Christoph Randak - Publications

Affiliations: 
2007-2009 University of Iowa, Iowa City, IA 

24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Paemka L, McCullagh BN, Abou Alaiwa MH, Stoltz DA, Dong Q, Randak CO, Gray RD, McCray PB. Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. PMID 28377087 DOI: 10.1016/j.jcf.2017.03.007  0.36
2016 Shah VS, Meyerholz DK, Tang XX, Reznikov L, Abou Alaiwa M, Ernst SE, Karp PH, Wohlford-Lenane CL, Heilmann KP, Leidinger MR, Allen PD, Zabner J, McCray PB, Ostedgaard LS, Stoltz DA, ... Randak CO, et al. Airway acidification initiates host defense abnormalities in cystic fibrosis mice. Science (New York, N.Y.). 351: 503-7. PMID 26823428 DOI: 10.1126/science.aad5589  0.6
2015 Dong Q, Ernst SE, Ostedgaard LS, Shah VS, Ver Heul AR, Welsh MJ, Randak CO. Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia. The Journal of Biological Chemistry. 290: 14140-53. PMID 25887396 DOI: 10.1074/jbc.M114.611616  0.6
2013 Randak CO, Dong Q, Ver Heul AR, Elcock AH, Welsh MJ. ATP and AMP mutually influence their interaction with the ATP-binding cassette (ABC) adenylate kinase cystic fibrosis transmembrane conductance regulator (CFTR) at separate binding sites. The Journal of Biological Chemistry. 288: 27692-701. PMID 23921386 DOI: 10.1074/jbc.M113.479675  0.6
2013 Reznikov LR, Dong Q, Chen JH, Moninger TO, Park JM, Zhang Y, Du J, Hildebrand MS, Smith RJ, Randak CO, Stoltz DA, Welsh MJ. CFTR-deficient pigs display peripheral nervous system defects at birth. Proceedings of the National Academy of Sciences of the United States of America. 110: 3083-8. PMID 23382208 DOI: 10.1073/pnas.1222729110  0.6
2013 Randak CO, Weinberger M. A child with progressive multiple tracheal diverticulae: a variation of the Mounier-Kuhn syndrome. Pediatric Pulmonology. 48: 841-3. PMID 22949127 DOI: 10.1002/ppul.22663  0.6
2012 Randak CO, Ver Heul AR, Welsh MJ. Demonstration of phosphoryl group transfer indicates that the ATP-binding cassette (ABC) transporter cystic fibrosis transmembrane conductance regulator (CFTR) exhibits adenylate kinase activity. The Journal of Biological Chemistry. 287: 36105-10. PMID 22948143 DOI: 10.1074/jbc.M112.408450  0.6
2008 Dong Q, Randak CO, Welsh MJ. A mutation in CFTR modifies the effects of the adenylate kinase inhibitor Ap5A on channel gating. Biophysical Journal. 95: 5178-85. PMID 18805924 DOI: 10.1529/biophysj.108.140897  0.6
2007 Randak CO, Welsh MJ. Role of CFTR's intrinsic adenylate kinase activity in gating of the Cl(-) channel. Journal of Bioenergetics and Biomembranes. 39: 473-9. PMID 17965924 DOI: 10.1007/s10863-007-9119-5  0.6
2007 Ostedgaard LS, Rogers CS, Dong Q, Randak CO, Vermeer DW, Rokhlina T, Karp PH, Welsh MJ. Processing and function of CFTR-DeltaF508 are species-dependent. Proceedings of the National Academy of Sciences of the United States of America. 104: 15370-5. PMID 17873061 DOI: 10.1073/pnas.0706974104  0.6
2005 Randak CO, Welsh MJ. Adenylate kinase activity in ABC transporters. The Journal of Biological Chemistry. 280: 34385-8. PMID 16100108 DOI: 10.1074/jbc.R500009200  0.6
2005 Randak CO, Welsh MJ. ADP inhibits function of the ABC transporter cystic fibrosis transmembrane conductance regulator via its adenylate kinase activity. Proceedings of the National Academy of Sciences of the United States of America. 102: 2216-20. PMID 15684079 DOI: 10.1073/pnas.0409787102  0.6
2005 Berger AL, Randak CO, Ostedgaard LS, Karp PH, Vermeer DW, Welsh MJ. Curcumin stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity. The Journal of Biological Chemistry. 280: 5221-6. PMID 15582996 DOI: 10.1074/jbc.M412972200  0.6
2004 Howell LD, Borchardt R, Kole J, Kaz AM, Randak C, Cohn JA. Protein kinase A regulates ATP hydrolysis and dimerization by a CFTR (cystic fibrosis transmembrane conductance regulator) domain. The Biochemical Journal. 378: 151-9. PMID 14602047 DOI: 10.1042/BJ20021428  0.6
2003 Randak C, Welsh MJ. An intrinsic adenylate kinase activity regulates gating of the ABC transporter CFTR. Cell. 115: 837-50. PMID 14697202 DOI: 10.1016/S0092-8674(03)00983-8  0.6
2003 Ostedgaard LS, Randak C, Rokhlina T, Karp P, Vermeer D, Ashbourne Excoffon KJ, Welsh MJ. Effects of C-terminal deletions on cystic fibrosis transmembrane conductance regulator function in cystic fibrosis airway epithelia. Proceedings of the National Academy of Sciences of the United States of America. 100: 1937-42. PMID 12578973 DOI: 10.1073/pnas.2627982100  0.6
2002 Ostedgaard LS, Zabner J, Vermeer DW, Rokhlina T, Karp PH, Stecenko AA, Randak C, Welsh MJ. CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo. Proceedings of the National Academy of Sciences of the United States of America. 99: 3093-8. PMID 11854474 DOI: 10.1073/pnas.261714599  0.6
2001 Dérand R, Bulteau-Pignoux L, Mettey Y, Zegarra-Moran O, Howell LD, Randak C, Galietta LJ, Cohn JA, Norez C, Romio L, Vierfond JM, Joffre M, Becq F. Activation of G551D CFTR channel with MPB-91: regulation by ATPase activity and phosphorylation. American Journal of Physiology. Cell Physiology. 281: C1657-66. PMID 11600430  0.6
2000 Randak C, Roschinger W, Rolinski B, Hadorn HB, Applegarth DA, Roscher AA. Three siblings with nonketotic hyperglycinaemia, mildly elevated plasma homocysteine concentrations and moderate methylmalonic aciduria. Journal of Inherited Metabolic Disease. 23: 520-2. PMID 10947210 DOI: 10.1023/A:1005667707355  0.6
1999 Randak C, Auerswald EA, Assfalg-Machleidt I, Reenstra WW, Machleidt W. Inhibition of ATPase, GTPase and adenylate kinase activities of the second nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator by genistein. The Biochemical Journal. 340: 227-35. PMID 10229679 DOI: 10.1042/0264-6021:3400227  0.6
1998 Randak C, Langnas AN, Kaufman SS, Phillips AD, Wisecarver JL, Hadorn HB, Vanderhoof JA. Pretransplant management and small bowel-liver transplantation in an infant with microvillus inclusion disease. Journal of Pediatric Gastroenterology and Nutrition. 27: 333-7. PMID 9740207 DOI: 10.1097/00005176-199809000-00012  0.6
1997 Randak C, Neth P, Auerswald EA, Eckerskorn C, Assfalg-Machleidt I, Machleidt W. A recombinant polypeptide model of the second nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator functions as an active ATPase, GTPase and adenylate kinase. Febs Letters. 410: 180-6. PMID 9237625 DOI: 10.1016/S0014-5793(97)00574-7  0.6
1996 Randak C, Neth P, Auerswald EA, Assfalg-Machleidt I, Roscher AA, Hadorn HB, Machleidt W. A recombinant polypeptide model of the second predicted nucleotide binding fold of the cystic fibrosis transmembrane conductance regulator is a GTP-binding protein. Febs Letters. 398: 97-100. PMID 8946960 DOI: 10.1016/S0014-5793(96)01217-3  0.6
1995 Randak C, Roscher AA, Hadorn HB, Assfalg-Machleidt I, Auerswald EA, Machleidt W. Expression and functional properties of the second predicted nucleotide binding fold of the cystic fibrosis transmembrane conductance regulator fused to glutathione-S-transferase. Febs Letters. 363: 189-94. PMID 7537226 DOI: 10.1016/0014-5793(95)00314-Y  0.6
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