| Year |
Citation |
Score |
| 2023 |
Singh P, Gollapalli K, Mangiola S, Schranner D, Yusuf MA, Chamoli M, Shi SL, Lopes Bastos B, Nair T, Riermeier A, Vayndorf EM, Wu JZ, Nilakhe A, Nguyen CQ, Muir M, ... ... Kaeberlein M, et al. Taurine deficiency as a driver of aging. Science (New York, N.Y.). 380: eabn9257. PMID 37289866 DOI: 10.1126/science.abn9257 |
0.309 |
|
| 2023 |
Phua CZJ, Zhao X, Turcios-Hernandez L, McKernan M, Abyadeh M, Ma S, Promislow D, Kaeberlein M, Kaya A. Genetic perturbation of mitochondrial function reveals functional role for specific mitonuclear genes, metabolites, and pathways that regulate lifespan. Geroscience. PMID 37086368 DOI: 10.1007/s11357-023-00796-4 |
0.313 |
|
| 2021 |
Bitto A, Lee MB, Hill CM, Korstanje R, Kaeberlein M. The AGE Presents Introduction to Geroscience video lecture series. Geroscience. PMID 34129171 DOI: 10.1007/s11357-021-00403-4 |
0.574 |
|
| 2021 |
Bitto A, Lee MB, Hill CM, Korstanje R, Kaeberlein M. The AGE Presents Introduction to Geroscience video lecture series. Geroscience. PMID 34129171 DOI: 10.1007/s11357-021-00403-4 |
0.574 |
|
| 2021 |
Berry BJ, Kaeberlein M. An energetics perspective on geroscience: mitochondrial protonmotive force and aging. Geroscience. PMID 33864592 DOI: 10.1007/s11357-021-00365-7 |
0.318 |
|
| 2020 |
Mouton SN, Thaller DJ, Crane MM, Rempel IL, Terpstra OT, Steen A, Kaeberlein M, Lusk CP, Boersma AJ, Veenhoff LM. A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast. Elife. 9. PMID 32990592 DOI: 10.7554/eLife.54707 |
0.326 |
|
| 2019 |
Crane MM, Tsuchiya M, Blue BW, Almazan JD, Chen KL, Duffy SR, Golubeva A, Grimm AM, Guard AM, Hill SA, Huynh E, Kelly RM, Kiflezghi M, Kim HD, Lee M, ... ... Kaeberlein M, et al. Rb analog Whi5 regulates G1 to S transition and cell size but not replicative lifespan in budding yeast. Translational Medicine of Aging. 3: 104-108. PMID 32190787 DOI: 10.1016/J.Tma.2019.10.002 |
0.316 |
|
| 2019 |
Crane MM, Russell AE, Schafer BJ, Blue BW, Whalen R, Almazan J, Hong MG, Nguyen B, Goings JE, Chen KL, Kelly R, Kaeberlein M. DNA damage checkpoint activation impairs chromatin homeostasis and promotes mitotic catastrophe during aging. Elife. 8. PMID 31714209 DOI: 10.7554/Elife.50778 |
0.312 |
|
| 2019 |
Crane MM, Chen KL, Blue BW, Kaeberlein M. Trajectories of Aging: How Systems Biology in Yeast can Illuminate Mechanisms of Personalized Aging. Proteomics. e1800420. PMID 31385433 DOI: 10.1002/Pmic.201800420 |
0.314 |
|
| 2019 |
Rempel IL, Crane MM, Thaller DJ, Mishra A, Jansen DP, Janssens G, Popken P, Akşit A, Kaeberlein M, van der Giessen E, Steen A, Onck PR, Lusk CP, Veenhoff LM. Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics. Elife. 8. PMID 31157618 DOI: 10.7554/Elife.48186 |
0.341 |
|
| 2018 |
Crane MM, Kaeberlein M. The paths of mortality: how understanding the biology of aging can help explain systems behavior of single cells. Current Opinion in Systems Biology. 8: 25-31. PMID 29552673 DOI: 10.1016/J.Coisb.2017.11.010 |
0.341 |
|
| 2017 |
Miller H, Fletcher M, Primitivo M, Leonard A, Sutphin GL, Rintala N, Kaeberlein M, Leiser SF. Genetic interaction with temperature is an important determinant of nematode longevity. Aging Cell. PMID 28940623 DOI: 10.1111/acel.12658 |
0.784 |
|
| 2017 |
Rossner R, Kaeberlein M, Leiser SF. Flavin-containing monooxygenases in aging and disease: Emerging roles for ancient enzymes. The Journal of Biological Chemistry. 292: 11138-11146. PMID 28515321 DOI: 10.1074/jbc.R117.779678 |
0.748 |
|
| 2017 |
Mendenhall A, Crane MM, Leiser S, Sutphin G, Tedesco PM, Kaeberlein M, Johnson TE, Brent R. Environmental Canalization of Life Span and Gene Expression in Caenorhabditis elegans. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 28369388 DOI: 10.1093/Gerona/Glx017 |
0.783 |
|
| 2016 |
Leiser SF, Jafari G, Primitivo M, Sutphin GL, Dong J, Leonard A, Fletcher M, Kaeberlein M. Age-associated vulval integrity is an important marker of nematode healthspan. Age (Dordrecht, Netherlands). PMID 27566309 DOI: 10.1007/s11357-016-9936-8 |
0.8 |
|
| 2016 |
Leiser SF, Rossner R, Kaeberlein M. New insights into cell non-autonomous mechanisms of the C. elegans hypoxic response. Worm. 5: e1176823. PMID 27383456 DOI: 10.1080/21624054.2016.1176823 |
0.737 |
|
| 2015 |
Kaya A, Ma S, Wasko B, Lee M, Kaeberlein M, Gladyshev VN. Defining Molecular Basis for Longevity Traits in Natural Yeast Isolates. Npj Aging and Mechanisms of Disease. 1. PMID 27030810 DOI: 10.1038/npjamd.2015.1 |
0.311 |
|
| 2015 |
Kaeberlein M, Rabinovitch PS, Martin GM. Healthy aging: The ultimate preventative medicine Science. 350: 1191-1193. PMID 26785476 DOI: 10.1126/Science.Aad3267 |
0.313 |
|
| 2015 |
Leiser SF, Miller H, Rossner R, Fletcher M, Leonard A, Primitivo M, Rintala N, Ramos FJ, Miller DL, Kaeberlein M. Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span. Science (New York, N.Y.). PMID 26586189 DOI: 10.1126/Science.Aac9257 |
0.741 |
|
| 2015 |
Chandler-Brown D, Choi H, Park S, Ocampo BR, Chen S, Le A, Sutphin GL, Shamieh LS, Smith ED, Kaeberlein M. Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans. Frontiers in Genetics. 6: 316. PMID 26579191 DOI: 10.3389/fgene.2015.00316 |
0.706 |
|
| 2015 |
Bitto A, Wang AM, Bennett CF, Kaeberlein M. Biochemical Genetic Pathways that Modulate Aging in Multiple Species. Cold Spring Harbor Perspectives in Medicine. 5. PMID 26525455 DOI: 10.1101/Cshperspect.A025114 |
0.349 |
|
| 2015 |
Vermulst M, Denney AS, Lang MJ, Hung CW, Moore S, Moseley MA, Thompson JW, Madden V, Gauer J, Wolfe KJ, Summers DW, Schleit J, Sutphin GL, Haroon S, Holczbauer A, ... ... Kaeberlein M, et al. Corrigendum: Transcription errors induce proteotoxic stress and shorten cellular lifespan. Nature Communications. 6: 8738. PMID 26465398 DOI: 10.1038/Ncomms9738 |
0.75 |
|
| 2015 |
McCormick MA, Delaney JR, Tsuchiya M, Tsuchiyama S, Shemorry A, Sim S, Chou AC, Ahmed U, Carr D, Murakami CJ, Schleit J, Sutphin GL, Wasko BM, Bennett CF, Wang AM, ... ... Kaeberlein M, et al. A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. Cell Metabolism. PMID 26456335 DOI: 10.1016/J.Cmet.2015.09.008 |
0.794 |
|
| 2015 |
Yang J, McCormick MA, Zheng J, Xie Z, Tsuchiya M, Tsuchiyama S, El-Samad H, Ouyang Q, Kaeberlein M, Kennedy BK, Li H. Systematic analysis of asymmetric partitioning of yeast proteome between mother and daughter cells reveals "aging factors" and mechanism of lifespan asymmetry. Proceedings of the National Academy of Sciences of the United States of America. 112: 11977-82. PMID 26351681 DOI: 10.1073/Pnas.1506054112 |
0.316 |
|
| 2015 |
Vermulst M, Denney AS, Lang MJ, Hung CW, Moore S, Mosely AM, Thompson WJ, Madden V, Gauer J, Wolfe KJ, Summers DW, Schleit J, Sutphin GL, Haroon S, Holczbauer A, ... ... Kaeberlein M, et al. Transcription errors induce proteotoxic stress and shorten cellular lifespan. Nature Communications. 6: 8065. PMID 26304740 DOI: 10.1038/Ncomms9065 |
0.788 |
|
| 2015 |
Johnson SC, Yanos ME, Bitto A, Castanza A, Gagnidze A, Gonzalez B, Gupta K, Hui J, Jarvie C, Johnson BM, Letexier N, McCanta L, Sangesland M, Tamis O, Uhde L, ... ... Kaeberlein M, et al. Dose-dependent effects of mTOR inhibition on weight and mitochondrial disease in mice. Frontiers in Genetics. 6: 247. PMID 26257774 DOI: 10.3389/Fgene.2015.00247 |
0.763 |
|
| 2015 |
Sen P, Dang W, Donahue G, Dai J, Dorsey J, Cao X, Liu W, Cao K, Perry R, Lee JY, Wasko BM, Carr DT, He C, Robison B, Wagner J, ... ... Kaeberlein M, et al. H3K36 methylation promotes longevity by enhancing transcriptional fidelity. Genes & Development. 29: 1362-1376. PMID 26159996 DOI: 10.1101/Gad.263707.115 |
0.56 |
|
| 2015 |
Cui HJ, Liu XG, McCormick M, Wasko BM, Zhao W, He X, Yuan Y, Fang BX, Sun XR, Kennedy BK, Suh Y, Zhou ZJ, Kaeberlein M, Feng WL. PMT1 deficiency enhances basal UPR activity and extends replicative lifespan of Saccharomyces cerevisiae. Age (Dordrecht, Netherlands). 37: 9788. PMID 25936926 DOI: 10.1007/S11357-015-9788-7 |
0.334 |
|
| 2015 |
Pitt JN, Kaeberlein M. Why is aging conserved and what can we do about it? Plos Biology. 13: e1002131. PMID 25923592 DOI: 10.1371/journal.pbio.1002131 |
0.316 |
|
| 2015 |
Johnson SC, Sangesland M, Kaeberlein M, Rabinovitch PS. Modulating mTOR in aging and health. Interdisciplinary Topics in Gerontology. 40: 107-27. PMID 25341517 DOI: 10.1159/000364974 |
0.329 |
|
| 2014 |
He C, Tsuchiyama SK, Nguyen QT, Plyusnina EN, Terrill SR, Sahibzada S, Patel B, Faulkner AR, Shaposhnikov MV, Tian R, Tsuchiya M, Kaeberlein M, Moskalev AA, Kennedy BK, Polymenis M. Enhanced longevity by ibuprofen, conserved in multiple species, occurs in yeast through inhibition of tryptophan import. Plos Genetics. 10: e1004860. PMID 25521617 DOI: 10.1371/Journal.Pgen.1004860 |
0.327 |
|
| 2014 |
Sutphin GL, Delaney JR, Kaeberlein M. Replicative life span analysis in budding yeast Methods in Molecular Biology. 1205: 341-357. PMID 25213254 DOI: 10.1007/978-1-4939-1363-3_20 |
0.735 |
|
| 2014 |
McCormick MA, Mason AG, Guyenet SJ, Dang W, Garza RM, Ting MK, Moller RM, Berger SL, Kaeberlein M, Pillus L, La Spada AR, Kennedy BK. The SAGA histone deubiquitinase module controls yeast replicative lifespan via Sir2 interaction. Cell Reports. 8: 477-86. PMID 25043177 DOI: 10.1016/J.Celrep.2014.06.037 |
0.524 |
|
| 2014 |
Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, ... ... Kaeberlein M, et al. Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response. Cell Metabolism. 19: 952-66. PMID 24814484 DOI: 10.1016/J.Cmet.2014.04.004 |
0.757 |
|
| 2014 |
Wasko BM, Kaeberlein M. Yeast replicative aging: a paradigm for defining conserved longevity interventions. Fems Yeast Research. 14: 148-59. PMID 24119093 DOI: 10.1111/1567-1364.12104 |
0.348 |
|
| 2013 |
Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, ... ... Kaeberlein M, et al. mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome. Science (New York, N.Y.). 342: 1524-8. PMID 24231806 DOI: 10.1126/Science.1244360 |
0.774 |
|
| 2013 |
Kaeberlein M. Deciphering the role of natural variation in age-related protein homeostasis. Bmc Biology. 11: 102. PMID 24228595 DOI: 10.1186/1741-7007-11-102 |
0.321 |
|
| 2013 |
Schleit J, Johnson SC, Bennett CF, Simko M, Trongtham N, Castanza A, Hsieh EJ, Moller RM, Wasko BM, Delaney JR, Sutphin GL, Carr D, Murakami CJ, Tocchi A, Xian B, ... ... Kaeberlein M, et al. Molecular mechanisms underlying genotype-dependent responses to dietary restriction. Aging Cell. 12: 1050-61. PMID 23837470 DOI: 10.1111/Acel.12130 |
0.791 |
|
| 2013 |
Kaeberlein M. Longevity and aging. F1000prime Reports. 5: 5. PMID 23513177 DOI: 10.12703/P5-5 |
0.346 |
|
| 2013 |
Leiser SF, Fletcher M, Begun A, Kaeberlein M. Life-span extension from hypoxia in Caenorhabditis elegans requires both HIF-1 and DAF-16 and is antagonized by SKN-1. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 68: 1135-44. PMID 23419779 DOI: 10.1093/gerona/glt016 |
0.752 |
|
| 2013 |
Delaney JR, Chou A, Olsen B, Carr D, Murakami C, Ahmed U, Sim S, An EH, Castanza AS, Fletcher M, Higgins S, Holmberg M, Hui J, Jelic M, Jeong KS, ... ... Kaeberlein M, et al. End-of-life cell cycle arrest contributes to stochasticity of yeast replicative aging. Fems Yeast Research. 13: 267-76. PMID 23336757 DOI: 10.1111/1567-1364.12030 |
0.776 |
|
| 2013 |
Johnson SC, Rabinovitch PS, Kaeberlein M. mTOR is a key modulator of ageing and age-related disease. Nature. 493: 338-45. PMID 23325216 DOI: 10.1038/Nature11861 |
0.318 |
|
| 2013 |
Delaney JR, Murakami C, Chou A, Carr D, Schleit J, Sutphin GL, An EH, Castanza AS, Fletcher M, Goswami S, Higgins S, Holmberg M, Hui J, Jelic M, Jeong KS, ... ... Kaeberlein M, et al. Dietary restriction and mitochondrial function link replicative and chronological aging in Saccharomyces cerevisiae. Experimental Gerontology. 48: 1006-13. PMID 23235143 DOI: 10.1016/J.Exger.2012.12.001 |
0.799 |
|
| 2013 |
Delaney JR, Ahmed U, Chou A, Sim S, Carr D, Murakami CJ, Schleit J, Sutphin GL, An EH, Castanza A, Fletcher M, Higgins S, Jelic M, Klum S, Muller B, ... ... Kaeberlein M, et al. Stress profiling of longevity mutants identifies Afg3 as a mitochondrial determinant of cytoplasmic mRNA translation and aging. Aging Cell. 12: 156-66. PMID 23167605 DOI: 10.1111/Acel.12032 |
0.784 |
|
| 2012 |
Sutphin GL, Bishop E, Yanos ME, Moller RM, Kaeberlein M. Caffeine extends life span, improves healthspan, and delays age-associated pathology in Caenorhabditis elegans. Longevity & Healthspan. 1: 9. PMID 24764514 DOI: 10.1186/2046-2395-1-9 |
0.727 |
|
| 2012 |
Murakami C, Delaney JR, Chou A, Carr D, Schleit J, Sutphin GL, An EH, Castanza AS, Fletcher M, Goswami S, Higgins S, Holmberg M, Hui J, Jelic M, Jeong KS, ... ... Kaeberlein M, et al. pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast. Cell Cycle (Georgetown, Tex.). 11: 3087-96. PMID 22871733 DOI: 10.4161/Cc.21465 |
0.787 |
|
| 2012 |
Schleit J, Wasko BM, Kaeberlein M. Yeast as a model to understand the interaction between genotype and the response to calorie restriction. Febs Letters. 586: 2868-73. PMID 22828279 DOI: 10.1016/j.febslet.2012.07.038 |
0.758 |
|
| 2012 |
Longo VD, Shadel GS, Kaeberlein M, Kennedy B. Replicative and chronological aging in Saccharomyces cerevisiae. Cell Metabolism. 16: 18-31. PMID 22768836 DOI: 10.1016/J.Cmet.2012.06.002 |
0.372 |
|
| 2012 |
Zhou B, Yang L, Li S, Huang J, Chen H, Hou L, Wang J, Green CD, Yan Z, Huang X, Kaeberlein M, Zhu L, Xiao H, Liu Y, Han JD. Midlife gene expressions identify modulators of aging through dietary interventions. Proceedings of the National Academy of Sciences of the United States of America. 109: E1201-9. PMID 22509016 DOI: 10.1073/Pnas.1119304109 |
0.337 |
|
| 2012 |
Sutphin GL, Olsen BA, Kennedy BK, Kaeberlein M. Genome-wide analysis of yeast aging. Sub-Cellular Biochemistry. 57: 251-89. PMID 22094426 DOI: 10.1007/978-94-007-2561-4_12 |
0.712 |
|
| 2011 |
Schleit J, Wall VZ, Simko M, Kaeberlein M. The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans. Plos One. 6: e28036. PMID 22132200 DOI: 10.1371/journal.pone.0028036 |
0.762 |
|
| 2011 |
Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, ... ... Kaeberlein M, et al. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature. 477: 482-5. PMID 21938067 DOI: 10.1038/Nature10296 |
0.72 |
|
| 2011 |
Kruegel U, Robison B, Dange T, Kahlert G, Delaney JR, Kotireddy S, Tsuchiya M, Tsuchiyama S, Murakami CJ, Schleit J, Sutphin G, Carr D, Tar K, Dittmar G, Kaeberlein M, et al. Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae. Plos Genetics. 7: e1002253. PMID 21931558 DOI: 10.1371/Journal.Pgen.1002253 |
0.822 |
|
| 2011 |
Delaney JR, Sutphin GL, Dulken B, Sim S, Kim JR, Robison B, Schleit J, Murakami CJ, Carr D, An EH, Choi E, Chou A, Fletcher M, Jelic M, Liu B, ... ... Kaeberlein M, et al. Sir2 deletion prevents lifespan extension in 32 long-lived mutants. Aging Cell. 10: 1089-91. PMID 21902802 DOI: 10.1111/J.1474-9726.2011.00742.X |
0.796 |
|
| 2011 |
Kaeberlein M, Kennedy BK, Liu X, Suh Y, Zhou Z. Trinations aging symposium. Mechanisms of Ageing and Development. 132: 348-52. PMID 21771608 DOI: 10.1016/J.Mad.2011.07.001 |
0.316 |
|
| 2011 |
Burtner CR, Murakami CJ, Olsen B, Kennedy BK, Kaeberlein M. A genomic analysis of chronological longevity factors in budding yeast. Cell Cycle (Georgetown, Tex.). 10: 1385-96. PMID 21447998 DOI: 10.4161/Cc.10.9.15464 |
0.356 |
|
| 2011 |
Leiser SF, Begun A, Kaeberlein M. HIF-1 modulates longevity and healthspan in a temperature-dependent manner. Aging Cell. 10: 318-26. PMID 21241450 DOI: 10.1111/j.1474-9726.2011.00672.x |
0.766 |
|
| 2011 |
Leiser SF, Kaeberlein M. The hypoxia-inducible factor HIF-1 functions as both a positive and negative modulator of aging. Biological Chemistry. 391: 1131-7. PMID 20707608 DOI: 10.1515/bc.2010.123 |
0.765 |
|
| 2011 |
Kaeberlein M. Longevity genomics across species. Current Genomics. 8: 73-8. PMID 18660849 DOI: 10.2174/138920207780368196 |
0.333 |
|
| 2010 |
Leiser SF, Kaeberlein M. A role for SIRT1 in the hypoxic response. Molecular Cell. 38: 779-80. PMID 20620950 DOI: 10.1016/j.molcel.2010.06.015 |
0.737 |
|
| 2010 |
Kaeberlein M. Lessons on longevity from budding yeast. Nature. 464: 513-9. PMID 20336133 DOI: 10.1038/nature08981 |
0.321 |
|
| 2009 |
Kaeberlein M, Kapahi P. Cell signaling. Aging is RSKy business. Science (New York, N.Y.). 326: 55-6. PMID 19797648 DOI: 10.1126/Science.1181034 |
0.352 |
|
| 2009 |
Steffen KK, Kennedy BK, Kaeberlein M. Measuring replicative life span in the budding yeast. Journal of Visualized Experiments : Jove. PMID 19556967 DOI: 10.3791/1209 |
0.35 |
|
| 2009 |
Stanfel MN, Shamieh LS, Kaeberlein M, Kennedy BK. The TOR pathway comes of age. Biochimica Et Biophysica Acta. 1790: 1067-74. PMID 19539012 DOI: 10.1016/J.Bbagen.2009.06.007 |
0.303 |
|
| 2009 |
Burtner CR, Murakami CJ, Kaeberlein M. A genomic approach to yeast chronological aging. Methods in Molecular Biology (Clifton, N.J.). 548: 101-14. PMID 19521821 DOI: 10.1007/978-1-59745-540-4_6 |
0.32 |
|
| 2009 |
Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL. Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature. 459: 802-7. PMID 19516333 DOI: 10.1038/Nature08085 |
0.505 |
|
| 2009 |
Sutphin GL, Kaeberlein M. Measuring Caenorhabditis elegans life span on solid media. Journal of Visualized Experiments : Jove. PMID 19488025 DOI: 10.3791/1152 |
0.72 |
|
| 2009 |
Murakami C, Kaeberlein M. Quantifying yeast chronological life span by outgrowth of aged cells. Journal of Visualized Experiments. PMID 19421136 DOI: 10.3791/1156 |
0.364 |
|
| 2009 |
Mehta R, Steinkraus KA, Sutphin GL, Ramos FJ, Shamieh LS, Huh A, Davis C, Chandler-Brown D, Kaeberlein M. Proteasomal regulation of the hypoxic response modulates aging in C. elegans. Science (New York, N.Y.). 324: 1196-8. PMID 19372390 DOI: 10.1126/science.1173507 |
0.721 |
|
| 2009 |
Burtner CR, Murakami CJ, Kennedy BK, Kaeberlein M. A molecular mechanism of chronological aging in yeast. Cell Cycle (Georgetown, Tex.). 8: 1256-70. PMID 19305133 DOI: 10.4161/Cc.8.8.8287 |
0.372 |
|
| 2009 |
Steffen KK, Kennedy BK, Kaeberlein M. Measuring replicative life span in the budding yeast Journal of Visualized Experiments. DOI: 10.3791/1209 |
0.349 |
|
| 2008 |
Steinkraus KA, Kaeberlein M, Kennedy BK. Replicative aging in yeast: the means to the end. Annual Review of Cell and Developmental Biology. 24: 29-54. PMID 18616424 DOI: 10.1146/Annurev.Cellbio.23.090506.123509 |
0.371 |
|
| 2008 |
Steffen KK, MacKay VL, Kerr EO, Tsuchiya M, Hu D, Fox LA, Dang N, Johnston ED, Oakes JA, Tchao BN, Pak DN, Fields S, Kennedy BK, Kaeberlein M. Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4. Cell. 133: 292-302. PMID 18423200 DOI: 10.1016/J.Cell.2008.02.037 |
0.582 |
|
| 2008 |
Smith ED, Tsuchiya M, Fox LA, Dang N, Hu D, Kerr EO, Johnston ED, Tchao BN, Pak DN, Welton KL, Promislow DE, Thomas JH, Kaeberlein M, Kennedy BK. Quantitative evidence for conserved longevity pathways between divergent eukaryotic species. Genome Research. 18: 564-70. PMID 18340043 DOI: 10.1101/Gr.074724.107 |
0.356 |
|
| 2008 |
Steinkraus KA, Smith ED, Davis C, Carr D, Pendergrass WR, Sutphin GL, Kennedy BK, Kaeberlein M. Dietary restriction suppresses proteotoxicity and enhances longevity by an hsf-1-dependent mechanism in Caenorhabditis elegans. Aging Cell. 7: 394-404. PMID 18331616 DOI: 10.1111/J.1474-9726.2008.00385.X |
0.714 |
|
| 2008 |
Murakami CJ, Burtner CR, Kennedy BK, Kaeberlein M. A method for high-throughput quantitative analysis of yeast chronological life span. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 63: 113-21. PMID 18314444 DOI: 10.1093/Gerona/63.2.113 |
0.302 |
|
| 2008 |
Sutphin GL, Kaeberlein M. Dietary restriction by bacterial deprivation increases life span in wild-derived nematodes. Experimental Gerontology. 43: 130-5. PMID 18083317 DOI: 10.1016/j.exger.2007.10.019 |
0.693 |
|
| 2007 |
Kaeberlein M, Burtner CR, Kennedy BK. Recent Developments in Yeast Aging Plos Genetics. 3. PMID 17530929 DOI: 10.1371/Journal.Pgen.0030084 |
0.34 |
|
| 2007 |
Kaeberlein M, Powers RW. Sir2 and calorie restriction in yeast: a skeptical perspective. Ageing Research Reviews. 6: 128-40. PMID 17512264 DOI: 10.1016/j.arr.2007.04.001 |
0.582 |
|
| 2007 |
Kennedy BK, Steffen KK, Kaeberlein M. Ruminations on dietary restriction and aging. Cellular and Molecular Life Sciences. 64: 1323-1328. PMID 17396225 DOI: 10.1007/S00018-007-6470-Y |
0.331 |
|
| 2007 |
Smith ED, Kennedy BK, Kaeberlein M. Genome-wide identification of conserved longevity genes in yeast and worms. Mechanisms of Ageing and Development. 128: 106-11. PMID 17126379 DOI: 10.1016/J.Mad.2006.11.017 |
0.324 |
|
| 2006 |
Kaeberlein TL, Smith ED, Tsuchiya M, Welton KL, Thomas JH, Fields S, Kennedy BK, Kaeberlein M. Lifespan extension in Caenorhabditis elegans by complete removal of food. Aging Cell. 5: 487-94. PMID 17081160 DOI: 10.1111/J.1474-9726.2006.00238.X |
0.457 |
|
| 2006 |
Kaeberlein M. Genome-wide approaches to understanding human ageing. Human Genomics. 2: 422-8. PMID 16848980 DOI: 10.1186/1479-7364-2-6-422 |
0.325 |
|
| 2006 |
Kaeberlein M, Steffen KK, Hu D, Dang N, Kerr EO, Tsuchiya M, Fields S, Kennedy BK. Comment on "HST2 mediates SIR2-independent life-span extension by calorie restriction". Science (New York, N.Y.). 312: 1312; author reply 1. PMID 16741098 DOI: 10.1126/Science.1124608 |
0.482 |
|
| 2006 |
Powers RW, Kaeberlein M, Caldwell SD, Kennedy BK, Fields S. Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes & Development. 20: 174-84. PMID 16418483 DOI: 10.1101/Gad.1381406 |
0.728 |
|
| 2005 |
Kaeberlein M, Hu D, Kerr EO, Tsuchiya M, Westman EA, Dang N, Fields S, Kennedy BK. Increased life span due to calorie restriction in respiratory-deficient yeast. Plos Genetics. 1: e69. PMID 16311627 DOI: 10.1371/Journal.Pgen.0010069 |
0.537 |
|
| 2005 |
Kaeberlein M, Powers RW, Steffen KK, Westman EA, Hu D, Dang N, Kerr EO, Kirkland KT, Fields S, Kennedy BK. Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science (New York, N.Y.). 310: 1193-6. PMID 16293764 DOI: 10.1126/Science.1115535 |
0.728 |
|
| 2005 |
Kaeberlein M, Kirkland KT, Fields S, Kennedy BK. Genes determining yeast replicative life span in a long-lived genetic background. Mechanisms of Ageing and Development. 126: 491-504. PMID 15722108 DOI: 10.1016/J.Mad.2004.10.007 |
0.593 |
|
| 2005 |
Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, Kennedy BK. Substrate-specific activation of sirtuins by resveratrol. The Journal of Biological Chemistry. 280: 17038-45. PMID 15684413 DOI: 10.1074/Jbc.M500655200 |
0.517 |
|
| 2005 |
Kaeberlein M, Kennedy BK. Large-scale identification in yeast of conserved ageing genes Mechanisms of Ageing and Development. 126: 17-21. PMID 15610758 DOI: 10.1016/J.Mad.2004.09.013 |
0.344 |
|
| 2004 |
Kaeberlein M, Kirkland KT, Fields S, Kennedy BK. Sir2-independent life span extension by calorie restriction in yeast. Plos Biology. 2: E296. PMID 15328540 DOI: 10.1371/Journal.Pbio.0020296 |
0.631 |
|
| 2004 |
Kaeberlein M, Andalis AA, Liszt GB, Fink GR, Guarente L. Saccharomyces cerevisiae SSD1-V confers longevity by a Sir2p-independent mechanism. Genetics. 166: 1661-72. PMID 15126388 DOI: 10.1534/Genetics.166.4.1661 |
0.538 |
|
| 2002 |
Kaeberlein M, Andalis AA, Fink GR, Guarente L. High osmolarity extends life span in Saccharomyces cerevisiae by a mechanism related to calorie restriction. Molecular and Cellular Biology. 22: 8056-66. PMID 12391171 DOI: 10.1128/Mcb.22.22.8056-8066.2002 |
0.562 |
|
| 2002 |
Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, Guarente L. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature. 418: 344-8. PMID 12124627 DOI: 10.1038/Nature00829 |
0.488 |
|
| 2002 |
Kaeberlein M, Jegalian B, McVey M. AGEID: a database of aging genes and interventions. Mechanisms of Ageing and Development. 123: 1115-9. PMID 12044961 DOI: 10.1016/S0047-6374(02)00011-8 |
0.324 |
|
| 2002 |
Armstrong CM, Kaeberlein M, Imai SI, Guarente L. Mutations in Saccharomyces cerevisiae gene SIR2 can have differential effects on in vivo silencing phenotypes and in vitro histone deacetylation activity. Molecular Biology of the Cell. 13: 1427-38. PMID 11950950 DOI: 10.1091/Mbc.01-10-0482 |
0.46 |
|
| 2002 |
Kaeberlein M, Guarente L. Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity Genetics. 160: 83-95. PMID 11805047 |
0.522 |
|
| 2001 |
Kaeberlein M, McVey M, Guarente L. Using yeast to discover the fountain of youth. Science of Aging Knowledge Environment : Sage Ke. 2001: pe1. PMID 14602950 DOI: 10.1126/Sageke.2001.1.Pe1 |
0.594 |
|
| 2000 |
Imai S, Armstrong CM, Kaeberlein M, Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature. 403: 795-800. PMID 10693811 DOI: 10.1038/35001622 |
0.465 |
|
| 1999 |
Kaeberlein M, McVey M, Guarente L. The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes & Development. 13: 2570-80. PMID 10521401 DOI: 10.1101/Gad.13.19.2570 |
0.577 |
|
| 1999 |
Defossez PA, Prusty R, Kaeberlein M, Lin SJ, Ferrigno P, Silver PA, Keil RL, Guarente L. Elimination of replication block protein Fob1 extends the life span of yeast mother cells Molecular Cell. 3: 447-455. PMID 10230397 DOI: 10.1016/S1097-2765(00)80472-4 |
0.589 |
|
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