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Darin E. Jones - Publications

Affiliations: 
University of Arkansas for Medical Sciences, United States 
Area:
Medicinal chemistry, drug discovery, organic chemistry
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46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shrum SA, Nukala U, Shrimali S, Pineda EN, Krager KJ, Thakkar S, Jones DE, Pathak R, Breen PJ, Aykin-Burns N, Compadre CM. Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects. Antioxidants (Basel, Switzerland). 12. PMID 38001840 DOI: 10.3390/antiox12111987  0.705
2023 Syed A, Filandr F, Patterson-Fortin J, Bacolla A, Ravindranathan R, Zhou J, McDonald DT, Albuhluli ME, Verway-Cohen A, Newman JA, Tsai MS, Jones DE, Schriemer DC, D'Andrea AD, Tainer JA. Novobiocin blocks nucleic acid binding to Polθ and inhibits stimulation of its ATPase activity. Nucleic Acids Research. PMID 37665033 DOI: 10.1093/nar/gkad727  0.733
2022 Brosey CA, Shen R, Moiani D, Jones DE, Burnett K, Hura GL, Tainer JA. Applying HT-SAXS to chemical ligand screening. Methods in Enzymology. 678: 331-350. PMID 36641213 DOI: 10.1016/bs.mie.2022.09.022  0.722
2022 Mery DE, Compadre AJ, Ordóñez PE, Selvik EJ, Morocho V, Contreras J, Malagón O, Jones DE, Breen PJ, Balick MJ, Gaudio FG, Guzman ML, Compadre CM. Analysis of Plant-Plant Interactions Reveals the Presence of Potent Antileukemic Compounds. Molecules (Basel, Switzerland). 27. PMID 35566279 DOI: 10.3390/molecules27092928  0.722
2021 Moiani D, Link TM, Brosey CA, Katsonis P, Lichtarge O, Kim Y, Joachimiak A, Ma Z, Kim IK, Ahmed Z, Jones DE, Tsutakawa SE, Tainer JA. An efficient chemical screening method for structure-based inhibitors to nucleic acid enzymes targeting the DNA repair-replication interface and SARS CoV-2. Methods in Enzymology. 661: 407-431. PMID 34776222 DOI: 10.1016/bs.mie.2021.09.003  0.744
2021 Ye Z, Xu S, Shi Y, Bacolla A, Syed A, Moiani D, Tsai CL, Shen Q, Peng G, Leonard PG, Jones DE, Wang B, Tainer JA, Ahmed Z. GRB2 enforces homology-directed repair initiation by MRE11. Science Advances. 7. PMID 34348893 DOI: 10.1126/sciadv.abe9254  0.73
2021 Nguyen MT, Moiani D, Ahmed Z, Arvai AS, Namjoshi S, Shin DS, Fedorov Y, Selvik EJ, Jones DE, Pink J, Yan Y, Laverty DJ, Nagel ZD, Tainer JA, Gerson SL. An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation. Progress in Biophysics and Molecular Biology. PMID 33675849 DOI: 10.1016/j.pbiomolbio.2021.02.004  0.733
2021 Brosey CA, Houl JH, Katsonis P, Balapiti-Modarage LPF, Bommagani S, Arvai A, Moiani D, Bacolla A, Link T, Warden LS, Lichtarge O, Jones DE, Ahmed Z, Tainer JA. Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors. Progress in Biophysics and Molecular Biology. PMID 33636189 DOI: 10.1016/j.pbiomolbio.2021.02.002  0.746
2020 Ordóñez PE, Mery DE, Sharma KK, Nemu S, Reynolds WF, Enriquez RG, Burns DC, Malagón O, Jones DE, Guzman ML, Compadre CM. Synthesis, Crystallography, and Anti-Leukemic Activity of the Amino Adducts of Dehydroleucodine. Molecules (Basel, Switzerland). 25. PMID 33092263 DOI: 10.3390/molecules25204825  0.742
2019 Houl JH, Ye Z, Brosey CA, Balapiti-Modarage LPF, Namjoshi S, Bacolla A, Laverty D, Walker BL, Pourfarjam Y, Warden LS, Babu Chinnam N, Moiani D, Stegeman RA, Chen MK, Hung MC, ... ... Jones DE, et al. Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death. Nature Communications. 10: 5654. PMID 31827085 DOI: 10.1038/S41467-019-13508-4  0.74
2017 Howes TRL, Sallmyr A, Brooks R, Greco GE, Jones DE, Matsumoto Y, Tomkinson AE. Erratum to "Structure-activity relationships among DNA ligase inhibitors; characterization of a selective uncompetitive DNA ligase I inhibitor" [DNA Repair 60C (2017) 29-39]. Dna Repair. PMID 29273192 DOI: 10.1016/J.Dnarep.2017.12.001  0.729
2017 Howes TRL, Sallymr A, Brooks R, Greco GE, Jones DE, Matsumoto Y, Tomkinson AE. Structure-activity relationships among DNA ligase inhibitors: Characterization of a selective uncompetitive DNA ligase I inhibitor. Dna Repair. 60: 29-39. PMID 29078112 DOI: 10.1016/J.Dnarep.2017.10.002  0.744
2016 Ordóñez PE, Sharma KK, Bystrom LM, Alas MA, Enriquez RG, Malagón O, Jones DE, Guzman ML, Compadre CM. Dehydroleucodine, a Sesquiterpene Lactone from Gynoxys verrucosa, Demonstrates Cytotoxic Activity against Human Leukemia Cells. Journal of Natural Products. PMID 27057812 DOI: 10.1021/Acs.Jnatprod.5B00383  0.728
2015 Franco FM, Jones DE, Harris PK, Han Z, Wildman SA, Jarvis CM, Janetka JW. Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets. Bioorganic & Medicinal Chemistry. 23: 2328-43. PMID 25882520 DOI: 10.1016/J.Bmc.2015.03.072  0.75
2014 Han Z, Harris PK, Jones DE, Chugani R, Kim T, Agarwal M, Shen W, Wildman SA, Janetka JW. Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer. Acs Medicinal Chemistry Letters. 5: 1219-24. PMID 25408834 DOI: 10.1021/Ml500254R  0.746
2014 Gartia Y, Ramidi P, Cheerla S, Felton CM, Jones DE, Das BC, Ghosh A. Activation of sp3 and sp2 C-H bonds of oxygen containing heterocyclic molecules for alkylation and arylation reactions catalyzed by an iron complex Journal of Molecular Catalysis a: Chemical. 392: 253-259. DOI: 10.1016/J.Molcata.2014.05.013  0.737
2014 Gartia Y, Ramidi P, Jones DE, Pulla S, Ghosh A. Nickel complex catalyzed efficient activation of sp3and sp 2c-h bonds for alkylation and arylation of oxygen containing heterocyclic molecules Catalysis Letters. 144: 507-515. DOI: 10.1007/S10562-013-1170-8  0.762
2014 Jones DE, Harmata M. Application of The [4+3] Cycloaddition Reaction To The Synthesis of Natural Products Methods and Applications of Cycloaddition Reactions in Organic Syntheses. 599-630. DOI: 10.1002/9781118778173.ch19  0.651
2013 Arhancet GB, Walker DP, Metz S, Fobian YM, Heasley SE, Carter JS, Springer JR, Jones DE, Hayes MJ, Shaffer AF, Jerome GM, Baratta MT, Zweifel B, Moore WM, Masferrer JL, et al. Discovery and SAR of PF-4693627, a potent, selective and orally bioavailable mPGES-1 inhibitor for the potential treatment of inflammation. Bioorganic & Medicinal Chemistry Letters. 23: 1114-9. PMID 23260349 DOI: 10.1016/J.Bmcl.2012.11.109  0.752
2013 Ordóñez P, Sharma K, Martin A, Reynolds W, Enriquez R, Malagón O, Jones D, Guzmán M, Compadre C. The Sesquiterpene Lactone Dehydroleucodine Shows Potent Anti-Leukemic Activity Planta Medica. 79. DOI: 10.1055/S-0033-1348566  0.694
2012 Gartia Y, Pulla S, Ramidi P, Farris CC, Nima Z, Jones DE, Biris AS, Ghosh A. A novel iron complex for cross-coupling reactions of multiple C-Cl bonds in polychlorinated solvents with grignard reagents Catalysis Letters. 142: 1397-1404. DOI: 10.1007/S10562-012-0913-2  0.756
2012 Gaffney JS, Marley NA, Jones DE. Fourier Transform Infrared (FTIR) Spectroscopy Characterization of Materials. 1-33. DOI: 10.1002/0471266965.Com107.Pub2  0.708
2011 Janetka JW, Agarwal M, Jones DE. Abstract LB-197: Hepatocyte Growth Factor Activator (HGFA) Inhibitors of c-MET/RON Kinase Signaling Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-197  0.741
2010 Jones DE, South MS. Synthesis of a versatile 2 (1H)-pyrazinone core for the preparation of Tissue Factor-Factor VIIa inhibitors Tetrahedron. 66: 2570-2581. DOI: 10.1016/J.Tet.2010.02.026  0.764
2010 Harmata M, Jones DE, Kahraman M, Sharma U, Barnes CL. ChemInform Abstract: Chiral Cations in 4 + 3 Cycloadditions. Cheminform. 30: no-no. DOI: 10.1002/chin.199923052  0.515
2010 ANGLE SR, BERNIER DS, CHANN K, JONES DE, KIM M, NEITZEL ML, WHITE SL. ChemInform Abstract: Stereoselective Synthesis of 2,3,4-Trisubstituted Tetrahydrofurans. Cheminform. 30: no-no. DOI: 10.1002/chin.199907124  0.777
2010 HARMATA M, KAHRAMAN M, JONES DE, PAVRI N, WEATHERWAX SE. ChemInform Abstract: The Reaction of N-Phenylsulfonimidoyl Chloride with Trimethylsilylethene. A New Route to 2-Alkenylanilines. Cheminform. 29: no-no. DOI: 10.1002/chin.199849105  0.517
2010 ANGLE SR, BERNIER DS, EL-SAID NA, JONES DE, SHAW SZ. ChemInform Abstract: Synthesis of Tetrahydrofurans from Protected β-Hydroxyaldehydes: Optimization of the Alcohol Protecting Group. Cheminform. 29: no-no. DOI: 10.1002/chin.199834135  0.775
2010 HARMATA M, JONES DE. ChemInform Abstract: Heteroatom-Stabilized Allylic Cations in ( 4 + 3) Cycloadditions. A Tandem Peterson Olefination/ (4 + 3) Cycloaddition Reaction. Cheminform. 28: no-no. DOI: 10.1002/chin.199736092  0.648
2010 HARMATA M, JONES DE. ChemInform Abstract: Vinyl Oxocarbenium Ions in Intermolecular (4 + 3) Cycloaddition Reactions. Cheminform. 28: no-no. DOI: 10.1002/chin.199728052  0.498
2010 HARMATA M, CARTER KW, JONES DE, KAHRAMAN M. ChemInform Abstract: The Metalation of Troeger′s Base. Cheminform. 27: no-no. DOI: 10.1002/chin.199648179  0.581
2010 HARMATA M, JONES DE. ChemInform Abstract: Intramolecular (4 + 3) Cycloadditions. Vinylthionium Ions from Allylic Alcohols. Cheminform. 27: no-no. DOI: 10.1002/chin.199622046  0.488
2010 HARMATA M, JONES DE. ChemInform Abstract: A General, Regioselective Approach to the Synthesis of ortho Allylanilines. Cheminform. 26: no-no. DOI: 10.1002/chin.199548098  0.531
2003 Parlow JJ, Case BL, Dice TA, Fenton RL, Hayes MJ, Jones DE, Neumann WL, Wood RS, Lachance RM, Girard TJ, Nicholson NS, Clare M, Stegeman RA, Stevens AM, Stallings WC, et al. Design, parallel synthesis, and crystal structures of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex. Journal of Medicinal Chemistry. 46: 4050-62. PMID 12954058 DOI: 10.1021/Jm030131L  0.759
2003 South MS, Case BL, Wood RS, Jones DE, Hayes MJ, Girard TJ, Lachance RM, Nicholson NS, Clare M, Stevens AM, Stegeman RA, Stallings WC, Kurumbail RG, Parlow JJ. Structure-based drug design of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex. Bioorganic & Medicinal Chemistry Letters. 13: 2319-25. PMID 12824026 DOI: 10.1016/S0960-894X(03)00410-4  0.757
1999 Harmata M, Jones DE, Kahraman M, Sharma U, Barnes CL. Chiral cations in 4+3 cycloadditions Tetrahedron Letters. 40: 1831-1834. DOI: 10.1016/S0040-4039(99)00080-5  0.724
1998 Angle SR, Bemier DS, Chann K, Jones DE, Kim M, Neitzel ML, White SL. Stereoselective synthesis of 2,3,4-trisubstituted tetrahydrofurans Tetrahedron Letters. 39: 8195-8198. DOI: 10.1016/S0040-4039(98)01873-5  0.715
1998 Angle SR, Bernier DS, El-Said NA, Jones DE, Shaw SZ. Synthesis of tetrahydrofurans from protected β-hydroxyaldehydes: Optimization of the alcohol protecting group Tetrahedron Letters. 39: 3919-3922. DOI: 10.1016/S0040-4039(98)00720-5  0.747
1998 Harmata M, Kahraman M, Jones DE, Pavri N, Weatherwax SE. The reaction of N-phenylsulfonimidoyl chloride with trimethylsilylethene. A new route to 2-alkenylanilines Tetrahedron. 54: 9995-10006. DOI: 10.1016/S0040-4020(98)00591-2  0.717
1997 Harmata M, Jones DE. Vinyl Oxocarbenium Ions in Intermolecular [4 + 3] Cycloaddition Reactions Journal of Organic Chemistry. 62: 1578-1579. DOI: 10.1021/Jo962374+  0.616
1997 Harmata M, Jones DE. Heteroatom-stabilized allylic cations in 4+3 cycloadditions. A tandem Peterson olefination/4+3 cycloaddition reaction Tetrahedron Letters. 38: 3861-3862. DOI: 10.1016/S0040-4039(97)00775-2  0.657
1996 Harmata M, Carter KW, Jones DE, Kahraman M. The metallation of Troeger's base Tetrahedron Letters. 37: 6267-6270. DOI: 10.1016/0040-4039(96)01392-5  0.773
1996 Harmata M, Jones DE. Intramolecular 4+3 cycloadditions. Vinylthionium ions from allylic alcohols Tetrahedron Letters. 37: 783-786. DOI: 10.1016/0040-4039(95)02391-7  0.654
1995 Harmata M, Gamlath CB, Barnes CL, Jones DE. Intramolecular [4 + 3] cycloadditions. Studies of relative asymmetric induction The Journal of Organic Chemistry. 60: 5077-5092. DOI: 10.1021/Jo00121A028  0.783
1995 Harmata M, Gamlath CB, Barnes CL, Jones DE. Intramolecular [4+3] Cycloadditions. Studies of Relative Asymmetric Induction The Journal of Organic Chemistry. 60: 5077-5092. DOI: 10.1021/jo00121a028  0.556
1995 Harmata M, Jones DE. A general, regioselective approach to the synthesis of ortho allylanilines Tetrahedron Letters. 36: 4769-4772. DOI: 10.1016/0040-4039(95)00929-7  0.663
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