| Year |
Citation |
Score |
| 2023 |
Cook AL, Sur S, Dobbyn L, Watson E, Cohen JD, Ptak B, Lee BS, Paul S, Hsiue E, Popoli M, Vogelstein B, Papadopoulos N, Bettegowda C, Gabrielson K, Zhou S, ... Kinzler KW, et al. Identification of nonsense-mediated decay inhibitors that alter the tumor immune landscape. Biorxiv : the Preprint Server For Biology. PMID 38234817 DOI: 10.1101/2023.12.28.573594 |
0.315 |
|
| 2023 |
Wright KM, DiNapoli SR, Miller MS, Aitana Azurmendi P, Zhao X, Yu Z, Chakrabarti M, Shi W, Douglass J, Hwang MS, Hsiue EH, Mog BJ, Pearlman AH, Paul S, Konig MF, ... ... Kinzler KW, et al. Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nature Communications. 14: 5063. PMID 37604828 DOI: 10.1038/s41467-023-40821-w |
0.647 |
|
| 2023 |
Mattox AK, Douville C, Wang Y, Popoli M, Ptak J, Silliman N, Dobbyn L, Schaefer J, Lu S, Pearlman AH, Cohen JD, Tie J, Gibbs P, Lahouel K, Bettegowda C, ... ... Kinzler KW, et al. The origin of highly elevated cell-free DNA in healthy individuals and patients with pancreatic, colorectal, lung, or ovarian cancer. Cancer Discovery. PMID 37565753 DOI: 10.1158/2159-8290.CD-21-1252 |
0.515 |
|
| 2023 |
Douville C, Curtis S, Summers M, Azad TD, Rincon-Torroella J, Wang Y, Mattox A, Avigdor B, Dudley J, Materi J, Raj D, Nair S, Bhanja D, Tuohy K, Dobbyn L, ... ... Kinzler KW, et al. Seq-ing the SINEs of central nervous system tumors in cerebrospinal fluid. Cell Reports. Medicine. 4: 101148. PMID 37552989 DOI: 10.1016/j.xcrm.2023.101148 |
0.489 |
|
| 2023 |
Rincon-Torroella J, Molin MD, Mog B, Han G, Watson E, Wyhs N, Ishiyama S, Ahmedna T, Minn I, Azad NS, Bettegowda C, Papadopoulos N, Kinzler KW, Zhou S, Vogelstein B, et al. ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1. Biorxiv : the Preprint Server For Biology. PMID 37546808 DOI: 10.1101/2023.07.23.550207 |
0.482 |
|
| 2023 |
Wang Y, Douville C, Cohen JD, Mattox A, Curtis S, Silliman N, Popoli M, Ptak J, Dobbyn L, Nehme N, Dudley JC, Summers M, Zhang M, Ho-Pham LT, Tran BNH, ... ... Kinzler KW, et al. Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220704120. PMID 37014860 DOI: 10.1073/pnas.2220704120 |
0.498 |
|
| 2023 |
Lu S, Mattox AK, Aitana Azurmendi P, Christodoulou I, Wright KM, Popoli M, Chen Z, Sur S, Li Y, Bonifant CL, Bettegowda C, Papadopoulos N, Zhou S, Gabelli SB, Vogelstein B, ... Kinzler KW, et al. The rapid and highly parallel identification of antibodies with defined biological activities by SLISY. Nature Communications. 14: 17. PMID 36596784 DOI: 10.1038/s41467-022-35668-6 |
0.646 |
|
| 2022 |
Cook AL, Wyhs N, Sur S, Ptak B, Popoli M, Dobbyn L, Papadopoulos T, Bettegowda C, Papadopoulos N, Vogelstein B, Zhou S, Kinzler KW. An isogenic cell line panel for sequence-based screening of targeted anticancer drugs. Iscience. 25: 104437. PMID 35692635 DOI: 10.1016/j.isci.2022.104437 |
0.485 |
|
| 2022 |
Sengupta S, Board NL, Wu F, Moskovljevic M, Douglass J, Zhang J, Reinhold BR, Duke-Cohan J, Yu J, Reed MC, Tabdili Y, Azurmendi A, Fray EJ, Zhang H, Hsiue EH, ... ... Kinzler KW, et al. TCR-mimic bispecific antibodies to target the HIV-1 reservoir. Proceedings of the National Academy of Sciences of the United States of America. 119: e2123406119. PMID 35394875 DOI: 10.1073/pnas.2123406119 |
0.517 |
|
| 2022 |
Pearlman AH, Hwang MS, Konig MF, Hsiue EH, Douglass J, DiNapoli SR, Mog BJ, Bettegowda C, Pardoll DM, Gabelli SB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Author Correction: Targeting public neoantigens for cancer immunotherapy. Nature Cancer. 2: 865-867. PMID 35122030 DOI: 10.1038/s43018-021-00246-0 |
0.655 |
|
| 2021 |
Pearlman AH, Hwang MS, Konig MF, Hsiue EH, Douglass J, DiNapoli SR, Mog BJ, Bettegowda C, Pardoll DM, Gabelli SB, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Targeting public neoantigens for cancer immunotherapy. Nature Cancer. 2: 487-497. PMID 34676374 DOI: 10.1038/s43018-021-00210-y |
0.699 |
|
| 2021 |
Hwang MS, Miller MS, Thirawatananond P, Douglass J, Wright KM, Hsiue EH, Mog BJ, Aytenfisu TY, Murphy MB, Aitana Azurmendi P, Skora AD, Pearlman AH, Paul S, DiNapoli SR, Konig MF, ... ... Kinzler KW, et al. Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nature Communications. 12: 5271. PMID 34489470 DOI: 10.1038/s41467-021-25605-4 |
0.684 |
|
| 2021 |
Naidoo J, Schreck KC, Fu W, Hu C, Carvajal-Gonzalez A, Connolly RM, Santa-Maria CA, Lipson EJ, Holdhoff M, Forde PM, Douville C, Riemer J, Barnes A, Redmond KJ, Kleinberg L, ... ... Kinzler KW, et al. Pembrolizumab for patients with leptomeningeal metastasis from solid tumors: efficacy, safety, and cerebrospinal fluid biomarkers. Journal For Immunotherapy of Cancer. 9. PMID 34380662 DOI: 10.1136/jitc-2021-002473 |
0.447 |
|
| 2021 |
Rose L, Graham L, Koenecke A, Powell M, Xiong R, Shen Z, Mench B, Kinzler KW, Bettegowda C, Vogelstein B, Athey S, Vogelstein JT, Konig MF, Wagner TH. The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality From COVID-19. Frontiers in Medicine. 8: 637647. PMID 33869251 DOI: 10.3389/fmed.2021.637647 |
0.383 |
|
| 2021 |
Hwang MS, Mog BJ, Douglass J, Pearlman AH, Hsiue EH, Paul S, DiNapoli SR, Konig MF, Pardoll DM, Gabelli SB, Bettegowda C, Papadopoulos N, Vogelstein B, Zhou S, Kinzler KW. Targeting loss of heterozygosity for cancer-specific immunotherapy. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33731480 DOI: 10.1073/pnas.2022410118 |
0.693 |
|
| 2021 |
Paul S, Pearlman AH, Douglass J, Mog BJ, Hsiue EH, Hwang MS, DiNapoli SR, Konig MF, Brown PA, Wright KM, Sur S, Gabelli SB, Li Y, Ghiaur G, Pardoll D, ... ... Kinzler KW, et al. TCR beta chain-directed bispecific antibodies for the treatment of T-cell cancers. Science Translational Medicine. PMID 33649188 DOI: 10.1126/scitranslmed.abd3595 |
0.662 |
|
| 2021 |
Hsiue EH, Wright KM, Douglass J, Hwang MS, Mog BJ, Pearlman AH, Paul S, DiNapoli SR, Konig MF, Wang Q, Schaefer A, Miller MS, Skora AD, Azurmendi PA, Murphy MB, ... ... Kinzler KW, et al. Targeting a neoantigen derived from a common mutation. Science (New York, N.Y.). PMID 33649166 DOI: 10.1126/science.abc8697 |
0.728 |
|
| 2021 |
Douglass J, Hsiue EH, Mog BJ, Hwang MS, DiNapoli SR, Pearlman AH, Miller MS, Wright KM, Azurmendi PA, Wang Q, Paul S, Schaefer A, Skora AD, Molin MD, Konig MF, ... ... Kinzler KW, et al. Bispecific antibodies targeting mutant neoantigens. Science Immunology. 6. PMID 33649101 DOI: 10.1126/sciimmunol.abd5515 |
0.684 |
|
| 2021 |
Douville C, Moinova HR, Thota PN, Shaheen NJ, Iyer PG, Canto MI, Wang JS, Dumot J, Faulx A, Kinzler KW, Papadopoulos N, Vogelstein B, Markowitz SD, Bettegowda C, Willis JE, et al. Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients with Barrett's Esophagus. Gastroenterology. PMID 33493502 DOI: 10.1053/j.gastro.2021.01.209 |
0.451 |
|
| 2020 |
Rose L, Graham L, Koenecke A, Powell M, Xiong R, Shen Z, Kinzler KW, Bettegowda C, Vogelstein B, Konig MF, Athey S, Vogelstein JT, Wagner TH. The Association Between Alpha-1 Adrenergic Receptor Antagonists and In-Hospital Mortality from COVID-19. Medrxiv : the Preprint Server For Health Sciences. PMID 33398294 DOI: 10.1101/2020.12.18.20248346 |
0.381 |
|
| 2020 |
Vogelstein JT, Powell M, Koenecke A, Xiong R, Fischer N, Huq S, Khalafallah AM, Caffo B, Stuart EA, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S, Bettegowda C, Konig MF, et al. Alpha-1 adrenergic receptor antagonists for preventing acute respiratory distress syndrome and death from cytokine storm syndrome. Arxiv. PMID 32550250 |
0.386 |
|
| 2020 |
Konig MF, Powell MA, Staedtke V, Bai RY, Thomas DL, Fischer NM, Huq S, Khalafallah AM, Koenecke A, Xiong R, Mensh B, Papadopoulos N, Kinzler KW, Vogelstein B, Vogelstein JT, et al. Preventing cytokine storm syndrome in COVID-19 using α-1 adrenergic receptor antagonists. The Journal of Clinical Investigation. PMID 32352407 DOI: 10.1172/Jci139642 |
0.451 |
|
| 2020 |
Lennon AM, Buchanan AH, Kinde I, Warren A, Honushefsky A, Cohain AT, Ledbetter DH, Sanfilippo F, Sheridan K, Rosica D, Adonizio CS, Hwang HJ, Lahouel K, Cohen JD, Douville C, ... ... Kinzler KW, et al. Feasibility of blood testing combined with PET-CT to screen for cancer and guide intervention. Science (New York, N.Y.). PMID 32345712 DOI: 10.1126/Science.Abb9601 |
0.449 |
|
| 2020 |
Douville C, Cohen JD, Ptak J, Popoli M, Schaefer J, Silliman N, Dobbyn L, Schoen RE, Tie J, Gibbs P, Goggins M, Wolfgang CL, Wang TL, Shih IM, Karchin R, ... ... Kinzler KW, et al. Assessing aneuploidy with repetitive element sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 32075918 DOI: 10.1073/Pnas.1910041117 |
0.483 |
|
| 2019 |
Lahouel K, Younes L, Danilova L, Giardiello FM, Hruban RH, Groopman J, Kinzler KW, Vogelstein B, Geman D, Tomasetti C. Revisiting the tumorigenesis timeline with a data-driven generative model. Proceedings of the National Academy of Sciences of the United States of America. PMID 31882448 DOI: 10.1073/Pnas.1914589117 |
0.443 |
|
| 2019 |
Miller MS, Douglass J, Hwang MS, Skora AD, Murphy M, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S, Gabelli SB. An engineered antibody fragment targeting mutant β-catenin via Major Histocompatibility Complex I neoantigen presentation. The Journal of Biological Chemistry. PMID 31690625 DOI: 10.1074/Jbc.Ra119.010251 |
0.596 |
|
| 2019 |
Wang Q, Douglass J, Hwang MS, Hsiue EH, Mog BJ, Zhang M, Papadopoulos N, Kinzler KW, Zhou S, Vogelstein B. Direct Detection and Quantification of Neo-antigens. Cancer Immunology Research. PMID 31527070 DOI: 10.1158/2326-6066.Cir-19-0107 |
0.325 |
|
| 2019 |
Rodriguez Pena MDC, Springer SU, Taheri D, Li L, Tregnago AC, Eich ML, Eltoum IA, VandenBussche CJ, Papadopoulos N, Kinzler KW, Vogelstein B, Netto GJ. Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal urine cytology. Virchows Archiv : An International Journal of Pathology. PMID 31482302 DOI: 10.1007/S00428-019-02654-1 |
0.325 |
|
| 2019 |
Mattox AK, Bettegowda C, Zhou S, Papadopoulos N, Kinzler KW, Vogelstein B. Applications of liquid biopsies for cancer. Science Translational Medicine. 11. PMID 31462507 DOI: 10.1126/Scitranslmed.Aay1984 |
0.522 |
|
| 2019 |
Reiter JG, Baretti M, Gerold JM, Makohon-Moore AP, Daud A, Iacobuzio-Donahue CA, Azad NS, Kinzler KW, Nowak MA, Vogelstein B. An analysis of genetic heterogeneity in untreated cancers. Nature Reviews. Cancer. PMID 31455892 DOI: 10.1038/S41568-019-0185-X |
0.307 |
|
| 2019 |
Lee B, Lipton L, Cohen J, Tie J, Javed AA, Li L, Goldstein D, Burge M, Cooray P, Nagrial A, Tebbutt NC, Thomson B, Nikfarjam M, Harris M, Haydon A, ... ... Kinzler KW, et al. Circulating tumor DNA as a potential marker of adjuvant chemotherapy benefit following surgery for localised pancreatic cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 31250894 DOI: 10.1093/Annonc/Mdz200 |
0.336 |
|
| 2019 |
Eich ML, Rodriguez Pena MDC, Springer SU, Taheri D, Tregnago AC, Salles DC, Bezerra SM, Cunha IW, Fujita K, Ertoy D, Bivalacqua TJ, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, et al. Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31028363 DOI: 10.1038/S41379-019-0276-Y |
0.414 |
|
| 2019 |
Smith KN, Llosa NJ, Cottrell TR, Siegel N, Fan H, Suri P, Chan HY, Guo H, Oke T, Awan AH, Verde F, Danilova L, Anagnostou V, Tam AJ, Luber BS, ... ... Kinzler KW, et al. Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1. Journal For Immunotherapy of Cancer. 7: 40. PMID 30744692 DOI: 10.1186/S40425-018-0492-X |
0.341 |
|
| 2019 |
Wong R, Tie J, Lee M, Cohen J, Wang Y, Li L, Ma S, Christie M, Kosmider S, Tomasetti C, Papadopoulos N, Kinzler K, Vogelstein B, Gibbs P. The potential role of circulating tumor DNA (ctDNA) in the further investigation of colorectal cancer patients with non-specific findings on standard investigations. International Journal of Cancer. PMID 30628066 DOI: 10.1002/Ijc.32117 |
0.335 |
|
| 2018 |
Gallia GL, Zhang M, Ning Y, Haffner MC, Batista D, Binder ZA, Bishop JA, Hann CL, Hruban RH, Ishii M, Klein AP, Reh DD, Rooper LM, Salmasi V, Tamargo RJ, ... ... Kinzler KW, et al. Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma. Nature Communications. 9: 5410. PMID 30575736 DOI: 10.1038/S41467-018-07578-Z |
0.575 |
|
| 2018 |
Wu RC, Wang P, Lin SF, Zhang M, Song Q, Chu T, Wang BG, Kurman RJ, Vang R, Kinzler K, Tomasetti C, Jiao Y, Shih IM, Wang TL. Genomic landscape and evolutionary trajectories of ovarian cancer early precursor lesions. The Journal of Pathology. PMID 30560554 DOI: 10.1002/Path.5219 |
0.303 |
|
| 2018 |
Palsgrove DN, Taheri D, Springer SU, Cowan M, Guner G, Mendoza Rodriguez MA, Del Carmen Rodriguez Pena M, Wang Y, Kinde I, Ricardo BFP, Cunha I, Fujita K, Ertoy D, Kinzler KW, Bivalacqua TJ, et al. Targeted sequencing of Plasmacytoid urothelial carcinoma reveals frequent TERT promoter mutations. Human Pathology. PMID 30447301 DOI: 10.1016/J.Humpath.2018.10.033 |
0.43 |
|
| 2018 |
Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, ... ... Kinzler KW, et al. Correction: Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy. Elife. 7. PMID 30418154 DOI: 10.7554/Elife.43237 |
0.414 |
|
| 2018 |
Reiter JG, Makohon-Moore AP, Gerold JM, Heyde A, Attiyeh MA, Kohutek ZA, Tokheim CJ, Brown A, DeBlasio RM, Niyazov J, Zucker A, Karchin R, Kinzler KW, Iacobuzio-Donahue CA, Vogelstein B, et al. Minimal functional driver gene heterogeneity among untreated metastases. Science (New York, N.Y.). 361: 1033-1037. PMID 30190408 DOI: 10.1126/Science.Aat7171 |
0.352 |
|
| 2018 |
Wang Y, Li L, Douville C, Cohen JD, Yen TT, Kinde I, Sundfelt K, Kjær SK, Hruban RH, Shih IM, Wang TL, Kurman RJ, Springer S, Ptak J, Popoli M, ... ... Kinzler KW, et al. Evaluation of liquid from the Papanicolaou test and other liquid biopsies for the detection of endometrial and ovarian cancers. Science Translational Medicine. 10. PMID 29563323 DOI: 10.1126/Scitranslmed.Aap8793 |
0.37 |
|
| 2018 |
Springer SU, Chen CH, Rodriguez Pena MDC, Li L, Douville C, Wang Y, Cohen JD, Taheri D, Silliman N, Schaefer J, Ptak J, Dobbyn L, Papoli M, Kinde I, Afsari B, ... ... Kinzler KW, et al. Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy. Elife. 7. PMID 29557778 DOI: 10.7554/Elife.32143 |
0.419 |
|
| 2018 |
Douville C, Springer S, Kinde I, Cohen JD, Hruban RH, Lennon AM, Papadopoulos N, Kinzler KW, Vogelstein B, Karchin R. Detection of aneuploidy in patients with cancer through amplification of long interspersed nucleotide elements (LINEs). Proceedings of the National Academy of Sciences of the United States of America. PMID 29432176 DOI: 10.1073/Pnas.1717846115 |
0.371 |
|
| 2018 |
Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, ... ... Kinzler KW, et al. Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science (New York, N.Y.). PMID 29348365 DOI: 10.1126/Science.Aar3247 |
0.561 |
|
| 2018 |
Eich M, Springer S, Rodriguez Pena M, Taheri D, Tregnago A, Bezerra S, Cunha I, Fujita K, Ertoy D, Bivalacqua T, Papadopoulos N, Kinzler K, Vogelstein B, Netto G. UroSEEK signature in invasive bladder cancer European Urology Supplements. 17: e2493-e2495. DOI: 10.1016/S1569-9056(18)32978-6 |
0.332 |
|
| 2018 |
Springer S, Rodriguez Pena MDC, Tregnago A, Taheri D, Bezerra S, Cunha I, Fujita K, Baydar D, Bivalacqua T, Papadopoulos N, Kinzler KW, Vogelstein B, Netto G. MP65-14 UROSEEK: A NOVEL NON-INVASIVE MOLECULAR ASSAY FOR SURVEILLANCE OF BLADDER CANCER Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.2080 |
0.333 |
|
| 2018 |
Springer S, Rodriguez Pena MDC, Tregnago A, Taheri D, Bezerra S, Cunha I, Fujita K, Baydar D, Bivalacqua T, Papadopoulos N, Kinzler KW, Vogelstein B, Netto G. MP65-13 UROSEEK: A NOVEL NON-INVASIVE MOLECULAR METHOD FOR EARLY DETECTION OF BLADDER CANCER Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.2079 |
0.32 |
|
| 2017 |
Cohen JD, Javed AA, Thoburn C, Wong F, Tie J, Gibbs P, Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M, Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, ... ... Kinzler KW, et al. Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874546 DOI: 10.1073/Pnas.1704961114 |
0.426 |
|
| 2017 |
Rodriguez Pena MDC, Tregnago AC, Eich ML, Springer S, Wang Y, Taheri D, Ertoy D, Fujita K, Bezerra SM, Cunha IW, Raspollini MR, Yu L, Bivalacqua TJ, Papadopoulos N, Kinzler KW, et al. Spectrum of genetic mutations in de novo PUNLMP of the urinary bladder. Virchows Archiv : An International Journal of Pathology. PMID 28597078 DOI: 10.1007/S00428-017-2164-5 |
0.44 |
|
| 2017 |
Le DT, Durham JN, Smith KN, Wang H, Bartlett BR, Aulakh LK, Lu S, Kemberling H, Wilt C, Luber BS, Wong F, Azad NS, Rucki AA, Laheru D, Donehower R, ... ... Kinzler KW, et al. Mismatch-repair deficiency predicts response of solid tumors to PD-1 blockade. Science (New York, N.Y.). PMID 28596308 DOI: 10.1126/Science.Aan6733 |
0.4 |
|
| 2017 |
Anglesio MS, Papadopoulos N, Ayhan A, Nazeran TM, Noë M, Horlings HM, Lum A, Jones S, Senz J, Seckin T, Ho J, Wu RC, Lac V, Ogawa H, Tessier-Cloutier B, ... ... Kinzler KW, et al. Cancer-Associated Mutations in Endometriosis without Cancer. The New England Journal of Medicine. 376: 1835-1848. PMID 28489996 DOI: 10.1056/Nejmoa1614814 |
0.38 |
|
| 2017 |
Mattox AK, Wang Y, Springer S, Cohen JD, Yegnasubramanian S, Nelson WG, Kinzler KW, Vogelstein B, Papadopoulos N. Bisulfite-converted duplexes for the strand-specific detection and quantification of rare mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28416672 DOI: 10.1073/Pnas.1701382114 |
0.335 |
|
| 2017 |
Holdhoff M, Cairncross GJ, Kollmeyer TM, Zhang M, Zhang P, Mehta MP, Werner-Wasik M, Souhami L, Bahary JP, Kwok Y, Hartford AC, Chakravarti A, Yegnasubramanian S, Vogelstein B, Papadopoulos N, ... Kinzler K, et al. Genetic landscape of extreme responders with anaplastic oligodendroglioma. Oncotarget. PMID 28388591 DOI: 10.18632/Oncotarget.16773 |
0.485 |
|
| 2017 |
Miller MS, Maheshwari S, McRobb FM, Kinzler KW, Amzel LM, Vogelstein B, Gabelli SB. Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design. Bioorganic & Medicinal Chemistry. PMID 28129991 DOI: 10.1016/J.Bmc.2017.01.012 |
0.576 |
|
| 2017 |
Makohon-Moore AP, Zhang M, Reiter JG, Bozic I, Allen B, Kundu D, Chatterjee K, Wong F, Jiao Y, Kohutek ZA, Hong J, Attiyeh M, Javier B, Wood LD, Hruban RH, ... ... Kinzler KW, et al. Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer. Nature Genetics. PMID 28092682 DOI: 10.1038/Ng.3764 |
0.324 |
|
| 2017 |
Lee B, Cohen J, Lipton LR, Tie J, Javed AA, Li L, Goldstein D, Cooray P, Nagrial A, Burge ME, Tebbutt NC, Nikfarjam M, Harris M, O'Broin-Lennon AM, Wolfgang CL, ... ... Kinzler KW, et al. Potential role of circulating tumor DNA (ctDNA) in the early diagnosis and post-operative management of localised pancreatic cancer. Journal of Clinical Oncology. 35: 4101-4101. DOI: 10.1200/Jco.2017.35.15_Suppl.4101 |
0.362 |
|
| 2017 |
Tie J, Cohen J, Wang Y, Li L, Kinde I, Elsaleh H, Wong R, Kosmider S, Yip D, Lee M, Tran B, Burge ME, Goldstein D, Singh MS, Diaz LA, ... ... Kinzler KW, et al. The potential of circulating tumor DNA (ctDNA) to guide adjuvant chemotherapy decision making in locally advanced rectal cancer (LARC). Journal of Clinical Oncology. 35: 3521-3521. DOI: 10.1200/Jco.2017.35.15_Suppl.3521 |
0.314 |
|
| 2017 |
Papadopoulos N, Wang Y, Cohen J, Hruban R, Gibbs P, Tie J, Diaz L, Kinzler K, Vogelstein B. Abstract IA17: Non-invasive detection of somatic mutations in the management of CRC Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-Ia17 |
0.421 |
|
| 2017 |
Kinzler KW. Abstract IA03: Lessons from colorectal cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-Ia03 |
0.376 |
|
| 2016 |
Rettig EM, Talbot CC, Sausen M, Jones S, Bishop JA, Wood LD, Tokheim C, Niknafs N, Karchin R, Fertig E, Wheelan S, Marchionni L, Considine M, Ling S, Fakhry C, ... ... Kinzler KW, et al. Correction: Whole-genome sequencing of salivary gland adenoid cystic carcinoma (Cancer Prevention Research (2016) 9 (265-274) DOI: 10.1158/1940-6207.CAPR-15-0316) Cancer Prevention Research. 11. PMID 28642227 DOI: 10.1158/1940-6207.Capr-17-0178 |
0.305 |
|
| 2016 |
Tokheim CJ, Papadopoulos N, Kinzler KW, Vogelstein B, Karchin R. Evaluating the evaluation of cancer driver genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 27911828 DOI: 10.1073/Pnas.1616440113 |
0.373 |
|
| 2016 |
Kinzler K, Vogelstein B. Necessity Is The Mother of Invention: The Development of Digital Genomics. Clinical Chemistry. PMID 27754860 DOI: 10.1373/Clinchem.2016.262741 |
0.359 |
|
| 2016 |
Morin PJ, Kinzler KW, Sparks AB. β-Catenin Mutations: Insights into the APC Pathway and the Power of Genetics. Cancer Research. 76: 5587-5589. PMID 27698186 DOI: 10.1158/0008-5472.Can-16-2387 |
0.333 |
|
| 2016 |
Hoang ML, Kinde I, Tomasetti C, McMahon KW, Rosenquist TA, Grollman AP, Kinzler KW, Vogelstein B, Papadopoulos N. Genome-wide quantification of rare somatic mutations in normal human tissues using massively parallel sequencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 27528664 DOI: 10.1073/Pnas.1607794113 |
0.343 |
|
| 2016 |
Nguyen D, Taheri D, Springer S, Cowan M, Guner G, Rodriguez MA, Wang Y, Kinde I, VandenBussche CJ, Olson MT, Ricardo BF, Cunha I, Fujita K, Ertoy D, Kinzler KW, et al. High prevalence of TERT promoter mutations in micropapillary urothelial carcinoma. Virchows Archiv : An International Journal of Pathology. PMID 27520411 DOI: 10.1007/S00428-016-2001-2 |
0.38 |
|
| 2016 |
Wang Y, Sundfeldt K, Mateoiu C, Shih IM, Kurman RJ, Schaefer J, Silliman N, Kinde I, Springer S, Foote M, Kristjansdottir B, James N, Kinzler KW, Papadopoulos N, Diaz LA, et al. Diagnostic potential of tumor DNA from ovarian cyst fluid. Elife. 5. PMID 27421040 DOI: 10.7554/Elife.15175 |
0.416 |
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| 2016 |
Tie J, Wang Y, Tomasetti C, Li L, Springer S, Kinde I, Silliman N, Tacey M, Wong HL, Christie M, Kosmider S, Skinner I, Wong R, Steel M, Tran B, ... ... Kinzler KW, et al. Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer. Science Translational Medicine. 8: 346ra92. PMID 27384348 DOI: 10.1126/Scitranslmed.Aaf6219 |
0.336 |
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| 2016 |
Hao Y, Samuels Y, Li Q, Krokowski D, Guan BJ, Wang C, Jin Z, Dong B, Cao B, Feng X, Xiang M, Xu C, Fink S, Meropol NJ, Xu Y, ... ... Kinzler KW, et al. Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer. Nature Communications. 7: 11971. PMID 27321283 DOI: 10.1038/Ncomms11971 |
0.404 |
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| 2016 |
Leung F, Kulasingam V, Diamandis EP, Hoon DS, Kinzler K, Pantel K, Alix-Panabières C. Circulating Tumor DNA as a Cancer Biomarker: Fact or Fiction? Clinical Chemistry. PMID 27259816 DOI: 10.1373/Clinchem.2016.260331 |
0.388 |
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| 2016 |
Cowan M, Springer S, Nguyen D, Taheri D, Guner G, Mendoza Rodriguez MA, Wang Y, Kinde I, Del Carmen Rodriguez Pena M, VandenBussche CJ, Olson M, Cunha I, Fujita K, Ertoy D, Kinzler K, et al. Detection of TERT promoter mutations in primary adenocarcinoma of the urinary bladder. Human Pathology. PMID 26980028 DOI: 10.1016/J.Humpath.2016.02.009 |
0.394 |
|
| 2016 |
Cowan M, Springer S, Nguyen D, Taheri D, Guner G, Rodriguez MA, Wang Y, Kinde I, Bussche CJ, Olson MT, Cunha I, Fujita K, Ertoy D, Bivalacqua TJ, Kinzler K, et al. High prevalence of TERT promoter mutations in primary squamous cell carcinoma of the urinary bladder. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 26965579 DOI: 10.1038/Modpathol.2016.53 |
0.323 |
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| 2016 |
Rettig EM, Talbot C, Sausen M, Jones S, Bishop JA, Wood LD, Tokheim C, Niknafs N, Karchin R, Fertig E, Wheelan S, Marchionni L, Considine M, Fakhry C, Papadopoulos N, ... Kinzler KW, et al. Whole-Genome Sequencing of Salivary Gland Adenoid Cystic Carcinoma. Cancer Prevention Research (Philadelphia, Pa.). PMID 26862087 DOI: 10.1158/1940-6207.Capr-15-0316 |
0.31 |
|
| 2016 |
Robles AI, Traverso G, Zhang M, Roberts NJ, Khan MA, Joseph C, Lauwers GY, Selaru FM, Popoli M, Pittman ME, Ke X, Hruban RH, Meltzer SJ, Kinzler KW, Vogelstein B, et al. Whole-exome Sequencing analyses of Inflammatory Bowel Disease-associated Colorectal Cancers. Gastroenterology. PMID 26764183 DOI: 10.1053/J.Gastro.2015.12.036 |
0.408 |
|
| 2016 |
Wang Y, Sundfeldt K, Mateoiu C, Shih I, Kurman RJ, Schaefer J, Silliman N, Kinde I, Springer S, Foote M, Kristjansdottir B, James N, Kinzler KW, Papadopoulos N, Diaz LA, et al. Author response: Diagnostic potential of tumor DNA from ovarian cyst fluid Elife. DOI: 10.7554/Elife.15175.013 |
0.311 |
|
| 2016 |
Tie J, Wang Y, Springer S, Kinde I, Wong H, Kosmider S, Tran B, Christie M, Thomson BN, Wong R, Burge ME, Shannon J, Kotasek D, Field KM, Strausberg R, ... ... Kinzler KW, et al. Serial circulating tumor DNA (ctDNA) and recurrence risk in patients (pts) with resectable colorectal liver metastasis (CLM). Journal of Clinical Oncology. 34: e15131-e15131. DOI: 10.1200/Jco.2016.34.15_Suppl.E15131 |
0.343 |
|
| 2016 |
Tie J, Wang Y, Tomasetti C, Li L, Springer S, Kinde I, Wong R, Kosmider S, Tran B, Desai J, Hayes TM, Haydon AM, Yip D, Christie M, Strausberg R, ... ... Kinzler KW, et al. The potential of circulating tumor DNA (ctDNA) to reshape the design of clinical trials testing adjuvant therapy in patients with early stage cancers. Journal of Clinical Oncology. 34: 3511-3511. DOI: 10.1200/Jco.2016.34.15_Suppl.3511 |
0.367 |
|
| 2016 |
Holdhoff M, Cairncross JG, Jenkins RB, Bettegowda C, Zhang M, Kollmeyer TM, Yegnasubramanian ST, Grossman SA, Vogelstein B, Papadopoulos N, Kinzler KW, Werner-Wasik M, Souhami L, Bahary J, Kwok Y, et al. Genetic landscape of extreme responders with anaplastic oligodendroglioma: NRG Oncology/RTOG 9402. Journal of Clinical Oncology. 34: 2054-2054. DOI: 10.1200/Jco.2016.34.15_Suppl.2054 |
0.514 |
|
| 2016 |
Hoang ML, Kinde I, Tomasetti C, Rosenquist T, Grollman AP, Kinzler KW, Vogelstein B, Papadopoulos N. Abstract NG01: Accumulation of somatic mutations in normal and cancerous tissues with age Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ng01 |
0.38 |
|
| 2015 |
Roberts NJ, Norris AL, Petersen GM, Bondy ML, Brand R, Gallinger S, Kurtz RC, Olson SH, Rustgi AK, Schwartz AG, Stoffel EM, Syngal S, Zogopoulos G, Ali SZ, Axilbund J, ... ... Kinzler KW, et al. Whole genome sequencing defines the genetic heterogeneity of familial pancreatic cancer. Cancer Discovery. PMID 26658419 DOI: 10.1158/2159-8290.Cd-15-0402 |
0.394 |
|
| 2015 |
Vogelstein B, Kinzler KW. The Path to Cancer --Three Strikes and You're Out. The New England Journal of Medicine. 373: 1895-8. PMID 26559569 DOI: 10.1056/Nejmp1508811 |
0.452 |
|
| 2015 |
Maritschnegg E, Wang Y, Pecha N, Horvat R, Van Nieuwenhuysen E, Vergote I, Heitz F, Sehouli J, Kinde I, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Speiser P, Zeillinger R. Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26552420 DOI: 10.1200/Jco.2015.61.3083 |
0.439 |
|
| 2015 |
Ewing AD, Gacita A, Wood LD, Ma F, Xing D, Kim MS, Manda SS, Abril G, Pereira G, Makohon-Moore A, Looijenga LH, Gillis AJ, Hruban RH, Anders RA, Romans KE, ... ... Kinzler KW, et al. Widespread somatic L1 retrotransposition occurs early during gastrointestinal cancer evolution. Genome Research. PMID 26260970 DOI: 10.1101/Gr.196238.115 |
0.382 |
|
| 2015 |
Skora AD, Douglass J, Hwang MS, Tam AJ, Blosser RL, Gabelli SB, Cao J, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26216968 DOI: 10.1073/Pnas.1511996112 |
0.555 |
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| 2015 |
Wang Y, Springer S, Zhang M, McMahon KW, Kinde I, Dobbyn L, Ptak J, Brem H, Chaichana K, Gallia GL, Gokaslan ZL, Groves ML, Jallo GI, Lim M, Olivi A, ... ... Kinzler KW, et al. Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord. Proceedings of the National Academy of Sciences of the United States of America. PMID 26195750 DOI: 10.1073/Pnas.1511694112 |
0.504 |
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| 2015 |
Perica K, Bieler JG, Schütz C, Varela JC, Douglass J, Skora A, Chiu YL, Oelke M, Kinzler K, Zhou S, Vogelstein B, Schneck JP. Enrichment and Expansion with Nanoscale Artificial Antigen Presenting Cells for Adoptive Immunotherapy. Acs Nano. 9: 6861-71. PMID 26171764 DOI: 10.1021/Acsnano.5B02829 |
0.35 |
|
| 2015 |
Wang Y, Springer S, Mulvey CL, Silliman N, Schaefer J, Sausen M, James N, Rettig EM, Guo T, Pickering CR, Bishop JA, Chung CH, Califano JA, Eisele DW, Fakhry C, ... ... Kinzler KW, et al. Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas. Science Translational Medicine. 7: 293ra104. PMID 26109104 DOI: 10.1126/Scitranslmed.Aaa8507 |
0.514 |
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| 2015 |
Le DT, Uram JN, Wang H, Bartlett BR, Kemberling H, Eyring AD, Skora AD, Luber BS, Azad NS, Laheru D, Biedrzycki B, Donehower RC, Zaheer A, Fisher GA, Crocenzi TS, ... ... Kinzler KW, et al. PD-1 Blockade in Tumors with Mismatch-Repair Deficiency. The New England Journal of Medicine. 372: 2509-20. PMID 26028255 DOI: 10.1200/Jco.2015.33.18_Suppl.Lba100 |
0.359 |
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| 2015 |
Tie J, Kinde I, Wang Y, Wong HL, Roebert J, Christie M, Tacey M, Wong R, Singh M, Karapetis CS, Desai J, Tran B, Strausberg RL, Diaz LA, Papadopoulos N, ... Kinzler KW, et al. Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. PMID 25851626 DOI: 10.1093/Annonc/Mdv177 |
0.385 |
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| 2015 |
Llosa NJ, Cruise M, Tam A, Wicks EC, Hechenbleikner EM, Taube JM, Blosser RL, Fan H, Wang H, Luber BS, Zhang M, Papadopoulos N, Kinzler KW, Vogelstein B, Sears CL, et al. The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints. Cancer Discovery. 5: 43-51. PMID 25358689 DOI: 10.1158/2159-8290.Cd-14-0863 |
0.382 |
|
| 2015 |
Tie J, Wang Y, Kinde I, Steel M, Elsaleh H, Singh MS, Turner NH, Tran B, Strausberg R, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Gibbs P. Circulating tumor DNA (ctDNA) in nonmetastatic colorectal cancer (CRC): Potential role as a screening tool. Journal of Clinical Oncology. 33: 518-518. DOI: 10.1200/Jco.2015.33.3_Suppl.518 |
0.4 |
|
| 2015 |
Miller M, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Abstract PR02: Targeting PI3K: The PIP2 binding site Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-Pr02 |
0.578 |
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| 2015 |
Sur S, Chapiro J, Savic LJ, Kaniappan GS, Reyes J, Duran R, Thiruganasambandam SC, Moats CR, Luo W, Ewald AJ, Zhou S, Kinzler KW, Geschwind J, Vogelstein B. Abstract NG06: The Trojan Horse Strategy: Packaging chemotherapeutics can help alleviate toxicity Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Ng06 |
0.332 |
|
| 2015 |
Llosa NJ, Cruise M, Tam A, Wick E, Hechenbleikner E, Taube J, Blosser L, Fan H, Wang H, Zhang M, Luber B, Papadopoulos N, Kinzler K, Vogelstein B, Sears C, et al. Abstract 451: The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints Cancer Research. 75: 451-451. DOI: 10.1158/1538-7445.Am2015-451 |
0.313 |
|
| 2015 |
Makohon-Moore AP, Zhang M, Reiter JG, Bozic I, Wong F, Jiao Y, Chatterjee K, Nowak MA, Papadopoulos N, Vogelstein B, Kinzler KW, Iacobuzio-Donahue CA. Abstract 4137: Clonal evolution defines the natural history of metastatic pancreatic cancer Cancer Research. 75: 4137-4137. DOI: 10.1158/1538-7445.Am2015-4137 |
0.409 |
|
| 2014 |
Dejea CM, Wick EC, Hechenbleikner EM, White JR, Mark Welch JL, Rossetti BJ, Peterson SN, Snesrud EC, Borisy GG, Lazarev M, Stein E, Vadivelu J, Roslani AC, Malik AA, Wanyiri JW, ... ... Kinzler KW, et al. Microbiota organization is a distinct feature of proximal colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 111: 18321-6. PMID 25489084 DOI: 10.1073/Pnas.1406199111 |
0.374 |
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| 2014 |
Erickson BK, Kinde I, Dobbin ZC, Wang Y, Martin JY, Alvarez RD, Conner MG, Huh WK, Roden RB, Kinzler KW, Papadopoulos N, Vogelstein B, Diaz LA, Landen CN. Detection of somatic TP53 mutations in tampons of patients with high-grade serous ovarian cancer. Obstetrics and Gynecology. 124: 881-5. PMID 25437714 DOI: 10.1097/AOG.0000000000000484 |
0.305 |
|
| 2014 |
Zhang M, Wang Y, Jones S, Sausen M, McMahon K, Sharma R, Wang Q, Belzberg AJ, Chaichana K, Gallia GL, Gokaslan ZL, Riggins GJ, Wolinksy JP, Wood LD, Montgomery EA, ... ... Kinzler KW, et al. Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors. Nature Genetics. 46: 1170-2. PMID 25305755 DOI: 10.1038/Ng.3116 |
0.501 |
|
| 2014 |
Roberts NJ, Zhang L, Janku F, Collins A, Bai RY, Staedtke V, Rusk AW, Tung D, Miller M, Roix J, Khanna KV, Murthy R, Benjamin RS, Helgason T, Szvalb AD, ... ... Kinzler KW, et al. Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses. Science Translational Medicine. 6: 249ra111. PMID 25122639 DOI: 10.1126/Scitranslmed.3008982 |
0.747 |
|
| 2014 |
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Structural basis of nSH2 regulation and lipid binding in PI3Kα. Oncotarget. 5: 5198-208. PMID 25105564 DOI: 10.18632/Oncotarget.2263 |
0.526 |
|
| 2014 |
Kim K, Skora AD, Li Z, Liu Q, Tam AJ, Blosser RL, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Zhou S. Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 11774-9. PMID 25071169 DOI: 10.1073/Pnas.1410626111 |
0.362 |
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| 2014 |
Li R, Faden DL, Fakhry C, Langelier C, Jiao Y, Wang Y, Wilkerson MD, Pedamallu CS, Old M, Lang J, Loyo M, Ahn SM, Tan M, Gooi Z, Chan J, ... ... Kinzler KW, et al. Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke. Head & Neck. PMID 24954188 DOI: 10.1002/Hed.23807 |
0.476 |
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| 2014 |
Lennon AM, Wolfgang CL, Canto MI, Klein AP, Herman JM, Goggins M, Fishman EK, Kamel I, Weiss MJ, Diaz LA, Papadopoulos N, Kinzler KW, Vogelstein B, Hruban RH. The early detection of pancreatic cancer: what will it take to diagnose and treat curable pancreatic neoplasia? Cancer Research. 74: 3381-9. PMID 24924775 DOI: 10.1158/0008-5472.Can-14-0734 |
0.324 |
|
| 2014 |
Esserman LJ, Thompson IM, Reid B, Nelson P, Ransohoff DF, Welch HG, Hwang S, Berry DA, Kinzler KW, Black WC, Bissell M, Parnes H, Srivastava S. Addressing overdiagnosis and overtreatment in cancer: a prescription for change. The Lancet. Oncology. 15: e234-42. PMID 24807866 DOI: 10.1016/S1470-2045(13)70598-9 |
0.32 |
|
| 2014 |
Bettegowda C, Sausen M, Leary RJ, Kinde I, Wang Y, Agrawal N, Bartlett BR, Wang H, Luber B, Alani RM, Antonarakis ES, Azad NS, Bardelli A, Brem H, Cameron JL, ... ... Kinzler KW, et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Science Translational Medicine. 6: 224ra24. PMID 24553385 DOI: 10.1126/Scitranslmed.3007094 |
0.621 |
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| 2014 |
Chan KW, Yu T, Qiao Y, Liu Q, Yang M, Patel H, Liu G, Kinzler KW, Vogelstein B, Bulte JW, van Zijl PC, Hanes J, Zhou S, McMahon MT. A diaCEST MRI approach for monitoring liposomal accumulation in tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. 180: 51-9. PMID 24548481 DOI: 10.1016/J.Jconrel.2014.02.005 |
0.347 |
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| 2014 |
Matthaei H, Wu J, Dal Molin M, Shi C, Perner S, Kristiansen G, Lingohr P, Kalff JC, Wolfgang CL, Kinzler KW, Vogelstein B, Maitra A, Hruban RH. GNAS sequencing identifies IPMN-specific mutations in a subgroup of diminutive pancreatic cysts referred to as "Incipient IPMNs" American Journal of Surgical Pathology. 38: 360-363. PMID 24525507 DOI: 10.1097/Pas.0000000000000117 |
0.339 |
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| 2014 |
Jiao Y, Yonescu R, Offerhaus GJ, Klimstra DS, Maitra A, Eshleman JR, Herman JG, Poh W, Pelosof L, Wolfgang CL, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N, Wood LD. Whole-exome sequencing of pancreatic neoplasms with acinar differentiation. The Journal of Pathology. 232: 428-35. PMID 24293293 DOI: 10.1002/Path.4310 |
0.383 |
|
| 2014 |
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Abstract LB-326: Structural basis of lipid-binding and regulation in PI3Kα Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-326 |
0.596 |
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| 2014 |
Miller MS, Schmidt-Kittler O, Bolduc DM, Brower ET, Chaves-Moreira D, Allaire M, Kinzler KW, Jennings IG, Thompson PE, Cole PA, Amzel LM, Vogelstein B, Gabelli SB. Structural basis of nSH2 regulation and lipid binding in PI3Kα Oncotarget. 5: 5198-5208. |
0.495 |
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| 2013 |
Jiao Y, Pawlik TM, Anders RA, Selaru FM, Streppel MM, Lucas DJ, Niknafs N, Guthrie VB, Maitra A, Argani P, Offerhaus GJ, Roa JC, Roberts LR, Gores GJ, Popescu I, ... ... Kinzler KW, et al. Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas. Nature Genetics. 45: 1470-3. PMID 24185509 DOI: 10.1038/Ng.2813 |
0.381 |
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| 2013 |
Liu G, Bettegowda C, Qiao Y, Staedtke V, Chan KW, Bai R, Li Y, Riggins GJ, Kinzler KW, Bulte JW, McMahon MT, Gilad AA, Vogelstein B, Zhou S, van Zijl PC. Noninvasive imaging of infection after treatment with tumor-homing bacteria using Chemical Exchange Saturation Transfer (CEST) MRI. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 70: 1690-8. PMID 24123389 DOI: 10.1002/Mrm.24955 |
0.527 |
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| 2013 |
Yang J, Hendricks W, Liu G, McCaffery JM, Kinzler KW, Huso DL, Vogelstein B, Zhou S. A nanoparticle formulation that selectively transfects metastatic tumors in mice Proceedings of the National Academy of Sciences of the United States of America. 110: 14717-14722. PMID 23959886 DOI: 10.1073/Pnas.1313330110 |
0.366 |
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| 2013 |
Hoang ML, Chen CH, Sidorenko VS, He J, Dickman KG, Yun BH, Moriya M, Niknafs N, Douville C, Karchin R, Turesky RJ, Pu YS, Vogelstein B, Papadopoulos N, Grollman AP, ... Kinzler KW, et al. Mutational signature of aristolochic acid exposure as revealed by whole-exome sequencing Science Translational Medicine. 5. PMID 23926200 DOI: 10.1126/Scitranslmed.3006200 |
0.399 |
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| 2013 |
He J, Wu J, Jiao Y, Rodriguez FJ, Blakeley JO, Kinzler KW, Papadopoulos N, Vogelstein B, Holdhoff M. Limited detection of IgH gene rearrangements in plasma of patients with primary central nervous system lymphoma. Journal of Neuro-Oncology. 114: 275-9. PMID 23828278 DOI: 10.1007/S11060-013-1182-7 |
0.304 |
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| 2013 |
Bettegowda C, Agrawal N, Jiao Y, Wang Y, Wood LD, Rodriguez FJ, Hruban RH, Gallia GL, Binder ZA, Riggins CJ, Salmasi V, Riggins GJ, Reitman ZJ, Rasheed A, Keir S, ... ... Kinzler KW, et al. Exomic sequencing of four rare central nervous system tumor types. Oncotarget. 4: 572-83. PMID 23592488 DOI: 10.18632/Oncotarget.964 |
0.583 |
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| 2013 |
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA, Kinzler KW. Cancer genome landscapes. Science (New York, N.Y.). 339: 1546-58. PMID 23539594 DOI: 10.1126/Science.1235122 |
0.471 |
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| 2013 |
Killela PJ, Reitman ZJ, Jiao Y, Bettegowda C, Agrawal N, Diaz LA, Friedman AH, Friedman H, Gallia GL, Giovanella BC, Grollman AP, He TC, He Y, Hruban RH, Jallo GI, ... ... Kinzler KW, et al. TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. Proceedings of the National Academy of Sciences of the United States of America. 110: 6021-6. PMID 23530248 DOI: 10.1093/Neuonc/Nou206.18 |
0.597 |
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| 2013 |
Kinde I, Bettegowda C, Wang Y, Wu J, Agrawal N, Shih IeM, Kurman R, Dao F, Levine DA, Giuntoli R, Roden R, Eshleman JR, Carvalho JP, Marie SK, Papadopoulos N, ... Kinzler KW, et al. Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers. Science Translational Medicine. 5: 167ra4. PMID 23303603 DOI: 10.1126/Scitranslmed.3004952 |
0.625 |
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| 2013 |
Agrawal N, Jiao Y, Sausen M, Leary R, Bettegowda C, Roberts NJ, Bhan S, Ho AS, Khan Z, Bishop J, Westra WH, Wood LD, Hruban RH, Tufano RP, Robinson B, ... ... Kinzler KW, et al. Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS. The Journal of Clinical Endocrinology and Metabolism. 98: E364-9. PMID 23264394 DOI: 10.1210/Jc.2012-2703 |
0.59 |
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| 2013 |
Vogelstein B, Kinzler KW. Abstract DL01-01: Cancer Genomes and their Implications for Early Detection Cancer Prevention Research. 6. DOI: 10.1158/1940-6215.Prev-13-Dl01-01 |
0.399 |
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| 2012 |
Leary RJ, Sausen M, Kinde I, Papadopoulos N, Carpten JD, Craig D, O'Shaughnessy J, Kinzler KW, Parmigiani G, Vogelstein B, Diaz LA, Velculescu VE. Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing. Science Translational Medicine. 4: 162ra154. PMID 23197571 DOI: 10.1126/Scitranslmed.3004742 |
0.434 |
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| 2012 |
Matthaei H, Wu J, Dal Molin M, Debeljak M, Lingohr P, Katabi N, Klimstra DS, Adsay NV, Eshleman JR, Schulick RD, Kinzler KW, Vogelstein B, Hruban RH, Maitra A. GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct Hpb. 14: 677-682. PMID 22954004 DOI: 10.1055/S-0032-1324039 |
0.336 |
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| 2012 |
Agrawal N, Jiao Y, Bettegowda C, Hutfless SM, Wang Y, David S, Cheng Y, Twaddell WS, Latt NL, Shin EJ, Wang LD, Wang L, Yang W, Velculescu VE, Vogelstein B, ... ... Kinzler KW, et al. Comparative genomic analysis of esophageal adenocarcinoma and squamous cell carcinoma. Cancer Discovery. 2: 899-905. PMID 22877736 DOI: 10.1158/2159-8290.Cd-12-0189 |
0.576 |
|
| 2012 |
Jiao Y, Killela PJ, Reitman ZJ, Rasheed AB, Heaphy CM, de Wilde RF, Rodriguez FJ, Rosemberg S, Oba-Shinjo SM, Nagahashi Marie SK, Bettegowda C, Agrawal N, Lipp E, Pirozzi C, Lopez G, ... ... Kinzler KW, et al. Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas. Oncotarget. 3: 709-22. PMID 22869205 DOI: 10.18632/Oncotarget.588 |
0.571 |
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| 2012 |
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, ... ... Kinzler K, et al. Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. Plos Genetics. 8: e1002772. PMID 22829774 DOI: 10.1371/Journal.Pgen.1002772 |
0.433 |
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| 2012 |
Cui Y, Brosnan JA, Blackford AL, Sur S, Hruban RH, Kinzler KW, Vogelstein B, Maitra A, Diaz LA, Iacobuzio-Donahue CA, Eshleman JR. Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6519-30. PMID 22753594 DOI: 10.1158/1078-0432.Ccr-12-0827 |
0.367 |
|
| 2012 |
Diaz LA, Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, Allen B, Bozic I, Reiter JG, Nowak MA, Kinzler KW, Oliner KS, Vogelstein B. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature. 486: 537-40. PMID 22722843 DOI: 10.1038/Nature11219 |
0.362 |
|
| 2012 |
Roberts NJ, Jiao Y, Yu J, Kopelovich L, Petersen GM, Bondy ML, Gallinger S, Schwartz AG, Syngal S, Cote ML, Axilbund J, Schulick R, Ali SZ, Eshleman JR, Velculescu VE, ... ... Kinzler KW, et al. ATM mutations in patients with hereditary pancreatic cancer Cancer Discovery. 2: 41-46. PMID 22585167 DOI: 10.1158/2159-8290.Cd-11-0194 |
0.408 |
|
| 2012 |
Willard MD, Lajiness ME, Wulur IH, Feng B, Swearingen ML, Uhlik MT, Kinzler KW, Velculescu VE, Sjöblom T, Markowitz SD, Powell SM, Vogelstein B, Barber TD. Somatic mutations in CCK2R alter receptor activity that promote oncogenic phenotypes. Molecular Cancer Research : McR. 10: 739-49. PMID 22516348 DOI: 10.1158/1541-7786.Mcr-11-0483 |
0.378 |
|
| 2012 |
Jones S, Wang TL, Kurman RJ, Nakayama K, Velculescu VE, Vogelstein B, Kinzler KW, Papadopoulos N, Shih IM. Low-grade serous carcinomas of the ovary contain very few point mutations Journal of Pathology. 226: 413-420. PMID 22102435 DOI: 10.1002/Path.3967 |
0.352 |
|
| 2012 |
Ahlquist DA, Zou H, Domanico M, Mahoney DW, Yab TC, Taylor WR, Butz ML, Thibodeau SN, Rabeneck L, Paszat LF, Kinzler KW, Vogelstein B, Bjerregaard NC, Laurberg S, Sørensen HT, et al. Next-generation stool DNA test accurately detects colorectal cancer and large adenomas. Gastroenterology. 142: 248-56; quiz e25-6. PMID 22062357 DOI: 10.1053/J.Gastro.2011.10.031 |
0.306 |
|
| 2012 |
Jones S, Li M, Williams Parsons D, Zhang X, Wesseling J, Kristel P, Schmidt MK, Markowitz S, Yan H, Bigner D, Hruban RH, Eshleman JR, Iacobuzio-Donahue CA, Goggins M, Maitra A, ... ... Kinzler KW, et al. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types Human Mutation. 33: 100-103. PMID 22009941 DOI: 10.1002/Humu.21633 |
0.641 |
|
| 2012 |
Roberts NJ, Jiao Y, Yu J, Kopelovich L, Petersen GM, Bondy M, Gallinger S, Schwartz AG, Syngal S, Cote ML, Axilbund J, Schulick R, Ali SZ, Eshleman JR, Velculescu V, ... ... Kinzler KW, et al. Abstract 2628: Genome-wide sequencing identifiesATMas a pancreatic cancer susceptibility gene Cancer Research. 72: 2628-2628. DOI: 10.1158/1538-7445.Am2012-2628 |
0.402 |
|
| 2011 |
Diaz LA, Jiao Y, Shi C, Edil BH, de Wilde R, Klimstra DS, Maitra A, Tang LH, Blackford AL, Velculescu V, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N. Exomic sequencing of pancreatic neuroendocrine tumors: Detection of alterations in chromatin remodeling and mTOR pathway genes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 10501. PMID 28022366 DOI: 10.1200/Jco.2011.29.15_Suppl.10501 |
0.375 |
|
| 2011 |
Wu J, Jiao Y, Dal Molin M, Maitra A, de Wilde RF, Wood LD, Eshleman JR, Goggins MG, Wolfgang CL, Canto MI, Schulick RD, Edil BH, Choti MA, Adsay V, Klimstra DS, ... ... Kinzler KW, et al. Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways. Proceedings of the National Academy of Sciences of the United States of America. 108: 21188-93. PMID 22158988 DOI: 10.1073/Pnas.1118046108 |
0.435 |
|
| 2011 |
Li M, Collins R, Jiao Y, Ouillette P, Bixby D, Erba H, Vogelstein B, Kinzler KW, Papadopoulos N, Malek SN. Somatic mutations in the transcriptional corepressor gene BCORL1 in adult acute myelogenous leukemia Blood. 118: 5914-5917. PMID 21989985 DOI: 10.1182/Blood-2011-05-356204 |
0.399 |
|
| 2011 |
Li M, Zhao H, Zhang X, Wood LD, Anders RA, Choti MA, Pawlik TM, Daniel HD, Kannangai R, Offerhaus GJ, Velculescu VE, Wang L, Zhou S, Vogelstein B, Hruban RH, ... ... Kinzler KW, et al. Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma. Nature Genetics. 43: 828-9. PMID 21822264 DOI: 10.1038/Ng.903 |
0.489 |
|
| 2011 |
Bettegowda C, Agrawal N, Jiao Y, Sausen M, Wood LD, Hruban RH, Rodriguez FJ, Cahill DP, McLendon R, Riggins G, Velculescu VE, Oba-Shinjo SM, Marie SK, Vogelstein B, Bigner D, ... ... Kinzler KW, et al. Mutations in CIC and FUBP1 contribute to human oligodendroglioma. Science (New York, N.Y.). 333: 1453-5. PMID 21817013 DOI: 10.1126/Science.1210557 |
0.547 |
|
| 2011 |
Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Treviño L, ... ... Kinzler KW, et al. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science (New York, N.Y.). 333: 1154-7. PMID 21798897 DOI: 10.1126/Science.1206923 |
0.565 |
|
| 2011 |
Wu J, Matthaei H, Maitra A, Dal Molin M, Wood LD, Eshleman JR, Goggins M, Canto MI, Schulick RD, Edil BH, Wolfgang CL, Klein AP, Diaz LA, Allen PJ, Schmidt CM, ... Kinzler KW, et al. Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development. Science Translational Medicine. 3: 92ra66. PMID 21775669 DOI: 10.1126/Scitranslmed.3002543 |
0.365 |
|
| 2011 |
Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, ... ... Kinzler KW, et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science (New York, N.Y.). 333: 425. PMID 21719641 DOI: 10.1126/Science.1207313 |
0.597 |
|
| 2011 |
Zhang X, Reis M, Khoriaty R, Li Y, Ouillette P, Samayoa J, Carter H, Karchin R, Li M, Diaz LA, Velculescu VE, Papadopoulos N, Kinzler KW, Vogelstein B, Malek SN. Sequence analysis of 515 kinase genes in chronic lymphocytic leukemia. Leukemia. 25: 1908-10. PMID 21701494 DOI: 10.1038/Leu.2011.163 |
0.615 |
|
| 2011 |
Holdhoff M, Schmidt K, Diehl F, Aggrawal N, Angenendt P, Romans K, Edelstein DL, Torbenson M, Kinzler KW, Vogelstein B, Choti MA, Diaz LA. Detection of tumor DNA at the margins of colorectal cancer liver metastasis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 3551-7. PMID 21531819 DOI: 10.1158/1078-0432.Ccr-10-3087 |
0.406 |
|
| 2011 |
He J, Wu J, Jiao Y, Wagner-Johnston N, Ambinder RF, Diaz LA, Kinzler KW, Vogelstein B, Papadopoulos N. IgH gene rearrangements as plasma biomarkers in Non- Hodgkin's lymphoma patients. Oncotarget. 2: 178-85. PMID 21399237 DOI: 10.18632/Oncotarget.235 |
0.339 |
|
| 2011 |
Qiao Y, Huang X, Nimmagadda S, Bai R, Staedtke V, Foss CA, Cheong I, Holdhoff M, Kato Y, Pomper MG, Riggins GJ, Kinzler KW, Diaz LA, Vogelstein B, Zhou S. A robust approach to enhance tumor-selective accumulation of nanoparticles. Oncotarget. 2: 59-68. PMID 21378416 DOI: 10.18632/Oncotarget.227 |
0.31 |
|
| 2011 |
Reitman ZJ, Jin G, Karoly ED, Spasojevic I, Yang J, Kinzler KW, He Y, Bigner DD, Vogelstein B, Yan H. Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proceedings of the National Academy of Sciences of the United States of America. 108: 3270-5. PMID 21289278 DOI: 10.1073/Pnas.1019393108 |
0.367 |
|
| 2011 |
Jiao Y, Shi C, Edil BH, de Wilde RF, Klimstra DS, Maitra A, Schulick RD, Tang LH, Wolfgang CL, Choti MA, Velculescu VE, Diaz LA, Vogelstein B, Kinzler KW, Hruban RH, et al. DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science (New York, N.Y.). 331: 1199-203. PMID 21252315 DOI: 10.1126/Science.1200609 |
0.325 |
|
| 2011 |
Parsons DW, Li M, Zhang X, Jones S, Leary RJ, Lin JC, Boca SM, Carter H, Samayoa J, Bettegowda C, Gallia GL, Jallo GI, Binder ZA, Nikolsky Y, Hartigan J, ... ... Kinzler KW, et al. The genetic landscape of the childhood cancer medulloblastoma. Science (New York, N.Y.). 331: 435-9. PMID 21163964 DOI: 10.1126/Science.1198056 |
0.701 |
|
| 2011 |
Guerrero-Preston R, Agrawal N, Sidransky D, Li RJ, Westra WH, Koch WM, Califano JA, Vogelstein B, Velculescu VE, Papadopoulos N, Kinzler KW. Abstract PR3: Exome sequencing of head and neck squamous cell carcinoma reveals a higher frequency of mutations in TP53 among African Americans Cancer Epidemiology, Biomarkers & Prevention. 20. DOI: 10.1158/1055-9965.Disp-11-Pr3 |
0.405 |
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| 2010 |
Schmidt-Kittler O, Zhu J, Yang J, Liu G, Hendricks W, Lengauer C, Gabelli SB, Kinzler KW, Vogelstein B, Huso DL, Zhou S. PI3Kα inhibitors that inhibit metastasis. Oncotarget. 1: 339-348. PMID 21179398 DOI: 10.18632/Oncotarget.166 |
0.627 |
|
| 2010 |
Boca SM, Kinzler KW, Velculescu VE, Vogelstein B, Parmigiani G. Patient-oriented gene set analysis for cancer mutation data Genome Biology. 11. PMID 21092299 DOI: 10.1186/Gb-2010-11-11-R112 |
0.398 |
|
| 2010 |
Yachida S, Jones S, Bozic I, Antal T, Leary R, Fu B, Kamiyama M, Hruban RH, Eshleman JR, Nowak MA, Velculescu VE, Kinzler KW, Vogelstein B, Iacobuzio-Donahue CA. Distant metastasis occurs late during the genetic evolution of pancreatic cancer Nature. 467: 1114-1117. PMID 20981102 DOI: 10.1038/Nature09515 |
0.387 |
|
| 2010 |
Bozic I, Antal T, Ohtsuki H, Carter H, Kim D, Chen S, Karchin R, Kinzler KW, Vogelstein B, Nowak MA. Accumulation of driver and passenger mutations during tumor progression Proceedings of the National Academy of Sciences of the United States of America. 107: 18545-18550. PMID 20876136 DOI: 10.1073/Pnas.1010978107 |
0.422 |
|
| 2010 |
Jones S, Wang TL, Shih IeM, Mao TL, Nakayama K, Roden R, Glas R, Slamon D, Diaz LA, Vogelstein B, Kinzler KW, Velculescu VE, Papadopoulos N. Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science (New York, N.Y.). 330: 228-31. PMID 20826764 DOI: 10.1126/Science.1196333 |
0.47 |
|
| 2010 |
Leary RJ, Kinde I, Diehl F, Schmidt K, Clouser C, Duncan C, Antipova A, Lee C, McKernan K, De La Vega FM, Kinzler KW, Vogelstein B, Diaz LA, Velculescu VE. Development of personalized tumor biomarkers using massively parallel sequencing. Science Translational Medicine. 2: 20ra14. PMID 20371490 DOI: 10.1126/Scitranslmed.3000702 |
0.425 |
|
| 2010 |
Ericson K, Gan C, Cheong I, Rago C, Samuels Y, Velculescu VE, Kinzler KW, Huso DL, Vogelstein B, Papadopoulos N. Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation. Proceedings of the National Academy of Sciences of the United States of America. 107: 2598-603. PMID 20133737 DOI: 10.1073/Pnas.0914018107 |
0.37 |
|
| 2010 |
Schmidt K, Holdhoff M, Diehl F, Angenendt P, Agrawal N, Judge K, Kinzler KW, Vogelstein B, Choti MA, Diaz LA. Mutation-based detection of molecular tumor margins in colorectal liver metastasis. Journal of Clinical Oncology. 28: 3610-3610. DOI: 10.1200/Jco.2010.28.15_Suppl.3610 |
0.386 |
|
| 2010 |
Zhang X, Li M, Ouillette P, Diaz L, Reis M, Velculescu V, Kinzler K, Malek S, Vogelstein B. Identification of Somatically Acquired Gene Mutations In the Kineome and Exome In CLL Blood. 116: 2410-2410. DOI: 10.1182/Blood.V116.21.2410.2410 |
0.631 |
|
| 2010 |
Ericson K, Gan C, Cheong I, Rago C, Samuels Y, Velculescu VE, Kinzler KW, Huso DL, Vogelstein B, Papadopoulos N. Genetic inactivation of AKT1, AKT2, and PDPK1 in human colorectal cancer cells clarifies their roles in tumor growth regulation (Proceedings of the National Academy of Sciences of the United States of America (2010) 107 (2598-2603) DOI: 10.1073/pnas.0914018107) Proceedings of the National Academy of Sciences of the United States of America. 107: 6551. DOI: 10.1073/Pnas.1002415107 |
0.379 |
|
| 2009 |
Mandelker D, Gabelli SB, Schmidt-Kittler O, Zhu J, Cheong I, Huang CH, Kinzler KW, Vogelstein B, Amzel LM. A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane Proceedings of the National Academy of Sciences of the United States of America. 106: 16996-17001. PMID 19805105 DOI: 10.1073/Pnas.0908444106 |
0.61 |
|
| 2009 |
Yun J, Rago C, Cheong I, Pagliarini R, Angenendt P, Rajagopalan H, Schmidt K, Willson JK, Markowitz S, Zhou S, Diaz LA, Velculescu VE, Lengauer C, Kinzler KW, Vogelstein B, et al. Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Science (New York, N.Y.). 325: 1555-9. PMID 19661383 DOI: 10.1126/Science.1174229 |
0.387 |
|
| 2009 |
Carter H, Chen S, Isik L, Tyekucheva S, Velculescu VE, Kinzler KW, Vogelstein B, Karchin R. Cancer-specific high-throughput annotation of somatic mutations: Computational prediction of driver missense mutations Cancer Research. 69: 6660-6667. PMID 19654296 DOI: 10.1158/0008-5472.Can-09-1133 |
0.386 |
|
| 2009 |
Guda K, Moinova H, He J, Jamison O, Ravi L, Natale L, Lutterbaugh J, Lawrence E, Lewis S, Willson JKV, Lowe JB, Wiesner GL, Parmigiani G, Barnholtz-Sloan J, Dawson DW, ... ... Kinzler KW, et al. Inactivating germ-line and somatic mutations in polypeptide N-acetylgalactosaminyltransferase 12 in human colon cancers Proceedings of the National Academy of Sciences of the United States of America. 106: 12921-12925. PMID 19617566 DOI: 10.1073/Pnas.0901454106 |
0.442 |
|
| 2009 |
Blackford A, Serrano OK, Wolfgang CL, Parmigiani G, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Cameron JL, ... ... Kinzler KW, et al. SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4674-9. PMID 19584151 DOI: 10.1158/1078-0432.Ccr-09-0227 |
0.646 |
|
| 2009 |
Duncan CG, Leary RJ, Lin JC, Cummins J, Di C, Schaefer CF, Wang TL, Riggins GJ, Edwards J, Bigner D, Kopelovich L, Vogelstein B, Kinzler KW, Velculescu VE, Yan H. Identification of microbial DNA in human cancer. Bmc Medical Genomics. 2: 22. PMID 19426505 DOI: 10.1186/1755-8794-2-22 |
0.374 |
|
| 2009 |
Blackford A, Parmigiani G, Kensler TW, Wolfgang C, Jones S, Zhang X, Parsons DW, Lin JCH, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Klein A, ... ... Kinzler KW, et al. Genetic mutations associated with Cigarette smoking in pancreatic cancer Cancer Research. 69: 3681-3688. PMID 19351817 DOI: 10.1158/0008-5472.Can-09-0015 |
0.603 |
|
| 2009 |
Jones S, Hruban RH, Kamiyama M, Borges M, Zhang X, Parsons DW, Lin JCH, Palmisano E, Brune K, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Parmigiani G, Kern SE, Velculescu VE, ... Kinzler KW, et al. Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene Science. 324: 217. PMID 19264984 DOI: 10.1126/Science.1171202 |
0.632 |
|
| 2009 |
Yan H, Parsons DW, Jin G, McLendon R, Rasheed BA, Yuan W, Kos I, Batinic-Haberle I, Jones S, Riggins GJ, Friedman H, Friedman A, Reardon D, Herndon J, Kinzler KW, et al. IDH1 and IDH2 mutations in gliomas. The New England Journal of Medicine. 360: 765-73. PMID 19228619 DOI: 10.1056/Nejmoa0808710 |
0.31 |
|
| 2009 |
Sur S, Pagliarini R, Bunz F, Rago C, Diaz LA, Kinzler KW, Vogelstein B, Papadopoulos N. A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53. Proceedings of the National Academy of Sciences of the United States of America. 106: 3964-9. PMID 19225112 DOI: 10.1073/Pnas.0813333106 |
0.418 |
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| 2009 |
Parmigiani G, Boca S, Lin J, Kinzler KW, Velculescu V, Vogelstein B. Design and analysis issues in genome-wide somatic mutation studies of cancer Genomics. 93: 17-21. PMID 18692126 DOI: 10.1016/J.Ygeno.2008.07.005 |
0.318 |
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| 2008 |
Diehl F, Schmidt K, Choti MA, Goodman S, Romans K, Thornton K, Kinzler K, Vogelstein B, Diaz LA. Circulating tumor DNA as a cancer biomarker. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 4122. PMID 27950955 DOI: 10.1200/Jco.2008.26.15_Suppl.4122 |
0.443 |
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| 2008 |
Leary RJ, Lin JC, Cummins J, Boca S, Wood LD, Parsons DW, Jones S, Sjöblom T, Park BH, Parsons R, Willis J, Dawson D, Willson JK, Nikolskaya T, Nikolsky Y, ... ... Kinzler KW, et al. Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 105: 16224-9. PMID 18852474 DOI: 10.1073/Pnas.0808041105 |
0.431 |
|
| 2008 |
Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Jimeno A, Hong SM, Fu B, Lin MT, Calhoun ES, Kamiyama M, ... ... Kinzler KW, et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science (New York, N.Y.). 321: 1801-6. PMID 18772397 DOI: 10.1126/Science.1164368 |
0.599 |
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| 2008 |
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, ... ... Kinzler KW, et al. An integrated genomic analysis of human glioblastoma multiforme. Science (New York, N.Y.). 321: 1807-12. PMID 18772396 DOI: 10.1126/Science.1164382 |
0.611 |
|
| 2008 |
Jones S, Chen WD, Parmigiani G, Diehl F, Beerenwinkel N, Antal T, Traulsen A, Nowak MA, Siegel C, Velculescu VE, Kinzler KW, Vogelstein B, Willis J, Markowitz SD. Comparative lesion sequencing provides insights into tumor evolution. Proceedings of the National Academy of Sciences of the United States of America. 105: 4283-8. PMID 18337506 DOI: 10.1073/Pnas.0712345105 |
0.463 |
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| 2008 |
Barber TD, McManus K, Yuen KW, Reis M, Parmigiani G, Shen D, Barrett I, Nouhi Y, Spencer F, Markowitz S, Velculescu VE, Kinzler KW, Vogelstein B, Lengauer C, Hieter P. Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 105: 3443-8. PMID 18299561 DOI: 10.1073/Pnas.0712384105 |
0.426 |
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| 2008 |
Segal NH, Parsons DW, Peggs KS, Velculescu V, Kinzler KW, Vogelstein B, Allison JP. Epitope landscape in breast and colorectal cancer Cancer Research. 68: 889-892. PMID 18245491 DOI: 10.1158/0008-5472.Can-07-3095 |
0.445 |
|
| 2007 |
Huang CH, Mandelker D, Schmidt-Kittler O, Samuels Y, Velculescu VE, Kinzler KW, Vogelstein B, Gabelli SB, Amzel LM. The structure of a human p110α/p85α complex elucidates the effects of oncogenic PI3Kα mutations Science. 318: 1744-1748. PMID 18079394 DOI: 10.1126/Science.1150799 |
0.617 |
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| 2007 |
Beerenwinkel N, Antal T, Dingli D, Traulsen A, Kinzler KW, Velculescu VE, Vogelstein B, Nowak MA. Genetic progression and the waiting time to cancer. Plos Computational Biology. 3: e225. PMID 17997597 DOI: 10.1371/Journal.Pcbi.0030225 |
0.422 |
|
| 2007 |
Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, ... ... Kinzler KW, et al. The genomic landscapes of human breast and colorectal cancers. Science (New York, N.Y.). 318: 1108-13. PMID 17932254 DOI: 10.1126/science.1145720 |
0.366 |
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| 2007 |
Diaz LA, Foss CA, Thornton K, Nimmagadda S, Endres CJ, Uzuner O, Seyler TM, Ulrich SD, Conway J, Bettegowda C, Agrawal N, Cheong I, Zhang X, Ladenson PW, Vogelstein BN, ... ... Kinzler KW, et al. Imaging of musculoskeletal bacterial infections by [124I]FIAU-PET/CT. Plos One. 2: e1007. PMID 17925855 DOI: 10.1371/Journal.Pone.0001007 |
0.609 |
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| 2007 |
Rago C, Huso DL, Diehl F, Karim B, Liu G, Papadopoulos N, Samuels Y, Velculescu VE, Vogelstein B, Kinzler KW, Diaz LA. Serial assessment of human tumor burdens in mice by the analysis of circulating DNA. Cancer Research. 67: 9364-70. PMID 17909045 DOI: 10.1158/0008-5472.Can-07-0605 |
0.355 |
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| 2007 |
Lin J, Gan CM, Zhang X, Jones S, Sjöblom T, Wood LD, Parsons DW, Papadopoulos N, Kinzler KW, Vogelstein B, Parmigiani G, Velculescu VE. A multidimensional analysis of genes mutated in breast and colorectal cancers Genome Research. 17: 1304-1318. PMID 17693572 DOI: 10.1101/Gr.6431107 |
0.638 |
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| 2007 |
Plomp M, McCaffery JM, Cheong I, Huang X, Bettegowda C, Kinzler KW, Zhou S, Vogelstein B, Malkin AJ. Spore coat architecture of Clostridium novyi NT spores. Journal of Bacteriology. 189: 6457-68. PMID 17586633 DOI: 10.1128/Jb.00757-07 |
0.465 |
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| 2007 |
Zhang X, Guo A, Yu J, Possemato A, Chen Y, Zheng W, Polakiewicz RD, Kinzler KW, Vogelstein B, Velculescu VE, Wang ZJ. Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T. Proceedings of the National Academy of Sciences of the United States of America. 104: 4060-4. PMID 17360477 DOI: 10.1073/Pnas.0611665104 |
0.592 |
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| 2007 |
Lagerstedt Robinson K, Liu T, Vandrovcova J, Halvarsson B, Clendenning M, Frebourg T, Papadopoulos N, Kinzler KW, Vogelstein B, Peltomäki P, Kolodner RD, Nilbert M, Lindblom A. Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics Journal of the National Cancer Institute. 99: 291-299. PMID 17312306 DOI: 10.1093/Jnci/Djk051 |
0.42 |
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| 2007 |
Peters BA, St Croix B, Sjöblom T, Cummins JM, Silliman N, Ptak J, Saha S, Kinzler KW, Hatzis C, Velculescu VE. Large-scale identification of novel transcripts in the human genome. Genome Research. 17: 287-92. PMID 17267814 DOI: 10.1101/Gr.5486607 |
0.779 |
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| 2007 |
Parmigiani G, Lin J, Boca SM, Sjöblom T, Jones S, Wood LD, Parsons DW, Barber T, Buckhaults P, Markowitz SD, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, et al. Response to comments on "The consensus coding sequences of human breast and colorectal cancers" Science. 317: 1500d. DOI: 10.1126/Science.1138773 |
0.333 |
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| 2006 |
Cheong I, Huang X, Bettegowda C, Diaz LA, Kinzler KW, Zhou S, Vogelstein B. A bacterial protein enhances the release and efficacy of liposomal cancer drugs Science. 314: 1308-1311. PMID 17124324 DOI: 10.1126/Science.1130651 |
0.547 |
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| 2006 |
Bettegowda C, Huang X, Lin J, Cheong I, Kohli M, Szabo SA, Zhang X, Diaz LA, Velculescu VE, Parmigiani G, Kinzler KW, Vogelstein B, Zhou S. The genome and transcriptomes of the anti-tumor agent Clostridium novyi-NT Nature Biotechnology. 24: 1573-1580. PMID 17115055 DOI: 10.1038/Nbt1256 |
0.691 |
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| 2006 |
Chen S, Wang W, Lee S, Nafa K, Lee J, Romans K, Watson P, Gruber SB, Euhus D, Kinzler KW, Jass J, Gallinger S, Lindor NM, Casey G, Ellis N, et al. Prediction of germline mutations and cancer risk in the Lynch syndrome. Jama. 296: 1479-87. PMID 17003396 DOI: 10.1001/Jama.296.12.1479 |
0.352 |
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| 2006 |
Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, ... ... Kinzler KW, et al. The consensus coding sequences of human breast and colorectal cancers Science. 314: 268-274. PMID 16959974 DOI: 10.1126/science.1133427 |
0.371 |
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| 2006 |
Wood LD, Calhoun ES, Silliman N, Ptak J, Szabo S, Powell SM, Riggins GJ, Wang TL, Yan H, Gazdar A, Kern SE, Pennacchio L, Kinzler KW, Vogelstein B, Velculescu VE. Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers Human Mutation.. 27: 1060-1061. PMID 16941478 DOI: 10.1002/Humu.9452 |
0.463 |
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| 2006 |
Papadopoulos N, Kinzler KW, Vogelstein B. The role of companion diagnostics in the development and use of mutation-targeted cancer therapies Nature Biotechnology. 24: 985-995. PMID 16900147 DOI: 10.1038/Nbt1234 |
0.408 |
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| 2006 |
Nanda A, Karim B, Peng Z, Liu G, Qiu W, Gan C, Vogelstein B, Croix BS, Kinzler KW, Huso DL. Tumor endothelial marker 1 (Tem1) functions in the growth and progression of abdominal tumors Proceedings of the National Academy of Sciences of the United States of America. 103: 3351-3356. PMID 16492758 DOI: 10.1073/Pnas.0511306103 |
0.734 |
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| 2005 |
Diehl F, Li M, Dressman D, He Y, Shen D, Szabo S, Diaz LA, Goodman SN, David KA, Juhl H, Kinzler KW, Vogelstein B. Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proceedings of the National Academy of Sciences of the United States of America. 102: 16368-73. PMID 16258065 DOI: 10.1073/Pnas.0507904102 |
0.398 |
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| 2005 |
Diaz LA, Cheong I, Foss CA, Zhang X, Peters BA, Agrawal N, Bettegowda C, Karim B, Liu G, Khan K, Huang X, Kohli M, Dang LH, Hwang P, Vogelstein A, ... ... Kinzler KW, et al. Pharmacologic and toxicologic evaluation of C. novyi-NT spores. Toxicological Sciences : An Official Journal of the Society of Toxicology. 88: 562-75. PMID 16162850 DOI: 10.1093/Toxsci/Kfi316 |
0.767 |
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| 2005 |
Parsons DW, Wang TL, Samuels Y, Bardelli A, Cummins JM, DeLong L, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz S, Kinzler KW, Vogelstein B, Lengauer C, Velculescu VE. Colorectal cancer: mutations in a signalling pathway. Nature. 436: 792. PMID 16094359 DOI: 10.1038/436792A |
0.391 |
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| 2005 |
Smith AB, Freeze BS, LaMarche MJ, Sager J, Kinzler KW, Vogelstein B. Discodermolide analogues as the chemical component of combination bacteriolytic therapy. Bioorganic & Medicinal Chemistry Letters. 15: 3623-6. PMID 15979874 DOI: 10.1016/J.Bmcl.2005.05.068 |
0.376 |
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| 2005 |
Bachman KE, Sager J, Cheong I, Catto M, Bardelli A, Park BH, Vogelstein B, Carotti A, Kinzler KW, Lengauer C. Identification of compounds that inhibit growth of 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine-resistant cancer cells Molecular Cancer Therapeutics. 4: 1026-1030. PMID 15956261 DOI: 10.1158/1535-7163.Mct-05-0038 |
0.339 |
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| 2005 |
Samuels Y, Diaz LA, Schmidt-Kittler O, Cummins JM, Delong L, Cheong I, Rago C, Huso DL, Lengauer C, Kinzler KW, Vogelstein B, Velculescu VE. Mutant PIK3CA promotes cell growth and invasion of human cancer cells. Cancer Cell. 7: 561-73. PMID 15950905 DOI: 10.1016/J.Ccr.2005.05.014 |
0.434 |
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| 2005 |
Peters BA, Diaz LA, Polyak K, Meszler L, Romans K, Guinan EC, Antin JH, Myerson D, Hamilton SR, Vogelstein B, Kinzler KW, Lengauer C. Contribution of bone marrow-derived endothelial cells to human tumor vasculature Nature Medicine. 11: 261-262. PMID 15723071 DOI: 10.1038/Nm1200 |
0.694 |
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| 2005 |
Bettegowda C, Foss CA, Cheong I, Wang Y, Diaz L, Agrawal N, Fox J, Dick J, Dang LH, Zhou S, Kinzler KW, Vogelstein B, Pomper MG. Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil. Proceedings of the National Academy of Sciences of the United States of America. 102: 1145-50. PMID 15653773 DOI: 10.1073/Pnas.0408861102 |
0.47 |
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| 2004 |
Barber TD, Vogelstein B, Kinzler KW, Velculescu VE. Somatic mutations of EGFR in colorectal cancers and glioblastomas [6] New England Journal of Medicine. 351: 2883. PMID 15625347 DOI: 10.1056/Nejm200412303512724 |
0.391 |
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| 2004 |
Nanda A, Buckhaults P, Seaman S, Agrawal N, Boutin P, Shankara S, Nacht M, Teicher B, Stampfl J, Singh S, Vogelstein B, Kinzler KW, St Croix B. Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R. Cancer Research. 64: 8507-11. PMID 15574754 DOI: 10.1158/0008-5472.Can-04-2716 |
0.729 |
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| 2004 |
Kohli M, Yu J, Seaman C, Bardelli A, Kinzler KW, Vogelstein B, Lengauer C, Zhang L. SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells Proceedings of the National Academy of Sciences of the United States of America. 101: 16897-16902. PMID 15557007 DOI: 10.1073/Pnas.0403405101 |
0.304 |
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| 2004 |
Agrawal N, Bettegowda C, Cheong I, Geschwind JF, Drake CG, Hipkiss EL, Tatsumi M, Dang LH, Diaz LA, Pomper M, Abusedera M, Wahl RL, Kinzler KW, Zhou S, Huso DL, et al. Bacteriolytic therapy can generate a potent immune response against experimental tumors Proceedings of the National Academy of Sciences of the United States of America. 101: 15172-15177. PMID 15471990 DOI: 10.1073/Pnas.0406242101 |
0.565 |
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| 2004 |
Vogelstein B, Kinzler KW. Cancer genes and the pathways they control Nature Medicine. 10: 789-799. PMID 15286780 DOI: 10.1038/Nm1087 |
0.407 |
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| 2004 |
Wang Z, Shen D, Parsons DW, Bardelli A, Sager J, Szabo S, Ptak J, Silliman N, Peters BA, van der Heijden MS, Parmigiani G, Yan H, Wang TL, Riggins G, Powell SM, ... ... Kinzler KW, et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science (New York, N.Y.). 304: 1164-6. PMID 15155950 DOI: 10.1126/Science.1096096 |
0.736 |
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| 2004 |
Cummins JM, Kohli M, Rago C, Kinzler KW, Vogelstein B, Bunz F. X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells. Cancer Research. 64: 3006-8. PMID 15126334 DOI: 10.1158/0008-5472.Can-04-0046 |
0.363 |
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| 2004 |
Wang Z, Cummins JM, Shen D, Cahill DP, Jallepalli PV, Wang TL, Parsons DW, Traverso G, Awad M, Silliman N, Ptak J, Szabo S, Willson JK, Markowitz SD, Goldberg ML, ... ... Kinzler KW, et al. Three classes of genes mutated in colorectal cancers with chromosomal instability. Cancer Research. 64: 2998-3001. PMID 15126332 DOI: 10.1158/0008-5472.Can-04-0587 |
0.412 |
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| 2004 |
Koopmann J, Buckhaults P, Brown DA, Zahurak ML, Sato N, Fukushima N, Sokoll LJ, Chan DW, Yeo CJ, Hruban RH, Breit SN, Kinzler KW, Vogelstein B, Goggins M. Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2386-92. PMID 15073115 DOI: 10.1158/1078-0432.Ccr-03-0165 |
0.348 |
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| 2004 |
Wang TL, Diaz LA, Romans K, Bardelli A, Saha S, Galizia G, Choti M, Donehower R, Parmigiani G, Shih IM, Iacobuzio-Donahue C, Kinzler KW, Vogelstein B, Lengauer C, Velculescu VE. Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients Proceedings of the National Academy of Sciences of the United States of America. 101: 3089-3094. PMID 14970324 DOI: 10.1073/Pnas.0308716101 |
0.707 |
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| 2004 |
Nanda A, Carson-Walter EB, Seaman S, Barber TD, Stampfl J, Singh S, Vogelstein B, Kinzler KW, St Croix B. TEM8 interacts with the cleaved C5 domain of collagen alpha 3(VI). Cancer Research. 64: 817-20. PMID 14871805 DOI: 10.1158/0008-5472.Can-03-2408 |
0.711 |
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| 2004 |
Dang LH, Bettegowda C, Agrawal N, Cheong I, Huso D, Frost P, Loganzo F, Greenberger L, Barkoczy J, Pettit GR, Smith AB, Gurulingappa H, Khan S, Parmigiani G, Kinzler KW, et al. Targeting vascular and avascular compartments of tumors with C. novyi-NT and anti-microtubule agents Cancer Biology and Therapy. 3: 326-337. PMID 14739784 DOI: 10.4161/Cbt.3.3.704 |
0.548 |
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| 2004 |
Kohli M, Rago C, Lengauer C, Kinzler KW, Vogelstein B. Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses Nucleic Acids Research. 32: e3. PMID 14704360 DOI: 10.1093/Nar/Gnh009 |
0.369 |
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| 2003 |
Traverso G, Bettegowda C, Kraus J, Speicher MR, Kinzler KW, Vogelstein B, Lengauer C. Hyper-Recombination and Genetic Instability in BLM-Deficient Epithelial Cells Cancer Research. 63: 8578-8581. PMID 14695165 |
0.528 |
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| 2003 |
Bettegowda C, Dang LH, Abrams R, Huso DL, Dillehay L, Cheong I, Agrawal N, Borzillary S, McCaffery JM, Watson EL, Lin KS, Bunz F, Baidoo K, Pomper MG, Kinzler KW, et al. Overcoming the hypoxic barrier to radiation therapy with anaerobic bacteria. Proceedings of the National Academy of Sciences of the United States of America. 100: 15083-8. PMID 14657371 DOI: 10.1073/Pnas.2036598100 |
0.505 |
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| 2003 |
Bardelli A, Saha S, Sager JA, Romans KE, Xin B, Markowitz SD, Lengauer C, Velculescu VE, Kinzler KW, Vogelstein B. PRL-3 Expression in Metastatic Cancers Clinical Cancer Research. 9: 5607-5615. PMID 14654542 |
0.695 |
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| 2003 |
Bardelli A, Parsons DW, Silliman N, Ptak J, Szabo S, Saha S, Markowitz S, Willson JKV, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Mutational analysis of the tyrosine kinome in colorectal cancers Science. 300: 949. PMID 12738854 DOI: 10.1126/Science.1082596 |
0.701 |
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| 2003 |
Yu J, Wang Z, Kinzler KW, Vogelstein B, Zhang L. PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 100: 1931-6. PMID 12574499 DOI: 10.1073/Pnas.2627984100 |
0.352 |
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| 2003 |
Bachman KE, Park BH, Rhee I, Rajagopalan H, Herman JG, Baylin SB, Kinzler KW, Vogelstein B. Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene Cancer Cell. 3: 89-95. PMID 12559178 DOI: 10.1016/S1535-6108(02)00234-9 |
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| 2002 |
Wang TL, Maierhofer C, Speicher MR, Lengauer C, Vogelstein B, Kinzler KW, Velculescu VE. Digital karyotyping. Proceedings of the National Academy of Sciences of the United States of America. 99: 16156-61. PMID 12461184 DOI: 10.1073/Pnas.202610899 |
0.357 |
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| 2002 |
Saha S, Sparks AB, Rago C, Akmaev V, Wang CJ, Vogelstein B, Kinzler KW, Velculescu VE. Using the transcriptome to annotate the genome. Nature Biotechnology. 20: 508-12. PMID 11981567 DOI: 10.1038/Nbt0502-508 |
0.664 |
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| 2002 |
Rhee I, Bachman KE, Park BH, Jair KW, Yen RW, Schuebel KE, Cui H, Feinberg AP, Lengauer C, Kinzler KW, Baylin SB, Vogelstein B. DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature. 416: 552-6. PMID 11932749 DOI: 10.1038/416552A |
0.79 |
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| 2002 |
Wang TL, Rago C, Silliman N, Ptak J, Markowitz S, Willson JK, Parmigiani G, Kinzler KW, Vogelstein B, Velculescu VE. Prevalence of somatic alterations in the colorectal cancer cell genome. Proceedings of the National Academy of Sciences of the United States of America. 99: 3076-80. PMID 11867767 DOI: 10.1073/Pnas.261714699 |
0.48 |
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| 2002 |
Traverso G, Shuber A, Olsson L, Levin B, Johnson C, Hamilton SR, Boynton K, Kinzler KW, Vogelstein B. Detection of proximal colorectal cancers through analysis of faecal DNA. Lancet (London, England). 359: 403-4. PMID 11844514 DOI: 10.1016/S0140-6736(02)07591-8 |
0.398 |
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| 2002 |
Traverso G, Shuber A, Levin B, Johnson C, Olsson L, Schoetz DJ, Hamilton SR, Boynton K, Kinzler KW, Vogelstein B. Detection of APC mutations in fecal DNA from patients with colorectal tumors. The New England Journal of Medicine. 346: 311-20. PMID 11821507 DOI: 10.1056/Nejmoa012294 |
0.303 |
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| 2002 |
Yan H, Dobbie Z, Gruber SB, Markowitz S, Romans K, Giardiello FM, Kinzler KW, Vogelstein B. Small changes in expression affect predisposition to tumorigenesis Nature Genetics. 30: 25-26. PMID 11743581 DOI: 10.1038/Ng799 |
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| 2001 |
Dang LH, Bettegowda C, Huso DL, Kinzler KW, Vogelstein B. Combination bacteriolytic therapy for the treatment of experimental tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 15155-60. PMID 11724950 DOI: 10.1073/Pnas.251543698 |
0.563 |
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| 2001 |
Saha S, Bardelli A, Buckhaults P, Velculescu VE, Rago C, St Croix B, Romans KE, Choti MA, Lengauer C, Kinzler KW, Vogelstein B. A phosphatase associated with metastasis of colorectal cancer. Science (New York, N.Y.). 294: 1343-6. PMID 11598267 DOI: 10.1126/Science.1065817 |
0.734 |
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| 2001 |
Buckhaults P, Rago C, St Croix B, Romans KE, Saha S, Zhang L, Vogelstein B, Kinzler KW. Secreted and cell surface genes expressed in benign and malignant colorectal tumors. Cancer Research. 61: 6996-7001. PMID 11585723 |
0.698 |
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| 2001 |
Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, St Croix B. Cell surface tumor endothelial markers are conserved in mice and humans. Cancer Research. 61: 6649-55. PMID 11559528 |
0.727 |
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| 2001 |
Vogelstein B, Kinzler KW. Achilles' heel of cancer? Nature. 412: 865-6. PMID 11528457 DOI: 10.1038/35091170 |
0.343 |
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| 2001 |
Dong SM, Traverso G, Johnson C, Geng L, Favis R, Boynton K, Hibi K, Goodman SN, D'Allessio M, Paty P, Hamilton SR, Sidransky D, Barany F, Levin B, Shuber A, ... Kinzler KW, et al. Detecting colorectal cancer in stool with the use of multiple genetic targets. Journal of the National Cancer Institute. 93: 858-65. PMID 11390535 DOI: 10.1093/Jnci/93.11.858 |
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| 2001 |
Bardelli A, Cahill DP, Lederer G, Speicher MR, Kinzler KW, Vogelstein B, Lengauer C. Carcinogen-specific induction of genetic instability. Proceedings of the National Academy of Sciences of the United States of America. 98: 5770-5. PMID 11296254 DOI: 10.1073/Pnas.081082898 |
0.325 |
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| 2001 |
Thiagalingam S, Laken S, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B, Lengauer C. Mechanisms underlying losses of heterozygosity in human colorectal cancers. Proceedings of the National Academy of Sciences of the United States of America. 98: 2698-702. PMID 11226302 DOI: 10.1073/Pnas.051625398 |
0.343 |
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| 2001 |
Shih IM, Wang TL, Traverso G, Romans K, Hamilton SR, Ben-Sasson S, Kinzler KW, Vogelstein B. Top-down morphogenesis of colorectal tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 2640-5. PMID 11226292 DOI: 10.1073/Pnas.051629398 |
0.352 |
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| 2001 |
Park BH, Vogelstein B, Kinzler KW. Genetic disruption of PPARδ decreases the tumorigenicity of human colon cancer cells Proceedings of the National Academy of Sciences of the United States of America. 98: 2598-2603. PMID 11226285 DOI: 10.1073/Pnas.051630998 |
0.402 |
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| 2001 |
Zhou W, Galizia G, Lieto E, Goodman SN, Romans KE, Kinzler KW, Vogelstein B, Choti MA, Montgomery EA. Counting alleles reveals a connection between chromosome 18q loss and vascular invasion. Nature Biotechnology. 19: 78-81. PMID 11135558 DOI: 10.1038/83572 |
0.374 |
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| 2001 |
Hwang PM, Bunz F, Yu J, Rago C, Chan TA, Murphy MP, Kelso GF, Smith RAJ, Kinzler KW, Vogelstein B. Erratum: Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells (Nature Medicine (2001) 7 (1111-1117)) Nature Medicine. 7. DOI: 10.1038/Nm1101-1255A |
0.324 |
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| 2000 |
St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW. Genes expressed in human tumor endothelium. Science (New York, N.Y.). 289: 1197-202. PMID 10947988 DOI: 10.1126/Science.289.5482.1197 |
0.385 |
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| 2000 |
Chan TA, Hwang PM, Hermeking H, Kinzler KW, Vogelstein B. Cooperative effects of genes controlling the G(2)/M checkpoint. Genes & Development. 14: 1584-8. PMID 10887152 DOI: 10.1101/Gad.14.13.1584 |
0.327 |
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| 2000 |
Rhee I, Jair KW, Yen RW, Lengauer C, Herman JG, Kinzler KW, Vogelstein B, Baylin SB, Schuebel KE. CpG methylation is maintained in human cancer cells lacking DNMT1. Nature. 404: 1003-7. PMID 10801130 DOI: 10.1038/35010000 |
0.784 |
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| 1999 |
Yu J, Zhang L, Hwang PM, Rago C, Kinzler KW, Vogelstein B. Identification and classification of p53-regulated genes. Proceedings of the National Academy of Sciences of the United States of America. 96: 14517-22. PMID 10588737 DOI: 10.1073/Pnas.96.25.14517 |
0.35 |
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| 1999 |
He TC, Chan TA, Vogelstein B, Kinzler KW. PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell. 99: 335-45. PMID 10555149 DOI: 10.1016/S0092-8674(00)81664-5 |
0.352 |
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| 1999 |
Da Costa LT, He TC, Yu J, Sparks AB, Morin PJ, Polyak K, Laken S, Vogelstein B, Kinzler KW. CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling Oncogene. 18: 5010-5014. PMID 10490837 DOI: 10.1038/Sj.Onc.1202872 |
0.414 |
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| 1999 |
Vogelstein B, Kinzler KW. Digital PCR. Proceedings of the National Academy of Sciences of the United States of America. 96: 9236-41. PMID 10430926 DOI: 10.1073/Pnas.96.16.9236 |
0.357 |
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| 1999 |
Bunz F, Hwang PM, Torrance C, Waldman T, Zhang Y, Dillehay L, Williams J, Lengauer C, Kinzler KW, Vogelstein B. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. The Journal of Clinical Investigation. 104: 263-9. PMID 10430607 DOI: 10.1172/Jci6863 |
0.348 |
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| 1999 |
Cahill DP, da Costa LT, Carson-Walter EB, Kinzler KW, Vogelstein B, Lengauer C. Characterization of MAD2B and other mitotic spindle checkpoint genes. Genomics. 58: 181-7. PMID 10366450 DOI: 10.1006/Geno.1999.5831 |
0.312 |
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| 1999 |
Laken SJ, Papadopoulos N, Petersen GM, Gruber SB, Hamilton SR, Giardiello FM, Brensinger JD, Vogelstein B, Kinzler KW. Analysis of masked mutations in familial adenomatous polyposis Proceedings of the National Academy of Sciences of the United States of America. 96: 2322-2326. PMID 10051640 DOI: 10.1073/Pnas.96.5.2322 |
0.363 |
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| 1999 |
Lengauer C, Kinzler KW, Vogelstein B. Genetic instabilities in human cancers. Nature. 396: 643-9. PMID 9872311 DOI: 10.1038/25292 |
0.341 |
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| 1998 |
Polyak K, Li Y, Zhu H, Lengauer C, Willson JK, Markowitz SD, Trush MA, Kinzler KW, Vogelstein B. Somatic mutations of the mitochondrial genome in human colorectal tumours. Nature Genetics. 20: 291-3. PMID 9806551 DOI: 10.1038/3108 |
0.392 |
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| 1998 |
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, Da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. Identification of c-MYC as a target of the APC pathway Science. 281: 1509-1512. PMID 9727977 DOI: 10.1126/Science.281.5382.1509 |
0.401 |
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| 1998 |
Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JPJ, Markowitz S, Willson JKV, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma Proceedings of the National Academy of Sciences of the United States of America. 95: 6870-6875. PMID 9618505 DOI: 10.1073/Pnas.95.12.6870 |
0.427 |
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| 1998 |
Kinzler KW, Vogelstein B. Landscaping the cancer terrain. Science (New York, N.Y.). 280: 1036-7. PMID 9616081 DOI: 10.1126/Science.280.5366.1036 |
0.389 |
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| 1998 |
Cahill DP, Lengauer C, Yu J, Riggins GJ, Willson JK, Markowitz SD, Kinzler KW, Vogelstein B. Mutations of mitotic checkpoint genes in human cancers. Nature. 392: 300-3. PMID 9521327 DOI: 10.1038/32688 |
0.414 |
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| 1998 |
Nicolaides NC, Littman SJ, Modrich P, Kinzler KW, Vogelstein B. A naturally occurring hPMS2 mutation can confer a dominant negative mutator phenotype Molecular and Cellular Biology. 18: 1635-1641. PMID 9488480 DOI: 10.1128/Mcb.18.3.1635 |
0.417 |
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| 1998 |
Zhou S, Buckhaults P, Zawel L, Bunz F, Riggins G, Dai JL, Kern SE, Kinzler KW, Vogelstein B. Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 2412-6. PMID 9482899 DOI: 10.1073/Pnas.95.5.2412 |
0.324 |
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| 1998 |
Chan TA, Morin PJ, Vogelstein B, Kinzler KW. Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis. Proceedings of the National Academy of Sciences of the United States of America. 95: 681-6. PMID 9435252 DOI: 10.1073/Pnas.95.2.681 |
0.349 |
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| 1997 |
Waldman T, Zhang Y, Dillehay L, Yu J, Kinzler K, Vogelstein B, Williams J. Cell-cycle arrest versus cell death in cancer therapy. Nature Medicine. 3: 1034-6. PMID 9288734 DOI: 10.1038/Nm0997-1034 |
0.378 |
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| 1997 |
Laken SJ, Petersen GM, Gruber SB, Oddoux C, Ostrer H, Giardiello FM, Hamilton SR, Hampel H, Markowitz A, Klimstra D, Jhanwar S, Winawer S, Offit K, Luce MC, Kinzler KW, et al. Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC Nature Genetics. 17: 79-83. PMID 9288102 DOI: 10.1038/Ng0997-79 |
0.392 |
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| 1997 |
Giardiello FM, Petersen GM, Piantadosi S, Gruber SB, Traboulsi EI, Offerhaus GJA, Muro K, Krush AJ, Booker SV, Luce MC, Laken SJ, Kinzler KW, Vogelstein B, Hamilton SR. APC gene mutations and extraintestinal phenotype of familial adenomatous polyposis Gut. 40: 521-525. PMID 9176082 DOI: 10.1136/Gut.40.4.521 |
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| 1997 |
Kinzler KW, Vogelstein B. Cancer-susceptibility genes. Gatekeepers and caretakers. Nature. 386: 761, 763. PMID 9126728 DOI: 10.1038/386761A0 |
0.377 |
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| 1997 |
Lengauer C, Kinzler KW, Vogelstein B. DNA methylation and genetic instability in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 2545-50. PMID 9122232 DOI: 10.1073/Pnas.94.6.2545 |
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| 1997 |
Lengauer C, Kinzler KW, Vogelstein B. Genetic instability in colorectal cancers. Nature. 386: 623-7. PMID 9121588 DOI: 10.1038/386623A0 |
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| 1997 |
Morin PJ, Sparks AB, Korinek V, Barker N, Clevers H, Vogelstein B, Kinzler KW. Activation of β-catenin-Tcf signaling in colon cancer by mutations in β-catenin or APC Science. 275: 1787-1790. PMID 9065402 DOI: 10.1126/Science.275.5307.1787 |
0.377 |
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| 1997 |
Korinek V, Barker N, Morin PJ, Van Wichen D, De Weger R, Kinzler KW, Vogelstein B, Clevers H. Constitutive transcriptional activation by a β-catenin-Tcf complex in APC(-/-) colon carcinoma Science. 275: 1784-1787. PMID 9065401 DOI: 10.1126/Science.275.5307.1784 |
0.303 |
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| 1997 |
Dunlop MG, Farrington SM, Carothers AD, Wyllie AH, Sharp L, Burn J, Liu B, Kinzler KW, Vogelstein B. Cancer risk associated with germline DNA mismatch repair gene mutations. Human Molecular Genetics. 6: 105-10. PMID 9002677 DOI: 10.1093/Hmg/6.1.105 |
0.389 |
|
| 1997 |
Nicolaides NC, Palombo F, Kinzler KW, Vogelstein B, Jiricny J. Molecular cloning of the N-terminus of GTBP. Genomics. 31: 395-7. PMID 8838326 DOI: 10.1006/Geno.1996.0067 |
0.396 |
|
| 1996 |
Huang J, Papadopoulos N, McKinley AJ, Farrington SM, Curtis LJ, Wyllie AH, Zheng S, Willson JK, Markowitz SD, Morin P, Kinzler KW, Vogelstein B, Dunlop MG. APC mutations in colorectal tumors with mismatch repair deficiency. Proceedings of the National Academy of Sciences of the United States of America. 93: 9049-54. PMID 8799152 DOI: 10.1073/Pnas.93.17.9049 |
0.427 |
|
| 1996 |
Beazer-Barclay Y, Levy DB, Moser AR, Dove WF, Hamilton SR, Vogelstein B, Kinzler KW. Sulindac suppresses tumorigenesis in the Min mouse. Carcinogenesis. 17: 1757-60. PMID 8761438 DOI: 10.1093/Carcin/17.8.1757 |
0.319 |
|
| 1996 |
Morin PJ, Vogelstein B, Kinzler KW. Apoptosis and APC in colorectal tumorigenesis Proceedings of the National Academy of Sciences of the United States of America. 93: 7950-7954. PMID 8755583 DOI: 10.1073/Pnas.93.15.7950 |
0.439 |
|
| 1996 |
Pietenpol JA, Lengauer C, Jordan J, Kinzler KW, Vogelstein B. Mammalian cells resistant to tumor suppressor genes Proceedings of the National Academy of Sciences of the United States of America. 93: 8390-8394. PMID 8710881 DOI: 10.1073/Pnas.93.16.8390 |
0.316 |
|
| 1996 |
Thiagalingam S, Lengauer C, Leach FS, Schutte M, Hahn SA, Overhauser J, Willson JK, Markowitz S, Hamilton SR, Kern SE, Kinzler KW, Vogelstein B. Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nature Genetics. 13: 343-6. PMID 8673134 DOI: 10.1038/Ng0796-343 |
0.371 |
|
| 1996 |
Nicolaides NC, Kinzler KW, Vogelstein B. Analysis of the 5' region of PMS2 reveals heterogeneous transcripts and a novel overlapping gene. Genomics. 29: 329-34. PMID 8666379 DOI: 10.1006/Geno.1995.9997 |
0.382 |
|
| 1996 |
Da Costa LT, Jen J, He TC, Chan TA, Kinzler KW, Vogelstein B. Converting cancer genes into killer genes. Proceedings of the National Academy of Sciences of the United States of America. 93: 4192-6. PMID 8633039 DOI: 10.1073/Pnas.93.9.4192 |
0.389 |
|
| 1996 |
Nicolaides NC, Carter KC, Shell BK, Papadopoulos N, Vogelstein B, Kinzler KW. Genomic organization of the human PMS2 gene family. Genomics. 30: 195-206. PMID 8586419 DOI: 10.1006/Geno.1995.9885 |
0.355 |
|
| 1996 |
Liu B, Parsons R, Papadopoulos N, Nicolaides NC, Lynch HT, Watson P, Jass JR, Dunlop M, Wyllie A, Peltomäki P, de la Chapelle A, Hamilton SR, Vogelstein B, Kinzler KW. Analysis of mismatch repair genes in hereditary non-polyposis colorectal cancer patients. Nature Medicine. 2: 169-74. PMID 8574961 DOI: 10.1038/Nm0296-169 |
0.437 |
|
| 1996 |
Kinzler KW, Vogelstein B. Life (and death) in a malignant tumour. Nature. 379: 19-20. PMID 8538735 DOI: 10.1038/379019A0 |
0.317 |
|
| 1995 |
Markowitz S, Wang J, Myeroff L, Parsons R, Sun L, Lutterbaugh J, Fan RS, Zborowska E, Kinzler KW, Vogelstein B. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science (New York, N.Y.). 268: 1336-8. PMID 7761852 DOI: 10.1126/Science.7761852 |
0.36 |
|
| 1995 |
Liu B, Nicolaides NC, Markowitz S, Willson JKV, Parsons RE, Jen J, Papadopolous N, Peltomäki P, de la Chapelle A, Hamilton SR, Kinzler KW, Vogelstein B. Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability Nature Genetics. 9: 48-55. PMID 7704024 DOI: 10.1038/Ng0195-48 |
0.416 |
|
| 1995 |
Hamilton SR, Parsons RE, Papadopoulos N, Jen J, Powell SM, Krush AJ, Berk T, Cohen Z, Tetu B, Burger PC, Wood PA, Taqi F, Booker SV, Petersen GM, Offerhaus GJA, ... ... Kinzler KW, et al. The molecular basis of Turcot's syndrome New England Journal of Medicine. 332: 839-847. PMID 7661930 DOI: 10.1056/Nejm199503303321302 |
0.395 |
|
| 1995 |
Parsons R, Li GM, Longley M, Modrich P, Liu B, Berk T, Hamilton SR, Kinzler KW, Vogelstein B. Mismatch repair deficiency in phenotypically normal human cells Science. 268: 738-740. PMID 7632227 DOI: 10.1126/Science.7632227 |
0.419 |
|
| 1995 |
Papadopoulos N, Nicolaides NC, Liu B, Parsons R, Lengauer C, Palombo F, D'Arrigo A, Markowitz S, Willson JK, Kinzler KW. Mutations of GTBP in genetically unstable cells. Science (New York, N.Y.). 268: 1915-7. PMID 7604266 DOI: 10.1126/Science.7604266 |
0.412 |
|
| 1995 |
Thiagalingam S, Kinzler KW, Vogelstein B. PAK1, a gene that can regulate p53 activity in yeast. Proceedings of the National Academy of Sciences of the United States of America. 92: 6062-6. PMID 7597081 DOI: 10.1073/Pnas.92.13.6062 |
0.342 |
|
| 1995 |
Vogelstein B, Kinzler KW. Colorectal cancer and the intersection between basic and clinical research. Cold Spring Harbor Symposia On Quantitative Biology. 59: 517-21. PMID 7587107 DOI: 10.1101/Sqb.1994.059.01.057 |
0.311 |
|
| 1995 |
Liu B, Farrington SM, Petersen GM, Hamilton SR, Parsons R, Papadopoulos N, Fujiwara T, Jen J, Kinzler KW, Wyllie AH, Vogelstein B, Dunlop MG. Genetic instability occurs in the majority of young patients with colorectal cancer. Nature Medicine. 1: 348-52. PMID 7585065 DOI: 10.1038/Nm0495-348 |
0.353 |
|
| 1994 |
Parsons R, Li GM, Longley MJ, Fang WH, Papadopoulos N, Jen J, de la Chapelle A, Kinzler KW, Vogelstein B, Modrich P. Hypermutability and mismatch repair deficiency in RER+ tumor cells. Cell. 75: 1227-36. PMID 8261516 DOI: 10.1016/0092-8674(93)90331-J |
0.429 |
|
| 1994 |
Su LK, Vogelstein B, Kinzler KW. Association of the APC tumor suppressor protein with catenins. Science (New York, N.Y.). 262: 1734-7. PMID 8259519 DOI: 10.1126/Science.8259519 |
0.414 |
|
| 1994 |
Kinzler KW, Vogelstein B. Cancer therapy meets p53. The New England Journal of Medicine. 331: 49-50. PMID 8202105 DOI: 10.1056/Nejm199407073310113 |
0.35 |
|
| 1994 |
Pietenpol JA, Tokino T, Thiagalingam S, El-Deiry WS, Kinzler KW, Vogelstein B. Sequence-specific transcriptional activation is essential for growth suppression by p53 Proceedings of the National Academy of Sciences of the United States of America. 91: 1998-2002. PMID 8134338 DOI: 10.1073/Pnas.91.6.1998 |
0.356 |
|
| 1994 |
Papadopoulos N, Nicolaides NC, Wei YF, Ruben SM, Carter KC, Rosen CA, Haseltine WA, Fleischmann RD, Fraser CM, Adams MD, Venter JC, Hamilton SR, Petersen GM, Watson P, Lynch HT, ... ... Kinzler KW, et al. Mutation of a mutL homolog in hereditary colon cancer Science. 263: 1625-1629. PMID 8128251 DOI: 10.1126/Science.8128251 |
0.421 |
|
| 1994 |
Jen J, Kim H, Piantadosi S, Liu ZF, Levitt RC, Sistonen P, Kinzler KW, Vogelstein B, Hamilton SR. Allelic loss of chromosome 18q and prognosis in colorectal cancer. The New England Journal of Medicine. 331: 213-21. PMID 8015568 DOI: 10.1056/Nejm199407283310401 |
0.354 |
|
| 1994 |
Powell SM, Papadopoulos N, Kinzler KW, Smolinski KN, Meltzer SJ. APC gene mutations in the mutation cluster region are rare in esophageal cancers. Gastroenterology. 107: 1759-63. PMID 7958689 DOI: 10.1016/0016-5085(94)90818-4 |
0.429 |
|
| 1994 |
Hedrick L, Cho KR, Fearon ER, Wu TC, Kinzler KW, Vogelstein B. The DCC gene product in cellular differentiation and colorectal tumorigenesis. Genes & Development. 8: 1174-83. PMID 7926722 DOI: 10.1101/Gad.8.10.1174 |
0.409 |
|
| 1994 |
Vogelstein B, Kinzler KW. Has the breast cancer gene been found? Cell. 79: 1-3. PMID 7923368 DOI: 10.1016/0092-8674(94)90393-X |
0.318 |
|
| 1993 |
Vogelstein B, Kinzler KW. The multistep nature of cancer. Trends in Genetics : Tig. 9: 138-41. PMID 8516849 DOI: 10.1016/0168-9525(93)90209-Z |
0.416 |
|
| 1993 |
Kinzler KW, Vogelstein B. Cancer. A gene for neurofibromatosis 2. Nature. 363: 495-6. PMID 8505975 DOI: 10.1038/363495A0 |
0.382 |
|
| 1993 |
Petersen GM, Francomano C, Kinzler K, Nakamura Y. Presymptomatic direct detection of adenomatous polyposis coli (APC) gene mutations in familial adenomatous polyposis Human Genetics. 91: 307-311. PMID 8388848 DOI: 10.1007/Bf00217347 |
0.336 |
|
| 1993 |
Luongo C, Gould KA, Su LK, Kinzler KW, Vogelstein B, Dietrich W, Lander ES, Moser AR. Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse. Genomics. 15: 3-8. PMID 8094372 DOI: 10.1006/Geno.1993.1002 |
0.368 |
|
| 1993 |
Simons JW, Oliner JD, Cho KR, Kinzler KW, Vogelstein B. SAM 1.1 and JOSH 4.4: two RFLPs within the human DCC gene. Human Molecular Genetics. 1: 352. PMID 1363875 DOI: 10.1093/Hmg/1.5.352 |
0.305 |
|
| 1993 |
Nakamura Y, Nishisho I, Kinzler KW, Vogelstein B, Miyoshi Y, Miki Y, Ando H, Horii A. Mutations of the APC (adenomatous polyposis coli) gene in FAP (familial polyposis coli) patients and in sporadic colorectal tumors. The Tohoku Journal of Experimental Medicine. 168: 141-7. PMID 1339098 DOI: 10.1620/Tjem.168.141 |
0.339 |
|
| 1992 |
Oliner JD, Kinzler KW, Meltzer PS, George DL, Vogelstein B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature. 358: 80-3. PMID 1614537 DOI: 10.1038/358080A0 |
0.366 |
|
| 1992 |
Kern SE, Pietenpol JA, Thiagalingam S, Seymour A, Kinzler KW, Vogelstein B. Oncogenic forms of p53 inhibit p53-regulated gene expression Science. 256: 827-830. PMID 1589764 DOI: 10.1126/Science.1589764 |
0.344 |
|
| 1992 |
Sidransky D, Tokino T, Hamilton SR, Kinzler KW, Levin B, Frost P, Vogelstein B. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science (New York, N.Y.). 256: 102-5. PMID 1566048 DOI: 10.1126/Science.1566048 |
0.408 |
|
| 1992 |
Powell SM, Zilz N, Beazer-Barclay Y, Bryan TM, Hamilton SR, Thibodeau SN, Vogelstein B, Kinzler KW. APC mutations occur early during colorectal tumorigenesis. Nature. 359: 235-7. PMID 1528264 DOI: 10.1038/359235A0 |
0.399 |
|
| 1992 |
Su LK, Kinzler KW, Vogelstein B, Preisinger AC, Moser AR, Luongo C, Gould KA, Dove WF. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science (New York, N.Y.). 256: 668-70. PMID 1350108 DOI: 10.1126/Science.1350108 |
0.435 |
|
| 1992 |
Miyoshi Y, Nishisho I, Miki Y, Mori T, Kinzler KW, Vogelstein B, Nakamura Y. Insertion/deletion polymorphism and other restriction fragment length polymorphisms in the MCC gene. Japanese Journal of Cancer Research : Gann. 83: 10-4. PMID 1347524 DOI: 10.1111/J.1349-7006.1992.Tb02344.X |
0.352 |
|
| 1992 |
Kinzler KW, Vogelstein B. The colorectal cancer gene hunt: current findings. Hospital Practice (Office Ed.). 27: 51-8. PMID 1331139 DOI: 10.1080/21548331.1992.11705522 |
0.419 |
|
| 1992 |
Su L, Kinzler KW, Vogelstein B, Preisinger AC, Moser AR, Luongo C, Gould KA, Dove WF. Corrections and Clarifications: Multiple Intestinal Neoplasia Caused By a Mutation in the Murine Homolog of the APC Gene Science. 256: 1114-1114. DOI: 10.1126/Science.256.5060.1114-C |
0.362 |
|
| 1991 |
Kinzler KW, Nilbert MC, Vogelstein B, Bryan TM, Levy DB, Smith KJ, Preisinger AC, Hamilton SR, Hedge P, Markham A. Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science (New York, N.Y.). 251: 1366-70. PMID 1848370 DOI: 10.1126/Science.1848370 |
0.455 |
|
| 1991 |
Ruppert JM, Vogelstein B, Kinzler KW. The zinc finger protein GLI transforms primary cells in cooperation with adenovirus E1A. Molecular and Cellular Biology. 11: 1724-8. PMID 1825351 DOI: 10.1128/Mcb.11.3.1724 |
0.303 |
|
| 1991 |
Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S, Hedge P, Markham A, Krush AJ, Petersen G, Hamilton SR, Nilbert MC, ... ... Kinzler KW, et al. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients Science. 253: 665-669. PMID 1651563 DOI: 10.1126/Science.1651563 |
0.428 |
|
| 1990 |
Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, Ruppert JM, Hamilton SR, Preisinger AC, Thomas G, Kinzler KW. Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (New York, N.Y.). 247: 49-56. PMID 2294591 DOI: 10.1126/Science.2294591 |
0.422 |
|
| 1990 |
Ruppert JM, Vogelstein B, Arheden K, Kinzler KW. GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity. Molecular and Cellular Biology. 10: 5408-15. PMID 2118997 DOI: 10.1128/Mcb.10.10.5408 |
0.326 |
|
| 1990 |
Kinzler KW, Vogelstein B. The GLI gene encodes a nuclear protein which binds specific sequences in the human genome. Molecular and Cellular Biology. 10: 634-42. PMID 2105456 DOI: 10.1128/Mcb.10.2.634 |
0.317 |
|
| 1987 |
Kinzler KW, Bigner SH, Bigner DD, Trent JM, Law ML, O'Brien SJ, Wong AJ, Vogelstein B. Identification of an amplified, highly expressed gene in a human glioma. Science (New York, N.Y.). 236: 70-3. PMID 3563490 DOI: 10.1126/Science.3563490 |
0.38 |
|
| 1987 |
Wong AJ, Bigner SH, Bigner DD, Kinzler KW, Hamilton SR, Vogelstein B. Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification. Proceedings of the National Academy of Sciences of the United States of America. 84: 6899-903. PMID 3477813 DOI: 10.1073/Pnas.84.19.6899 |
0.374 |
|
| 1987 |
Bigner S, Wong A, Mark J, Kinzler K, Vogelstein B, Bigner D. 13 Chromosomes and gene amplification in malignant human gliomas (MHG) Cancer Genetics and Cytogenetics. 28: 32. DOI: 10.1016/0165-4608(87)90292-5 |
0.304 |
|
| 1986 |
Kinzler KW, Zehnbauer BA, Brodeur GM, Seeger RC, Trent JM, Meltzer PS, Vogelstein B. Amplification units containing human N-myc and c-myc genes Proceedings of the National Academy of Sciences of the United States of America. 83: 1031-1035. PMID 3006024 DOI: 10.1073/Pnas.83.4.1031 |
0.343 |
|
| 1986 |
Trent J, Meltzer P, Rosenblum M, Harsh G, Kinzler K, Mashal R, Feinberg A, Vogelstein B. Evidence for rearrangement, amplification, and expression of c-myc in a human glioblastoma Proceedings of the National Academy of Sciences of the United States of America. 83: 470-473. PMID 3001737 DOI: 10.1073/Pnas.83.2.470 |
0.388 |
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