Eitan Amir, Ph.D. - Publications

Affiliations: 
2012 Health Policy, Management and Evaluation University of Toronto, Toronto, ON, Canada 
Area:
Health Care Management, Oncology

319 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kappel C, Elliott MJ, Kumar V, Nadler MB, Desnoyers A, Amir E. Comparative overall survival of CDK4/6 inhibitors in combination with endocrine therapy in advanced breast cancer. Scientific Reports. 14: 3129. PMID 38326452 DOI: 10.1038/s41598-024-53151-8  0.323
2024 Mittal A, Tamimi F, Molto C, Di Iorio M, Amir E. Benefit of adjuvant bisphosphonates in early breast cancer treated with contemporary systemic therapy: A meta-analysis of randomized control trials. Heliyon. 10: e24793. PMID 38312616 DOI: 10.1016/j.heliyon.2024.e24793  0.337
2023 Shachar SS, Korzets Y, Shepshelovich D, Zlothover N, Amir E, Tibau A, Goldvaser H. Reporting of post-protocol therapies in metastatic breast cancer registration clinical trials: A systematic review. Cancer Treatment Reviews. 122: 102666. PMID 38064877 DOI: 10.1016/j.ctrv.2023.102666  0.34
2023 Molto Valiente C, Amir E. Combining PARP inhibitors and platinum-based chemotherapy in metastatic triple negative and/or BRCA-associated breast cancer. Translational Cancer Research. 12: 1887-1890. PMID 37588734 DOI: 10.21037/tcr-23-365  0.313
2022 Mittal A, Tamimi F, Molto C, Meti N, Al-Showbaki L, Wilson BE, Amir E. Three-year Disease-free Survival in Randomized Trials of Neoadjuvant Chemotherapy and HER2-targeted therapy in Breast Cancer: A meta-analysis. Critical Reviews in Oncology/Hematology. 103880. PMID 36435297 DOI: 10.1016/j.critrevonc.2022.103880  0.326
2021 Saleh RR, Nadler MB, Desnoyers A, Meti N, Fazelzad R, Amir E. Platinum-based chemotherapy in early-stage triple negative breast cancer: A meta-analysis. Cancer Treatment Reviews. 100: 102283. PMID 34530283 DOI: 10.1016/j.ctrv.2021.102283  0.302
2021 Ethier JL, Desautels D, Robinson A, Amir E, Kong W, Booth CM. Practice Patterns and Outcomes of Novel Targeted Agents for the Treatment of ERBB2-Positive Metastatic Breast Cancer. Jama Oncology. PMID 34236387 DOI: 10.1001/jamaoncol.2021.2140  0.332
2021 Desnoyers A, Amir E, Tannock IF. Adjuvant Zoledronate Therapy for Women With Breast Cancer-Effective Treatment or Fool's Gold? Jama Oncology. PMID 34165515 DOI: 10.1001/jamaoncol.2021.1516  0.479
2021 Reinhorn D, Mutai R, Yerushalmi R, Moore A, Amir E, Goldvaser H. Locoregional therapy in de novo metastatic breast cancer: Systemic review and meta-analysis. Breast (Edinburgh, Scotland). 58: 173-181. PMID 34158167 DOI: 10.1016/j.breast.2021.05.003  0.315
2021 Ethier JL, Anderson GM, Austin PC, Clemons M, Parulekar W, Shepherd L, Trasiewicz LS, Tu D, Amir E. Influence of the competing risk of death on estimates of disease recurrence in trials of adjuvant endocrine therapy for early-stage breast cancer: A secondary analysis of MA.27, MA.17 and MA.17R. European Journal of Cancer (Oxford, England : 1990). 149: 117-127. PMID 33853037 DOI: 10.1016/j.ejca.2021.02.034  0.309
2021 Amir E, Cescon DW. Pembrolizumab monotherapy in metastatic triple-negative breast cancer. The Lancet. Oncology. PMID 33676605 DOI: 10.1016/S1470-2045(21)00019-X  0.301
2021 Desnoyers A, Wilson BE, Nadler MB, Amir E. Fragility index of trials supporting approval of anti-cancer drugs in common solid tumours. Cancer Treatment Reviews. 94: 102167. PMID 33652263 DOI: 10.1200/Jco.2020.38.15_Suppl.2055  0.381
2020 Saleh RR, Meti N, Ribnikar D, Goldvaser H, Ocana A, Templeton AJ, Seruga B, Amir E. Associations between safety, tolerability, and toxicity and the reporting of health-related quality of life in phase III randomized trials in common solid tumors. Cancer Medicine. PMID 32886422 DOI: 10.1002/Cam4.3390  0.333
2020 Desnoyers A, Nadler MB, Kumar V, Saleh R, Amir E. Comparison of treatment-related adverse events of different Cyclin-dependent kinase 4/6 inhibitors in metastatic breast cancer: A network meta-analysis. Cancer Treatment Reviews. 90: 102086. PMID 32861975 DOI: 10.1016/J.Ctrv.2020.102086  0.431
2020 McNamara MG, Jacobs T, Lamarca A, Hubner RA, Valle JW, Amir E. Impact of high tumor mutational burden in solid tumors and challenges for biomarker application. Cancer Treatment Reviews. 89: 102084. PMID 32738738 DOI: 10.1016/J.Ctrv.2020.102084  0.315
2020 Molto C, Hwang TJ, Borrell M, Andres M, Gich I, Barnadas A, Amir E, Kesselheim AS, Tibau A. Clinical benefit and cost of breakthrough cancer drugs approved by the US Food and Drug Administration. Cancer. PMID 32697362 DOI: 10.1002/Cncr.33095  0.365
2020 Reinhorn D, Yerushalmi R, Moore A, Desnoyers A, Saleh RR, Amir E, Goldvaser H. Evolution in the risk of adverse events of adjuvant endocrine therapy in postmenopausal women with early-stage breast cancer. Breast Cancer Research and Treatment. 182: 259-266. PMID 32488391 DOI: 10.1007/S10549-020-05715-1  0.414
2020 Keilty D, Namini SN, Swain M, Maganti M, Cil TD, McCready DR, Cescon DW, Amir E, Fleming R, Mulligan AM, Fyles A, Croke JM, Liu FF, Levin W, Koch CA, et al. Patterns of recurrence and predictors of survival in breast cancer patients treated with neoadjuvant chemotherapy, surgery, and radiation. International Journal of Radiation Oncology, Biology, Physics. PMID 32407932 DOI: 10.1016/J.Ijrobp.2020.04.044  0.397
2020 Templeton AJ, Amir E, Tannock IF. Informative censoring - a neglected cause of bias in oncology trials. Nature Reviews. Clinical Oncology. PMID 32273582 DOI: 10.1038/S41571-020-0368-0  0.489
2020 Lambert J, Lamacie M, Thampinathan B, Altaha MA, Esmaeilzadeh M, Nolan M, Fresno CU, Somerset E, Amir E, Marwick TH, Wintersperger BJ, Thavendiranathan P. Variability in echocardiography and MRI for detection of cancer therapy cardiotoxicity. Heart (British Cardiac Society). PMID 32098808 DOI: 10.1136/Heartjnl-2019-316297  0.304
2020 Calvillo-Argüelles O, Abdel-Qadir H, Suntheralingam S, Michalowska M, Amir E, Thavendiranathan P. Trastuzumab-Related Cardiotoxicity and Cardiac Care in Patients With HER2 Positive Metastatic Breast Cancer. The American Journal of Cardiology. PMID 32087998 DOI: 10.1016/J.Amjcard.2020.01.029  0.408
2020 Ocaña A, Amir E, Pandiella A. HER2 heterogeneity and resistance to anti-HER2 antibody-drug conjugates. Breast Cancer Research : Bcr. 22: 15. PMID 32005279 DOI: 10.1186/S13058-020-1252-7  0.356
2020 Saleh R, Bedard PL, Nguyen P, Malone ER, Yu C, Amir E, Earle C, Gyawali B, Hansen AR, Mittmann N, Peng Y, Pugh TJ, Abdul Razak AR, Sabatini P, Spreafico A, et al. An evaluation of administrative data linkage for measurement of real-world outcomes of large clinical panel sequencing for advanced solid tumors. Journal of Clinical Oncology. 38: e19303-e19303. DOI: 10.1200/Jco.2020.38.15_Suppl.E19303  0.374
2020 Almugbel F, Al-Showbaki L, Nadler M, Desnoyers A, Saleh R, Amir E. Macrocytosis as a predictor of response to capecitabine in solid cancers: A meta-analysis. Journal of Clinical Oncology. 38. DOI: 10.1200/Jco.2020.38.15_Suppl.E13080  0.411
2020 Desnoyers A, Nadler M, Kumar V, Saleh R, Amir E. Comparison of treatment-related adverse events (TRAE) of different CDK4/6 inhibitors (CDK4/6i) in metastatic breast cancer (MBC): A network meta-analysis. Journal of Clinical Oncology. 38. DOI: 10.1200/Jco.2020.38.15_Suppl.E13052  0.385
2020 Rodríguez AB, Molto C, Hwang TJ, Vokinger KN, Tapia JC, Saladich IJG, Templeton AJ, Barnadas A, Amir E, Tibau A. Factors associated with change in the magnitude of clinical benefit of anti-cancer drugs in the post-marketing period. Journal of Clinical Oncology. 38: 7052-7052. DOI: 10.1200/Jco.2020.38.15_Suppl.7052  0.357
2020 Nadler M, Desnoyers A, Saleh R, Amir E. Post-hoc power of clinical trials supporting anticancer drug approval by FDA. Journal of Clinical Oncology. 38: 2018-2018. DOI: 10.1200/Jco.2020.38.15_Suppl.2018  0.334
2020 Desnoyers A, Nadler MB, Saleh R, Amir E. Abstract P4-15-01: Fragility index of trials supporting approval of breast cancer drugs Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P4-15-01  0.435
2020 Saleh R, Nadler MB, Desnoyers A, Fazelzad R, Amir E. Abstract P4-14-09: Platinum-based chemotherapy in early-stage triple negative breast cancer: A meta-analysis Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P4-14-09  0.411
2020 Almugbel FA, Saleh R, Ocana A, Pandiella A, Amir E. Abstract P4-10-11: PIK3CA status as a predictor of benefit from drugs targeting the PI3K/AKT/mTOR pathway: A meta-analysis of randomized trials Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P4-10-11  0.32
2020 Tai F, Croxford R, Austin P, Amir E, Argüelles OC, Ross HJ, Lee D, Thavendiranathan P, Abdel-Qadir H. Prognosis Of Heart Failure Following Cardiotoxic Breast Cancer Chemotherapy: A Retrospective Matched Cohort Study Journal of the American College of Cardiology. 75: 708. DOI: 10.1016/S0735-1097(20)31335-8  0.393
2020 Bobrowski D, Zhou L, Austin P, Arguelles OC, Amir E, Lee D, Thavendiranathan P, Abdel-Qadir H. Statins Are Associated With Lower Risk Of Heart Failure After Anthracycline And Trastuzumab Chemotherapy For Early Stage Breast Cancer Journal of the American College of Cardiology. 75: 7. DOI: 10.1016/S0735-1097(20)30553-2  0.416
2019 Bobrowski D, Suntheralingam S, Calvillo-Argüelles O, Michalowska M, Amir E, Sacha Bhatia R, Thavendiranathan P, Abdel-Qadir H. The Yield of Routine Cardiac Imaging in Breast Cancer Patients Receiving Trastuzumab-based Treatment: A Retrospective Cohort Study. The Canadian Journal of Cardiology. PMID 32621888 DOI: 10.1016/J.Cjca.2019.12.021  0.391
2019 Tran B, Ruiz-Morales JM, Gonzalez-Billalabeitia E, Patrikidou A, Amir E, Seidel C, Bokemeyer C, Fankhauser C, Hermanns T, Rumyantsev A, Tryakin A, Brito M, Fléchon A, Kwan EM, Cheng T, et al. Large retroperitoneal lymphadenopathy and increased risk of venous thromboembolism in patients receiving first-line chemotherapy for metastatic germ cell tumors: A study by the global germ cell cancer group (G3). Cancer Medicine. PMID 31715650 DOI: 10.1002/Cam4.2674  0.332
2019 Tau N, Shochat T, Gafter-Gvili A, Amir E, Shepshelovich D. Undisclosed Financial Conflicts of Interest of Authors of Clinical Drug Trials Published in Influential Medical Journals: A Cohort Study. Mayo Clinic Proceedings. 94: 2272-2276. PMID 31685153 DOI: 10.1016/J.Mayocp.2019.08.025  0.307
2019 Saleh RR, Peinado P, Fuentes-Antrás J, Pérez-Segura P, Pandiella A, Amir E, Ocaña A. Prognostic Value of Lymphocyte-Activation Gene 3 (LAG3) in Cancer: A Meta-Analysis. Frontiers in Oncology. 9: 1040. PMID 31681578 DOI: 10.3389/Fonc.2019.01040  0.392
2019 Noblejas-López MDM, Nieto-Jiménez C, Morcillo García S, Pérez-Peña J, Nuncia-Cantarero M, Andrés-Pretel F, Galán-Moya EM, Amir E, Pandiella A, Győrffy B, Ocana A. Expression of MHC class I, HLA-A and HLA-B identifies immune-activated breast tumors with favorable outcome. Oncoimmunology. 8: e1629780. PMID 31646075 DOI: 10.1093/Annonc/Mdz253.090  0.343
2019 McNamara MG, Amir E. Response to letter to the editor: The impact of the nodal status and resection margin on the effectiveness of adjuvant chemotherapy for pancreatic cancer: It calls for more careful evaluation. Journal of Surgical Oncology. PMID 31471897 DOI: 10.1002/Jso.25691  0.339
2019 Shepshelovich D, Yahav D, Tibau A, Amir E. Assessment of frequency and reporting of design changes among clinical drug trials published in influential medical journals. European Journal of Internal Medicine. PMID 31439377 DOI: 10.1016/J.Ejim.2019.08.009  0.334
2019 Chia S, Bedard PL, Hilton J, Amir E, Gelmon K, Goodwin R, Villa D, Cabanero M, Tu D, Tsao M, Seymour L. A Phase Ib Trial of Durvalumab in Combination with Trastuzumab in HER2-Positive Metastatic Breast Cancer (CCTG IND.229). The Oncologist. PMID 31420468 DOI: 10.1634/Theoncologist.2019-0321  0.417
2019 Goldvaser H, Korzets Y, Shepshelovich D, Yerushalmi R, Sarfaty M, Ribnikar D, Thavendiranathan P, Amir E. Deescalating Adjuvant Trastuzumab in HER2-Positive Early-Stage Breast Cancer: A Systemic Review and Meta-Analysis. Jnci Cancer Spectrum. 3: pkz033. PMID 31360906 DOI: 10.1093/Jncics/Pkz033  0.414
2019 Abdel-Qadir H, Thavendiranathan P, Austin PC, Lee DS, Amir E, Tu JV, Fung K, Anderson GM. Development and validation of a multivariable prediction model for major adverse cardiovascular events after early stage breast cancer: a population-based cohort study. European Heart Journal. PMID 31318428 DOI: 10.1093/Eurheartj/Ehz460  0.368
2019 Rodríguez-Fernández IA, Rodríguez-Romo L, Hernandez-Barajas D, Gonzalez-Conchas GA, Verdines-Perez A, Templeton AJ, Ocana A, Seruga B, Tannock IF, Amir E, Vera-Badillo FE. Adjuvant Radiation Therapy After Radical Nephrectomy in Patients with Localized Renal Cell Carcinoma: A Systematic Review and Meta-analysis. European Urology Oncology. 2: 448-455. PMID 31277782 DOI: 10.1016/J.Euo.2018.10.003  0.46
2019 Srikanthan A, Amir E, Gupta A, Baxter N, Kennedy ED. Assisting with Decision-Making: How Standardized Information Impacts Breast Cancer Patient Decisions Regarding Fertility Trade-Offs and Chemotherapy. Journal of Adolescent and Young Adult Oncology. PMID 31241397 DOI: 10.1089/Jayao.2019.0027  0.37
2019 Saleh RR, Antrás JF, Peinado P, Pérez-Segura P, Pandiella A, Amir E, Ocaña A. Prognostic value of receptor tyrosine kinase-like orphan receptor (ROR) family in cancer: A meta-analysis. Cancer Treatment Reviews. 77: 11-19. PMID 31174180 DOI: 10.1016/J.Ctrv.2019.05.006  0.337
2019 Srikanthan A, Ethier JL, Amir E. The Voices of Young Women with Breast Cancer: Providing Support and Information for Improved Fertility Preservation Discussions. Journal of Adolescent and Young Adult Oncology. PMID 31158039 DOI: 10.1089/Jayao.2019.0030  0.374
2019 Ghate K, Amir E, Kuksis M, Hernandez-Barajas D, Rodriguez-Romo L, Booth CM, Vera-Badillo FE. PD-L1 expression and clinical outcomes in patients with advanced urothelial carcinoma treated with checkpoint inhibitors: A meta-analysis. Cancer Treatment Reviews. 76: 51-56. PMID 31125908 DOI: 10.1016/J.Ctrv.2019.05.002  0.301
2019 Goldvaser H, Amir E. Role of Bisphosphonates in Breast Cancer Therapy. Current Treatment Options in Oncology. 20: 26. PMID 30874905 DOI: 10.1007/s11864-019-0623-8  0.338
2019 Amir E. Endpoint selection in HER2-positive early breast cancer. The Lancet. Oncology. PMID 30709632 DOI: 10.1016/S1470-2045(18)30779-4  0.396
2019 Feng S, Cao Y, Amir E, Chen EX. Evaluating the value of checkpoint inhibitor therapy using the ASCO and ESMO frameworks. Journal of Clinical Oncology. 37: 17-17. DOI: 10.1200/Jco.2019.37.8_Suppl.17  0.363
2019 Al-Ezzi EM, Riromar JJA, Amir E, Fazelzad R, Hansen AR. Cross-trial comparison of taxane versus non-taxane combination chemotherapy regimens for advanced penile cancer (APC): A systematic review. Journal of Clinical Oncology. 37: 511-511. DOI: 10.1200/Jco.2019.37.7_Suppl.511  0.393
2019 Nadler M, Saleh R, Desnoyers A, Amir E. The efficacy and safety of exercise in metastatic solid cancer: A meta-analysis of randomized control trials. Journal of Clinical Oncology. 37: e23107-e23107. DOI: 10.1200/Jco.2019.37.15_Suppl.E23107  0.34
2019 Desnoyers A, Saleh R, Nadler M, Amir E. Associations with response to poly (ADP-ribose) polymerase (PARP) inhibitors in metastatic breast cancer: Results of a meta-regression analysis. Journal of Clinical Oncology. 37: e12567-e12567. DOI: 10.1200/Jco.2019.37.15_Suppl.E12567  0.434
2019 Feng S, Cao Y, Amir E, Chen EX. Evaluating the American Society of Clinical Oncology (ASCO) and European Society of Medical Oncology (ESMO) value frameworks for Food and Drug Administration (FDA) approved checkpoint inhibitors (CIs). Journal of Clinical Oncology. 37: 6624-6624. DOI: 10.1200/Jco.2019.37.15_Suppl.6624  0.374
2019 Molto C, Hwang TJ, Andres M, Borrell M, Gich Saladich IJ, Barnadas A, Amir E, Kesselheim AS, Tibau Martorell A. Clinical benefit of breakthrough cancer drugs approved by the United States Food and Drug Administration. Journal of Clinical Oncology. 37: 6513-6513. DOI: 10.1200/Jco.2019.37.15_Suppl.6513  0.414
2019 Goldvaser H, Yasmin KC, Shepshelovich D, Yerushalmi R, Sarfaty M, Ribnikar D, Thavendiranathan P, Amir E. De-escalating adjuvant trastuzumab in human epidermal growth factor receptor 2 (HER2)-positive early-stage breast cancer: A systemic review and meta-analysis. Journal of Clinical Oncology. 37: 524-524. DOI: 10.1200/Jco.2019.37.15_Suppl.524  0.424
2019 Lohmann AE, Soldera SV, Pimentel I, Ribnikar D, Ennis M, Amir E, Goodwin PJ. Association of obesity with breast cancer outcome in relation to cancer subtypes. Journal of Clinical Oncology. 37: 11557-11557. DOI: 10.1200/Jco.2019.37.15_Suppl.11557  0.383
2019 Tan TJY, Cescon DW, Wang L, Amir E, Vieira D, Zammit K, Warr D, Elser C, Butler MO, Abdul Razak AR, Hansen AR, Spreafico A, Siu LL, Bedard PL. Hyperprogressive disease in advanced triple-negative breast cancer (aTNBC) treated with immunotherapy (IO). Journal of Clinical Oncology. 37: 1086-1086. DOI: 10.1200/Jco.2019.37.15_Suppl.1086  0.432
2019 Ethier J, Parulekar W, Shepherd L, Summers L, Strasser-Weippl K, Tu D, Amir E. Abstract P4-14-03: Influence of competing risks of death on the interpretation of adjuvant endocrine therapy trials for breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P4-14-03  0.437
2019 Rodríguez AB, Tapia JC, Hwang T, Valiente CM, Templeton AJ, Barnadas A, Amir E, Tibau A. Change in magnitude of clinical benefit, overall survival (OS) and quality of life (QoL) between time of approval and post-marketing among cancer drugs approved by the US Food and Drug Administration (FDA) 2006-2015 Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz263.001  0.392
2019 McNamara MG, Jacobs T, Frizziero M, Pihlak R, Lamarca A, Hubner RA, Valle JW, Amir E. Prognostic and predictive impact of high tumor mutation burden (TMB) in solid tumors: A systematic review and meta-analysis Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz239  0.35
2019 Puts M, Strohschein F, Mclean B, Alqurini N, Syed AT, Amir E, Béland F, Berger A, Bergman S, Vanderbyl B, Breunis H, Elser C, Emmenegger U, Fung S, Hsu T, et al. Clinical And Cost-Effectiveness Of Comprehensive Geriatric Assessment And Management For Canadian Elders With Cancer: The 5C Study – Initial Recruitment And Implementation Results Journal of Geriatric Oncology. 10. DOI: 10.1016/S1879-4068(19)31271-8  0.32
2019 Nolan MT, Selam MA, Amir E, Koch A, Yip P, Michalowska M, Wintersperger B, Thavendiranathan P. CARDIOTOXICITY PHENOTYPES IN WOMEN TREATED WITH ANTHRACYCLINES AND TRASTUZUMAB FOR EARLY STAGE BREAST CANCER Journal of the American College of Cardiology. 73: 799. DOI: 10.1016/S0735-1097(19)31406-8  0.384
2019 Keilty D, Namini SN, Swain M, Maganti M, Cil T, McCready D, Cescon D, Amir E, Fleming R, Mulligan A, Levin W, Liu F, Croke J, Fyles A, Koch C, et al. Predictors of Survival and Patterns of Recurrence in Breast Cancer Treated with Neoadjuvant Chemotherapy, Surgery, and Radiation International Journal of Radiation Oncology*Biology*Physics. 105: E24-E25. DOI: 10.1016/J.Ijrobp.2019.06.671  0.377
2018 Molto Valiente C, Borrell M, Hwang T, Gich Saladich I, Barnadas A, Amir E, Kesselheim A, Tibau A. Magnitude of clinical benefit of trials supporting US Food and Drug Administration (FDA) approval of breakthrough and non-breakthrough drugs. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: viii564-viii565. PMID 32137486 DOI: 10.1093/Annonc/Mdy297.008  0.302
2018 Borrell Puy M, Molto Valiente C, Vokinger K, Hwang T, Ocana Fernandez A, Templeton AJ, Seruga B, Gich Saladich I, Barnadas A, Amir E, Tibau A. Magnitude of clinical benefit in trials supporting US Food and Drug Administration (FDA) accelerated approval (AA) and European Medicines Agency (EMA) conditional marketing authorisation (CMA) and subsequent trials supporting conversion to full approval. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: viii564. PMID 32137485 DOI: 10.1093/Annonc/Mdy297.007  0.318
2018 Shepshelovich D, Tibau A, Molto C, Goldvaser H, Ocana A, Šeruga B, Amir E. Assessment of Frequency and Reporting of Changes in Cancer Trial Design After Initiation of Patient Accrual. Jama Oncology. PMID 30520936 DOI: 10.1001/Jamaoncol.2018.5877  0.387
2018 Kitchlu A, McArthur E, Amir E, Booth CM, Sutradhar R, Majeed H, Nash DM, Silver SA, Garg AX, Chan CT, Kim SJ, Wald R. Acute Kidney Injury in Patients Receiving Systemic Treatment for Cancer: A Population-Based Cohort Study. Journal of the National Cancer Institute. PMID 30423160 DOI: 10.1093/Jnci/Djy167  0.337
2018 Goldvaser H, Ribnikar D, Majeed H, Ocaña A, Amir E. Absolute benefit from adjuvant chemotherapy in contemporary clinical trials: A systemic review and meta-analysis. Cancer Treatment Reviews. 71: 68-75. PMID 30366201 DOI: 10.1016/J.Ctrv.2018.10.010  0.418
2018 Liu S, Aghel N, Belford L, Silversides CK, Nolan M, Amir E, Maxwell C, Thavendiranathan P. Cardiac Outcomes in Pregnant Women With Treated Cancer. Journal of the American College of Cardiology. 72: 2087-2089. PMID 30336834 DOI: 10.1016/J.Jacc.2018.07.085  0.362
2018 Tibau A, Molto C, Borrell M, Del Paggio JC, Barnadas A, Booth CM, Amir E. Magnitude of Clinical Benefit of Cancer Drugs Approved by the US Food and Drug Administration Based on Single-Arm Trials. Jama Oncology. PMID 30267037 DOI: 10.1001/Jamaoncol.2018.4300  0.361
2018 Pérez-Peña J, Győrffy B, Amir E, Pandiella A, Ocaña A. Epigenetic modulation of FOXM1-gene interacting network by BET inhibitors in breast cancer. Breast Cancer Research and Treatment. PMID 30206781 DOI: 10.1007/S10549-018-4965-X  0.315
2018 Algorashi I, Goldvaser H, Ribnikar D, Cescon DW, Amir E. Evolution in sites of recurrence over time in breast cancer patients treated with adjuvant endocrine therapy. Cancer Treatment Reviews. 70: 138-143. PMID 30176513 DOI: 10.1016/J.Ctrv.2018.08.009  0.432
2018 Ocaña A, Amir E, Pandiella A. Dual targeting of HER2-positive breast cancer with trastuzumab emtansine and pertuzumab: understanding clinical trial results. Oncotarget. 9: 31915-31919. PMID 30159132 DOI: 10.18632/Oncotarget.25739  0.438
2018 Shepshelovich D, Amir E. Expedited approval of cancer drugs without randomized controlled trials: Too good to be true? Oncotarget. 9: 30942-30943. PMID 30123417 DOI: 10.18632/Oncotarget.25799  0.39
2018 Lohmann AE, Dowling RJO, Ennis M, Amir E, Elser C, Brezden-Masley C, Vandenberg T, Lee E, Fazaee K, Stambolic V, Goodwin PJ, Chang MC. Association of Metabolic, Inflammatory, and Tumor Markers With Circulating Tumor Cells in Metastatic Breast Cancer. Jnci Cancer Spectrum. 2: pky028. PMID 30035251 DOI: 10.1093/Jncics/Pky028  0.373
2018 Kitchlu A, Shapiro J, Amir E, Garg AX, Kim SJ, Wald R, Harel Z. Representation of Patients With Chronic Kidney Disease in Trials of Cancer Therapy. Jama. 319: 2437-2439. PMID 29922818 DOI: 10.1001/Jama.2018.7260  0.363
2018 Majeed H, Amir E. Personalized medicine in immuno-oncology: a novel prognostic index in non-small cell lung cancer. Journal of Thoracic Disease. 10: S995-S998. PMID 29849197 DOI: 10.21037/Jtd.2018.03.153  0.35
2018 Salah S, Lewin J, Amir E, Abdul Razak A. Tumor necrosis and clinical outcomes following neoadjuvant therapy in soft tissue sarcoma: A systematic review and meta-analysis. Cancer Treatment Reviews. 69: 1-10. PMID 29843049 DOI: 10.1016/J.Ctrv.2018.05.007  0.306
2018 Thavendiranathan P, Abdel-Qadir H, Fischer HD, Liu Y, Camacho X, Amir E, Austin PC, Lee DS. Risk-Imaging Mismatch in Cardiac Imaging Practices for Women Receiving Systemic Therapy for Early-Stage Breast Cancer: A Population-Based Cohort Study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2018779736. PMID 29791284 DOI: 10.1200/Jco.2018.77.9736  0.33
2018 Templeton AJ, Rodríguez-Lescure Á, Ruíz A, Alba E, Calvo L, Ruíz-Borrego M, Santaballa A, Rodríguez CA, Crespo C, Ramos M, Gracia-Marco JM, Lluch A, Álvarez I, Casas MI, Sánchez-Aragó M, ... ... Amir E, et al. Prognostic role for the derived neutrophil-to-lymphocyte ratio in early breast cancer: a GEICAM/9906 substudy. Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. PMID 29766456 DOI: 10.1007/S12094-018-1885-5  0.422
2018 Shepshelovich D, Tibau A, Goldvaser H, Molto C, Ocana A, Seruga B, Amir E. Postmarketing Modifications of Drug Labels for Cancer Drugs Approved by the US Food and Drug Administration Between 2006 and 2016 With and Without Supporting Randomized Controlled Trials. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2017775593. PMID 29641296 DOI: 10.1200/Jco.2017.77.5593  0.345
2018 Tibau A, Anguera G, Andrés-Pretel F, Templeton AJ, Seruga B, Barnadas A, Amir E, Ocana A. Role of cooperative groups and funding source in clinical trials supporting guidelines for systemic therapy of breast cancer. Oncotarget. 9: 15061-15067. PMID 29599926 DOI: 10.18632/Oncotarget.24589  0.421
2018 Martínez-Canales S, López de Rodas M, Nuncia-Cantarero M, Páez R, Amir E, Győrffy B, Pandiella A, Galán-Moya EM, Ocaña A. Functional transcriptomic annotation and protein-protein interaction analysis identify EZH2 and UBE2C as key upregulated proteins in ovarian cancer. Cancer Medicine. PMID 29575713 DOI: 10.1002/Cam4.1406  0.333
2018 Ethier JL, Ocaña A, Rodríguez Lescure A, Ruíz A, Alba E, Calvo L, Ruíz-Borrego M, Santaballa A, Rodríguez CA, Crespo C, Ramos M, Gracia Marco J, Lluch A, Álvarez I, Casas M, ... ... Amir E, et al. Outcomes of single versus double hormone receptor-positive breast cancer. A GEICAM/9906 sub-study. European Journal of Cancer (Oxford, England : 1990). 94: 199-205. PMID 29573665 DOI: 10.1016/J.Ejca.2018.02.018  0.39
2018 Majeed H, Amir E. EQUATOR-Oncology: reducing the latitude of cancer trial design and reporting. British Journal of Cancer. PMID 29471307 DOI: 10.1038/Bjc.2017.427  0.342
2018 Goldvaser H, Majeed H, Ribnikar D, Šeruga B, Ocaña A, Cescon DW, Amir E. Influence of control group therapy on the benefit from dose-dense chemotherapy in early breast cancer: a systemic review and meta-analysis. Breast Cancer Research and Treatment. PMID 29423899 DOI: 10.1007/S10549-018-4710-5  0.452
2018 Barua R, Templeton AJ, Seruga B, Ocana A, Amir E, Ethier JL. Hyperglycaemia and Survival in Solid Tumours: A Systematic Review and Meta-analysis. Clinical Oncology (Royal College of Radiologists (Great Britain)). PMID 29395413 DOI: 10.1200/Jco.2017.35.15_Suppl.E18158  0.343
2018 Srikanthan A, Amir E, Bedard P, Giuliani M, Hodgson D, Laframboise S, Prica A, Yee K, Greenblatt E, Lewin J, Gupta A. Fertility preservation in post-pubescent female cancer patients: A practical guideline for clinicians. Molecular and Clinical Oncology. 8: 153-158. PMID 29387409 DOI: 10.3892/Mco.2017.1486  0.373
2018 Lega IC, Austin PC, Fischer HD, Fung K, Krzyzanowska MK, Amir E, Lipscombe LL. The Impact of Diabetes on Breast Cancer Treatments and Outcomes: A Population-Based Study. Diabetes Care. PMID 29351960 DOI: 10.2337/Dc17-2012  0.365
2018 Goldvaser H, Barnes TA, Šeruga B, Cescon DW, Ocaña A, Ribnikar D, Amir E. Toxicity of Extended Adjuvant Therapy With Aromatase Inhibitors in Early Breast Cancer: A Systematic Review and Meta-analysis. Journal of the National Cancer Institute. 110. PMID 28922781 DOI: 10.1093/Jnci/Djx141  0.456
2018 Goldvaser H, Ribnikar D, Majeed H, Ocana A, Amir E. Absolute benefit from adjuvant chemotherapy in triple negative breast cancer (TNBC): A systemic review and meta-analysis. Journal of Clinical Oncology. 36: e12501-e12501. DOI: 10.1200/Jco.2018.36.15_Suppl.E12501  0.421
2018 Ribnikar D, Goldvaser H, Ocana A, Templeton AJ, Seruga B, Amir E. Safety and tolerability of cancer drugs studied in phase 3 randomized controlled trials (RCTs) over the last decade. Journal of Clinical Oncology. 36: 6588-6588. DOI: 10.1200/Jco.2018.36.15_Suppl.6588  0.377
2018 Veitch ZWN, Cescon DW, Elston S, Lien S, Yang C, Wang BX, Berman HK, Butler MO, Amir E, Elser C, Hakgor S, Giesler A, Pugh TJ, Ohashi PS, Siu LL, et al. Phase II (INSPIRE) trial of pembrolizumab (pembro) with serial immune and genomic profiling in patients (pts) with metastatic triple negative breast cancer (mTNBC). Journal of Clinical Oncology. 36: 1094-1094. DOI: 10.1200/Jco.2018.36.15_Suppl.1094  0.312
2018 Chia SKL, Bedard PL, Hilton J, Amir E, Gelmon KA, Goodwin RA, Villa D, Cabanero M, Ritter H, Tu D, Tsao MS, Seymour L. A phase I study of a PD-L1 antibody (Durvalumab) in combination with trastuzumab in HER-2 positive metastatic breast cancer (MBC) progressing on prior anti HER-2 therapies (CCTG IND.229)[NCT02649686]. Journal of Clinical Oncology. 36: 1029-1029. DOI: 10.1200/Jco.2018.36.15_Suppl.1029  0.339
2018 Goldvaser H, Ribnikar D, Fazelzad R, Seruga B, Templeton A, Ocana A, Amir E. Abstract P3-17-02: Influence of non-measurable disease on progression-free survival in patients with metastatic breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P3-17-02  0.393
2018 Goldvaser H, Algorashi I, Ribnikar D, Majeed H, Ocana A, Seruga B, Templeton A, Amir E. Abstract P3-12-04: Efficacy of extended adjuvant aromatase inhibitors in subgroups of women with early breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P3-12-04  0.396
2018 Molto Valiente C, Borrell M, Ocana Fernandez A, Templeton A, del Carpio L, Del Paggio J, Barnadas A, Booth C, Tibau A, Amir E. Magnitude of clinical benefit of cancer drugs approved based on single-arm trials (SAT) by the US Food and Drug Administration (FDA) Annals of Oncology. 29: viii564. DOI: 10.1093/Annonc/Mdy297.006  0.36
2018 Goldvaser H, Fyles A, Shepshelovich D, Amir E, Korzets Y. Toxicity and clinical outcomes of partial breast irradiation (PBI) compared to whole breast irradiation (WBI) for early stage breast cancer: A systematic review and meta-analysis. Annals of Oncology. 29. DOI: 10.1093/Annonc/Mdy270.241  0.401
2018 Meloche J, Nolan M, Amir E, Brezden-Masley C, Yan A, Thampinathan B, Woo A, Bernd W, Thavendiranathan P. TEMPORAL CHANGES IN LEFT ATRIAL FUNCTION IN WOMEN WITH HER2+ BREAST CANCER RECEIVING SEQUENTIAL ANTHRACYCLINES AND TRASTUZUMAB THERAPY Journal of the American College of Cardiology. 71: A1524. DOI: 10.1016/S0735-1097(18)32065-5  0.396
2018 Selam MA, Amir E, Brezden-Masley C, Connelly K, Michalowska M, Wintersperger BJ, Thavendiranathan P. VENTRICULAR REMODELING IN EARLY STAGE BREAST CANCER PATIENTS RECEIVING SEQUENTIAL ANTHRACYCLINE AND TRASTUZUMAB THERAPY: A CARDIAC MRI STUDY Journal of the American College of Cardiology. 71: A728. DOI: 10.1016/S0735-1097(18)31269-5  0.411
2018 Nolan MT, Meloche J, Amir E, Brezden CM, Thampinathan B, Michalowska M, Woo A, Wintersperger B, Thavendiranathan P. TEMPORAL CHANGES IN DIASTOLIC FUNCTION IN WOMEN WITH BREAST CANCER RECEIVING SEQUENTIAL THERAPY WITH ANTHRACYCLINE AND TRASTUZUMAB Journal of the American College of Cardiology. 71: A689. DOI: 10.1016/S0735-1097(18)31230-0  0.39
2018 Nolan MT, Aghel N, Amir E, Liu S, Silversides C, Maxwell C, Thavendiranathan P. PREGNANCY OUTCOMES IN PATIENTS WITH AND WITHOUT CANCER-TREATMENT-RELATED CARDIAC DYSFUNCTION: A SYSTEMATIC REVIEW AND META-ANALYSIS Journal of the American College of Cardiology. 71: A688. DOI: 10.1016/S0735-1097(18)31229-4  0.333
2018 Altaha M, Nolan M, Amir E, Connelly K, Brezden-Masley C, Yared K, Wintersperger B, Thavendiranathan P. LEFT AND RIGHT VENTRICULAR REMODELING IN PATIENTS WITH EARLY STAGE BREAST CANCER RECEIVING SEQUENTIAL ANTHRACYCLINE AND TRASTUZUMAB THERAPY - A CARDIAC MRI STUDY Canadian Journal of Cardiology. 34: S179-S180. DOI: 10.1016/J.Cjca.2018.07.133  0.369
2017 Zer A, Prince RM, Amir E, Abdul Razak AR. Multi-agent chemotherapy in advanced soft tissue sarcoma (STS) - A systematic review and meta-analysis. Cancer Treatment Reviews. 63: 71-78. PMID 29253836 DOI: 10.1016/J.Ctrv.2017.12.003  0.316
2017 Tibau A, Molto C, Ocana A, Templeton AJ, Del Carpio LP, Del Paggio JC, Barnadas A, Booth CM, Amir E. Magnitude of Clinical Benefit of Cancer Drugs Approved by the US Food and Drug Administration. Journal of the National Cancer Institute. PMID 29244173 DOI: 10.1093/Jnci/Djx232  0.311
2017 Perez-Peña J, Corrales-Sánchez V, Amir E, Pandiella A, Ocana A. Ubiquitin-conjugating enzyme E2T (UBE2T) and denticleless protein homolog (DTL) are linked to poor outcome in breast and lung cancers. Scientific Reports. 7: 17530. PMID 29235520 DOI: 10.1038/S41598-017-17836-7  0.401
2017 Porta-Sánchez A, Gilbert C, Spears D, Amir E, Chan J, Nanthakumar K, Thavendiranathan P. Incidence, Diagnosis, and Management of QT Prolongation Induced by Cancer Therapies: A Systematic Review. Journal of the American Heart Association. 6. PMID 29217664 DOI: 10.1161/Jaha.117.007724  0.402
2017 Pezo RC, Chen TW, Berman HK, Mulligan AM, Razak AA, Siu LL, Cescon DW, Amir E, Elser C, Warr DG, Sridhar SS, Yu C, Wang L, Stockley TL, Kamel-Reid S, et al. Impact of multi-gene mutational profiling on clinical trial outcomes in metastatic breast cancer. Breast Cancer Research and Treatment. PMID 29177603 DOI: 10.1007/S10549-017-4580-2  0.397
2017 Ribnikar D, Goldvaser H, Ocana A, Templeton AJ, Seruga B, Amir E. Reporting of Randomized Trials in Common Cancers in the Lay Media. Oncology. PMID 29151109 DOI: 10.1159/000484630  0.389
2017 Gonzalez-Conchas GA, Rodriguez-Romo L, Hernandez-Barajas D, Gonzalez-Guerrero JF, Rodriguez-Fernandez IA, Verdines-Perez A, Templeton AJ, Ocana A, Seruga B, Tannock IF, Amir E, Vera-Badillo FE. Epidermal growth factor receptor overexpression and outcomes in early breast cancer: A systematic review and a meta-analysis. Cancer Treatment Reviews. 62: 1-8. PMID 29126017 DOI: 10.1016/J.Ctrv.2017.10.008  0.51
2017 Srikanthan A, Mai H, Penner N, Amir E, Laupacis A, Sabharwal M, Chan KKW. Impact of the pan-Canadian Oncology Drug Review on provincial concordance with respect to cancer drug funding decisions and time to funding. Current Oncology (Toronto, Ont.). 24: 295-301. PMID 29089796 DOI: 10.3747/Co.24.3648  0.313
2017 Goldvaser H, AlGorashi I, Ribnikar D, Seruga B, Templeton AJ, Ocana A, Amir E. Efficacy of extended adjuvant therapy with aromatase inhibitors in early breast cancer among common clinicopathologically-defined subgroups: A systematic review and meta-analysis. Cancer Treatment Reviews. 60: 53-59. PMID 28881223 DOI: 10.1016/J.Ctrv.2017.08.008  0.46
2017 Puts MTE, Sattar S, Kulik M, MacDonald ME, McWatters K, Lee K, Brennenstuhl S, Jang R, Amir E, Krzyzanowska MK, Joshua AM, Monette J, Wan-Chow-Wah D, Alibhai SMH. A randomized phase II trial of geriatric assessment and management for older cancer patients. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. PMID 28741175 DOI: 10.1007/S00520-017-3820-7  0.327
2017 Goldvaser H, Ribnikar D, Fazelzad R, Seruga B, Templeton AJ, Ocana A, Amir E. Influence of non-measurable disease on progression-free survival in patients with metastatic breast cancer. Cancer Treatment Reviews. 59: 46-53. PMID 28734183 DOI: 10.1016/J.Ctrv.2017.06.007  0.39
2017 Barnes TA, Amir E. HYPE or HOPE: the prognostic value of infiltrating immune cells in cancer. British Journal of Cancer. PMID 28704840 DOI: 10.1038/Bjc.2017.220  0.32
2017 Ethier JL, Desautels DN, Amir E, MacKay H. Is hormonal therapy effective in advanced endometrial cancer? A systematic review and meta-analysis. Gynecologic Oncology. PMID 28689667 DOI: 10.1016/J.Ygyno.2017.07.002  0.348
2017 Natori A, Ethier JL, Amir E, Cescon DW. Capecitabine in early breast cancer: A meta-analysis of randomised controlled trials. European Journal of Cancer (Oxford, England : 1990). 77: 40-47. PMID 28355581 DOI: 10.1016/j.ejca.2017.02.024  0.341
2017 Ethier JL, Prince RM, Amir E. Bone Modifier Use as Adjuvant Therapy for Early Breast Cancer. Current Oncology Reports. 19: 15. PMID 28251493 DOI: 10.1007/s11912-017-0577-6  0.316
2017 Ethier JL, Desautels D, Templeton A, Shah PS, Amir E. Prognostic role of neutrophil-to-lymphocyte ratio in breast cancer: a systematic review and meta-analysis. Breast Cancer Research : Bcr. 19: 2. PMID 28057046 DOI: 10.1186/S13058-016-0794-1  0.426
2017 Alcaraz-Sanabria AL, Nieto-Jimenez C, Corrales-Sanchez V, Serrano-Oviedo L, Serrano-Heras G, Pretel FA, Montero JC, Burgos M, Llopis J, Galan-Moya EM, Amir E, Pandiella A, Ocana A. Synthetic lethality interaction between aurora kinases and CHEK1 inhibitors in ovarian cancer. Journal of Clinical Oncology. 35. DOI: 10.1200/Jco.2017.35.15_Suppl.E17089  0.303
2017 Goldvaser H, Ribnikar D, Barnes TA, Cescon DW, Ocana A, Amir E. Toxicity of extended adjuvant aromatase inhibitors therapy in postmenopausal breast cancer patients: A systematic review and meta-analysis. Journal of Clinical Oncology. 35: 549-549. DOI: 10.1200/Jco.2017.35.15_Suppl.549  0.467
2017 Flaum N, Hubner R, Valle JW, Amir E, McNamara MG. Adjuvant chemotherapy and outcome in patients (pts) with nodal (N-) and resection margin negative (R0) pancreatic adenocarcinoma (PC): A systematic review and meta-analysis. Journal of Clinical Oncology. 35: 4114-4114. DOI: 10.1200/Jco.2017.35.15_Suppl.4114  0.32
2017 Natori A, Ethier J, Amir E, Cescon D. Abstract P5-14-05: Capecitabine in early breast cancer: A meta-analysis of randomized controlled trials Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P5-14-05  0.427
2017 Stjepanovic N, Kim R, Wilson M, Mandilaras V, Berman H, Amir E, Cescon D, Elser C, Armel SR, McCuaig J, Volenik A, Demsky R, Chow H, Misyura M, Wang L, et al. Abstract P3-09-05: Clinical outcome of patients with advanced triple negative breast cancer with germline and somatic variants in homologous recombination gene Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P3-09-05  0.371
2017 Stjepanovic N, Garg S, Berman H, Warr D, Amir E, Cescon D, Elser C, Wang L, Kamel-Reid S, Siu L, Bedard P, Stockley T. Abstract P2-05-19: Impact of TP53 functional mutation type on clinical outcomes of advanced breast cancer patients Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P2-05-19  0.391
2017 Paoletti C, Regan M, Liu M, Marcom P, Hart L, Smith J, Tedesco K, Amir E, Krop I, DeMichele A, Goodwin P, Block M, Aung K, Cannell E, Darga E, et al. Abstract P1-01-01: Circulating tumor cell number and CTC-endocrine therapy index predict clinical outcomes in ER positive metastatic breast cancer patients: Results of the COMETI Phase 2 trial Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-01-01  0.434
2017 Abdel-Qadir H, Thavendiranathan P, Austin P, Lee D, Amir E, Tu J, Ma H, Fung K, Anderson G. 2020The spectrum of cardiovascular disease after early stage breast cancer: a population-based cohort study European Heart Journal. 38. DOI: 10.1093/Eurheartj/Ehx502.2020  0.367
2017 Puy MB, Valiente CM, Fernandez AO, Templeton A, Seruga B, Gich I, Barnadas A, Amir E, Tibau A. Clinical benefit of randomized controlled trials (RCT) supporting US Food and Drug Administration (FDA) conversion from accelerated to full approval Annals of Oncology. 28: v642. DOI: 10.1093/Annonc/Mdx440.065  0.315
2017 Valiente CM, Tibau A, Fernandez AO, Templeton A, del Carpio Huerta L, Del Paggio J, Barnadas A, Booth C, Amir E. Comparison of the European Society for Medical Oncology Magnitude of Clinical Benefit Scale (ESMO-MCBS) in clinical trials supporting US Food and Drug Administration (FDA) approval of orphan vs. non-orphan drugs Annals of Oncology. 28: v642. DOI: 10.1093/Annonc/Mdx440.063  0.31
2017 Ribnikar D, Goldvaser H, Ocana Fernandez A, Templeton A, Seruga B, Amir E. Reporting of results of randomized trials in common cancers in the lay media Annals of Oncology. 28: v513. DOI: 10.1093/Annonc/Mdx385.005A  0.389
2017 Molto Valiente C, Amir E, Ocana Fernandez A, Templeton A, del Carpio Huerta L, Del Paggio J, Barnadas A, Booth C, Tibau A. Magnitude of clinical benefit of randomized controlled trials supporting US Food and Drug Administration approval of drugs for solid tumours Annals of Oncology. 28: v511. DOI: 10.1093/Annonc/Mdx385.001  0.312
2017 Abdel-Qadir H, Austin P, Thavendiranathan P, Fang J, Fung K, Amir E, Lee D, Tu J, Anderson G. A RISK SCORE FOR PREDICTING CARDIOVASCULAR EVENTS AFTER EARLY STAGE BREAST CANCER Canadian Journal of Cardiology. 33: S25-S26. DOI: 10.1016/J.Cjca.2017.07.071  0.367
2016 Prince RM, Amir E. Update in treatment of early breast cancer in post-menopausal women. Expert Review of Endocrinology & Metabolism. 11: 243-252. PMID 30058935 DOI: 10.1080/17446651.2016.1175937  0.403
2016 Thavendiranathan P, Amir E. Left Ventricular Dysfunction With Trastuzumab Therapy: Is Primary Prevention the Best Option? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016710038. PMID 28029315 DOI: 10.1200/Jco.2016.71.0038  0.395
2016 Tannock IF, Amir E, Booth CM, Niraula S, Ocana A, Seruga B, Templeton AJ, Vera-Badillo F. Relevance of randomised controlled trials in oncology. The Lancet. Oncology. 17: e560-e567. PMID 27924754 DOI: 10.1016/S1470-2045(16)30572-1  0.522
2016 Abdel-Qadir H, Austin PC, Lee DS, Amir E, Tu JV, Thavendiranathan P, Fung K, Anderson GM. A Population-Based Study of Cardiovascular Mortality Following Early-Stage Breast Cancer. Jama Cardiology. PMID 27732702 DOI: 10.1001/Jamacardio.2016.3841  0.385
2016 Abdel-Qadir H, Amir E, Fischer HD, Fu L, Austin PC, Harvey PJ, Rochon PA, Lee DS, Anderson GM. The risk of myocardial infarction with aromatase inhibitors relative to tamoxifen in post-menopausal women with early stage breast cancer. European Journal of Cancer (Oxford, England : 1990). 68: 11-21. PMID 27693889 DOI: 10.1016/J.Ejca.2016.08.022  0.395
2016 Vera-Badillo FE, Napoleone M, Krzyzanowska MK, Alibhai SM, Chan AW, Ocana A, Templeton AJ, Seruga B, Amir E, Tannock IF. Honorary and ghost authorship in reports of randomised clinical trials in oncology. European Journal of Cancer (Oxford, England : 1990). 66: 1-8. PMID 27500368 DOI: 10.1016/J.Ejca.2016.06.023  0.478
2016 Seruga B, Templeton AJ, Badillo FE, Ocana A, Amir E, Tannock IF. Under-reporting of harm in clinical trials. The Lancet. Oncology. 17: e209-19. PMID 27301048 DOI: 10.1016/S1470-2045(16)00152-2  0.515
2016 Gómez García S, Clemons M, Amir E. Rethinking end-points for bone-targeted therapy in advanced cancer. European Journal of Cancer (Oxford, England : 1990). 63: 105-109. PMID 27299662 DOI: 10.1016/J.Ejca.2016.05.014  0.352
2016 Ethier JL, Amir E. The Role of the 21-Gene Recurrence Score in Breast Cancer Treatment. Molecular Diagnosis & Therapy. PMID 27235162 DOI: 10.1007/S40291-016-0209-0  0.412
2016 Srikanthan A, Amir E, Warner E. Does a dedicated program for young breast cancer patients affect the likelihood of fertility preservation discussion and referral? Breast (Edinburgh, Scotland). 27: 22-6. PMID 27212696 DOI: 10.1016/J.Breast.2016.02.012  0.366
2016 Ocana A, Amir E, Tannock IF. Toward Value-Based Pricing to Boost Cancer Research and Innovation. Cancer Research. 76: 3127-9. PMID 27197164 DOI: 10.1158/0008-5472.Can-15-3179  0.476
2016 Nathan PC, Amir E, Abdel-Qadir H. Cardiac Outcomes in Survivors of Pediatric and Adult Cancers. The Canadian Journal of Cardiology. PMID 27179545 DOI: 10.1016/J.Cjca.2016.02.065  0.349
2016 Vera-Badillo FE, Napoleone M, Krzyzanowska MK, Alibhai SM, Chan AW, Ocana A, Seruga B, Templeton AJ, Amir E, Tannock IF. Bias in reporting of randomised clinical trials in oncology. European Journal of Cancer (Oxford, England : 1990). 61: 29-35. PMID 27151552 DOI: 10.1016/J.Ejca.2016.03.066  0.526
2016 Templeton AJ, Gonzalez LD, Vera-Badillo FE, Tibau A, Goldstein R, Šeruga B, Srikanthan A, Pandiella A, Amir E, Ocana A. Interaction between Hormonal Receptor Status, Age and Survival in Patients with BRCA1/2 Germline Mutations: A Systematic Review and Meta-Regression. Plos One. 11: e0154789. PMID 27149669 DOI: 10.1371/Journal.Pone.0154789  0.324
2016 Abdel-Qadir H, Amir E, Thavendiranathan P. Prevention, Detection, and Management of Chemotherapy-Related Cardiac Dysfunction. The Canadian Journal of Cardiology. PMID 27118058 DOI: 10.1016/J.Cjca.2016.01.028  0.356
2016 Ocaña A, Pérez-Peña J, Alcaraz-Sanabria A, Sánchez-Corrales V, Nieto-Jiménez C, Templeton AJ, Seruga B, Pandiella A, Amir E. In silico analyses identify gene-sets, associated with clinical outcome in ovarian cancer: role of mitotic kinases. Oncotarget. PMID 26992217 DOI: 10.18632/Oncotarget.8118  0.373
2016 Zer A, Prince RM, Amir E, Abdul Razak A. Evolution of Randomized Trials in Advanced/Metastatic Soft Tissue Sarcoma: Endpoint Selection, Surrogacy, and Quality of Reporting. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26951308 DOI: 10.1200/Jco.2015.64.3437  0.322
2016 Graham J, Pitz M, Gordon V, Grenier D, Amir E, Niraula S. Clinical predictors of benefit from fulvestrant in advanced breast cancer: A Meta-analysis of randomized controlled trials. Cancer Treatment Reviews. 45: 1-6. PMID 26922660 DOI: 10.1016/J.Ctrv.2016.02.004  0.445
2016 Ocaña A, Pérez-Peña J, Díez-González L, Sánchez-Corrales V, Templeton A, Seruga B, Amir E, Pandiella A. Transcriptomic analyses identify association between mitotic kinases, PDZ-binding kinase and BUB1, and clinical outcome in breast cancer. Breast Cancer Research and Treatment. 156: 1-8. PMID 26897635 DOI: 10.1007/S10549-016-3720-4  0.325
2016 Srikanthan A, Vera-Badillo F, Ethier J, Goldstein R, Templeton AJ, Ocana A, Seruga B, Amir E. Evolution in the eligibility criteria of randomized controlled trials for systemic cancer therapies Cancer Treatment Reviews. 43: 67-73. PMID 26827694 DOI: 10.1016/J.Ctrv.2015.12.006  0.372
2016 AlHashem HY, Al-Mubarak M, Vera-Badillo FE, Templeton AJ, Ocana A, Seruga B, Amir E. Impact of Geographic Region on Benefit of Approved Anticancer Drugs Evaluated in International Phase III Clinical Trials. Clinical Oncology (Royal College of Radiologists (Great Britain)). 28: 283-91. PMID 26542275 DOI: 10.1016/J.Clon.2015.09.010  0.322
2016 Tran B, Ruiz Morales JM, González-Billalabeitia E, Amir E, Seidel CA, Bokemeyer C, Fankhauser CD, Hermanns T, Rumyantsev A, Tryakin A, Goncalves MB, Fléchon A, Cheng T, Castellano DE, Garcia del Muro X, et al. Large retroperitoneal lymphadenopathy (RPLN) and increased risk of venous thromboembolism (VTE) in patients (pts) with metastatic germ cell tumours (mGCT): A Global Germ Cell Cancer Group (G3) Study. Journal of Clinical Oncology. 34: e16058-e16058. DOI: 10.1200/Jco.2016.34.15_Suppl.E16058  0.312
2016 Ethier J, Ocana A, Casas M, Sanchez-Arago M, Caballero R, Rodriguez-Lescure A, Ruiz A, Alba E, Calvo L, Ruiz M, Santaballa A, Rodriguez CA, Crespo C, Ramos Vazquez M, Gracia JM, ... ... Amir E, et al. Outcomes of single versus double hormone receptor positive breast cancer. Journal of Clinical Oncology. 34: 569-569. DOI: 10.1200/Jco.2016.34.15_Suppl.569  0.405
2016 Prince RM, DÃez L, Alcaraz-Sanabria A, Ethier J, Ocana A, Seruga B, Templeton AJ, Amir E. Treatment-related side effects as predictors of efficacy of check-point inhibitors (CPIs). Journal of Clinical Oncology. 34: 3062-3062. DOI: 10.1200/Jco.2016.34.15_Suppl.3062  0.315
2016 Srikanthan A, Amir E, Warner E. Abstract P6-12-02: Association between a dedicated program for young breast cancer patients and discussion about fertility preservation Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P6-12-02  0.417
2016 Niraula S, Pitz M, Gordon V, Grenier D, Amir E, Brandes L. Abstract P5-14-02: Clinical predictors of benefit from fulvestrant in advanced breast cancer: A meta-analysis of randomized controlled trials Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P5-14-02  0.491
2016 Srikanthan A, Bedard P, Goldstein S, Templeton A, Amir E. Abstract P2-08-05: Association between the neutrophil-to-lymphocyte ratio (NLR) and the 21-gene recurrence score Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P2-08-05  0.358
2016 Lohmann A, Chang M, Dowling R, Ennis M, Amir E, Elser C, Brezden-Masley C, Vandenberg T, Lee E, Fazae K, Stambolic V, Goodwin P. Abstract P2-02-12: Association of inflammatory and tumor markers with circulating tumor cells in metastatic breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P2-02-12  0.387
2016 Dowling R, Chang M, Lohmann A, Ennis M, Amir E, Elser C, Brezden-Masley C, Vandenberg T, Lee E, Fazaee K, Stambolic V, Goodwin P. Abstract P2-02-09: Obesity associated factors are inversely associated with circulating tumor cells in metastatic breast cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P2-02-09  0.343
2016 Fernandez AO, Templeton A, Casas M, Sánchez-Aragó M, Caballero R, Lescure AR, Ruiz A, Alba E, Calvo L, Ruiz M, Santaballa A, Rodríguez C, Crespo C, Ramos M, Marco JG, ... ... Amir E, et al. Prognostic role for derived neutrophil-to-lymphocyte ratio in early breast cancer Annals of Oncology. 27: vi43. DOI: 10.1093/Annonc/Mdw364.02  0.404
2015 Zist A, Amir E, Ocana AF, Seruga B. Impact of comorbidity on the outcome in men with advanced prostate cancer treated with docetaxel. Radiology and Oncology. 49: 402-8. PMID 26834528 DOI: 10.1515/Raon-2015-0038  0.311
2015 Jacobs C, Amir E, Paterson A, Zhu X, Clemons M. Are adjuvant bisphosphonates now standard of care of women with early stage breast cancer? A debate from the Canadian Bone and the Oncologist New Updates meeting. Journal of Bone Oncology. 4: 54-58. PMID 26579489 DOI: 10.1016/J.Jbo.2015.06.001  0.422
2015 Seruga B, Ocana A, Amir E, Tannock IF. Failures in Phase III: Causes and Consequences. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 4552-60. PMID 26473191 DOI: 10.1158/1078-0432.Ccr-15-0124  0.519
2015 Ocana A, Ethier JL, Díez-González L, Corrales-Sánchez V, Srikanthan A, Gascón-Escribano MJ, Templeton AJ, Vera-Badillo F, Seruga B, Niraula S, Pandiella A, Amir E. Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses. Oncotarget. 6: 39538-49. PMID 26446908 DOI: 10.18632/Oncotarget.5946  0.373
2015 Dupuy F, Tabariès S, Andrzejewski S, Dong Z, Blagih J, Annis MG, Omeroglu A, Gao D, Leung S, Amir E, Clemons M, Aguilar-Mahecha A, Basik M, Vincent EE, St-Pierre J, et al. PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer. Cell Metabolism. 22: 577-89. PMID 26365179 DOI: 10.1016/J.Cmet.2015.08.007  0.348
2015 Calleja A, Poulin F, Khorolsky C, Shariat M, Bedard PL, Amir E, Rakowski H, McDonald M, Delgado D, Thavendiranathan P. Right Ventricular Dysfunction in Patients Experiencing Cardiotoxicity during Breast Cancer Therapy. Journal of Oncology. 2015: 609194. PMID 26339242 DOI: 10.1155/2015/609194  0.376
2015 Ocana A, Vera-Badillo F, Templeton A, Tannock I, Amir E. Response. Journal of the National Cancer Institute. 107. PMID 26283612 DOI: 10.1093/jnci/djv244  0.303
2015 Dranitsaris G, Cohen RB, Acton G, Keltner L, Price M, Amir E, Podack ER, Schreiber TH. Statistical Considerations in Clinical Trial Design of Immunotherapeutic Cancer Agents. Journal of Immunotherapy (Hagerstown, Md. : 1997). 38: 259-66. PMID 26261889 DOI: 10.1097/Cji.0000000000000089  0.403
2015 Abdel-Qadir H, Amir E, Thavendiranathan P. The use of myocardial strain and newer echocardiography imaging techniques in cancer patients. Future Oncology (London, England). 11: 2035-41. PMID 26198833 DOI: 10.2217/Fon.15.122  0.369
2015 Chan M, Chang MC, González R, Lategan B, del Barco E, Vera-Badillo F, Quesada P, Goldstein R, Cruz I, Ocana A, Cruz JJ, Amir E. Outcomes of Estrogen Receptor Negative and Progesterone Receptor Positive Breast Cancer. Plos One. 10: e0132449. PMID 26161666 DOI: 10.1371/Journal.Pone.0132449  0.354
2015 Niraula S, Ocana A, Amir E. One step forward, two steps back: The story of everolimus in advanced breast cancer. Breast (Edinburgh, Scotland). 24: 529-31. PMID 26112664 DOI: 10.1016/J.Breast.2015.04.006  0.422
2015 Vera-Badillo FE, Chang MC, Kuruzar G, Ocana A, Templeton AJ, Seruga B, Goldstein R, Bedard PL, Tannock IF, Amir E. Association between androgen receptor expression, Ki-67 and the 21-gene recurrence score in non-metastatic, lymph node-negative, estrogen receptor-positive and HER2-negative breast cancer. Journal of Clinical Pathology. PMID 26076967 DOI: 10.1136/Jclinpath-2015-203012  0.526
2015 Jacobs C, Hutton B, Mazzarello S, Smith S, Joy A, Amir E, Ibrahim MF, Gregario N, Daigle K, Eggert L, Clemons M. Optimisation of steroid prophylaxis schedules in breast cancer patients receiving docetaxel chemotherapy-a survey of health care providers and patients. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. PMID 25933700 DOI: 10.1007/S00520-015-2731-8  0.382
2015 Srikanthan A, Ethier JL, Ocana A, Seruga B, Krzyzanowska MK, Amir E. Cardiovascular toxicity of multi-tyrosine kinase inhibitors in advanced solid tumors: a population-based observational study. Plos One. 10: e0122735. PMID 25815472 DOI: 10.1371/Journal.Pone.0122735  0.334
2015 Ocaña A, Diez-Gónzález L, Adrover E, Fernández-Aramburo A, Pandiella A, Amir E. Tumor-infiltrating lymphocytes in breast cancer: ready for prime time? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 1298-9. PMID 25753437 DOI: 10.1200/Jco.2014.59.7286  0.389
2015 Templeton AJ, Ace O, Amir E, Vera-Badillo F, Ocana A, Pond GR, Tannock IF. Influence of censoring on conclusions of trials for women with metastatic breast cancer. European Journal of Cancer (Oxford, England : 1990). 51: 721-4. PMID 25728257 DOI: 10.1016/J.Ejca.2014.12.016  0.583
2015 Ocana A, Seruga B, Amir E. Pathological complete response in breast cancer. Lancet (London, England). 385: 113. PMID 25706463 DOI: 10.1016/S0140-6736(15)60015-0  0.43
2015 Srikanthan A, Tran B, Beausoleil M, Jewett MA, Hamilton RJ, Sturgeon JF, O'Malley M, Anson-Cartwright L, Chung PW, Warde PR, Winquist E, Moore MJ, Amir E, Bedard PL. Large retroperitoneal lymphadenopathy as a predictor of venous thromboembolism in patients with disseminated germ cell tumors treated with chemotherapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 582-7. PMID 25605848 DOI: 10.1200/Jco.2014.58.6537  0.315
2015 van Soest RJ, Templeton AJ, Vera-Badillo FE, Mercier F, Sonpavde G, Amir E, Tombal B, Rosenthal M, Eisenberger MA, Tannock IF, de Wit R. Neutrophil-to-lymphocyte ratio as a prognostic biomarker for men with metastatic castration-resistant prostate cancer receiving first-line chemotherapy: data from two randomized phase III trials. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 743-9. PMID 25515657 DOI: 10.1093/Annonc/Mdu569  0.521
2015 Vera-Badillo FE, Templeton AJ, Duran I, Ocana A, de Gouveia P, Aneja P, Knox JJ, Tannock IF, Escudier B, Amir E. Systemic therapy for non-clear cell renal cell carcinomas: a systematic review and meta-analysis. European Urology. 67: 740-9. PMID 24882670 DOI: 10.1016/J.Eururo.2014.05.010  0.463
2015 Blanchette PS, Lo A, Ng P, Razak A, Amir E, Hogg D, Blackstein ME, Gupta AA. Irinotecan and temozolomide in adults with recurrent sarcoma Journal of Solid Tumors. 5. DOI: 10.5430/Jst.V5N2P105  0.307
2015 Alimohamed NS, Templeton AJ, Knox JJ, Lin X, Simantov R, Xie W, Lawrence NJ, Broom RJ, Fay AP, Rini BI, Bjarnason GA, Smoragiewicz M, Kollmannsberger CK, Kanesvaran R, Wells C, ... Amir E, et al. Change in neutrophil to lymphocyte ratio as a prognostic and predictive marker in response to targeted therapy for metastatic renal cell carcinoma. Journal of Clinical Oncology. 33: 404-404. DOI: 10.1200/Jco.2015.33.7_Suppl.404  0.338
2015 Puts M, Sattar S, McWatters K, Lee K, Amir E, Krzyzanowska MK, Joshua AM, Monette J, Wan-Chow-Wah D, Jang RW, Alibhai SM. A feasibility trial of geriatric assessment and integrated care plan for older cancer patients. Journal of Clinical Oncology. 33: TPS9634-TPS9634. DOI: 10.1200/Jco.2015.33.15_Suppl.Tps9634  0.373
2015 Clarke KV, Amir E, Berman HK, Maganti M, Sridhar SS. Association between pretreatment neutrophil to lymphocyte ratio (NLR) and complete pathological response (pCR) in breast cancer patients treated with neoadjuvant chemotherapy (NACT). Journal of Clinical Oncology. 33: e11588-e11588. DOI: 10.1200/Jco.2015.33.15_Suppl.E11588  0.438
2015 Srikanthan A, Amir E, Gupta AA, Baxter NN, Kennedy ED. The price of survival: Breast cancer patient preferences about fertility. Journal of Clinical Oncology. 33: 9561-9561. DOI: 10.1200/Jco.2015.33.15_Suppl.9561  0.409
2015 Stjepanovic N, Wilson MK, Oza AM, Clarke B, Berman HK, Amir E, Mackay H, Shaw P, Butler MO, Mulligan AM, Milea A, Ahmed L, Volenik A, Wang L, Pugh TJ, et al. Somatic mutation profiling of advanced breast and ovarian cancers according to germline BRCA1/2 mutation status. Journal of Clinical Oncology. 33: 1532-1532. DOI: 10.1200/Jco.2015.33.15_Suppl.1532  0.365
2015 Zer A, Prince RM, Amir E, Razak ARA. Forty years of randomized trials in advanced/metastatic soft tissue sarcoma (STS): Endpoint selection, surrogacy and quality of reporting. Journal of Clinical Oncology. 33: 10513-10513. DOI: 10.1200/Jco.2015.33.15_Suppl.10513  0.345
2015 McNamara M, Backen A, Lamarca A, Hubner R, Valle J, Amir E. 2293 Targeting the epidermal growth factor receptor (EGFR) in addition to chemotherapy in patients (pts) with advanced pancreas cancer: A systematic review and meta-analysis European Journal of Cancer. 51: S430. DOI: 10.1016/S0959-8049(16)31209-6  0.347
2015 Vera Badillo F, Gonzalez-Guerrero J, Gonzalez-Conchas G, Rodriguez-Fernandez I, Verdines-Perez A, Templeton A, Ocana A, Seruga B, Tannock I, Amir E. 1973 Epidermal growth factor receptor (EGFR) over-expression and outcomes in early breast cancer: A systematic review and meta-analysis European Journal of Cancer. 51: S324-S325. DOI: 10.1016/S0959-8049(16)30921-2  0.527
2015 Guerra R, Toloi D, Tibau A, Ocana A, Seruga B, Vera-Badillo F, Amir E, Tannock I, Templeton A. 1229 Industry-Sponsored Posters at Major Oncology Conferences: Science or Marketing? European Journal of Cancer. 51: S183. DOI: 10.1016/S0959-8049(16)30533-0  0.401
2015 Anguera G, Tibau A, Andrés-Pretel F, Andrés M, Seruga B, Templeton A, Jerez Y, Vera-Badillo F, Barnadas A, Martin M, Amir E, Ocańa A. 1215 Role of cooperative groups and funding source in clinical studies that support approved therapy for breast cancer European Journal of Cancer. 51: S176-S177. DOI: 10.1016/S0959-8049(16)30519-6  0.413
2015 Ethier J, Dýez-González L, Corrales-Sánchez V, Srikanthan A, Gascón-Escribano M, Templeton A, Vera-Badillo F, Seruga B, Niraula S, Pandiella A, Amir E, Ocana A. 1204 Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs European Journal of Cancer. 51: S172-S173. DOI: 10.1016/S0959-8049(16)30508-1  0.338
2015 Calleja A, Poulin F, Khorolsky K, Bedard PL, Shariat M, Amir E, Rakowski H, McDonald M, Delgado D, Thavendiranathan P. RIGHT VENTRICULAR DYSFUNCTION IN PATIENTS WITH BREAST CANCER EXPERIENCING CARDIOTOXICITY DURING TRASTUZUMAB THERAPY Journal of the American College of Cardiology. 65: A940. DOI: 10.1016/S0735-1097(15)60940-8  0.357
2014 Hansen A, Geddie W, Boerner S, Ghai S, Berman H, Serra S, Roehrl M, Joshua AM, Oza AM, Moore M, Amir E, Usmani T, Giesler A, Amin N, Zhang T, et al. 1612PFINE NEEDLE BIOPSIES ARE FEASIBLE AS A MINIMALLY INVASIVE MEANS FOR TARGETED NEXT GENERATION SEQUENCING IN ADVANCED SOLID TUMORS. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv558. PMID 28172381 DOI: 10.1093/Annonc/Mdu358.43  0.318
2014 Templeton A, Knox J, Mitchell N, Broom R, Choueiri TK, McDermott DF, Fay A, Rini BI, Alvarez A, Bjarnason GA, Smoragiewicz M, Kollmannsberger CK, Kanesvaran R, North S, Alimohamed N, ... ... Amir E, et al. 817PPROGNOSTIC IMPACT OF CHANGE IN NEUTROPHIL TO LYMPHOCYTE RATIO (NLR) IN RESPONSE TO TARGETED THERAPY FOR METASTATIC RENAL CELL CARCINOMA (MRCC). Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv284. PMID 28172100 DOI: 10.1093/Annonc/Mdu337.10  0.308
2014 Zhu X, Amir E, Singh G, Clemons M, Addison C. Bone-targeted therapy for metastatic breast cancer-Where do we go from here? A commentary from the BONUS 8 meeting. Journal of Bone Oncology. 3: 1-4. PMID 26909291 DOI: 10.1016/J.Jbo.2014.01.001  0.36
2014 Addison CL, Pond GR, Zhao H, Mazzarello S, Vandermeer L, Goldstein R, Amir E, Clemons M. Effects of de-escalated bisphosphonate therapy on bone turnover biomarkers in breast cancer patients with bone metastases. Springerplus. 3: 577. PMID 25332877 DOI: 10.1186/2193-1801-3-577  0.33
2014 Niraula S, Amir E, Vera-Badillo F, Seruga B, Ocana A, Tannock IF. Risk of incremental toxicities and associated costs of new anticancer drugs: a meta-analysis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 3634-42. PMID 25267757 DOI: 10.1200/Jco.2014.55.8437  0.453
2014 Templeton AJ, Diez-Gonzalez L, Ace O, Vera-Badillo F, Seruga B, Jordán J, Amir E, Pandiella A, Ocaña A. Prognostic relevance of receptor tyrosine kinase expression in breast cancer: a meta-analysis. Cancer Treatment Reviews. 40: 1048-55. PMID 25217796 DOI: 10.1016/J.Ctrv.2014.08.003  0.389
2014 Habbous S, Pang V, Xu W, Amir E, Liu G. Human papillomavirus and host genetic polymorphisms in carcinogenesis: a systematic review and meta-analysis. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 61: 220-9. PMID 25174543 DOI: 10.1016/J.Jcv.2014.07.019  0.312
2014 Vera-Badillo FE, Ocana A, Templeton AJ, Tibau A, Amir E, Tannock IF. Raising concern about the American Society of Clinical Oncology conflict of interest policy amendment. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 3197. PMID 25092777 DOI: 10.1200/Jco.2014.56.2447  0.418
2014 Templeton AJ, Pezaro C, Omlin A, McNamara MG, Leibowitz-Amit R, Vera-Badillo FE, Attard G, de Bono JS, Tannock IF, Amir E. Simple prognostic score for metastatic castration-resistant prostate cancer with incorporation of neutrophil-to-lymphocyte ratio. Cancer. 120: 3346-52. PMID 24995769 DOI: 10.1002/Cncr.28890  0.488
2014 Vera-Badillo FE, Napoleone M, Ocana A, Templeton AJ, Seruga B, Al-Mubarak M, AlHashem H, Tannock IF, Amir E. Effect of multifocality and multicentricity on outcome in early stage breast cancer: a systematic review and meta-analysis. Breast Cancer Research and Treatment. 146: 235-44. PMID 24928527 DOI: 10.1200/Jco.2014.32.15_Suppl.546  0.528
2014 Templeton AJ, McNamara MG, Šeruga B, Vera-Badillo FE, Aneja P, Ocaña A, Leibowitz-Amit R, Sonpavde G, Knox JJ, Tran B, Tannock IF, Amir E. Prognostic role of neutrophil-to-lymphocyte ratio in solid tumors: a systematic review and meta-analysis. Journal of the National Cancer Institute. 106: dju124. PMID 24875653 DOI: 10.1093/Jnci/Dju124  0.49
2014 Templeton AJ, Ace O, McNamara MG, Al-Mubarak M, Vera-Badillo FE, Hermanns T, Seruga B, Ocaña A, Tannock IF, Amir E. Prognostic role of platelet to lymphocyte ratio in solid tumors: a systematic review and meta-analysis. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 23: 1204-12. PMID 24793958 DOI: 10.1158/1055-9965.Epi-14-0146  0.484
2014 Erman A, Nugent A, Amir E, Coyte PC. Cost-effectiveness analysis of extended adjuvant endocrine therapy in the treatment of post-menopausal women with hormone receptor positive breast cancer. Breast Cancer Research and Treatment. 145: 267-79. PMID 24771048 DOI: 10.1007/S10549-014-2950-6  0.34
2014 Addison CL, Bouganim N, Hilton J, Vandermeer L, Dent S, Amir E, Hopkins S, Kuchuk I, Segal R, Song X, Gertler S, Mazzarello S, Dranitsaris G, Ooi D, Pond G, et al. A phase II, multicentre trial evaluating the efficacy of de-escalated bisphosphonate therapy in metastatic breast cancer patients at low-risk of skeletal-related events Breast Cancer Research and Treatment. 144: 615-624. PMID 24638849 DOI: 10.1007/S10549-014-2906-X  0.342
2014 McNamara MG, Templeton AJ, Maganti M, Walter T, Horgan AM, McKeever L, Min T, Amir E, Knox JJ. Neutrophil/lymphocyte ratio as a prognostic factor in biliary tract cancer. European Journal of Cancer (Oxford, England : 1990). 50: 1581-9. PMID 24630393 DOI: 10.1016/J.Ejca.2014.02.015  0.365
2014 Al-Mubarak M, Tibau A, Templeton AJ, Cescon DW, Ocana A, Seruga B, Amir E. Extended adjuvant tamoxifen for early breast cancer: a meta-analysis. Plos One. 9: e88238. PMID 24586311 DOI: 10.1200/Jco.2013.31.15_Suppl.539  0.422
2014 Seruga B, Zadnik V, Kuhar CG, Marinko T, Cufer T, Zakotnik B, Zorman D, Ocana A, Amir E. Association of aromatase inhibitors with coronary heart disease in women with early breast cancer. Cancer Investigation. 32: 99-104. PMID 24548302 DOI: 10.3109/07357907.2014.880452  0.369
2014 Horgan AM, Seruga B, Pond GR, Alibhai SM, Amir E, De Wit R, Eisenberger MA, Tannock IF. Tolerability and efficacy of docetaxel in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial. Journal of Geriatric Oncology. 5: 119-26. PMID 24495703 DOI: 10.1016/J.Jgo.2013.12.001  0.491
2014 Ocaña A, Freedman O, Amir E, Seruga B, Pandiella A. Biological insights into effective and antagonistic combinations of targeted agents with chemotherapy in solid tumors. Cancer Metastasis Reviews. 33: 295-307. PMID 24338003 DOI: 10.1007/S10555-013-9451-7  0.33
2014 Vera-Badillo FE, Templeton AJ, de Gouveia P, Diaz-Padilla I, Bedard PL, Al-Mubarak M, Seruga B, Tannock IF, Ocana A, Amir E. Androgen receptor expression and outcomes in early breast cancer: a systematic review and meta-analysis. Journal of the National Cancer Institute. 106: djt319. PMID 24273215 DOI: 10.1093/Jnci/Djt319  0.552
2014 Templeton AJ, Omlin AG, Pezaro CJ, Kheoh TS, Leibowitz-Amit R, Vera-Badillo FE, Tannock I, Attard G, Amir E, De Bono JS. A prognostic score for patients with metastatic castration-resistant prostate cancer treated with abiraterone acetate post chemotherapy. Journal of Clinical Oncology. 32: 70-70. DOI: 10.1200/Jco.2014.32.4_Suppl.70  0.502
2014 Templeton AJ, Amir E, Aneja P, Vera-Badillo FE, Hermanns T, McNamara MG, Heng DYC, Knox JJ. Neutrophil to lymphocyte ratio and response to tyrosine kinase inhibitor therapy in metastatic renal cell carcinoma. Journal of Clinical Oncology. 32: 477-477. DOI: 10.1200/Jco.2014.32.4_Suppl.477  0.313
2014 Vera-Badillo FE, Templeton A, Ocana A, deGouveia P, Aneja P, Knox JJ, Tannock I, Duran I, Escudier BJ, Amir E. Response to systemic therapy in non-clear cell renal cell carcinomas: A systematic review and meta-analysis. Journal of Clinical Oncology. 32: 425-425. DOI: 10.1200/Jco.2014.32.4_Suppl.425  0.501
2014 Niraula S, Amir E, Vera Badillo FE, Seruga B, Ocana A, Tannock I. Absolute risk and cost of management of toxicities of newly approved anticancer drugs: A meta-analysis. Journal of Clinical Oncology. 32: e17556-e17556. DOI: 10.1200/Jco.2014.32.15_Suppl.E17556  0.451
2014 Chan M, Chang M, Gonzalez R, Lategan B, del Barco E, Vera-Badillo FE, Quesada P, Goldstein R, Cruz I, Ocana A, Cruz JJ, Amir E. Clinical outcomes of estrogen receptor (ER)-negative and progesterone receptor (PgR)-positive invasive breast cancer. Journal of Clinical Oncology. 32: 567-567. DOI: 10.1200/Jco.2014.32.15_Suppl.567  0.389
2014 Vera-Badillo FE, Chang M, Kuruzar G, Ocana A, Templeton AJ, Seruga B, Al-Mubarak M, Goldstein R, Bedard PL, Tannock I, Amir E. Association between androgen receptor (AR) expression, Ki-67, and the 21-gene recurrence score in early breast cancer. Journal of Clinical Oncology. 32: 547-547. DOI: 10.1200/Jco.2014.32.15_Suppl.547  0.518
2014 Templeton AJ, Vera-Badillo FE, Mercier F, Sonpavde G, Amir E, Tombal BF, Rosenthal M, Tannock I. Prognostic role of derived neutrophil to lymphocyte ratio (dNLR) in men with metastatic castration resistant prostate cancer (mCRPC) treated in a phase 3 trial (VENICE). Journal of Clinical Oncology. 32: 5047-5047. DOI: 10.1200/Jco.2014.32.15_Suppl.5047  0.522
2014 Thavendiranathan P, Amir E, Bedard P, Crean A, Paul N, Nguyen ET, Wintersperger BJ. Regional myocardial edema detected by T2 mapping is a feature of cardiotoxicity in breast cancer patients receiving sequential therapy with anthracyclines and trastuzumab Journal of Cardiovascular Magnetic Resonance. 16. DOI: 10.1186/1532-429X-16-S1-P273  0.402
2014 Niraula S, Amir E, Seruga B, Vera-Badillo F, Ocana A, Tannock IF. 1386O_Prrisk Of Incremental Toxicities And Associated Costs Of New Anticancer Drugs: A Meta-Analysis Annals of Oncology. 25. DOI: 10.1093/Annonc/Mdu438.55  0.511
2014 Al Hashem H, Al-Mubarak M, Templeton A, Ocana A, Seruga B, Amir E. Impact of Geographic Region on Benefit of Anticancer Agents Evaluated in International Phase III Clinical Trials Annals of Oncology. 25: iv486. DOI: 10.1093/Annonc/Mdu353.2  0.331
2014 Tibau B, Bedard P, Vera-Badillo F, Templeton A, Ocana A, Seruga B, Barnadas A, Amir E. Author Financial Conflicts of Interest (Fcois) in Clinical Practice Guidelines (Cpgs) for Systemic Anti-Cancer Drugs Annals of Oncology. 25: iv486. DOI: 10.1093/Annonc/Mdu353.1  0.39
2014 Puts M, Krzyzanowska M, Amir E, Joshua A, Monette J, Wan-Chow-Wah D, Jang R, Alibhai S. A feasibility trial of geriatric assessment and management for older cancer patients Journal of Geriatric Oncology. 5: S47-S48. DOI: 10.1016/J.Jgo.2014.09.080  0.37
2013 Russell K, Amir E, Paterson A, Josse R, Addison C, Kuchuk I, Clemons M. Does estrogen play a role in response to adjuvant bone-targeted therapies? Journal of Bone Oncology. 2: 167-73. PMID 26909288 DOI: 10.1016/J.Jbo.2013.06.001  0.408
2013 McNamara MG, Walter T, Horgan AM, Amir E, Cleary S, McKeever EL, Min T, Wallace E, Hedley D, Krzyzanowska M, Moore M, Gallinger S, Greig P, Serra S, Dawson LA, et al. Outcome of Adjuvant Therapy in Biliary Tract Cancers. American Journal of Clinical Oncology. PMID 24572429 DOI: 10.1097/Coc.0B013E31829E19Fb  0.38
2013 Manji A, Brana I, Amir E, Tomlinson G, Tannock IF, Bedard PL, Oza A, Siu LL, Razak AR. Evolution of clinical trial design in early drug development: systematic review of expansion cohort use in single-agent phase I cancer trials. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 4260-7. PMID 24127441 DOI: 10.1200/Jco.2012.47.4957  0.54
2013 Templeton AJ, Vera-Badillo FE, Wang L, Attalla M, De Gouveia P, Leibowitz-Amit R, Knox JJ, Moore M, Sridhar SS, Joshua AM, Pond GR, Amir E, Tannock IF. Translating clinical trials to clinical practice: outcomes of men with metastatic castration resistant prostate cancer treated with docetaxel and prednisone in and out of clinical trials. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 24: 2972-7. PMID 24126362 DOI: 10.1093/Annonc/Mdt397  0.515
2013 Ocana A, Amir E, Vera-Badillo F, Seruga B, Tannock IF. Phase III trials of targeted anticancer therapies: redesigning the concept. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4931-40. PMID 23881926 DOI: 10.1158/1078-0432.Ccr-13-1222  0.505
2013 Al-Mubarak M, Sacher AG, Ocana A, Vera-Badillo F, Seruga B, Amir E. Fulvestrant for advanced breast cancer: a meta-analysis. Cancer Treatment Reviews. 39: 753-8. PMID 23764179 DOI: 10.1016/J.Ctrv.2013.03.004  0.441
2013 Bouganim N, Tsvetkova E, Clemons M, Amir E. Evolution of sites of recurrence after early breast cancer over the last 20 years: Implications for patient care and future research Breast Cancer Research and Treatment. 139: 603-606. PMID 23681402 DOI: 10.1007/S10549-013-2561-7  0.421
2013 Diaz-Padilla I, Romero N, Amir E, Matias-Guiu X, Vilar E, Muggia F, Garcia-Donas J. Mismatch repair status and clinical outcome in endometrial cancer: a systematic review and meta-analysis. Critical Reviews in Oncology/Hematology. 88: 154-67. PMID 23562498 DOI: 10.1016/J.Critrevonc.2013.03.002  0.368
2013 Vera-Badillo FE, Al-Mubarak M, Templeton AJ, Amir E. Benefit and harms of new anti-cancer drugs. Current Oncology Reports. 15: 270-5. PMID 23435854 DOI: 10.1007/S11912-013-0303-Y  0.398
2013 Vera-Badillo FE, Shapiro R, Ocana A, Amir E, Tannock IF. Bias in reporting of end points of efficacy and toxicity in randomized, clinical trials for women with breast cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 24: 1238-44. PMID 23303339 DOI: 10.1093/Annonc/Mds636  0.579
2013 Ocana A, Vera-Badillo F, Seruga B, Templeton A, Pandiella A, Amir E. HER3 overexpression and survival in solid tumors: a meta-analysis. Journal of the National Cancer Institute. 105: 266-73. PMID 23221996 DOI: 10.1093/Jnci/Djs501  0.323
2013 Amir E, Freedman O, Carlsson L, Dranitsaris G, Tomlinson G, Laupacis A, Tannock IF, Clemons M. Randomized feasibility study of de-escalated (every 12 wk) versus standard (every 3 to 4 wk) intravenous pamidronate in women with low-risk bone metastases from breast cancer. American Journal of Clinical Oncology. 36: 436-42. PMID 22781385 DOI: 10.1097/Coc.0B013E3182568F7A  0.48
2013 Ocaña A, Amir E, Seruga B, Martin M, Pandiella A. The evolving landscape of protein kinases in breast cancer: clinical implications. Cancer Treatment Reviews. 39: 68-76. PMID 22703833 DOI: 10.1016/J.Ctrv.2012.05.004  0.413
2013 Al-Mubarak M, Templeton A, Vera-Badillo F, Ocana A, Seruga B, Amir E. Abstract P6-06-12: Prognostic significance of pretreatment neutrophil/-lymphocyte ratio in breast cancer: A meta-analysis Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P6-06-12  0.434
2013 Abdel-Qadir H, Fischer H, Fu L, Amir E, Harvey P, Lee D, Rochon P, Anderson G. The Risk of Ischemic Heart Disease With Adjuvant Endocrine Therapy in Postmenopausal Women With Early Stage Breast Cancer Canadian Journal of Cardiology. 29: S348. DOI: 10.1016/J.Cjca.2013.07.594  0.38
2012 Mourskaia AA, Amir E, Dong Z, Tiedemann K, Cory S, Omeroglu A, Bertos N, Ouellet V, Clemons M, Scheffer GL, Park M, Hallett M, Komarova SV, Siegel PM. ABCC5 supports osteoclast formation and promotes breast cancer metastasis to bone. Breast Cancer Research : Bcr. 14: R149. PMID 23174366 DOI: 10.1186/Bcr3361  0.402
2012 Amir E, Bedard PL, Ocaña A, Seruga B. Benefits and harms of detecting clinically occult breast cancer. Journal of the National Cancer Institute. 104: 1542-7. PMID 22988040 DOI: 10.1093/Jnci/Djs394  0.417
2012 Templeton A, Ocaña A, Seruga B, Vera-Badillo F, Carlsson L, Bedard P, Amir E. Management of small HER2 overexpressing tumours. Breast Cancer Research and Treatment. 136: 289-93. PMID 22956007 DOI: 10.1007/S10549-012-2236-9  0.432
2012 Niraula S, Seruga B, Ocana A, Shao T, Goldstein R, Tannock IF, Amir E. The price we pay for progress: a meta-analysis of harms of newly approved anticancer drugs. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 3012-9. PMID 22802313 DOI: 10.1200/Jco.2011.40.3824  0.495
2012 Fralick M, Hilton JF, Bouganim N, Clemons M, Amir E. Dual blockade of HER2 - twice as good or twice as toxic? Clinical Oncology (Royal College of Radiologists (Great Britain)). 24: 593-603. PMID 22748560 DOI: 10.1016/J.Clon.2012.05.009  0.401
2012 Seruga B, Pond GR, Hertz PC, Amir E, Ocana A, Tannock IF. Comparison of absolute benefits of anticancer therapies determined by snapshot and area methods. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 23: 2977-82. PMID 22734009 DOI: 10.1093/Annonc/Mds174  0.501
2012 Eng L, Azad AK, Habbous S, Pang V, Xu W, Maitland-van der Zee AH, Savas S, Mackay HJ, Amir E, Liu G. Vascular endothelial growth factor pathway polymorphisms as prognostic and pharmacogenetic factors in cancer: a systematic review and meta-analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 4526-37. PMID 22733538 DOI: 10.1158/1078-0432.Ccr-12-1315  0.355
2012 Tabariès S, Dupuy F, Dong Z, Monast A, Annis MG, Spicer J, Ferri LE, Omeroglu A, Basik M, Amir E, Clemons M, Siegel PM. Claudin-2 promotes breast cancer liver metastasis by facilitating tumor cell interactions with hepatocytes. Molecular and Cellular Biology. 32: 2979-91. PMID 22645303 DOI: 10.1128/Mcb.00299-12  0.392
2012 Horgan AM, Amir E, Walter T, Knox JJ. Adjuvant therapy in the treatment of biliary tract cancer: a systematic review and meta-analysis. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 1934-40. PMID 22529261 DOI: 10.1200/Jco.2011.40.5381  0.396
2012 Amir E, Cecchini RS, Ganz PA, Costantino JP, Beddows S, Hood N, Goodwin PJ. 25-Hydroxy vitamin-D, obesity, and associated variables as predictors of breast cancer risk and tamoxifen benefit in NSABP-P1. Breast Cancer Research and Treatment. 133: 1077-88. PMID 22415479 DOI: 10.1007/S10549-012-2012-X  0.399
2012 Ocana A, Amir E, Yeung C, Seruga B, Tannock IF. How valid are claims for synergy in published clinical studies? Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 23: 2161-6. PMID 22314859 DOI: 10.1093/Annonc/Mdr608  0.477
2012 Amir E, Clemons M, Purdie CA, Miller N, Quinlan P, Geddie W, Coleman RE, Freedman OC, Jordan LB, Thompson AM. Tissue confirmation of disease recurrence in breast cancer patients: pooled analysis of multi-centre, multi-disciplinary prospective studies. Cancer Treatment Reviews. 38: 708-14. PMID 22178456 DOI: 10.1016/J.Ctrv.2011.11.006  0.421
2012 Amir E, Miller N, Geddie W, Freedman O, Kassam F, Simmons C, Oldfield M, Dranitsaris G, Tomlinson G, Laupacis A, Tannock IF, Clemons M. Prospective study evaluating the impact of tissue confirmation of metastatic disease in patients with breast cancer Journal of Clinical Oncology. 30: 587-592. PMID 22124102 DOI: 10.1200/Jco.2010.33.5232  0.499
2012 Amir E, Seruga B, Kwong R, Tannock IF, Ocaña A. Poor correlation between progression-free and overall survival in modern clinical trials: are composite endpoints the answer? European Journal of Cancer (Oxford, England : 1990). 48: 385-8. PMID 22115991 DOI: 10.1016/J.Ejca.2011.10.028  0.5
2012 Vera Badillo FE, Shapiro R, Ocana A, Amir E, Tannock I. Bias in reporting of endpoints of efficacy and toxicity in randomized clinical trials (RCTs) for women with breast cancer (BC). Journal of Clinical Oncology. 30: 6043-6043. DOI: 10.1200/Jco.2012.30.15_Suppl.6043  0.521
2012 Seruga B, Zadnik V, Grasic Kuhar C, Marinko T, Zorman D, Cufer T, Zakotnik B, Ocana A, Amir E. Aromatase inhibitors and cardiac outcomes in women undergoing cardiac angiography after early breast cancer. Journal of Clinical Oncology. 30: 558-558. DOI: 10.1200/Jco.2012.30.15_Suppl.558  0.384
2012 Bouganim N, Vandermeer L, Kuchuk I, Dent S, Hopkins S, Song X, Robbins D, Spencer P, Mazzarello S, Hilton J, Amir E, Dranitsaris G, Addison C, Mallick R, Clemons M. Abstract P3-13-05: Evaluating efficacy of de-escalated bisphosphonate therapy in metastatic breast cancer patients at low-risk of skeletal related events. TRIUMPH: A pragmatic multicentre trial. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P3-13-05  0.37
2012 Sahebjam S, Diaz-Padilla I, Ocana A, Seruga B, Amir E. Abstract P2-10-23: Lymphovascular Invasion (LVI) and Overall Survival in Node-negative and Node-positive Breast Cancer Patients: A Meta-analysis. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P2-10-23  0.383
2012 Addison C, Zhao H, Mazzarello S, Mallick R, Amir E, Tannock I, Clemons M. Abstract P2-05-12: Effects of de-escalated bisphosphonate therapy on bone turnover or metastasis markers and their correlation with risk of skeletal related events – A biomarker analysis in conjunction with the REFORM study. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P2-05-12  0.462
2012 Manji A, Garcia IB, Amir E, Tannock IF, Bedard P, Oza AM, Siu L, Razak ARA. Evolution of Clinical Trial Design in Early Drug Development: The Use of Expansion Cohorts (ECS) in Phase I Cancer Trials (PITS) Annals of Oncology. 23. DOI: 10.1016/S0923-7534(20)33013-1  0.515
2012 Ocana A, Badillo FV, Seruga B, Pandiella A, Amir E. Meta-Analysis of HER3 Expression and Prognosis in Solid Tumors Annals of Oncology. 23. DOI: 10.1016/S0923-7534(20)32799-X  0.384
2011 Bouganim N, Hilton JF, Vandermeer L, Hopkins S, Robbins D, Amir E, Dent S, Milano C, Freedman OC, Dent RA, Dranitsaris G, Clemons MJ. A multicenter study assessing 12-weekly intravenous bisphosphonate therapy in women with low-risk bone metastases from breast cancer: The TRIUMPH trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: TPS242. PMID 28023584 DOI: 10.1200/Jco.2011.29.15_Suppl.Tps242  0.412
2011 Sullivan R, Peppercorn J, Sikora K, Zalcberg J, Meropol NJ, Amir E, Khayat D, Boyle P, Autier P, Tannock IF, Fojo T, Siderov J, Williamson S, Camporesi S, McVie JG, et al. Delivering affordable cancer care in high-income countries. The Lancet. Oncology. 12: 933-80. PMID 21958503 DOI: 10.1016/S1470-2045(11)70141-3  0.508
2011 Amir E, Seruga B, Niraula S, Carlsson L, Ocaña A. Toxicity of adjuvant endocrine therapy in postmenopausal breast cancer patients: a systematic review and meta-analysis. Journal of the National Cancer Institute. 103: 1299-309. PMID 21743022 DOI: 10.1093/jnci/djr242  0.323
2011 Amir E, Seruga B, Martinez-Lopez J, Kwong R, Pandiella A, Tannock IF, Ocaña A. Oncogenic targets, magnitude of benefit, and market pricing of antineoplastic drugs. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2543-9. PMID 21606435 DOI: 10.1200/Jco.2011.35.2393  0.365
2011 Freedman O, Amir E, Zimmermann C, Clemons M. Filling in the gaps: reporting of concurrent supportive care therapies in breast cancer chemotherapy trials. Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer. 19: 315-22. PMID 21203780 DOI: 10.1007/s00520-010-1069-5  0.309
2011 Dranitsaris G, Truter I, Lubbe MS, Amir E, Evans W. Advances in cancer therapeutics and patient access to new drugs. Pharmacoeconomics. 29: 213-24. PMID 21184619 DOI: 10.2165/11584210-000000000-00000  0.4
2011 Ocaña A, Amir E, Vera F, Eisenhauer EA, Tannock IF. Addition of bevacizumab to chemotherapy for treatment of solid tumors: similar results but different conclusions. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 254-6. PMID 21149670 DOI: 10.1200/Jco.2010.32.0275  0.49
2011 Saibil S, Fitzgerald B, Freedman OC, Amir E, Napolskikh J, Salvo N, Dranitsaris G, Clemons M. Incidence of taxane-induced pain and distress in patients receiving chemotherapy for early-stage breast cancer: a retrospective, outcomes-based survey. Current Oncology (Toronto, Ont.). 17: 42-7. PMID 20697513 DOI: 10.3747/CO.V17I4.562  0.325
2011 Florescu A, Amir E, Bouganim N, Clemons M. Immune therapy for breast cancer in 2010-hype or hope? Current Oncology. 18. DOI: 10.3747/Co.V18I1.623  0.41
2011 Niraula S, Amir E, Ocana A, Seruga B, Tannock I. The balance between benefits and harms of molecular targeted agents. Journal of Clinical Oncology. 29: 6030-6030. DOI: 10.1200/Jco.2011.29.15_Suppl.6030  0.466
2011 Seruga B, Horgan AM, Pond GR, Alibhai SMH, Amir E, De Wit R, Eisenberger MA, Tannock I. Tolerability and efficacy of chemotherapy in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial. Journal of Clinical Oncology. 29: 4530-4530. DOI: 10.1200/Jco.2011.29.15_Suppl.4530  0.493
2011 Horgan AM, Amir E, Walter T, Knox JJ. Adjuvant therapy in the treatment of biliary tract cancer (BTC): A systematic review and meta-analysis. Journal of Clinical Oncology. 29: 4050-4050. DOI: 10.1200/Jco.2011.29.15_Suppl.4050  0.376
2011 Amir E, Cecchini RS, Ganz PA, Costantino JP, Beddows S, Hood N, Goodwin PJ. 25-hydroxy vitamin D (VitD) and associated variables as predictors of breast cancer (BC) risk and tamoxifen benefit in NSABP-P1. Journal of Clinical Oncology. 29: 1528-1528. DOI: 10.1200/Jco.2011.29.15_Suppl.1528  0.324
2011 Amir E, Freedman O, Carlsson L, Usmani T, Lee E, Dranitsaris G, Clemons M. P4-16-08: Pilot Randomized Trial of De-Escalated (q12 Weekly) Versus Standard (q3-4 Weekly) Intravenous Bisphosphonates in Women with Low-Risk Bone Metastases from Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-16-08  0.366
2011 Bouganim N, Clemons M, Amir E. P4-11-08: Changes in the Distribution of Loco-Regional and Distant Breast Cancer Recurrences over the Last 20 Years: Implications for Patient Care and Future Research. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-11-08  0.364
2011 Amir E, Carlsson L, Seruga B, Ocana A, Goodwin P. P4-10-02: A Meta-Analysis of the Association of Blood Levels of Vitamin-D and the Risk of Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-10-02  0.392
2011 Amir E, Seruga B, Ocaña A, Carlsson L, Bedard P. P2-12-07: Pooled Analysis of Outcomes of T1a/bN0, HER2−Amplified Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P2-12-07  0.415
2011 Bouganim N, Hilton J, Vandermeer L, Hopkins S, Spencer P, Robbins D, Amir E, Dent S, Milano C, Ooi D, Dranitsaris G, Clemons M. OT1-01-02: A Multicentre Study Assessing 12-Weekly Intravenous Bisphosphonate Therapy in Women with Low Risk Bone Metastases from Breast Cancer – The TRIUMPH Trial. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Ot1-01-02  0.426
2011 Sullivan R, Peppercorn J, Sikora K, Zalcberg J, Meropol N, Amir E, Khayat D, Boyle P, Tannock I, Fojo T. Delivering Affordable Cancer Care in High-income Countries: a Lancet Oncology Commission European Journal of Cancer. 47: 6. DOI: 10.1016/S0959-8049(11)70107-1  0.472
2010 Amir E, Freedman O, Allen L, Colgan T, Clemons M. Defining ovarian failure in amenorrheic young breast cancer patients. Breast (Edinburgh, Scotland). 19: 545-8. PMID 20615705 DOI: 10.1016/j.breast.2010.06.003  0.331
2010 Seruga B, Amir E. Cytochrome P450 2D6 and outcomes of adjuvant tamoxifen therapy: results of a meta-analysis. Breast Cancer Research and Treatment. 122: 609-17. PMID 20454926 DOI: 10.1007/s10549-010-0902-3  0.314
2010 Amir E, Freedman OC, Seruga B, Evans DG. Assessing women at high risk of breast cancer: a review of risk assessment models. Journal of the National Cancer Institute. 102: 680-91. PMID 20427433 DOI: 10.1093/Jnci/Djq088  0.364
2010 Amir E, Seruga B, Serrano R, Ocana A. Targeting DNA repair in breast cancer: a clinical and translational update. Cancer Treatment Reviews. 36: 557-65. PMID 20385443 DOI: 10.1016/J.Ctrv.2010.03.006  0.36
2010 Amir E, Ocaña A, Seruga B, Josse R, Clemons M. Medical oncology: Zoledronic acid for breast cancer therapy-induced bone loss. Nature Reviews. Clinical Oncology. 7: 187-8. PMID 20354540 DOI: 10.1038/Nrclinonc.2010.19  0.383
2010 Amir E, Ocana A, Freedman O, Clemons M, Seruga B. Chemotherapy: dose-dense treatment for triple-negative breast cancer. Nature Reviews. Clinical Oncology. 7: 79-80. PMID 20118978 DOI: 10.1038/Nrclinonc.2009.231  0.41
2010 Amir E, Ocaña A, Seruga B, Freedman O, Clemons M. Lapatinib and HER2 status: results of a meta-analysis of randomized phase III trials in metastatic breast cancer. Cancer Treatment Reviews. 36: 410-5. PMID 20100635 DOI: 10.1016/J.Ctrv.2009.12.012  0.412
2010 Amir E, Simmons CE, Freedman OC, Dranitsaris G, Cole DE, Vieth R, Ooi WS, Clemons M. A phase 2 trial exploring the effects of high-dose (10,000 IU/day) vitamin D(3) in breast cancer patients with bone metastases. Cancer. 116: 284-91. PMID 19918922 DOI: 10.1002/Cncr.24749  0.322
2010 Freedman OC, Amir E, Hanna W, Kahn H, O'Malley F, Dranitsaris G, Cole DE, Verma S, Folkerd E, Dowsett M, Clemons M. A randomized trial exploring the biomarker effects of neoadjuvant sequential treatment with exemestane and anastrozole in post-menopausal women with hormone receptor-positive breast cancer. Breast Cancer Research and Treatment. 119: 155-61. PMID 19731013 DOI: 10.1007/S10549-009-0523-X  0.427
2010 Bouganim N, Amir E, Clemons M. Bonus 5: 5th annual bone and the oncologist new updates Current Oncology. 17: 113-118. DOI: 10.3747/Co.V17I4.691  0.334
2010 Simmons CE, Amir E, Lee E, Hogeveen S, Dent RA, Goodwin PJ, Clemons M. Suppression of bone turnover following treatment with zoledronic acid in patients wtih metastatic breast cancer: Duration of effect—The SuBDuE study. Journal of Clinical Oncology. 28: TPS121-TPS121. DOI: 10.1200/Jco.2010.28.15_Suppl.Tps121  0.3
2010 Amir E, Clemons M, Freedman OC, Miller N, Coleman RE, Purdie C, Jordan L, Quinlan P, Thompson AM. Tissue confirmation of disease recurrence in patients with breast cancer: Pooled analysis of two large prospective studies. Journal of Clinical Oncology. 28: 1007-1007. DOI: 10.1200/Jco.2010.28.15_Suppl.1007  0.378
2010 Amir E, Ocaña A, Niraula S, Carlsson L, Seruga B. Abstract S2-7: Toxicity of Adjuvant Endocrine Therapy in Postmenopausal Breast Cancer Patients Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-S2-7  0.431
2010 Amir E, Miller N, Geddie W, Maung H, Freedman O, Oldfield M, Napolskikh J, Kassam F, Simmons C, Clemons M. Abstract PD10-05: Do the Results of Metastatic Breast Tumour Biopsies Affect Patient Survival Outcomes? Results from a Large Prospective Trial Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-Pd10-05  0.408
2010 Amir E, Ouellet V, Mourskaia A, Tiedemann K, Fong J, Tran-Tanh D, Clemons M, Perbal B, Komorova S, Siegel P. Abstract P6-07-01: CCN3 Impairs Osteoblasts and Stimulates Osteoclast Differentiation To Favor Breast Cancer Metastasis to Bone Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P6-07-01  0.372
2010 Freedman O, Amir E, Cheung A, Hu H, Lee E, Dranitsaris G, Clemons M. Abstract P1-13-08: A Cross-Sectional Study Evaluating Bone Quantity and Quality in Women with Bone Metastases from Breast Cancer Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P1-13-08  0.329
2009 Amir E, Freedman OC, Dranitsaris G, Napolskikh J, Chia S, Petrella T, Dent S, Kumar R, Fralick M, Clemons M. Developing a prediction model for benefit from fulvestrant in heavily pretreated metastatic breast cancer (MBC) patients. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 1041. PMID 27961124 DOI: 10.1200/Jco.2009.27.15_Suppl.1041  0.401
2009 Broom RJ, Amir E, Cawthorn T, Freedman O, Gianfelice D, Barth D, Galica J, Wang D, Done SJ, Clemons M. Gene expression differences between disseminated tumor cells and tumor cells from overt bone metastases in patients with metastatic breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 1040. PMID 27961118 DOI: 10.1200/Jco.2009.27.15_Suppl.1040  0.314
2009 Seruga B, Amir E, Tannock I. Treatment of lung cancer. The New England Journal of Medicine. 361: 2485; author reply 2. PMID 20050212 DOI: 10.1056/NEJMc0909634  0.4
2009 Amir E, Seruga B, Freedman O, Clemons M. Amenorrhoea, menopause, and endocrine therapy for breast cancer. Bmj (Clinical Research Ed.). 339: b4261. PMID 19959583 DOI: 10.1136/Bmj.B4261  0.413
2009 Amir E, Tannock IF. Prostate cancer: Androgen deprivation therapy and bone loss. Nature Reviews. Urology. 6: 642-4. PMID 19956194 DOI: 10.1038/Nrurol.2009.218  0.472
2009 Amir E, Clemons M. Should a biopsy be recommended to confirm metastatic disease in women with breast cancer? The Lancet. Oncology. 10: 933-5. PMID 19796747 DOI: 10.1016/S1470-2045(09)70295-5  0.39
2009 Ocaña A, Amir E. Irreversible pan-ErbB tyrosine kinase inhibitors and breast cancer: current status and future directions. Cancer Treatment Reviews. 35: 685-91. PMID 19733440 DOI: 10.1016/J.Ctrv.2009.08.001  0.398
2009 Cawthorn TR, Amir E, Broom R, Freedman O, Gianfelice D, Barth D, Wang D, Holen I, Done SJ, Clemons M. Mechanisms and pathways of bone metastasis: challenges and pitfalls of performing molecular research on patient samples. Clinical & Experimental Metastasis. 26: 935-43. PMID 19697143 DOI: 10.1007/S10585-009-9284-5  0.321
2009 Freedman O, Amir E, Dranitsaris G, Napolskikh J, Kumar R, Fralick M, Chia S, Petrella T, Dent S, Tonkin K, Ahmad I, Rayson D, Clemons M. Predicting benefit from fulvestrant in pretreated metastatic breast cancer patients. Breast Cancer Research and Treatment. 118: 377-83. PMID 19551499 DOI: 10.1007/S10549-009-0452-8  0.415
2009 Freedman OC, Amir E, Clemons MJ. Adjuvant bisphosphonate therapy for breast cancer patients: Standard of care or future direction? Critical Reviews in Oncology/Hematology. 72: 56-64. PMID 19307138 DOI: 10.1016/J.Critrevonc.2009.03.001  0.46
2009 Amir E, Whyne C, Freedman OC, Fralick M, Kumar R, Hardisty M, Clemons M. Radiological changes following second-line zoledronic acid treatment in breast cancer patients with bone metastases Clinical and Experimental Metastasis. 26: 479-484. PMID 19266291 DOI: 10.1007/S10585-009-9247-X  0.317
2009 Amir E, Seruga B, Freedman O, Tannock I. Lapatinib plus paclitaxel as first-line therapy for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: inappropriate conclusions from a company-sponsored study? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 1919; author reply 1. PMID 19255302 DOI: 10.1200/Jco.2008.21.2951  0.545
2009 Freedman O, Amir E, Dranitsaris G, Dowsett M, Cole D, Kahn H, O'Malley F, Verma S, Clemons M. A randomized, phase III trial exploring the effects of neoadjuvant sequential treatment with steroidal (exemestane) and nonsteroidal (anastrozole) aromatase inhibitors on biomarkers in postmenopausal women with hormone receptor-positive locally advanced breast cancer Breast Cancer Research. 11. DOI: 10.1186/Bcr2316  0.463
2009 Amir E, Freedman O, Simmons C, Miller N, Geddie W, DeBorja A, Maung H, Gianfelice D, Murphy K, Clemons M. Biopsy confirmation of metastatic breast cancer: interim results of a prospective biopsy study Breast Cancer Research. 11. DOI: 10.1186/Bcr2314  0.411
2009 Amir E, Freedman O, Chia S, Petrella T, Dent S, Tonkin K, Ahmad I, Rayson D, Dranitsaris G, Clemons M. Developing a prediction model for benefit from fulvestrant in heavily pretreated metastatic breast cancer patients Breast Cancer Research. 11. DOI: 10.1186/Bcr2312  0.432
2009 Amir E, Broom R, Freedman O, Ooi W, Done S, Gianfelice D, Barth D, Kahn H, Clemons M. Discordance between hormone receptor profile of primary breast cancer and metastatic bone disease: should bone marrow biopsy be considered a standard of care? Breast Cancer Research. 11. DOI: 10.1186/Bcr2310  0.341
2009 Amir E, Freedman O, Simmons C, Miller N, Geddie W, Dranitsaris G, Maung H, Napolskikh J, Lax M, Clemons M. Biopsy Confirmation of Metastatic Disease in Breast Cancer: Results from a Large Prospective Study. Cancer Research. 69: 2023-2023. DOI: 10.1158/0008-5472.Sabcs-09-2023  0.37
2009 Freedman O, Amir E, Dranitsaris G, Dowsett M, Cole D, Hanna W, O'Malley F, Folkerd E, Verma S, Clemons M. 5027 A randomized, phase III trial exploring the effects of neoadjuvant sequential treatment with steroidal (exemestane) and non-steroidal (anastrozole) aromatase inhibitors on biomarkers in post-menopausal women with hormone receptor positive locally advanced breast cancer (LABC) European Journal of Cancer Supplements. 7: 269. DOI: 10.1016/S1359-6349(09)70919-X  0.409
2008 Amir E, Ooi WS, Simmons C, Kahn H, Christakis M, Popovic S, Kalina M, Chesney A, Singh G, Clemons M. Discordance between receptor status in primary and metastatic breast cancer: an exploratory study of bone and bone marrow biopsies. Clinical Oncology (Royal College of Radiologists (Great Britain)). 20: 763-8. PMID 18824337 DOI: 10.1016/J.Clon.2008.08.005  0.35
2008 Al-Husaini H, Amir E, Fitzgerald B, Wright F, Dent R, Fralick J, Clemons M. Prevalence of overt metastases in locally advanced breast cancer. Clinical Oncology (Royal College of Radiologists (Great Britain)). 20: 340-4. PMID 18420394 DOI: 10.1016/j.clon.2008.03.006  0.302
Show low-probability matches.