| Year |
Citation |
Score |
| 2023 |
Wong D, Luo P, Oldfield LE, Gong H, Brunga L, Rabinowicz R, Subasri V, Chan C, Downs T, Farncombe KM, Luu B, Norman M, Sobotka JA, Uju P, Eagles J, ... ... Malkin D, et al. Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA. Cancer Discovery. PMID 37874259 DOI: 10.1158/2159-8290.CD-23-0456 |
0.311 |
|
| 2023 |
Subasri V, Light N, Kanwar N, Brzezinski J, Luo P, Hansford JR, Cairney E, Portwine C, Elser C, Finlay JL, Nichols KE, Alon N, Brunga L, Anson J, Kohlmann W, ... ... Malkin D, et al. Multiple Germline Events Contribute to Cancer Development in Patients with Li-Fraumeni Syndrome. Cancer Research Communications. 3: 738-754. PMID 37377903 DOI: 10.1158/2767-9764.CRC-22-0402 |
0.682 |
|
| 2023 |
Comitani F, Nash JO, Cohen-Gogo S, Chang AI, Wen TT, Maheshwari A, Goyal B, Tio ES, Tabatabaei K, Mayoh C, Zhao R, Ho B, Brunga L, Lawrence JEG, Balogh P, ... ... Malkin D, et al. Diagnostic classification of childhood cancer using multiscale transcriptomics. Nature Medicine. PMID 36932241 DOI: 10.1038/s41591-023-02221-x |
0.311 |
|
| 2023 |
Light N, Layeghifard M, Attery A, Subasri V, Zatzman M, Anderson ND, Hatkar R, Blay S, Chen D, Novokmet A, Fuligni F, Tran J, de Borja R, Agarwal H, Waldman L, ... ... Malkin D, et al. Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis. Nature Communications. 14: 77. PMID 36604421 DOI: 10.1038/s41467-022-35727-y |
0.341 |
|
| 2022 |
Villani A, Davidson S, Kanwar N, Lo WW, Li Y, Cohen-Gogo S, Fuligni F, Edward LM, Light N, Layeghifard M, Harripaul R, Waldman L, Gallinger B, Comitani F, Brunga L, ... ... Malkin D, et al. The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations. Nature Cancer. PMID 36585449 DOI: 10.1038/s43018-022-00474-y |
0.325 |
|
| 2022 |
Chung J, Negm L, Bianchi V, Stengs L, Das A, Liu ZA, Sudhaman S, Aronson M, Brunga L, Edwards M, Forster V, Komosa M, Davidson S, Lees J, Tomboc P, ... ... Malkin D, et al. Genomic Microsatellite Signatures Identify Germline Mismatch Repair Deficiency and Risk of Cancer Onset. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2102873. PMID 36240479 DOI: 10.1200/JCO.21.02873 |
0.304 |
|
| 2022 |
Chen JL, Miller DT, Schmidt LS, Malkin D, Korf BR, Eng C, Kwiatkowski DJ, Giannikou K. Mosaicism in Tumor Suppressor Gene Syndromes: Prevalence, Diagnostic Strategies, and Transmission Risk. Annual Review of Genomics and Human Genetics. 23: 331-361. PMID 36044908 DOI: 10.1146/annurev-genom-120121-105450 |
0.311 |
|
| 2022 |
Das A, Sudhaman S, Morgenstern D, Coblentz A, Chung J, Stone SC, Alsafwani N, Liu ZA, Karsaneh OAA, Soleimani S, Ladany H, Chen D, Zatzman M, Cabric V, Nobre L, ... ... Malkin D, et al. Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency. Nature Medicine. PMID 34992263 DOI: 10.1038/s41591-021-01581-6 |
0.334 |
|
| 2021 |
Kratz CP, Freycon C, Maxwell KN, Nichols KE, Schiffman JD, Evans DG, Achatz MI, Savage SA, Weitzel JN, Garber JE, Hainaut P, Malkin D. Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set: An International Agency for Research on Cancer TP53 Database Analysis. Jama Oncology. PMID 34709361 DOI: 10.1001/jamaoncol.2021.4398 |
0.3 |
|
| 2020 |
Kratz CP, Villani A, Nichols KE, Schiffman J, Malkin D. Cancer surveillance for individuals with Li-Fraumeni syndrome. European Journal of Human Genetics : Ejhg. PMID 32814850 DOI: 10.1038/S41431-020-00709-5 |
0.352 |
|
| 2020 |
Capaci V, Bascetta L, Fantuz M, Beznoussenko GV, Sommaggio R, Cancila V, Bisso A, Campaner E, Mironov AA, Wiśniewski JR, Ulloa Severino L, Scaini D, Bossi F, Lees J, Alon N, ... ... Malkin D, et al. Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome. Nature Communications. 11: 3945. PMID 32770028 DOI: 10.1038/S41467-020-17596-5 |
0.402 |
|
| 2020 |
Graziano F, Fischer NW, Bagaloni I, Di Bartolomeo M, Lonardi S, Vincenzi B, Perrone G, Fornaro L, Ongaro E, Aprile G, Bisonni R, Prisciandaro M, Malkin D, Gariépy J, Fassan M, et al. Mutation Analysis in Gastric Cancer and Clinical Outcomes of Patients with Metastatic Disease Treated with Ramucirumab/Paclitaxel or Standard Chemotherapy. Cancers. 12. PMID 32722340 DOI: 10.3390/Cancers12082049 |
0.4 |
|
| 2020 |
Carbone M, Arron ST, Beutler B, Bononi A, Cavenee W, Cleaver JE, Croce CM, D'Andrea A, Foulkes WD, Gaudino G, Groden JL, Henske EP, Hickson ID, Hwang PM, Kolodner RD, ... ... Malkin D, et al. Tumour predisposition and cancer syndromes as models to study gene-environment interactions. Nature Reviews. Cancer. PMID 32472073 DOI: 10.1038/S41568-020-0265-Y |
0.396 |
|
| 2020 |
Surakhy M, Wallace M, Bond E, Grochola LF, Perez H, Di Giovannantonio M, Zhang P, Malkin D, Carter H, Parise IZS, Zambetti G, Komechen H, Paraizo MM, Pagadala MS, Pinto EM, et al. A common polymorphism in the retinoic acid pathway modifies adrenocortical carcinoma age-dependent incidence. British Journal of Cancer. PMID 32147670 DOI: 10.1038/S41416-020-0764-3 |
0.38 |
|
| 2020 |
McGill BC, Wakefield CE, Hetherington K, Munro LJ, Warby M, Lau L, Tyrrell V, Ziegler DS, O'Brien TA, Marshall GM, Malkin D, Hansford JR, Tucker KM, Vetsch J. "Balancing Expectations with Actual Realities": Conversations with Clinicians and Scientists in the First Year of a High-Risk Childhood Cancer Precision Medicine Trial. Journal of Personalized Medicine. 10. PMID 32075154 DOI: 10.3390/Jpm10010009 |
0.361 |
|
| 2020 |
Malkin D, Light N, Subrasi V, Brew B, Paramathas S, Nabbi A, Prykhozhij S, Pugh T, Berman J, Goldenberg A, Shlien A. Abstract IA02: Novel strategies for early cancer detection and prevention: The Li-Fraumeni syndrome story Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-Ia02 |
0.489 |
|
| 2020 |
Cohen-Gogo S, Langenberg-Ververgaert K, Villani A, Lo W, Young T, Kanwar N, Davidson S, Anderson N, Gallinger B, Layeghifard M, Waldman L, Morgenstern D, Brunga L, Meyn S, Malkin D, et al. Abstract B07: Prospective germline next-generation sequencing in pediatric patients with neuroblastoma identifies frequent alterations in genes involved in DNA damage repair Cancer Research. 80. DOI: 10.1158/1538-7445.Pedca19-B07 |
0.433 |
|
| 2019 |
Suzuki H, Kumar SA, Shuai S, Diaz-Navarro A, Gutierrez-Fernandez A, De Antonellis P, Cavalli FMG, Juraschka K, Farooq H, Shibahara I, Vladoiu MC, Zhang J, Abeysundara N, Przelicki D, Skowron P, ... ... Malkin D, et al. Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma. Nature. 574: 707-711. PMID 31664194 DOI: 10.1038/S41586-019-1650-0 |
0.379 |
|
| 2019 |
Pienkowska M, Choufani S, Turinsky AL, Guha T, Merino DM, Novokmet A, Brudno M, Weksberg R, Shlien A, Hawkins C, Bouffet E, Tabori U, Gilbertson R, Finlay JL, Jabado N, ... ... Malkin D, et al. DNA methylation signature is prognostic of choroid plexus tumor aggressiveness. Clinical Epigenetics. 11: 117. PMID 31409384 DOI: 10.1186/S13148-019-0708-Z |
0.339 |
|
| 2019 |
Salama Y, Albanyan S, Szybowska M, Bullivant G, Gallinger B, Giles RH, Asa S, Badduke C, Chiorean A, Druker H, Ezzat S, Hannah-Shmouni F, Hernandez KG, Inglese C, Jani P, ... ... Malkin D, et al. Comprehensive Characterization of a Canadian Cohort of von Hippel-Lindau Disease Patients. Clinical Genetics. PMID 31368132 DOI: 10.1111/Cge.13613 |
0.322 |
|
| 2019 |
Roberts RD, Lizardo MM, Reed DR, Hingorani P, Glover J, Allen-Rhoades W, Fan T, Khanna C, Sweet-Cordero EA, Cash T, Bishop MW, Hegde M, Sertil AR, Koelsche C, Mirabello L, ... Malkin D, et al. Provocative questions in osteosarcoma basic and translational biology: A report from the Children's Oncology Group. Cancer. PMID 31355930 DOI: 10.1002/Cncr.32351 |
0.385 |
|
| 2019 |
Cullinan N, Villani A, Mourad S, Somers GR, Reichman L, van Engelen K, Stephens D, Weksberg R, Foulkes WD, Malkin D, Grant R, Goudie C. An eHealth Decision-Support Tool to Prioritize Referral Practices for Genetic Evaluation of Patients with Wilms Tumour. International Journal of Cancer. PMID 31286500 DOI: 10.1002/Ijc.32561 |
0.344 |
|
| 2019 |
Negri GL, Grande BM, Delaidelli A, El-Naggar A, Cochrane D, Lau CC, Triche TJ, Moore RA, Jones SJM, Montpetit A, Marra MA, Malkin D, Morin RD, Sorensen PH. Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma. The Journal of Pathology. PMID 31236944 DOI: 10.1002/Path.5319 |
0.438 |
|
| 2019 |
Jivraj I, Somers GR, Belliveau MJ, Malkin D, DeAngelis DD. Management of orbital rhabdomyosarcoma in a child with Li-Fraumeni syndrome. Journal of Aapos : the Official Publication of the American Association For Pediatric Ophthalmology and Strabismus. PMID 30974170 DOI: 10.1016/J.Jaapos.2019.01.013 |
0.311 |
|
| 2019 |
Wang J, Merino DM, Light N, Murphy BL, Wang YD, Guo X, Hodges AP, Chau LQ, Liu KW, Dhall G, Asgharzadeh S, Kiehna EN, Shirey RJ, Janda KD, Taylor MD, ... Malkin D, et al. Myc and loss of p53 cooperate to drive formation of choroid plexus carcinoma. Cancer Research. PMID 30885981 DOI: 10.1158/0008-5472.Can-18-2565 |
0.408 |
|
| 2019 |
Renzi S, Langenberg-Ververgaert K, Fuligni F, Ryan AL, Davidson S, Anderson N, Hayes R, Hopyan S, Gerstle JT, Shago M, Chami R, Malkin D, Shlien A, Villani A, Gupta AA. Aggressive embryonal rhabdomyosarcoma in a 3-month-old boy: A clinical and molecular analysis. Pediatric Hematology and Oncology. 1-8. PMID 30806137 DOI: 10.1080/08880018.2019.1569185 |
0.31 |
|
| 2019 |
Tak CR, Biltaji E, Kohlmann W, Maese L, Hainaut P, Villani A, Malkin D, Sherwin CMT, Brixner DI, Schiffman JD. Cost-effectiveness of early cancer surveillance for patients with Li-Fraumeni syndrome. Pediatric Blood & Cancer. e27629. PMID 30719841 DOI: 10.1002/Pbc.27629 |
0.426 |
|
| 2019 |
Shuen AY, Lanni S, Panigrahi GB, Edwards M, Yu L, Campbell BB, Mandel A, Zhang C, Zhukova N, Alharbi M, Bernstein M, Bowers DC, Carroll S, Cole KA, Constantini S, ... ... Malkin D, et al. Functional Repair Assay for the Diagnosis of Constitutional Mismatch Repair Deficiency From Non-Neoplastic Tissue. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO1800474. PMID 30608896 DOI: 10.1200/Jco.18.00474 |
0.4 |
|
| 2019 |
Michaeli O, Tabori U, Schiffman JD, Naumer A, Kohlmann W, Evans DG, Forde C, Hoffman LM, Rednam SP, Maxwell KN, Bornhorst M, O'Neill AF, Nichols K, Villani A, Slavin TP, ... ... Malkin D, et al. Gliomas in the context of Li-Fraumeni syndrome: An international cohort. Journal of Clinical Oncology. 37: 1517-1517. DOI: 10.1200/Jco.2019.37.15_Suppl.1517 |
0.413 |
|
| 2019 |
Anderson ND, Borja Rd, Young MD, Fuligni F, Rosic A, Roberts ND, Pillay N, Toretsky JA, Akihiko Y, Shibata T, Metzler M, Somers G, Scherer SW, Flanagan AM, Campbell PJ, ... ... Malkin D, et al. Abstract 2506: Exploring the complex etiology of oncogenic fusions in childhood cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2506 |
0.334 |
|
| 2019 |
Giovino C, Patel N, Paramathas S, Zafarana G, Kafri R, Malkin D. Abstract 2032: Investigating the contribution of mTORC1-dependent signaling in the microenvironment to cancer onset in Li-Fraumeni syndrome Cancer Research. 79: 2032-2032. DOI: 10.1158/1538-7445.Am2019-2032 |
0.401 |
|
| 2019 |
Subasri V, Light N, Brew B, Anderson N, Shlien A, Goldenberg A, Malkin D. Abstract 1639: Predictive modeling of cancer-type in Li-Fraumeni syndrome Cancer Research. 79: 1639-1639. DOI: 10.1158/1538-7445.Am2019-1639 |
0.441 |
|
| 2018 |
Bhatt MD, Al-Karmi S, Druker H, Gupta A, Lu M, Malkin D, Somers G, Huang A, Bouffet E. Second rhabdoid tumor 8 years after treatment of atypical teratoid/rhabdoid tumor in a child with germline SMARCB1 mutation. Pediatric Blood & Cancer. e27546. PMID 30393974 DOI: 10.1002/Pbc.27546 |
0.381 |
|
| 2018 |
Weber E, Shuman C, Wasserman JD, Barrera M, Patenaude AF, Fung K, Chitayat D, Malkin D, Druker H. "A change in perspective": Exploring the experiences of adolescents with hereditary tumor predisposition. Pediatric Blood & Cancer. e27445. PMID 30207072 DOI: 10.1002/Pbc.27445 |
0.357 |
|
| 2018 |
Anderson ND, de Borja R, Young MD, Fuligni F, Rosic A, Roberts ND, Hajjar S, Layeghifard M, Novokmet A, Kowalski PE, Anaka M, Davidson S, Zarrei M, Id Said B, Schreiner LC, ... ... Malkin D, et al. Rearrangement bursts generate canonical gene fusions in bone and soft tissue tumors. Science (New York, N.Y.). 361. PMID 30166462 DOI: 10.1126/Science.Aam8419 |
0.363 |
|
| 2018 |
Goudie C, Cullinan N, Villani A, Mathews N, van Engelen K, Malkin D, Irwin MS, Foulkes WD. Retrospective evaluation of a decision-support algorithm (MIPOGG) for genetic referrals for children with neuroblastic tumors. Pediatric Blood & Cancer. e27390. PMID 30117275 DOI: 10.1002/Pbc.27390 |
0.437 |
|
| 2018 |
Prykhozhij SV, Fuller C, Steele SL, Veinotte CJ, Razaghi B, Robitaille JM, McMaster CR, Shlien A, Malkin D, Berman JN. Optimized knock-in of point mutations in zebrafish using CRISPR/Cas9. Nucleic Acids Research. PMID 30053067 DOI: 10.1093/Nar/Gky674 |
0.309 |
|
| 2018 |
Fischer NW, Prodeus A, Tran J, Malkin D, Gariépy J. Association Between the Oligomeric Status of p53 and Clinical Outcomes in Li-Fraumeni Syndrome. Journal of the National Cancer Institute. PMID 29955864 DOI: 10.1093/Jnci/Djy114 |
0.392 |
|
| 2018 |
Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, ... ... Malkin D, et al. Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort. The Lancet. Oncology. PMID 29753700 DOI: 10.1016/S1470-2045(18)30242-0 |
0.354 |
|
| 2018 |
Brown NJ, Bhatia K, Teague J, White SM, Lo P, Challis J, Beshay V, Sullivan M, Malkin D, Hansford JR. Report of a bi-allelic truncating germline mutation in TP53. Familial Cancer. PMID 29737433 DOI: 10.1007/S10689-018-0087-1 |
0.404 |
|
| 2018 |
Hayes MN, McCarthy K, Jin A, Oliveira ML, Iyer S, Garcia SP, Sindiri S, Gryder B, Motala Z, Nielsen GP, Borg JP, van de Rijn M, Malkin D, Khan J, Ignatius MS, et al. Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma. Cell Stem Cell. 22: 414-427.e6. PMID 29499154 DOI: 10.1016/J.Stem.2018.02.002 |
0.319 |
|
| 2018 |
Schultz KAP, Williams GM, Kamihara J, Stewart DR, Harris AK, Bauer AJ, Turner J, Shah R, Schneider K, Schneider KW, Carr AG, Harney LA, Baldinger S, Frazier AL, Orbach D, ... ... Malkin D, et al. DICER1 and associated conditions: Identification of at-risk individuals and recommended surveillance strategies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29343557 DOI: 10.1158/1078-0432.Ccr-17-3089 |
0.404 |
|
| 2018 |
Shaul E, Roth M, Lo Y, Geller DS, Hoang B, Yang R, Malkin D, Gorlick R, Gill J. Pediatric oncologist willingness to offer germline TP53 testing in osteosarcoma. Cancer. PMID 29313943 DOI: 10.1002/Cncr.31212 |
0.457 |
|
| 2018 |
Malkin D. Abstract IA02: Modeling sarcoma susceptibility: The Li-Fraumeni syndrome paradigm Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-Ia02 |
0.462 |
|
| 2018 |
Campbell BB, Light N, Fabrizio D, Bouffet E, Larouche V, Samuel D, Stearns D, Cole KA, Opocher E, Thomas G, Sabel M, Dirks P, Taylor M, Malkin D, Albrecht S, et al. HGG-17. TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE REPLICATION REPAIR DEFICIENCY AND PREDICT RESPONSE TO IMMUNE CHECKPOINT INHIBITION Neuro-Oncology. 20: i92-i92. DOI: 10.1093/Neuonc/Noy059.289 |
0.375 |
|
| 2018 |
Coltin H, Pan A, Malkin D, Huang A, Goudie C. ATRT-13. CANCER PREDISPOSITION AMONG CHILDREN WITH RHABDOID TUMORS: A SINGLE-CENTRE RETROSPECTIVE REVIEW Neuro-Oncology. 20: i30-i30. DOI: 10.1093/Neuonc/Noy059.012 |
0.394 |
|
| 2017 |
Wakefield CE, Quinn VF, Fardell JE, Signorelli C, Tucker KM, Patenaude AF, Malkin D, Walwyn T, Alvaro F, Cohn RJ. Family history-taking practices and genetic confidence in primary and tertiary care providers for childhood cancer survivors. Pediatric Blood & Cancer. PMID 29286558 DOI: 10.1002/Pbc.26923 |
0.344 |
|
| 2017 |
Alexander S, Greenberg M, Malkin D, Portwine C, Johnston D, Silva M, Zelcer S, Sonshine S, Manzo J, Bennett C, Brodeur-Robb K, Deveault C, Ramachandran N, Gibson P. Pediatric oncology clinical trial participation where the geography is vast: Development of a clinical research system for tertiary and satellite centers in Ontario, Canada. Pediatric Blood & Cancer. PMID 29271602 DOI: 10.1002/Pbc.26901 |
0.636 |
|
| 2017 |
Malkin D, Nichols KE, Schiffman JD, Plon SE, Brodeur GM. The Future of Surveillance in the Context of Cancer Predisposition: Through the Murky Looking Glass. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: e133-e137. PMID 29093018 DOI: 10.1158/1078-0432.Ccr-17-2026 |
0.408 |
|
| 2017 |
Campbell BB, Light N, Fabrizio D, Zatzman M, Fuligni F, de Borja R, Davidson S, Edwards M, Elvin JA, Hodel KP, Zahurancik WJ, Suo Z, Lipman T, Wimmer K, Kratz CP, ... ... Malkin D, et al. Comprehensive Analysis of Hypermutation in Human Cancer. Cell. PMID 29056344 DOI: 10.1016/J.Cell.2017.09.048 |
0.445 |
|
| 2017 |
Kratz CP, Achatz MI, Brugières L, Frebourg T, Garber JE, Greer MC, Hansford JR, Janeway KA, Kohlmann WK, McGee R, Mullighan CG, Onel K, Pajtler KW, Pfister SM, Savage SA, ... ... Malkin D, et al. Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: e38-e45. PMID 28572266 DOI: 10.1158/1078-0432.Ccr-17-0408 |
0.476 |
|
| 2017 |
Brodeur GM, Nichols KE, Plon SE, Schiffman JD, Malkin D. Pediatric Cancer Predisposition and Surveillance: An Overview, and a Tribute to Alfred G. Knudson Jr. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 23: e1-e5. PMID 28572261 DOI: 10.1158/1078-0432.Ccr-17-0702 |
0.409 |
|
| 2017 |
Bueno MT, Martínez-Ríos C, la Puente Gregorio A, Ahyad RA, Villani A, Druker H, van Engelen K, Gallinger B, Aronoff L, Grant R, Malkin D, Greer MC. Pediatric imaging in DICER1 syndrome. Pediatric Radiology. PMID 28474256 DOI: 10.1007/S00247-017-3875-0 |
0.339 |
|
| 2017 |
Morrissy AS, Cavalli FM, Remke M, Ramaswamy V, Shih DJ, Holgado BL, Farooq H, Donovan LK, Garzia L, Agnihotri S, Kiehna EN, Mercier E, Mayoh C, Papillon-Cavanagh S, Nikbakht H, ... ... Malkin D, et al. Spatial heterogeneity in medulloblastoma. Nature Genetics. PMID 28394352 DOI: 10.1038/Ng.3838 |
0.36 |
|
| 2017 |
Guha T, Malkin D. Inherited TP53 Mutations and the Li-Fraumeni Syndrome. Cold Spring Harbor Perspectives in Medicine. PMID 28270529 DOI: 10.1101/Cshperspect.A026187 |
0.458 |
|
| 2017 |
Leroy B, Ballinger ML, Baran-Marszak F, Bond GL, Braithwaite A, Concin N, Donehower LA, El-Deiry WS, Fenaux P, Gaidano G, Langerød A, Hellstrom-Lindberg E, Iggo R, Lehmann-Che J, Mai PL, ... Malkin D, et al. Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice. Cancer Research. PMID 28254861 DOI: 10.1158/0008-5472.Can-16-2179 |
0.457 |
|
| 2017 |
Goudie C, Coltin H, Witkowski L, Mourad S, Malkin D, Foulkes WD. The McGill Interactive Pediatric OncoGenetic Guidelines: An approach to identifying pediatric oncology patients most likely to benefit from a genetic evaluation. Pediatric Blood & Cancer. PMID 28097779 DOI: 10.1002/Pbc.26441 |
0.36 |
|
| 2017 |
Brew BM, Malkin D, Erdman L, Doria A, Berman J, Shlien A, Guha T, Novokmet A, Goldenberg A. Abstract 973: Methylation accurately predicts age of cancer onset in patients with Li Fraumeni Syndrome Cancer Research. 77: 973-973. DOI: 10.1158/1538-7445.Am2017-973 |
0.356 |
|
| 2017 |
Erdman L, Brew B, Berman J, Shlien A, Doria A, Malkin D, Goldenberg A. Abstract 3409: Age of cancer onset differentiated by sex and TP53 codon change in Li-Fraumeni Syndrome patient population Cancer Research. 77: 3409-3409. DOI: 10.1158/1538-7445.Am2017-3409 |
0.335 |
|
| 2017 |
Paramathas S, Lewis N, Guha T, Motala Z, Malkin D. Abstract 2741: Assessing the utility of circulating tumor DNA as a surveillance tool for sarcomas and Li-Fraumeni syndrome using a pre-clinical model Cancer Research. 77: 2741-2741. DOI: 10.1158/1538-7445.Am2017-2741 |
0.432 |
|
| 2017 |
Campbell BB, Angelini P, Light N, Bouffet E, Larouche V, Samuel D, Stearns D, Cole KA, Opocher E, Sabel M, George B, Ziegler D, Laperriere N, Meyn S, Malkin D, et al. PDTM-21. LARGE SCALE TUMOR MUTATIONAL BURDEN ANALYSIS OF PEDIATRIC TUMORS PROVIDES A DIAGNOSTIC TOOL FOR GERMLINE PREDISPOSITION AND REVEALS NOVEL CANDIDATES FOR IMMUNE CHECKPOINT INHIBITION Neuro-Oncology. 19: vi194-vi194. DOI: 10.1093/Neuonc/Nox168.785 |
0.375 |
|
| 2016 |
Torchia J, Golbourn B, Feng S, Ho KC, Sin-Chan P, Vasiljevic A, Norman JD, Guilhamon P, Garzia L, Agamez NR, Lu M, Chan TS, Picard D, de Antonellis P, Khuong-Quang DA, ... ... Malkin D, et al. Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors. Cancer Cell. 30: 891-908. PMID 27960086 DOI: 10.1016/J.Ccell.2016.11.003 |
0.359 |
|
| 2016 |
Samuel N, Said BI, Guha T, Novokmet A, Li W, Silwal-Pandit L, Børrsen-Dale AL, Langerød A, Hudson TJ, Malkin D. Assessment of TP53 Polymorphisms and MDM2 SNP309 in Pre-Menopausal Breast Cancer Risk. Human Mutation. PMID 27957778 DOI: 10.1002/Humu.23154 |
0.353 |
|
| 2016 |
Khakban A, Mohammadi T, Lynd LD, Mabbott D, Bouffet E, Gastonguay L, Zafari Z, Malkin D, Taylor M, Marra CA. Societal preferences in the treatment of pediatric medulloblastoma: Balancing risk of death and quality of life. Pediatric Blood & Cancer. PMID 27917595 DOI: 10.1002/Pbc.26340 |
0.319 |
|
| 2016 |
Fischer NW, Prodeus A, Malkin D, Gariépy J. p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosis. Cell Cycle (Georgetown, Tex.). 0. PMID 27754743 DOI: 10.1080/15384101.2016.1241917 |
0.353 |
|
| 2016 |
Alabbas F, Weitzman S, Grant R, Bouffet E, Malkin D, Abla O, Dror Y. Underlying undiagnosed inherited marrow failure syndromes among children with cancer. Pediatric Blood & Cancer. PMID 27577695 DOI: 10.1002/Pbc.26120 |
0.39 |
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| 2016 |
Samuel N, Wilson G, Lemire M, Id Said B, Lou Y, Li W, Merino D, Novokmet A, Tran J, Nichols KE, Finlay JL, Choufani S, Remke M, Ramaswamy V, Cavalli FM, ... ... Malkin D, et al. Genome-Wide DNA Methylation Analysis Reveals Epigenetic Dysregulation of MicroRNA-34A in TP53-Associated Cancer Susceptibility. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27551116 DOI: 10.1200/Jco.2016.67.6940 |
0.427 |
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| 2016 |
Villani A, Shore A, Wasserman JD, Stephens D, Kim RH, Druker H, Gallinger B, Naumer A, Kohlmann W, Novokmet A, Tabori U, Tijerin M, Greer MC, Finlay JL, Schiffman JD, ... Malkin D, et al. Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study. The Lancet. Oncology. PMID 27501770 DOI: 10.1016/S1470-2045(16)30249-2 |
0.383 |
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| 2016 |
Said BI, Kim H, Tran J, Novokmet A, Malkin D. Super-transactivation TP53 Variant in the Germline of a Family with Li-Fraumeni Syndrome. Human Mutation. PMID 27297285 DOI: 10.1002/Humu.23025 |
0.432 |
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| 2016 |
Malkin D, Garber JE, Strong LC, Friend SH. CANCER. The cancer predisposition revolution. Science (New York, N.Y.). 352: 1052-3. PMID 27230363 DOI: 10.1126/Science.Aag0832 |
0.475 |
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| 2016 |
Oh S, Flynn RA, Floor SN, Purzner J, Martin L, Do BT, Schubert S, Vaka D, Morrissy S, Li Y, Kool M, Hovestadt V, Jones DT, Northcott PA, Risch T, ... ... Malkin D, et al. Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress. Oncotarget. 7: 28169-82. PMID 27058758 DOI: 10.18632/Oncotarget.8612 |
0.303 |
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| 2016 |
Bouffet E, Larouche V, Campbell BB, Merico D, de Borja R, Aronson M, Durno C, Krueger J, Cabric V, Ramaswamy V, Zhukova N, Mason G, Farah R, Afzal S, Yalon M, ... ... Malkin D, et al. Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 27001570 DOI: 10.1200/Jco.2016.66.6552 |
0.363 |
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| 2016 |
Ernst A, Jones DT, Maass KK, Rode A, Deeg KI, Michael Chelliah Jebaraj B, Korshunov A, Hovestadt V, Tainsky MA, Pajtler KW, Bender S, Brabetz S, Gröbner S, Kool M, Devens F, ... ... Malkin D, et al. Telomere dysfunction and chromothripsis. International Journal of Cancer. Journal International Du Cancer. PMID 26856307 DOI: 10.1002/Ijc.30033 |
0.343 |
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| 2016 |
Malkin D. Li-Fraumeni Syndrome and p53 in 2015: Celebrating their Silver Anniversary. Clinical and Investigative Medicine. MéDecine Clinique Et Experimentale. 39: E37-47. PMID 26833171 DOI: 10.25011/Cim.V39I1.26328 |
0.462 |
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| 2016 |
Morrissy AS, Garzia L, Shih DJ, Zuyderduyn S, Huang X, Skowron P, Remke M, Cavalli FM, Ramaswamy V, Lindsay PE, Jelveh S, Donovan LK, Wang X, Luu B, Zayne K, ... ... Malkin D, et al. Divergent clonal selection dominates medulloblastoma at recurrence. Nature. PMID 26760213 DOI: 10.1038/Nature16478 |
0.325 |
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| 2016 |
Shlien A, Malkin D, Tabori U. Translational Childhood Cancer Genomics: The Future Is Now. Jama Oncology. 2: 384-5. PMID 26747469 DOI: 10.1001/Jamaoncol.2015.5076 |
0.435 |
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| 2016 |
Aronson M, Gallinger S, Cohen Z, Cohen S, Dvir R, Elhasid R, Baris HN, Kariv R, Druker H, Chan H, Ling SC, Kortan P, Holter S, Semotiuk K, Malkin D, et al. Gastrointestinal Findings in the Largest Series of Patients With Hereditary Biallelic Mismatch Repair Deficiency Syndrome: Report from the International Consortium. The American Journal of Gastroenterology. PMID 26729549 DOI: 10.1038/Ajg.2015.392 |
0.379 |
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| 2016 |
Said BI, Kim H, Tran J, Novokmet A, Malkin D. Abstract 792: Super-transactivation TP53 variant in the germline of a family with Li-Fraumeni variant Cancer Research. 76: 792-792. DOI: 10.1158/1538-7445.Am2016-792 |
0.409 |
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| 2016 |
Pienkowska M, Choufani S, Turinsky A, Merino D, Novokmet A, Brudno M, Weksberg R, Shlien A, Hawkins C, Bouffet E, Tabori U, Gilbertson R, Malkin D. Abstract 2789: Investigating the role of DNA methylation in pediatric choroid plexus tumors Cancer Research. 76: 2789-2789. DOI: 10.1158/1538-7445.Am2016-2789 |
0.387 |
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| 2016 |
Campbell B, Bouffet E, Larouche V, Mason G, Reddy A, Osborne M, Magimairajan V, Merico D, Borja Rd, Chung B, Galati M, Aronson M, Durno C, Krueger J, Cabric V, ... ... Malkin D, et al. PDCT-09. HYPERMUTATION AND NEOANTIGEN FORMATION IS DIAGNOSTIC AND PREDICT RESPONSE TO IMMUNE CHECKPOINT INHIBITION IN CHILDHOOD BIALLELIC MISMATCH REPAIR DEFICIENT BRAIN TUMORS Neuro-Oncology. 18: vi147-vi147. DOI: 10.1093/Neuonc/Now212.613 |
0.301 |
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| 2016 |
Durno C, Aronson M, Campbell B, Zhukova N, Shlien A, Reddy AT, Hawkins C, Malkin D, Bouffet E, Mason G, Hansford J, Peterson L, Osborn M, Sullivan M, Taylor M, et al. Sa2045 Tumor Spectrum, Diagnostic Tools and Survival in Patients With Biallelic Mismatch Repair Gene Deficiency (BMMRD) Syndrome: Report From the International BMMRD Consortium Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)31522-0 |
0.382 |
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| 2015 |
Amayiri N, Tabori U, Campbell B, Bakry D, Aronson M, Durno C, Rakopoulos P, Malkin D, Qaddoumi I, Musharbash A, Swaidan M, Bouffet E, Hawkins C, Al-Hussaini M. High frequency of mismatch repair deficiency among pediatric high grade gliomas in Jordan. International Journal of Cancer. Journal International Du Cancer. PMID 26293621 DOI: 10.1002/Ijc.29724 |
0.477 |
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| 2015 |
Elhasid R, Dvir R, Rosenfeld Keidar H, Ben Shachar S, Bitan M, Solar I, Durno C, Aronson M, Malkin D, Hawkins C, Bouffet E, Tabori U. Management of Acute Myeloblastic Leukemia in a Child With Biallelic Mismatch Repair Deficiency. Journal of Pediatric Hematology/Oncology. 37: e490-3. PMID 26274037 DOI: 10.1097/Mph.0000000000000415 |
0.376 |
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| 2015 |
Nichols KE, Malkin D. Genotype Versus Phenotype: The Yin and Yang of Germline TP53 Mutations in Li Fraumeni Syndrome. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26101242 DOI: 10.1200/Jco.2015.61.5757 |
0.491 |
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| 2015 |
Tong Y, Merino D, Nimmervoll B, Gupta K, Wang YD, Finkelstein D, Dalton J, Ellison DW, Ma X, Zhang J, Malkin D, Gilbertson RJ. Cross-Species Genomics Identifies TAF12, NFYC, and RAD54L as Choroid Plexus Carcinoma Oncogenes. Cancer Cell. 27: 712-27. PMID 25965574 DOI: 10.1016/J.Ccell.2015.04.005 |
0.341 |
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| 2015 |
Durno CA, Sherman PM, Aronson M, Malkin D, Hawkins C, Bakry D, Bouffet E, Gallinger S, Pollett A, Campbell B, Tabori U. Phenotypic and genotypic characterisation of biallelic mismatch repair deficiency (BMMR-D) syndrome. European Journal of Cancer (Oxford, England : 1990). 51: 977-83. PMID 25883011 DOI: 10.1016/J.Ejca.2015.02.008 |
0.4 |
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| 2015 |
de Kock L, Druker H, Weber E, Hamel N, Traubici J, Malkin D, Arseneau J, Stewart CJ, Bouron-Dal Soglio D, Priest JR, Foulkes WD. Ovarian embryonal rhabdomyosarcoma is a rare manifestation of the DICER1 syndrome. Human Pathology. 46: 917-22. PMID 25836323 DOI: 10.1016/J.Humpath.2015.02.008 |
0.415 |
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| 2015 |
Lupo PJ, Danysh HE, Plon SE, Curtin K, Malkin D, Hettmer S, Hawkins DS, Skapek SX, Spector LG, Papworth K, Melin B, Erhardt EB, Grufferman S, Schiffman JD. Family history of cancer and childhood rhabdomyosarcoma: a report from the Children's Oncology Group and the Utah Population Database. Cancer Medicine. 4: 781-90. PMID 25809884 DOI: 10.1002/Cam4.448 |
0.362 |
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| 2015 |
Id Said B, Malkin D. A functional variant in miR-605 modifies the age of onset in Li-Fraumeni syndrome. Cancer Genetics. 208: 47-51. PMID 25683625 DOI: 10.1016/J.Cancergen.2014.12.003 |
0.363 |
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| 2015 |
Mistry M, Zhukova N, Merico D, Rakopoulos P, Krishnatry R, Shago M, Stavropoulos J, Alon N, Pole JD, Ray PN, Navickiene V, Mangerel J, Remke M, Buczkowicz P, Ramaswamy V, ... ... Malkin D, et al. BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 1015-22. PMID 25667294 DOI: 10.1200/Jco.2014.58.3922 |
0.335 |
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| 2015 |
Shlien A, Campbell BB, de Borja R, Alexandrov LB, Merico D, Wedge D, Van Loo P, Tarpey PS, Coupland P, Behjati S, Pollett A, Lipman T, Heidari A, Deshmukh S, Avitzur N, ... ... Malkin D, et al. Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers. Nature Genetics. 47: 257-62. PMID 25642631 DOI: 10.1038/Ng.3202 |
0.435 |
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| 2015 |
Wasserman JD, Novokmet A, Eichler-Jonsson C, Ribeiro RC, Rodriguez-Galindo C, Zambetti GP, Malkin D. Prevalence and functional consequence of TP53 mutations in pediatric adrenocortical carcinoma: a children's oncology group study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 33: 602-9. PMID 25584008 DOI: 10.1200/Jco.2013.52.6863 |
0.375 |
|
| 2015 |
Merino DM, Shlien A, Villani A, Pienkowska M, Mack S, Ramaswamy V, Shih D, Tatevossian R, Novokmet A, Choufani S, Dvir R, Ben-Arush M, Harris BT, Hwang EI, Lulla R, ... ... Malkin D, et al. Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 184-92. PMID 25336695 DOI: 10.1158/1078-0432.Ccr-14-1324 |
0.369 |
|
| 2015 |
Alderfer MA, Zelley K, Lindell RB, Novokmet A, Mai PL, Garber JE, Nathan D, Scollon S, Chun NM, Patenaude AF, Ford JM, Plon SE, Schiffman JD, Diller LR, Savage SA, ... Malkin D, et al. Parent decision-making around the genetic testing of children for germline TP53 mutations. Cancer. 121: 286-93. PMID 25223899 DOI: 10.1002/Cncr.29027 |
0.363 |
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| 2015 |
Villani A, Shore A, Wasserman J, Druker H, Gallinger B, Novokmet A, Tabori U, Finlay JL, Schiffman JD, Malkin D. Biochemical and imaging surveillance for Li-Fraumeni syndrome: The “Toronto Protocol” at 11 years. Journal of Clinical Oncology. 33: e12546-e12546. DOI: 10.1200/Jco.2015.33.15_Suppl.E12546 |
0.367 |
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| 2015 |
Paixao D, Guimaraes MD, Nobrega AF, Malkin D, Chojniak R, Achatz MIW. Evaluation of rapid whole-body magnetic resonance as screening strategy for early cancer detection in 57 Brazilian Li-Fraumeni syndrome patients. Journal of Clinical Oncology. 33: 1534-1534. DOI: 10.1200/Jco.2015.33.15_Suppl.1534 |
0.439 |
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| 2015 |
Malkin D, Villani A, Wasserman J. Abstract CN10-01: Tumor surveillance strategies in pediatric hereditary cancer predisposition syndromes Cancer Prevention Research. 8. DOI: 10.1158/1940-6215.Prev-14-Cn10-01 |
0.458 |
|
| 2015 |
Shlien A, Campbell BB, Borja Rd, Alexandrov LB, Merico D, Wedge D, Loo PV, Tarpey PS, Coupland P, Pollett A, Lipman T, Heidari A, Deshmukh S, Gerstung M, Merino D, ... ... Malkin D, et al. Abstract B09: DNA polymerase mutations trigger rapid onset of ultra-hypermutant malignant brain tumors in children with biallelic mismatch repair deficiency Brain. 75. DOI: 10.1158/1538-7445.Brain15-B09 |
0.454 |
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| 2015 |
Samuel N, Lemire M, Novokmet A, Hudson TJ, Malkin D. Abstract 4664: Impact of TP53 mutations, single nucleotide variants and global methylation patterns on pre-menopausal breast cancer risk Cancer Research. 75: 4664-4664. DOI: 10.1158/1538-7445.Am2015-4664 |
0.42 |
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| 2015 |
Merino DM, Li Y, Ma X, Zhang J, Malkin D, Gilbertson RJ. Abstract 3280: Sequencing approaches define the mutation and fusion landscape of choroid plexus carcinomas Cancer Research. 75: 3280-3280. DOI: 10.1158/1538-7445.Am2015-3280 |
0.435 |
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| 2015 |
Garzia L, Kijima N, Morrissy A, Donovan L, Wu X, Luu B, Ramaswamy V, Peacock J, Lopez-Holgado B, Wang X, Cavalli F, Rolider A, Shih D, Skowron P, Lee J, ... ... Malkin D, et al. PTPS-08HEMATOGENOUS DISSEMINATION OF MEDULLOBLASTOMA METASTASES TO THE LEPTOMENINGES Neuro-Oncology. 17: v180.4-v180. DOI: 10.1093/Neuonc/Nov228.08 |
0.363 |
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| 2015 |
Moxon-Emre I, Taylor MD, Bouffet E, Hardy K, Campen C, Malkin D, Hawkins C, Laperriere N, Ramaswamy V, Scantlebury N, Spiegler B, Janzen L, Law NM, Walsh KS, Mabbott DJ. NCO-10INTELLECTUAL OUTCOME IN MOLECULAR SUBGROUPS OF MEDULLOBLASTOMA Neuro-Oncology. 17: v148.1-v148. DOI: 10.1093/Neuonc/Nov223.10 |
0.328 |
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| 2015 |
Shlien A, Campbell BB, de Borja R, Alexandrov LB, Merino DM, Remke M, Bakry D, Dirks P, Huang A, Grundy RG, Durno C, Aronson M, Taylor MD, Pursell ZF, Pearson CE, ... Malkin D, et al. GE-09 * COMBINED HEREDITARY AND SOMATIC MUTATIONS OF REPLICATION ERROR REPAIR GENES RESULT IN RAPID ONSET OF ULTRA-HYPERMUTATED MALIGNANT BRAIN TUMORS IN CHILDREN Neuro-Oncology. 17: iii9-iii9. DOI: 10.1093/Neuonc/Nov061.33 |
0.457 |
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| 2015 |
Durno C, Aronson M, Tabori U, Gallinger S, Cohen S, Dvir R, Elhasid R, Feldman HB, Druker H, Chan H, Ling S, Kortan PP, Holter S, Semotiuk K, Malkin D, et al. 548 Gastrointestinal (GI) Findings in Patients With Biallelic Mismatch Repair (BMMRD) Gene Deficiency Syndrome: Report From the International Consortium Gastroenterology. 148: S-110-S-111. DOI: 10.1016/S0016-5085(15)30380-2 |
0.318 |
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| 2014 |
Zhukova N, Ramaswamy V, Remke M, Martin DC, Castelo-Branco P, Zhang CH, Fraser M, Tse K, Poon R, Shih DJ, Baskin B, Ray PN, Bouffet E, Dirks P, von Bueren AO, ... ... Malkin D, et al. WNT activation by lithium abrogates TP53 mutation associated radiation resistance in medulloblastoma. Acta Neuropathologica Communications. 2: 174. PMID 25539912 DOI: 10.1186/S40478-014-0174-Y |
0.378 |
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| 2014 |
Mangerel J, Price A, Castelo-Branco P, Brzezinski J, Buczkowicz P, Rakopoulos P, Merino D, Baskin B, Wasserman J, Mistry M, Barszczyk M, Picard D, Mack S, Remke M, Starkman H, ... ... Malkin D, et al. Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors. Acta Neuropathologica. 128: 853-62. PMID 25315281 DOI: 10.1007/S00401-014-1348-1 |
0.44 |
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| 2014 |
Samuel N, Villani A, Fernandez CV, Malkin D. Management of familial cancer: sequencing, surveillance and society. Nature Reviews. Clinical Oncology. 11: 723-31. PMID 25311347 DOI: 10.1038/Nrclinonc.2014.169 |
0.404 |
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| 2014 |
Merino D, Malkin D. p53 and hereditary cancer. Sub-Cellular Biochemistry. 85: 1-16. PMID 25201186 DOI: 10.1007/978-94-017-9211-0_1 |
0.484 |
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| 2014 |
de Kock L, Sabbaghian N, Druker H, Weber E, Hamel N, Miller S, Choong CS, Gottardo NG, Kees UR, Rednam SP, van Hest LP, Jongmans MC, Jhangiani S, Lupski JR, Zacharin M, ... ... Malkin D, et al. Germ-line and somatic DICER1 mutations in pineoblastoma. Acta Neuropathologica. 128: 583-95. PMID 25022261 DOI: 10.1007/S00401-014-1318-7 |
0.336 |
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| 2014 |
Vanner RJ, Remke M, Gallo M, Selvadurai HJ, Coutinho F, Lee L, Kushida M, Head R, Morrissy S, Zhu X, Aviv T, Voisin V, Clarke ID, Li Y, Mungall AJ, ... ... Malkin D, et al. Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma. Cancer Cell. 26: 33-47. PMID 24954133 DOI: 10.1016/J.Ccr.2014.05.005 |
0.37 |
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| 2014 |
Malkin D, Nichols KE, Zelley K, Schiffman JD. Predisposition to pediatric and hematologic cancers: a moving target. American Society of Clinical Oncology Educational Book / Asco. American Society of Clinical Oncology. Meeting. e44-55. PMID 24857136 DOI: 10.14694/EdBook_AM.2014.34.e44 |
0.332 |
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| 2014 |
Samuel N, Remke M, Rutka JT, Raught B, Malkin D. Proteomic analyses of CSF aimed at biomarker development for pediatric brain tumors. Journal of Neuro-Oncology. 118: 225-38. PMID 24771250 DOI: 10.1007/S11060-014-1432-3 |
0.359 |
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| 2014 |
Malkin D. Surveillance for children at genetic risk for cancer: are we ready? Pediatric Blood & Cancer. 61: 1337-8. PMID 24729514 DOI: 10.1002/Pbc.25061 |
0.344 |
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| 2014 |
Mack SC, Witt H, Piro RM, Gu L, Zuyderduyn S, Stütz AM, Wang X, Gallo M, Garzia L, Zayne K, Zhang X, Ramaswamy V, Jäger N, Jones DT, Sill M, ... ... Malkin D, et al. Epigenomic alterations define lethal CIMP-positive ependymomas of infancy. Nature. 506: 445-50. PMID 24553142 DOI: 10.1038/Nature13108 |
0.343 |
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| 2014 |
Shih DJ, Northcott PA, Remke M, Korshunov A, Ramaswamy V, Kool M, Luu B, Yao Y, Wang X, Dubuc AM, Garzia L, Peacock J, Mack SC, Wu X, Rolider A, ... ... Malkin D, et al. Cytogenetic prognostication within medulloblastoma subgroups. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 886-96. PMID 24493713 DOI: 10.1200/Jco.2013.50.9539 |
0.313 |
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| 2014 |
Bakry D, Aronson M, Durno C, Rimawi H, Farah R, Alharbi QK, Alharbi M, Shamvil A, Ben-Shachar S, Mistry M, Constantini S, Dvir R, Qaddoumi I, Gallinger S, Lerner-Ellis J, ... ... Malkin D, et al. Genetic and clinical determinants of constitutional mismatch repair deficiency syndrome: report from the constitutional mismatch repair deficiency consortium. European Journal of Cancer (Oxford, England : 1990). 50: 987-96. PMID 24440087 DOI: 10.1016/J.Ejca.2013.12.005 |
0.42 |
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| 2014 |
Hettmer S, Archer NM, Somers GR, Novokmet A, Wagers AJ, Diller L, Rodriguez-Galindo C, Teot LA, Malkin D. Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers. Cancer. 120: 1068-75. PMID 24382691 DOI: 10.1002/Cncr.28507 |
0.347 |
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| 2014 |
Morgenstern DA, Soh SY, Stavropoulos DJ, Bowdin S, Baruchel S, Malkin D, Meyn MS, Irwin MS. Metachronous neuroblastoma in an infant with germline translocation resulting in partial trisomy 2p: a role for ALK? Journal of Pediatric Hematology/Oncology. 36: e193-6. PMID 24276038 DOI: 10.1097/Mph.0B013E3182A8F25D |
0.329 |
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| 2014 |
Ju YS, Alexandrov LB, Gerstung M, Martincorena I, Nik-Zainal S, Ramakrishna M, Davies HR, Papaemmanuil E, Gundem G, Shlien A, Bolli N, Behjati S, Tarpey PS, Nangalia J, Massie CE, ... ... Malkin D, et al. Author response: Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer Elife. DOI: 10.7554/Elife.02935.028 |
0.335 |
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| 2014 |
castelo-branco P, Choufani S, Mack S, Gallagher D, Zhang C, Lipman T, Zhukova N, Walker EJ, Merino D, Jonathan JD, Elizabeth C, Alon N, Zhang L, Hovestadt V, Kool M, ... ... Malkin D, et al. Abstract A20: hTERT promoter hypermethylation is a cancer signature which predicts survival and response to targeted therapy in pediatric nervous system tumors Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-A20 |
0.41 |
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| 2014 |
Wasserman J, Villani A, Samuel N, Merino D, Novokmet A, Pienkowska M, IdSaid B, Malkin D. Abstract IA10: Li-Fraumeni syndrome: p53 and beyond Cancer Research. 74. DOI: 10.1158/1538-7445.Cansusc14-Ia10 |
0.474 |
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| 2014 |
Bakry D, Campbell B, Durno C, Aronson M, Alharbi Q, Alharbi M, Constantini S, Pollett A, Ben-Shachar S, Lerner-Ellis J, Gallinger S, Elhasid R, Farah R, Qaddoumi I, Mistry M, ... ... Malkin D, et al. Abstract 35: Novel genetic and clinical determinants of Constitutional Mismatch Repair Deficiency syndrome: Report from the CMMRD consortium Cancer Research. 74: 35-35. DOI: 10.1158/1538-7445.Cansusc14-35 |
0.508 |
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| 2014 |
Villani A, Novokmet A, Malkin D. Abstract 34: Investigating PIN1 as a genetic modifier in Li-Fraumeni syndrome Cancer Research. 74: 34-34. DOI: 10.1158/1538-7445.Cansusc14-34 |
0.459 |
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| 2014 |
Samuel N, Novokmet A, Hudson TJ, Malkin D. Abstract 16: Impact of germline TP53 mutations and polymorphisms in women with premenopausal breast cancer Cancer Research. 74: 16-16. DOI: 10.1158/1538-7445.Cansusc14-16 |
0.395 |
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| 2014 |
Lupo PJ, Danysh HE, Plon SE, Malkin D, Hettmer S, Hawkins DS, Skapek SX, Spector LG, Papworth K, Melin B, Erhardt EB, Grufferman S. Abstract 1296: Family history of cancer and rhabdomyosarcoma in children: a report from the Children's Oncology Group Cancer Research. 74: 1296-1296. DOI: 10.1158/1538-7445.Am2014-1296 |
0.316 |
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| 2014 |
Mistry M, Zhukova N, Merico D, Rakopoulos P, Krishnatry R, Shago M, Stavropoulos J, Pole J, Ray P, Remke M, Buczkowicz P, Ramaswamy V, Shlien A, Rutka J, Dirks P, ... ... Malkin D, et al. Bi-21Braf Mutation And Cdkn2A Deletions Define A Clinically Distinct Subgroup Of Childhood Secondary High Grade Glioma Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov061.70 |
0.428 |
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| 2014 |
Morrissy S, Garzia L, Remke M, Ramaswamy V, Jorgensen F, Wu X, Shah S, Ma Y, Mungall K, Meter TV, Cho Y, Collins P, MacDonald T, Li X, Moore R, ... ... Malkin D, et al. Ge-21Drastic Genomic Divergence Of Recurrent Medulloblastoma Invalidates Targeted Therapies Discovered At Diagnosis. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou256.20 |
0.381 |
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| 2013 |
Zhukova N, Ramaswamy V, Remke M, Pfaff E, Shih DJ, Martin DC, Castelo-Branco P, Baskin B, Ray PN, Bouffet E, von Bueren AO, Jones DT, Northcott PA, Kool M, Sturm D, ... ... Malkin D, et al. Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2927-35. PMID 23835706 DOI: 10.1200/Jco.2012.48.5052 |
0.425 |
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| 2013 |
Cheung YH, Gayden T, Campeau PM, LeDuc CA, Russo D, Nguyen VH, Guo J, Qi M, Guan Y, Albrecht S, Moroz B, Eldin KW, Lu JT, Schwartzentruber J, Malkin D, et al. A recurrent PDGFRB mutation causes familial infantile myofibromatosis. American Journal of Human Genetics. 92: 996-1000. PMID 23731537 DOI: 10.1016/J.Ajhg.2013.04.026 |
0.387 |
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| 2013 |
Testa JR, Malkin D, Schiffman JD. Connecting molecular pathways to hereditary cancer risk syndromes. American Society of Clinical Oncology Educational Book / Asco. American Society of Clinical Oncology. Meeting. 81-90. PMID 23714463 DOI: 10.1200/EdBook_AM.2013.33.81 |
0.376 |
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| 2013 |
Felgenhauer JL, Nieder ML, Krailo MD, Bernstein ML, Henry DW, Malkin D, Baruchel S, Chuba PJ, Sailer SL, Brown K, Ranganathan S, Marina N. A pilot study of low-dose anti-angiogenic chemotherapy in combination with standard multiagent chemotherapy for patients with newly diagnosed metastatic Ewing sarcoma family of tumors: A Children's Oncology Group (COG) Phase II study NCT00061893. Pediatric Blood & Cancer. 60: 409-14. PMID 23065953 DOI: 10.1002/Pbc.24328 |
0.311 |
|
| 2013 |
Fernandez CV, Jabado N, Boycott K, Malkin D, Bouffet E, O'Connell C, Avard D, Knoppers B, Sorensen P, Orr AC, McMaster C. Attitudes to the return of incidental and targeted genomic findings obtained in a high-risk pediatric cancer versus an inherited genetic condition research setting Journal of Clinical Oncology. 31: 10066-10066. DOI: 10.1200/Jco.2013.31.15_Suppl.10066 |
0.319 |
|
| 2013 |
Pienkowska M, Choufani S, Lach B, Merino DM, Novokmet A, Tabori U, Gilbertson R, Malkin D. Abstract 661: Identification of epigenomic markers on chromosome 11 that distinguish between choroid plexus carcinoma (CPC) and papilloma (CPP). Cancer Research. 73: 661-661. DOI: 10.1158/1538-7445.Am2013-661 |
0.384 |
|
| 2013 |
Motala ZA, Chen K, Malkin D. Abstract 5029: The role of estrogen receptor signaling in rhabdomyosarcoma. Cancer Research. 73: 5029-5029. DOI: 10.1158/1538-7445.Am2013-5029 |
0.364 |
|
| 2013 |
Idsaid B, Malkin D. Abstract 3063: MicroRNA-605: A novel genetic modifier in Li-Fraumeni Syndrome. Cancer Research. 73: 3063-3063. DOI: 10.1158/1538-7445.Am2013-3063 |
0.355 |
|
| 2012 |
Mai PL, Malkin D, Garber JE, Schiffman JD, Weitzel JN, Strong LC, Wyss O, Locke L, Means V, Achatz MI, Hainaut P, Frebourg T, Evans DG, Bleiker E, Patenaude A, et al. Li-Fraumeni syndrome: report of a clinical research workshop and creation of a research consortium. Cancer Genetics. 205: 479-87. PMID 22939227 DOI: 10.1016/J.Cancergen.2012.06.008 |
0.381 |
|
| 2012 |
McCuaig JM, Armel SR, Novokmet A, Ginsburg OM, Demsky R, Narod SA, Malkin D. Routine TP53 testing for breast cancer under age 30: ready for prime time? Familial Cancer. 11: 607-13. PMID 22851211 DOI: 10.1007/S10689-012-9557-Z |
0.369 |
|
| 2012 |
Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, ... ... Malkin D, et al. Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature. 488: 49-56. PMID 22832581 DOI: 10.1038/Nature11327 |
0.307 |
|
| 2012 |
Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DA, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, ... ... Malkin D, et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature. 482: 226-31. PMID 22286061 DOI: 10.1038/Nature10833 |
0.364 |
|
| 2012 |
Rausch T, Jones DT, Zapatka M, Stütz AM, Zichner T, Weischenfeldt J, Jäger N, Remke M, Shih D, Northcott PA, Pfaff E, Tica J, Wang Q, Massimi L, Witt H, ... ... Malkin D, et al. Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell. 148: 59-71. PMID 22265402 DOI: 10.1016/J.Cell.2011.12.013 |
0.447 |
|
| 2012 |
Villani A, Malkin D, Tabori U. Syndromes predisposing to pediatric central nervous system tumors: lessons learned and new promises. Current Neurology and Neuroscience Reports. 12: 153-64. PMID 22205236 DOI: 10.1007/S11910-011-0244-5 |
0.458 |
|
| 2012 |
Durno CA, Aronson M, Tabori U, Malkin D, Gallinger S, Chan HS. Oncologic surveillance for subjects with biallelic mismatch repair gene mutations: 10 year follow-up of a kindred. Pediatric Blood & Cancer. 59: 652-6. PMID 22180144 DOI: 10.1002/Pbc.24019 |
0.473 |
|
| 2012 |
Walker EJ, Zhang C, Castelo-Branco P, Hawkins C, Wilson W, Zhukova N, Alon N, Novokmet A, Baskin B, Ray P, Knobbe C, Dirks P, Taylor MD, Croul S, Malkin D, et al. Monoallelic expression determines oncogenic progression and outcome in benign and malignant brain tumors. Cancer Research. 72: 636-44. PMID 22144470 DOI: 10.1158/0008-5472.Can-11-2266 |
0.417 |
|
| 2012 |
Gozali AE, Britt B, Shane L, Gonzalez I, Gilles F, McComb JG, Krieger MD, Lavey RS, Shlien A, Villablanca JG, Erdreich-Epstein A, Dhall G, Jubran R, Tabori U, Malkin D, et al. Choroid plexus tumors; management, outcome, and association with the Li-Fraumeni syndrome: the Children's Hospital Los Angeles (CHLA) experience, 1991-2010. Pediatric Blood & Cancer. 58: 905-9. PMID 21990040 DOI: 10.1002/Pbc.23349 |
0.364 |
|
| 2012 |
Wasserman JD, Zambetti GP, Malkin D. Towards an understanding of the role of p53 in adrenocortical carcinogenesis. Molecular and Cellular Endocrinology. 351: 101-10. PMID 21930187 DOI: 10.1016/J.Mce.2011.09.010 |
0.418 |
|
| 2012 |
Musselman J, Bergemann T, Krailo M, Malkin D, Ross J, Savage S, Nagarajan R, Sklar C, Spector L. Abstract LB-333: A case-parent-triad approach in assessing risk of osteosarcoma associated with genetic variation in insulin-like growth factor 1/growth hormone axis genes: a Children's Oncology Group (COG) study Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-333 |
0.351 |
|
| 2012 |
Zhukova N, Martin D, Lipman T, Castelo-Branco P, Zhang CH, Fraser M, Baskin B, Ray P, Bouffet E, Bristow R, Alman BA, Taylor MD, Malkin D, Hawkins C, Tabori U. Abstract LB-210: Abrogation of mutant TP53 radiation resistance by lithium induced CTNNB1 (β-catenin) activation in medulloblastoma. Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-210 |
0.358 |
|
| 2012 |
Merino DM, Shlien A, Pienkowska M, Tabori U, Gilbertson RJ, Malkin D. Abstract 2479: TP53 status as a marker of recurrence and survival in choroid plexus carcinomas Cancer Research. 72: 2479-2479. DOI: 10.1158/1538-7445.Am2012-2479 |
0.459 |
|
| 2012 |
Porat RM, Pasic I, Shlien A, Gokgoz N, Andrulis I, Wunder JS, Malkin D. Abstract 1447: Investigating susceptibility to sporadic osteosarcoma by genome-wide copy number analysis Cancer Research. 72: 1447-1447. DOI: 10.1158/1538-7445.Am2012-1447 |
0.72 |
|
| 2012 |
Bakry D, Novokmet A, Malkin D. Abstract 1435: Phenotype:Genotype correlations of p53 mutation carriers: The 20-year Toronto experience Cancer Research. 72: 1435-1435. DOI: 10.1158/1538-7445.Am2012-1435 |
0.487 |
|
| 2011 |
Nam RK, Zhang W, Siminovitch K, Shlien A, Kattan MW, Klotz LH, Trachtenberg J, Lu Y, Zhang J, Yu C, Toi A, Loblaw DA, Venkateswaran V, Stanimirovic A, Sugar L, ... Malkin D, et al. New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort. Cancer Biology & Therapy. 12: 997-1004. PMID 22130093 DOI: 10.4161/Cbt.12.11.18366 |
0.308 |
|
| 2011 |
Ibrahim GM, Huang A, Halliday W, Dirks PB, Malkin D, Baskin B, Shago M, Hawkins C. Cribriform neuroepithelial tumour: novel clinicopathological, ultrastructural and cytogenetic findings. Acta Neuropathologica. 122: 511-4. PMID 21918902 DOI: 10.1007/S00401-011-0872-5 |
0.345 |
|
| 2011 |
Malkin D. Li-fraumeni syndrome. Genes & Cancer. 2: 475-84. PMID 21779515 DOI: 10.1177/1947601911413466 |
0.465 |
|
| 2011 |
Villani A, Tabori U, Schiffman J, Shlien A, Beyene J, Druker H, Novokmet A, Finlay J, Malkin D. Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study. The Lancet. Oncology. 12: 559-67. PMID 21601526 DOI: 10.1016/S1470-2045(11)70119-X |
0.38 |
|
| 2011 |
Castelo-Branco P, Zhang C, Lipman T, Fujitani M, Hansford L, Clarke I, Harley CB, Tressler R, Malkin D, Walker E, Kaplan DR, Dirks P, Tabori U. Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 111-21. PMID 21208905 DOI: 10.1158/1078-0432.Ccr-10-2075 |
0.349 |
|
| 2011 |
Novokmet A, Baskin B, Malkin D. Li-Fraumeni syndrome: Retesting archival DNA samples to identify previously unrecognized germ-line p53 mutations. Journal of Clinical Oncology. 29: 1520-1520. DOI: 10.1200/Jco.2011.29.15_Suppl.1520 |
0.411 |
|
| 2011 |
Durno CA, Aronson M, Tabori U, Malkin D, Chan H, Gallinger S. Oncologic surveillance for subjects with biallelic mismatch repair gene mutations-10 year follow-up in a kindred Hereditary Cancer in Clinical Practice. 9: 11. DOI: 10.1186/1897-4287-9-S1-P11 |
0.318 |
|
| 2011 |
Wasserman JD, Novokmet A, Eichler-Jonsson C, Malkin D. Abstract 5351: Prevalence and function of p53 mutations among children with adrenocortical carcinoma (ADCC) Cancer Research. 71: 5351-5351. DOI: 10.1158/1538-7445.Am2011-5351 |
0.431 |
|
| 2011 |
Porat RM, Pasic I, Shlien A, Golgoz N, Andrulis I, Wunder JS, Malkin D. Abstract 5334: Genome-wide copy number analysis reveals two novel loci for susceptibility to sporadic osteosarcoma Cancer Research. 71: 5334-5334. DOI: 10.1158/1538-7445.Am2011-5334 |
0.71 |
|
| 2011 |
Merino DM, Shlien A, Pienkowska M, Tabori U, Malkin D. Abstract 3460: Genome-wide copy number analysis reveals novel somatic mutations associated with choroid plexus tumorigenesis Cancer Research. 71: 3460-3460. DOI: 10.1158/1538-7445.Am2011-3460 |
0.332 |
|
| 2010 |
Shlien A, Baskin B, Achatz MI, Stavropoulos DJ, Nichols KE, Hudgins L, Morel CF, Adam MP, Zhukova N, Rotin L, Novokmet A, Druker H, Shago M, Ray PN, Hainaut P, ... Malkin D, et al. A common molecular mechanism underlies two phenotypically distinct 17p13.1 microdeletion syndromes. American Journal of Human Genetics. 87: 631-42. PMID 21056402 DOI: 10.1016/J.Ajhg.2010.10.007 |
0.445 |
|
| 2010 |
Durbin AD, Pasic I, Wong DK, Hannigan GE, Malkin D. The oncogenic and growth-suppressive functions of the integrin-linked kinase are distinguished by JNK1 expression in human cancer cells. Cell Cycle (Georgetown, Tex.). 9: 1951-9. PMID 20495362 DOI: 10.4161/Cc.9.10.11554 |
0.671 |
|
| 2010 |
Tabori U, Shlien A, Baskin B, Levitt S, Ray P, Alon N, Hawkins C, Bouffet E, Pienkowska M, Lafay-Cousin L, Gozali A, Zhukova N, Shane L, Gonzalez I, Finlay J, ... Malkin D, et al. TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 1995-2001. PMID 20308654 DOI: 10.1200/Jco.2009.26.8169 |
0.455 |
|
| 2010 |
Tabori U, Baskin B, Shago M, Alon N, Taylor MD, Ray PN, Bouffet E, Malkin D, Hawkins C. Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 1345-50. PMID 20142599 DOI: 10.1200/Jco.2009.23.5952 |
0.395 |
|
| 2010 |
Pasic I, Shlien A, Durbin AD, Stavropoulos DJ, Baskin B, Ray PN, Novokmet A, Malkin D. Recurrent focal copy-number changes and loss of heterozygosity implicate two noncoding RNAs and one tumor suppressor gene at chromosome 3q13.31 in osteosarcoma. Cancer Research. 70: 160-71. PMID 20048075 DOI: 10.1158/0008-5472.Can-09-1902 |
0.696 |
|
| 2010 |
Shlien A, Malkin D. Copy number variations and cancer susceptibility. Current Opinion in Oncology. 22: 55-63. PMID 19952747 DOI: 10.1097/Cco.0B013E328333Dca4 |
0.327 |
|
| 2010 |
Somers GR, Ho M, Pienkowska M, Shlien A, Malkin D, Ackerley C, Zielenska M. IGF2 is highly expressed in pediatric undifferentiated sarcomas and reveals two distinct cytoplasmic trafficking patterns. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 13: 169-77. PMID 19586133 DOI: 10.2350/09-02-0613-Oa.1 |
0.308 |
|
| 2009 |
Malkin D. Prenatal diagnosis, preimplantation genetic diagnosis, and cancer: was Hamlet wrong? Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 4446-7. PMID 19704050 DOI: 10.1200/Jco.2009.23.9855 |
0.421 |
|
| 2009 |
Shlien A, Malkin D. Copy number variations and cancer. Genome Medicine. 1: 62. PMID 19566914 DOI: 10.1186/Gm62 |
0.364 |
|
| 2009 |
Gonzalez KD, Buzin CH, Noltner KA, Gu D, Li W, Malkin D, Sommer SS. High frequency of de novo mutations in Li-Fraumeni syndrome. Journal of Medical Genetics. 46: 689-93. PMID 19556618 DOI: 10.1136/Jmg.2008.058958 |
0.393 |
|
| 2009 |
Durbin AD, Somers GR, Forrester M, Pienkowska M, Hannigan GE, Malkin D. JNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcoma. The Journal of Clinical Investigation. 119: 1558-70. PMID 19478459 DOI: 10.1172/Jci37958 |
0.363 |
|
| 2008 |
Shlien A, Tabori U, Marshall CR, Pienkowska M, Feuk L, Novokmet A, Nanda S, Druker H, Scherer SW, Malkin D. Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome Proceedings of the National Academy of Sciences of the United States of America. 105: 11264-11269. PMID 18685109 DOI: 10.1073/Pnas.0802970105 |
0.448 |
|
| 2008 |
Tabori U, Malkin D. Risk stratification in cancer predisposition syndromes: lessons learned from novel molecular developments in Li-Fraumeni syndrome. Cancer Research. 68: 2053-7. PMID 18381406 DOI: 10.1158/0008-5472.Can-07-2091 |
0.432 |
|
| 2008 |
Strahm B, Durbin AD, Sexsmith E, Malkin D. The CXCR4-SDF1alpha axis is a critical mediator of rhabdomyosarcoma metastatic signaling induced by bone marrow stroma. Clinical & Experimental Metastasis. 25: 1-10. PMID 17768666 DOI: 10.1007/S10585-007-9094-6 |
0.337 |
|
| 2008 |
Durbin AD, Somers GR, Forrester M, Hannigan GE, Malkin D. OPPOSING FUNCTIONS FOR A PROTEIN KINASE: A JNK1 DEPENDENT SWITCH DETERMINES THE ONCOGENIC OR TUMOR SUPPRESSIVE ACTIVITY OF ILK INRHABDOMYOSARCOMA Clinical & Investigative Medicine. 31: 9. DOI: 10.25011/Cim.V31I4.4800 |
0.364 |
|
| 2007 |
Tabori U, Nanda S, Druker H, Lees J, Malkin D. Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome. Cancer Research. 67: 1415-8. PMID 17308077 DOI: 10.1158/0008-5472.Can-06-3682 |
0.43 |
|
| 2007 |
West AN, Neale GA, Pounds S, Figueredo BC, Rodriguez Galindo C, Pianovski MA, Oliveira Filho AG, Malkin D, Lalli E, Ribeiro R, Zambetti GP. Gene expression profiling of childhood adrenocortical tumors. Cancer Research. 67: 600-8. PMID 17234769 DOI: 10.1158/0008-5472.Can-06-3767 |
0.361 |
|
| 2007 |
Tabori U, Jones H, Malkin D. Low prevalence of complications in severe neutropenic children with cancer in the unprotected environment of an overnight camp. Pediatric Blood & Cancer. 48: 148-51. PMID 16421908 DOI: 10.1002/Pbc.20757 |
0.317 |
|
| 2006 |
Hendershot E, Pappo A, Malkin D, Sung L. Tumor necrosis in pediatric osteosarcoma: impact of modern therapies. Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses. 23: 176-81. PMID 16766682 DOI: 10.1177/1043454206289786 |
0.341 |
|
| 2006 |
Strahm B, Malkin D. Hereditary cancer predisposition in children: genetic basis and clinical implications. International Journal of Cancer. 119: 2001-6. PMID 16642469 DOI: 10.1002/Ijc.21962 |
0.474 |
|
| 2006 |
Tabori U, Vukovic B, Zielenska M, Hawkins C, Braude I, Rutka J, Bouffet E, Squire J, Malkin D. The role of telomere maintenance in the spontaneous growth arrest of pediatric low-grade gliomas. Neoplasia (New York, N.Y.). 8: 136-42. PMID 16611406 DOI: 10.1593/Neo.05715 |
0.359 |
|
| 2006 |
Tabori U, Ma J, Carter M, Zielenska M, Rutka J, Bouffet E, Bartels U, Malkin D, Hawkins C. Human Telomere Reverse Transcriptase Expression Predicts Progression and Survival in Pediatric Intracranial Ependymoma Journal of Clinical Oncology. 24: 1522-1528. PMID 16575002 DOI: 10.1200/Jco.2005.04.2127 |
0.362 |
|
| 2006 |
Ganjavi H, Gee M, Narendran A, Parkinson N, Krishnamoorthy M, Freedman MH, Malkin D. Adenovirus-mediated p53 gene therapy in osteosarcoma cell lines: sensitization to cisplatin and doxorubicin. Cancer Gene Therapy. 13: 415-9. PMID 16211088 DOI: 10.1038/Sj.Cgt.7700909 |
0.718 |
|
| 2005 |
Stickle NH, Cheng LS, Watson IR, Alon N, Malkin D, Irwin MS, Ohh M. Expression of p53 in renal carcinoma cells is independent of pVHL. Mutation Research. 578: 23-32. PMID 15998523 DOI: 10.1016/J.Mrfmmm.2005.02.016 |
0.374 |
|
| 2005 |
Ganjavi H, Gee M, Narendran A, Freedman MH, Malkin D. Adenovirus-mediated p53 gene therapy in pediatric soft-tissue sarcoma cell lines: sensitization to cisplatin and doxorubicin. Cancer Gene Therapy. 12: 397-406. PMID 15618970 DOI: 10.1038/Sj.Cgt.7700798 |
0.736 |
|
| 2004 |
Malkin D. Predictive genetic testing for childhood cancer: taking the road less traveled by. Journal of Pediatric Hematology Oncology. 26: 546-548. PMID 15342978 DOI: 10.1097/01.Mph.0000140650.65591.F1 |
0.318 |
|
| 2004 |
Narendran A, Hawkins LM, Ganjavi H, Vanek W, Gee MF, Barlow JW, Johnson G, Malkin D, Freedman MH. Characterization of bone marrow stromal abnormalities in a patient with constitutional trisomy 8 mosaicism and myelodysplastic syndrome. Pediatric Hematology and Oncology. 21: 209-21. PMID 15202160 DOI: 10.1080/08880010490276917 |
0.72 |
|
| 2004 |
Price V, Zielenska M, Smith C, Chilton-Macneill S, Malkin D, Pappo A. Clinical and molecular characteristics of pediatric gastrointestinal stromal tumors (GISTs) Journal of Clinical Oncology. 22: 8537-8537. DOI: 10.1200/Jco.2004.22.14_Suppl.8537 |
0.397 |
|
| 2003 |
Narendran A, Ganjavi H, Morson N, Connor A, Barlow JW, Keystone E, Malkin D, Freedman MH. Mutant p53 in bone marrow stromal cells increases VEGF expression and supports leukemia cell growth. Experimental Hematology. 31: 693-701. PMID 12901974 DOI: 10.1016/S0301-472X(03)00159-0 |
0.733 |
|
| 2002 |
Charoenkwan P, Senger C, Weitzman S, Sexsmith E, Sherman CG, Malkin D, Thorner PS. Significance of p53 expression in immature teratomas. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 5: 499-507. PMID 12202994 DOI: 10.1007/S10024-001-0268-Y |
0.364 |
|
| 2002 |
Ganjavi H, Malkin D. Genetics of childhood cancer. Clinical Orthopaedics and Related Research. 75-87. PMID 12151885 DOI: 10.1097/00003086-200208000-00011 |
0.763 |
|
| 2002 |
Dror Y, Durie P, Ginzberg H, Herman R, Banerjee A, Champagne M, Shannon K, Malkin D, Freedman MH. Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study. Experimental Hematology. 30: 659-69. PMID 12135662 DOI: 10.1016/S0301-472X(02)00815-9 |
0.316 |
|
| 2002 |
Leonard DG, Travis LB, Addya K, Dores GM, Holowaty EJ, Bergfeldt K, Malkin D, Kohler BA, Lynch CF, Wiklund T, Stovall M, Hall P, Pukkala E, Slater DJ, Felix CA. p53 mutations in leukemia and myelodysplastic syndrome after ovarian cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 973-85. PMID 12006509 |
0.303 |
|
| 2001 |
Malkin D. The role of p53 in human cancer. Journal of Neuro-Oncology. 51: 231-243. PMID 11407595 DOI: 10.1023/A:1010636426860 |
0.395 |
|
| 2000 |
Brown LT, Sexsmith E, Malkin D. Identification of a novel PTEN intronic deletion in Li-Fraumeni syndrome and its effect on RNA processing. Cancer Genetics and Cytogenetics. 123: 65-8. PMID 11120338 DOI: 10.1016/S0165-4608(00)00303-4 |
0.465 |
|
| 2000 |
Portwine C, Lees J, Verselis S, Li FP, Malkin D. Absence of germline p16(INK4a) alterations in p53 wild type Li-Fraumeni syndrome families. Journal of Medical Genetics. 37. PMID 10922393 DOI: 10.1136/Jmg.37.8.E13 |
0.693 |
|
| 2000 |
Theis JG, Chan HS, Greenberg ML, Malkin D, Karaskov V, Moncica I, Koren G, Doyle J. Assessment of systemic toxicity in children receiving chemotherapy with cyclosporine for sarcoma. Medical and Pediatric Oncology. 34: 242-9. PMID 10742059 DOI: 10.1002/(Sici)1096-911X(200004)34:4<242::Aid-Mpo2>3.0.Co;2-U |
0.329 |
|
| 2000 |
Malkin D, Brown EJ, Zipursky A. The role of p53 in megakaryocyte differentiation and the megakaryocytic leukemias of Down syndrome Cancer Genetics and Cytogenetics. 116: 1-5. PMID 10616523 DOI: 10.1016/S0165-4608(99)00072-2 |
0.381 |
|
| 1999 |
Lam V, McPherson JP, Salmena L, Lees J, Chu W, Sexsmith E, Hedley DW, Freedman MH, Reed JC, Malkin D, Goldenberg GJ. p53 gene status and chemosensitivity of childhood acute lymphoblastic leukemia cells to adriamycin Leukemia Research. 23: 871-880. PMID 10573131 DOI: 10.1016/S0145-2126(99)00102-2 |
0.325 |
|
| 1999 |
Quesnel S, Verselis S, Portwine C, Garber J, White M, Feunteun J, Malkin D, Li FP. p53 compound heterozygosity in a severely affected child with Li-Fraumeni syndrome. Oncogene. 18: 3970-8. PMID 10435620 DOI: 10.1038/Sj.Onc.1202783 |
0.721 |
|
| 1997 |
Quesnel S, Malkin D. Genetic predisposition to cancer and familial cancer syndromes. Pediatric Clinics of North America. 44: 791-808. PMID 9286285 DOI: 10.1016/S0031-3955(05)70530-7 |
0.477 |
|
| 1996 |
Malkin D, Knoppers BM. Genetic predisposition to cancer--issues to consider. Seminars in Cancer Biology. 7: 49-53. PMID 8695767 DOI: 10.1006/Scbi.1996.0007 |
0.342 |
|
| 1996 |
Malkin D. Age-specific oncogenesis: the genetics of cancer susceptibility. Environmental Health Perspectives. 37-9. PMID 8549486 DOI: 10.1289/Ehp.95103S637 |
0.428 |
|
| 1996 |
Felix C, Hosler M, Provisor D, Salhany K, Sexsmith E, Slater D, Cheung N, Winick N, Strauss E, Heyn R, Lange B, Malkin D. The p53 gene in pediatric therapy-related leukemia and myelodysplasia Blood. 87: 4376-4381. DOI: 10.1182/blood.V87.10.4376.bloodjournal87104376 |
0.348 |
|
| 1995 |
Diller L, Sexsmith E, Gottlieb A, Li FP, Malkin D. Germline p53 mutations are frequently detected in young children with rhabdomyosarcoma. The Journal of Clinical Investigation. 95: 1606-11. PMID 7706467 DOI: 10.1172/JCI117834 |
0.319 |
|
| 1995 |
Mousses S, Ozçelik H, Lee PD, Malkin D, Bull SB, Andrulis IL. Two variants of the CIP1/WAF1 gene occur together and are associated with human cancer. Human Molecular Genetics. 4: 1089-92. PMID 7655464 DOI: 10.1093/Hmg/4.6.1089 |
0.448 |
|
| 1994 |
Malkin D. Germline p53 gene mutations and cancer--Pandora's box or open sesame? Journal of the National Cancer Institute. 86: 326-8. PMID 8308919 DOI: 10.1093/Jnci/86.5.326 |
0.405 |
|
| 1994 |
Malkin D, Friend SH. Screening for cancer susceptibility in children. Current Opinion in Pediatrics. 6: 46-51. PMID 8205174 DOI: 10.1097/00008480-199402000-00009 |
0.453 |
|
| 1994 |
Wagner J, Portwine C, Rabin K, Leclerc JM, Narod SA, Malkin D. High frequency of germline p53 mutations in childhood adrenocortical cancer. Journal of the National Cancer Institute. 86: 1707-10. PMID 7966399 DOI: 10.1093/Jnci/86.22.1707 |
0.724 |
|
| 1993 |
Malkin D. p53 and the Li-Fraumeni syndrome. Cancer Genetics and Cytogenetics. 66: 83-92. PMID 8500106 DOI: 10.1016/0165-4608(93)90233-C |
0.445 |
|
| 1993 |
Malkin D, Friend SH. Correction: A Li-Fraumeni Syndrome p53 Mutation Science. 259: 878-878. DOI: 10.1126/Science.259.5097.878B |
0.345 |
|
| 1992 |
McIntyre JF, Gebhardt MC, Smith-Sorensen B, Piraux NB, Malkin D, Friend SH. Germline mutations of the p53 tumor suppressor gene in children with osteosarcoma International Journal of Radiation Oncology Biology Physics. 24: 267. DOI: 10.1016/0360-3016(92)90370-W |
0.419 |
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| Show low-probability matches. |