Year |
Citation |
Score |
2024 |
Aquino AF, Runa F, Shoma JF, Todd A, Wallace M, de Barros NR, Kelber JA. Multidimensional screening of pancreatic cancer spheroids reveals vulnerabilities in mitotic and cell-matrix adhesion signaling that associate with metastatic progression and decreased patient survival. Biochemical and Biophysical Research Communications. 703: 149575. PMID 38382357 DOI: 10.1016/j.bbrc.2024.149575 |
0.693 |
|
2023 |
de Barros NR, Gomez A, Ermis M, Falcone N, Haghniaz R, Young P, Gao Y, Aquino AF, Li S, Niu S, Chen R, Huang S, Zhu Y, Eliahoo P, Sun A, ... ... Kelber J, et al. Gelatin methacryloyl and laponite bioink for 3D bioprinted organotypic tumor modeling. Biofabrication. PMID 37348491 DOI: 10.1088/1758-5090/ace0db |
0.348 |
|
2023 |
Geller C, Maddela J, Tuplano R, Runa F, Adamian Y, Güth R, Soto GO, Tomaneng L, Cantor J, Kelber JA. Fibronectin, DHPS and SLC3A2 Signaling Cooperate to Control Tumor Spheroid Growth, Subcellular eIF5A1/2 Distribution and CDK4/6 Inhibitor Resistance. Biorxiv : the Preprint Server For Biology. PMID 37090582 DOI: 10.1101/2023.04.13.536765 |
0.868 |
|
2021 |
Hamalian S, Güth R, Runa F, Sanchez F, Vickers E, Agajanian M, Molnar J, Nguyen T, Gamez J, Humphries JD, Nayak A, Humphries MJ, Tchou J, Zervantonakis IK, Kelber JA. A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for antiapoptotic and stress signaling markers. Oncogene. PMID 34239043 DOI: 10.1038/s41388-021-01906-2 |
0.843 |
|
2020 |
Conner C, Lager TW, Guldner IH, Wu MZ, Hishida Y, Hishida T, Ruiz S, Yamasaki AE, Gilson RC, Belmonte JCI, Gray PC, Kelber JA, Zhang S, Panopoulos AD. Cell surface GRP78 promotes stemness in normal and neoplastic cells. Scientific Reports. 10: 3474. PMID 32103065 DOI: 10.1038/S41598-020-60269-Y |
0.632 |
|
2019 |
Güth R, Adamian Y, Geller C, Molnar J, Maddela J, Kutscher L, Bhakta K, Meade K, Kim SL, Agajanian M, Kelber JA. DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in TP53. Biochemical and Biophysical Research Communications. PMID 31558321 DOI: 10.1016/J.Bbrc.2019.09.075 |
0.836 |
|
2019 |
Meade KJ, Sanchez F, Aguayo A, Nadales N, Hamalian SG, Uhlendorf TL, Banner LR, Kelber JA. Secretomes from metastatic breast cancer cells, enriched for a prognostically unfavorable LCN2 axis, induce anti-inflammatory MSC actions and a tumor-supportive premetastatic lung. Oncotarget. 10: 3027-3039. PMID 31105883 DOI: 10.18632/Oncotarget.26903 |
0.827 |
|
2019 |
Sanchez F, Meade K, Aguayo A, Nadeles N, Hamalian S, Uhlendorf T, Banner L, Kelber JA. Abstract LB-129: Metastatic breast cancer cells promote anti-inflammatory MSC actions and release Lipocalin 2 to induce a tumor-supportive premetastatic lung microenvironment Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Lb-129 |
0.853 |
|
2018 |
Hoover M, Runa F, Booker E, Diedrich JK, Duell E, Williams B, Arellano-Garcia C, Uhlendorf T, La Kim S, Fischer W, Moresco J, Gray PC, Kelber JA. Identification of myosin II as a cripto binding protein and regulator of cripto function in stem cells and tissue regeneration. Biochemical and Biophysical Research Communications. PMID 30579599 DOI: 10.1016/J.Bbrc.2018.12.059 |
0.645 |
|
2018 |
Guth R, Kutscher L, Adamian Y, Geller C, Bahkta K, Meade K, Kelber JA. Abstract 4998: Targeting DHPS to abrogate TGFβ-induced metastasis in breast cancer Cancer Research. 78: 4998-4998. DOI: 10.1158/1538-7445.Am2018-4998 |
0.869 |
|
2018 |
Hamalian S, Güth R, Zervantonakis I, Duell E, Lin J, Shisgal P, Molnar J, Geller C, Agajanian M, Tchou J, Sorger PK, Brugge JS, Kelber JA. Abstract 2140: Mesenchymal stromal cells expressing a PEAK1/Cripto axis sustain pro-survival NF-κB signaling in adjacent tumor cells to promote disease progression and therapy resistance Cancer Research. 78: 2140-2140. DOI: 10.1158/1538-7445.Am2018-2140 |
0.812 |
|
2018 |
Lager TW, Conner HC, Guldner IH, Wu MZ, Hishida Y, Hishida T, Ruiz S, Yamasaki AE, Belmonte JCI, Gray PC, Kelber JA, Zhang S, Panopoulos AD. Abstract 1990: Aberrant cell surface expression of GRP78 in breast cancer cells marks a stem-like population that has increased metastatic potential in vivo Cancer Research. 78: 1990-1990. DOI: 10.1158/1538-7445.Am2018-1990 |
0.642 |
|
2017 |
Runa F, Hamalian S, Meade K, Shisgal P, Gray PC, Kelber JA. Tumor microenvironment heterogeneity: challenges and opportunities. Current Molecular Biology Reports. 3: 218-229. PMID 29430386 DOI: 10.1007/s40610-017-0073-7 |
0.804 |
|
2017 |
Gharibi A, La Kim S, Molnar J, Brambilla D, Adamian Y, Hoover M, Hong J, Lin J, Wolfenden L, Kelber JA. ITGA1 is a pre-malignant biomarker that promotes therapy resistance and metastatic potential in pancreatic cancer. Scientific Reports. 7: 10060. PMID 28855593 DOI: 10.1038/S41598-017-09946-Z |
0.825 |
|
2017 |
Zoni E, Chen L, Karkampouna S, Granchi Z, Verhoef EI, La Manna F, Kelber J, Pelger RC, Henry MD, Snaar-Jagalska E, van Leenders GJ, Beimers L, Kloen P, Gray PC, van der Pluijm G, et al. CRIPTO and its signaling partner GRP78 drive the metastatic phenotype in human osteotropic prostate cancer. Oncogene. PMID 28394345 DOI: 10.1038/Onc.2017.87 |
0.513 |
|
2017 |
Strnadel J, Choi S, Fujimura K, Wang H, Zhang W, Wyse M, Wright T, Gross E, Peinado C, Park HW, Bui J, Kelber J, Bouvet M, Guan KL, Klemke RL. eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth. Cancer Research. PMID 28381547 DOI: 10.1158/0008-5472.Can-16-2594 |
0.738 |
|
2017 |
Kim SL, Gharibi A, Molnar J, Brambilla D, Adamian Y, Hoover M, Lin J, Hong J, Kelber JA. Abstract LB-149: ITGA1 marks pre-malignant pancreatic lesions and drives stem-like cell survival and TGFβ/collagen-induced therapy resistance and metastasis in pancreatic cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-149 |
0.818 |
|
2016 |
Runa F, Adamian Y, Kelber JA. Ascending the PEAK1 toward targeting TGFβ during cancer progression: Recent advances and future perspectives. Cancer Cell & Microenvironment. 3. PMID 29392163 DOI: 10.14800/Ccm.1162 |
0.865 |
|
2016 |
Hoover M, Adamian Y, Brown M, Maawy A, Chang A, Lee J, Gharibi A, Katz MH, Fleming J, Hoffman RM, Bouvet M, Doebler R, Kelber JA. A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts. Oncotarget. PMID 27602776 DOI: 10.18632/Oncotarget.11809 |
0.784 |
|
2016 |
Gharibi A, Adamian Y, Kelber JA. Cellular and molecular aspects of pancreatic cancer. Acta Histochemica. 118: 305-16. PMID 26868366 DOI: 10.1016/J.Acthis.2016.01.009 |
0.808 |
|
2016 |
Hoover M, Adamian Y, Brown M, Maawy AA, Hoffman R, Bouvet M, Doebler R, Kelber JA. Abstract LB-263: Analysis of microenvironment effects on pancreatic cancer biomarker expression using a novel method for FFPE RNA extraction Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-263 |
0.82 |
|
2016 |
Gharibi A, Kim SL, Brambilla D, Adamian Y, Hoover M, Lin J, Agajanian M, Wolfenden L, Kelber JA. Abstract 4426: The PEAK1/ZEB1/ITGA1 pathway mediates survival, stemness and TGFbeta-induced EMT in pancreatic cancer Cancer Research. 76: 4426-4426. DOI: 10.1158/1538-7445.Am2016-4426 |
0.843 |
|
2015 |
Agajanian M, Runa F, Kelber JA. Identification of a PEAK1/ZEB1 signaling axis during TGFβ/fibronectin-induced EMT in breast cancer. Biochemical and Biophysical Research Communications. 465: 606-12. PMID 26297948 DOI: 10.1016/J.Bbrc.2015.08.071 |
0.87 |
|
2015 |
Agajanian M, Campeau A, Hoover M, Hou A, Brambilla D, Kim SL, Klemke RL, Kelber JA. PEAK1 Acts as a Molecular Switch to Regulate Context-Dependent TGFβ Responses in Breast Cancer. Plos One. 10: e0135748. PMID 26267863 DOI: 10.1371/Journal.Pone.0135748 |
0.864 |
|
2015 |
Agajanian M, Runa F, Kelber JA. Identification of a PEAK1/ZEB1 signaling axis during TGFβ/fibronectin-induced EMT in breast cancer Biochemical and Biophysical Research Communications. DOI: 10.1016/j.bbrc.2015.08.071 |
0.836 |
|
2015 |
Gharibi A, Adamian Y, Kelber JA. Cellular and molecular aspects of pancreatic cancer Acta Histochemica. DOI: 10.1016/j.acthis.2016.01.009 |
0.813 |
|
2014 |
Fujimura K, Wright T, Strnadel J, Kaushal S, Metildi C, Lowy AM, Bouvet M, Kelber JA, Klemke RL. A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic cancer. Cancer Research. 74: 6671-81. PMID 25261239 DOI: 10.1158/0008-5472.Can-14-1031 |
0.731 |
|
2014 |
Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl GM, Gray PC. CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo. Stem Cell Reports. 2: 427-39. PMID 24749068 DOI: 10.1016/J.Stemcr.2014.02.010 |
0.686 |
|
2014 |
Choi S, Kelber J, Jiang X, Strnadel J, Fujimura K, Pasillas M, Coppinger J, Klemke R. Procedures for the biochemical enrichment and proteomic analysis of the cytoskeletome. Analytical Biochemistry. 446: 102-7. PMID 24161902 DOI: 10.1016/J.Ab.2013.10.025 |
0.593 |
|
2014 |
Fujimura K, Wright T, Strnadel J, Kelber J, Kaushal S, Metildi C, Lowy A, Bouvet M, Klemke R. Abstract LB-303: A hypusine-eIF5A-PEAK1 switch regulates the pathogenesis of pancreatic ductal adenocarcinoma Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-303 |
0.726 |
|
2014 |
Spike BT, Kelber JA, Booker E, Kalathur M, Rodewald R, Lipianskaya J, La J, He M, Wright T, Klemke R, Wahl G, Gray PC. Abstract 3035: Cripto/GRP78 signaling promotes the stem cell phenotype in normal and neoplastic mammary epithelial cells Cancer Research. 74: 3035-3035. DOI: 10.1158/1538-7445.Am2014-3035 |
0.768 |
|
2014 |
Panopoulos AD, Hishida Y, Wu M, Ruiz S, Batchelder E, Hishida T, Kelber JA, Gray PC, Belmonte JCI. Abstract 1932: Parallel functions of the endoplasmic reticulum chaperone protein GRP78 in tumorigenesis and the induction of pluripotency Cancer Research. 74: 1932-1932. DOI: 10.1158/1538-7445.Am2014-1932 |
0.6 |
|
2013 |
Klemke RL, Jiang X, Choi S, Kelber JA. Proteomic and biochemical methods to study the cytoskeletome. Methods in Molecular Biology (Clifton, N.J.). 1046: 203-18. PMID 23868590 DOI: 10.1007/978-1-62703-538-5_12 |
0.651 |
|
2013 |
Stoletov K, Strnadel J, Zardouzian E, Momiyama M, Park FD, Kelber JA, Pizzo DP, Hoffman R, VandenBerg SR, Klemke RL. Role of connexins in metastatic breast cancer and melanoma brain colonization. Journal of Cell Science. 126: 904-13. PMID 23321642 DOI: 10.1242/Jcs.112748 |
0.753 |
|
2013 |
Spike BT, Engle DD, Lin JC, Kelber JA, La J, Cheung SK, Booker E, Rodewald R, Dravis C, Gray PC, Wahl GM. Abstract A136: Deconstructing stemness from the fetal mammary perspective Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-A136 |
0.516 |
|
2013 |
Metildi CA, Kaushal S, Strnadel J, Wright T, Kelber JA, Klemke RL, Hoffman RM, Bouvet M. Abstract 4911: Aggressive variants isolated from human pancreatic cancer passaging in mice are enriched in stem cell markers and PEAK1 expression. Cancer Research. 73: 4911-4911. DOI: 10.1158/1538-7445.Am2013-4911 |
0.726 |
|
2013 |
Metildi C, Kaushal S, Strnadel J, Wright T, Kelber J, Klemke R, Hoffman R, Bouvet M. Serial In Vivo Passaging of Human Pancreatic Tumors in Nude Mice Results in Aggressive Variants Enriched in Stem Cell Markers and PEAK1 Expression Journal of Surgical Research. 179: 240. DOI: 10.1016/J.Jss.2012.10.447 |
0.69 |
|
2012 |
Soman P, Kelber JA, Lee JW, Wright TN, Vecchio KS, Klemke RL, Chen S. Cancer cell migration within 3D layer-by-layer microfabricated photocrosslinked PEG scaffolds with tunable stiffness. Biomaterials. 33: 7064-70. PMID 22809641 DOI: 10.1016/J.Biomaterials.2012.06.012 |
0.664 |
|
2012 |
Kelber JA, Reno T, Kaushal S, Metildi C, Wright T, Stoletov K, Weems JM, Park FD, Mose E, Wang Y, Hoffman RM, Lowy AM, Bouvet M, Klemke RL. KRas induces a Src/PEAK1/ErbB2 kinase amplification loop that drives metastatic growth and therapy resistance in pancreatic cancer. Cancer Research. 72: 2554-64. PMID 22589274 DOI: 10.1158/0008-5472.Can-11-3552 |
0.738 |
|
2012 |
Kelber JA, Reno T, Kaushal S, Metildi C, Stoletov K, Weems J, Park FD, Wright T, Mose E, Hoffman RM, Lowy AM, Bouvet MM, Klemke RL. Abstract 4167: KRas induces a Src/PEAK1/ErbB2 kinase amplification loop to drive pancreatic cancer growth, metastasis and therapy resistance Cancer Research. 72: 4167-4167. DOI: 10.1158/1538-7445.Am2012-4167 |
0.739 |
|
2012 |
Spike BT, Kelber JA, Kalathur M, Booker E, Lipianskaya J, Klemke R, Vale W, Wahl G, Gray PC. Abstract 3493: Soluble ALK4 extracellular domain antagonizes the cancer/stem cell phenotype caused by Nodal and Cripto signaling in mammary epithelia Cancer Research. 72: 3493-3493. DOI: 10.1158/1538-7445.Am2012-3493 |
0.793 |
|
2012 |
Metildi CA, Kaushal S, Kelber J, Wright T, Snyder CS, Klemke R, Hoffman RM, Bouvet M. Abstract 3375: In vivo passaging of primary pancreatic tumor enriches for stem cells and PEAK expression Cancer Research. 72: 3375-3375. DOI: 10.1158/1538-7445.Am2012-3375 |
0.733 |
|
2011 |
Kelber JA, Klemke RL. The Actin Cytoskeleton Cellular Domains. 197-212. DOI: 10.1002/9781118015759.ch12 |
0.519 |
|
2010 |
Kelber JA, Klemke RL. PEAK1, a novel kinase target in the fight against cancer. Oncotarget. 1: 219-23. PMID 21301050 DOI: 10.18632/Oncotarget.128 |
0.674 |
|
2010 |
Wang Y, Kelber JA, Tran Cao HS, Cantin GT, Lin R, Wang W, Kaushal S, Bristow JM, Edgington TS, Hoffman RM, Bouvet M, Yates JR, Klemke RL. Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected]. Proceedings of the National Academy of Sciences of the United States of America. 107: 10920-5. PMID 20534451 DOI: 10.1073/Pnas.0914776107 |
0.725 |
|
2010 |
Stoletov K, Kato H, Zardouzian E, Kelber J, Yang J, Shattil S, Klemke R. Visualizing extravasation dynamics of metastatic tumor cells. Journal of Cell Science. 123: 2332-41. PMID 20530574 DOI: 10.1242/Jcs.069443 |
0.721 |
|
2010 |
Spike BT, Kelber JA, Booker EC, Klemke RL, Wahl GM, Vale WW, Gray PC. Abstract 4006: Soluble ALK4 extracellular domain antagonizes oncogenic Cripto signaling and inhibits tumor growth Cancer Research. 70: 4006-4006. DOI: 10.1158/1538-7445.Am10-4006 |
0.696 |
|
2010 |
Wang Y, Kelber JA, Tran Cao HS, Cantin GT, Lin R, Wang W, Kaushal S, Bristow JM, Edgington TS, Hoffman RM, Bouvet M, Yates JR, Klemke RL. Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progession (Proceedings of the National Academy of Sciences of the United States of America (2010) 107, 24 (10920-10925) DOI: 10.1073/pnas.0914776107) Proceedings of the National Academy of Sciences of the United States of America. 107: 13556. DOI: 10.1073/Pnas.1008849107 |
0.669 |
|
2009 |
Kelber JA, Panopoulos AD, Shani G, Booker EC, Belmonte JC, Vale WW, Gray PC. Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways. Oncogene. 28: 2324-36. PMID 19421146 DOI: 10.1038/Onc.2009.97 |
0.555 |
|
2008 |
Kelber JA, Shani G, Booker EC, Vale WW, Gray PC. Cripto is a noncompetitive activin antagonist that forms analogous signaling complexes with activin and nodal. The Journal of Biological Chemistry. 283: 4490-500. PMID 18089557 DOI: 10.1074/Jbc.M704960200 |
0.445 |
|
2008 |
Shani G, Fischer WH, Justice NJ, Kelber JA, Vale W, Gray PC. GRP78 and Cripto form a complex at the cell surface and collaborate to inhibit transforming growth factor beta signaling and enhance cell growth. Molecular and Cellular Biology. 28: 666-77. PMID 17991893 DOI: 10.1128/Mcb.01716-07 |
0.558 |
|
2008 |
Gray PC, Shani G, Aung K, Kelber J, Vale W. Cripto binds transforming growth factor β (TGF-β) and inhibits TGF-β signaling (Molecular and Cellular Biology (2006) 26, 24, (9268-9278)) Molecular and Cellular Biology. 28: 7260. DOI: 10.1128/Mcb.01609-08 |
0.462 |
|
2006 |
Gray PC, Shani G, Aung K, Kelber J, Vale W. Cripto binds transforming growth factor beta (TGF-beta) and inhibits TGF-beta signaling. Molecular and Cellular Biology. 26: 9268-78. PMID 17030617 DOI: 10.1128/Mcb.01168-06 |
0.455 |
|
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