Davis AL, Do KC, Nukui T, Zhang X, Burki EA, Van Den Berg D, Romkes M, ... ... Belinsky SA, et al. 15q12 variants, sputum gene promoter hypermethylation, and lung cancer risk: a GWAS in smokers. Journal of the National Cancer Institute. 107. PMID 25713168 DOI: 10.1093/Jnci/Djv035 |
0.449 |
|
| 2015 |
Belinsky SA. Unmasking the lung cancer epigenome. Annual Review of Physiology. 77: 453-74. PMID 25668024 DOI: 10.1146/annurev-physiol-021014-072018 |
0.495 |
|
| 2015 |
Meek PM, Sood A, Petersen H, Belinsky SA, Tesfaigzi Y. Epigenetic change (GATA-4 gene methylation) is associated with health status in chronic obstructive pulmonary disease. Biological Research For Nursing. 17: 191-8. PMID 24973415 DOI: 10.1177/1099800414538113 |
0.389 |
|
| 2015 |
Teneng I, Tellez CS, Picchi MA, Klinge DM, Yingling CM, Snider AM, Liu Y, Belinsky SA. Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer. Oncogene. 34: 621-30. PMID 24469050 DOI: 10.1038/onc.2013.580 |
0.554 |
|
| 2015 |
Rybicki B, Jankowski M, Do K, Chitale D, Trudeau S, Rundle A, Belinsky S, Tang D. Abstract A07: Methylation of RARB in prediagnosis benign tissue and risk of disease progression in men subsequently diagnosed with prostate cancer Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-A07 |
0.368 |
|
| 2014 |
Tessema M, Yingling CM, Snider AM, Do K, Juri DE, Picchi MA, Zhang X, Liu Y, Leng S, Tellez CS, Belinsky SA. GATA2 is epigenetically repressed in human and mouse lung tumors and is not requisite for survival of KRAS mutant lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 784-93. PMID 24807155 DOI: 10.1097/JTO.0000000000000165 |
0.422 |
|
| 2014 |
Tellez CS, Grimes MJ, Picchi MA, Liu Y, March TH, Reed MD, Oganesian A, Taverna P, Belinsky SA. SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome. International Journal of Cancer. Journal International Du Cancer. 135: 2223-31. PMID 24668305 DOI: 10.1002/ijc.28865 |
0.511 |
|
| 2014 |
Wrangle J, Machida EO, Danilova L, Hulbert A, Franco N, Zhang W, Glöckner SC, Tessema M, Van Neste L, Easwaran H, Schuebel KE, Licchesi J, Hooker CM, Ahuja N, Amano J, ... Belinsky SA, et al. Functional identification of cancer-specific methylation of CDO1, HOXA9, and TAC1 for the diagnosis of lung cancer Clinical Cancer Research. 20: 1856-1864. PMID 24486589 DOI: 10.1158/1078-0432.Ccr-13-2109 |
0.36 |
|
| 2014 |
Bruse S, Petersen H, Weissfeld J, Picchi M, Willink R, Do K, Siegfried J, Belinsky SA, Tesfaigzi Y. Increased methylation of lung cancer-associated genes in sputum DNA of former smokers with chronic mucous hypersecretion. Respiratory Research. 15: 2. PMID 24405663 DOI: 10.1186/1465-9921-15-2 |
0.477 |
|
| 2014 |
Tessema M, Yingling CM, Liu Y, Tellez CS, Van Neste L, Baylin SS, Belinsky SA. Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers. Carcinogenesis. 35: 1248-57. PMID 24398667 DOI: 10.1093/carcin/bgt494 |
0.523 |
|
| 2014 |
Kusko R, Garrison C, Wang T, Campbell J, Perez-Rogers J, Luo L, Beane J, Liu G, Kadara H, Belinsky S, Lenburg ME, Spira A. Abstract 3554: Gene and miRNA expression networks specific to never smoker lung adenocarcinoma Cancer Research. 74: 3554-3554. DOI: 10.1158/1538-7445.Am2014-3554 |
0.448 |
|
| 2014 |
Statt S, Thai P, Chen C, Cheng Y, Belinsky S, Wu R. Abstract 1469: Functional roles of SCAL1 expression in lung cancer and progression Cancer Research. 74: 1469-1469. DOI: 10.1158/1538-7445.Am2014-1469 |
0.493 |
|
| 2013 |
Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O'Hara C, ... ... Belinsky SA, et al. MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 18946-51. PMID 24158479 DOI: 10.1073/Pnas.1220319110 |
0.503 |
|
| 2013 |
Reed MD, Tellez CS, Grimes MJ, Picchi MA, Tessema M, Cheng YS, March TH, Kuehl PJ, Belinsky SA. Aerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model. British Journal of Cancer. 109: 1775-81. PMID 24045660 DOI: 10.1038/bjc.2013.575 |
0.409 |
|
| 2013 |
Leng S, Liu Y, Thomas CL, Gauderman WJ, Picchi MA, Bruse SE, Zhang X, Flores KG, Van Den Berg D, Stidley CA, Gilliland FD, Belinsky SA. Native American ancestry affects the risk for gene methylation in the lungs of Hispanic smokers from New Mexico. American Journal of Respiratory and Critical Care Medicine. 188: 1110-6. PMID 24032348 DOI: 10.1164/Rccm.201305-0925Oc |
0.457 |
|
| 2013 |
Karp DD, Lee SJ, Keller SM, Wright GS, Aisner S, Belinsky SA, Johnson DH, Johnston MR, Goodman G, Clamon G, Okawara G, Marks R, Frechette E, McCaskill-Stevens W, Lippman SM, et al. Randomized, double-blind, placebo-controlled, phase III chemoprevention trial of selenium supplementation in patients with resected stage I non-small-cell lung cancer: ECOG 5597. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 4179-87. PMID 24002495 DOI: 10.1200/JCO.2013.49.2173 |
0.326 |
|
| 2013 |
Leng S, Picchi MA, Liu Y, Thomas CL, Willis DG, Bernauer AM, Carr TG, Mabel PT, Han Y, Amos CI, Lin Y, Stidley CA, Gilliland FD, Jacobson MR, Belinsky SA. Genetic variation in SIRT1 affects susceptibility of lung squamous cell carcinomas in former uranium miners from the Colorado plateau. Carcinogenesis. 34: 1044-50. PMID 23354305 DOI: 10.1093/Carcin/Bgt024 |
0.328 |
|
| 2013 |
Wang T, Campbell J, Kusko R, Luo L, Tellez C, Liu G, Xiao J, Lenburg M, Belinsky S, Spira A. Abstract 1948: Shared and distinct microRNA-expression alterations in lung adenocarcinoma from smokers vs. nonsmokers. Cancer Research. 73: 1948-1948. DOI: 10.1158/1538-7445.Am2013-1948 |
0.406 |
|
| 2013 |
Van Neste L, Moreau F, Kelley M, Belinsky S, Bigley J, Van Criekinge W. MC13-0087 Epigenetic assay detects early stage non-small cell lung cancer in sputum European Journal of Cancer. 49: S36. DOI: 10.1016/S0959-8049(13)70191-6 |
0.342 |
|
| 2012 |
Bruce VR, Belinsky SA, Gott K, Liu Y, March T, Scott B, Wilder J. Low-dose gamma-radiation inhibits benzo[a]pyrene-induced lung adenoma development in a/j mice. Dose-Response : a Publication of International Hormesis Society. 10: 516-26. PMID 23304102 DOI: 10.2203/dose-response.12-040.Bruce |
0.308 |
|
| 2012 |
Flores KG, Stidley CA, Mackey AJ, Picchi MA, Stabler SP, Siegfried JM, Byers T, Berwick M, Belinsky SA, Leng S. Sex-specific association of sequence variants in CBS and MTRR with risk for promoter hypermethylation in the lung epithelium of smokers. Carcinogenesis. 33: 1542-7. PMID 22665368 DOI: 10.1093/Carcin/Bgs194 |
0.374 |
|
| 2012 |
Chen W, Xu X, Bai L, Padilla MT, Gott KM, Leng S, Tellez CS, Wilder JA, Belinsky SA, Scott BR, Lin Y. Low-dose gamma-irradiation inhibits IL-6 secretion from human lung fibroblasts that promotes bronchial epithelial cell transformation by cigarette-smoke carcinogen. Carcinogenesis. 33: 1368-74. PMID 22556270 DOI: 10.1093/carcin/bgs159 |
0.33 |
|
| 2012 |
Leng S, Do K, Yingling CM, Picchi MA, Wolf HJ, Kennedy TC, Feser WJ, Baron AE, Franklin WA, Brock MV, Herman JG, Baylin SB, Byers T, Stidley CA, Belinsky SA. Defining a gene promoter methylation signature in sputum for lung cancer risk assessment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 3387-95. PMID 22510351 DOI: 10.1158/1078-0432.Ccr-11-3049 |
0.431 |
|
| 2012 |
Tessema M, Yingling CM, Grimes MJ, Thomas CL, Liu Y, Leng S, Joste N, Belinsky SA. Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers. Plos One. 7: e34850. PMID 22496870 DOI: 10.1371/journal.pone.0034850 |
0.534 |
|
| 2012 |
Liu Y, Bernauer AM, Yingling CM, Belinsky SA. HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer. Carcinogenesis. 33: 1187-92. PMID 22467238 DOI: 10.1093/carcin/bgs142 |
0.416 |
|
| 2012 |
Xu X, Bai L, Chen W, Padilla MT, Liu Y, Kim KC, Belinsky SA, Lin Y. MUC1 contributes to BPDE-induced human bronchial epithelial cell transformation through facilitating EGFR activation. Plos One. 7: e33846. PMID 22457794 DOI: 10.1371/journal.pone.0033846 |
0.364 |
|
| 2012 |
Tessema M, Yingling CM, Thomas CL, Klinge DM, Bernauer AM, Liu Y, Dacic S, Siegfried JM, Dahlberg SE, Schiller JH, Belinsky SA. SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15. Oncogene. 31: 4107-16. PMID 22158045 DOI: 10.1038/Onc.2011.577 |
0.46 |
|
| 2012 |
Leng S, Stidley CA, Liu Y, Edlund CK, Willink RP, Han Y, Landi MT, Thun M, Picchi MA, Bruse SE, Crowell RE, Van Den Berg D, Caporaso NE, Amos CI, Siegfried JM, ... ... Belinsky SA, et al. Genetic determinants for promoter hypermethylation in the lungs of smokers: a candidate gene-based study. Cancer Research. 72: 707-15. PMID 22139380 DOI: 10.1158/0008-5472.Can-11-3194 |
0.457 |
|
| 2012 |
Bauman J, Verschraegen C, Belinsky S, Muller C, Rutledge T, Fekrazad M, Ravindranathan M, Lee SJ, Jones D. A phase I study of 5-azacytidine and erlotinib in advanced solid tumor malignancies. Cancer Chemotherapy and Pharmacology. 69: 547-54. PMID 21901396 DOI: 10.1007/S00280-011-1729-2 |
0.355 |
|
| 2012 |
Wang TW, Campbell JD, Luo L, Liu G, Xiao J, Lenburg ME, Belinsky SA, Spira A. Deep sequencing of the microRNA transcriptome in current, former, and never smokers with lung adenocarcinoma Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S6-P38 |
0.385 |
|
| 2012 |
Tessema M, Yingling CM, Grimes MJ, Thomas CL, Liu Y, Leng S, Joste N, Belinsky S. Abstract 3147: Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers Cancer Research. 72: 3147-3147. DOI: 10.1158/1538-7445.Am2012-3147 |
0.482 |
|
| 2011 |
Juergens RA, Wrangle J, Vendetti FP, Murphy SC, Zhao M, Coleman B, Sebree R, Rodgers K, Hooker CM, Franco N, Lee B, Tsai S, Delgado IE, Rudek MA, Belinsky SA, et al. Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. Cancer Discovery. 1: 598-607. PMID 22586682 DOI: 10.1158/2159-8290.Cd-11-0214 |
0.341 |
|
| 2011 |
Leng S, Bernauer AM, Zhai R, Tellez CS, Su L, Burki EA, Picchi MA, Stidley CA, Crowell RE, Christiani DC, Belinsky SA. Discovery of common SNPs in the miR-205/200 family-regulated epithelial to mesenchymal transition pathway and their association with risk for non-small cell lung cancer. International Journal of Molecular Epidemiology and Genetics. 2: 145-55. PMID 21686129 |
0.309 |
|
| 2011 |
Tellez CS, Juri DE, Do K, Bernauer AM, Thomas CL, Damiani LA, Tessema M, Leng S, Belinsky SA. EMT and stem cell-like properties associated with miR-205 and miR-200 epigenetic silencing are early manifestations during carcinogen-induced transformation of human lung epithelial cells. Cancer Research. 71: 3087-97. PMID 21363915 DOI: 10.1158/0008-5472.Can-10-3035 |
0.759 |
|
| 2011 |
Leng S, Bernauer AM, Hong C, Do KC, Yingling CM, Flores KG, Tessema M, Tellez CS, Willink RP, Burki EA, Picchi MA, Stidley CA, Prados MD, Costello JF, Gilliland FD, ... ... Belinsky SA, et al. The A/G allele of rs16906252 predicts for MGMT methylation and is selectively silenced in premalignant lesions from smokers and in lung adenocarcinomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 2014-23. PMID 21355081 DOI: 10.1158/1078-0432.Ccr-10-3026 |
0.398 |
|
| 2011 |
Belinsky SA, Grimes MJ, Picchi MA, Mitchell HD, Stidley CA, Tesfaigzi Y, Channell MM, Liu Y, Casero RA, Baylin SB, Reed MD, Tellez CS, March TH. Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model. Cancer Research. 71: 454-62. PMID 21224363 DOI: 10.1158/0008-5472.Can-10-3184 |
0.472 |
|
| 2011 |
Juergens R, Vendetti F, Wrangle J, Coleman B, Sebree R, Rudek-Renaut M, Belinsky S, Brock M, Herman J, Baylin S, Rudin C. Abstract LB-411: A phase II study of combination epigenetic therapy in advanced non-small cell lung cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-411 |
0.403 |
|
| 2011 |
Brock MV, Juergens RA, Wrangle J, Vendetti FP, Murphy S, Zhao M, Coleman B, Sebree R, Rodgers K, Hooker CM, Franco N, Lee B, Tsai S, Delgado IE, Rudek MA, ... Belinsky S, et al. Abstract ED03-04: Using epigenetic biomarkers as prognostic and predictive markers in non-small cell lung cancer (NSCLC) and the promise of epigenetic therapy Cancer Epidemiology, Biomarkers & Prevention. 20. DOI: 10.1158/1055-9965.Disp-11-Ed03-04 |
0.528 |
|
| 2011 |
Leng S, Bernauer AM, Zhai R, Tellez CS, Su L, Burki EA, Picchi MA, Stidley CA, Crowell RE, Christiani DC, Belinsky SA. Discovery of common SNPs in the miR-205/200 familyregulatedepithelial to mesenchymal transition pathway and their association with risk for non-small cell lung cancer International Journal of Molecular Epidemiology and Genetics. 2: 145-155. |
0.309 |
|
| 2010 |
Tessema M, Klinge DM, Yingling CM, Do K, Van Neste L, Belinsky SA. Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis Oncogene. 29: 5159-5170. PMID 20562917 DOI: 10.1038/onc.2010.255 |
0.544 |
|
| 2010 |
Varella-Garcia M, Schulte AP, Wolf HJ, Feser WJ, Zeng C, Braudrick S, Yin X, Hirsch FR, Kennedy TC, Keith RL, Barón AE, Belinsky SA, Miller YE, Byers T, Franklin WA. The detection of chromosomal aneusomy by fluorescence in situ hybridization in sputum predicts lung cancer incidence. Cancer Prevention Research (Philadelphia, Pa.). 3: 447-53. PMID 20332298 DOI: 10.1158/1940-6207.Capr-09-0165 |
0.334 |
|
| 2010 |
Stidley CA, Picchi MA, Leng S, Willink R, Crowell RE, Flores KG, Kang H, Byers T, Gilliland FD, Belinsky SA. Multivitamins, folate, and green vegetables protect against gene promoter methylation in the aerodigestive tract of smokers. Cancer Research. 70: 568-74. PMID 20068159 DOI: 10.1158/0008-5472.Can-09-3410 |
0.489 |
|
| 2010 |
Murray-Stewart T, Belinsky S, Marton L, Casero RA. Abstract LB-97: Combination of a conformationally restricted polyamine analogue with DNA methyltransferase or histone deacetylase inhibition induces synergistic reexpression of aberrantly silenced tumor suppressor genes Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-97 |
0.514 |
|
| 2009 |
Juergens RA, Vendetti F, Coleman B, Sebree RS, Rudek MA, Belinsky S, Brock M, Herman J, Baylin S, Rudin CM. Interim analysis of a phase II trial of 5-azacitidine (5AC) and entinostat (SNDX-275) in relapsed advanced lung cancer (NSCLC). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 8055. PMID 27962870 DOI: 10.1200/Jco.2009.27.15_Suppl.8055 |
0.518 |
|
| 2009 |
Pulling LC, Grimes MJ, Damiani LA, Juri DE, Do K, Tellez CS, Belinsky SA. Dual promoter regulation of death-associated protein kinase gene leads to differentially silenced transcripts by methylation in cancer. Carcinogenesis. 30: 2023-30. PMID 19917631 DOI: 10.1093/Carcin/Bgp276 |
0.711 |
|
| 2009 |
Lyon CM, Klinge DM, Do KC, Grimes MJ, Thomas CL, Damiani LA, March TH, Stidley CA, Belinsky SA. Rosiglitazone prevents the progression of preinvasive lung cancer in a murine model. Carcinogenesis. 30: 2095-9. PMID 19861651 DOI: 10.1093/Carcin/Bgp260 |
0.775 |
|
| 2009 |
Scott BR, Belinsky SA, Leng S, Lin Y, Wilder JA, Damiani LA. Radiation-stimulated epigenetic reprogramming of adaptive-response genes in the lung: an evolutionary gift for mounting adaptive protection against lung cancer. Dose-Response : a Publication of International Hormesis Society. 7: 104-31. PMID 19543479 DOI: 10.2203/Dose-Response.08-016.Scott |
0.778 |
|
| 2009 |
Tessema M, Yu YY, Stidley CA, Machida EO, Schuebel KE, Baylin SB, Belinsky SA. Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers. Carcinogenesis. 30: 1132-8. PMID 19435948 DOI: 10.1093/Carcin/Bgp114 |
0.56 |
|
| 2008 |
Tessema M, Belinsky SA. Mining the epigenome for methylated genes in lung cancer. Proceedings of the American Thoracic Society. 5: 806-10. PMID 19017733 DOI: 10.1513/pats.200805-045TH |
0.516 |
|
| 2008 |
Damiani LA, Yingling CM, Leng S, Romo PE, Nakamura J, Belinsky SA. Carcinogen-induced gene promoter hypermethylation is mediated by DNMT1 and causal for transformation of immortalized bronchial epithelial cells. Cancer Research. 68: 9005-14. PMID 18974146 DOI: 10.1158/0008-5472.Can-08-1276 |
0.8 |
|
| 2008 |
Chin LJ, Ratner E, Leng S, Zhai R, Nallur S, Babar I, Muller RU, Straka E, Su L, Burki EA, Crowell RE, Patel R, Kulkarni T, Homer R, Zelterman D, ... ... Belinsky SA, et al. A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Research. 68: 8535-40. PMID 18922928 DOI: 10.1158/0008-5472.Can-08-2129 |
0.354 |
|
| 2008 |
Belinsky SA, Schiller JH, Stidley CA. DNA methylation biomarkers to assess therapy and chemoprevention for non-small cell lung cancer. Nutrition Reviews. 66: S24-6. PMID 18673483 DOI: 10.1111/j.1753-4887.2008.00061.x |
0.389 |
|
| 2008 |
Wakamatsu N, Collins JB, Parker JS, Tessema M, Clayton NP, Ton TV, Hong HH, Belinsky S, Devereux TR, Sills RC, Lahousse SA. Gene expression studies demonstrate that the K-ras/Erk MAP kinase signal transduction pathway and other novel pathways contribute to the pathogenesis of cumene-induced lung tumors. Toxicologic Pathology. 36: 743-52. PMID 18648096 DOI: 10.1177/0192623308320801 |
0.441 |
|
| 2008 |
Leng S, Stidley CA, Willink R, Bernauer A, Do K, Picchi MA, Sheng X, Frasco MA, Van Den Berg D, Gilliland FD, Zima C, Crowell RE, Belinsky SA. Double-strand break damage and associated DNA repair genes predispose smokers to gene methylation. Cancer Research. 68: 3049-56. PMID 18413776 DOI: 10.1158/0008-5472.Can-07-6344 |
0.446 |
|
| 2008 |
Tessema M, Willink R, Do K, Yu YY, Yu W, Machida EO, Brock M, Van Neste L, Stidley CA, Baylin SB, Belinsky SA. Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25. Cancer Research. 68: 1707-14. PMID 18339850 DOI: 10.1158/0008-5472.Can-07-6325 |
0.537 |
|
| 2008 |
Brock MV, Hooker CM, Ota-Machida E, Han Y, Guo M, Ames S, Glöckner S, Piantadosi S, Gabrielson E, Pridham G, Pelosky K, Belinsky SA, Yang SC, Baylin SB, Herman JG. DNA methylation markers and early recurrence in stage I lung cancer. The New England Journal of Medicine. 358: 1118-28. PMID 18337602 DOI: 10.1056/Nejmoa0706550 |
0.462 |
|
| 2008 |
Luxen S, Belinsky SA, Knaus UG. Silencing of DUOX NADPH oxidases by promoter hypermethylation in lung cancer. Cancer Research. 68: 1037-45. PMID 18281478 DOI: 10.1158/0008-5472.CAN-07-5782 |
0.507 |
|
| 2008 |
Juergens RA, Vendetti F, Coleman B, Sebree RS, Rudek MA, Belinsky SA, Brock MV, Herman JG, Baylin SB, Rudin CM. Phase I trial of 5-azacitidine (5AC) and SNDX-275 in advanced lung cancer (NSCLC) Journal of Clinical Oncology. 26: 19036-19036. DOI: 10.1200/Jco.2008.26.15_Suppl.19036 |
0.366 |
|
| 2007 |
Lyon CM, Klinge DM, Liechty KC, Gentry FD, March TH, Kang T, Gilliland FD, Adamova G, Rusinova G, Telnov V, Belinsky SA. Radiation-induced lung adenocarcinoma is associated with increased frequency of genes inactivated by promoter hypermethylation. Radiation Research. 168: 409-14. PMID 17903034 DOI: 10.1667/Rr0825.1 |
0.518 |
|
| 2007 |
Belinsky SA, Grimes MJ, Casas E, Stidley CA, Franklin WA, Bocklage TJ, Johnson DH, Schiller JH. Predicting gene promoter methylation in non-small-cell lung cancer by evaluating sputum and serum. British Journal of Cancer. 96: 1278-83. PMID 17406356 DOI: 10.1038/sj.bjc.6603721 |
0.45 |
|
| 2007 |
Liu H, Zhou Y, Boggs SE, Belinsky SA, Liu J. Cigarette smoke induces demethylation of prometastatic oncogene synuclein-γ in lung cancer cells by downregulation of DNMT3B Oncogene. 26: 5900-5910. PMID 17369845 DOI: 10.1038/sj.onc.1210400 |
0.442 |
|
| 2007 |
Franklin WA, Byers T, Wolf HJ, Braudich S, Hirsch FR, Miller YE, Keith RL, Kennedy TC, Belinsky S, Varella-Garcia M. FISHing for lung cancer: Promising findings using multi-targeted interphase fluorescence in situ hybridization (FISH) for lung cancer detection in sputum Journal of Clinical Oncology. 25: 7567-7567. DOI: 10.1200/Jco.2007.25.18_Suppl.7567 |
0.462 |
|
| 2007 |
Lyon CM, Belinsky SA, Klinge D, March T, Keith R, Stidley C. P2-137: Rosiglitazone prevents the progression of preinvasive lung cancer in a murine model Journal of Thoracic Oncology. 2: S545-S546. DOI: 10.1097/01.JTO.0000283601.08974.3f |
0.339 |
|
| 2006 |
Machida EO, Brock MV, Hooker CM, Nakayama J, Ishida A, Amano J, Picchi MA, Belinsky SA, Herman JG, Taniguchi S, Baylin SB. Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer. Cancer Research. 66: 6210-8. PMID 16778195 DOI: 10.1158/0008-5472.Can-05-4447 |
0.403 |
|
| 2006 |
Vuillemenot BR, Hutt JA, Belinsky SA. Gene promoter hypermethylation in mouse lung tumors. Molecular Cancer Research : McR. 4: 267-73. PMID 16603640 DOI: 10.1158/1541-7786.MCR-05-0218 |
0.579 |
|
| 2006 |
Belinsky SA, Liechty KC, Gentry FD, Wolf HJ, Rogers J, Vu K, Haney J, Kennedy TC, Hirsch FR, Miller Y, Franklin WA, Herman JG, Baylin SB, Bunn PA, Byers T. Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. Cancer Research. 66: 3338-44. PMID 16540689 DOI: 10.1158/0008-5472.Can-05-3408 |
0.47 |
|
| 2006 |
Belinsky SA, Grimes M, Johnson D, Levy D, Schiller J. Predicting gene promoter methylation in lung tumors through examination of sputum and serum Journal of Clinical Oncology. 24: 7208-7208. DOI: 10.1200/jco.2006.24.18_suppl.7208 |
0.494 |
|
| 2005 |
Belinsky SA, Klinge DM, Dekker JD, Smith MW, Bocklage TJ, Gilliland FD, Crowell RE, Karp DD, Stidley CA, Picchi MA. Gene promoter methylation in plasma and sputum increases with lung cancer risk. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 6505-11. PMID 16166426 DOI: 10.1158/1078-0432.Ccr-05-0625 |
0.426 |
|
| 2005 |
Hutt JA, Vuillemenot BR, Barr EB, Grimes MJ, Hahn FF, Hobbs CH, March TH, Gigliotti AP, Seilkop SK, Finch GL, Mauderly JL, Belinsky SA. Life-span inhalation exposure to mainstream cigarette smoke induces lung cancer in B6C3F1 mice through genetic and epigenetic pathways. Carcinogenesis. 26: 1999-2009. PMID 15944214 DOI: 10.1093/carcin/bgi150 |
0.402 |
|
| 2005 |
Belinsky SA. Silencing of genes by promoter hypermethylation: key event in rodent and human lung cancer. Carcinogenesis. 26: 1481-7. PMID 15661809 DOI: 10.1093/carcin/bgi020 |
0.522 |
|
| 2005 |
Divine KK, Pulling LC, Marron-Terada PG, Liechty KC, Kang T, Schwartz AG, Bocklage TJ, Coons TA, Gilliland FD, Belinsky SA. Multiplicity of abnormal promoter methylation in lung adenocarcinomas from smokers and never smokers. International Journal of Cancer. 114: 400-5. PMID 15578700 DOI: 10.1002/Ijc.20761 |
0.794 |
|
| 2004 |
Belinsky SA. Gene-promoter hypermethylation as a biomarker in lung cancer. Nature Reviews. Cancer. 4: 707-17. PMID 15343277 DOI: 10.1038/nrc1432 |
0.451 |
|
| 2004 |
Mauderly JL, Gigliotti AP, Barr EB, Bechtold WE, Belinsky SA, Hahn FF, Hobbs CA, March TH, Seilkop SK, Finch GL. Chronic inhalation exposure to mainstream cigarette smoke increases lung and nasal tumor incidence in rats. Toxicological Sciences : An Official Journal of the Society of Toxicology. 81: 280-92. PMID 15213336 DOI: 10.1093/toxsci/kfh203 |
0.354 |
|
| 2004 |
Pulling LC, Vuillemenot BR, Hutt JA, Devereux TR, Belinsky SA. Aberrant promoter hypermethylation of the death-associated protein kinase gene is early and frequent in murine lung tumors induced by cigarette smoke and tobacco carcinogens. Cancer Research. 64: 3844-8. PMID 15172992 DOI: 10.1158/0008-5472.Can-03-2119 |
0.81 |
|
| 2004 |
Douglas DB, Akiyama Y, Carraway H, Belinsky SA, Esteller M, Gabrielson E, Weitzman S, Williams T, Herman JG, Baylin SB. Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer. Cancer Research. 64: 1611-20. PMID 14996719 DOI: 10.1158/0008-5472.Can-0318-2 |
0.316 |
|
| 2004 |
Belinsky SA, Klinge DM, Liechty KC, March TH, Kang T, Gilliland FD, Sotnic N, Adamova G, Rusinova G, Telnov V. Plutonium targets the p16 gene for inactivation by promoter hypermethylation in human lung adenocarcinoma. Carcinogenesis. 25: 1063-7. PMID 14742312 DOI: 10.1093/Carcin/Bgh096 |
0.459 |
|
| 2004 |
Vuillemenot BR, Pulling LC, Palmisano WA, Hutt JA, Belinsky SA. Carcinogen exposure differentially modulates RAR-beta promoter hypermethylation, an early and frequent event in mouse lung carcinogenesis. Carcinogenesis. 25: 623-9. PMID 14656941 DOI: 10.1093/Carcin/Bgh038 |
0.801 |
|
| 2003 |
Belinsky SA, Klinge DM, Stidley CA, Issa JP, Herman JG, March TH, Baylin SB. Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer. Cancer Research. 63: 7089-93. PMID 14612500 |
0.511 |
|
| 2003 |
Pulling LC, Divine KK, Klinge DM, Gilliland FD, Kang T, Schwartz AG, Bocklage TJ, Belinsky SA. Promoter hypermethylation of the O6-methylguanine-DNA methyltransferase gene: more common in lung adenocarcinomas from never-smokers than smokers and associated with tumor progression. Cancer Research. 63: 4842-8. PMID 12941804 |
0.787 |
|
| 2003 |
Palmisano WA, Crume KP, Grimes MJ, Winters SA, Toyota M, Esteller M, Joste N, Baylin SB, Belinsky SA. Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers. Cancer Research. 63: 4620-5. PMID 12907641 |
0.467 |
|
| 2003 |
West KA, Brognard J, Clark AS, Linnoila IR, Yang X, Swain SM, Harris C, Belinsky S, Dennis PA. Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. The Journal of Clinical Investigation. 111: 81-90. PMID 12511591 DOI: 10.1172/Jci16147 |
0.418 |
|
| 2003 |
West KA, Linnoila IR, Brognard J, Belinsky S, Harris CC, Dennis PA. P-326 Tobacco carcinogen-induced cellular transformation increases Akt activation in vitro and in vivo Lung Cancer. 41. DOI: 10.1016/S0169-5002(03)92294-X |
0.318 |
|
| 2002 |
Wardlaw SA, Zhang N, Belinsky SA. Transcriptional regulation of basal cyclooxygenase-2 expression in murine lung tumor-derived cell lines by CCAAT/enhancer-binding protein and activating transcription factor/cAMP response element-binding protein. Molecular Pharmacology. 62: 326-33. PMID 12130685 DOI: 10.1124/mol.62.2.326 |
0.35 |
|
| 2002 |
Belinsky SA, Palmisano WA, Gilliland FD, Crooks LA, Divine KK, Winters SA, Grimes MJ, Harms HJ, Tellez CS, Smith TM, Moots PP, Lechner JF, Stidley CA, Crowell RE. Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers. Cancer Research. 62: 2370-7. PMID 11956099 |
0.531 |
|
| 2002 |
Gilliland FD, Harms HJ, Crowell RE, Li YF, Willink R, Belinsky SA. Glutathione S-transferase P1 and NADPH quinone oxidoreductase polymorphisms are associated with aberrant promoter methylation of P16(INK4a) and O(6)-methylguanine-DNA methyltransferase in sputum. Cancer Research. 62: 2248-52. PMID 11956078 |
0.448 |
|
| 2002 |
Cohen AJ, Belinsky S, Franklin W, Beard S. Molecular and physiologic evidence for 5'CpG island methylation of the endothelin B receptor gene in lung cancer. Chest. 121: 27S-28S. PMID 11893663 DOI: 10.1378/Chest.121.3_Suppl.27S-A |
0.515 |
|
| 2002 |
Belinsky SA, Snow SS, Nikula KJ, Finch GL, Tellez CS, Palmisano WA. Aberrant CpG island methylation of the p16(INK4a) and estrogen receptor genes in rat lung tumors induced by particulate carcinogens. Carcinogenesis. 23: 335-9. PMID 11872642 |
0.5 |
|
| 2002 |
Belinsky SA, Divine KK, Esteller M, Baylin SB, Herman JG, Palmisano WA. Aberrant promoter methylation in sputum and serum for lung cancer detection Journal of Clinical Ligand Assay. 25: 95-99. |
0.47 |
|
| 2001 |
Auckley DH, Crowell RE, Heaphy ER, Stidley CA, Lechner JF, Gilliland FD, Belinsky SA. Reduced DNA-dependent protein kinase activity is associated with lung cancer Carcinogenesis. 22: 723-727. PMID 11323390 DOI: 10.1093/Carcin/22.5.723 |
0.331 |
|
| 2001 |
Pulling LC, Klinge DM, Belinsky SA. p16INK4a and beta-catenin alterations in rat liver tumors induced by NNK. Carcinogenesis. 22: 461-6. PMID 11238187 DOI: 10.1093/Carcin/22.3.461 |
0.762 |
|
| 2001 |
Lechner JF, Fugaro JM, Wong Y, Pass HI, Harris CC, Belinsky SA. Perspective: Cell differentiation theory may advance early detection of and therapy for lung cancer Radiation Research. 155: 235-238. PMID 11121240 |
0.373 |
|
| 2001 |
Divine KK, Gilliland FD, Crowell RE, Stidley CA, Bocklage TJ, Cook DL, Belinsky SA. The XRCC1 399 glutamine allele is a risk factor for adenocarcinoma of the lung. Mutation Research. 461: 273-8. PMID 11104903 DOI: 10.1016/S0921-8777(00)00059-8 |
0.314 |
|
| 2001 |
March TH, Marron-Terada PG, Belinsky SA. Refinement of an orthotopic lung cancer model in the nude rat Veterinary Pathology. 38: 483-490. DOI: 10.1354/vp.38-5-483 |
0.421 |
|
| 2000 |
Palmisano WA, Divine KK, Saccomanno G, Gilliland FD, Baylin SB, Herman JG, Belinsky SA. Predicting lung cancer by detecting aberrant promoter methylation in sputum Cancer Research. 60: 5954-5958. PMID 11085511 |
0.445 |
|
| 2000 |
Baylin SB, Belinsky SA, Herman JG. Aberrant methylation of gene promoters in cancer - Concepts, misconcepts, and promise Journal of the National Cancer Institute. 92: 1460-1461. PMID 10995795 DOI: 10.1093/Jnci/92.18.1460 |
0.486 |
|
| 2000 |
Wardlaw SA, March TH, Belinsky SA. Cyclooxygenase-2 expression is abundant in alveolar type II cells in lung cancer-sensitive mouse strains and in premalignant lesions Carcinogenesis. 21: 1371-1377. PMID 10874016 |
0.424 |
|
| 1999 |
Nuovo GJ, Plaia TW, Belinsky SA, Baylin SB, Herman JG. In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis Proceedings of the National Academy of Sciences of the United States of America. 96: 12754-12759. PMID 10535995 DOI: 10.1073/Pnas.96.22.12754 |
0.406 |
|
| 1998 |
Neft RE, Crowell RE, Gilliland FD, Murphy MM, Lane JL, Harms H, Coons T, Heaphy E, Belinsky SA, Lechner JF. Frequency of trisomy 20 in nonmalignant bronchial epithelium from lung cancer patients and cancer-free former uranium miners and smokers Cancer Epidemiology Biomarkers and Prevention. 7: 1051-1054. PMID 9829716 |
0.36 |
|
| 1998 |
Belinsky SA, Nikula KJ, Palmisano WA, Michels R, Saccomanno G, Gabrielson E, Baylin SB, Herman JG. Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis Proceedings of the National Academy of Sciences of the United States of America. 95: 11891-11896. PMID 9751761 DOI: 10.1073/Pnas.95.20.11891 |
0.478 |
|
| 1998 |
Jones-Bolin SE, Johansson E, Palmisano WA, Anderson MW, Wiest JS, Belinsky SA. Effect of promoter and intron 2 polymorphisms on murine lung K-ras gene expression Carcinogenesis. 19: 1503-1508. PMID 9744549 DOI: 10.1093/carcin/19.8.1503 |
0.394 |
|
| 1998 |
Belinsky SA. Role of the cytosine DNA-methyltransferase and p16(INK4a) genes in the development of mouse lung tumors Experimental Lung Research. 24: 463-479. PMID 9659578 |
0.507 |
|
| 1998 |
Kennedy CH, Cueto R, Belinsky SA, Lechner JF, Pryor WA. Overexpression of hMTH1 mRNA: a molecular marker of oxidative stress in lung cancer cells. Febs Letters. 429: 17-20. PMID 9657375 DOI: 10.1016/S0014-5793(98)00505-5 |
0.319 |
|
| 1998 |
Lechner JF, Neft RE, Gilliland FD, Crowell RE, Auckley DH, Temes RT, Belinsky SA. Individuals at high risk for lung cancer have airway epithelial cells with chromosome aberrations frequently found in lung tumor cells In Vivo. 12: 23-26. PMID 9575422 |
0.383 |
|
| 1997 |
Crowell RE, Belinsky SA. Genetic changes in lung cancer: Potential biomarkers for early detection and prevention Journal of Laboratory and Clinical Medicine. 130: 550-557. PMID 9422328 |
0.367 |
|
| 1997 |
Lechner JF, Neft RE, Gilliland FD, Crowell RE, Belinsky SA. Molecular identification of individuals at high risk for lung cancer Radiation Oncology Investigations. 5: 103-105. PMID 9303064 DOI: 10.1002/(SICI)1520-6823(1997)5:3<103::AID-ROI3>3.0.CO;2-1 |
0.305 |
|
| 1997 |
Belinsky SA, Swafford DS, Finch GL, Mitchell CE, Kelly G, Hahn FF, Anderson MW, Nikula KJ. Alterations in the K-ras and p53 genes in rat lung tumors. Environmental Health Perspectives. 105: 901-6. PMID 9255578 |
0.419 |
|
| 1997 |
Belinsky SA, Swafford DS, Middleton SK, Kennedy CH, Tesfaigzi J. Deletion and differential expression of p16INK4a in mouse lung tumors. Carcinogenesis. 18: 115-20. PMID 9054597 DOI: 10.1093/carcin/18.1.115 |
0.391 |
|
| 1997 |
Swafford DS, Middleton SK, Palmisano WA, Nikula KJ, Tesfaigzi J, Baylin SB, Herman JG, Belinsky SA. Frequent aberrant methylation of p16INK4a in primary rat lung tumors. Molecular and Cellular Biology. 17: 1366-74. PMID 9032263 DOI: 10.1128/Mcb.17.3.1366 |
0.491 |
|
| 1997 |
Tierney LA, Neft RE, Belinsky SA, Lauer FT, Gilliland FD, Crowell RE, Lechner JF. Double-label suspension immunohistochemistry for the detection of gene dysfunction in sputum Journal of Histotechnology. 20: 13-17. DOI: 10.1179/His.1997.20.1.13 |
0.302 |
|
| 1997 |
Belinsky S, Crowell R, Neft R, Gilliland F, Lechner J. 728 Loss of chromosome 9q21-23 in nonmalignant bronchial epithelial cells from individuals at risk for lung cancer Lung Cancer. 18: 187. DOI: 10.1016/S0169-5002(97)80108-0 |
0.366 |
|
| 1996 |
Finch GL, Hoover MD, Hahn FF, Nikula KJ, Belinsky SA, Haley PJ, Griffith WC. Animal models of beryllium-induced lung disease. Environmental Health Perspectives. 104: 973-9. PMID 8933044 |
0.36 |
|
| 1996 |
Issa JPJ, Baylin SB, Belinsky SA. Methylation of the estrogen receptor CpG island in lung tumors is related to the specific type of carcinogen exposure Cancer Research. 56: 3655-3658. PMID 8706002 |
0.531 |
|
| 1996 |
Belinsky SA, Nikula KJ, Baylin SB, Issa JPJ. Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer Proceedings of the National Academy of Sciences of the United States of America. 93: 4045-4050. PMID 8633014 DOI: 10.1073/Pnas.93.9.4045 |
0.372 |
|
| 1996 |
Finch GL, Nikula KJ, Belinsky SA, Barr EB, Stoner GD, Lechner JF. Failure of cigarette smoke to induce or promote lung cancer in the A/J mouse Cancer Letters. 99: 161-167. PMID 8616820 DOI: 10.1016/0304-3835(95)04059-5 |
0.372 |
|
| 1996 |
Belinsky SA, Middleton SK, Picksley SM, Hahn FF, Nikula KJ. Analysis of the K-ras and p53 pathways in X-ray-induced lung tumors in the rat Radiation Research. 145: 449-456. PMID 8600505 DOI: 10.2307/3579066 |
0.356 |
|
| 1995 |
Belinsky SA, Nikula KJ, Baylin SB, Issa Jp. A microassay for measuring cytosine DNA methyltransferase activity during tumor progression Toxicology Letters. 82: 335-340. PMID 8597074 DOI: 10.1016/0378-4274(95)03486-2 |
0.366 |
|
| 1995 |
Shivapurkar N, Belinsky SA, Wolf DC, Tang Z, Alabaster O. Absence of p53 gene mutations in rat colon carcinomas induced by azoxymethane Cancer Letters. 96: 63-70. PMID 7553609 DOI: 10.1016/0304-3835(95)03947-U |
0.328 |
|
| 1995 |
Swafford DS, Nikula KJ, Mitchell CE, Belinsky SA. Low frequency of alterations in p53, K-ras, and mdm2 in rat lung neoplasms induced by diesel exhaust or carbon black. Carcinogenesis. 16: 1215-21. PMID 7539340 DOI: 10.1093/carcin/16.5.1215 |
0.32 |
|
| 1994 |
Nickell-Brady C, Hahn FF, Finch GL, Belinsky SA. Analysis of K-ras, p53 and c-raf-1 mutations in beryllium-induced rat lung tumors. Carcinogenesis. 15: 257-62. PMID 7545909 DOI: 10.1093/carcin/15.2.257 |
0.409 |
|
| 1993 |
Belinsky SA, Stefanski SA, Anderson2 MW. The A/J Mouse Lung as a Model for Developing New Chemointervention Strategies Cancer Research. 53: 410-416. PMID 8417832 |
0.348 |
|
| 1993 |
Devereux TR, Belinsky SA, Maronpot RR, White CM, Hegi ME, Patel AC, Foley JF, Greenwell A, Anderson MW. Comparison of pulmonary O6-methylguanine DNA adduct levels and Ki-ras activation in lung tumors from resistant and susceptible mouse strains. Molecular Carcinogenesis. 8: 177-85. PMID 8216736 DOI: 10.1002/mc.2940080308 |
0.362 |
|
| 1991 |
Belinsky SA, Devereux TR, White CM, Foley JF, Maronpot RR, Anderson MW. Role of clara cells and type II cells in the development of pulmonary tumors in rats and mice following exposure to a tobacco-specific nitrosamine Experimental Lung Research. 17: 263-278. PMID 2050030 DOI: 10.3109/01902149109064417 |
0.371 |
|
| 1991 |
Devereux TR, Anderson MW, Belinsky SA. Role of ras protooncogene activation in the formation of spontaneous and nitrosamine-induced lung tumors in the resistant c3h mouse Carcinogenesis. 12: 299-303. PMID 1995195 DOI: 10.1093/Carcin/12.2.299 |
0.433 |
|
| 1990 |
Belinsky SA, Foley JF, White CM, Anderson MW, Maronpot RR. Dose-Response Relationship between O6-Methylguanine Formation in Clara Cells and Induction of Pulmonary Neoplasia in the Rat by 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Cancer Research. 50: 3772-3780. PMID 2340522 |
0.35 |
|
| 1990 |
Belinsky SA, Devereux TR, Anderson MW. Role of DNA methylation in the activation of proto-oncogenes and the induction of pulmonary neoplasia by nitrosamines Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 233: 105-116. PMID 2233792 DOI: 10.1016/0027-5107(90)90155-W |
0.439 |
|
| 1989 |
Belinsky SA, Devereux TR, Anderson MW, Maronpot RR, Stoner GD. Relationship between the Formation of Promutagenic Adducts and the Activation of the K-ras Protooncogene in Lung Tumors from A/J Mice Treated with Nitrosamines Cancer Research. 49: 5305-5311. PMID 2670201 |
0.415 |
|
| 1988 |
Devereux TR, Anderson MW, Belinsky SA. Factors Regulating Activation and DNA Alkylation by 4-(N-Methyl-N-nitrosamino)- 1 -(3-pyridyl)-l -butanone and Nitrosodimethylamine in Rat Lung and Isolated Lung Cells, and the Relationship to Carcinogenicity Cancer Research. 48: 4215-4221. PMID 3390815 |
0.345 |
|
| 1987 |
Belinsky SA, White CM, Devereux TR, Swenberg JA, Anderson MW. Cell selective alkylation of DNA in rat lung following low dose exposure to the tobacco specific carcinogen 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone. Cancer Research. 47: 1143-8. PMID 3802095 |
0.333 |
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