Paul McCray, M.D. - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
cystic fibrosis, gene therapy

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Year Citation  Score
2019 Cooney AL, Thornell IM, Singh BK, Shah VS, Stoltz DA, McCray PB, Zabner J, Sinn PL. Novel AAV-mediated gene delivery system corrects CFTR function in pigs. American Journal of Respiratory Cell and Molecular Biology. PMID 31184507 DOI: 10.1165/rcmb.2019-0006OC  0.32
2018 Meyerholz DK, Stoltz DA, Gansemer ND, Ernst SE, Cook DP, Strub MD, LeClair EN, Barker CK, Adam RJ, Leidinger MR, Gibson-Corley KN, Karp PH, Welsh MJ, McCray PB. Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29467455 DOI: 10.1038/s41374-018-0026-7  0.32
2017 Li K, Wohlford-Lenane CL, Channappanavar R, Park JE, Earnest JT, Bair TB, Bates AM, Brogden KA, Flaherty HA, Gallagher T, Meyerholz DK, Perlman S, McCray PB. Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28348219 DOI: 10.1073/pnas.1619109114  0.32
2016 Cooney AL, Abou Alaiwa MH, Shah VS, Bouzek DC, Stroik MR, Powers LS, Gansemer ND, Meyerholz DK, Welsh MJ, Stoltz DA, Sinn PL, McCray PB. Lentiviral-mediated phenotypic correction of cystic fibrosis pigs. Jci Insight. 1. PMID 27656681 DOI: 10.1172/jci.insight.88730  0.32
2016 Bartlett JA, Ramachandran S, Wohlford-Lenane CL, Barker CK, Pezzulo AA, Zabner J, Welsh MJ, Meyerholz DK, Stoltz DA, McCray PB. Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus. American Journal of Respiratory and Critical Care Medicine. PMID 27027566 DOI: 10.1164/rccm.201510-2112OC  0.32
2016 Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB, Ostedgaard LS, Stoltz DA, et al. Airway acidification initiates host defense abnormalities in cystic fibrosis mice. Science (New York, N.Y.). 351: 503-7. PMID 26823428 DOI: 10.1126/science.aad5589  0.32
2015 Meyerholz DK, Lambertz AM, McCray PB. Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory Syndrome. The American Journal of Pathology. PMID 26597880 DOI: 10.1016/j.ajpath.2015.09.014  0.48
2015 Meyerholz DK, Lambertz AM, Reznikov LR, Ofori-Amanfo GK, Karp PH, McCray PB, Welsh MJ, Stoltz DA. Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans. Toxicologic Pathology. PMID 26511846 DOI: 10.1177/0192623315609691  0.32
2015 Li K, Wohlford-Lenane C, Perlman S, Zhao J, Jewell AK, Reznikov LR, Gibson-Corley KN, Meyerholz DK, McCray PB. Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4. The Journal of Infectious Diseases. PMID 26486634 DOI: 10.1093/infdis/jiv499  0.48
2015 Bartlett JA, Meyerholz DK, Wohlford-Lenane CL, Naumann PW, Salzman NH, McCray PB. Increased susceptibility to otitis media in a Splunc1-deficient mouse model. Disease Models & Mechanisms. 8: 501-8. PMID 25765466 DOI: 10.1242/dmm.019646  0.48
2015 Hiemstra PS, McCray PB, Bals R. The innate immune function of airway epithelial cells in inflammatory lung disease. The European Respiratory Journal. 45: 1150-62. PMID 25700381 DOI: 10.1183/09031936.00141514  0.48
2014 Krishnamurthy S, Behlke MA, Apicella MA, McCray PB, Davidson BL. Platelet Activating Factor Receptor Activation Improves siRNA Uptake and RNAi Responses in Well-differentiated Airway Epithelia. Molecular Therapy. Nucleic Acids. 3: e175. PMID 25025465 DOI: 10.1038/mtna.2014.26  0.48
2014 Weldon S, McNally P, McAuley DF, Oglesby IK, Wohlford-Lenane CL, Bartlett JA, Scott CJ, McElvaney NG, Greene CM, McCray PB, Taggart CC. miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production. American Journal of Respiratory and Critical Care Medicine. 190: 165-74. PMID 24940638 DOI: 10.1164/rccm.201311-1986OC  0.48
2014 Ramachandran S, Osterhaus SR, Karp PH, Welsh MJ, McCray PB. A genomic signature approach to rescue ΔF508-cystic fibrosis transmembrane conductance regulator biosynthesis and function. American Journal of Respiratory Cell and Molecular Biology. 51: 354-62. PMID 24669817 DOI: 10.1165/rcmb.2014-0007OC  0.48
2014 Zhao J, Li K, Wohlford-Lenane C, Agnihothram SS, Fett C, Zhao J, Gale MJ, Baric RS, Enjuanes L, Gallagher T, McCray PB, Perlman S. Rapid generation of a mouse model for Middle East respiratory syndrome. Proceedings of the National Academy of Sciences of the United States of America. 111: 4970-5. PMID 24599590 DOI: 10.1073/pnas.1323279111  0.48
2014 Berkebile AR, McCray PB. Effects of airway surface liquid pH on host defense in cystic fibrosis. The International Journal of Biochemistry & Cell Biology. 52: 124-9. PMID 24560894 DOI: 10.1016/j.biocel.2014.02.009  0.48
2014 Barlan A, Zhao J, Sarkar MK, Li K, McCray PB, Perlman S, Gallagher T. Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection. Journal of Virology. 88: 4953-61. PMID 24554656 DOI: 10.1128/JVI.00161-14  0.48
2014 Griffin MA, Restrepo MS, Abu-El-Haija M, Wallen T, Buchanan E, Rokhlina T, Chen YH, McCray PB, Davidson BL, Divekar A, Uc A. A novel gene delivery method transduces porcine pancreatic duct epithelial cells. Gene Therapy. 21: 123-30. PMID 24257348 DOI: 10.1038/gt.2013.62  0.48
2014 Guo JJ, Stoltz DA, Zhu V, Volk KA, Segar JL, McCray PB, Roghair RD. Genotype-specific alterations in vascular smooth muscle cell function in cystic fibrosis piglets. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. 13: 251-9. PMID 24183914 DOI: 10.1016/j.jcf.2013.10.009  0.48
2014 Fischer AJ, Singh SB, Adam RJ, Stoltz DA, Baranano CF, Kao S, Weinberger MM, McCray PB, Starner TD. Tracheomalacia is associated with lower FEV1 and Pseudomonas acquisition in children with CF. Pediatric Pulmonology. 49: 960-70. PMID 24166775 DOI: 10.1002/ppul.22922  0.48
2014 Derscheid RJ, van Geelen A, Berkebile AR, Gallup JM, Hostetter SJ, Banfi B, McCray PB, Ackermann MR. Increased concentration of iodide in airway secretions is associated with reduced respiratory syncytial virus disease severity. American Journal of Respiratory Cell and Molecular Biology. 50: 389-97. PMID 24053146 DOI: 10.1165/rcmb.2012-0529OC  0.48
2013 Perlman S, McCray PB. Person-to-person spread of the MERS coronavirus--an evolving picture. The New England Journal of Medicine. 369: 466-7. PMID 23902487 DOI: 10.1056/NEJMe1308724  0.48
2013 Li X, Burnight ER, Cooney AL, Malani N, Brady T, Sander JD, Staber J, Wheelan SJ, Joung JK, McCray PB, Bushman FD, Sinn PL, Craig NL. piggyBac transposase tools for genome engineering. Proceedings of the National Academy of Sciences of the United States of America. 110: E2279-87. PMID 23723351 DOI: 10.1073/pnas.1305987110  0.48
2013 Bartlett JA, Albertolle ME, Wohlford-Lenane C, Pezzulo AA, Zabner J, Niles RK, Fisher SJ, McCray PB, Williams KE. Protein composition of bronchoalveolar lavage fluid and airway surface liquid from newborn pigs. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L256-66. PMID 23709621 DOI: 10.1152/ajplung.00056.2013  0.48
2013 Stoltz DA, Rokhlina T, Ernst SE, Pezzulo AA, Ostedgaard LS, Karp PH, Samuel MS, Reznikov LR, Rector MV, Gansemer ND, Bouzek DC, Alaiwa MH, Hoegger MJ, Ludwig PS, Taft PJ, ... ... McCray PB, et al. Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs. The Journal of Clinical Investigation. 123: 2685-93. PMID 23676501 DOI: 10.1172/JCI68867  0.48
2013 Ramachandran S, Karp PH, Osterhaus SR, Jiang P, Wohlford-Lenane C, Lennox KA, Jacobi AM, Praekh K, Rose SD, Behlke MA, Xing Y, Welsh MJ, McCray PB. Post-transcriptional regulation of cystic fibrosis transmembrane conductance regulator expression and function by microRNAs. American Journal of Respiratory Cell and Molecular Biology. 49: 544-51. PMID 23646886 DOI: 10.1165/rcmb.2012-0430OC  0.48
2013 Ramachandran S, Krishnamurthy S, Jacobi AM, Wohlford-Lenane C, Behlke MA, Davidson BL, McCray PB. Efficient delivery of RNA interference oligonucleotides to polarized airway epithelia in vitro. American Journal of Physiology. Lung Cellular and Molecular Physiology. 305: L23-32. PMID 23624792 DOI: 10.1152/ajplung.00426.2012  0.48
2013 Liu Y, Bartlett JA, Di ME, Bomberger JM, Chan YR, Gakhar L, Mallampalli RK, McCray PB, Di YP. SPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infection. The American Journal of Pathology. 182: 1519-31. PMID 23499554 DOI: 10.1016/j.ajpath.2013.01.050  0.48
2013 Oakland M, Maury W, McCray PB, Sinn PL. Intrapulmonary Versus Nasal Transduction of Murine Airways With GP64-pseudotyped Viral Vectors. Molecular Therapy. Nucleic Acids. 2: e69. PMID 23360952 DOI: 10.1038/mtna.2012.60  0.48
2012 Burnight ER, Staber JM, Korsakov P, Li X, Brett BT, Scheetz TE, Craig NL, McCray PB. A Hyperactive Transposase Promotes Persistent Gene Transfer of a piggyBac DNA Transposon. Molecular Therapy. Nucleic Acids. 1: e50. PMID 23344650 DOI: 10.1038/mtna.2012.12  0.48
2012 Krishnamurthy S, Behlke MA, Ramachandran S, Salem AK, McCray PB, Davidson BL. Manipulation of Cell Physiology Enables Gene Silencing in Well-differentiated Airway Epithelia. Molecular Therapy. Nucleic Acids. 1: e41. PMID 23344182 DOI: 10.1038/mtna.2012.36  0.48
2012 Sinn PL, Cooney AL, Oakland M, Dylla DE, Wallen TJ, Pezzulo AA, Chang EH, McCray PB. Lentiviral vector gene transfer to porcine airways. Molecular Therapy. Nucleic Acids. 1: e56. PMID 23187455 DOI: 10.1038/mtna.2012.47  0.48
2012 Zhao J, Wohlford-Lenane C, Zhao J, Fleming E, Lane TE, McCray PB, Perlman S. Intranasal treatment with poly(I•C) protects aged mice from lethal respiratory virus infections. Journal of Virology. 86: 11416-24. PMID 22915814 DOI: 10.1128/JVI.01410-12  0.48
2012 Ramachandran S, Karp PH, Jiang P, Ostedgaard LS, Walz AE, Fisher JT, Keshavjee S, Lennox KA, Jacobi AM, Rose SD, Behlke MA, Welsh MJ, Xing Y, McCray PB. A microRNA network regulates expression and biosynthesis of wild-type and DeltaF508 mutant cystic fibrosis transmembrane conductance regulator. Proceedings of the National Academy of Sciences of the United States of America. 109: 13362-7. PMID 22853952 DOI: 10.1073/pnas.1210906109  0.48
2012 Pezzulo AA, Tang XX, Hoegger MJ, Alaiwa MH, Ramachandran S, Moninger TO, Karp PH, Wohlford-Lenane CL, Haagsman HP, van Eijk M, Bánfi B, Horswill AR, Stoltz DA, McCray PB, Welsh MJ, et al. Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung. Nature. 487: 109-13. PMID 22763554 DOI: 10.1038/nature11130  0.48
2012 Chang EH, Pezzulo AA, Meyerholz DK, Potash AE, Wallen TJ, Reznikov LR, Sieren JC, Karp PH, Ernst S, Moninger TO, Gansemer ND, McCray PB, Stoltz DA, Welsh MJ, Zabner J. Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis. The Laryngoscope. 122: 1898-905. PMID 22711071 DOI: 10.1002/lary.23392  0.48
2012 Abu-El-Haija M, Ramachandran S, Meyerholz DK, Abu-El-Haija M, Griffin M, Giriyappa RL, Stoltz DA, Welsh MJ, McCray PB, Uc A. Pancreatic damage in fetal and newborn cystic fibrosis pigs involves the activation of inflammatory and remodeling pathways. The American Journal of Pathology. 181: 499-507. PMID 22683312 DOI: 10.1016/j.ajpath.2012.04.024  0.48
2012 Li X, Comellas AP, Karp PH, Ernst SE, Moninger TO, Gansemer ND, Taft PJ, Pezzulo AA, Rector MV, Rossen N, Stoltz DA, McCray PB, Welsh MJ, Zabner J. CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 303: L152-60. PMID 22637155 DOI: 10.1152/ajplung.00116.2012  0.48
2012 Burnight ER, Wang G, McCray PB, Sinn PL. Transcriptional targeting in the airway using novel gene regulatory elements. American Journal of Respiratory Cell and Molecular Biology. 47: 227-33. PMID 22447971 DOI: 10.1165/rcmb.2011-0444OC  0.48
2012 Oakland M, Sinn PL, McCray PB. Advances in cell and gene-based therapies for cystic fibrosis lung disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1108-15. PMID 22371844 DOI: 10.1038/mt.2012.32  0.48
2012 Ramsey BW, Banks-Schlegel S, Accurso FJ, Boucher RC, Cutting GR, Engelhardt JF, Guggino WB, Karp CL, Knowles MR, Kolls JK, LiPuma JJ, Lynch S, McCray PB, Rubenstein RC, Singh PK, et al. Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report. American Journal of Respiratory and Critical Care Medicine. 185: 887-92. PMID 22312017 DOI: 10.1164/rccm.201111-2068WS  0.48
2012 Kohlgraf KG, Ackermann AR, Burnell KK, Srikantha RN, Joly SA, Bartlett JA, Gakhar L, Johnson GK, McCray PB, Guthmiller JM, Brogden KA. Quantitation of SPLUNC1 in saliva with an xMAP particle-based antibody capture and detection immunoassay. Archives of Oral Biology. 57: 197-204. PMID 21925642 DOI: 10.1016/j.archoralbio.2011.08.013  0.48
2011 Abu-El-Haija M, Sinkora M, Meyerholz DK, Welsh MJ, McCray PB, Butler J, Uc A. An activated immune and inflammatory response targets the pancreas of newborn pigs with cystic fibrosis. Pancreatology : Official Journal of the International Association of Pancreatology (Iap) ... [Et Al.]. 11: 506-15. PMID 22057257 DOI: 10.1159/000332582  0.48
2011 Mühlebach MD, Mateo M, Sinn PL, Prüfer S, Uhlig KM, Leonard VH, Navaratnarajah CK, Frenzke M, Wong XX, Sawatsky B, Ramachandran S, McCray PB, Cichutek K, von Messling V, Lopez M, et al. Adherens junction protein nectin-4 is the epithelial receptor for measles virus. Nature. 480: 530-3. PMID 22048310 DOI: 10.1038/nature10639  0.48
2011 Bartlett JA, Bartlett J, Gakhar L, Penterman J, Singh PK, Singh P, Mallampalli RK, Porter E, McCray PB. PLUNC: a multifunctional surfactant of the airways. Biochemical Society Transactions. 39: 1012-6. PMID 21787339 DOI: 10.1042/BST0391012  0.48
2011 Ramachandran S, Clarke LA, Scheetz TE, Amaral MD, McCray PB. Microarray mRNA expression profiling to study cystic fibrosis. Methods in Molecular Biology (Clifton, N.J.). 742: 193-212. PMID 21547734 DOI: 10.1007/978-1-61779-120-8_12  0.48
2011 Kondratowicz AS, Lennemann NJ, Sinn PL, Davey RA, Hunt CL, Moller-Tank S, Meyerholz DK, Rennert P, Mullins RF, Brindley M, Sandersfeld LM, Quinn K, Weller M, McCray PB, Chiorini J, et al. T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus. Proceedings of the National Academy of Sciences of the United States of America. 108: 8426-31. PMID 21536871 DOI: 10.1073/pnas.1019030108  0.48
2011 Brindley MA, Hunt CL, Kondratowicz AS, Bowman J, Sinn PL, McCray PB, Quinn K, Weller ML, Chiorini JA, Maury W. Tyrosine kinase receptor Axl enhances entry of Zaire ebolavirus without direct interactions with the viral glycoprotein. Virology. 415: 83-94. PMID 21529875 DOI: 10.1016/j.virol.2011.04.002  0.48
2011 Davidson BL, McCray PB. Current prospects for RNA interference-based therapies. Nature Reviews. Genetics. 12: 329-40. PMID 21499294 DOI: 10.1038/nrg2968  0.48
2011 Dylla DE, Xie L, Michele DE, Kunz S, McCray PB. Altering α-dystroglycan receptor affinity of LCMV pseudotyped lentivirus yields unique cell and tissue tropism. Genetic Vaccines and Therapy. 9: 8. PMID 21477292 DOI: 10.1186/1479-0556-9-8  0.48
2011 Schmidt NW, Mishra A, Lai GH, Davis M, Sanders LK, Tran D, Garcia A, Tai KP, McCray PB, Ouellette AJ, Selsted ME, Wong GC. Criterion for amino acid composition of defensins and antimicrobial peptides based on geometry of membrane destabilization. Journal of the American Chemical Society. 133: 6720-7. PMID 21473577 DOI: 10.1021/ja200079a  0.48
2011 Fischer AJ, Lennemann NJ, Krishnamurthy S, Pócza P, Durairaj L, Launspach JL, Rhein BA, Wohlford-Lenane C, Lorentzen D, Bánfi B, McCray PB. Enhancement of respiratory mucosal antiviral defenses by the oxidation of iodide. American Journal of Respiratory Cell and Molecular Biology. 45: 874-81. PMID 21441383 DOI: 10.1165/rcmb.2010-0329OC  0.48
2011 Sinn PL, Anthony RM, McCray PB. Genetic therapies for cystic fibrosis lung disease. Human Molecular Genetics. 20: R79-86. PMID 21422098 DOI: 10.1093/hmg/ddr104  0.48
2011 Ostedgaard LS, Meyerholz DK, Chen JH, Pezzulo AA, Karp PH, Rokhlina T, Ernst SE, Hanfland RA, Reznikov LR, Ludwig PS, Rogan MP, Davis GJ, Dohrn CL, Wohlford-Lenane C, Taft PJ, ... ... McCray PB, et al. The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs. Science Translational Medicine. 3: 74ra24. PMID 21411740 DOI: 10.1126/scitranslmed.3001868  0.48
2011 Lorentzen D, Durairaj L, Pezzulo AA, Nakano Y, Launspach J, Stoltz DA, Zamba G, McCray PB, Zabner J, Welsh MJ, Nauseef WM, Bánfi B. Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions. Free Radical Biology & Medicine. 50: 1144-50. PMID 21334431 DOI: 10.1016/j.freeradbiomed.2011.02.013  0.48
2011 Matsui H, Hegadorn C, Ozelo M, Burnett E, Tuttle A, Labelle A, McCray PB, Naldini L, Brown B, Hough C, Lillicrap D. A microRNA-regulated and GP64-pseudotyped lentiviral vector mediates stable expression of FVIII in a murine model of Hemophilia A. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 723-30. PMID 21285959 DOI: 10.1038/mt.2010.290  0.48
2011 Pezzulo AA, Starner TD, Scheetz TE, Traver GL, Tilley AE, Harvey BG, Crystal RG, McCray PB, Zabner J. The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 300: L25-31. PMID 20971803 DOI: 10.1152/ajplung.00256.2010  0.48
2011 Bartlett JA, Gakhar L, Penterman J, Singh PK, Mallampalli RK, Porter E, McCray PB. PLUNC: A multifunctional surfactant of the airways (Biochemical Society Transactions (2011) 39, PART 4 (1012-1016)) Biochemical Society Transactions. 39: 1549.  0.48
2010 Rogan MP, Reznikov LR, Pezzulo AA, Gansemer ND, Samuel M, Prather RS, Zabner J, Fredericks DC, McCray PB, Welsh MJ, Stoltz DA. Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth. Proceedings of the National Academy of Sciences of the United States of America. 107: 20571-5. PMID 21059918 DOI: 10.1073/pnas.1015281107  0.48
2010 Meyerholz DK, Stoltz DA, Namati E, Ramachandran S, Pezzulo AA, Smith AR, Rector MV, Suter MJ, Kao S, McLennan G, Tearney GJ, Zabner J, McCray PB, Welsh MJ. Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children. American Journal of Respiratory and Critical Care Medicine. 182: 1251-61. PMID 20622026 DOI: 10.1164/rccm.201004-0643OC  0.48
2010 Stoltz DA, Meyerholz DK, Pezzulo AA, Ramachandran S, Rogan MP, Davis GJ, Hanfland RA, Wohlford-Lenane C, Dohrn CL, Bartlett JA, Nelson GA, Chang EH, Taft PJ, Ludwig PS, Estin M, ... ... McCray PB, et al. Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth. Science Translational Medicine. 2: 29ra31. PMID 20427821 DOI: 10.1126/scitranslmed.3000928  0.48
2010 Gakhar L, Bartlett JA, Penterman J, Mizrachi D, Singh PK, Mallampalli RK, Ramaswamy S, McCray PB. PLUNC is a novel airway surfactant protein with anti-biofilm activity. Plos One. 5: e9098. PMID 20161732 DOI: 10.1371/journal.pone.0009098  0.48
2010 O'Keefe BR, Giomarelli B, Barnard DL, Shenoy SR, Chan PK, McMahon JB, Palmer KE, Barnett BW, Meyerholz DK, Wohlford-Lenane CL, McCray PB. Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae. Journal of Virology. 84: 2511-21. PMID 20032190 DOI: 10.1128/JVI.02322-09  0.48
2010 Griesenbach U, Meng C, Farley R, Wasowicz MY, Munkonge FM, Chan M, Stoneham C, Sumner-Jones SG, Pringle IA, Gill DR, Hyde SC, Stevenson B, Holder E, Ban H, Hasegawa M, ... ... McCray PB, et al. The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways. Biomaterials. 31: 2665-72. PMID 20022367 DOI: 10.1016/j.biomaterials.2009.12.005  0.48
2010 Banasik MB, McCray PB. Integrase-defective lentiviral vectors: progress and applications. Gene Therapy. 17: 150-7. PMID 19847206 DOI: 10.1038/gt.2009.135  0.48
2010 O'Keefe BR, Giomarelli B, Barnard DL, Shenoy SR, Chan PKS, McMahon JB, Palmer KE, Barnett BW, Meyerholz DK, Wohlford-Lenane CL, McCray PB. Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae (Journal of Virology (2010) 84, 5 (2511-2010)) Journal of Virology. 84: 5456. DOI: 10.1128/JVI.00537-10  0.48
2009 Winder AA, Wohlford-Lenane C, Scheetz TE, Nardy BN, Manzel LJ, Look DC, McCray PB. Differential effects of cytokines and corticosteroids on toll-like receptor 2 expression and activity in human airway epithelia. Respiratory Research. 10: 96. PMID 19835594 DOI: 10.1186/1465-9921-10-96  0.48
2009 Wohlford-Lenane CL, Meyerholz DK, Perlman S, Zhou H, Tran D, Selsted ME, McCray PB. Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease. Journal of Virology. 83: 11385-90. PMID 19710146 DOI: 10.1128/JVI.01363-09  0.48
2009 Sinn PL, Burnight ER, McCray PB. Progress and prospects: prospects of repeated pulmonary administration of viral vectors. Gene Therapy. 16: 1059-65. PMID 19641533 DOI: 10.1038/gt.2009.87  0.48
2009 Quinn K, Brindley MA, Weller ML, Kaludov N, Kondratowicz A, Hunt CL, Sinn PL, McCray PB, Stein CS, Davidson BL, Flick R, Mandell R, Staplin W, Maury W, Chiorini JA. Rho GTPases modulate entry of Ebola virus and vesicular stomatitis virus pseudotyped vectors. Journal of Virology. 83: 10176-86. PMID 19625394 DOI: 10.1128/JVI.00422-09  0.48
2009 Jia HP, Look DC, Tan P, Shi L, Hickey M, Gakhar L, Chappell MC, Wohlford-Lenane C, McCray PB. Ectodomain shedding of angiotensin converting enzyme 2 in human airway epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L84-96. PMID 19411314 DOI: 10.1152/ajplung.00071.2009  0.48
2009 Butler JE, Lager KM, Splichal I, Francis D, Kacskovics I, Sinkora M, Wertz N, Sun J, Zhao Y, Brown WR, DeWald R, Dierks S, Muyldermans S, Lunney JK, McCray PB, et al. The piglet as a model for B cell and immune system development. Veterinary Immunology and Immunopathology. 128: 147-70. PMID 19056129 DOI: 10.1016/j.vetimm.2008.10.321  0.48
2009 Fischer AJ, Goss KL, Scheetz TE, Wohlford-Lenane CL, Snyder JM, McCray PB. Differential gene expression in human conducting airway surface epithelia and submucosal glands. American Journal of Respiratory Cell and Molecular Biology. 40: 189-99. PMID 18703793 DOI: 10.1165/rcmb.2008-0240OC  0.48
2009 McCray PB, Ramachandran S, Fischer AJ, Bartlett JA, Meyerholz DK, Stoltz DA, Wohlford-Lenane CL, Starner TD, Taft PJ, Shilyansky J, Hanfland RA, Pezzulo A, Davis GJ, Rogan MP, Zabner J, et al. Pulmonary innate immunity and cystic fibrosis Pediatric Pulmonology. 44: 111-112.  0.48
2008 Kolls JK, McCray PB, Chan YR. Cytokine-mediated regulation of antimicrobial proteins. Nature Reviews. Immunology. 8: 829-35. PMID 18949018 DOI: 10.1038/nri2433  0.48
2008 Rogers CS, Stoltz DA, Meyerholz DK, Ostedgaard LS, Rokhlina T, Taft PJ, Rogan MP, Pezzulo AA, Karp PH, Itani OA, Kabel AC, Wohlford-Lenane CL, Davis GJ, Hanfland RA, Smith TL, ... ... McCray PB, et al. Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs. Science (New York, N.Y.). 321: 1837-41. PMID 18818360 DOI: 10.1126/science.1163600  0.48
2008 Sinn PL, Arias AC, Brogden KA, McCray PB. Lentivirus vector can be readministered to nasal epithelia without blocking immune responses. Journal of Virology. 82: 10684-92. PMID 18768988 DOI: 10.1128/JVI.00227-08  0.48
2008 Maeder ML, Thibodeau-Beganny S, Osiak A, Wright DA, Anthony RM, Eichtinger M, Jiang T, Foley JE, Winfrey RJ, Townsend JA, Unger-Wallace E, Sander JD, Müller-Lerch F, Fu F, Pearlberg J, ... ... McCray PB, et al. Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification. Molecular Cell. 31: 294-301. PMID 18657511 DOI: 10.1016/j.molcel.2008.06.016  0.48
2008 Leonard VH, Sinn PL, Hodge G, Miest T, Devaux P, Oezguen N, Braun W, McCray PB, McChesney MB, Cattaneo R. Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed. The Journal of Clinical Investigation. 118: 2448-58. PMID 18568079 DOI: 10.1172/JCI35454  0.48
2008 Bartlett JA, Fischer AJ, McCray PB. Innate immune functions of the airway epithelium. Contributions to Microbiology. 15: 147-63. PMID 18511860 DOI: 10.1159/000136349  0.48
2008 Rogers CS, Abraham WM, Brogden KA, Engelhardt JF, Fisher JT, McCray PB, McLennan G, Meyerholz DK, Namati E, Ostedgaard LS, Prather RS, Sabater JR, Stoltz DA, Zabner J, Welsh MJ. The porcine lung as a potential model for cystic fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 295: L240-63. PMID 18487356 DOI: 10.1152/ajplung.90203.2008  0.48
2008 Dylla DE, Michele DE, Campbell KP, McCray PB. Basolateral entry and release of New and Old World arenaviruses from human airway epithelia. Journal of Virology. 82: 6034-8. PMID 18417570 DOI: 10.1128/JVI.00100-08  0.48
2008 Bartlett JA, Hicks BJ, Schlomann JM, Ramachandran S, Nauseef WM, McCray PB. PLUNC is a secreted product of neutrophil granules. Journal of Leukocyte Biology. 83: 1201-6. PMID 18245229 DOI: 10.1189/jlb.0507302  0.48
2008 Hadina S, Weiss JP, McCray PB, Kulhankova K, Thorne PS. MD-2-dependent pulmonary immune responses to inhaled lipooligosaccharides: effect of acylation state. American Journal of Respiratory Cell and Molecular Biology. 38: 647-54. PMID 18203970 DOI: 10.1165/rcmb.2007-0418OC  0.48
2008 Marden JJ, Zhang Y, Oakley FD, Zhou W, Luo M, Jia HP, McCray PB, Yaniv M, Weitzman JB, Engelhardt JF. JunD protects the liver from ischemia/reperfusion injury by dampening AP-1 transcriptional activation. The Journal of Biological Chemistry. 283: 6687-95. PMID 18182393 DOI: 10.1074/jbc.M705606200  0.48
2008 Griesenbach U, Meng C, Farley R, Cheng SH, Scheule RK, Davies MH, Wolstenholme-Hogg PC, ten Hove W, van der Hoeven P, Sinn PL, McCray PB, Inoue M, Geddes DM, Hasegawa M, Frankel G, et al. In vivo imaging of gene transfer to the respiratory tract. Biomaterials. 29: 1533-40. PMID 18155138 DOI: 10.1016/j.biomaterials.2007.11.017  0.48
2008 Snively K, McCray P. Functional component testing for distributed simulations Simulation Interoperability Standards Organization - Simulation Interoperability Workshop Spring 2008, Workshop Papers. 415-420.  0.48
2007 Sinn PL, Goreham-Voss JD, Arias AC, Hickey MA, Maury W, Chikkanna-Gowda CP, McCray PB. Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector. Human Gene Therapy. 18: 1244-52. PMID 18052720 DOI: 10.1089/hum.2006.127  0.48
2007 Brindley MA, Hughes L, Ruiz A, McCray PB, Sanchez A, Sanders DA, Maury W. Ebola virus glycoprotein 1: identification of residues important for binding and postbinding events. Journal of Virology. 81: 7702-9. PMID 17475648 DOI: 10.1128/JVI.02433-06  0.48
2007 Flotte TR, Ng P, Dylla DE, McCray PB, Wang G, Kolls JK, Hu J. Viral vector-mediated and cell-based therapies for treatment of cystic fibrosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 229-41. PMID 17235299 DOI: 10.1038/sj.mt.6300002  0.48
2007 Moskwa P, Lorentzen D, Excoffon KJ, Zabner J, McCray PB, Nauseef WM, Dupuy C, Bánfi B. A novel host defense system of airways is defective in cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 175: 174-83. PMID 17082494 DOI: 10.1164/rccm.200607-1029OC  0.48
2007 McCray PB, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia HP, Halabi C, Sigmund CD, Meyerholz DK, Kirby P, Look DC, Perlman S. Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus. Journal of Virology. 81: 813-21. PMID 17079315 DOI: 10.1128/JVI.02012-06  0.48
2006 Viriyakosol S, McCray PB, Ashbaugh ME, Chu J, Jia HP, Weiss J, Kirkland TN. Characterization of monoclonal antibodies to human soluble MD-2 protein. Hybridoma (2005). 25: 349-57. PMID 17203997 DOI: 10.1089/hyb.2006.25.349  0.48
2006 Jia HP, Look DC, Hickey M, Shi L, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB. Infection of human airway epithelia by SARS coronavirus is associated with ACE2 expression and localization. Advances in Experimental Medicine and Biology. 581: 479-84. PMID 17037581 DOI: 10.1007/978-0-387-33012-9_85  0.48
2006 Meyerholz DK, Grubor B, Lazic T, Gallup JM, de Macedo MM, McCray PB, Ackermann MR. Monocytic/macrophagic pneumonitis after intrabronchial deposition of vascular endothelial growth factor in neonatal lambs. Veterinary Pathology. 43: 689-94. PMID 16966446 DOI: 10.1354/vp.43-5-689  0.48
2006 Kang Y, Moressi CJ, Scheetz TE, Xie L, Tran DT, Casavant TL, Ak P, Benham CJ, Davidson BL, McCray PB. Integration site choice of a feline immunodeficiency virus vector. Journal of Virology. 80: 8820-3. PMID 16912328 DOI: 10.1128/JVI.00719-06  0.48
2006 Starner TD, Zhang N, Kim G, Apicella MA, McCray PB. Haemophilus influenzae forms biofilms on airway epithelia: implications in cystic fibrosis. American Journal of Respiratory and Critical Care Medicine. 174: 213-20. PMID 16675778 DOI: 10.1164/rccm.200509-1459OC  0.48
2005 Cong W, Wang G, Kumar D, Liu Y, Jiang M, Wang L, Hoffman E, McLennan G, McCray P, Zabner J, Cong A. Practical reconstruction method for bioluminescence tomography. Optics Express. 13: 6756-71. PMID 19498692 DOI: 10.1364/OPEX.13.006756  0.48
2005 Starner TD, McCray PB. Pathogenesis of early lung disease in cystic fibrosis: a window of opportunity to eradicate bacteria. Annals of Internal Medicine. 143: 816-22. PMID 16330793  0.48
2005 Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. Journal of Virology. 79: 14614-21. PMID 16282461 DOI: 10.1128/JVI.79.23.14614-14621.2005  0.48
2005 Sinn PL, Burnight ER, Hickey MA, Blissard GW, McCray PB. Persistent gene expression in mouse nasal epithelia following feline immunodeficiency virus-based vector gene transfer. Journal of Virology. 79: 12818-27. PMID 16188984 DOI: 10.1128/JVI.79.20.12818-12827.2005  0.48
2005 Sinn PL, Sauter SL, McCray PB. Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production. Gene Therapy. 12: 1089-98. PMID 16003340 DOI: 10.1038/sj.gt.3302570  0.48
2005 Zabner J, Scheetz TE, Almabrazi HG, Casavant TL, Huang J, Keshavjee S, McCray PB. CFTR DeltaF508 mutation has minimal effect on the gene expression profile of differentiated human airway epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L545-53. PMID 15937068 DOI: 10.1152/ajplung.00065.2005  0.48
2005 Kang Y, Xie L, Tran DT, Stein CS, Hickey M, Davidson BL, McCray PB. Persistent expression of factor VIII in vivo following nonprimate lentiviral gene transfer. Blood. 106: 1552-8. PMID 15886327 DOI: 10.1182/blood-2004-11-4358  0.48
2005 Sinn PL, Penisten AK, Burnight ER, Hickey MA, Williams G, McCoy DM, Mallampalli RK, McCray PB. Gene transfer to respiratory epithelia with lentivirus pseudotyped with Jaagsiekte sheep retrovirus envelope glycoprotein. Human Gene Therapy. 16: 479-88. PMID 15871679 DOI: 10.1089/hum.2005.16.479  0.48
2005 Joly S, Organ CC, Johnson GK, McCray PB, Guthmiller JM. Correlation between beta-defensin expression and induction profiles in gingival keratinocytes. Molecular Immunology. 42: 1073-84. PMID 15829297 DOI: 10.1016/j.molimm.2004.11.001  0.48
2005 Sinn PL, Burnight ER, Shen H, Fan H, McCray PB. Inclusion of Jaagsiekte sheep retrovirus proviral elements markedly increases lentivirus vector pseudotyping efficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 460-9. PMID 15727943 DOI: 10.1016/j.ymthe.2004.10.022  0.48
2005 Sinn PL, Shah AJ, Donovan MD, McCray PB. Viscoelastic gel formulations enhance airway epithelial gene transfer with viral vectors. American Journal of Respiratory Cell and Molecular Biology. 32: 404-10. PMID 15695737 DOI: 10.1165/rcmb.2004-0410OC  0.48
2005 Starner TD, Agerberth B, Gudmundsson GH, McCray PB. Expression and activity of beta-defensins and LL-37 in the developing human lung. Journal of Immunology (Baltimore, Md. : 1950). 174: 1608-15. PMID 15661923  0.48
2004 Bartlett KH, McCray PB, Thorne PS. Reduction in the bactericidal activity of selected cathelicidin peptides by bovine calf serum or exogenous endotoxin. International Journal of Antimicrobial Agents. 23: 606-12. PMID 15194132 DOI: 10.1016/j.ijantimicag.2004.02.018  0.48
2004 Jia HP, Kline JN, Penisten A, Apicella MA, Gioannini TL, Weiss J, McCray PB. Endotoxin responsiveness of human airway epithelia is limited by low expression of MD-2. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L428-37. PMID 15121639 DOI: 10.1152/ajplung.00377.2003  0.48
2004 Bissell J, Joly S, Johnson GK, Organ CC, Dawson D, McCray PB, Guthmiller JM. Expression of beta-defensins in gingival health and in periodontal disease. Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 33: 278-85. PMID 15078488 DOI: 10.1111/j.0904-2512.2004.00143.x  0.48
2004 Joly S, Maze C, McCray PB, Guthmiller JM. Human beta-defensins 2 and 3 demonstrate strain-selective activity against oral microorganisms. Journal of Clinical Microbiology. 42: 1024-9. PMID 15004048 DOI: 10.1128/JCM.42.3.1024-1029.2004  0.48
2004 Premratanachai P, Joly S, Johnson GK, McCray PB, Jia HP, Guthmiller JM. Expression and regulation of novel human beta-defensins in gingival keratinocytes. Oral Microbiology and Immunology. 19: 111-7. PMID 14871351 DOI: 10.1111/j.0902-0055.2002.00127.x  0.48
2004 Shasby DM, McCray P. Sepsis and innate immunity. American Journal of Respiratory and Critical Care Medicine. 169: 144-5. PMID 14718231 DOI: 10.1164/rccm.2311003  0.48
2004 Scheetz TE, Zabner J, Welsh MJ, Coco J, Eyestone Mde F, Bonaldo M, Kucaba T, Casavant TL, Soares MB, McCray PB. Large-scale gene discovery in human airway epithelia reveals novel transcripts. Physiological Genomics. 17: 69-77. PMID 14701920 DOI: 10.1152/physiolgenomics.00188.2003  0.48
2004 Meyerholz DK, Gallup JM, Grubor BM, Evans RB, Tack BF, McCray PB, Ackermann MR. Developmental expression and distribution of sheep beta-defensin-2. Developmental and Comparative Immunology. 28: 171-8. PMID 12969802 DOI: 10.1016/S0145-305X(03)00105-8  0.48
2003 Bartlett KH, McCray PB, Thorne PS. Novispirin G10-induced lung toxicity in a Klebsiella pneumoniae infection model. Antimicrobial Agents and Chemotherapy. 47: 3901-6. PMID 14638500 DOI: 10.1128/AAC.47.12.3901-3906.2003  0.48
2003 Brogden KA, Ackermann M, McCray PB, Tack BF. Antimicrobial peptides in animals and their role in host defences. International Journal of Antimicrobial Agents. 22: 465-78. PMID 14602364 DOI: 10.1016/S0924-8579(03)00180-8  0.48
2003 Taggart CC, Greene CM, Smith SG, Levine RL, McCray PB, O'Neill S, McElvaney NG. Inactivation of human beta-defensins 2 and 3 by elastolytic cathepsins. Journal of Immunology (Baltimore, Md. : 1950). 171: 931-7. PMID 12847264  0.48
2003 Sinn PL, McCray PB. Cells of respiratory epithelium. Methods in Molecular Biology (Clifton, N.J.). 229: 287-98. PMID 12824638  0.48
2003 Starner TD, Barker CK, Jia HP, Kang Y, McCray PB. CCL20 is an inducible product of human airway epithelia with innate immune properties. American Journal of Respiratory Cell and Molecular Biology. 29: 627-33. PMID 12748059 DOI: 10.1165/rcmb.2002-0272OC  0.48
2003 Sinn PL, Hickey MA, Staber PD, Dylla DE, Jeffers SA, Davidson BL, Sanders DA, McCray PB. Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha. Journal of Virology. 77: 5902-10. PMID 12719583 DOI: 10.1128/JVI.77.10.5902-5910.2003  0.48
2003 Brogden KA, Heidari M, Sacco RE, Palmquist D, Guthmiller JM, Johnson GK, Jia HP, Tack BF, McCray PB. Defensin-induced adaptive immunity in mice and its potential in preventing periodontal disease. Oral Microbiology and Immunology. 18: 95-9. PMID 12654098 DOI: 10.1034/j.1399-302X.2003.00047.x  0.48
2002 Scheetz T, Bartlett JA, Walters JD, Schutte BC, Casavant TL, McCray PB. Genomics-based approaches to gene discovery in innate immunity. Immunological Reviews. 190: 137-45. PMID 12493011 DOI: 10.1034/j.1600-065X.2002.19010.x  0.48
2002 Kang Y, Stein CS, Heth JA, Sinn PL, Penisten AK, Staber PD, Ratliff KL, Shen H, Barker CK, Martins I, Sharkey CM, Sanders DA, McCray PB, Davidson BL. In vivo gene transfer using a nonprimate lentiviral vector pseudotyped with Ross River Virus glycoproteins. Journal of Virology. 76: 9378-88. PMID 12186920 DOI: 10.1128/JVI.76.18.9378-9388.2002  0.48
2002 Starner TD, Swords WE, Apicella MA, McCray PB. Susceptibility of nontypeable Haemophilus influenzae to human beta-defensins is influenced by lipooligosaccharide acylation. Infection and Immunity. 70: 5287-9. PMID 12183584 DOI: 10.1128/IAI.70.9.5287-5289.2002  0.48
2002 Nakamura K, Stokes JB, McCray PB. Endogenous and exogenous glucocorticoid regulation of ENaC mRNA expression in developing kidney and lung. American Journal of Physiology. Cell Physiology. 283: C762-72. PMID 12176733 DOI: 10.1152/ajpcell.00029.2002  0.48
2002 Wang G, Williams G, Xia H, Hickey M, Shao J, Davidson BL, McCray PB. Apical barriers to airway epithelial cell gene transfer with amphotropic retroviral vectors. Gene Therapy. 9: 922-31. PMID 12085240 DOI: 10.1038/sj.gt.3301714  0.48
2002 Sawai MV, Waring AJ, Kearney WR, McCray PB, Forsyth WR, Lehrer RI, Tack BF. Impact of single-residue mutations on the structure and function of ovispirin/novispirin antimicrobial peptides. Protein Engineering. 15: 225-32. PMID 11932493  0.48
2002 Wang G, Sinn PL, Zabner J, McCray PB. Gene transfer to airway epithelia using feline immunodeficiency virus-based lentivirus vectors. Methods in Enzymology. 346: 500-14. PMID 11883087 DOI: 10.1016/S0076-6879(02)46073-9  0.48
2002 Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, McCray PB. Discovery of five conserved beta -defensin gene clusters using a computational search strategy. Proceedings of the National Academy of Sciences of the United States of America. 99: 2129-33. PMID 11854508 DOI: 10.1073/pnas.042692699  0.48
2002 Sinn PL, Williams G, Vongpunsawad S, Cattaneo R, McCray PB. Measles virus preferentially transduces the basolateral surface of well-differentiated human airway epithelia. Journal of Virology. 76: 2403-9. PMID 11836418 DOI: 10.1128/jvi.76.5.2403-2409.2002  0.48
2002 Schutte BC, McCray PB. [beta]-defensins in lung host defense. Annual Review of Physiology. 64: 709-48. PMID 11826286 DOI: 10.1146/annurev.physiol.64.081501.134340  0.48
2002 Schibli DJ, Hunter HN, Aseyev V, Starner TD, Wiencek JM, McCray PB, Tack BF, Vogel HJ. The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus. The Journal of Biological Chemistry. 277: 8279-89. PMID 11741980 DOI: 10.1074/jbc.M108830200  0.48
2001 McCray PB. Cystic fibrosis. Difficulties of gene therapy Lancet. 358: S19. PMID 11784568  0.48
2001 Carothers DG, Graham SM, Jia HP, Ackermann MR, Tack BF, McCray PB. Production of β-defensin antimicrobial peptides by maxillary sinus mucosa American Journal of Rhinology. 15: 175-179. PMID 11453504  0.48
2001 Stein CS, Kang Y, Sauter SL, Townsend K, Staber P, Derksen TA, Martins I, Qian J, Davidson BL, McCray PB. In vivo treatment of hemophilia A and mucopolysaccharidosis type VII using nonprimate lentiviral vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 850-6. PMID 11407898 DOI: 10.1006/mthe.2001.0325  0.48
2001 Sanlioglu S, Williams CM, Samavati L, Butler NS, Wang G, McCray PB, Ritchie TC, Hunninghake GW, Zandi E, Engelhardt JF. Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B. The Journal of Biological Chemistry. 276: 30188-98. PMID 11402028 DOI: 10.1074/jbc.M102061200  0.48
2001 Sawai MV, Jia HP, Liu L, Aseyev V, Wiencek JM, McCray PB, Ganz T, Kearney WR, Tack BF. The NMR structure of human β-defensin-2 reveals a novel α-helical segment Biochemistry. 40: 3810-3816. PMID 11300761 DOI: 10.1021/bi002519d  0.48
2001 Slepushkin VA, Staber PD, Wang G, McCray PB, Davidson BL. Infection of human airway epithelia with H1N1, H2N2, and H3N2 influenza A virus strains. Molecular Therapy : the Journal of the American Society of Gene Therapy. 3: 395-402. PMID 11273782 DOI: 10.1006/mthe.2001.0277  0.48
2001 Peng Jia H, Schutte BC, Schudy A, Linzmeier R, Guthmiller JM, Johnson GK, Tack BF, Mitros JP, Rosenthal A, Ganz T, McCray PB. Discovery of new human β-defensins using a genomics-based approach Gene. 263: 211-218. PMID 11223260 DOI: 10.1016/S0378-1119(00)00569-2  0.48
2001 Jia HP, Starner T, Ackermann M, Kirby P, Tack BF, McCray PB. Abundant human beta-defensin-1 expression in milk and mammary gland epithelium. The Journal of Pediatrics. 138: 109-12. PMID 11148522 DOI: 10.1067/mpd.2001.109375  0.48
2000 Singh PK, Tack BF, McCray PB, Welsh MJ. Synergistic and additive killing by antimicrobial factors found in human airway surface liquid. American Journal of Physiology. Lung Cellular and Molecular Physiology. 279: L799-805. PMID 11053013  0.48
2000 Jia HP, Wowk SA, Schutte BC, Lee SK, Vivado A, Tack BF, Bevins CL, McCray PB. A novel murine β-defensin expressed in tongue, esophagus, and trachea* Journal of Biological Chemistry. 275: 33314-33320. PMID 10922379 DOI: 10.1074/jbc.M006603200  0.48
2000 Nakamura KT, McCray PB. Fetal airway smooth-muscle contractility and lung development: A player in the band or just someone in the audience? American Journal of Respiratory Cell and Molecular Biology. 23: 3-6. PMID 10873146  0.48
2000 Travis SM, Anderson NN, Forsyth WR, Espiritu C, Conway BD, Greenberg EP, McCray PB, Lehrer RI, Welsh MJ, Tack BF. Bactericidal activity of mammalian cathelicidin-derived peptides. Infection and Immunity. 68: 2748-55. PMID 10768969 DOI: 10.1128/IAI.68.5.2748-2755.2000  0.48
2000 Wang G, Zabner J, Deering C, Launspach J, Shao J, Bodner M, Jolly DJ, Davidson BL, McCray PB. Increasing epithelial junction permeability enhances gene transfer to airway epithelia In vivo. American Journal of Respiratory Cell and Molecular Biology. 22: 129-38. PMID 10657931 DOI: 10.1165/ajrcmb.22.2.3938  0.48
2000 McCray PB, Wang G, Scott J, Davidson BL. Modulation of epithelial junction permeability to enhance gene transfer Pediatric Pulmonology. 30: 153-155.  0.48
1999 Wang G, Slepushkin VA, Bodner M, Zabner J, van Es HH, Thomas P, Jolly DJ, Davidson BL, McCray PB. Keratinocyte growth factor induced epithelial proliferation facilitates retroviral-mediated gene transfer to distal lung epithelia in vivo. The Journal of Gene Medicine. 1: 22-30. PMID 10738582 DOI: 10.1002/(SICI)1521-2254(199901/02)1:1<22::AID-JGM1>3.0.CO;2-X  0.48
1999 Wang G, Slepushkin V, Zabner J, Keshavjee S, Johnston JC, Sauter SL, Jolly DJ, Dubensky TW, Davidson BL, McCray PB. Feline immunodeficiency virus vectors persistently transduce nondividing airway epithelia and correct the cystic fibrosis defect. The Journal of Clinical Investigation. 104: R55-62. PMID 10587528 DOI: 10.1172/JCI8390  0.48
1999 Graeff RW, Wang G, McCray PB. KGF and FGF-10 stimulate liquid secretion in human fetal lung. Pediatric Research. 46: 523-9. PMID 10541313 DOI: 10.1203/00006450-199911000-00006  0.48
1999 Bøe R, Silvola J, Yang J, Moens U, Mccray PB, Stenfors LE, Seljfelid R. Human β-defensin-1 mRNA is transcribed in tympanic membrane and adjacent auditory canal epithelium Infection and Immunity. 67: 4843-4846. PMID 10456939  0.48
1999 Jia HP, Mills JN, Barahmand-Pour F, Nishimura D, Mallampali RK, Wang G, Wiles K, Tack BF, Bevins CL, Mccray PB. Molecular cloning and characterization of rat genes encoding homologues of human β-defensins Infection and Immunity. 67: 4827-4833. PMID 10456937  0.48
1999 Brogden KA, Ackermann MR, McCray PB, Huttner KM. Differences in the concentrations of small, anionic, antimicrobial peptides in bronchoalveolar lavage fluid and in respiratory epithelia of patients with and without cystic fibrosis Infection and Immunity. 67: 4256-4259. PMID 10417200  0.48
1999 McCray PB, Zabner J, Jia HP, Welsh MJ, Thorne PS. Efficient killing of inhaled bacteria in DeltaF508 mice: role of airway surface liquid composition. The American Journal of Physiology. 277: L183-90. PMID 10409246  0.48
1999 Thorne PS, McCray PB, Howe TS, O'Neill MA. Early-onset inflammatory responses in vivo to adenoviral vectors in the presence or absence of lipopolysaccharide-induced inflammation. American Journal of Respiratory Cell and Molecular Biology. 20: 1155-64. PMID 10340934 DOI: 10.1165/ajrcmb.20.6.3632  0.48
1999 Mathews M, Jia HP, Guthmiller JM, Losh G, Graham S, Johnson GK, Tack BF, McCray PB. Production of β-defensin antimicrobial peptides by the oral mucosa and salivary glands Infection and Immunity. 67: 2740-2745. PMID 10338476  0.48
1999 Sparrow MP, Weichselbaum M, McCray PB. Development of the innervation and airway smooth muscle in human fetal lung American Journal of Respiratory Cell and Molecular Biology. 20: 550-560. PMID 10100986  0.48
1999 McDonald FJ, Yang B, Hrstka RF, Drummond HA, Tarr DE, McCray PB, Stokes JB, Welsh MJ, Williamson RA. Disruption of the beta subunit of the epithelial Na+ channel in mice: hyperkalemia and neonatal death associated with a pseudohypoaldosteronism phenotype. Proceedings of the National Academy of Sciences of the United States of America. 96: 1727-31. PMID 9990092 DOI: 10.1073/pnas.96.4.1727  0.48
1999 Watanabe S, Matsushita K, McCray PB, Stokes JB. Developmental expression of the epithelial Na+ channel in kidney and uroepithelia American Journal of Physiology - Renal Physiology. 276: F304-F314. PMID 9950962  0.48
1998 Duan D, Yue Y, Yan Z, Mccray PB, Engelhardt JF. Polarity influences the efficiency of recombinant adenoassociated virus infection in differentiated airway epithelia Human Gene Therapy. 9: 2761-2776. PMID 9874274  0.48
1998 Singh PK, Jia HP, Wiles K, Hesselberth J, Liu L, Conway BA, Greenberg EP, Valore EV, Welsh MJ, Ganz T, Tack BF, McCray PB. Production of beta-defensins by human airway epithelia. Proceedings of the National Academy of Sciences of the United States of America. 95: 14961-6. PMID 9843998 DOI: 10.1073/pnas.95.25.14961  0.48
1998 Watanabe S, Matsushita K, Stokes JB, McCray PB. Developmental regulation of epithelial sodium channel subunit mRNA expression in rat colon and lung American Journal of Physiology - Gastrointestinal and Liver Physiology. 275: G1227-G1235. PMID 9843757  0.48
1998 Liu L, Wang L, Jia HP, Zhao C, Heng HHQ, Schutte BC, McCray PB, Ganz T. Structure and mapping of the human β-defensin HBD-2 gene and its expression at sites of inflammation Gene. 222: 237-244. PMID 9831658 DOI: 10.1016/S0378-1119(98)00480-6  0.48
1998 Wang G, Davidson BL, Melchert P, Slepushkin VA, van Es HH, Bodner M, Jolly DJ, McCray PB. Influence of cell polarity on retrovirus-mediated gene transfer to differentiated human airway epithelia. Journal of Virology. 72: 9818-26. PMID 9811717  0.48
1998 Wang G, Williamson R, Mueller G, Thomas P, Davidson BL, McCray PB. Ultrasound-guided gene transfer to hepatocytes in utero. Fetal Diagnosis and Therapy. 13: 197-205. PMID 9784638 DOI: 10.1159/000020838  0.48
1998 Bosch A, McCray PB, Walters KS, Bodner M, Jolly DJ, van Es HH, Nakamura T, Matsumoto K, Davidson BL. Effects of keratinocyte and hepatocyte growth factor in vivo: implications for retrovirus-mediated gene transfer to liver. Human Gene Therapy. 9: 1747-54. PMID 9721085 DOI: 10.1089/hum.1998.9.12-1747  0.48
1998 Valore EV, Park CH, Quayle AJ, Wiles KR, McCray PB, Ganz T. Human β-defensin-1: An antimicrobial peptide of urogenital tissues Journal of Clinical Investigation. 101: 1633-1642. PMID 9541493  0.48
1998 Watanabe S, Matsushita K, McCray PB, Stokes JB. Developmental expression of the Epithelial Na Channel (ENaC) in rat kidney and uroepithelium Faseb Journal. 12: A983.  0.48
1997 Maschka DA, Bauman NM, McCray PB, Hoffman HT, Karnell MP, Smith RJH. A classification scheme for paradoxical vocal cord motion Laryngoscope. 107: 1429-1435. PMID 9369385 DOI: 10.1097/00005537-199711000-00002  0.48
1997 Scher H, Bishop WP, McCray PB. Ursodeoxycholic acid improves cholestasis in infants with cystic fibrosis Annals of Pharmacotherapy. 31: 1003-1005. PMID 9296240  0.48
1997 McCray PB, Wang G, Kline JN, Zabner J, Chada S, Jolly DJ, Chang SM, Davidson BL. Alveolar macrophages inhibit retrovirus-mediated gene transfer to airway epithelia. Human Gene Therapy. 8: 1087-93. PMID 9189766 DOI: 10.1089/hum.1997.8.9-1087  0.48
1997 McCray PB, Bentley L. Human Airway Epithelia Express a β-defensin American Journal of Respiratory Cell and Molecular Biology. 16: 343-349. PMID 9070620  0.48
Low-probability matches
2019 Berkebile AR, Bartlett JA, Abou Alaiwa M, Varga SM, Power UF, McCray PB. Airway surface liquid has innate antiviral activity that is reduced in cystic fibrosis. American Journal of Respiratory Cell and Molecular Biology. PMID 31242392 DOI: 10.1165/rcmb.2018-0304OC  0.28
2019 Krishnamurthy S, Wohlford-Lenane C, Kandimalla S, Sartre G, Meyerholz DK, Théberge V, Hallée S, Duperré AM, Del'Guidice T, Lepetit-Stoffaes JP, Barbeau X, Guay D, McCray PB. Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia. Nature Communications. 10: 4906. PMID 31659165 DOI: 10.1038/s41467-019-12922-y  0.24
2019 Channappanavar R, Fehr AR, Zheng J, Wohlford-Lenane C, Abrahante JE, Mack M, Sompallae R, McCray PB, Meyerholz DK, Perlman S. IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. The Journal of Clinical Investigation. 130. PMID 31355779 DOI: 10.1172/JCI126363  0.24
2017 Gray RD, Hardisty G, Regan KH, Smith M, Robb CT, Duffin R, Mackellar A, Felton JM, Paemka L, McCullagh BN, Lucas CD, Dorward DA, McKone EF, Cooke G, Donnelly SC, ... ... McCray PB, et al. Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis. Thorax. PMID 28916704 DOI: 10.1136/thoraxjnl-2017-210134  0.24
2017 Paemka L, McCullagh BN, Abou Alaiwa MH, Stoltz DA, Dong Q, Randak CO, Gray RD, McCray PB. Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 28377087 DOI: 10.1016/j.jcf.2017.03.007  0.24
2016 Ramachandran S, Osterhaus SR, Parekh KR, Jacobi AM, Behlke MA, McCray PB. SYVN1, NEDD8, and FBXO2 Regulate ΔF508-CFTR Ubiquitin-Mediated Proteasomal Degradation. The Journal of Biological Chemistry. PMID 27756846 DOI: 10.1074/jbc.M116.754283  0.24
2016 Alper S, Warg LA, De Arras L, Flatley BR, Davidson EJ, Adams J, Smith K, Wohlford-Lenane CL, McCray PB, Pedersen BS, Schwartz DA, Yang IV. Novel Innate Immune Genes Regulating the Macrophage Response to Gram Positive Bacteria. Genetics. PMID 27356610 DOI: 10.1534/genetics.115.185314  0.24
2018 Cooney AL, McCray PB, Sinn PL. Cystic Fibrosis Gene Therapy: Looking Back, Looking Forward. Genes. 9. PMID 30405068 DOI: 10.3390/genes9110538  0.2
2015 Yan Z, Stewart ZA, Sinn PL, Olsen JC, Hu J, McCray PB, Engelhardt JF. Ferret and pig models of cystic fibrosis: prospects and promise for gene therapy. Human Gene Therapy. Clinical Development. 26: 38-49. PMID 25675143 DOI: 10.1089/humc.2014.154  0.16
2014 Staber JM, Pollpeter MJ, Arensdorf A, Sinn PL, Rutkowski DT, McCray PB. piggyBac-mediated phenotypic correction of factor VIII deficiency. Molecular Therapy. Methods & Clinical Development. 1: 14042. PMID 26015980 DOI: 10.1038/mtm.2014.42  0.16
2016 Park JE, Li K, Barlan A, Fehr AR, Perlman S, McCray PB, Gallagher T. Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism. Proceedings of the National Academy of Sciences of the United States of America. 113: 12262-12267. PMID 27791014 DOI: 10.1073/pnas.1608147113  0.08
2017 Sodhi CP, Wohlford-Lenane C, Yamaguchi Y, Prindle T, Fulton WB, Wang S, McCray PB, Chappell MC, Hackam DJ, Jia H. Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg9 bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00498.2016. PMID 28935640 DOI: 10.1152/ajplung.00498.2016  0.04
2015 Guevara C, Zhang C, Gaddy JA, Iqbal J, Guerra J, Greenberg DP, Decker MD, Carbonetti N, Starner TD, McCray PB, Mooi FR, Gómez-Duarte OG. Highly differentiated human airway epithelial cells: a model to study host cell-parasite interactions in pertussis. Infectious Diseases (London, England). 1-12. PMID 26492208 DOI: 10.3109/23744235.2015.1100323  0.04
2002 Brooks AI, Stein CS, Hughes SM, Heth J, McCray PM, Sauter SL, Johnston JC, Cory-Slechta DA, Federoff HJ, Davidson BL. Functional correction of established central nervous system deficits in an animal model of lysosomal storage disease with feline immunodeficiency virus-based vectors. Proceedings of the National Academy of Sciences of the United States of America. 99: 6216-21. PMID 11959904 DOI: 10.1073/pnas.082011999  0.04
2019 Yan Z, McCray PB, Engelhardt JF. Advances In Gene Therapy For Cystic Fibrosis Lung Disease. Human Molecular Genetics. PMID 31332440 DOI: 10.1093/hmg/ddz139  0.01
2019 Marquez Loza LI, Yuen EC, McCray PB. Lentiviral Vectors for the Treatment and Prevention of Cystic Fibrosis Lung Disease. Genes. 10. PMID 30875857 DOI: 10.3390/genes10030218  0.01
2019 Lueck JD, Yoon JS, Perales-Puchalt A, Mackey AL, Infield DT, Behlke MA, Pope MR, Weiner DB, Skach WR, McCray PB, Ahern CA. Engineered transfer RNAs for suppression of premature termination codons. Nature Communications. 10: 822. PMID 30778053 DOI: 10.1038/s41467-019-08329-4  0.01
2017 Wei H, Chen Z, Elson A, Li Z, Abraham M, Phan S, Kristhnamurthy S, McCray PB, Andrews S, Stice S, Sakamoto K, Jones C, Tompkins SM, He B. Developing a platform system for gene delivery: amplifying virus-like particles (AVLP) as an influenza vaccine. Npj Vaccines. 2: 32. PMID 29263887 DOI: 10.1038/s41541-017-0031-7  0.01
2017 Earnest JT, Hantak MP, Li K, McCray PB, Perlman S, Gallagher T. The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases. Plos Pathogens. 13: e1006546. PMID 28759649 DOI: 10.1371/journal.ppat.1006546  0.01
2015 Gray RD, McCullagh BN, McCray PB. NETs and CF Lung Disease: Current Status and Future Prospects. Antibiotics (Basel, Switzerland). 4: 62-75. PMID 27025615 DOI: 10.3390/antibiotics4010062  0.01
2014 Gurman TA, Trappler RM, Acosta A, McCray PA, Cooper CM, Goodsmith L. 'By seeing with our own eyes, it can remain in our mind': qualitative evaluation findings suggest the ability of participatory video to reduce gender-based violence in conflict-affected settings. Health Education Research. 29: 690-701. PMID 24973224 DOI: 10.1093/her/cyu018  0.01
2014 Berkaliev Z, Devi S, Fasshauer GE, Hickernell FJ, Kartal O, Li X, McCray P, Whitney S, Zawojewski JS. Initiating a Programmatic Assessment Report Primus. 24: 403-420. DOI: 10.1080/10511970.2014.893939  0.01
2010 McCray P. How nanotechnology captured the public imagination. Nature. 467: 271. PMID 20844516 DOI: 10.1038/467271c  0.01
2005 McCray P. Management of operational risk by sovereign debt management agencies Advances in Risk Management of Government Debt. 2147483647: 67-88. DOI: 10.1787/9789264104433-6-en  0.01
2002 Kut V, Boasberg P, Sagar S, Miller S, Birdsall TC, Rey S, Martin J, Rogers M, Wicke RW, Cheung CS, He B, Chen K, Hovi MA, Dreher H, McCray P, et al. Integrative tumor board: Advanced breast cancer. Integrative Cancer Therapies. 1: 179-214. PMID 14664744 DOI: 10.1177/1534735402001002010  0.01
2001 Saiman L, Tabibi S, Starner TD, San Gabriel P, Winokur PL, Jia HP, McCray PB, Tack BF. Cathelicidin peptides inhibit multiply antibiotic-resistant pathogens from patients with cystic fibrosis. Antimicrobial Agents and Chemotherapy. 45: 2838-44. PMID 11557478 DOI: 10.1128/AAC.45.10.2838-2844.2001  0.01
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