| Year |
Citation |
Score |
| 2020 |
Saxena AK, Alam M. ATP Synthase Inhibitors as Anti-tubercular Agents: QSAR Studies in Novel Substituted Quinolines. Current Topics in Medicinal Chemistry. PMID 32885753 DOI: 10.2174/1568026620666200903163515 |
0.349 |
|
| 2019 |
Varshney K, Gupta AK, Rawat A, Srivastava R, Mishra A, Saxena M, Srivastava AK, Jain S, Saxena AK. Synthesis, SAR and Docking Studies of Substituted Aryl phenylthiazolyl phenylcarboxamide as potential Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors. Chemical Biology & Drug Design. PMID 30903642 DOI: 10.1111/Cbdd.13515 |
0.432 |
|
| 2018 |
Varshney K, Gupta AK, Sonkar R, Varshney S, Mishra A, Bhatia G, Gaikwad A, Srivastava AK, Saxena M, Jain S, Saxena AK. Lipid Lowering Oxopropanylindole Hydrazone Derivatives with Anti-oxidant and Anti-hyperglycemic Activity. Current Topics in Medicinal Chemistry. PMID 30569857 DOI: 10.2174/1568026619666181220112903 |
0.381 |
|
| 2018 |
Tsolaki E, Eleftheriou P, Kartsev V, Geronikaki A, Saxena AK. Application of Docking Analysis in the Prediction and Biological Evaluation of the Lipoxygenase Inhibitory Action of Thiazolyl Derivatives of Mycophenolic Acid. Molecules (Basel, Switzerland). 23. PMID 29970872 DOI: 10.3390/Molecules23071621 |
0.383 |
|
| 2017 |
Gupta AK, Varshney K, Kumar V, Srivastava K, Pant AB, Puri SK, Saxena AK. Design, Synthesis, and Biological Evaluation of Novel 1,2,4-Trioxanes as Potential Antimalarial Agents. Archiv Der Pharmazie. PMID 28207169 DOI: 10.1002/Ardp.201600335 |
0.387 |
|
| 2017 |
Azad CS, Saxena M, Siddiqui AJ, Bhardwaj J, Puri SK, Dutta GP, Anand N, Saxena AK. Synthesis of Primaquine Glyco-conjugates as potential tissue-schizontocidal antimalarial agents. Chemical Biology & Drug Design. PMID 28102941 DOI: 10.1111/Cbdd.12944 |
0.775 |
|
| 2016 |
Bhateria M, Ramakrishna R, Puttrevu SK, Saxena AK, Bhatta RS. Enantioselective inhibition of Cytochrome P450-mediated drug metabolism by a novel antithrombotic agent, S002-333: Major effect on CYP2B6. Chemico-Biological Interactions. PMID 27387538 DOI: 10.1016/J.Cbi.2016.07.001 |
0.34 |
|
| 2016 |
Shakya AK, Kamal M, Balaramnavar VM, Bardaweel SK, Naik RR, Saxena AK, Siddiqui HH. Design, synthesis and evaluation of benzofuran-acetamide scaffold as potential anticonvulsant agent. Acta Pharmaceutica (Zagreb, Croatia). 66: 353-372. PMID 27383885 DOI: 10.1515/Acph-2016-0023 |
0.422 |
|
| 2016 |
Tratrat C, Haroun M, Paparisva A, Geronikaki A, Kamoutsis C, Ćirić A, Glamočlija J, Soković M, Fotakis C, Zoumpoulakis P, Bhunia SS, Saxena AK. Design, synthesis and biological evaluation of new substituted 5-benzylideno-2-adamantylthiazol[3,2-b][1,2,4]triazol-6(5H)ones. Pharmacophore models for antifungal activity Arabian Journal of Chemistry. 11: 573-590. DOI: 10.1016/J.Arabjc.2016.06.007 |
0.461 |
|
| 2015 |
Sashidhara KV, Avula SR, Doharey PK, Singh LR, Balaramnavar VM, Gupta J, Misra-Bhattacharya S, Rathaur S, Saxena AK, Saxena JK. Designing, synthesis of selective and high-affinity chalcone-benzothiazole hybrids as Brugia malayi thymidylate kinase inhibitors: In vitro validation and docking studies. European Journal of Medicinal Chemistry. 103: 418-28. PMID 26383126 DOI: 10.1016/J.Ejmech.2015.09.004 |
0.388 |
|
| 2015 |
Bhunia SS, Singh S, Saxena S, Saxena AK. Pharmacophore Modeling, Docking and Molecular Dynamics Studies on Caspase-3 Activators Binding at β-tubulin Site. Current Computer-Aided Drug Design. PMID 26126610 DOI: 10.2174/1573409911666150701103342 |
0.322 |
|
| 2015 |
Singh S, Roy KK, Khan SR, Kashyap VK, Sharma A, Jaiswal S, Sharma SK, Krishnan MY, Chaturvedi V, Lal J, Sinha S, Gupta AD, Srivastava R, Saxena AK. Novel, potent, orally bioavailable and selective mycobacterial ATP synthase inhibitors that demonstrated activity against both replicating and non-replicating M. tuberculosis. Bioorganic & Medicinal Chemistry. 23: 742-52. PMID 25614114 DOI: 10.1016/J.Bmc.2014.12.060 |
0.353 |
|
| 2015 |
Gupta AK, Saxena AK. Molecular modelling based target identification for endo-peroxides class of antimalarials. Combinatorial Chemistry & High Throughput Screening. 18: 199-207. PMID 25543685 DOI: 10.2174/1386207318666141229124112 |
0.307 |
|
| 2015 |
Azad CS, Balaramnavar VM, Khan IA, Doharey PK, Saxena JK, Saxena AK. Operative conversions of 3-carboxy-4-quinolones into 3-nitro-4-quinolones via ipso-nitration: Potential antifilarial agents as inhibitors of Brugia malayi thymidylate kinase Rsc Advances. 5: 82208-82214. DOI: 10.1039/C5Ra18036H |
0.723 |
|
| 2015 |
Azad CS, Saxena AK. Stereoconvergent synthesis of 1-deoxynojirimycin isomers by using the 3 component 4 centred Ugi reaction Organic Chemistry Frontiers. 2: 665-669. DOI: 10.1039/C5Qo00019J |
0.72 |
|
| 2015 |
Kalia D, Anil Kumar KS, Meena G, Sethi KP, Sharma R, Trivedi P, Khan SR, Verma AS, Singh S, Sharma S, Roy KK, Kant R, Krishnan MY, Singh BN, Sinha S, ... ... Saxena AK, et al. Synthesis and anti-tubercular activity of conformationally-constrained and bisquinoline analogs of TMC207 Medchemcomm. 6: 1554-1563. DOI: 10.1039/C5Md00131E |
0.409 |
|
| 2015 |
Pitta E, Tsolaki E, Geronikaki A, Petrović J, Glamočlija J, Soković M, Crespan E, Maga G, Bhunia SS, Saxena AK. 4-Thiazolidinone derivatives as potent antimicrobial agents: Microwave-assisted synthesis, biological evaluation and docking studies Medchemcomm. 6: 319-326. DOI: 10.1039/C4Md00399C |
0.438 |
|
| 2014 |
Azad CS, Bhunia SS, Krishna A, Shukla PK, Saxena AK. Novel Glycoconjugate of 8-Fluoro Norfloxacin Derivatives as Gentamicin-resistant Staphylococcus aureus Inhibitors: Synthesis and Molecular Modelling Studies. Chemical Biology & Drug Design. PMID 25546316 DOI: 10.1111/Cbdd.12503 |
0.716 |
|
| 2014 |
Balaramnavar VM, Srivastava R, Rahuja N, Gupta S, Rawat AK, Varshney S, Chandasana H, Chhonker YS, Doharey PK, Kumar S, Gautam S, Srivastava SP, Bhatta RS, Saxena JK, Gaikwad AN, ... ... Saxena AK, et al. Identification of novel PTP1B inhibitors by pharmacophore based virtual screening, scaffold hopping and docking. European Journal of Medicinal Chemistry. 87: 578-94. PMID 25299681 DOI: 10.1016/J.Ejmech.2014.09.097 |
0.36 |
|
| 2014 |
Doharey PK, Suthar MK, Verma A, Kumar V, Yadav S, Balaramnavar VM, Rathaur S, Saxena AK, Siddiqi MI, Saxena JK. Molecular cloning and characterization of Brugia malayi thymidylate kinase. Acta Tropica. 133: 83-92. PMID 24556140 DOI: 10.1016/J.Actatropica.2014.02.003 |
0.301 |
|
| 2014 |
Mishra SK, Tiwari S, Shrivastava A, Srivastava S, Boudh GK, Chourasia SK, Chaturvedi U, Mir SS, Saxena AK, Bhatia G, Lakshmi V. Antidyslipidemic effect and antioxidant activity of anthraquinone derivatives from Rheum emodi rhizomes in dyslipidemic rats. Journal of Natural Medicines. 68: 363-71. PMID 24343839 DOI: 10.1007/S11418-013-0810-Z |
0.32 |
|
| 2014 |
Patel GK, Gupta AK, Gupta A, Mishra M, Singh PK, Saxena AK, Sharma AK. Purification and physicochemical characterization of a trypsin inhibitor from Cassia absus Linn. Protein and Peptide Letters. 21: 108-14. PMID 24168474 DOI: 10.2174/09298665113209990090 |
0.303 |
|
| 2014 |
Hussain MK, Ansari MI, Yadav N, Gupta PK, Gupta AK, Saxena R, Fatima I, Manohar M, Kushwaha P, Khedgikar V, Gautam J, Kant R, Maulik PR, Trivedi R, Dwivedi A, ... ... Saxena AK, et al. Design and synthesis of ERα/ERβ selective coumarin and chromene derivatives as potential anti-breast cancer and anti-osteoporotic agents Rsc Advances. 4: 8828-8845. DOI: 10.1039/C3Ra45749D |
0.386 |
|
| 2013 |
Srivastava S, Sonkar R, Mishra SK, Tiwari A, Balaramnavar VM, Balramnavar V, Mir S, Bhatia G, Saxena AK, Lakshmi V. Antidyslipidemic and antioxidant effects of novel Lupeol-derived chalcones. Lipids. 48: 1017-27. PMID 23943005 DOI: 10.1007/S11745-013-3824-0 |
0.402 |
|
| 2013 |
Saxena AK, Roy KK, Singh S, Vishnoi SP, Kumar A, Kashyap VK, Kremer L, Srivastava R, Srivastava BS. Identification and characterisation of small-molecule inhibitors of Rv3097c-encoded lipase (LipY) of Mycobacterium tuberculosis that selectively inhibit growth of bacilli in hypoxia. International Journal of Antimicrobial Agents. 42: 27-35. PMID 23684389 DOI: 10.1016/J.Ijantimicag.2013.03.007 |
0.345 |
|
| 2013 |
Kumar S, Dwivedi AP, Kashyap VK, Saxena AK, Dwivedi AK, Srivastava R, Sahu DP. Synthesis and biological evaluation of trans 6-methoxy-1,1-dimethyl-2-phenyl-3-aryl-2,3-dihydro-1H-inden-4-yloxyalkylamine derivatives against drug susceptible, non-replicating M. tuberculosis H37Rv and clinical multidrug resistant strains. Bioorganic & Medicinal Chemistry Letters. 23: 2404-7. PMID 23474387 DOI: 10.1016/J.Bmcl.2013.02.030 |
0.389 |
|
| 2013 |
Gupta AK, Varshney K, Singh N, Mishra V, Saxena M, Palit G, Saxena AK. Identification of novel amino acid derived CCK-2R antagonists as potential antiulcer agent: homology modeling, design, synthesis, and pharmacology. Journal of Chemical Information and Modeling. 53: 176-87. PMID 23240656 DOI: 10.1021/Ci3003655 |
0.341 |
|
| 2013 |
Gupta AK, Saxena AK. Triple-layered QSAR studies on substituted 1,2,4-trioxanes as potential antimalarial agents: superiority of the quantitative pharmacophore-based alignment over common substructure-based alignment Sar and Qsar in Environmental Research. 24: 119-134. PMID 23194465 DOI: 10.1080/1062936X.2012.742136 |
0.357 |
|
| 2013 |
Khan SR, Singh S, Roy KK, Akhtar MS, Saxena AK, Krishnan MY. Biological evaluation of novel substituted chloroquinolines targeting mycobacterial ATP synthase. International Journal of Antimicrobial Agents. 41: 41-6. PMID 23141113 DOI: 10.1016/J.Ijantimicag.2012.09.012 |
0.376 |
|
| 2013 |
Ochieng CO, Shrivastava A, Chaturvedi U, Sonkar R, Khanna AK, Bhatia G, Asthana RK, Owuor PO, Manguro LA, Saxena AK. Effects of Senna didymobotrya Root Extract and Compounds on Tritoninduced Hyperlipidaemic Rats and Differentiation of 3T3-Li Preadipocytes The Natural Products Journal. 3: 212-217. DOI: 10.2174/22103155113039990011 |
0.32 |
|
| 2013 |
Gupta S, Varshney K, Srivastava R, Rahuja N, Rawat AK, Srivastava AK, Saxena AK. Identification of novel urea derivatives as PTP1B inhibitors: synthesis, biological evaluation and structure–activity relationships Medchemcomm. 4: 1382-1387. DOI: 10.1039/C3Md00138E |
0.39 |
|
| 2013 |
Azad CS, Saxena AK. One pot conversion of carbohydrates alcohol into chloride via benzotriazole sulfonate Tetrahedron. 69: 2608-2612. DOI: 10.1016/J.Tet.2013.01.044 |
0.718 |
|
| 2013 |
Srivastava S, Sonkar R, Mishra SK, Tiwari A, Balaramnavar VM, Mir S, Bhatia G, Saxena AK, Lakshmi V. Erratum to: Antidyslipidemic and Antioxidant Effects of Novel Lupeol-Derived Chalcones Lipids. 48: 1297-1297. DOI: 10.1007/S11745-013-3846-7 |
0.323 |
|
| 2012 |
Roy KK, Tota S, Tripathi T, Chander S, Nath C, Saxena AK. Lead optimization studies towards the discovery of novel carbamates as potent AChE inhibitors for the potential treatment of Alzheimer's disease. Bioorganic & Medicinal Chemistry. 20: 6313-20. PMID 23026084 DOI: 10.1016/J.Bmc.2012.09.005 |
0.371 |
|
| 2012 |
Balaramnavar VM, Khan IA, Siddiqui JA, Khan MP, Chakravarti B, Sharan K, Swarnkar G, Rastogi N, Siddiqui HH, Mishra DP, Chattopadhyay N, Saxena AK. Identification of novel 2-((1-(benzyl(2-hydroxy-2-phenylethyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamoyl)benzoic acid analogues as BMP-2 stimulators. Journal of Medicinal Chemistry. 55: 8248-59. PMID 22978808 DOI: 10.1021/Jm300985D |
0.391 |
|
| 2012 |
Gupta AK, Varshney K, Saxena AK. Toward the identification of a reliable 3D QSAR pharmacophore model for the CCK2 receptor antagonism. Journal of Chemical Information and Modeling. 52: 1376-90. PMID 22530718 DOI: 10.1021/Ci300094E |
0.33 |
|
| 2012 |
Khare P, Gupta AK, Gajula PK, Sunkari KY, Jaiswal AK, Das S, Bajpai P, Chakraborty TK, Dube A, Saxena AK. Identification of novel S-adenosyl-L-homocysteine hydrolase inhibitors through homology-model-based virtual screening, synthesis, and biological evaluation. Journal of Chemical Information and Modeling. 52: 777-91. PMID 22324915 DOI: 10.1021/Ci2005862 |
0.361 |
|
| 2012 |
Eleftheriou P, Geronikaki A, Hadjipavlou-Litina D, Vicini P, Filz O, Filimonov D, Poroikov V, Chaudhaery SS, Roy KK, Saxena AK. Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors. European Journal of Medicinal Chemistry. 47: 111-24. PMID 22119153 DOI: 10.1016/J.Ejmech.2011.10.029 |
0.357 |
|
| 2012 |
Khan IA, Balaramnavar VM, Saxena AK. Identification and optimization of novel pyrimido-isoxazolidine and oxazine as selective hydride donors Tetrahedron. 68: 10122-10129. DOI: 10.1016/J.Tet.2012.09.105 |
0.349 |
|
| 2012 |
Khan IA, Saxena AK. Employing lactams for the unprecedented enantiopure synthesis of non-natural amino acid derivatives Tetrahedron. 68: 1272-1279. DOI: 10.1016/J.Tet.2011.11.047 |
0.339 |
|
| 2012 |
Khan IA, Saxena AK. Parikh–Doering oxidation–dehydration–Ugi cyclization cascade in the development of lactams from formidoalkanols (3>chain length>7) Tetrahedron. 68: 294-299. DOI: 10.1016/J.Tet.2011.10.050 |
0.322 |
|
| 2011 |
Sharma S, Pandey AK, Shukla PK, Saxena AK. Synthesis and 2D QSAR of O-sulphonated β-aminols derivatives as novel antifungal and antibacterial agents. Bioorganic & Medicinal Chemistry Letters. 21: 6476-81. PMID 21920743 DOI: 10.1016/J.Bmcl.2011.08.078 |
0.367 |
|
| 2011 |
Roy KK, Singh S, Sharma SK, Srivastava R, Chaturvedi V, Saxena AK. Synthesis and biological evaluation of substituted 4-arylthiazol-2-amino derivatives as potent growth inhibitors of replicating Mycobacterium tuberculosis H₃₇Rv. Bioorganic & Medicinal Chemistry Letters. 21: 5589-93. PMID 21783364 DOI: 10.1016/J.Bmcl.2011.06.076 |
0.446 |
|
| 2011 |
Bhunia SS, Roy KK, Saxena AK. Profiling the structural determinants for the selectivity of representative factor-Xa and thrombin inhibitors using combined ligand-based and structure-based approaches. Journal of Chemical Information and Modeling. 51: 1966-85. PMID 21761917 DOI: 10.1021/Ci200185Q |
0.301 |
|
| 2011 |
Roy KK, Bhunia SS, Saxena AK. CoMFA, CoMSIA, and docking studies on thiolactone-class of potent anti-malarials: identification of essential structural features modulating anti-malarial activity. Chemical Biology & Drug Design. 78: 483-93. PMID 21672165 DOI: 10.1111/J.1747-0285.2011.01158.X |
0.375 |
|
| 2010 |
Gupta S, Pandey G, Rahuja N, Srivastava AK, Saxena AK. Design, synthesis and docking studies on phenoxy-3-piperazin-1-yl-propan-2-ol derivatives as protein tyrosine phosphatase 1B inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 5732-4. PMID 20797859 DOI: 10.1016/J.Bmcl.2010.08.008 |
0.412 |
|
| 2010 |
Gupta AK, Chakroborty S, Srivastava K, Puri SK, Saxena AK. Pharmacophore modeling of substituted 1,2,4-Trioxanes for quantitative prediction of their antimalarial activity. Journal of Chemical Information and Modeling. 50: 1510-20. PMID 20726605 DOI: 10.1021/Ci100180E |
0.356 |
|
| 2010 |
Chaudhaery SS, Roy KK, Shakya N, Saxena G, Sammi SR, Nazir A, Nath C, Saxena AK. Novel carbamates as orally active acetylcholinesterase inhibitors found to improve scopolamine-induced cognition impairment: pharmacophore-based virtual screening, synthesis, and pharmacology. Journal of Medicinal Chemistry. 53: 6490-505. PMID 20684567 DOI: 10.1021/Jm100573Q |
0.358 |
|
| 2010 |
Singh S, Mandal PK, Singh N, Misra AK, Singh S, Chaturvedi V, Sinha S, Saxena AK. Substituted hydrazinecarbothioamide as potent antitubercular agents: synthesis and quantitative structure-activity relationship (QSAR). Bioorganic & Medicinal Chemistry Letters. 20: 2597-600. PMID 20304645 DOI: 10.1016/J.Bmcl.2010.02.081 |
0.423 |
|
| 2010 |
Geronikaki AA, Bennamane N, Nedjar-Kolli B, Eleftheriou PT, Kaoua R, Boubekeur K, Hoffman P, Chaudhaery SS, Saxena AK. N-substituted [phenyl-pyrazolo]-oxazin-2-thiones as COX-LOX inhibitors: influence of the replacement of the oxo -group with thioxo- group on the COX inhibition activity of N-substituted pyrazolo-oxazin-2-ones Arkivoc. 2011. DOI: 10.3998/Ark.5550190.0012.206 |
0.404 |
|
| 2010 |
TRIPATHI RC, SINGH HK, PATNAIK GK, SAXENA AK. ChemInform Abstract: Synthesis and SAR in 1-Substituted-4- [4-fluorobenzoyl/6,7-dimethoxy-3,4-dihydroisoquinolyl]piperidines and Related Compounds. Cheminform. 29: no-no. DOI: 10.1002/CHIN.199836187 |
0.301 |
|
| 2010 |
SHUKLA UK, SINGH R, KHANNA JM, SAXENA AK, SINGH HK, SUR RN, DHAWAN BN, ANAND N. ChemInform Abstract: Synthesis of trans-2-(N-(2-Hydroxy-1,2,3,4-tetrahydronaphthalene-1-yl)) iminothiazolidine and Related Compounds - A New Class of Antidepressants. Cheminform. 23: no-no. DOI: 10.1002/CHIN.199222156 |
0.563 |
|
| 2009 |
Chaudhaery SS, Roy KK, Saxena AK. Consensus superiority of the pharmacophore-based alignment, over maximum common substructure (MCS): 3D-QSAR studies on carbamates as acetylcholinesterase inhibitors. Journal of Chemical Information and Modeling. 49: 1590-601. PMID 19441865 DOI: 10.1021/Ci900049E |
0.33 |
|
| 2009 |
Saxena AK, Pandey G, Gupta S, Singh AB, Srivastava AK. Synthesis of protein tyrosine phosphatase 1B inhibitors: model validation and docking studies. Bioorganic & Medicinal Chemistry Letters. 19: 2320-3. PMID 19282172 DOI: 10.1016/J.Bmcl.2009.02.058 |
0.408 |
|
| 2008 |
Dixit A, Saxena AK. QSAR analysis of PPAR-γ agonists as anti-diabetic agents European Journal of Medicinal Chemistry. 43: 73-80. PMID 17482722 DOI: 10.1016/J.Ejmech.2007.03.004 |
0.355 |
|
| 2008 |
Singh S, Saxena AK. 2D-QSAR of purine-scaffold novel class of Hsp90 binders that inhibit the proliferation of cancer cells Medicinal Chemistry Research. 17: 290-296. DOI: 10.1007/S00044-007-9064-1 |
0.336 |
|
| 2008 |
Tripathi T, Saxena AK. 2D- QSAR studies on new stilbene derivatives of resveratrol as a new selective aryl hydrocarbon receptor Medicinal Chemistry Research. 17: 212-218. DOI: 10.1007/S00044-007-9055-2 |
0.347 |
|
| 2007 |
Chakrabarty R, Rao J, Anand A, Roy AD, Roy R, Shankar G, Dua PR, Saxena AK. Rational design, synthesis and evaluation of (6aR( *),11bS( *))-1-(4-fluorophenyl)-4-{7-[4-(4-fluorophenyl)-4-oxobutyl]1,2,3,4,6,6a,7,11b,12,12a(RS)-decahydropyrazino[2',1':6,1]pyrido[3,4-b]indol-2-yl}-butan-1-one as a potential neuroleptic agent. Bioorganic & Medicinal Chemistry. 15: 7361-7. PMID 17869521 DOI: 10.1016/J.Bmc.2007.07.018 |
0.343 |
|
| 2007 |
Saxena AK, Rao J, Chakrabarty R, Saxena M, Srimal RC. Synthesis and QSAR studies on hypotensive 1-[3-(4-substituted phenylthio) propyl]-4-(substituted phenyl) piperazines. Bioorganic & Medicinal Chemistry Letters. 17: 1708-12. PMID 17234413 DOI: 10.1016/J.Bmcl.2006.12.072 |
0.388 |
|
| 2007 |
Sharma P, Singh S, Siddiqui TI, Singh VS, Kundu B, Prathipati P, Saxena AK, Dikshit DK, Rastogi L, Dixit C, Gupta MB, Patnaik GK, Dikshit M. alpha-Amino acid derivatives as proton pump inhibitors and potent anti-ulcer agents. European Journal of Medicinal Chemistry. 42: 386-93. PMID 17045703 DOI: 10.1016/J.Ejmech.2006.08.016 |
0.767 |
|
| 2007 |
Anand A, Roy AD, Chakrabarty R, Saxena AK, Roy R. Investigation of the barrier to the rotation of carbamate and amide C–N bonds in antidepressant (6aR∗,11bS∗)-7-[carbobenzyloxy-l-alanyl]-2-[(4-methylphenyl)sulfonyl]-1,2,3,4,6,6a,7,11b,2,12a(S)-decahydropyrazino[2′,1′:6,1]pyrido[3,4-b]indole by dynamic NMR and molecular mechanics Tetrahedron. 63: 5236-5243. DOI: 10.1016/J.Tet.2007.03.171 |
0.304 |
|
| 2006 |
Saxena M, Gaur S, Prathipati P, Saxena AK. Synthesis of some substituted pyrazinopyridoindoles and 3D QSAR studies along with related compounds: piperazines, piperidines, pyrazinoisoquinolines, and diphenhydramine, and its semi-rigid analogs as antihistamines (H1). Bioorganic & Medicinal Chemistry. 14: 8249-58. PMID 17010624 DOI: 10.1016/J.Bmc.2006.09.018 |
0.412 |
|
| 2004 |
Lakshmi V, Saxena A, Pandey K, Bajpai P, Misra-Bhattacharya S. Antifilarial activity of Zoanthus species (Phylum Coelenterata, Class Anthzoa) against human lymphatic filaria, Brugia malayi. Parasitology Research. 93: 268-273. PMID 15258853 DOI: 10.1007/S00436-004-1124-6 |
0.302 |
|
| 2004 |
Rathi L, Kashaw SK, Dixit A, Pandey G, Saxena AK. Pharmacophore identification and 3D-QSAR studies in N-(2-benzoyl phenyl)-l-tyrosines as PPARγ agonists Bioorganic & Medicinal Chemistry. 12: 63-69. PMID 14697771 DOI: 10.1016/J.Bmc.2003.10.032 |
0.307 |
|
| 2004 |
Rao J, Chakrabarty R, Roy R, Mishra A, Saxena AK. A convenient regiospecific synthesis of substituted 1,3,4,6,6a, 11b,12,12a-octahydro-2H,7H-pyrazino[2′1′:6,1]pyrido(3,4-b)indoles Arkivoc. 2005. DOI: 10.3998/Ark.5550190.0006.203 |
0.325 |
|
| 2004 |
Shakya N, Fatima Z, Saxena AK. 3D-QSAR STUDIES ON SUBSTITUTED DIHYDROPYRIDINES FOR THEIR α1A-ADRENERGIC RECEPTOR BINDING AFFINITY Medicinal Chemistry Research. 13: 812-823. DOI: 10.1007/S00044-004-0120-9 |
0.335 |
|
| 2004 |
Awasthis KK, Chakrabarty R, Saxena AK. A CONVENIENT ROUTE FOR THE SYNTHESIS OF CIS-1-SUBSTITUTED 1,2,3,4,4a,5,11,11a-OCTAHYDRO-6H-PYRIDO[3,2-b]CARBAZOLES AND 4-SUBSTITUTED 1,2,3,4,4a,5,6,11c-OCTAHYDRO-7H-PYRIDO[2,3-c] CARBAZOLES AS POTENT DOPAMINE AGONISTS Medicinal Chemistry Research. 13: 758-769. DOI: 10.1007/S00044-004-0115-6 |
0.352 |
|
| 2004 |
Srivastava S, Bhandari K, Shankar G, Singh HK, Saxena AK. Synthesis, Anorexigenic Activity And Qsar Of Substituted Aryloxypropanolamines Medicinal Chemistry Research. 13: 631-642. DOI: 10.1007/S00044-004-0107-6 |
0.38 |
|
| 2003 |
Saxena AK, Ram S, Saxena M, Singh N, Prathipati P, Jain PC, Singh HK, Anand N. QSAR studies in substituted 1,2,3,4,6,7,12,12a-octa-hydropyrazino[2',1':6,1]pyrido[3,4-b]indoles--a potent class of neuroleptics. Bioorganic & Medicinal Chemistry. 11: 2085-90. PMID 12670659 DOI: 10.1016/S0968-0896(02)00652-1 |
0.574 |
|
| 2003 |
Saxena AK, Schaper K. QSAR analysis of the time dependent hypotensive activity of 1-[3-(4-substituted phenylthio)propyl]-4-(3,4-substituted phenyl)piperazines using Artificial Neural Networks Qsar & Combinatorial Science. 22: 965-983. DOI: 10.1002/Qsar.200330850 |
0.304 |
|
| 2003 |
Pardasani RT, Pardasani P, Chaturvedi V, Yadav SK, Saxena A, Sharma I. Theoretical and synthetic approach to novel spiroheterocycles derived from isatin derivatives and L‐proline via 1,3‐dipolar cycloaddition Heteroatom Chemistry. 14: 36-41. DOI: 10.1002/Hc.10063 |
0.324 |
|
| 2002 |
Gupta MK, Mishra P, Prathipati P, Saxena AK. 2D-QSAR in hydroxamic acid derivatives as peptide deformylase inhibitors and antibacterial agents. Bioorganic & Medicinal Chemistry. 10: 3713-6. PMID 12413827 DOI: 10.1016/S0968-0896(02)00421-2 |
0.343 |
|
| 2002 |
Sharma I, Saxena A, Ojha CK, Pardasani P, Pardasani RT, Mukherjee T. A comprehensive approach to the photochemical synthesis of bioactive compounds by the reaction of oxazolidine, thiazolidine and pyrazolidine derivatives with indol-2,3-diones Journal of Chemical Sciences. 114: 523-531. DOI: 10.1007/Bf02708846 |
0.375 |
|
| 2001 |
Pandey SK, Naware NB, Trivedi P, Saxena AK. Molecular modeling and 3D-QSAR studies in 2-aziridinyl-and 2,3-bis(aziridinyl)-1,4-naphthoquinonyl sulfonate and acylate derivatives as potential antimalarial agents. Sar and Qsar in Environmental Research. 12: 547-564. PMID 11813805 DOI: 10.1080/10629360108039834 |
0.351 |
|
| 2001 |
Saxena AK, Pandey SK, Seth P, Singh MP, Dikshit M, Carpy A. Synthesis and QSAR studies in 2-(N-aryl-N-aroyl)amino-4,5-dihydrothiazole derivatives as potential antithrombotic agents Bioorganic & Medicinal Chemistry. 9: 2025-2034. PMID 11504639 DOI: 10.1016/S0968-0896(01)00082-7 |
0.387 |
|
| 2001 |
Saxena AK, Pandey SK, Tripathi RC, Raghubir R. Synthesis, molecular modeling and QSAR studies in chiral 2,3-disubstituted-1,2,3,4-tetrahydro-9H-pyrido(3,4-b)indoles as potential modulators of opioid antinociception. Bioorganic & Medicinal Chemistry. 9: 1559-1570. PMID 11408175 DOI: 10.1016/S0968-0896(01)00042-6 |
0.375 |
|
| 2000 |
Singh RB, Gupta DC, Bajpai UC, Saxena M, Saxena AK. Fourier transform infrared spectra and normal mode analysis of 1-[(3-methyl phenyl) piperazin-1-yl]-3-[thio(4-acetamido-phenyl]propane: a potent 5-HT2 and D2 receptor ligand Spectrochimica Acta Part a: Molecular and Biomolecular Spectroscopy. 56: 1267-1275. PMID 10888431 DOI: 10.1016/S1386-1425(99)00224-3 |
0.327 |
|
| 1999 |
Tripathi RC, Pandey SK, Kar K, Dikshit M, Saxena AK. Synthesis and SAR studies of 1-substituted-n-(4-alkoxycarbonylpiperidin-1-yl)alkanes as potent antiarrhythmic agents. Bioorganic & Medicinal Chemistry Letters. 9: 2693-8. PMID 10509918 DOI: 10.1016/S0960-894X(99)00456-4 |
0.446 |
|
| 1999 |
Seydel JK, Bürger H, Saxena AK, Coleman MD, Smith SN, Perris AD. Quantitative structure-activity and structure-toxicity relationships of 4-aminodiphenyl sulphone derivatives with antiinflammatory activity Quantitative Structure-Activity Relationships. 18: 43-51. DOI: 10.1002/(Sici)1521-3838(199901)18:1<43::Aid-Qsar43>3.0.Co;2-# |
0.365 |
|
| 1992 |
Shukla UK, Singh R, Khanna JM, Saxena AK, Singh HK, Sur RN, Dhawan BN, Anand N. Synthesis of trans -2-[ N -(2-Hydroxy-1,2,3,4-tetrahydronaphthalene-1-yl)]iminothiazolidine and Related Compounds - A New Class of Antidepressants Collection of Czechoslovak Chemical Communications. 57: 415-424. DOI: 10.1135/Cccc19920415 |
0.606 |
|
| 1990 |
Saxena M, Agarwal SK, Patnaik GK, Saxena AK. Synthesis, biological evaluation, and quantitative structure-activity relationship analysis of [β-(aroylamino)ethyl]piperazines and -piperidines and [2-[(arylamino)carbonyl]ethyl]piperazines, -piperidines, -pyrazinopyridoindoles, and -pyrazinoisoquinolines. A new class of potent H1 antagonists Journal of Medicinal Chemistry. 33: 2970-2976. PMID 1977909 DOI: 10.1021/Jm00173A011 |
0.404 |
|
| 1987 |
Saxena AK, Sinha S. Pyrimidinones as biodynamic agents Progress in Drug Research. 31: 127-160. PMID 2894039 DOI: 10.1007/978-3-0348-9289-6_3 |
0.311 |
|
| 1985 |
GUPTA KA, SAXENA AK, JAIN PC, ANAND N. ChemInform Abstract: SYNTHESES AND BIOLOGICAL ACTIVITIES OF 1,4-DISUBSTITUTED PIPERIDINES Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198525238 |
0.555 |
|
| 1985 |
Ram S, Saxena AK, Jain PC, Patnaik GK. Synthesis And Structure-Activity Relationships Of 1-Substituted-Aminomethyl-3-Phenyl/Methyl-1,3-Dihydroisobenzofurans And 4-Substituted-Amino-1-Phenyl/Methylisochromans - A New Class Of Antihistaminics Cheminform. 16. DOI: 10.1002/Chin.198521199 |
0.392 |
|
| 1985 |
Verma M, Gujrati VR, Sharma M, Bhalla TN, Saxena AK, Sinha JN, Bhargava KP, Shanker K. Syntheses And Anti-Inflammatory Activities Of Substituted Arylamino-(N′-Benzylidene)Acetohydrazides And Derivatives Cheminform. 16. DOI: 10.1002/Chin.198507164 |
0.34 |
|
| 1984 |
Verma M, Gujrati VR, Sharma M, Bhalla TN, Saxena AK, Sinha JN, Bhargava KP, Shanker K. Syntheses and Anti‐inflammatory Activities of Substituted Arylamino‐(N′‐benzylidene)acetohydrazides and Derivatives Archiv Der Pharmazie. 317: 890-894. PMID 6393911 DOI: 10.1002/Ardp.19843171015 |
0.369 |
|
| 1984 |
Gupta KA, Saxena AK, Jain PC, Anand N. Syntheses and biological activities of 1,4-disubstituted piperidines. Archiv Der Pharmazie. 317: 1010-7. PMID 6098241 DOI: 10.1002/Ardp.19843171206 |
0.591 |
|
| 1984 |
Saxena AK, Dhaon MK, Ram S, Saxena M, Jain PC, Patnaik GK, Anand N. Synthesis And Qsar In 2-Substituted 1,2,3,4,6,7,12,12A-Octahydropyrazino(2′,1′:6,1)Pyrido(3,4-B)Indoles - A New Class Of H1-Antagonists Cheminform. 15. DOI: 10.1002/Chin.198428254 |
0.597 |
|
| 1984 |
Gupta KA, Saxena AK, Jain PC, Dua PR, Prasad CR, Anand N. Synthesis And Biological Activity Of 2,6-Disubstituted 3-Aryl-4(3H)-Pyrimidinones As Potential Cns Agents Cheminform. 15. DOI: 10.1002/Chin.198403243 |
0.593 |
|
| 1983 |
Gupta KA, Saxena AK, Jain PC, Srimal RC, Kar K, Anand N. Synthesis And Biological Evaluation Of 6-Substituted 3-Aryl-2-Methyl-4(3H)-Pyrimidinones Cheminform. 14. DOI: 10.1002/Chin.198337229 |
0.572 |
|
| 1982 |
Verma M, Gujrati VR, Sharma M, Saxena AK, Bhalla TN, Sinha JN, Bhargava KP, Shanker K. Indolyl compounds as antiinflammatory agents. Archiv Der Pharmazie. 315: 358-363. PMID 7092514 DOI: 10.1002/Ardp.19823150414 |
0.414 |
|
| 1982 |
Agarwal SK, Kumar Y, Saxena AK, Jain PC, Anand N. Synthesis And Biological Activities Of 3-Substituted 1-(Aryloxy)Aminopropanes Cheminform. 13. DOI: 10.1002/Chin.198250353 |
0.609 |
|
| 1982 |
Kumar N, Dhaon MK, Agarwal SK, Saxena AK, Jain PC, Prasad CR, Anand N. Agents Acting On Cns. Part Xxix. Synthesis Of Seco Analogs Of Centbutindole, A Potent Neuroleptic. Cheminform. 13. DOI: 10.1002/Chin.198248377 |
0.585 |
|
| 1982 |
Gupta KA, Saxena AK, Jain PC. Synthesis And Pharmacological Evaluation Of Ethyl 3-Substituted-Phenyl-2-Methylthio/Phenyl/Methyl-4(3H)-Pyrimidone-5-Carboxylates Cheminform. 13. DOI: 10.1002/Chin.198235233 |
0.359 |
|
| 1981 |
Gupta KA, Saxena AK, Jain PC. A Convenient Method for the Synthesis of 2,6-Disubstituted 3-Aryl-4(3H)-pyrimidones Synthesis. 1981: 905-907. DOI: 10.1055/S-1981-29644 |
0.315 |
|
| 1981 |
Agarwal SK, Saxena AK, Anand N. A Convenient Method for IndoleN-Alkylation in Substituted Pyrazino[2′,1′:6,1]pyrido[3,4-b]indoles Synthesis. 1981: 465-466. DOI: 10.1002/Chin.198143220 |
0.558 |
|
| 1981 |
AGARWAL SK, SAXENA AK, ANAND N. ChemInform Abstract: A CONVENIENT METHOD FOR INDOLE N-ALKYLATION IN SUBSTITUTED PYRAZINO(2,1:6,1)PYRIDO(3,4-B)INDOLES Chemischer Informationsdienst. 12. DOI: 10.1002/chin.198143220 |
0.513 |
|
| 1979 |
Saxena AK, Ram S. Quantitative structure-activity relationships Progress in Drug Research. 23: 199-232. PMID 44555 DOI: 10.1007/978-3-0348-7105-1_6 |
0.304 |
|
| 1979 |
Seeman P, Westman K, Protiva M, Jílek J, Jain PC, Saxena AK, Anand N, Humber L, Philipp A. Neuroleptic receptors: Stereoselectivity for neuroleptic enantiomers European Journal of Pharmacology. 56: 247-251. PMID 38971 DOI: 10.1016/0014-2999(79)90177-8 |
0.473 |
|
| 1979 |
Ram S, Saxena AK, Jain PC. 2-Substituted 4-Hydroxy-1,2,3,4-Tetrahydroisoquinolines Cheminform. 10. DOI: 10.1002/Chin.197927249 |
0.369 |
|
| 1975 |
Saxena AK, Jain PC, Anand N. Compounds Acting On The Cns Part 21, Synthesis Of 2-Substituted 1,3,4,6,11,11A-Hexahydro-2(H)Pyrazino (1,2-B)Isoquinoline And Corresponding 8,9-Dimethoxy- And 6-Phenyl-8,9-Dimethoxy Analogs Cheminform. 6. DOI: 10.1002/Chin.197526293 |
0.62 |
|
| 1975 |
Saxena AK, Jain PC, Anand N. Epimerization Of Cis- And Trans-1-Phenyl-1,2,3,4-Tetrahydro-9(H)Pyrido(3,4-B)Indole-3-Carboxylic Acids By Treatment With Acids And Bases Cheminform. 6. DOI: 10.1002/Chin.197504287 |
0.538 |
|
| 1973 |
Saxena AK, Jain PC, Anand N, Dua PR. Compounds Acting On Cns Part 16, Synthesis Of 6-Phenyl- And 6-Methyl-1,2,3,4,6,7,12,12A-Oktahydropyrazino(2′,1′/6,1)Pyrido(3,4-B)Indoles Cheminform. 4. DOI: 10.1002/Chin.197339274 |
0.608 |
|
| 1973 |
SAXENA AK, JAIN PC, ANAND N, DUA PR. ChemInform Abstract: AGENTS ACTING ON THE CENTRAL NERVOUS SYSTEM PART 15, 2-SUBSTITUTED 1,2,3,4,6,7,12,12A-OCTAHYDROPYRAZINO(2′,1′/6,1)PYRIDO(3,4-B)INDOLES, A NEW CLASS OF CENTRAL NERVOUS SYSTEM DEPRESSANTS Chemischer Informationsdienst. 4: no-no. DOI: 10.1002/Chin.197338260 |
0.565 |
|
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