| Year |
Citation |
Score |
| 2023 |
Liao G, Wang R, Wu Y, Maheshwari NK, Penn RB, Tang DD. Nestin drives allergen-induced airway smooth muscle hyperplasia and airway remodeling. Allergy. PMID 37897062 DOI: 10.1111/all.15932 |
0.364 |
|
| 2023 |
Tompkins E, Mimic B, Penn RB, Pera T. The biased M3 mAChR ligand PD 102807 mediates qualitatively distinct signaling to regulate airway smooth muscle phenotype. The Journal of Biological Chemistry. 299: 105209. PMID 37660916 DOI: 10.1016/j.jbc.2023.105209 |
0.345 |
|
| 2023 |
Nayak AP, Javed E, Villalba DR, Wang Y, Morelli HP, Shah SD, Kim N, Ostrom RS, Panettieri RA, An SS, Tang DD, Penn RB. Pro-Relaxant EP Receptors Functionally Partition to Different Pro-Contractile Receptors in Airway Smooth Muscle. American Journal of Respiratory Cell and Molecular Biology. PMID 37523713 DOI: 10.1165/rcmb.2022-0445OC |
0.396 |
|
| 2023 |
Ippolito M, De Pascali F, Hopfinger N, Komolov KE, Laurinavichyute D, Reddy PAN, Sakkal LA, Rajkowski KZ, Nayak AP, Lee J, Lee J, Cao G, Donover PS, Reichman M, An SS, ... ... Penn RB, et al. Identification of a β-arrestin-biased negative allosteric modulator for the β-adrenergic receptor. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302668120. PMID 37490535 DOI: 10.1073/pnas.2302668120 |
0.359 |
|
| 2023 |
Hernandez-Lara MA, Yadav SK, Conaway S, Shah SD, Penn RB, Deshpande DA. Crosstalk between diacylglycerol kinase and protein kinase A in the regulation of airway smooth muscle cell proliferation. Respiratory Research. 24: 155. PMID 37301818 DOI: 10.1186/s12931-023-02465-8 |
0.442 |
|
| 2022 |
Shah SD, Lind C, De Pascali F, Penn RB, MacKerell AD, Deshpande DA. In silico identification of a β-adrenoceptor allosteric site that selectively augments canonical βAR-Gs signaling and function. Proceedings of the National Academy of Sciences of the United States of America. 119: e2214024119. PMID 36449547 DOI: 10.1073/pnas.2214024119 |
0.358 |
|
| 2022 |
Hernandez-Lara MA, Yadav SK, Shah SD, Okumura M, Yokoyama Y, Penn RB, Kambayashi T, Deshpande DA. Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma. International Journal of Molecular Sciences. 23. PMID 36233170 DOI: 10.3390/ijms231911868 |
0.462 |
|
| 2022 |
Deshpande DA, Penn RB. A cryptic mode of GPCR regulation revealed. Trends in Molecular Medicine. PMID 36109317 DOI: 10.1016/j.molmed.2022.08.011 |
0.351 |
|
| 2022 |
Tompkins E, Mimic B, Cuevas-Mora K, Schorsch H, Shah SD, Deshpande DA, Benovic JL, Penn RB, Pera T. PD 102807 Induces M3 mAChR-dependent GRK-/arrestin-biased Signaling in Airway Smooth Muscle Cells. American Journal of Respiratory Cell and Molecular Biology. PMID 35944139 DOI: 10.1165/rcmb.2021-0320OC |
0.311 |
|
| 2022 |
Wang R, Wang Y, Liao G, Chen B, Panettieri RA, Penn RB, Tang DD. Abi1 mediates airway smooth muscle cell proliferation and airway remodeling via Jak2/STAT3 signaling. Iscience. 25: 103833. PMID 35198891 DOI: 10.1016/j.isci.2022.103833 |
0.397 |
|
| 2021 |
Nayak AP, Deshpande DA, Shah SD, Villalba DR, Yi R, Wang N, Penn RB. OGR1-dependent regulation of the allergen-induced asthma phenotype. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 34668419 DOI: 10.1152/ajplung.00200.2021 |
0.349 |
|
| 2021 |
Sharma P, Yadav SK, Shah SD, Javed E, Lim JM, Pan S, Nayak AP, Panettieri RA, Penn RB, Kambayashi T, Deshpande DA. Diacylglycerol Kinase Inhibition Reduces Airway Contraction by Negative Feedback Regulation of Gq-signaling. American Journal of Respiratory Cell and Molecular Biology. PMID 34293268 DOI: 10.1165/rcmb.2021-0106OC |
0.444 |
|
| 2021 |
Yadav SK, Sharma P, Shah SD, Panettieri RA, Kambayashi T, Penn RB, Deshpande DA. Autocrine regulation of airway smooth muscle contraction by diacylglycerol kinase. Journal of Cellular Physiology. PMID 34278583 DOI: 10.1002/jcp.30528 |
0.457 |
|
| 2021 |
Nayak AP, Lim JM, Arbel E, Wang R, Villalba DR, Nguyen TL, Schaible N, Krishnan R, Tang DD, Penn RB. Cooperativity between β-agonists and c-Abl inhibitors in regulating airway smooth muscle relaxation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21674. PMID 34115899 DOI: 10.1096/fj.202100154R |
0.4 |
|
| 2021 |
Sharma P, Penn RB. Can GPCRs Be Targeted to Control Inflammation in Asthma? Advances in Experimental Medicine and Biology. 1304: 1-20. PMID 34019260 DOI: 10.1007/978-3-030-68748-9_1 |
0.437 |
|
| 2020 |
Krymskaya VP, Penn RB. Enlightening Ways to Relax Airway Smooth Muscle: Opsins. American Journal of Respiratory Cell and Molecular Biology. PMID 33166477 DOI: 10.1165/rcmb.2020-0468ED |
0.329 |
|
| 2020 |
Huang J, Lam H, Koziol-White C, Limjunyawong N, Kim D, Kim N, Karmacharya N, Rajkumar P, Firer D, Dalesio NM, Jude J, Kurten RC, Pluznick JL, Deshpande DA, Penn RB, et al. The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. Proceedings of the National Academy of Sciences of the United States of America. PMID 33097666 DOI: 10.1073/pnas.2003111117 |
0.331 |
|
| 2020 |
Penn RB. Mast cells in asthma: Here I am, stuck in the middle with you. The European Respiratory Journal. 56. PMID 32616549 DOI: 10.1183/13993003.01337-2020 |
0.413 |
|
| 2020 |
Nayak AP, Penn RB. The proton-sensing receptor ovarian cancer G-protein coupled receptor 1 (OGR1) in airway physiology and disease. Current Opinion in Pharmacology. 51: 1-10. PMID 32361614 DOI: 10.1016/J.Coph.2020.03.004 |
0.462 |
|
| 2020 |
Chan TO, Armen RS, Yadav S, Shah S, Zhang J, Tiegs BC, Keny N, Blumhof B, Deshpande DA, Rodeck U, Penn RB. A tripartite cooperative mechanism confers resistance of the protein kinase A catalytic subunit to dephosphorylation. The Journal of Biological Chemistry. PMID 31964716 DOI: 10.1074/Jbc.Ra119.010004 |
0.406 |
|
| 2019 |
Javed E, Thangavel C, Frara N, Singh J, Mohanty I, Hypolite J, Birbe R, Braverman AS, Den RB, Rattan S, Zderic SA, Deshpande DA, Penn RB, Ruggieri MR, Chacko S, et al. Increased expression of desmin and vimentin reduces bladder smooth muscle contractility via JNK2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31909533 DOI: 10.1096/Fj.201901301R |
0.472 |
|
| 2019 |
Nunez FJ, Schulte NA, Fogel DM, Michalski J, Rennard SI, Penn RB, Toews ML, Ostrom RS. Agonist-specific desensitization of PGE-stimulated cAMP signaling due to upregulated phosphodiesterase expression in human lung fibroblasts. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 31884570 DOI: 10.1007/S00210-019-01800-5 |
0.476 |
|
| 2019 |
Foster SR, Hauser AS, Vedel L, Strachan RT, Huang XP, Gavin AC, Shah SD, Nayak AP, Haugaard-Kedström LM, Penn RB, Roth BL, Bräuner-Osborne H, Gloriam DE. Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors. Cell. 179: 895-908.e21. PMID 31675498 DOI: 10.1016/J.Cell.2019.10.010 |
0.351 |
|
| 2019 |
Pera T, Tompkins E, Katz M, Wang B, Deshpande DA, Weinman EJ, Penn RB. Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900323R. PMID 31042404 DOI: 10.1096/Fj.201900323R |
0.508 |
|
| 2019 |
Pera T, Penn RB. Methods to Investigate β-Arrestin-Mediated Regulation of GPCR Function in Human Airway Smooth Muscle. Methods in Molecular Biology (Clifton, N.J.). 1957: 69-82. PMID 30919347 DOI: 10.1007/978-1-4939-9158-7_4 |
0.489 |
|
| 2019 |
Nayak AP, Pera T, Deshpande DA, Michael JV, Liberato JR, Pan S, Tompkins E, Morelli HP, Yi R, Wang N, Penn RB. Regulation of Ovarian cancer G protein-coupled receptor (OGR1) expression and signaling. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 30724097 DOI: 10.1152/Ajplung.00426.2018 |
0.465 |
|
| 2019 |
Thangavel C, Gomes CM, Zderic SA, Javed E, Addya S, Singh J, Das S, Birbe R, Den RB, Rattan S, Deshpande DA, Penn RB, Chacko S, Boopathi E. NF-κB and GATA-6 Repress Transcription of Caveolins in Bladder Smooth Muscle Hypertrophy. The American Journal of Pathology. PMID 30707892 DOI: 10.1016/J.Ajpath.2018.12.013 |
0.392 |
|
| 2019 |
Michael JV, Gavrila A, Nayak AP, Pera T, Liberato JR, Polischak SR, Shah SD, Deshpande DA, Penn RB. Cooperativity of E-prostanoid receptor subtypes in regulating signaling and growth inhibition in human airway smooth muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201801959R. PMID 30601680 DOI: 10.1096/Fj.201801959R |
0.519 |
|
| 2018 |
Yadav SK, Shah SD, Penn RB. Give Me a Fork: Can Autophagy Research Solve the Riddle of Airway Remodeling in Asthma? American Journal of Respiratory Cell and Molecular Biology. PMID 30423254 DOI: 10.1165/Rcmb.2018-0353Ed |
0.331 |
|
| 2018 |
Nayak AP, Deshpande DA, Penn RB. New targets for resolution of airway remodeling in obstructive lung diseases. F1000research. 7. PMID 29904584 DOI: 10.12688/F1000Research.14581.1 |
0.352 |
|
| 2018 |
Panettieri RA, Pera T, Liggett SB, Benovic JL, Penn RB. Pepducins as a potential treatment strategy for asthma and COPD. Current Opinion in Pharmacology. 40: 120-125. PMID 29729548 DOI: 10.1016/J.Coph.2018.04.008 |
0.481 |
|
| 2017 |
Pera T, Deshpande DA, Ippolito M, Wang B, Gavrila A, Michael JV, Nayak AP, Tompkins E, Farrell E, Kroeze WK, Roth BL, Panettieri RA, Benovic JL, An SS, Dulin NO, ... Penn RB, et al. Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29042451 DOI: 10.1096/Fj.201700555R |
0.424 |
|
| 2017 |
Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA. Gα12 Facilitates Carbachol-Induced Shortening in Human Airway Smooth Muscle By Modulating Phosphoinositide 3-Kinase-Mediated Activation In A RhoA-Dependent Manner. British Journal of Pharmacology. PMID 28921504 DOI: 10.1111/Bph.14040 |
0.562 |
|
| 2016 |
Billington CK, Penn RB, Hall IP. β2 Agonists. Handbook of Experimental Pharmacology. PMID 27878470 DOI: 10.1007/164_2016_64 |
0.421 |
|
| 2016 |
Pera T, Penn RB. Bronchoprotection and bronchorelaxation in asthma: New targets, and new ways to target the old ones. Pharmacology & Therapeutics. PMID 27113408 DOI: 10.1016/J.Pharmthera.2016.04.002 |
0.445 |
|
| 2016 |
Forkuo GS, Kim H, Thanawala VJ, Al-Sawalha N, Valdez D, Joshi R, Parra S, Pera T, Gonnella PA, Knoll BJ, Walker JK, Penn RB, Bond RA. PDE4 Inhibitors Attenuate the Asthma Phenotype Produced by β2-adrenoceptor Agonists in PNMT-KO Mice. American Journal of Respiratory Cell and Molecular Biology. PMID 26909542 DOI: 10.1165/Rcmb.2015-0373Oc |
0.429 |
|
| 2015 |
Huang XP, Karpiak J, Kroeze WK, Zhu H, Chen X, Moy SS, Saddoris KA, Nikolova VD, Farrell MS, Wang S, Mangano TJ, Deshpande DA, Jiang A, Penn RB, Jin J, et al. Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65. Nature. PMID 26550826 DOI: 10.1038/Nature15699 |
0.341 |
|
| 2015 |
Chan TO, Zhang J, Tiegs BC, Blumhof B, Yan L, Keny N, Penny M, Li X, Pascal JM, Armen RS, Rodeck U, Penn RB. Akt Kinase C-Terminal Modifications Control Activation Loop Dephosphorylation and Enhance Insulin Response. The Biochemical Journal. PMID 26201515 DOI: 10.1042/Bj20150325 |
0.379 |
|
| 2015 |
Pera T, Hegde A, Deshpande DA, Morgan SJ, Tiegs BC, Theriot BS, Choi YH, Walker JK, Penn RB. Specificity of arrestin subtypes in regulating airway smooth muscle G protein-coupled receptor signaling and function. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26103985 DOI: 10.1096/Fj.15-273094 |
0.516 |
|
| 2015 |
Penn RB. Physiology. Calcilytics for asthma relief. Science (New York, N.Y.). 348: 398-9. PMID 25908810 DOI: 10.1126/Science.Aab2173 |
0.482 |
|
| 2014 |
Morgan SJ, Deshpande DA, Tiegs BC, Misior AM, Yan H, Hershfeld AV, Rich TC, Panettieri RA, An SS, Penn RB. β-Agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent. The Journal of Biological Chemistry. 289: 23065-74. PMID 24973219 DOI: 10.1074/Jbc.M114.557652 |
0.795 |
|
| 2014 |
Pera T, Penn RB. Crosstalk between beta-2-adrenoceptor and muscarinic acetylcholine receptors in the airway. Current Opinion in Pharmacology. 16: 72-81. PMID 24747364 DOI: 10.1016/J.Coph.2014.03.005 |
0.492 |
|
| 2014 |
Penn RB, Bond RA, Walker JK. GPCRs and arrestins in airways: implications for asthma. Handbook of Experimental Pharmacology. 219: 387-403. PMID 24292841 DOI: 10.1007/978-3-642-41199-1_20 |
0.491 |
|
| 2014 |
Deshpande DA, Yan H, Kong KC, Tiegs BC, Morgan SJ, Pera T, Panettieri RA, Eckhart AD, Penn RB. Exploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscle Faseb Journal. 28: 956-965. PMID 24132623 DOI: 10.1096/Fj.13-240226 |
0.496 |
|
| 2014 |
Morgan SJ, Deshpande DA, Tiegs BC, Misior AM, Yan H, Hershfeld AV, Rich TC, Panettieri RA, An SS, Penn RB. β-agonist-mediated relaxation of airway smooth muscle is protein kinase A-dependent Journal of Biological Chemistry. 289: 23065-23074. DOI: 10.1074/jbc.M114.557652 |
0.794 |
|
| 2014 |
Pera T, Penn RB. Crosstalk between beta-2-adrenoceptor and muscarinic acetylcholine receptors in the airway Current Opinion in Pharmacology. 16: 72-81. DOI: 10.1016/j.coph.2014.03.005 |
0.33 |
|
| 2013 |
Billington CK, Ojo OO, Penn RB, Ito S. cAMP regulation of airway smooth muscle function Pulmonary Pharmacology and Therapeutics. 26: 112-120. PMID 22634112 DOI: 10.1016/J.Pupt.2012.05.007 |
0.526 |
|
| 2012 |
Horvat SJ, Deshpande DA, Yan H, Panettieri RA, Codina J, DuBose TD, Xin W, Rich TC, Penn RB. A-kinase anchoring proteins regulate compartmentalized cAMP signaling in airway smooth muscle Faseb Journal. 26: 3670-3679. PMID 22649031 DOI: 10.1096/Fj.11-201020 |
0.492 |
|
| 2012 |
Goncharova EA, Goncharov DA, Zhao H, Penn RB, Krymskaya VP, Panettieri RA. β 2-adrenergic receptor agonists modulate human airway smooth muscle cell migration via vasodilator-stimulated phosphoprotein American Journal of Respiratory Cell and Molecular Biology. 46: 48-54. PMID 22210825 DOI: 10.1165/Rcmb.2011-0217Oc |
0.57 |
|
| 2012 |
Saxena H, Deshpande DA, Tiegs BC, Yan H, Battafarano RJ, Burrows WM, Damera G, Panettieri RA, Dubose TD, An SS, Penn RB. The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH British Journal of Pharmacology. 166: 981-990. PMID 22145625 DOI: 10.1111/J.1476-5381.2011.01807.X |
0.419 |
|
| 2011 |
Codina J, Opyd TS, Powell ZB, Furdui CM, Petrovic S, Penn RB, Dubose TD. pH-dependent regulation of the α-subunit of H +-K +-ATPase (HK α2) American Journal of Physiology - Renal Physiology. 301: F536-F543. PMID 21653633 DOI: 10.1152/Ajprenal.00220.2011 |
0.356 |
|
| 2011 |
Walker JKL, Penn RB, Hanania NA, Dickey BF, Bond RA. New perspectives regarding β 2-adrenoceptor ligands in the treatment of asthma British Journal of Pharmacology. 163: 18-28. PMID 21175591 DOI: 10.1111/J.1476-5381.2010.01178.X |
0.42 |
|
| 2011 |
Yan H, Deshpande DA, Misior AM, Miles MC, Saxena H, Riemer EC, Pascual RM, Panettieri RA, Penn RB. Anti-mitogenic effects of β-agonists and PGE2on airway smooth muscle are PKA dependent Faseb Journal. 25: 389-397. PMID 20805374 DOI: 10.1096/Fj.10-164798 |
0.799 |
|
| 2010 |
Sun X, Yang LV, Tiegs BC, Arend LJ, McGraw DW, Penn RB, Petrovic S. Deletion of the pH sensor GPR4 decreases renal acid excretion Journal of the American Society of Nephrology. 21: 1745-1755. PMID 20798260 DOI: 10.1681/Asn.2009050477 |
0.301 |
|
| 2010 |
Loza MJ, Foster S, Bleecker ER, Peters SP, Penn RB. Asthma and gender impact accumulation of T cell subtypes. Respiratory Research. 11: 103. PMID 20667106 DOI: 10.1186/1465-9921-11-103 |
0.338 |
|
| 2010 |
Loza MJ, Penn RB. Regulation of T cells in airway disease by beta-agonist Frontiers in Bioscience - Scholar. 2: 969-979. PMID 20515836 DOI: 10.2741/S113 |
0.444 |
|
| 2009 |
Penn RB. Agonizing over agonism: Should asthmatics turn their β-receptors on or off? Proceedings of the National Academy of Sciences of the United States of America. 106: 2095-2096. PMID 19211783 DOI: 10.1073/Pnas.0812935106 |
0.481 |
|
| 2009 |
Misior AM, Deshpande DA, Loza MJ, Pascual RM, Hipp JD, Penn RB. Glucocorticoid- and protein kinase A-dependent transcriptome regulation in airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 41: 24-39. PMID 19059887 DOI: 10.1165/Rcmb.2008-0266Oc |
0.802 |
|
| 2008 |
Kong KC, Gandhi U, Martin TJ, Anz CB, Yan H, Misior AM, Pascual RM, Deshpande DA, Penn RB. Endogenous Gs-coupled receptors in smooth muscle exhibit differential susceptibility to GRK2/3-mediated desensitization. Biochemistry. 47: 9279-88. PMID 18690720 DOI: 10.1021/Bi801056W |
0.786 |
|
| 2008 |
Hua X, Chason KD, Fredholm BB, Deshpande DA, Penn RB, Tilley SL. Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells. The Journal of Allergy and Clinical Immunology. 122: 107-13, 113.e1-7. PMID 18472152 DOI: 10.1016/J.Jaci.2008.03.026 |
0.405 |
|
| 2008 |
Deshpande DA, Theriot BS, Penn RB, Walker JK. Beta-arrestins specifically constrain beta2-adrenergic receptor signaling and function in airway smooth muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2134-41. PMID 18337459 DOI: 10.1096/Fj.07-102459 |
0.555 |
|
| 2008 |
Penn RB. Embracing emerging paradigms of G protein-coupled receptor agonism and signaling to address airway smooth muscle pathobiology in asthma Naunyn-Schmiedeberg's Archives of Pharmacology. 378: 149-169. PMID 18278482 DOI: 10.1007/S00210-008-0263-1 |
0.491 |
|
| 2008 |
Loza MJ, Foster S, Peters SP, Penn RB. Interactive effects of steroids and β-agonists on accumulation of type 2 T cells Journal of Allergy and Clinical Immunology. 121: 750.e1-755.e3. PMID 18155275 DOI: 10.1016/J.Jaci.2007.10.036 |
0.47 |
|
| 2008 |
Penn RB, Benovic JL. Regulation of heterotrimeric G protein signaling in airway smooth muscle. Proceedings of the American Thoracic Society. 5: 47-57. PMID 18094084 DOI: 10.1513/pats.200705-054VS |
0.332 |
|
| 2008 |
Komalavilas P, Penn RB, Flynn CR, Thresher J, Lopes LB, Furnish EJ, Guo M, Pallero MA, Murphy-Ullrich JE, Brophy CM. The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L69-78. PMID 17993590 DOI: 10.1152/Ajplung.00235.2007 |
0.445 |
|
| 2008 |
Misior AM, Yan H, Pascual RM, Deshpande DA, Panettieri RA, Penn RB. Mitogenic effects of cytokines on smooth muscle are critically dependent on protein kinase A and are unmasked by steroids and cyclooxygenase inhibitors. Molecular Pharmacology. 73: 566-74. PMID 17993511 DOI: 10.1124/Mol.107.040519 |
0.794 |
|
| 2008 |
MISIOR A, YAN H, PASCUAL R, DESHPANDE D, PENN R. Protein Kinase A (PKA) Inhibition Renders Interleukin-1 Beta (IL-1β) Pro-mitogenic to Human Airway Smooth Muscle (ASM) Cells: Role of Induced GPCR Ligands Journal of Allergy and Clinical Immunology. 121: S48-S48. DOI: 10.1016/J.Jaci.2007.12.193 |
0.796 |
|
| 2007 |
Hua X, Erikson CJ, Chason KD, Rosebrock CN, Deshpande DA, Penn RB, Tilley SL. Involvement of A1 adenosine receptors and neural pathways in adenosine-induced bronchoconstriction in mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L25-32. PMID 17468137 DOI: 10.1152/Ajplung.00058.2007 |
0.398 |
|
| 2007 |
Deshpande DA, Pascual RM, Wang SW, Eckman DM, Riemer EC, Funk CD, Penn RB. PKC-dependent regulation of the receptor locus dominates functional consequences of cysteinyl leukotriene type 1 receptor activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2335-42. PMID 17392478 DOI: 10.1096/Fj.06-8060Com |
0.584 |
|
| 2007 |
Sastry KS, Karpova Y, Prokopovich S, Smith AJ, Essau B, Gersappe A, Carson JP, Weber MJ, Register TC, Chen YQ, Penn RB, Kulik G. Epinephrine protects cancer cells from apoptosis via activation of cAMP-dependent protein kinase and BAD phosphorylation. The Journal of Biological Chemistry. 282: 14094-100. PMID 17353197 DOI: 10.1074/Jbc.M611370200 |
0.407 |
|
| 2007 |
Loza MJ, Peters SP, Foster S, Khan IU, Penn RB. β-Agonist enhances type 2 T-cell survival and accumulation Journal of Allergy and Clinical Immunology. 119: 235-244. PMID 17208607 DOI: 10.1016/J.Jaci.2006.09.019 |
0.432 |
|
| 2006 |
Deshpande DA, Penn RB. Targeting G protein-coupled receptor signaling in asthma. Cellular Signalling. 18: 2105-20. PMID 16828259 DOI: 10.1016/J.Cellsig.2006.04.008 |
0.479 |
|
| 2006 |
Codina J, Liu J, Bleyer AJ, Penn RB, DuBose TD. Phosphorylation of S955 at the protein kinase A consensus promotes maturation of the alpha subunit of the colonic H+,K+ -ATPase. Journal of the American Society of Nephrology : Jasn. 17: 1833-40. PMID 16738016 DOI: 10.1681/Asn.2006010032 |
0.303 |
|
| 2006 |
Kong KC, Billington CK, Gandhi U, Panettieri RA, Penn RB. Cooperative mitogenic signaling by G protein-coupled receptors and growth factors is dependent on G(q/11). Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1558-60. PMID 16723377 DOI: 10.1096/Fj.05-5622Fje |
0.452 |
|
| 2006 |
Pascual RM, Carr EM, Seeds MC, Guo M, Panettieri RA, Peters SP, Penn RB. Regulatory features of interleukin-1beta-mediated prostaglandin E2 synthesis in airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L501-8. PMID 16299051 DOI: 10.1152/Ajplung.00420.2005 |
0.463 |
|
| 2006 |
Loza MJ, Foster S, Peters SP, Penn RB. Beta-agonists modulate T-cell functions via direct actions on type 1 and type 2 cells. Blood. 107: 2052-60. PMID 16278302 DOI: 10.1182/Blood-2005-08-3265 |
0.443 |
|
| 2006 |
Allen IC, Hartney JM, Coffman TM, Penn RB, Wess J, Koller BH. Thromboxane A2 induces airway constriction through an M3 muscarinic acetylcholine receptor-dependent mechanism. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L526-33. PMID 16243899 DOI: 10.1152/Ajplung.00340.2005 |
0.518 |
|
| 2005 |
Billington CK, Kong KC, Bhattacharyya R, Wedegaertner PB, Panettieri RA, Chan TO, Penn RB. Cooperative regulation of p70S6 kinase by receptor tyrosine kinases and G protein-coupled receptors augments airway smooth muscle growth. Biochemistry. 44: 14595-605. PMID 16262259 DOI: 10.1021/Bi0510734 |
0.497 |
|
| 2005 |
Guo M, Pascual RM, Wang S, Fontana MF, Valancius CA, Panettieri RA, Tilley SL, Penn RB. Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms. Biochemistry. 44: 13771-82. PMID 16229467 DOI: 10.1021/Bi051255Y |
0.591 |
|
| 2005 |
Huang CD, Ammit AJ, Tliba O, Kuo HP, Penn RB, Panettieri RA, Amrani Y. G-protein-coupled receptor agonists differentially regulate basal or tumor necrosis factor-alpha-stimulated activation of interleukin-6 and RANTES in human airway smooth muscle cells. Journal of Biomedical Science. 12: 763-76. PMID 16228299 DOI: 10.1007/S11373-005-9008-Z |
0.439 |
|
| 2005 |
Loza MJ, Peters SP, Penn RB. Atopy, asthma, and experimental approaches based on the linear model of T cell maturation. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 35: 8-17. PMID 15649260 DOI: 10.1111/J.1365-2222.2004.02148.X |
0.309 |
|
| 2005 |
Naik S, Billington CK, Pascual RM, Deshpande DA, Stefano FP, Kohout TA, Eckman DM, Benovic JL, Penn RB. Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling. The Journal of Biological Chemistry. 280: 8722-32. PMID 15590629 DOI: 10.1074/Jbc.M413014200 |
0.485 |
|
| 2005 |
Iwata K, Luo J, Penn RB, Benovic JL. Bimodal regulation of the human H1 histamine receptor by G protein-coupled receptor kinase 2. The Journal of Biological Chemistry. 280: 2197-204. PMID 15542600 DOI: 10.1074/Jbc.M408834200 |
0.484 |
|
| 2004 |
Freyer AM, Billington CK, Penn RB, Hall IP. Extracellular matrix modulates beta2-adrenergic receptor signaling in human airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology. 31: 440-5. PMID 15205178 DOI: 10.1165/Rcmb.2003-0241Oc |
0.546 |
|
| 2003 |
Billington CK, Penn RB. Signaling and regulation of G protein-coupled receptors in airway smooth muscle. Respiratory Research. 4: 2. PMID 12648290 DOI: 10.1186/1465-9921-4-2 |
0.516 |
|
| 2003 |
Pascual RM, Awsare BK, Farber SA, Panettieri RA, Peters SP, Penn RB. Regulation of phospholipase A2 by interleulin-1 in human airway smooth muscle. Chest. 123: 433S-4S. PMID 12629024 DOI: 10.1378/Chest.123.3_Suppl.433S |
0.396 |
|
| 2003 |
Tilley SL, Hartney JM, Erikson CJ, Jania C, Nguyen M, Stock J, McNeisch J, Valancius C, Panettieri RA, Penn RB, Koller BH. Receptors and pathways mediating the effects of prostaglandin E2 on airway tone. American Journal of Physiology. Lung Cellular and Molecular Physiology. 284: L599-606. PMID 12618422 DOI: 10.1152/Ajplung.00324.2002 |
0.492 |
|
| 2003 |
Goncharova EA, Billington CK, Irani C, Vorotnikov AV, Tkachuk VA, Penn RB, Krymskaya VP, Panettieri RA. Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration. American Journal of Respiratory Cell and Molecular Biology. 29: 19-27. PMID 12600820 DOI: 10.1165/Rcmb.2002-0254Oc |
0.489 |
|
| 2002 |
Ammit AJ, Lazaar AL, Irani C, O'Neill GM, Gordon ND, Amrani Y, Penn RB, Panettieri RA. Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists. American Journal of Respiratory Cell and Molecular Biology. 26: 465-74. PMID 11919083 DOI: 10.1165/Ajrcmb.26.4.4681 |
0.437 |
|
| 2002 |
Billington CK, Penn RB. m3 muscarinic acetylcholine receptor regulation in the airway. American Journal of Respiratory Cell and Molecular Biology. 26: 269-72. PMID 11867333 DOI: 10.1165/Ajrcmb.26.3.F232 |
0.477 |
|
| 2002 |
Pascual RM, Billington CK, Hall IP, Panettieri RA, Fish JE, Peters SP, Penn RB. Mechanisms of cytokine effects on G protein-coupled receptor-mediated signaling in airway smooth muscle. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L1425-35. PMID 11704539 DOI: 10.1152/Ajplung.2001.281.6.L1425 |
0.564 |
|
| 2001 |
Penn RB, Pascual RM, Kim YM, Mundell SJ, Krymskaya VP, Panettieri RA, Benovic JL. Arrestin specificity for G protein-coupled receptors in human airway smooth muscle. The Journal of Biological Chemistry. 276: 32648-56. PMID 11418617 DOI: 10.1074/Jbc.M104143200 |
0.507 |
|
| 2001 |
Billington CK, Pascual RM, Hawkins ML, Penn RB, Hall IP. Interleukin-1beta and rhinovirus sensitize adenylyl cyclase in human airway smooth-muscle cells. American Journal of Respiratory Cell and Molecular Biology. 24: 633-9. PMID 11350835 DOI: 10.1165/Ajrcmb.24.5.4215 |
0.479 |
|
| 2001 |
Ammit AJ, Hastie AT, Edsall LC, Hoffman RK, Amrani Y, Krymskaya VP, Kane SA, Peters SP, Penn RB, Spiegel S, Panettieri RA. Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1212-4. PMID 11344091 DOI: 10.1096/Fj.00-0742Fje |
0.445 |
|
| 2001 |
Mundell SJ, Olah ME, Panettieri J, Benovic JL, Penn RB. Regulation of g protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine American Journal of Respiratory Cell and Molecular Biology. 24: 155-163. PMID 11159049 DOI: 10.1165/Ajrcmb.24.2.4243 |
0.527 |
|
| 2001 |
Penn RB, Pronin AN, Benovic JL. Regulation of G protein-coupled receptor kinases. Trends in Cardiovascular Medicine. 10: 81-9. PMID 11150735 DOI: 10.1016/S1050-1738(00)00053-0 |
0.459 |
|
| 2001 |
Ammit AJ, Hoffman RK, Amrani Y, Lazaar AL, Hay DW, Torphy TJ, Penn RB, Panettieri RA. Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells. Modulation by cyclic adenosine monophosphate. American Journal of Respiratory Cell and Molecular Biology. 23: 794-802. PMID 11104733 DOI: 10.1165/Ajrcmb.23.6.4184 |
0.397 |
|
| 2000 |
Krymskaya VP, Orsini MJ, Eszterhas AJ, Brodbeck KC, Benovic JL, Panettieri RA, Penn RB. Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 23: 546-54. PMID 11017921 DOI: 10.1165/Ajrcmb.23.4.4115 |
0.53 |
|
| 2000 |
Ramos-Ruiz R, Penela P, Penn RB, Mayor F. Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells. Circulation. 101: 2083-9. PMID 10790351 DOI: 10.1161/01.Cir.101.17.2083 |
0.361 |
|
| 2000 |
Eckhart AD, Duncan SJ, Penn RB, Benovic JL, Lefkowitz RJ, Koch WJ. Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart. Circulation Research. 86: 43-50. PMID 10625304 DOI: 10.1161/01.Res.86.1.43 |
0.371 |
|
| 1999 |
Orsini MJ, Krymskaya VP, Eszterhas AJ, Benovic JL, Panettieri RA, Penn RB. MAPK superfamily activation in human airway smooth muscle: mitogenesis requires prolonged p42/p44 activation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L479-L488. PMID 29592441 DOI: 10.1152/Ajplung.1999.277.3.L479 |
0.471 |
|
| 1999 |
Billington CK, Hall IP, Mundell SJ, Parent JL, Panettieri RA, Benovic JL, Penn RB. Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle. American Journal of Respiratory Cell and Molecular Biology. 21: 597-606. PMID 10536119 DOI: 10.1165/Ajrcmb.21.5.3759 |
0.522 |
|
| 1999 |
Krymskaya VP, Penn RB, Orsini MJ, Scott PH, Plevin RJ, Walker TR, Eszterhas AJ, Amrani Y, Chilvers ER, Panettieri RA. Phosphatidylinositol 3-kinase mediates mitogen-induced human airway smooth muscle cell proliferation American Journal of Physiology - Lung Cellular and Molecular Physiology. 277. PMID 10409232 DOI: 10.1152/Ajplung.1999.277.1.L65 |
0.532 |
|
| 1998 |
Penn RB, Panettieri RA, Benovic JL. Mechanisms of acute desensitization of the β2AR-adenylyl cyclase pathway in human airway smooth muscle American Journal of Respiratory Cell and Molecular Biology. 19: 338-348. PMID 9698608 DOI: 10.1165/Ajrcmb.19.2.3025 |
0.605 |
|
| 1998 |
Kallal L, Gagnon AW, Penn RB, Benovic JL. Visualization of agonist-induced sequestration and down-regulation of a green fluorescent protein-tagged β2-adrenergic receptor Journal of Biological Chemistry. 273: 322-328. PMID 9417083 DOI: 10.1074/Jbc.273.1.322 |
0.424 |
|
| 1997 |
Goodman OB, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH, Benovic JL. Role of arrestins in G-protein-coupled receptor endocytosis. Advances in Pharmacology (San Diego, Calif.). 42: 429-33. PMID 9327931 DOI: 10.1016/S1054-3589(08)60780-2 |
0.463 |
|
| 1997 |
Kelsen SG, Anakwe OO, Aksoy MO, Reddy PJ, Dhanesekaran N, Penn R, Benovic JL. Chronic effects of catecholamines on the beta 2-adrenoreceptor system in cultured human airway epithelial cells. The American Journal of Physiology. 272: L916-24. PMID 9176257 DOI: 10.1152/ajplung.1997.272.5.l916 |
0.319 |
|
| 1996 |
Penn RB, Shaver JR, Zangrilli JG, Pollice M, Fish JE, Peters SP, Benovic JL. Effects of inflammation and acute beta-agonist inhalation on beta 2-AR signaling in human airways. The American Journal of Physiology. 271: L601-8. PMID 8897908 DOI: 10.1152/Ajplung.1996.271.4.L601 |
0.405 |
|
| 1996 |
Penn RB, Frielle T, McCullough JR, Aberg G, Benovic JL. Comparison of R-, S-, and RS-Albuterol Interaction with Human β1- and β2-Adrenergic Receptors Clinical Reviews in Allergy and Immunology. 14: 37-45. PMID 8866170 DOI: 10.1007/Bf02772201 |
0.341 |
|
| 1996 |
Goodman OB, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH, Benovic JL. Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature. 383: 447-50. PMID 8837779 DOI: 10.1038/383447A0 |
0.446 |
|
| 1994 |
Penn RB, Kelsen SG, Benovic JL. Regulation of beta-agonist- and prostaglandin E2-mediated adenylyl cyclase activity in human airway epithelial cells American Journal of Respiratory Cell and Molecular Biology. 11: 496-505. PMID 7917318 DOI: 10.1165/Ajrcmb.11.4.7917318 |
0.469 |
|
| Show low-probability matches. |