Thomas E. Dick - Publications

Affiliations: 
Case Western Reserve University, Cleveland Heights, OH, United States 

86/315 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Barnett WH, Baekey DM, Paton JFR, Dick TE, Wehrwein EA, Molkov YI. Heartbeats entrain breathing via baroreceptor-mediated modulation of expiratory activity. Experimental Physiology. PMID 33749038 DOI: 10.1113/EP089365  0.654
2020 Barnett WH, Latash EM, Capps RE, Dick TE, Wehrwein EA, Molkov YI. Traube-Hering Waves Are Formed by Interaction of Respiratory Sinus Arrhythmia and Pulse Pressure Modulation in Healthy Males. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 32940558 DOI: 10.1152/Japplphysiol.00452.2020  0.628
2020 Hsieh YH, Litvin DG, Zaylor AR, Nethery DE, Dick TE, Jacono FJ. Brainstem inflammation modulates the ventilatory pattern and its variability after acute lung injury in rodents. The Journal of Physiology. PMID 32378188 DOI: 10.1113/Jp279177  0.382
2020 Dhingra RR, Dick TE, Furuya WI, Galán RF, Dutschmann M. Volumetric mapping of the functional neuroanatomy of the respiratory network in the perfused brainstem preparation of rats. The Journal of Physiology. PMID 32100293 DOI: 10.1113/Jp279605  0.368
2020 Guyenet P, Moraes DJ, Dick T. Decision letter: PreBötzinger complex neurons drive respiratory modulation of blood pressure and heart rate Elife. DOI: 10.7554/Elife.57288.Sa1  0.324
2020 Dhingra RR, Dick TE, Furuya WI, Galan RF, Dutschmann M. Volumetric mapping of the functional neuroanatomy of the brainstem respiratory network in the perfused brainstem preparation of rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03710  0.302
2020 He Z, Nethery D, Campanaro C, Dick TE, Jacono FJ, Hsieh YH. Cervical Vagal Nerve Stimulation Restores Ventilatory Pattern Variability in an E. Coli Sepsis Rodent Model. The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02963  0.31
2019 Dhingra RR, Furuya WI, Bautista TG, Dick TE, Galán RF, Dutschmann M. Increasing Local Excitability of Brainstem Respiratory Nuclei Reveals a Distributed Network Underlying Respiratory Motor Pattern Formation. Frontiers in Physiology. 10: 887. PMID 31396094 DOI: 10.3389/Fphys.2019.00887  0.427
2019 Young BP, Loparo KA, Dick TE, Jacono FJ. Ventilatory Pattern Variability as a Biometric for Severity of Acute Lung Injury in Rats. Respiratory Physiology & Neurobiology. PMID 30928542 DOI: 10.1016/J.Resp.2019.03.009  0.306
2018 Thungtong A, Knoch MF, Jacono FJ, Dick TE, Loparo KA. Periodicity: A Characteristic of Heart Rate Variability Modified by the Type of Mechanical Ventilation After Acute Lung Injury. Frontiers in Physiology. 9: 772. PMID 29971020 DOI: 10.3389/Fphys.2018.00772  0.333
2018 Litvin DG, Dick TE, Smith CB, Jacono FJ. Lung-injury depresses glutamatergic synaptic transmission in the nucleus tractus solitarii via discrete age-dependent mechanisms in neonatal rats. Brain, Behavior, and Immunity. PMID 29601943 DOI: 10.1016/J.Bbi.2018.03.031  0.35
2017 Cregg JM, Chu KA, Dick TE, Landmesser LT, Silver J. Phasic inhibition as a mechanism for generation of rapid respiratory rhythms. Proceedings of the National Academy of Sciences of the United States of America. PMID 29133427 DOI: 10.1073/Pnas.1711536114  0.36
2017 Romaniuk JR, Dick TE, Bruce EN, DiMarco AF, Kowalski KE. Bifurcation of the respiratory response to lung inflation in anesthetized dogs. Respiratory Physiology & Neurobiology. PMID 28698025 DOI: 10.1016/J.Resp.2017.06.010  0.313
2016 Dhingra RR, Dutschmann M, Galan RF, Dick TE. The Kölliker-Fuse nuclei regulate respiratory rhythm variability via a gain-control mechanism. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00238.2016. PMID 27974314 DOI: 10.1152/Ajpregu.00238.2016  0.403
2016 Yu H, Dhingra RR, Dick TE, Galan RF. Effects of Ion-Channel Noise on Neural Circuits: An Application to the Respiratory Pattern Generator to Investigate Breathing Variability. Journal of Neurophysiology. jn.00416.2016. PMID 27760817 DOI: 10.1152/Jn.00416.2016  0.344
2016 Dhingra RR, Dutschmann M, Dick TE. Blockade of dorsolateral pontine 5HT1A receptors destabilizes the respiratory rhythm in C57BL6/J wild-type mice. Respiratory Physiology & Neurobiology. 226: 110-4. PMID 26840837 DOI: 10.1016/J.Resp.2016.01.007  0.358
2015 Nuding SC, Segers LS, Iceman KE, O'Connor R, Dean JB, Bolser DC, Baekey DM, Dick TE, Shannon R, Morris KF, Lindsey BG. Functional connectivity in raphé-pontomedullary circuits supports active suppression of breathing during hypocapnic apnea. Journal of Neurophysiology. 114: 2162-86. PMID 26203111 DOI: 10.1152/Jn.00608.2015  0.419
2015 Dick TE, Dutschmann M, Feldman JL, Fong AY, Hülsmann S, Morris KM, Ramirez JM, Smith JC. Facts and challenges in respiratory neurobiology. Respiratory Physiology & Neurobiology. PMID 25644207 DOI: 10.1016/J.Resp.2015.01.014  0.33
2015 Hsieh YH, Jacono FJ, Siegel RE, Dick TE. Respiratory modulation of sympathetic activity is attenuated in adult rats conditioned with chronic hypobaric hypoxia. Respiratory Physiology & Neurobiology. 206: 53-60. PMID 25462835 DOI: 10.1016/J.Resp.2014.11.011  0.393
2014 Dick TE, Mims JR, Hsieh YH, Morris KF, Wehrwein EA. Increased cardio-respiratory coupling evoked by slow deep breathing can persist in normal humans. Respiratory Physiology & Neurobiology. 204: 99-111. PMID 25266396 DOI: 10.1016/J.Resp.2014.09.013  0.36
2014 Molkov YI, Zoccal DB, Baekey DM, Abdala AP, Machado BH, Dick TE, Paton JF, Rybak IA. Physiological and pathophysiological interactions between the respiratory central pattern generator and the sympathetic nervous system. Progress in Brain Research. 212: 1-23. PMID 25194190 DOI: 10.1016/B978-0-444-63488-7.00001-X  0.758
2014 Dick TE, Hsieh YH, Dhingra RR, Baekey DM, Galán RF, Wehrwein E, Morris KF. Cardiorespiratory coupling: common rhythms in cardiac, sympathetic, and respiratory activities. Progress in Brain Research. 209: 191-205. PMID 24746049 DOI: 10.1016/B978-0-444-63274-6.00010-2  0.398
2014 Dutschmann M, Bautista TG, Mörschel M, Dick TE. Learning to breathe: habituation of Hering-Breuer inflation reflex emerges with postnatal brainstem maturation. Respiratory Physiology & Neurobiology. 195: 44-9. PMID 24566392 DOI: 10.1016/J.Resp.2014.02.009  0.385
2013 Dhingra RR, Zhu Y, Jacono FJ, Katz DM, Galán RF, Dick TE. Decreased Hering-Breuer input-output entrainment in a mouse model of Rett syndrome. Frontiers in Neural Circuits. 7: 42. PMID 23565077 DOI: 10.3389/Fncir.2013.00042  0.364
2013 Kowalski KE, Hsieh YH, Dick TE, DiMarco AF. Diaphragm activation via high frequency spinal cord stimulation in a rodent model of spinal cord injury. Experimental Neurology. 247: 689-93. PMID 23499833 DOI: 10.1016/J.Expneurol.2013.03.006  0.334
2013 Molkov YI, Bacak BJ, Dick TE, Rybak IA. Control of breathing by interacting pontine and pulmonary feedback loops. Frontiers in Neural Circuits. 7: 16. PMID 23408512 DOI: 10.3389/Fncir.2013.00016  0.737
2013 Chung A, Fishman M, Dasenbrook EC, Loparo KA, Dick TE, Jacono FJ. Isoflurane and ketamine anesthesia have different effects on ventilatory pattern variability in rats. Respiratory Physiology & Neurobiology. 185: 659-64. PMID 23246800 DOI: 10.1016/J.Resp.2012.12.001  0.325
2012 Dutschmann M, Dick TE. Pontine mechanisms of respiratory control. Comprehensive Physiology. 2: 2443-69. PMID 23720253 DOI: 10.1002/Cphy.C100015  0.394
2012 Dick TE, Molkov YI, Nieman G, Hsieh YH, Jacono FJ, Doyle J, Scheff JD, Calvano SE, Androulakis IP, An G, Vodovotz Y. Linking Inflammation, Cardiorespiratory Variability, and Neural Control in Acute Inflammation via Computational Modeling. Frontiers in Physiology. 3: 222. PMID 22783197 DOI: 10.3389/Fphys.2012.00222  0.655
2011 Jacono FJ, Dick TE. Variability, measuring the spice of life. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 351-2. PMID 21719724 DOI: 10.1152/Japplphysiol.00786.2011  0.3
2011 Jacono FJ, Mayer CA, Hsieh YH, Wilson CG, Dick TE. Lung and brainstem cytokine levels are associated with breathing pattern changes in a rodent model of acute lung injury. Respiratory Physiology & Neurobiology. 178: 429-38. PMID 21569869 DOI: 10.1016/J.Resp.2011.04.022  0.333
2011 Dhingra RR, Jacono FJ, Fishman M, Loparo KA, Rybak IA, Dick TE. Vagal-dependent nonlinear variability in the respiratory pattern of anesthetized, spontaneously breathing rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 272-84. PMID 21527661 DOI: 10.1152/Japplphysiol.91196.2008  0.592
2011 Prabha K, Balan KV, Martin RJ, Lamanna JC, Haxhiu MA, Dick TE. Chronic intermittent hypoxia-induced augmented cardiorespiratory outflow mediated by vasopressin-V₁A receptor signaling in the medulla. Advances in Experimental Medicine and Biology. 701: 319-25. PMID 21445804 DOI: 10.1007/978-1-4419-7756-4_43  0.382
2010 Dick TE, Pilowsky PM. Respiratory Physiology & Neurobiology. Foreword. Respiratory Physiology & Neurobiology. 174: 1-3. PMID 20933107 DOI: 10.1016/J.Resp.2010.09.017  0.378
2010 Galán RF, Dick TE, Baekey DM. Analysis and modeling of ensemble recordings from respiratory pre-motor neurons indicate changes in functional network architecture after acute hypoxia. Frontiers in Computational Neuroscience. 4. PMID 20890445 DOI: 10.3389/Fncom.2010.00131  0.42
2010 Baekey DM, Molkov YI, Paton JF, Rybak IA, Dick TE. Effect of baroreceptor stimulation on the respiratory pattern: insights into respiratory-sympathetic interactions. Respiratory Physiology & Neurobiology. 174: 135-45. PMID 20837166 DOI: 10.1016/J.Resp.2010.09.006  0.763
2010 Kc P, Dick TE. Modulation of cardiorespiratory function mediated by the paraventricular nucleus. Respiratory Physiology & Neurobiology. 174: 55-64. PMID 20708107 DOI: 10.1016/J.Resp.2010.08.001  0.373
2010 Morris KF, Nuding SC, Segers LS, Baekey DM, Shannon R, Lindsey BG, Dick TE. Respiratory and Mayer wave-related discharge patterns of raphé and pontine neurons change with vagotomy. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 189-202. PMID 20360432 DOI: 10.1152/Japplphysiol.01324.2009  0.432
2010 Kc P, Balan KV, Tjoe SS, Martin RJ, Lamanna JC, Haxhiu MA, Dick TE. Increased vasopressin transmission from the paraventricular nucleus to the rostral medulla augments cardiorespiratory outflow in chronic intermittent hypoxia-conditioned rats. The Journal of Physiology. 588: 725-40. PMID 20051497 DOI: 10.1113/Jphysiol.2009.184580  0.338
2010 Dunin-Barkowski WL, Lovering AT, Orem JM, Baekey DM, Dick TE, Rybak IA, Morris KF, O'Connor R, Nuding SC, Shannon R, Lindsey BG. L-plotting-A method for visual analysis of physiological experimental and modeling multi-component data Neurocomputing. 74: 328-336. DOI: 10.1016/J.Neucom.2010.03.015  0.593
2009 Dutschmann M, Mörschel M, Rybak IA, Dick TE. Learning to breathe: control of the inspiratory-expiratory phase transition shifts from sensory- to central-dominated during postnatal development in rats. The Journal of Physiology. 587: 4931-48. PMID 19703965 DOI: 10.1113/Jphysiol.2009.174599  0.616
2009 Dick TE, Baekey DM, Paton JF, Lindsey BG, Morris KF. Cardio-respiratory coupling depends on the pons. Respiratory Physiology & Neurobiology. 168: 76-85. PMID 19643216 DOI: 10.1016/J.Resp.2009.07.009  0.437
2009 McMullan S, Dick TE, Farnham MM, Pilowsky PM. Effects of baroreceptor activation on respiratory variability in rat. Respiratory Physiology & Neurobiology. 166: 80-6. PMID 19429523 DOI: 10.1016/J.Resp.2009.02.006  0.416
2009 Julien C, Parkes MJ, Tzeng SY, Sin PY, Ainslie PN, van de Borne P, Fortrat JO, Custaud MA, Gharib C, Porta A, Vallais F, Baselli G, Pagani M, Lucini D, Hughson RL, ... ... Dick TE, et al. Comments on point:counterpoint: respiratory sinus arrhythmia is due to a central mechanism vs. respiratory sinus arrhythmia is due to the baroreflex mechanism. Journal of Applied Physiology (Bethesda, Md. : 1985). 106: 1745-9. PMID 19414628 DOI: 10.1152/Japplphysiol.00196.2009  0.353
2009 Nuding SC, Segers LS, Baekey DM, Dick TE, Solomon IC, Shannon R, Morris KF, Lindsey BG. Pontine-ventral respiratory column interactions through raphe circuits detected using multi-array spike train recordings. Journal of Neurophysiology. 101: 2943-60. PMID 19297509 DOI: 10.1152/Jn.91305.2008  0.376
2009 Baekey DM, Dick TE, Galán RF. Spike synchronization is population specific in the respiratory pattern generator Bmc Neuroscience. 10: P248. DOI: 10.1186/1471-2202-10-S1-P248  0.359
2008 Alilain WJ, Li X, Horn KP, Dhingra R, Dick TE, Herlitze S, Silver J. Light-induced rescue of breathing after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11862-70. PMID 19005051 DOI: 10.1523/Jneurosci.3378-08.2008  0.33
2008 Rybak IA, O'Connor R, Ross A, Shevtsova NA, Nuding SC, Segers LS, Shannon R, Dick TE, Dunin-Barkowski WL, Orem JM, Solomon IC, Morris KF, Lindsey BG. Reconfiguration of the pontomedullary respiratory network: a computational modeling study with coordinated in vivo experiments. Journal of Neurophysiology. 100: 1770-99. PMID 18650310 DOI: 10.1152/Jn.90416.2008  0.66
2008 Segers LS, Nuding SC, Dick TE, Shannon R, Baekey DM, Solomon IC, Morris KF, Lindsey BG. Functional connectivity in the pontomedullary respiratory network. Journal of Neurophysiology. 100: 1749-69. PMID 18632881 DOI: 10.1152/Jn.90414.2008  0.408
2008 Dick TE, Shannon R, Lindsey BG, Nuding SC, Segers LS, Baekey DM, Morris KF. Pontine respiratory-modulated activity before and after vagotomy in decerebrate cats. The Journal of Physiology. 586: 4265-82. PMID 18599543 DOI: 10.1113/Jphysiol.2008.152108  0.46
2008 Baekey DM, Dick TE, Paton JF. Pontomedullary transection attenuates central respiratory modulation of sympathetic discharge, heart rate and the baroreceptor reflex in the in situ rat preparation. Experimental Physiology. 93: 803-16. PMID 18344259 DOI: 10.1113/Expphysiol.2007.041400  0.43
2008 Hsieh YH, Dick TE, Siegel RE. Adaptation to hypobaric hypoxia involves GABA A receptors in the pons. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 294: R549-57. PMID 18056985 DOI: 10.1152/Ajpregu.00339.2007  0.302
2007 Dick TE, Hsieh YH, Wang N, Prabhakar N. Acute intermittent hypoxia increases both phrenic and sympathetic nerve activities in the rat. Experimental Physiology. 92: 87-97. PMID 17138622 DOI: 10.1113/Expphysiol.2006.035758  0.414
2007 Prabhakar NR, Dick TE, Nanduri J, Kumar GK. Systemic, cellular and molecular analysis of chemoreflex-mediated sympathoexcitation by chronic intermittent hypoxia. Experimental Physiology. 92: 39-44. PMID 17124274 DOI: 10.1113/Expphysiol.2006.036434  0.365
2007 Romaniuk JR, Dick TE, Kowalski KE, Dimarco AF. Effects of pulse lung inflation on chest wall expiratory motor activity. Journal of Applied Physiology (Bethesda, Md. : 1985). 102: 485-91. PMID 16959914 DOI: 10.1152/Japplphysiol.00130.2006  0.333
2007 Subramanian S, Dostal J, Erokwu B, Han F, Dick TE, Strohl KP. Domperidone and ventilatory behavior: Sprague-Dawley versus Brown Norway rats. Respiratory Physiology & Neurobiology. 155: 22-8. PMID 16781202 DOI: 10.1016/J.Resp.2006.04.002  0.311
2007 Baekey DM, Paton JF, Dick TE. Baroreceptor receptive Bötzinger expiratory (E) neurons in the ventrolateral medulla of the in‐situ perfused rat The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A562-C  0.307
2007 Lindsey BG, Ross A, O'Connor R, Morris KF, Nuding SC, Segers LS, Shannon R, Dick TE, Dunin‐Barkowski WL, Orem JM, Solomon IC, Rybak IA. Modulation and reconfiguration of the pontomedullary respiratory network: A computational modeling study The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A559-A  0.595
2005 Prabhakar NR, Peng YJ, Jacono FJ, Kumar GK, Dick TE. Cardiovascular alterations by chronic intermittent hypoxia: importance of carotid body chemoreflexes. Clinical and Experimental Pharmacology & Physiology. 32: 447-9. PMID 15854156 DOI: 10.1111/J.1440-1681.2005.04209.X  0.361
2005 Dick TE, Shannon R, Lindsey BG, Nuding SC, Segers LS, Baekey DM, Morris KF. Arterial pulse modulated activity is expressed in respiratory neural output. Journal of Applied Physiology (Bethesda, Md. : 1985). 99: 691-8. PMID 15761086 DOI: 10.1152/Japplphysiol.01124.2004  0.44
2004 Rybak IA, Shevtsova NA, Paton JF, Dick TE, St-John WM, Mörschel M, Dutschmann M. Modeling the ponto-medullary respiratory network. Respiratory Physiology & Neurobiology. 143: 307-19. PMID 15519563 DOI: 10.1016/J.Resp.2004.03.020  0.67
2004 Hsieh YH, Siegel RE, Dick TE. Pontine GABAergic pathways: role and plasticity in the hypoxic ventilatory response. Respiratory Physiology & Neurobiology. 143: 141-53. PMID 15519551 DOI: 10.1016/J.Resp.2004.03.016  0.321
2004 Dick TE, Hsieh YH, Morrison S, Coles SK, Prabhakar N. Entrainment pattern between sympathetic and phrenic nerve activities in the Sprague-Dawley rat: Hypoxia-evoked sympathetic activity during expiration American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 286: R1121-R1128. PMID 15001434 DOI: 10.1152/Ajpregu.00485.2003  0.441
2004 Dick TE, Morris KF. Quantitative analysis of cardiovascular modulation in respiratory neural activity. The Journal of Physiology. 556: 959-70. PMID 14978205 DOI: 10.1113/Jphysiol.2003.060418  0.45
2003 Morris KF, Baekey DM, Nuding SC, Dick TE, Shannon R, Lindsey BG. Invited review: Neural network plasticity in respiratory control. Journal of Applied Physiology (Bethesda, Md. : 1985). 94: 1242-52. PMID 12571145 DOI: 10.1152/Japplphysiol.00715.2002  0.427
2002 Subramanian S, Han F, Erokwu BO, Dick TE, Strohl KP. Do genetic factors influence the Dejours phenomenon? Advances in Experimental Medicine and Biology. 499: 209-14. PMID 11729879 DOI: 10.1007/978-1-4615-1375-9_32  0.34
2001 Peng Y, Kline DD, Dick TE, Prabhakar NR. Chronic intermittent hypoxia enhances carotid body chemoreceptor response to low oxygen. Advances in Experimental Medicine and Biology. 499: 33-8. PMID 11729902 DOI: 10.1007/978-1-4615-1375-9_5  0.321
2001 van Lunteren E, Dick TE. Heterogeneity within geniohyoid motor unit subpopulations in firing patterns during breathing. Respiration Physiology. 124: 23-33. PMID 11084200 DOI: 10.1016/S0034-5687(00)00182-1  0.372
2000 Dick TE, Coles SK. Ventrolateral pons mediates short-term depression of respiratory frequency after brief hypoxia. Respiration Physiology. 121: 87-100. PMID 10963767 DOI: 10.1016/S0034-5687(00)00121-3  0.39
1997 Jodkowski JS, Coles SK, Dick TE. Prolongation in expiration evoked from ventrolateral pons of adult rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 82: 377-81. PMID 9049713 DOI: 10.1152/Jappl.1997.82.2.377  0.364
1997 Coles SK, Dick TE. Neurones in the ventrolateral pons are required for post-hypoxic frequency decline in rats. The Journal of Physiology. 79-94. PMID 8951713 DOI: 10.1113/Jphysiol.1996.Sp021751  0.387
1995 Oku Y, Dick TE. Paradoxical phase response at late expiration by superior laryngeal nerve stimulation. Neuroreport. 6: 379-83. PMID 7756633 DOI: 10.1097/00001756-199501000-00037  0.383
1994 Jodkowski JS, Coles SK, Dick TE. A 'pneumotaxic centre' in rats. Neuroscience Letters. 172: 67-72. PMID 8084539 DOI: 10.1016/0304-3940(94)90664-5  0.307
1994 Dick TE, Bellingham MC, Richter DW. Pontine respiratory neurons in anesthetized cats. Brain Research. 636: 259-69. PMID 8012810 DOI: 10.1016/0006-8993(94)91025-1  0.389
1993 Oku Y, Dick TE, Cherniack NS. Phase-dependent dynamic responses of respiratory motor activities following perturbation of the cycle in the cat. The Journal of Physiology. 461: 321-37. PMID 8350268 DOI: 10.1113/Jphysiol.1993.Sp019516  0.322
1993 Dick TE, Oku Y, Romaniuk JR, Cherniack NS. Interaction between central pattern generators for breathing and swallowing in the cat. The Journal of Physiology. 465: 715-30. PMID 8229859 DOI: 10.1113/Jphysiol.1993.Sp019702  0.384
1992 Dick TE, Haxhiu MA, Cherniack NS. Salivary secretion elicited by activation of the parabrachial nuclei in the cat. Journal of the Autonomic Nervous System. 39: 19-27. PMID 1629522 DOI: 10.1016/0165-1838(92)90247-E  0.347
1992 van Lunteren E, Dick TE. Intrinsic properties of pharyngeal and diaphragmatic respiratory motoneurons and muscles. Journal of Applied Physiology (Bethesda, Md. : 1985). 73: 787-800. PMID 1400039 DOI: 10.1152/Jappl.1992.73.3.787  0.33
1990 Dick TE. Artifactual averaged 'twitch tension' waveforms resulting from synchronized activity: recording from feline diaphragmatic motor units. Neuroscience Letters. 114: 57-62. PMID 2381574 DOI: 10.1016/0304-3940(90)90428-C  0.313
1989 van Lunteren E, Dick TE. Motor unit regulation of mammalian pharyngeal dilator muscle activity. The Journal of Clinical Investigation. 84: 577-85. PMID 2760202 DOI: 10.1172/Jci114201  0.348
1989 Dick TE, Kelsen SG. Relationship between diaphragmatic activation and twitch tension to superimposed electrical stimulation in the cat. Respiration Physiology. 76: 337-45. PMID 2501843 DOI: 10.1016/0034-5687(89)90074-1  0.353
1988 van Lunteren E, Prabhakar NR, Cherniack NS, Haxhiu MA, Dick TE. Inhibition of expiratory muscle EMG and motor unit activity during augmented breaths in cats. Respiration Physiology. 72: 303-14. PMID 3406552 DOI: 10.1016/0034-5687(88)90089-8  0.327
1988 van Lunteren E, Cherniack NS, Dick TE. Upper airway pressure receptors alter expiratory muscle EMG and motor unit firing. Journal of Applied Physiology (Bethesda, Md. : 1985). 65: 210-7. PMID 3403465 DOI: 10.1152/Jappl.1988.65.1.210  0.301
1985 Orem J, Osorio I, Brooks E, Dick TE. Activity of respiratory neurons during NREM sleep. Journal of Neurophysiology. 54: 1144-1156. PMID 4078611 DOI: 10.1152/Jn.1985.54.5.1144  0.336
1984 Orem J, Dick T. Consistency and signal strength of respiratory neuronal activity. Journal of Neurophysiology. 50: 1098-107. PMID 6644361 DOI: 10.1152/Jn.1983.50.5.1098  0.413
1983 Dick TE, Parmeggiani PL, Orem J. Intercostal muscle activity during sleep in the cat: an augmentation of expiratory activity. Respiration Physiology. 50: 255-65. PMID 7156535 DOI: 10.1016/0034-5687(82)90022-6  0.303
Low-probability matches (unlikely to be authored by this person)
1998 Coles SK, Ernsberger P, Dick TE. A role for NMDA receptors in posthypoxic frequency decline in the rat. The American Journal of Physiology. 274: R1546-55. PMID 9608007 DOI: 10.1152/Ajpregu.1998.274.6.R1546  0.3
1993 Supinski GS, Dick T, Stofan D, DiMarco AF. Effects of intraphrenic injection of potassium on diaphragm activation Journal of Applied Physiology. 74: 1186-1194. DOI: 10.1152/Jappl.1993.74.3.1186  0.298
2007 Morris KF, Lindsey BG, Baekey DM, Nuding SC, Segers LS, Shannon R, Connor REO, Dick TE. Frequency and time series analysis of a 0.1 Hz rhythm in pontine and raphe cardio‐respiratory related neurons suggest coherence with blood pressure Mayer waves The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A562-B  0.297
2020 Litvin DG, Denstaedt SJ, Borkowski LF, Nichols NL, Dick TE, Smith CB, Jacono FJ. Peripheral-to-central immune communication at the area postrema glial-barrier following bleomycin-induced sterile lung injury in adult rats. Brain, Behavior, and Immunity. PMID 32097765 DOI: 10.1016/J.Bbi.2020.02.006  0.297
2013 Zhu Y, Hsieh YH, Dhingra RR, Dick TE, Jacono FJ, Galán RF. Quantifying interactions between real oscillators with information theory and phase models: application to cardiorespiratory coupling. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 87: 022709. PMID 23496550 DOI: 10.1103/Physreve.87.022709  0.296
2012 Namas R, Zamora R, Namas R, An G, Doyle J, Dick TE, Jacono FJ, Androulakis IP, Nieman GF, Chang S, Billiar TR, Kellum JA, Angus DC, Vodovotz Y. Sepsis: Something old, something new, and a systems view. Journal of Critical Care. 27: 314.e1-11. PMID 21798705 DOI: 10.1016/J.Jcrc.2011.05.025  0.294
2002 Dick TE, Dutschmann M, Paton JF. Post-hypoxic frequency decline characterized in the rat working heart brainstem preparation. Advances in Experimental Medicine and Biology. 499: 247-54. PMID 11729886 DOI: 10.1007/978-1-4615-1375-9_39  0.293
2018 Warren PM, Steiger SC, Dick TE, MacFarlane PM, Alilain WJ, Silver J. Rapid and robust restoration of breathing long after spinal cord injury. Nature Communications. 9: 4843. PMID 30482901 DOI: 10.1038/S41467-018-06937-0  0.289
2012 Fishman M, Jacono FJ, Park S, Jamasebi R, Thungtong A, Loparo KA, Dick TE. A method for analyzing temporal patterns of variability of a time series from Poincare plots. Journal of Applied Physiology (Bethesda, Md. : 1985). 113: 297-306. PMID 22556398 DOI: 10.1152/Japplphysiol.01377.2010  0.289
2011 Alilain WJ, Horn KP, Hu H, Dick TE, Silver J. Functional regeneration of respiratory pathways after spinal cord injury. Nature. 475: 196-200. PMID 21753849 DOI: 10.1038/Nature10199  0.288
2013 Scheff JD, Mavroudis PD, Foteinou PT, An G, Calvano SE, Doyle J, Dick TE, Lowry SF, Vodovotz Y, Androulakis IP. A multiscale modeling approach to inflammation: A case study in human endotoxemia Journal of Computational Physics. 244: 279-289. DOI: 10.1016/J.Jcp.2012.09.024  0.288
1984 Dick TE, Parmeggiani PL, Orem JM. Intercostal muscle activity of the cat in the curled, semiprone sleeping posture Respiration Physiology. 56: 385-394. PMID 6473948 DOI: 10.1016/0034-5687(84)90072-0  0.287
2013 Loria CJ, Stevens AM, Crummy E, Casadesus G, Jacono FJ, Dick TE, Siegel RE. Respiratory and behavioral dysfunction following loss of the GABAA receptor α4 subunit. Brain and Behavior. 3: 104-13. PMID 23533098 DOI: 10.1002/Brb3.122  0.286
2010 Jacono FJ, de Georgia MA, Wilson CG, Dick TE, Loparo KA. Data acquisition and complex systems analysis in critical care: Developing the intensive care unit of the future Journal of Healthcare Engineering. 1: 337-355. DOI: 10.1260/2040-2295.1.3.337  0.286
1981 Orem J, Dick T, Norris P. Laryngeal and diaphragmatic responses to airway occlusion in sleep and wakefulness. Electroencephalography and Clinical Neurophysiology. 50: 151-64. PMID 6159183 DOI: 10.1016/0013-4694(80)90332-6  0.282
2004 Gonsenhauser I, Wilson CG, Han F, Strohl KP, Dick TE. Strain differences in murine ventilatory behavior persist after urethane anesthesia. Journal of Applied Physiology (Bethesda, Md. : 1985). 97: 888-94. PMID 15333626 DOI: 10.1152/Japplphysiol.01346.2003  0.28
1996 Martin RJ, DiFiore JM, Davis RL, Novak WJ, Coles SK, Dick TE, Miller MJ. DISSOCIATION IN THE RESPONSES OF TIDAL VOLUME AND RESPIRATORY FREQUENCY TO HYPOXIA IN PRETERM INFANTS. † 2020 Pediatric Research. 39: 339-339. DOI: 10.1203/00006450-199604001-02044  0.277
2002 Han F, Subramanian S, Dick TE, Dreshaj IA, Strohl KP. Ventilatory behavior after hypoxia in C57BL/6J and A/J mice. Journal of Applied Physiology (Bethesda, Md. : 1985). 91: 1962-70. PMID 11641331 DOI: 10.1152/Jappl.2001.91.5.1962  0.273
1998 Coles SK, Ernsberger P, Dick TE. Post-hypoxic frequency decline does not depend on alpha2-adrenergic receptors in the adult rat. Brain Research. 794: 267-73. PMID 9622648 DOI: 10.1016/S0006-8993(98)00234-0  0.272
1996 Anderson CA, Dick TE, Orem J. Respiratory responses to tracheobronchial stimulation during sleep and wakefulness in the adult cat. Sleep. 19: 472-478. PMID 8865504 DOI: 10.1093/Sleep/19.6.472  0.271
2002 Subramanian S, Erokwu B, Han F, Dick TE, Strohl KP. L-NAME differentially alters ventilatory behavior in Sprague-Dawley and Brown Norway rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 93: 984-9. PMID 12183494 DOI: 10.1152/Japplphysiol.00677.2001  0.27
1998 Martin RJ, DiFiore JM, Jana L, Davis RL, Miller MJ, Coles SK, Dick TE. Persistence of the biphasic ventilatory response to hypoxia in preterm infants. The Journal of Pediatrics. 132: 960-4. PMID 9627586 DOI: 10.1016/S0022-3476(98)70391-9  0.269
2000 Dick TE, Mitchell GS. Mechanisms and variables determining the cardiopulmonary responses to hypoxia Respiration Physiology. 121: 85-6. PMID 10963766 DOI: 10.1016/S0034-5687(00)00142-0  0.269
2009 Foglyano RM, Kaffashi F, Dick TE, Loparo KA, Wilson CG. Quantifying the complexity of neural network output using entropy measures Bmc Neuroscience. 10. DOI: 10.1186/1471-2202-10-S1-P322  0.269
2013 Dick TE, Hsieh Y, Litvin D, Nethery DE, Zhu Y, Galan RF, Wilson CG, Loparo KA, Jacono FJ. Development of brainstem inflammation correlates with uncoupling of the cardiorespiratory system in an endotoxemic rodent model Journal of Critical Care. 28: e34. DOI: 10.1016/J.Jcrc.2013.07.020  0.268
2020 Clifford C, Campanaro C, Tackett S, Horton K, Nethery D, Hsieh Y, Jacono F, Dick T. Estrus Cycle Stages Differentially Alter Ventilatory Pattern Variability (VPV) in Septic Female Rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05680  0.265
2020 Tackett S, Guo F, Clifford C, Campanaro C, Nethery D, Horton K, Fletcher D, Kaffashi F, Hsieh Y, Bonfield T, Loparo K, Dick T, Jacono F. Translational Study Tracking Dynamic Changes in Cardiac Pattern Variability and Systemic Inflammation in Critically Ill Patients The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04085  0.265
2003 Price ER, Han F, Dick TE, Strohl KP. 7-nitroindazole and posthypoxic ventilatory behavior in the A/J and C57BL/6J mouse strains. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 1097-104. PMID 12909599 DOI: 10.1152/Japplphysiol.00166.2003  0.26
1990 Lunteren Ev, Salomone RJ, Manubay P, Supinski GS, Dick TE. Contractile and endurance properties of geniohyoid and diaphragm muscles. Journal of Applied Physiology. 69: 1992-1997. PMID 2076992 DOI: 10.1152/Jappl.1990.69.6.1992  0.259
2020 Campanaro C, Clifford C, Tackett S, Horton K, Nethery D, Hsieh Y, Dick T, Jacono F. Breathing Pattern Differs Between Male and Female Rats in Escherichia coli Induced Septicemia The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05565  0.257
2020 Horton KA, Clifford C, Campanaro C, Tackett S, Nethery D, Dick T, Jacono F, Strohl K. Modulation of Cannabinoid System and Proinflammatory Cytokine mRNAs in Central and Peripheral Tissue in a Rodent E. coli Sepsis Model The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05872  0.254
1984 Light KE, Dick TE, Hughes MJ. Central and peripheral receptors in guinea-pigs exposed to simulated high altitude Neuropharmacology. 23: 189-195. PMID 6325990 DOI: 10.1016/S0028-3908(84)80013-1  0.251
2016 Gillombardo CB, Darrah R, Dick TE, Moore M, Kong N, Decker MJ, Han F, Yamauchi M, Dutschmann M, Azzam S, Strohl KP. C57BL/6J Mouse Apolipoprotein A2 Gene is Deterministic for Apnea. Respiratory Physiology & Neurobiology. PMID 27756649 DOI: 10.1016/J.Resp.2016.10.006  0.245
2013 Denstaedt S, Litvin D, Hsieh Y, Nethery D, Dick T, Wilson C, Jacono F. Increased Brainstem IL-1β Expression Persists Seven Days After Lung Injury in Rats Chest. 144: 467A. DOI: 10.1378/Chest.1705003  0.241
1990 Dick TE, van Lunteren E. Fiber subtype distribution of pharyngeal dilator muscles and diaphragm in the cat. Journal of Applied Physiology (Bethesda, Md. : 1985). 68: 2237-40. PMID 2141833 DOI: 10.1152/Jappl.1990.68.5.2237  0.24
1987 Berger AJ, Dick TE. Connectivity of slowly adapting pulmonary stretch receptors with dorsal medullary respiratory neurons. Journal of Neurophysiology. 58: 1259-74. PMID 3437333 DOI: 10.1152/Jn.1987.58.6.1259  0.237
2012 Friedman L, Dick TE, Jacono FJ, Loparo KA, Yeganeh A, Fishman M, Wilson CG, Strohl KP. Cardio-ventilatory coupling in young healthy resting subjects. Journal of Applied Physiology (Bethesda, Md. : 1985). 112: 1248-57. PMID 22267392 DOI: 10.1152/Japplphysiol.01424.2010  0.236
2014 Abu Jawdeh EG, Martin RJ, Dick TE, Walsh MC, Di Fiore JM. The effect of red blood cell transfusion on intermittent hypoxemia in ELBW infants. Journal of Perinatology : Official Journal of the California Perinatal Association. 34: 921-5. PMID 24921411 DOI: 10.1038/Jp.2014.115  0.236
2007 Strohl K, Yamauchi M, Dick T. Loop Gain and Sleep Disordered Breathing Current Respiratory Medicine Reviews. 3: 85-92. DOI: 10.2174/157339807779941794  0.233
1995 Anderson CA, Dick TE, Orem J. Swallowing in sleep and wakefulness in adult cats. Sleep. 18: 325-9. PMID 7676164 DOI: 10.1093/Sleep/18.5.325  0.232
2016 Dhingra RR, Dutschmann M, Dick TE. Blockade of dorsolateral pontine 5HT1A receptors destabilizes the respiratory rhythm in C57BL6/J wild-type mice Respiratory Physiology and Neurobiology. 226: 110-114. DOI: 10.1016/j.resp.2016.01.007  0.232
2001 van Lunteren E, Moyer M, Dick TE. Modulation of diaphragm action potentials by K(+) channel blockers. Respiration Physiology. 124: 217-30. PMID 11173076 DOI: 10.1016/S0034-5687(00)00198-5  0.231
2008 Dick TE, Shannon R, Lindsey BG, Nuding SC, Segers LS, Baekey DM. Erratum: (Journal of Physiology (2008)) The Journal of Physiology. 586. DOI: 10.1113/Jphysiol.2008.163055  0.231
2013 Montano MM, Desjardins CL, Doughman YQ, Hsieh YH, Hu Y, Bensinger HM, Wang C, Stelzer JE, Dick TE, Hoit BD, Chandler MP, Yu X, Watanabe M. Inducible re-expression of HEXIM1 causes physiological cardiac hypertrophy in the adult mouse. Cardiovascular Research. 99: 74-82. PMID 23585471 DOI: 10.1093/Cvr/Cvt086  0.23
2023 Campanaro CK, Nethery DE, Guo F, Kaffashi F, Loparo KA, Jacono FJ, Dick TE, Hsieh YH. Dynamics of ventilatory pattern variability and Cardioventilatory Coupling during systemic inflammation in rats. Frontiers in Network Physiology. 3: 1038531. PMID 37583625 DOI: 10.3389/fnetp.2023.1038531  0.226
2017 Vandendriessche B, Abas M, Dick TE, Loparo KA, Jacono FJ. A Framework for Patient State Tracking by Classifying Multiscalar Physiologic Waveform Features. Ieee Transactions On Bio-Medical Engineering. 64: 2890-2900. PMID 28328498 DOI: 10.1109/Tbme.2017.2684244  0.221
2022 Horton KA, Campanaro CK, Clifford C, Nethery DE, Strohl KP, Jacono FJ, Dick TE. Cannabinoid Receptor mRNA Expression in Central and Peripheral Tissues in a Rodent Model of Peritonitis. Cannabis and Cannabinoid Research. PMID 35446129 DOI: 10.1089/can.2021.0085  0.218
2017 Vandendriessche B, Abas M, Nethery D, Dick T, Loparo K, Jacono F. Trajectory of multiscalar variability dynamics in a physiologic state space correlates with mortality in septic patients Journal of Critical Care. 38: 367-368. DOI: 10.1016/J.Jcrc.2016.11.026  0.212
1992 Oku Y, Dick TE. Phase resetting of the respiratory cycle before and after unilateral pontine lesion in cat. Journal of Applied Physiology (Bethesda, Md. : 1985). 72: 721-30. PMID 1559953 DOI: 10.1152/JAPPL.1992.72.2.721  0.211
1987 Holtman JR, Dick TE, Berger AJ. Serotonin-mediated excitation of recurrent laryngeal and phrenic motoneurons evoked by stimulation of the raphe obscurus. Brain Research. 417: 12-20. PMID 3620972 DOI: 10.1016/0006-8993(87)90174-0  0.175
1986 Holtman JR, Dick TE, Berger AJ. Involvement of serotonin in the excitation of phrenic motoneurons evoked by stimulation of the raphe obscurus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 1185-93. PMID 3701414 DOI: 10.1523/Jneurosci.06-04-01185.1986  0.175
1988 Jodkowski JS, Viana F, Dick TE, Berger AJ. Repetitive firing properties of phrenic motoneurons in the cat. Journal of Neurophysiology. 60: 687-702. PMID 3171647 DOI: 10.1152/Jn.1988.60.2.687  0.166
1987 Dick TE, Kong FJ, Berger AJ. Correlation of recruitment order with axonal conduction velocity for supraspinally driven diaphragmatic motor units. Journal of Neurophysiology. 57: 245-59. PMID 3559674 DOI: 10.1152/Jn.1987.57.1.245  0.161
1987 Jodkowski JS, Viana F, Dick TE, Berger AJ. Electrical properties of phrenic motoneurons in the cat: correlation with inspiratory drive. Journal of Neurophysiology. 58: 105-24. PMID 3039077 DOI: 10.1152/Jn.1987.58.1.105  0.156
2020 Sarathy JP, Ganapathy US, Zimmerman MD, Dartois V, Gengenbacher M, Dick T. TBAJ-876, a 3,5-Dialkoxypyridine Analogue of Bedaquiline, Is Active against Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy. 64. PMID 31964791 DOI: 10.1128/AAC.02404-19  0.15
1992 van Lunteren E, Dick TE. Breath-to-breath variability in hypoglossal motor unit firing Respiration Physiology. 89: 37-46. DOI: 10.1016/0034-5687(92)90069-9  0.143
1985 Dick TE, Berger AJ. Axonal projections of single bulbospinal inspiratory neurons revealed by spike-triggered averaging and antidromic activation. Journal of Neurophysiology. 53: 1590-603. PMID 2989449 DOI: 10.1152/Jn.1985.53.6.1590  0.133
2021 Fridianto KT, Li M, Hards K, Negatu DA, Cook GM, Dick T, Lam Y, Go ML. Functionalized Dioxonaphthoimidazoliums: A Redox Cycling Chemotype with Potent Bactericidal Activities against . Journal of Medicinal Chemistry. PMID 34706190 DOI: 10.1021/acs.jmedchem.1c01383  0.133
2013 Dick TE, Dhingra RR, Hsieh YH, Fishman M, Kaffashi F, Loparo KA, Wilson CG, Jacono FJ. Analysis of ventilatory pattern variability Complex Systems and Computational Biology Approaches to Acute Inflammation. 79-99. DOI: 10.1007/978-1-4614-8008-2_5  0.133
2009 Low KL, Rao PS, Shui G, Bendt AK, Pethe K, Dick T, Wenk MR. Triacylglycerol utilization is required for regrowth of in vitro hypoxic nonreplicating Mycobacterium bovis bacillus Calmette-Guerin. Journal of Bacteriology. 191: 5037-43. PMID 19525349 DOI: 10.1128/Jb.00530-09  0.13
2022 Fridianto KT, Gunawan GA, Hards K, Sarathy JP, Cook GM, Dick T, Go ML, Lam Y. Alkyltriphenylphosphonium turns naphthoquinoneimidazoles into potent membrane depolarizers against . Rsc Medicinal Chemistry. 13: 1605-1613. PMID 36545436 DOI: 10.1039/d2md00251e  0.129
2024 Dartois V, Dick T. Therapeutic developments for tuberculosis and nontuberculous mycobacterial lung disease. Nature Reviews. Drug Discovery. PMID 38418662 DOI: 10.1038/s41573-024-00897-5  0.12
2024 Kola G, Clifford CW, Campanaro CK, Dhingra RR, Dutschmann M, Jacono FJ, Dick TE. Peritoneal sepsis caused by Escherichia coli triggers brainstem inflammation and alters the function of sympatho-respiratory control circuits. Journal of Neuroinflammation. 21: 45. PMID 38331902 DOI: 10.1186/s12974-024-03025-7  0.12
2024 Lang M, Ganapathy US, Mann L, Seidel RW, Goddard R, Erdmann F, Dick T, Richter A. Synthesis and in vitro Metabolic Stability of Sterically Shielded Antimycobacterial Phenylalanine Amides. Chemmedchem. 19: e202300593. PMID 38329388 DOI: 10.1002/cmdc.202300593  0.12
2022 Kaya F, Ernest JP, LoMauro K, Gengenbacher M, Madani A, Aragaw WW, Zimmerman MD, Sarathy JP, Alvarez N, Daudelin I, Wang H, Lanni F, Weiner DM, Via LE, Barry CE, ... ... Dick T, et al. A rabbit model to study antibiotic penetration at the site of infection for non-tuberculous mycobacterial lung disease: macrolide case study. Antimicrobial Agents and Chemotherapy. aac0221221. PMID 35099272 DOI: 10.1128/aac.02212-21  0.12
2023 Negatu DA, González Del Río R, Cacho-Izquierdo M, Barros-Aguirre D, Lelievre J, Rullas J, Casado P, Ganapathy US, Zimmerman MD, Gengenbacher M, Dartois V, Dick T. Activity of Oral Tebipenem-Avibactam in a Mouse Model of Mycobacterium abscessus Lung Infection. Antimicrobial Agents and Chemotherapy. e0145922. PMID 36688684 DOI: 10.1128/aac.01459-22  0.118
2023 Xie M, Ganapathy US, Lan T, Osiecki P, Sarathy JP, Dartois V, Aldrich CC, Dick T. ADP-ribosylation-resistant rifabutin analogs show improved bactericidal activity against drug-tolerant in caseum surrogate. Antimicrobial Agents and Chemotherapy. e0038123. PMID 37493373 DOI: 10.1128/aac.00381-23  0.115
2023 Ganapathy US, Lan T, Dartois V, Aldrich CC, Dick T. Blocking ADP-ribosylation expands the anti-mycobacterial spectrum of rifamycins. Microbiology Spectrum. e0190023. PMID 37681986 DOI: 10.1128/spectrum.01900-23  0.113
2021 Ganapathy US, Del Rio RG, Cacho-Izquierdo M, Ortega F, Lelièvre J, Barros-Aguirre D, Lindman M, Dartois V, Gengenbacher M, Dick T. A Leucyl-tRNA Synthetase Inhibitor with Broad-Spectrum Anti-Mycobacterial Activity. Antimicrobial Agents and Chemotherapy. PMID 33558292 DOI: 10.1128/AAC.02420-20  0.112
2019 Sarathy JP, Ragunathan P, Cooper CB, Upton AM, Grüber G, Dick T. TBAJ-876 displays Bedaquiline-like mycobactericidal potency without retaining the parental drug's uncoupler activity. Antimicrobial Agents and Chemotherapy. PMID 31712198 DOI: 10.1128/AAC.01540-19  0.111
2012 Gurumurthy M, Mukherjee T, Dowd CS, Singh R, Niyomrattanakit P, Tay JA, Nayyar A, Lee YS, Cherian J, Boshoff HI, Dick T, Barry CE, Manjunatha UH. Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles. The Febs Journal. 279: 113-25. PMID 22023140 DOI: 10.1111/j.1742-4658.2011.08404.x  0.111
2009 Kim P, Kang S, Boshoff HI, Jiricek J, Collins M, Singh R, Manjunatha UH, Niyomrattanakit P, Zhang L, Goodwin M, Dick T, Keller TH, Dowd CS, Barry CE. Structure-activity relationships of antitubercular nitroimidazoles. 2. Determinants of aerobic activity and quantitative structure-activity relationships. Journal of Medicinal Chemistry. 52: 1329-44. PMID 19209893 DOI: 10.1021/jm801374t  0.111
2021 Ganapathy US, Gengenbacher M, Dick T. Epetraborole Is Active against Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy. 65: e0115621. PMID 34280020 DOI: 10.1128/AAC.01156-21  0.111
2019 Sarathy JP, Gruber G, Dick T. Re-Understanding the Mechanisms of Action of the Anti-Mycobacterial Drug Bedaquiline. Antibiotics (Basel, Switzerland). 8. PMID 31835707 DOI: 10.3390/antibiotics8040261  0.11
2011 Cherian J, Choi I, Nayyar A, Manjunatha UH, Mukherjee T, Lee YS, Boshoff HI, Singh R, Ha YH, Goodwin M, Lakshminarayana SB, Niyomrattanakit P, Jiricek J, Ravindran S, Dick T, et al. Structure-activity relationships of antitubercular nitroimidazoles. 3. Exploration of the linker and lipophilic tail of ((s)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl)-(4-trifluoromethoxybenzyl)amine (6-amino PA-824). Journal of Medicinal Chemistry. 54: 5639-59. PMID 21755942 DOI: 10.1021/jm1010644  0.109
2017 Mukherjee D, Wu ML, Teo JWP, Dick T. Vancomycin and clarithromycin show synergy against Mycobacterium abscessus in vitro. Antimicrobial Agents and Chemotherapy. PMID 28923867 DOI: 10.1128/AAC.01298-17  0.108
2014 Lakshminarayana SB, Boshoff HI, Cherian J, Ravindran S, Goh A, Jiricek J, Nanjundappa M, Nayyar A, Gurumurthy M, Singh R, Dick T, Blasco F, Barry CE, Ho PC, Manjunatha UH. Pharmacokinetics-pharmacodynamics analysis of bicyclic 4-nitroimidazole analogs in a murine model of tuberculosis. Plos One. 9: e105222. PMID 25141257 DOI: 10.1371/journal.pone.0105222  0.107
2013 Dick T, Hsieh Y. Hypoxia-induced augmented cardiorespiratory responses Autonomic Neuroscience. 177: 32. DOI: 10.1016/j.autneu.2013.05.051  0.107
2018 Aziz DB, Teo JWP, Dartois V, Dick T. Teicoplanin - Tigecycline Combination Shows Synergy Against . Frontiers in Microbiology. 9: 932. PMID 29867841 DOI: 10.3389/fmicb.2018.00932  0.107
2002 Boon C, Dick T. Mycobacterium bovis BCG response regulator essential for hypoxic dormancy. Journal of Bacteriology. 184: 6760-7. PMID 12446625 DOI: 10.1128/JB.184.24.6760-6767.2002  0.107
2022 Lan T, Ganapathy US, Sharma S, Ahn YM, Zimmerman M, Molodtsov V, Hegde P, Gengenbacher M, Ebright RH, Dartois V, Freundlich JS, Dick T, Aldrich CC. Redesign of Rifamycin Antibiotics to Overcome ADP-Ribosylation-Mediated Resistance. Angewandte Chemie (International Ed. in English). e202211498. PMID 36222275 DOI: 10.1002/anie.202211498  0.106
2018 Blanc L, Sarathy JP, Alvarez Cabrera N, O'Brien P, Dias-Freedman I, Mina M, Sacchettini J, Savic RM, Gengenbacher M, Podell BK, Prideaux B, Ioerger T, Dick T, Dartois V. Impact of immunopathology on the antituberculous activity of pyrazinamide. The Journal of Experimental Medicine. PMID 30018074 DOI: 10.1084/Jem.20180518  0.106
2021 Ganapathy US, Lan T, Krastel P, Lindman M, Zimmerman MD, Ho H, Sarathy JP, Evans JC, Dartois V, Aldrich CC, Dick T. Blocking bacterial naphthohydroquinone oxidation and ADP-ribosylation improves activity of rifamycins against . Antimicrobial Agents and Chemotherapy. AAC0097821. PMID 34228543 DOI: 10.1128/AAC.00978-21  0.104
1988 Dick TE, Viana F, Berger AJ. Electrophysiological determination of the axonal projections of single dorsal respiratory group neurons to the cervical spinal cord of cat. Brain Research. 454: 31-9. PMID 3409013 DOI: 10.1016/0006-8993(88)90800-1  0.103
2019 Kamariah N, Ragunathan P, Shin J, Saw WG, Wong CF, Dick T, Grüber G. Unique structural and mechanistic properties of mycobacterial F-ATP synthases: Implications for drug design. Progress in Biophysics and Molecular Biology. PMID 31743686 DOI: 10.1016/j.pbiomolbio.2019.11.006  0.102
2017 Yamada Y, Dick T. Mycobacterial Caseinolytic Protease Gene Regulator ClgR Is a Substrate of Caseinolytic Protease. Msphere. 2. PMID 28317028 DOI: 10.1128/mSphere.00338-16  0.101
2020 Hotra A, Ragunathan P, Ng PS, Seankongsuk P, Harikishore A, Sarathy JP, Geok SW, Lakshmanan U, Sae-Lao P, Kalia NP, Shin J, Kalyanasundaram R, Anbarasu S, Parthasarathy K, Pradeep CN, ... ... Dick T, et al. Discovery of a novel Mycobacterial F-ATP synthase inhibitor and its potency in combination with diarylquinolines. Angewandte Chemie (International Ed. in English). PMID 32337801 DOI: 10.1002/Anie.202002546  0.1
2020 Li M, Phua ZY, Xi Y, Xu Z, Nyantakyi SA, Li W, Jackson MC, Wong MW, Lam Y, Chng SS, Go ML, Dick T. Potency Increase of Spiroketal Analogs of Membrane Inserting Indolyl Mannich Base Antimycobacterials Is Due to Acquisition of MmpL3 Inhibition. Acs Infectious Diseases. PMID 32413266 DOI: 10.1021/acsinfecdis.0c00121  0.1
2018 Daniel-Wayman S, Abate G, Barber DL, Bermudez LE, Coler RN, Cynamon MH, Daley CL, Davidson RM, Dick T, Floto RA, Henkle E, Holland SM, Jackson M, Lee RE, Nuermberger EL, et al. Advancing Translational Science for Pulmonary NTM Infections: A Roadmap for Research. American Journal of Respiratory and Critical Care Medicine. PMID 30428263 DOI: 10.1164/Rccm.201807-1273Pp  0.099
2024 Ragunathan P, Sae-Lao P, Hamela C, Alcaraz M, Krah A, Poh WH, Ern Pee CJ, Hou Lim AY, Rice SA, Pethe K, Bond PJ, Dick T, Kremer L, Bates RW, Grüber G. High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against non-tuberculous mycobacteria in vitro and in vivo. The Journal of Biological Chemistry. 105618. PMID 38176652 DOI: 10.1016/j.jbc.2023.105618  0.098
2021 Hegde P, Boshoff HIM, Rusman Y, Aragaw WW, Salomon CE, Dick T, Aldrich CC. Reinvestigation of the structure-activity relationships of isoniazid. Tuberculosis (Edinburgh, Scotland). 129: 102100. PMID 34116482 DOI: 10.1016/j.tube.2021.102100  0.098
2023 Negatu DA, Shin SJ, Kim SY, Jhun BW, Dartois V, Dick T. Oral β-lactam pairs for the treatment of Mycobacterium avium complex pulmonary disease. The Journal of Infectious Diseases. PMID 38150401 DOI: 10.1093/infdis/jiad591  0.098
2019 Zhong W, Pasunooti K, Balamkundu S, Wong YH, Nah Q, Gadi V, Gnanakalai S, Chionh YH, McBee ME, Gopal P, Lim SH, Olivier N, Buurman E, Dick T, Liu CF, et al. Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism. Journal of Medicinal Chemistry. PMID 31442049 DOI: 10.1021/acs.jmedchem.9b00582  0.098
2018 Shetty A, Xu Z, Lakshmanan U, Hill J, Choong ML, Chng SS, Yamada Y, Poulsen A, Dick T, Gengenbacher M. Novel Acetamide Indirectly Targets Mycobacterial Transporter MmpL3 by Proton Motive Force Disruption. Frontiers in Microbiology. 9: 2960. PMID 30564212 DOI: 10.3389/fmicb.2018.02960  0.098
2021 Ragunathan P, Cole M, Latka C, Aragaw WW, Hegde P, Shin J, Subramanian Manimekalai MS, Rishikesan S, Aldrich CC, Dick T, Grüber G. PanD Structure-Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor. Acs Chemical Biology. PMID 33984234 DOI: 10.1021/acschembio.1c00131  0.097
2017 Aziz DB, Low JL, Wu ML, Gengenbacher M, Teo JW, Dartois V, Dick T. Rifabutin Is Active Against Mycobacterium abscessus Complex. Antimicrobial Agents and Chemotherapy. PMID 28396540 DOI: 10.1128/AAC.00155-17  0.097
2015 Wu ML, Tan J, Dick T. Eagle Effect in Non-replicating Persister Mycobacteria. Antimicrobial Agents and Chemotherapy. PMID 26349831 DOI: 10.1128/AAC.01476-15  0.096
2021 Dhingra RR, Furuya WI, Dick TE, Dutschmann M. Response to: The post-inspiratory complex (PiCo), what is the evidence? The Journal of Physiology. 599: 361-362. PMID 33197048 DOI: 10.1113/JP280958  0.095
2017 Yang T, Moreira W, Nyantakyi SA, Chen H, Aziz DB, Go ML, Dick T. Amphiphilic Indole Derivatives as Antimycobacterial Agents: Structure-Activity Relationships and Membrane Targeting Properties. Journal of Medicinal Chemistry. PMID 28290692 DOI: 10.1021/acs.jmedchem.6b01530  0.094
2022 Hegde PV, Aragaw WW, Cole MS, Jachak G, Ragunathan P, Sharma S, Harikishore A, Grüber G, Dick T, Aldrich CC. Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents. Bioorganic & Medicinal Chemistry. 74: 117046. PMID 36228522 DOI: 10.1016/j.bmc.2022.117046  0.094
1979 Larsen PR, Dick TE, Markovitz BP, Kaplan MM, Gard TG. Inhibition of intrapituitary thyroxine to 3.5.3'-triiodothyronine conversion prevents the acute suppression of thyrotropin release by thyroxine in hypothyroid rats. The Journal of Clinical Investigation. 64: 117-28. PMID 447848 DOI: 10.1172/JCI109430  0.094
2010 Gengenbacher M, Rao SP, Pethe K, Dick T. Nutrient-starved, non-replicating Mycobacterium tuberculosis requires respiration, ATP synthase and isocitrate lyase for maintenance of ATP homeostasis and viability. Microbiology (Reading, England). 156: 81-7. PMID 19797356 DOI: 10.1099/Mic.0.033084-0  0.094
2023 Aragaw WW, Negatu DA, Bungard CJ, Dartois VA, Marrouni AE, Nickbarg EB, Olsen DB, Warrass R, Dick T. Pharmacological validation of dihydrofolate reductase as a drug target in . Antimicrobial Agents and Chemotherapy. e0071723. PMID 38018963 DOI: 10.1128/aac.00717-23  0.094
2008 Rao SP, Alonso S, Rand L, Dick T, Pethe K. The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 105: 11945-50. PMID 18697942 DOI: 10.1073/Pnas.0711697105  0.093
2022 Harikishore A, Saw WG, Ragunathan P, Litty D, Dick T, Müller V, Grüber G. Mutational Analysis of Mycobacterial F-ATP Synthase Subunit δ Leads to a Potent δ Enzyme Inhibitor. Acs Chemical Biology. 17: 529-535. PMID 35148057 DOI: 10.1021/acschembio.1c00766  0.093
2016 Hotra A, Suter M, Biuković G, Ragunathan P, Kundu S, Dick T, Grüber G. Deletion of a unique loop in the mycobacterial F-ATP synthase γ subunit sheds light in its inhibitory role in ATP hydrolysis driven H(+) -pumping. The Febs Journal. PMID 26996828 DOI: 10.1111/febs.13715  0.093
2020 Aziz DB, Go ML, Dick T. Rifabutin Suppresses Inducible Clarithromycin Resistance in by Blocking Induction of and . Antibiotics (Basel, Switzerland). 9. PMID 32050554 DOI: 10.3390/antibiotics9020072  0.093
2020 Chong S, Manimekalai MSS, Sarathy JP, Williams ZC, Harold LK, Cook GM, Dick T, Pethe K, Bates RW, Grüber G. Anti-tuberculosis activity of the anti-malaria cytochrome bcc oxidase inhibitor SCR0911. Acs Infectious Diseases. PMID 32092260 DOI: 10.1021/Acsinfecdis.9B00408  0.092
2016 Moreira W, Aziz DB, Dick T. Boromycin Kills Mycobacterial Persisters without Detectable Resistance. Frontiers in Microbiology. 7: 199. PMID 26941723 DOI: 10.3389/fmicb.2016.00199  0.091
2013 Murima P, de Sessions PF, Lim V, Naim AN, Bifani P, Boshoff HI, Sambandamurthy VK, Dick T, Hibberd ML, Schreiber M, Rao SP. Exploring the mode of action of bioactive compounds by microfluidic transcriptional profiling in mycobacteria. Plos One. 8: e69191. PMID 23935951 DOI: 10.1371/journal.pone.0069191  0.091
2017 Ragunathan P, Sielaff H, Sundararaman L, Biuković G, Subramanian Manimekalai MS, Singh D, Kundu S, Wohland T, Frasch W, Dick T, Grüber G. The uniqueness of subunit α of mycobacterial F-ATP synthases: An evolutionary variant for niche adaptation. The Journal of Biological Chemistry. PMID 28495884 DOI: 10.1074/Jbc.M117.784959  0.09
2012 Cellitti SE, Shaffer J, Jones DH, Mukherjee T, Gurumurthy M, Bursulaya B, Boshoff HI, Choi I, Nayyar A, Lee YS, Cherian J, Niyomrattanakit P, Dick T, Manjunatha UH, Barry CE, et al. Structure of Ddn, the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis involved in bioreductive activation of PA-824. Structure (London, England : 1993). 20: 101-12. PMID 22244759 DOI: 10.1016/j.str.2011.11.001  0.089
2022 Saw WG, Leow CY, Harikishore A, Shin J, Cole MS, Aragaw WW, Ragunathan P, Hegde P, Aldrich CC, Dick T, Grüber G. Structural and Mechanistic Insights into Aspartate Decarboxylase PanD and a Pyrazinoic Acid-Derived Inhibitor. Acs Infectious Diseases. PMID 35731701 DOI: 10.1021/acsinfecdis.2c00133  0.089
2016 Wu ML, Chan CL, Dick T. Rel Is Required for Morphogenesis of Resting Cells in Mycobacterium smegmatis. Frontiers in Microbiology. 7: 1390. PMID 27630635 DOI: 10.3389/fmicb.2016.01390  0.088
2019 Lindman M, Dick T. Bedaquiline Eliminates Bactericidal Activity of β-Lactams against Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy. 63. PMID 31182531 DOI: 10.1128/AAC.00827-19  0.088
2023 Stampolaki M, Malwal SR, Alvarez-Cabrera N, Gao Z, Moniruzzaman M, Babii SO, Naziris N, Rey-Cibati A, Valladares-Delgado M, Turcu AL, Baek KH, Phan TN, Lee H, Alcaraz M, Watson S, ... ... Dick T, et al. Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against and Malaria Parasites. Acs Infectious Diseases. PMID 36706233 DOI: 10.1021/acsinfecdis.2c00537  0.088
2019 Dick T, Shin SJ, Koh WJ, Dartois V, Gengenbacher M. Rifabutin is active against in mice. Antimicrobial Agents and Chemotherapy. PMID 31767722 DOI: 10.1128/AAC.01943-19  0.087
2019 Gopal P, Grüber G, Dartois V, Dick T. Pharmacological and Molecular Mechanisms Behind the Sterilizing Activity of Pyrazinamide. Trends in Pharmacological Sciences. 40: 930-940. PMID 31704175 DOI: 10.1016/j.tips.2019.10.005  0.087
2010 Pethe K, Sequeira PC, Agarwalla S, Rhee K, Kuhen K, Phong WY, Patel V, Beer D, Walker JR, Duraiswamy J, Jiricek J, Keller TH, Chatterjee A, Tan MP, Ujjini M, ... ... Dick T, et al. A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy. Nature Communications. 1: 57. PMID 20975714 DOI: 10.1038/Ncomms1060  0.087
2008 Gengenbacher M, Xu T, Niyomrattanakit P, Spraggon G, Dick T. Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis. Fems Microbiology Letters. 287: 128-35. PMID 18680522 DOI: 10.1111/j.1574-6968.2008.01302.x  0.086
2021 Ganapathy US, Del Río RG, Cacho-Izquierdo M, Ortega F, Lelièvre J, Barros-Aguirre D, Aragaw WW, Zimmerman MD, Lindman M, Dartois V, Gengenbacher M, Dick T. A Mycobacterium tuberculosis NBTI DNA Gyrase Inhibitor Is Active against Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy. 65: e0151421. PMID 34606340 DOI: 10.1128/AAC.01514-21  0.086
2023 Malwal SR, Mazurek B, Ko J, Xie P, Barnes C, Varvitsiotis C, Zimmerman MD, Olatunji S, Lee J, Xie M, Sarathy J, Caffrey M, Strynadka NCJ, Dartois V, Dick T, et al. Investigation into the Mechanism of Action of the Tuberculosis Drug Candidate SQ109 and Its Metabolites and Analogues in Mycobacteria. Journal of Medicinal Chemistry. PMID 37235809 DOI: 10.1021/acs.jmedchem.3c00398  0.086
2012 Mak PA, Rao SP, Ping Tan M, Lin X, Chyba J, Tay J, Ng SH, Tan BH, Cherian J, Duraiswamy J, Bifani P, Lim V, Lee BH, Ling Ma N, Beer D, ... ... Dick T, et al. A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating Mycobacterium tuberculosis. Acs Chemical Biology. 7: 1190-7. PMID 22500615 DOI: 10.1021/Cb2004884  0.086
2020 Negatu DA, Gengenbacher M, Dartois V, Dick T. Indole Propionic Acid, an Unusual Antibiotic Produced by the Gut Microbiota, With Anti-inflammatory and Antioxidant Properties. Frontiers in Microbiology. 11: 575586. PMID 33193190 DOI: 10.3389/fmicb.2020.575586  0.086
2019 Saw WG, Wu ML, Ragunathan P, Biuković G, Lau AM, Shin J, Harikishore A, Cheung CY, Hards K, Sarathy JP, Bates RW, Cook GM, Dick T, Grüber G. Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis. Scientific Reports. 9: 16759. PMID 31727946 DOI: 10.1038/s41598-019-53107-3  0.084
2022 Girardini M, Ferlenghi F, Annunziato G, Degiacomi G, Papotti B, Marchi C, Sammartino JC, Rasheed SS, Contini A, Pasca MR, Vacondio F, Evans JC, Dick T, Müller R, Costantino G, et al. Expanding the knowledge around antitubercular 5-(2-aminothiazol-4-yl)isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. European Journal of Medicinal Chemistry. 245: 114916. PMID 36399878 DOI: 10.1016/j.ejmech.2022.114916  0.084
2022 Beuchel A, Robaa D, Negatu DA, Madani A, Alvarez N, Zimmerman MD, Richter A, Mann L, Hoenke S, Csuk R, Dick T, Imming P. Structure-Activity Relationship of Anti- Piperidine-4-carboxamides, a New Class of NBTI DNA Gyrase Inhibitors. Acs Medicinal Chemistry Letters. 13: 417-427. PMID 35300094 DOI: 10.1021/acsmedchemlett.1c00549  0.084
2019 Ganapathy US, Dartois V, Dick T. Repositioning rifamycins for Mycobacterium abscessus lung disease. Expert Opinion On Drug Discovery. 14: 867-878. PMID 31195849 DOI: 10.1080/17460441.2019.1629414  0.083
2023 Negatu DA, Aragaw WW, Cangialosi J, Dartois V, Dick T. Side-by-Side Profiling of Oxazolidinones to Estimate the Therapeutic Window against Mycobacterial Infections. Antimicrobial Agents and Chemotherapy. e0165522. PMID 36920191 DOI: 10.1128/aac.01655-22  0.083
2018 Joon S, Priya R, Lavanya S, Nartey W, Kundu S, Manimekalai MSS, Bogdanović N, Dick T, Grüber G. The NMR solution structure of Mycobacterium tuberculosis F-ATP synthase subunit ε provides new insight into energy coupling inside the rotary engine. The Febs Journal. PMID 29360236 DOI: 10.1111/febs.14392  0.082
2017 Moreira W, Santhanakrishnan S, Dymock BW, Dick T. Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome. Frontiers in Microbiology. 8: 746. PMID 28496439 DOI: 10.3389/fmicb.2017.00746  0.081
2018 Nyantakyi SA, Li M, Gopal P, Zimmerman M, Dartois V, Gengenbacher M, Dick T, Go ML. Indolyl Azaspiroketal Mannich Bases Are Potent Anti-mycobacterial Agents with Selective Membrane Permeabilizing Effects and In Vivo Activity. Journal of Medicinal Chemistry. PMID 29894180 DOI: 10.1021/acs.jmedchem.8b00777  0.081
2017 Moreira W, Santhanakrishnan S, Ngan GJ, Low CB, Sangthongpitag K, Poulsen A, Dymock BW, Dick T. Towards Selective Mycobacterial ClpP1P2 Inhibitors with Reduced Activity Against the Human Proteasome. Antimicrobial Agents and Chemotherapy. PMID 28193668 DOI: 10.1128/AAC.02307-16  0.081
2012 Boon C, Dick T. How Mycobacterium tuberculosis goes to sleep: the dormancy survival regulator DosR a decade later. Future Microbiology. 7: 513-8. PMID 22439727 DOI: 10.2217/fmb.12.14  0.081
2015 Moreira W, Ngan GJ, Low JL, Poulsen A, Chia BC, Ang MJ, Yap A, Fulwood J, Lakshmanan U, Lim J, Khoo AY, Flotow H, Hill J, Raju RM, Rubin EJ, ... Dick T, et al. Target mechanism-based whole-cell screening identifies bortezomib as an inhibitor of caseinolytic protease in mycobacteria. Mbio. 6: e00253-15. PMID 25944857 DOI: 10.1128/Mbio.00253-15  0.08
2021 Aragaw WW, Lee BM, Yang X, Zimmerman MD, Gengenbacher M, Dartois V, Chui WK, Jackson CJ, Dick T. Potency boost of a dihydrofolate reductase inhibitor by multienzyme FH-dependent reduction. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34161270 DOI: 10.1073/pnas.2025172118  0.08
2020 Dick T. Rifabutin: A Repurposing Candidate for Lung Disease. Frontiers in Microbiology. 11: 371. PMID 32174907 DOI: 10.3389/fmicb.2020.00371  0.08
2019 Sarathy JP, Ragunathan P, Shin J, Cooper CB, Upton AM, Grüber G, Dick T. TBAJ-876 retains Bedaquiline's activity against subunit c and ϵ of F-ATP synthase. Antimicrobial Agents and Chemotherapy. PMID 31358589 DOI: 10.1128/AAC.01191-19  0.079
2012 Franzblau SG, DeGroote MA, Cho SH, Andries K, Nuermberger E, Orme IM, Mdluli K, Angulo-Barturen I, Dick T, Dartois V, Lenaerts AJ. Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 92: 453-88. PMID 22940006 DOI: 10.1016/J.Tube.2012.07.003  0.079
2016 Moreira W, Lim JJ, Yeo SY, Ramanujulu PM, Dymock BW, Dick T. Fragment-Based Whole Cell Screen Delivers Hits against M. tuberculosis and Non-tuberculous Mycobacteria. Frontiers in Microbiology. 7: 1392. PMID 27656168 DOI: 10.3389/fmicb.2016.01392  0.079
2020 Dhingra RR, Furuya WI, Dick TE, Dutschmann M. Response to: The post‐inspiratory complex (PiCo), what is the evidence? The Journal of Physiology. 599: 361-362. DOI: 10.1113/JP280958  0.079
2017 Low JL, Wu ML, Aziz DB, Laleu B, Dick T. Screening of TB Actives for Activity against Nontuberculous Mycobacteria Delivers High Hit Rates. Frontiers in Microbiology. 8: 1539. PMID 28861054 DOI: 10.3389/fmicb.2017.01539  0.078
2022 Ragunathan P, Dick T, Grüber G. Anti-Mycobacterium abscessus Activity of Tuberculosis F-ATP Synthase Inhibitor GaMF1. Antimicrobial Agents and Chemotherapy. e0001822. PMID 35481752 DOI: 10.1128/aac.00018-22  0.078
2016 Wu ML, Gengenbacher M, Dick T. Mild Nutrient Starvation Triggers the Development of a Small-Cell Survival Morphotype in Mycobacteria. Frontiers in Microbiology. 7: 947. PMID 27379076 DOI: 10.3389/fmicb.2016.00947  0.077
2022 Mann L, Ganapathy US, Abdelaziz R, Lang M, Zimmerman MD, Dartois V, Dick T, Richter A. Profiling of the Synthetic RNA Polymerase Inhibitor MMV688845 against Mycobacterium abscessus. Microbiology Spectrum. e0276022. PMID 36377951 DOI: 10.1128/spectrum.02760-22  0.077
2021 Negatu DA, Beuchel A, Madani A, Alvarez N, Chen C, Aragaw WW, Zimmerman MD, Laleu B, Gengenbacher M, Dartois V, Imming P, Dick T. Piperidine-4-carboxamides target DNA gyrase in . Antimicrobial Agents and Chemotherapy. PMID 34001512 DOI: 10.1128/AAC.00676-21  0.076
2013 Zheng J, Rubin EJ, Bifani P, Mathys V, Lim V, Au M, Jang J, Nam J, Dick T, Walker JR, Pethe K, Camacho LR. para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 288: 23447-56. PMID 23779105 DOI: 10.1074/Jbc.M113.475798  0.076
1988 Dick TE, Jodkowski JS, Viana F, Berger AJ. Projections and terminations of single respiratory axons in the cervical spinal cord of cat. Brain Research. 449: 201-12. PMID 2456126 DOI: 10.1016/0006-8993(88)91038-4  0.075
2020 Wong CF, Lau AM, Harikishore A, Saw WG, Joon S, Ragunathan P, Bhushan S, Fong Ngan CS, Sze SK, Bates RW, Dick T, Grüber G. A systematic assessment of mycobacterial F -ATPase subunit ε's role in latent ATPase hydrolysis. The Febs Journal. PMID 32525613 DOI: 10.1111/febs.15440  0.075
2018 Shetty A, Dick T. Mycobacterial Cell Wall Synthesis Inhibitors Cause Lethal ATP Burst. Frontiers in Microbiology. 9: 1898. PMID 30158918 DOI: 10.3389/fmicb.2018.01898  0.075
2016 Koh JJ, Zou H, Mukherjee D, Lin S, Lim F, Tan JK, Tan DZ, Stocker BL, Timmer MS, Corkran HM, Lakshminarayanan R, Tan DT, Cao D, Beuerman RW, Dick T, et al. Amphiphilic xanthones as a potent chemical entity of anti-mycobacterial agents with membrane-targeting properties. European Journal of Medicinal Chemistry. 123: 684-703. PMID 27517813 DOI: 10.1016/j.ejmech.2016.07.068  0.075
2019 Negatu DA, Yamada Y, Xi Y, Go ML, Zimmerman M, Ganapathy U, Dartois V, Gengenbacher M, Dick T. Gut Microbiota Metabolite Indole Propionic Acid Targets Tryptophan Biosynthesis in . Mbio. 10. PMID 30914514 DOI: 10.1128/mBio.02781-18  0.075
2022 Shin J, Harikishore A, Wong CF, Ragunathan P, Dick T, Grüber G. Atomic solution structure of Mycobacterium abscessus F-ATP synthase subunit ε and identification of Ep1MabF1 as a targeted inhibitor. The Febs Journal. PMID 35612822 DOI: 10.1111/febs.16536  0.074
2018 Chen C, Gardete S, Jansen RS, Shetty A, Dick T, Rhee KY, Dartois V. Verapamil targets membrane energetics in. Antimicrobial Agents and Chemotherapy. PMID 29463541 DOI: 10.1128/AAC.02107-17  0.073
2023 Ragunathan P, Shuyi Ng P, Singh S, Poh WH, Litty D, Kalia NP, Larsson S, Harikishore A, Rice SA, Ingham PW, Müller V, Moraski G, Miller MJ, Dick T, Pethe K, et al. GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876. Microbiology Spectrum. e0228223. PMID 37982630 DOI: 10.1128/spectrum.02282-23  0.073
2019 Safi H, Gopal P, Lingaraju S, Ma S, Levine C, Dartois V, Yee M, Li L, Blanc L, Ho Liang HP, Husain S, Hoque M, Soteropoulos P, Rustad T, Sherman DR, ... Dick T, et al. Phase variation in produces transiently heritable drug tolerance. Proceedings of the National Academy of Sciences of the United States of America. PMID 31488707 DOI: 10.1073/Pnas.1907631116  0.073
2022 Wong CF, Saw WG, Basak S, Sano M, Ueno H, Kerk HW, Litty D, Ragunathan P, Dick T, Müller V, Noji H, Grüber G. Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors. Antimicrobial Agents and Chemotherapy. 66: e0105622. PMID 36445139 DOI: 10.1128/aac.01056-22  0.073
2010 Low KL, Shui G, Natter K, Yeo WK, Kohlwein SD, Dick T, Rao SP, Wenk MR. Lipid droplet-associated proteins are involved in the biosynthesis and hydrolysis of triacylglycerol in Mycobacterium bovis bacillus Calmette-Guerin. The Journal of Biological Chemistry. 285: 21662-70. PMID 20452973 DOI: 10.1074/jbc.M110.135731  0.072
2022 Madani A, Negatu DA, El Marrouni A, Miller RR, Boyce CW, Murgolo N, Bungard CJ, Zimmerman MD, Dartois V, Gengenbacher M, Olsen DB, Dick T. Activity of Tricyclic Pyrrolopyrimidine Gyrase B Inhibitor against Mycobacterium abscessus. Antimicrobial Agents and Chemotherapy. e0066922. PMID 36005813 DOI: 10.1128/aac.00669-22  0.072
2007 Shui G, Bendt AK, Pethe K, Dick T, Wenk MR. Sensitive profiling of chemically diverse bioactive lipids. Journal of Lipid Research. 48: 1976-84. PMID 17565170 DOI: 10.1194/Jlr.M700060-Jlr200  0.072
2013 Biukovic G, Basak S, Manimekalai MS, Rishikesan S, Roessle M, Dick T, Rao SP, Hunke C, Grüber G. Variations of subunit {varepsilon} of the Mycobacterium tuberculosis F1Fo ATP synthase and a novel model for mechanism of action of the tuberculosis drug TMC207. Antimicrobial Agents and Chemotherapy. 57: 168-76. PMID 23089752 DOI: 10.1128/AAC.01039-12  0.07
2022 Li M, Yamada Y, Rodriguez GM, Dick T, Go ML. Redox Cycling Dioxonaphthoimidazoliums Disrupt Iron Homeostasis in Mycobacterium bovis Bacillus Calmette-Guérin. Microbiology Spectrum. e0197022. PMID 36377959 DOI: 10.1128/spectrum.01970-22  0.069
2020 Li M, Nyantakyi SA, Go ML, Dick T. Resistance against membrane-inserting MmpL3 inhibitor through upregulation of MmpL5 in . Antimicrobial Agents and Chemotherapy. PMID 32958714 DOI: 10.1128/AAC.01100-20  0.068
2022 Sarathy JP, Zimmerman MD, Gengenbacher M, Dartois V, Dick T. Mycobacterium tuberculosis DprE1 Inhibitor OPC-167832 Is Active against Mycobacterium abscessus . Antimicrobial Agents and Chemotherapy. e0123722. PMID 36350151 DOI: 10.1128/aac.01237-22  0.067
2018 Bogdanović N, Sundararaman L, Kamariah N, Tyagi A, Bhushan S, Ragunathan P, Shin J, Dick T, Grüber G. Structure and function of Mycobacterium-specific components of F-ATP synthase subunits α and ε. Journal of Structural Biology. PMID 30342092 DOI: 10.1016/j.jsb.2018.10.006  0.066
2013 Kondreddi RR, Jiricek J, Rao SP, Lakshminarayana SB, Camacho LR, Rao R, Herve M, Bifani P, Ma NL, Kuhen K, Goh A, Chatterjee AK, Dick T, Diagana TT, Manjunatha UH, et al. Design, synthesis, and biological evaluation of indole-2-carboxamides: a promising class of antituberculosis agents. Journal of Medicinal Chemistry. 56: 8849-59. PMID 24090347 DOI: 10.1021/Jm4012774  0.065
2017 Yang X, Wedajo W, Yamada Y, Dahlroth SL, Neo JJ, Dick T, Chui WK. 1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity. European Journal of Medicinal Chemistry. 144: 262-276. PMID 29274493 DOI: 10.1016/j.ejmech.2017.12.017  0.064
2013 Cellitti SE, Shaffer J, Jones DH, Mukherjee T, Gurumurthy M, Bursulaya B, Boshoff HI, Choi I, Nayyar A, Lee YS, Cherian J, Niyomrattanakit P, Dick T, Manjunatha UH, Barry CE, et al. Structure of Ddn, the Deazaflavin-Dependent Nitroreductase from Mycobacterium tuberculosis Involved in Bioreductive Activation of PA-824. Structure (London, England : 1993). 21: 191. PMID 28903033 DOI: 10.1016/j.str.2012.12.012  0.063
1979 Silva JE, Dick TE, Larsen PR. The contribution of local tissue thyroxine monodeiodination to the nuclear 3,5,3'-triiodothyronine in pituitary, liver, and kidney of euthyroid rats. Endocrinology. 103: 1196-207. PMID 217671 DOI: 10.1210/ENDO-103-4-1196  0.063
2019 Saw WG, Wong CF, Dick T, Grüber G. Overexpression, purification, enzymatic and microscopic characterization of recombinant mycobacterial F-ATP synthase. Biochemical and Biophysical Research Communications. PMID 31761325 DOI: 10.1016/j.bbrc.2019.11.098  0.062
2008 Pichota A, Duraiswamy J, Yin Z, Keller TH, Alam J, Liung S, Lee G, Ding M, Wang G, Chan WL, Schreiber M, Ma I, Beer D, Ngew X, Mukherjee K, ... ... Dick T, et al. Peptide deformylase inhibitors of Mycobacterium tuberculosis: synthesis, structural investigations, and biological results. Bioorganic & Medicinal Chemistry Letters. 18: 6568-72. PMID 19008098 DOI: 10.1016/j.bmcl.2008.10.040  0.062
2022 Aragaw WW, Cotroneo N, Stokes S, Pucci M, Critchley I, Gengenbacher M, Dick T. Resistance against DNA Gyrase Inhibitor SPR719 in Mycobacterium avium and Mycobacterium abscessus. Microbiology Spectrum. 10: e0132121. PMID 35019671 DOI: 10.1128/spectrum.01321-21  0.062
2017 Gopal P, Nartey W, Ragunathan P, Sarathy JP, Kaya F, Yee M, Setzer C, Manimekalai MSS, Dartois V, Grüber G, Dick T. Pyrazinoic acid inhibits mycobacterial coenzyme A biosynthesis by binding to aspartate decarboxylase PanD. Acs Infectious Diseases. PMID 28991455 DOI: 10.1021/acsinfecdis.7b00079  0.061
2010 Tan MP, Sequeira P, Lin WW, Phong WY, Cliff P, Ng SH, Lee BH, Camacho L, Schnappinger D, Ehrt S, Dick T, Pethe K, Alonso S. Nitrate respiration protects hypoxic Mycobacterium tuberculosis against acid- and reactive nitrogen species stresses. Plos One. 5: e13356. PMID 21048946 DOI: 10.1371/Journal.Pone.0013356  0.061
2022 Dartois V, Dick T. Drug development challenges in nontuberculous mycobacterial lung disease: TB to the rescue. The Journal of Experimental Medicine. 219. PMID 35543723 DOI: 10.1084/jem.20220445  0.059
2013 Rao SP, Lakshminarayana SB, Kondreddi RR, Herve M, Camacho LR, Bifani P, Kalapala SK, Jiricek J, Ma NL, Tan BH, Ng SH, Nanjundappa M, Ravindran S, Seah PG, Thayalan P, ... ... Dick T, et al. Indolcarboxamide is a preclinical candidate for treating multidrug-resistant tuberculosis. Science Translational Medicine. 5: 214ra168. PMID 24307692 DOI: 10.1126/Scitranslmed.3007355  0.059
2016 Wu ML, Gengenbacher M, Chung JC, Chen SL, Mollenkopf HJ, Kaufmann SH, Dick T. Developmental transcriptome of resting cell formation in Mycobacterium smegmatis. Bmc Genomics. 17: 837. PMID 27784279 DOI: 10.1186/S12864-016-3190-4  0.058
2009 Barry CE, Boshoff HI, Dartois V, Dick T, Ehrt S, Flynn J, Schnappinger D, Wilkinson RJ, Young D. The spectrum of latent tuberculosis: rethinking the biology and intervention strategies. Nature Reviews. Microbiology. 7: 845-55. PMID 19855401 DOI: 10.1038/Nrmicro2236  0.058
2016 Kundu S, Biukovic G, Grüber G, Dick T. Bedaquiline targets the ϵ subunit of mycobacterial F-ATP synthase. Antimicrobial Agents and Chemotherapy. PMID 27620476 DOI: 10.1128/AAC.01291-16  0.057
2013 Phong WY, Lin W, Rao SP, Dick T, Alonso S, Pethe K. Characterization of phosphofructokinase activity in Mycobacterium tuberculosis reveals that a functional glycolytic carbon flow is necessary to limit the accumulation of toxic metabolic intermediates under hypoxia. Plos One. 8: e56037. PMID 23409118 DOI: 10.1371/Journal.Pone.0056037  0.057
2006 Teo JW, Thayalan P, Beer D, Yap AS, Nanjundappa M, Ngew X, Duraiswamy J, Liung S, Dartois V, Schreiber M, Hasan S, Cynamon M, Ryder NS, Yang X, Weidmann B, ... ... Dick T, et al. Peptide deformylase inhibitors as potent antimycobacterial agents. Antimicrobial Agents and Chemotherapy. 50: 3665-73. PMID 16966397 DOI: 10.1128/AAC.00555-06  0.056
2010 Dick T, Manjunatha U, Kappes B, Gengenbacher M. Vitamin B6 biosynthesis is essential for survival and virulence of Mycobacterium tuberculosis. Molecular Microbiology. 78: 980-8. PMID 20815826 DOI: 10.1111/j.1365-2958.2010.07381.x  0.055
2023 Lang M, Ganapathy US, Mann L, Abdelaziz R, Seidel RW, Goddard R, Sequenzia I, Hoenke S, Schulze P, Aragaw WW, Csuk R, Dick T, Richter A. Synthesis and Characterization of Phenylalanine Amides Active against and Other Mycobacteria. Journal of Medicinal Chemistry. PMID 37001025 DOI: 10.1021/acs.jmedchem.3c00009  0.055
2021 Aragaw WW, Roubert C, Fontaine E, Lagrange S, Zimmerman MD, Dartois V, Gengenbacher M, Dick T. Cyclohexyl-griselimycin is active against in mice. Antimicrobial Agents and Chemotherapy. AAC0140021. PMID 34723632 DOI: 10.1128/AAC.01400-21  0.054
2008 Kurabachew M, Lu SH, Krastel P, Schmitt EK, Suresh BL, Goh A, Knox JE, Ma NL, Jiricek J, Beer D, Cynamon M, Petersen F, Dartois V, Keller T, Dick T, et al. Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis. The Journal of Antimicrobial Chemotherapy. 62: 713-9. PMID 18587134 DOI: 10.1093/jac/dkn269  0.054
2014 Gopal P, Dick T. Reactive dirty fragments: implications for tuberculosis drug discovery. Current Opinion in Microbiology. 21: 7-12. PMID 25078318 DOI: 10.1016/j.mib.2014.06.015  0.053
2017 Li M, Nyantakyi SA, Gopal P, Aziz DB, Dick T, Go ML. Indolylalkyltriphenylphosphonium Analogues Are Membrane-Depolarizing Mycobactericidal Agents. Acs Medicinal Chemistry Letters. 8: 1165-1170. PMID 29152049 DOI: 10.1021/acsmedchemlett.7b00287  0.053
2015 Gopal P, Dick T. The new tuberculosis drug Perchlozone® shows cross-resistance with thiacetazone. International Journal of Antimicrobial Agents. 45: 430-3. PMID 25704063 DOI: 10.1016/j.ijantimicag.2014.12.026  0.053
2016 Gopal P, Yee M, Sarathy J, Low JL, Sarathy JP, Kaya F, Dartois V, Gengenbacher M, Dick T. Pyrazinamide Resistance Is Caused by Two Distinct Mechanisms: Prevention of Coenzyme A Depletion and Loss of Virulence Factor Synthesis. Acs Infectious Diseases. 2: 616-626. PMID 27759369 DOI: 10.1021/acsinfecdis.6b00070  0.053
2013 Chung BK, Dick T, Lee DY. In silico analyses for the discovery of tuberculosis drug targets. The Journal of Antimicrobial Chemotherapy. 68: 2701-9. PMID 23838951 DOI: 10.1093/jac/dkt273  0.053
2020 Brzostek J, Fatin A, Chua WH, Tan HY, Dick T, Gascoigne NRJ. Single Cell Analysis of Drug Susceptibility of During Macrophage Infection. Antibiotics (Basel, Switzerland). 9. PMID 33080864 DOI: 10.3390/antibiotics9100711  0.052
2022 Negatu DA, Zimmerman MD, Dartois V, Dick T. Strongly Bactericidal All-Oral β-Lactam Combinations for the Treatment of Mycobacterium abscessus Lung Disease. Antimicrobial Agents and Chemotherapy. e0079022. PMID 36047786 DOI: 10.1128/aac.00790-22  0.052
2021 Dartois V, Dick T. A Ginger Root or Plum Model for the Tuberculosis "Granuloma"? American Journal of Respiratory and Critical Care Medicine. 204: 505-507. PMID 34153207 DOI: 10.1164/rccm.202104-1052ED  0.051
2017 Negatu DA, Liu JJJ, Zimmerman M, Kaya F, Dartois V, Aldrich CC, Gengenbacher M, Dick T. Whole cell screen of fragment library identifies gut microbiota metabolite indole propionic acid as antitubercular. Antimicrobial Agents and Chemotherapy. PMID 29229639 DOI: 10.1128/Aac.01571-17  0.05
2008 Rao SP, Camacho L, Huat Tan B, Boon C, Russel DG, Dick T, Pethe K. Recombinase-based reporter system and antisense technology to study gene expression and essentiality in hypoxic nonreplicating mycobacteria. Fems Microbiology Letters. 284: 68-75. PMID 18544099 DOI: 10.1111/J.1574-6968.2008.01193.X  0.05
2022 Ganapathy US, Dick T. Why Matter Matters: Fast-Tracking Drug Discovery. Molecules (Basel, Switzerland). 27. PMID 36296540 DOI: 10.3390/molecules27206948  0.048
2017 Gopal P, Tasneen R, Yee M, Lanoix JP, Sarathy JP, Rasic G, Li L, Dartois V, Nuermberger E, Dick T. In vivo-selected pyrazinoic acid-resistant M. tuberculosis strains harbor missense mutations in the aspartate decarboxylase PanD and the unfoldase ClpC1. Acs Infectious Diseases. PMID 28271875 DOI: 10.1021/acsinfecdis.7b00017  0.047
2019 Williams JT, Haiderer ER, Coulson GB, Conner KN, Ellsworth E, Chen C, Alvarez-Cabrera N, Li W, Jackson M, Dick T, Abramovitch RB. Identification of new MmpL3 inhibitors by untargeted and targeted mutant screens defines MmpL3 domains with differential resistance. Antimicrobial Agents and Chemotherapy. PMID 31405862 DOI: 10.1128/Aac.00547-19  0.047
2020 Gopal P, Sarathy JP, Yee M, Ragunathan P, Shin J, Bhushan S, Zhu J, Akopian T, Kandror O, Lim TK, Gengenbacher M, Lin Q, Rubin EJ, Grüber G, Dick T. Pyrazinamide triggers degradation of its target aspartate decarboxylase. Nature Communications. 11: 1661. PMID 32245967 DOI: 10.1038/S41467-020-15516-1  0.047
2017 Yee M, Klinzing D, Wei JR, Gengenbacher M, Rubin EJ, Dick T. Draft Genome Sequence of Mycobacterium abscessus Bamboo. Genome Announcements. 5. PMID 28522728 DOI: 10.1128/Genomea.00388-17  0.046
2013 Gurumurthy M, Rao M, Mukherjee T, Rao SP, Boshoff HI, Dick T, Barry CE, Manjunatha UH. A novel F(420) -dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents. Molecular Microbiology. 87: 744-55. PMID 23240649 DOI: 10.1111/mmi.12127  0.046
2019 Gopal P, Dick T. Targeted protein degradation in antibacterial drug discovery? Progress in Biophysics and Molecular Biology. 152: 10-14. PMID 31738980 DOI: 10.1016/j.pbiomolbio.2019.11.005  0.045
2013 Sarathy J, Dartois V, Dick T, Gengenbacher M. Reduced drug uptake in phenotypically resistant nutrient-starved nonreplicating Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 57: 1648-53. PMID 23335744 DOI: 10.1128/AAC.02202-12  0.045
2018 Wu ML, Aziz DB, Dartois V, Dick T. NTM drug discovery: status, gaps and the way forward. Drug Discovery Today. 23: 1502-1519. PMID 29635026 DOI: 10.1016/j.drudis.2018.04.001  0.045
2015 Dick T. Alternative approaches to well-being and engagement in Vanuatu. Australasian Psychiatry : Bulletin of Royal Australian and New Zealand College of Psychiatrists. 23: 52-4. PMID 26634672 DOI: 10.1177/1039856215608290  0.043
2023 Negatu DA, Aragaw WW, Dartois V, Dick T. Characterization of Resistance to Linezolid in Mycobacterium abscessus. Microbiology Spectrum. 11: e0219923. PMID 37458588 DOI: 10.1128/spectrum.02199-23  0.043
2016 Mukherjee D, Zou H, Liu S, Beuerman R, Dick T. Membrane-targeting AM-0016 kills mycobacterial persisters and shows low propensity for resistance development. Future Microbiology. PMID 27158932 DOI: 10.2217/fmb-2015-0015  0.042
2023 Sarathy JP, Aldrich CC, Go ML, Dick T. PROTAC antibiotics: the time is now. Expert Opinion On Drug Discovery. 18: 363-370. PMID 37027333 DOI: 10.1080/17460441.2023.2178413  0.041
2022 Remm S, Earp JC, Dick T, Dartois V, Seeger MA. Critical discussion on drug efflux in Mycobacterium tuberculosis. Fems Microbiology Reviews. 46. PMID 34637511 DOI: 10.1093/femsre/fuab050  0.041
2017 Yee M, Klinzing D, Wei JR, Gengenbacher M, Rubin EJ, Chien JY, Hsueh PR, Dick T. Draft Genome Sequence of Mycobacterium avium 11. Genome Announcements. 5. PMID 28798178 DOI: 10.1128/Genomea.00766-17  0.041
2021 Tan YJ, Li M, Gunawan GA, Nyantakyi SA, Dick T, Go ML, Lam Y. Amide-Amine Replacement in Indole-2-carboxamides Yields Potent Mycobactericidal Agents with Improved Water Solubility. Acs Medicinal Chemistry Letters. 12: 704-712. PMID 34055215 DOI: 10.1021/acsmedchemlett.0c00588  0.04
2015 Kana BD, Karakousis PC, Parish T, Dick T. Future target-based drug discovery for tuberculosis? Tuberculosis (Edinburgh, Scotland). 94: 551-6. PMID 25458615 DOI: 10.1016/j.tube.2014.10.003  0.04
1978 Silva JE, Kaplan MM, Cheron RG, Dick TE, Larsen PR. Thyroxine to 3,5,3'-triiodothyronine conversion by rat anterior pituitary and liver. Metabolism: Clinical and Experimental. 27: 1601-7. PMID 703602 DOI: 10.1016/0026-0495(78)90282-2  0.039
2015 Lakshminarayana SB, Huat TB, Ho PC, Manjunatha UH, Dartois V, Dick T, Rao SP. Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents. The Journal of Antimicrobial Chemotherapy. 70: 857-67. PMID 25587994 DOI: 10.1093/jac/dku457  0.037
2012 Robertson BD, Altmann D, Barry C, Bishai B, Cole S, Dick T, Duncan K, Dye C, Ehrt S, Esmail H, Flynn J, Hafner R, Handley G, Hanekom W, van Helden P, et al. Detection and treatment of subclinical tuberculosis. Tuberculosis (Edinburgh, Scotland). 92: 447-52. PMID 22819716 DOI: 10.1016/J.Tube.2012.06.004  0.036
2015 Gengenbacher M, Dick T. Antibacterial drug discovery: doing it right. Chemistry & Biology. 22: 5-6. PMID 25615950 DOI: 10.1016/j.chembiol.2014.12.005  0.033
2004 Sinha I, Dick T. Role for malonyl coenzyme A:acyl carrier protein transacylase (MCAT) in the growth-inhibitory effect of the calmodulin antagonist trifluoperazine in Mycobacterium bovis BCG. The Journal of Antimicrobial Chemotherapy. 53: 1072-5. PMID 15150177 DOI: 10.1093/jac/dkh241  0.032
2003 Sinha I, Boon C, Dick T. Apparent growth phase-dependent phosphorylation of malonyl coenzyme A:acyl carrier protein transacylase (MCAT), a major fatty acid synthase II component in Mycobacterium bovis BCG. Fems Microbiology Letters. 227: 141-7. PMID 14568160 DOI: 10.1016/S0378-1097(03)00664-5  0.031
2016 Yee M, Gopal P, Dick T. Missense mutations in the unfoldase ClpC1 of the caseinolytic protease complex are associated with pyrazinamide resistance in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. PMID 27872068 DOI: 10.1128/AAC.02342-16  0.03
2015 Wu ML, Dick T. Metabolic flexibility and morphological plasticity in mycobacteria. Future Microbiology. 10: 449-52. PMID 25865185 DOI: 10.2217/fmb.14.151  0.026
2006 Manjunatha UH, Boshoff H, Dowd CS, Zhang L, Albert TJ, Norton JE, Daniels L, Dick T, Pang SS, Barry CE. Identification of a nitroimidazo-oxazine-specific protein involved in PA-824 resistance in Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 431-6. PMID 16387854 DOI: 10.1073/pnas.0508392103  0.026
2004 Teng R, Dick T. Isoniazid resistance of exponentially growing Mycobacterium smegmatis biofilm culture. Fems Microbiology Letters. 227: 171-4. PMID 14592705 DOI: 10.1016/S0378-1097(03)00584-6  0.024
1977 Quay SC, Dick TE, Oxender DL. Role of transport systems in amino acid metabolism: leucine toxicity and the branched-chain amino acid transport systems. Journal of Bacteriology. 129: 1257-1265. DOI: 10.1128/JB.129.3.1257-1265.1977  0.021
2020 Yam YK, Alvarez N, Go ML, Dick T. Extreme Drug Tolerance of "Persisters". Frontiers in Microbiology. 11: 359. PMID 32194537 DOI: 10.3389/fmicb.2020.00359  0.02
2018 Chen H, Nyantakyi SA, Li M, Gopal P, Aziz DB, Yang T, Moreira W, Gengenbacher M, Dick T, Go ML. The Mycobacterial Membrane: A Novel Target Space for Anti-tubercular Drugs. Frontiers in Microbiology. 9: 1627. PMID 30072978 DOI: 10.3389/fmicb.2018.01627  0.014
2020 Safi H, Sherman DR, Dick T, Alland D. Reply to Vargas and Farhat: mutants in human tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32075921 DOI: 10.1073/pnas.1922199117  0.01
2019 Dartois V, Sizemore C, Dick T. Editorial: NTM-The New Uber-Bugs. Frontiers in Microbiology. 10: 1299. PMID 31249560 DOI: 10.3389/fmicb.2019.01299  0.01
2019 Dick T, Dartois V. TB drug susceptibility is more than MIC. Nature Microbiology. 3: 971-972. PMID 30143801 DOI: 10.1038/s41564-018-0226-3  0.01
2011 Dick T, Young D. How antibacterials really work: impact on drug discovery. Future Microbiology. 6: 603-4. PMID 21707306 DOI: 10.2217/fmb.11.26  0.01
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