Lucy E. O'Brien, Ph.D.

University of California, San Francisco, San Francisco, CA 
 2013- Molecular and Cellular Physiology Stanford University School of Medicine, Palo Alto, CA, United States 
cell polarity
"Lucy O'Brien"


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Keith E. Mostov grad student 2001 UCSF
 (Regulatory forces during three-dimensional epithelial morphogenesis.)
David Bilder post-doc 2005-2009 UC Berkeley


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XinXin Du post-doc Stanford (Chemistry Tree)
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O'Brien LE, Bilder D. (2013) Beyond the niche: tissue-level coordination of stem cell dynamics. Annual Review of Cell and Developmental Biology. 29: 107-36
O'Brien LE, Soliman SS, Li X, et al. (2011) Altered modes of stem cell division drive adaptive intestinal growth. Cell. 147: 603-14
Kim M, O'Brien LE, Kwon SH, et al. (2010) STAT1 is required for redifferentiation during Madin-Darby canine kidney tubulogenesis. Molecular Biology of the Cell. 21: 3926-33
O'Brien LE, Yu W, Tang K, et al. (2006) Morphological and biochemical analysis of Rac1 in three-dimensional epithelial cell cultures. Methods in Enzymology. 406: 676-91
Mostov K, Brakeman P, Datta A, et al. (2005) Formation of multicellular epithelial structures. Novartis Foundation Symposium. 269: 193-200; discussion
Yu W, Datta A, Leroy P, et al. (2005) Beta1-integrin orients epithelial polarity via Rac1 and laminin. Molecular Biology of the Cell. 16: 433-45
O'Brien LE, Tang K, Kats ES, et al. (2004) ERK and MMPs sequentially regulate distinct stages of epithelial tubule development. Developmental Cell. 7: 21-32
Zegers MM, O'Brien LE, Yu W, et al. (2003) Epithelial polarity and tubulogenesis in vitro. Trends in Cell Biology. 13: 169-76
Yu W, O'Brien LE, Wang F, et al. (2003) Hepatocyte growth factor switches orientation of polarity and mode of movement during morphogenesis of multicellular epithelial structures. Molecular Biology of the Cell. 14: 748-63
O'Brien LE, Zegers MM, Mostov KE. (2002) Opinion: Building epithelial architecture: insights from three-dimensional culture models. Nature Reviews. Molecular Cell Biology. 3: 531-7
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