Izidore Lossos - Publications

Affiliations: 
University of Miami, Coral Gables, FL 
Area:
Oncology, Pharmacology, Cell Biology

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Jiang X, Lu X, Gentles AJ, Zhao D, Wander SA, Zhang Y, Natkunam Y, Slingerland J, Reis IM, Rabinovich B, Abdulreda MH, Moy VT, Lossos IS. HGAL inhibits lymphoma dissemination by interacting with multiple Cytoskeletal proteins. Blood Advances. PMID 34543391 DOI: 10.1182/bloodadvances.2021004304  0.4
2021 Chapman J, Verdun RE, Lossos IS. Low LIM-domain only 2 (LMO2) expression in aggressive B cell lymphoma correlates with and / rearrangements, especially in germinal center cell-type tumors. Leukemia & Lymphoma. 1-4. PMID 33988072 DOI: 10.1080/10428194.2021.1927020  0.342
2021 Alvarez-Lesmes J, Chapman JR, Cassidy D, Zhou Y, Garcia-Buitrago M, Montgomery EA, Lossos IS, Sussman D, Poveda J. Gastrointestinal Tract Lymphomas: A Review of the Most Commonly Encountered Lymphomas. Archives of Pathology & Laboratory Medicine. PMID 33836528 DOI: 10.5858/arpa.2020-0661-RA  0.327
2020 Poveda J, Cassidy DP, Zhou Y, Alderuccio JP, Lossos IS, Vega F, Chapman J. Expression of germinal center cell markers by extranodal marginal zone lymphomas of MALT type within colonized follicles, a diagnostic pitfall with follicular lymphoma. Leukemia & Lymphoma. 1-7. PMID 33283568 DOI: 10.1080/10428194.2020.1855347  0.376
2020 Raboso-Gallego J, Casado-García A, Jiang X, Isidro-Hernández M, Gentles AJ, Zhao S, Natkunam Y, Blanco O, Domínguez V, Pintado B, De Las Rivas J, Alonso-López D, Vicente-Duenas C, Lossos IS, Sanchez-Garcia I. Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice. Blood. PMID 33024996 DOI: 10.1182/blood.2020004996  0.384
2019 Parvin S, Ramirez-Labrada A, Aumann S, Lu X, Weich N, Santiago G, Cortizas EM, Sharabi E, Zhang Y, Sanchez-Garcia I, Gentles AJ, Roberts E, Bilbao-Cortes D, Vega F, Chapman JR, ... ... Lossos IS, et al. LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL. Cancer Cell. PMID 31447348 DOI: 10.1016/j.ccell.2019.07.007  0.308
2019 Florindez J, Alderuccio JP, Lossos I. Plasmablastic Lymphoma: Survival Analysis of a SEER Database (2010-2016) Clinical Lymphoma Myeloma and Leukemia. 19: S259-S260. DOI: 10.1016/J.Clml.2019.07.174  0.326
2019 Morschhauser F, Ghosh N, Lossos I, Palomba M, Mehta A, Casasnovas O, Stevens D, Chitra S, Knapp A, Nielsen T, Oestergaard M, Wenger M, Salles G. EFFICACY AND SAFETY OF OBINUTUZUMAB + LENALIDOMIDE + ATEZOLIZUMAB IN PATIENTS WITH RELAPSED OR REFRACTORY FOLLICULAR LYMPHOMA: PRIMARY ANALYSIS OF A PHASE 1B/2 TRIAL Hematological Oncology. 37: 113-114. DOI: 10.1002/Hon.74_2629  0.319
2018 Algashaamy K, Tan Y, Mackrides N, Alencar A, Peng JH, Rosenblatt J, Alderuccio JP, Lossos IS, Vega F, Chapman J. Splenic B-Cell Lymphomas with Diffuse Cyclin D1 Protein Expression and Increased Prolymphocytic Cells: A Previously Unrecognized Diagnostic Pitfall. Case Reports in Hematology. 2018: 5761953. PMID 30363761 DOI: 10.1155/2018/5761953  0.328
2018 Qu C, Kunkalla K, Vaghefi A, Frederiksen JK, Liu Y, Chapman JR, Blonska M, Bernal-Mizrachi L, Alderuccio JP, Lossos IS, Landgraf R, Vega F. Smoothened Stabilizes and Protects TRAF6 from Degradation: A Novel Non-Canonical Role of Smoothened with Implications in Lymphoma Biology. Cancer Letters. PMID 30165192 DOI: 10.1016/J.Canlet.2018.08.020  0.314
2018 Lu X, Fernando T, Lossos C, Yusufova N, Liu F, Fontán L, Durant M, Geng H, Melnick J, Luo Y, Vega F, Moy V, Inghirami G, Nimer S, Melnick AM, ... Lossos IS, et al. PRMT5 interacts with the BCL6 oncoprotein and is required for germinal center formation and lymphoma cell survival. Blood. PMID 30082494 DOI: 10.1182/Blood-2018-02-831438  0.47
2018 Verdun RE, Parvin S, Ramirez Labrada A, Santiago GE, Elena CM, Eden S, Shlomzion A, Yu Z, Sanchez-Garcia I, Vega F, Chapman-Fredricks JR, Lossos IS. LMO2 Facilitates Synthetic Lethality after PARP Inhibition (PARPi) in Diffuse Large B-Cell Lymphoma (DLBCL) Blood. 132: 674-674. DOI: 10.1182/BLOOD-2018-99-110825  0.396
2017 Kunder CA, Roncador G, Advani RH, Gualco G, Bacchi CE, Sabile JM, Lossos IS, Nie K, Tibshirani RJ, Green MR, Alizadeh AA, Natkunam Y. KLHL6 Is Preferentially Expressed in Germinal Center-Derived B-Cell Lymphomas. American Journal of Clinical Pathology. PMID 29140403 DOI: 10.1093/Ajcp/Aqx099  0.313
2017 Guo X, Koff JL, Moffitt AB, Cinar M, Ramachandiran S, Chen Z, Switchenko JM, Mosunjac M, Neill SG, Mann KP, Bagirov M, Du Y, Natkunam Y, Khoury HJ, Rossi MR, ... ... Lossos IS, et al. Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype. Oncogene. PMID 28368397 DOI: 10.1038/Onc.2017.90  0.384
2017 Bhatt S, Parvin S, Zhang Y, Cho HM, Kunkalla K, Vega F, Timmerman JM, Shin SU, Rosenblatt JD, Lossos IS. Anti-CD20-Interleukin-21 fusokine targets malignant B-cells via direct apoptosis and NK-cell dependent cytotoxicity. Blood. PMID 28137826 DOI: 10.1182/blood-2016-09-738211  0.444
2016 Mackrides N, Campuzano-Zuluaga G, Maque-Acosta Y, Moul A, Hijazi N, Ikpatt FO, Levy R, Verdun RE, Kunkalla K, Natkunam Y, Lossos IS, Vega F, Chapman J. Epstein-Barr virus-positive follicular lymphoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 27982024 DOI: 10.1038/modpathol.2016.214  0.322
2016 Bhatt S, Sarosiek KA, Lossos IS. Interleukin 21 - its potential role in the therapy of B-cell lymphomas. Leukemia & Lymphoma. 1-13. PMID 27405876 DOI: 10.1080/10428194.2016.1201568  0.723
2016 Matthews JM, Bhatt S, Patricelli MP, Nomanbhoy TK, Jiang X, Natkunam Y, Gentles AJ, Martinez E, Zhu D, Chapman JR, Cortizas E, Shyam R, Chinichian S, Advani R, Tan L, ... ... Lossos IS, et al. Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma. Blood. PMID 27151888 DOI: 10.1182/Blood-2016-02-696856  0.659
2016 Healy JA, Nugent A, Rempel RE, Moffitt AB, Davis NS, Jiang X, Shingleton JR, Zhang J, Love C, Datta J, McKinney ME, Zhang TJ, Wettschureck N, Offermanns S, Walzer KA, ... ... Lossos IS, et al. GNA13 loss in germinal center B cells leads to impaired apoptosis and GC B cell persistence and promotes lymphoma in vivo. Blood. PMID 26989201 DOI: 10.1182/Blood-2015-07-659938  0.338
2015 Agarwal NK, Kim CH, Kunkalla K, Konno H, Tjendra Y, Kwon D, Blonska M, Kozloski GA, Moy VT, Verdun RE, Barber GN, Lossos IS, Vega F. Active IKKβ promotes the stability of GLI1 oncogene in diffuse large B-cell lymphoma. Blood. PMID 26603838 DOI: 10.1182/Blood-2015-07-658781  0.306
2015 Bhatt S, Matthews J, Parvin S, Sarosiek KA, Zhao D, Jiang X, Isik E, Letai A, Lossos IS. Direct and immune-mediated cytotoxicity of interleukin-21 contributes to antitumor effects in mantle cell lymphoma. Blood. 126: 1555-64. PMID 26194763 DOI: 10.1182/Blood-2015-01-624585  0.767
2015 Zhu D, Bhatt S, Lu X, Guo F, Veelken H, Hsu DK, Liu FT, Alvarez Cubela S, Kunkalla K, Vega F, Chapman-Fredricks JR, Lossos IS. Chlamydophila psittaci-negative ocular adnexal marginal zone lymphomas express self polyreactive B-cell receptors. Leukemia. 29: 1587-99. PMID 25676418 DOI: 10.1038/Leu.2015.39  0.385
2015 Bhatt S, Matthews J, Parvin S, Sarosiek KA, Zhao D, Jiang X, Isik E, Letai A, Lossos IS. Direct and immune-mediated cytotoxicity of interleukin-21 contributes to antitumor effects in mantle cell lymphoma Blood. 126: 1555-1564. DOI: 10.1182/blood-2015-01-624585  0.719
2015 Fuente Mdl, Fabregas J, Markoe A, Lossos I. RARE-03PRIMARY DURAL LYMPHOMA: SINGLE INSTITUTION STUDY OF TREATMENT AND OUTCOME Neuro-Oncology. 17: v201.3-v201. DOI: 10.1093/Neuonc/Nov232.03  0.346
2014 Green MR, Vicente-Dueñas C, Romero-Camarero I, Long Liu C, Dai B, González-Herrero I, García-Ramírez I, Alonso-Escudero E, Iqbal J, Chan WC, Campos-Sanchez E, Orfao A, Pintado B, Flores T, Blanco O, ... ... Lossos IS, et al. Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma. Nature Communications. 5: 3904. PMID 24887457 DOI: 10.1038/Ncomms4904  0.401
2014 Lossos C, Bayraktar S, Weinzierl E, Younes SF, Hosein PJ, Tibshirani RJ, Sutton Posthumus J, DeAngelis LM, Raizer J, Schiff D, Abrey L, Natkunam Y, Lossos IS. LMO2 and BCL6 are associated with improved survival in primary central nervous system lymphoma. British Journal of Haematology. 165: 640-8. PMID 24571259 DOI: 10.1111/Bjh.12801  0.309
2014 Friedberg JW, Mahadevan D, Cebula E, Persky D, Lossos I, Agarwal AB, Jung J, Burack R, Zhou X, Leonard EJ, Fingert H, Danaee H, Bernstein SH. Phase II study of alisertib, a selective Aurora A kinase inhibitor, in relapsed and refractory aggressive B- and T-cell non-Hodgkin lymphomas. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 44-50. PMID 24043741 DOI: 10.1200/Jco.2012.46.8793  0.433
2014 Bhatt S, Sarosiek K, Parvin S, Matthews JM, Zhao D, Lossos IS. Interleukin-21 Potently Induces Direct and Indirect Cytotoxicity of Mantle Cell Lymphoma Blood. 124: 1776-1776. DOI: 10.1182/Blood.V124.21.1776.1776  0.766
2014 Koff JL, Guo X, Ramachandiran S, Switchenko JM, Mosunjac MB, Neill SG, Mann K, Bagirov M, Flowers CR, Lossos IS, Natkunam Y, Kowalski J, Bernal-Mizrachi L. Putting the ‘Activate’ in Activated B Cell-like Diffuse Large B Cell Lymphoma: A Role for the Noncanonical NF-κB Pathway Clinical Lymphoma Myeloma and Leukemia. 14: S143. DOI: 10.1016/J.Clml.2014.06.079  0.341
2013 Bhatt S, Ashlock BM, Natkunam Y, Sujoy V, Chapman JR, Ramos JC, Mesri EA, Lossos IS. CD30 targeting with brentuximab vedotin: a novel therapeutic approach to primary effusion lymphoma. Blood. 122: 1233-42. PMID 23838350 DOI: 10.1182/Blood-2013-01-481713  0.345
2013 Bertolo C, Roa S, Sagardoy A, Mena-Varas M, Robles EF, Martinez-Ferrandis JI, Sagaert X, Tousseyn T, Orta A, Lossos IS, Amar S, Natkunam Y, Briones J, Melnick A, Malumbres R, et al. LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas. British Journal of Haematology. 162: 621-30. PMID 23795761 DOI: 10.1111/Bjh.12440  0.389
2013 Romero-Camarero I, Jiang X, Natkunam Y, Lu X, Vicente-Dueñas C, Gonzalez-Herrero I, Flores T, Garcia JL, McNamara G, Kunder C, Zhao S, Segura V, Fontan L, Martínez-Climent JA, García-Criado FJ, ... ... Lossos IS, et al. Germinal centre protein HGAL promotes lymphoid hyperplasia and amyloidosis via BCR-mediated Syk activation. Nature Communications. 4: 1338. PMID 23299888 DOI: 10.1038/Ncomms2334  0.354
2013 Kohrt HE, Godwin JE, Lossos IS, Williams ME, Timmerman J, Link BK, Goldberg SM, McGirr A, Kurland JF, Wigginton JM, Cohen LJ, Levy R. A phase Ib, open-label, multicenter study of urelumab (BMS-663513) in combination with rituximab in subjects with relapsed/refractory B-cell malignancies. Journal of Clinical Oncology. 31: TPS3108-TPS3108. DOI: 10.1200/JCO.2013.31.15_SUPPL.TPS3108  0.314
2013 Palomero T, Couronne L, Khiabanian H, Kim M, Ambesi A, Carpenter Z, Abate F, Allegretta M, Lossos IS, Nicolas C, Balbin M, Bastard C, Bhagat G, Piris MAA, Campo E, et al. Recurrent Rhoa Mutations In Peripheral T-Cell Lymphoma Blood. 122: 846-846. DOI: 10.1182/Blood.V122.21.846.846  0.303
2013 Matthews JM, Tan L, Bhatt S, Patricelli M, Nomanbhoy T, Zhang J, Jiang X, Natkunam Y, Choi HG, Gentles AJ, Martinez E, Zhu D, Chapman JR, Shyam RM, Chinichian S, ... ... Lossos IS, et al. Germinal Center Kinase Regulates The Proliferation and Survival Of Diffuse Large B-Cell Lymphoma Blood. 122: 643-643. DOI: 10.1182/Blood.V122.21.643.643  0.67
2013 Bhatt S, Zhu D, Jiang X, Shin S, Timmerman JM, Rosenblatt JD, Lossos IS. Targeting B-Cell Malignancies With Anti-CD20-Interleukin-21 Fusokine Blood. 122: 377-377. DOI: 10.1182/blood.V122.21.377.377  0.446
2012 Vicente-Dueñas C, Fontán L, Gonzalez-Herrero I, Romero-Camarero I, Segura V, Aznar MA, Alonso-Escudero E, Campos-Sanchez E, Ruiz-Roca L, Barajas-Diego M, Sagardoy A, Martinez-Ferrandis JI, Abollo-Jimenez F, Bertolo C, Peñuelas I, ... ... Lossos IS, et al. Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 10534-9. PMID 22689981 DOI: 10.1073/pnas.1204127109  0.403
2012 Cubedo E, Gentles AJ, Huang C, Natkunam Y, Bhatt S, Lu X, Jiang X, Romero-Camarero I, Freud A, Zhao S, Bacchi CE, Martínez-Climent JA, Sánchez-García I, Melnick A, Lossos IS. Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma. Blood. 119: 5478-91. PMID 22517897 DOI: 10.1182/Blood-2012-01-403154  0.384
2012 Braggio E, Dogan A, Keats JJ, Chng WJ, Huang G, Matthews JM, Maurer MJ, Law ME, Bosler DS, Barrett M, Lossos IS, Witzig TE, Fonseca R. Genomic analysis of marginal zone and lymphoplasmacytic lymphomas identified common and disease-specific abnormalities. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 25: 651-60. PMID 22301699 DOI: 10.1038/Modpathol.2011.213  0.538
2012 Jiang X, Lu X, Lossos IS. Interaction of HGAL with Grb2 Enhances RhoA and B-Cell Receptor Signaling Blood. 120: 681-681. DOI: 10.1182/BLOOD.V120.21.681.681  0.389
2011 Zhu D, Lossos C, Chapman-Fredricks JR, Matthews JM, Ikpatt OF, Ruiz P, Lossos IS. Biased use of the IGHV4 family and evidence for antigen selection in Chlamydophila psittaci-negative ocular adnexal extranodal marginal zone lymphomas. Plos One. 6: e29114. PMID 22216179 DOI: 10.1371/Journal.Pone.0029114  0.576
2011 Morton LM, Cerhan JR, Hartge P, Vasef MA, Neppalli VT, Natkunam Y, Dogan A, Dave BJ, Jain S, Levy R, Lossos IS, Cozen W, Davis S, Schenk MJ, Maurer MJ, et al. Immunostaining to identify molecular subtypes of diffuse large B-cell lymphoma in a population-based epidemiologic study in the pre-rituximab era. International Journal of Molecular Epidemiology and Genetics. 2: 245-52. PMID 21915363  0.324
2011 Cubedo E, Maurin M, Jiang X, Lossos IS, Wright KL. PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL. The Febs Journal. 278: 3065-75. PMID 21722313 DOI: 10.1111/j.1742-4658.2011.08227.x  0.368
2011 Alizadeh AA, Gentles AJ, Alencar AJ, Liu CL, Kohrt HE, Houot R, Goldstein MJ, Zhao S, Natkunam Y, Advani RH, Gascoyne RD, Briones J, Tibshirani RJ, Myklebust JH, Plevritis SK, ... Lossos IS, et al. Prediction of survival in diffuse large B-cell lymphoma based on the expression of 2 genes reflecting tumor and microenvironment. Blood. 118: 1350-8. PMID 21670469 DOI: 10.1182/Blood-2011-03-345272  0.344
2011 Malumbres R, Fresquet V, Roman-Gomez J, Bobadilla M, Robles EF, Altobelli GG, Calasanz MJ, Smeland EB, Aznar MA, Agirre X, Martin-Palanco V, Prosper F, Lossos IS, Martinez-Climent JA. LMO2 expression reflects the different stages of blast maturation and genetic features in B-cell acute lymphoblastic leukemia and predicts clinical outcome. Haematologica. 96: 980-6. PMID 21459790 DOI: 10.3324/haematol.2011.040568  0.313
2011 Baecklund E, Backlin C, Mansouri M, Klareskog L, Askling J, Iliadou AN, Enblad G, Lossos IS, Natkunam Y, Rosenquist R. LMO2 protein expression predicts survival in patients with rheumatoid arthritis and diffuse large B-cell lymphoma. Leukemia & Lymphoma. 52: 1146-9. PMID 21375434 DOI: 10.3109/10428194.2011.559801  0.306
2011 Morgensztern D, Walker GR, Koniaris LG, Lossos IS. Lack of survival improvement in patients with peripheral T-cell lymphoma: a Surveillance, Epidemiology, and End Results analysis. Leukemia & Lymphoma. 52: 194-204. PMID 21281235 DOI: 10.3109/10428194.2010.542596  0.301
2011 Jiang X, Romero-Camarero I, Lu X, Vicente-Dueñas C, Gonzalez-Herrero I, Flores T, Garcia JL, McNamara G, Kunder C, Natkunam Y, Segura V, Fontan-Gabas L, Martinez-Climent JA, Alizadeh AA, Cobaleda C, ... ... Lossos IS, et al. HGAL-a Germinal Center Specific Protein, Enhances B-Cell Receptor Signaling by Activation of Syk, Leading to Follicular Lymphoproliferation Blood. 118: 584-584. DOI: 10.1182/Blood.V118.21.584.584  0.393
2011 Bhatt S, Ashlock B, Natkunam Y, Ramos JC, Mesri E, Lossos IS. Preclinical Activity of Brentuximab Vedotin (SGN-35) in Primary Effusion Lymphoma (PEL), Blood. 118: 3728-3728. DOI: 10.1182/Blood.V118.21.3728.3728  0.322
2011 Bhatt S, Ashlock B, Toomey N, Mesri E, Ramos JC, Lossos IS. Synergistic Preclinical Activity of Bortezomib with Suberoylanilide Hydroxamic Acid (SAHA) in Primary Effusion Lymphoma (PEL) Blood. 118: 1650-1650. DOI: 10.1182/Blood.V118.21.1650.1650  0.355
2011 Bertolo C, Malumbres R, Sagardoy A, Robles EF, Martinez-Ferrandis JI, Roa S, Lossos IS, Sagaert X, Melnick A, Amar S, Martinez-Climent JA. LITAF, a BCL6 Target Gene, Regulates Autophagia in B Cells and Is Essential for T-Cell Dependent Humoral Responses Blood. 118: 1391-1391. DOI: 10.1182/Blood.V118.21.1391.1391  0.371
2010 Lossos IS. BLIMP1 against lymphoma: The verdict is reached. Cancer Cell. 18: 537-9. PMID 21156275 DOI: 10.1016/j.ccr.2010.11.029  0.39
2010 Jiang X, Lu X, McNamara G, Liu X, Cubedo E, Sarosiek KA, Sánchez-García I, Helfman DM, Lossos IS. HGAL, a germinal center specific protein, decreases lymphoma cell motility by modulation of the RhoA signaling pathway. Blood. 116: 5217-27. PMID 20844236 DOI: 10.1182/Blood-2010-04-281568  0.676
2010 Durnick DK, Law ME, Maurer MJ, Natkunam Y, Levy R, Lossos IS, Kurtin PJ, McPhail ED. Expression of LMO2 is associated with t(14;18)/IGH-BCL2 fusion but not BCL6 translocations in diffuse large B-cell lymphoma. American Journal of Clinical Pathology. 134: 278-81. PMID 20660332 DOI: 10.1309/AJCPATUP1D0HGCUG  0.351
2010 Sarosiek KA, Cavallin LE, Bhatt S, Toomey NL, Natkunam Y, Blasini W, Gentles AJ, Ramos JC, Mesri EA, Lossos IS. Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma. Proceedings of the National Academy of Sciences of the United States of America. 107: 13069-74. PMID 20615981 DOI: 10.1073/Pnas.1002985107  0.669
2010 Anderson MW, Zhao S, Ai WZ, Tibshirani R, Levy R, Lossos IS, Natkunam Y. C-C chemokine receptor 1 expression in human hematolymphoid neoplasia. American Journal of Clinical Pathology. 133: 473-83. PMID 20154287 DOI: 10.1309/Ajcp1Ta3Floqtmhf  0.336
2010 Sarosiek KA, Malumbres R, Nechushtan H, Gentles AJ, Avisar E, Lossos IS. Novel IL-21 signaling pathway up-regulates c-Myc and induces apoptosis of diffuse large B-cell lymphomas. Blood. 115: 570-80. PMID 19965678 DOI: 10.1182/Blood-2009-08-239996  0.735
2010 Matthews JM, Natkunam Y, Srinivasan S, Patricelli M, Nomanbhoy T, Cerchietti L, Melnick AM, Lossos IS. STAT3, Constitutively Activated In ABC-Like DLBCL, Regulates Expression of the Prognostic Factor Cyclin D2 Blood. 116: 705-705. DOI: 10.1182/Blood.V116.21.705.705  0.661
2010 Cubedo E, Maurin M, Wright K, Lossos IS. BLIMP1 Downregulates Expression of, LMO2 and HGAL, Proteins Highly Expressed In Germinal Center B Cells and Germinal Center-Derived Lymphomas Blood. 116: 4133-4133. DOI: 10.1182/BLOOD.V116.21.4133.4133  0.4
2009 Azambuja D, Lossos IS, Biasoli I, Morais JC, Britto L, Scheliga A, Pulcheri W, Natkunam Y, Spector N. Human germinal center-associated lymphoma protein expression is associated with improved failure-free survival in Brazilian patients with classical Hodgkin lymphoma. Leukemia & Lymphoma. 50: 1830-6. PMID 19883310 DOI: 10.1182/Blood.V114.22.4632.4632  0.39
2009 Sarosiek KA, Nechushtan H, Lu X, Rosenblatt JD, Lossos IS. Interleukin-4 distinctively modifies responses of germinal centre-like and activated B-cell-like diffuse large B-cell lymphomas to immuno-chemotherapy. British Journal of Haematology. 147: 308-18. PMID 19694722 DOI: 10.1111/J.1365-2141.2009.07851.X  0.738
2009 Malumbres R, Sarosiek KA, Cubedo E, Ruiz JW, Jiang X, Gascoyne RD, Tibshirani R, Lossos IS. Differentiation stage-specific expression of microRNAs in B lymphocytes and diffuse large B-cell lymphomas. Blood. 113: 3754-64. PMID 19047678 DOI: 10.1182/Blood-2008-10-184077  0.622
2009 Jiang X, Lu X, Mcnamara G, Liu X, Sarosiek KA, Helfman DM, Lossos IS. HGAL, a Lymphoma Prognostic Biomarker, Regulates Lymphocyte and Lymphoma Cell Motility by Modulation of RhoA Signaling Pathway. Blood. 114: 316-316. DOI: 10.1182/Blood.V114.22.316.316  0.698
2008 Lu X, Malumbres R, Shields B, Jiang X, Sarosiek KA, Natkunam Y, Tiganis T, Lossos IS. PTP1B is a negative regulator of interleukin 4-induced STAT6 signaling. Blood. 112: 4098-108. PMID 18716132 DOI: 10.1182/Blood-2008-03-148726  0.689
2008 Escalón MP, Lossos IS. Pharmacotherapy of large B-cell lymphoma. Expert Opinion On Pharmacotherapy. 9: 2247-58. PMID 18710350 DOI: 10.1517/14656566.9.13.2247  0.359
2008 Matthews JM, Moreno LI, Dennis J, Byrne GE, Ruiz P, Dubovy SR, Lossos IS. Ocular Adnexal Lymphoma: no evidence for bacterial DNA associated with lymphoma pathogenesis. British Journal of Haematology. 142: 246-9. PMID 18492114 DOI: 10.1111/J.1365-2141.2008.07112.X  0.533
2008 Xie X, Sundram U, Natkunam Y, Kohler S, Hoppe RT, Kim YH, Cook JR, Hammel J, Swerdlow SH, Guitart J, Smith MD, Bosler D, Listinsky C, Lossos IS, Hsi ED. Expression of HGAL in primary cutaneous large B-cell lymphomas: evidence for germinal center derivation of primary cutaneous follicular lymphoma. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 653-9. PMID 18264083 DOI: 10.1038/modpathol.2008.30  0.377
2008 Lossos IS. Diffuse large B cell lymphoma: from gene expression profiling to prediction of outcome. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 14: 108-11. PMID 18162230 DOI: 10.1016/j.bbmt.2007.10.020  0.335
2008 Natkunam Y, Farinha P, Hsi ED, Hans CP, Tibshirani R, Sehn LH, Connors JM, Gratzinger D, Rosado M, Zhao S, Pohlman B, Wongchaowart N, Bast M, Avigdor A, Schiby G, ... ... Lossos IS, et al. LMO2 protein expression predicts survival in patients with diffuse large B-cell lymphoma treated with anthracycline-based chemotherapy with and without rituximab. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 447-54. PMID 18086797 DOI: 10.1200/Jco.2007.13.0690  0.338
2008 Sarosiek KA, Nechushtan H, Avisar E, Lossos IS. Interleukin-21 Induces Cell Cycle Arrest and Apoptosis of Diffuse Large B-Cell Lymphomas (DLBCL) Via Activation of STAT3 and Upregulation of C-Myc Blood. 112: 601-601. DOI: 10.1182/Blood.V112.11.601.601  0.732
2007 Lu X, Chen J, Malumbres R, Cubedo Gil E, Helfman DM, Lossos IS. HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration. Blood. 110: 4268-77. PMID 17823310 DOI: 10.1182/blood-2007-04-087775  0.506
2007 Lossos IS. The endless complexity of lymphocyte differentiation and lymphomagenesis: IRF-4 downregulates BCL6 expression. Cancer Cell. 12: 189-91. PMID 17785200 DOI: 10.1016/j.ccr.2007.08.012  0.313
2007 Lossos IS, Morgensztern D, Blaya M, Alencar A, Pereira D, Rosenblatt J. Rituximab for treatment of chemoimmunotherapy naive marginal zone lymphoma. Leukemia & Lymphoma. 48: 1630-2. PMID 17701596 DOI: 10.1080/10428190701457949  0.32
2007 Lossos IS. IL-4 in lymphoma: does the target matter? Leukemia & Lymphoma. 48: 1261-3. PMID 17613751 DOI: 10.1080/10428190701385199  0.346
2007 Morgensztern D, Martin MG, Lossos IS. Gene expression profiling in diffuse large B-cell lymphoma. Leukemia & Lymphoma. 48: 669-82. PMID 17454624 DOI: 10.1080/10428190601186176  0.307
2007 Lu X, Chen J, Sasmono RT, Hsi ED, Sarosiek KA, Tiganis T, Lossos IS. T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6. Molecular and Cellular Biology. 27: 2166-79. PMID 17210636 DOI: 10.1128/Mcb.01234-06  0.736
2007 Fong T, Lossos I, Morgensztern D. Primary Non-Hodgkin’s Lymphoma of the Lung. Blood. 110: 4402-4402. DOI: 10.1182/Blood.V110.11.4402.4402  0.361
2007 Morgensztern D, Walker G, Koniaris L, Lossos IS. Lack of Survival Improvement in Patients with Large Cell Lymphomas of T-Cell Phenotype: A SEER Analysis Comparing Outcomes According to Phenotype and Year of Diagnosis. Blood. 110: 3577-3577. DOI: 10.1182/BLOOD.V110.11.3577.3577  0.302
2007 Lu X, Malumbres R, Tiganis T, Lossos IS. PTP1B, Distinctively Expressed in GCB-Like and ABC-Like DLBCL, Is a New Regulator of IL-4-STAT6 Intracellular Signaling. Blood. 110: 1558-1558. DOI: 10.1182/BLOOD.V110.11.1558.1558  0.478
2006 Natkunam Y, Zhao S, Mason DY, Chen J, Taidi B, Jones M, Hammer AS, Hamilton Dutoit S, Lossos IS, Levy R. The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas. Blood. 109: 1636-42. PMID 17038524 DOI: 10.1182/blood-2006-08-039024  0.383
2006 Natkunam Y, Hsi ED, Aoun P, Zhao S, Elson P, Pohlman B, Naushad H, Bast M, Levy R, Lossos IS. Expression of the human germinal center-associated lymphoma (HGAL) protein identifies a subset of classic Hodgkin lymphoma of germinal center derivation and improved survival. Blood. 109: 298-305. PMID 16954503 DOI: 10.1182/BLOOD-2006-04-014977  0.333
2006 Abdullah S, Morgensztern D, Rosado MF, Lossos IS. Primary lymphoblastic B-cell lymphoma of the cranial dura mater: a case report and review of the literature. Leukemia & Lymphoma. 46: 1651-7. PMID 16334908 DOI: 10.1080/10428190500215126  0.33
2006 Wiernik PH, Lossos I, Tuscano J, Justice G, Vose JM, Pietronigro D, Takeshita K, Ervin-Haynes A, Zeldis JB, Habermann TM. Preliminary Results from a Phase II Study of Lenalidomide Monotherapy in Relapsed/Refractory Aggressive Non-Hodgkin’s Lymphoma. Blood. 108: 531-531. DOI: 10.1182/Blood.V108.11.531.531  0.362
2006 Ramos JC, Ruiz P, Ratner L, Harjaj EW, Lossos I, Harrington WJ. IRF-4 and Interferon Resistance in Adult T-Cell Leukemia/Lymphoma. Blood. 108: 2531-2531. DOI: 10.1182/Blood.V108.11.2531.2531  0.447
2006 Sarosiek KA, Chen J, Pham DG, Nechushtan H, Avisar E, Kindsvogel W, Lossos IS. Interleukin-21-Induced Apoptosis and Cell Death of Diffuse Large B-Cell Lymphoma (DLBCL) Cell Lines and Primary Tumors Are Associated with an Induction of Bim. Blood. 108: 2503-2503. DOI: 10.1182/Blood.V108.11.2503.2503  0.721
2006 Chen J, Ding F, Helfman DM, Lossos IS. HGAL - A Germinal Center-Like Diffuse Large B-Cell Lymphoma Prognostic Biomarker Interacts with the Cytoskeleton and Influences Cell Migration. Blood. 108: 2022-2022. DOI: 10.1182/BLOOD.V108.11.2022.2022  0.486
2005 Lossos IS. Molecular pathogenesis of diffuse large B-cell lymphoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 6351-7. PMID 16155019 DOI: 10.1200/JCO.2005.05.012  0.341
2005 Natkunam Y, Lossos IS, Taidi B, Zhao S, Lu X, Ding F, Hammer AS, Marafioti T, Byrne GE, Levy S, Warnke RA, Levy R. Expression of the human germinal center-associated lymphoma (HGAL) protein, a new marker of germinal center B-cell derivation. Blood. 105: 3979-86. PMID 15677569 DOI: 10.1182/BLOOD-2004-08-3112  0.374
2005 Lu X, Nechushtan H, Ding F, Rosado MF, Singal R, Alizadeh AA, Lossos IS. Distinct IL-4-induced gene expression, proliferation, and intracellular signaling in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas. Blood. 105: 2924-32. PMID 15591113 DOI: 10.1182/blood-2004-10-3820  0.514
2005 Lossos IS, Lu X, Tiganis T. PTPN2, Distinctively Expressed in GCB-Like and ABC-Like DLBCL, Is the Nuclear Phosphatase of STAT6. Blood. 106: 418-418. DOI: 10.1182/BLOOD.V106.11.418.418  0.48
2004 Lossos IS, Lu X, Ding F, Rosado M, Alizadeh AA, Nechushtan H. Distinct IL-4 Intracellular Signaling in Germinal Center B-Cell like and Activated B-Cell like Diffuse Large B-Cell Lymphoma: Novel Opportunities for Therapeutic Interventions. Blood. 104: 244-244. DOI: 10.1182/blood.v104.11.244.244  0.514
2004 Nechushtan H, Rosenblatt JD, Lossos IS. IL-4 Affects Proliferation, Chemosensitivity-and Rituximab Sensitivity of Germinal Center B-Cell like (GCB) and Activated B-Cell like (ABC) Diffuse Large B-Cell Lymphoma Differently. Blood. 104: 242-242. DOI: 10.1182/blood.v104.11.242.242  0.529
2003 Lossos IS, Levy R. Diffuse large B-cell lymphoma: insights gained from gene expression profiling. International Journal of Hematology. 77: 321-9. PMID 12774918 DOI: 10.1007/BF02982638  0.345
2003 Lossos IS, Natkunam Y, Levy R, Lopez CD. Apoptosis stimulating protein of p53 (ASPP2) expression differs in diffuse large B-cell and follicular center lymphoma: correlation with clinical outcome. Leukemia & Lymphoma. 43: 2309-17. PMID 12613517 DOI: 10.1080/1042819021000040017  0.312
2003 Lossos IS, Alizadeh AA, Rajapaksa R, Tibshirani R, Levy R. HGAL is a novel interleukin-4-inducible gene that strongly predicts survival in diffuse large B-cell lymphoma. Blood. 101: 433-40. PMID 12509382 DOI: 10.1182/Blood-2002-06-1931  0.401
2001 Lossos IS, Jones CD, Warnke R, Natkunam Y, Kaizer H, Zehnder JL, Tibshirani R, Levy R. Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma. Blood. 98: 945-51. PMID 11493437 DOI: 10.1182/Blood.V98.4.945  0.3
2000 Lossos IS, Alizadeh AA, Eisen MB, Chan WC, Brown PO, Botstein D, Staudt LM, Levy R. Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas. Proceedings of the National Academy of Sciences of the United States of America. 97: 10209-13. PMID 10954754 DOI: 10.1073/Pnas.180316097  0.346
1998 Lossos IS, Breuer R, Shriki M, Or R. Peribronchial lymphocyte activation in bleomycin-induced lung injury. Life Sciences. 63: 1183-93. PMID 9763213 DOI: 10.1016/S0024-3205(98)00379-8  0.329
1996 Or R, Lossos IS, Hirschfeld E, Breuer R. Effect of interleukin-2 and interleukin-4 on lymphocytes from peribronchial lymphatic tissue. Experimental Lung Research. 22: 245-53. PMID 8706639 DOI: 10.3109/01902149609050850  0.406
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