Brent Hartman Cochran, Ph.D.
Affiliations: | 1985-1993 | Biology | Massachusetts Institute of Technology, Cambridge, MA, United States |
1993- | Developmental, Molecular, and Chemical Biology | Tufts University School of Medicine, Boston, MA, United States |
Area:
signal transduction, glioblastoma, Jak/STATWebsite:
www.cochranlab.orgGoogle:
"Brent Cochran"Parents
Sign in to add mentorCharles D. Stiles | grad student | 1978-1984 | Dana Farber Cancer Institute (Neurotree) |
Children
Sign in to add traineeJeyhuk Lee | grad student | Tufts Medical School | |
Piali Sengupta | grad student | 1986-1991 | MIT |
Dae-Won Kim | grad student | 1995-2000 | Tufts Medical School |
Liza Konnikova | grad student | 2001-2005 | Tufts Medical School |
Maureen M. Sherry | grad student | 2006-2011 | Sackler School of Graduate Biomedical Sciences (Tufts University) |
Shreya Kulkarni | grad student | 2011-2016 | Sackler School of Graduate Biomedical Sciences (Tufts University) |
Sejuti Senjupta | grad student | 2011-2016 | Sackler School of Graduate Biomedical Sciences (Tufts University) |
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Publications
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Kulkarni S, Goel S, Sengupta S, et al. (2017) A Large-scale RNAi Screen Identifies SGK1 as a Key Survival Kinase for GBM Stem Cells. Molecular Cancer Research : McR |
Sherry-Lynes MM, Sengupta S, Kulkarni S, et al. (2017) Regulation of the JMJD3 (KDM6B) histone demethylase in glioblastoma stem cells by STAT3. Plos One. 12: e0174775 |
Goel-Bhattacharya S, Kulkarni S, Sengupta S, et al. (2014) CS-11 * AN RNAi KINOME SCREEN OF GLIOBLASTOMA STEM CELLS UNDER NORMOXIA AND HYPOXIA Neuro-Oncology. 16: v53-v53 |
Chakraborty S, Li L, Tang H, et al. (2013) Cytoplasmic TRADD confers a worse prognosis in glioblastoma. Neoplasia (New York, N.Y.). 15: 888-97 |
Sherry MM, Reeves A, Wu JK, et al. (2009) STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells (Dayton, Ohio). 27: 2383-92 |
Simeone-Penney MC, Severgnini M, Rozo L, et al. (2008) PDGF-induced human airway smooth muscle cell proliferation requires STAT3 and the small GTPase Rac1. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L698-704 |
Konnikova L, Simeone MC, Kruger MM, et al. (2005) Signal transducer and activator of transcription 3 (STAT3) regulates human telomerase reverse transcriptase (hTERT) expression in human cancer and primary cells. Cancer Research. 65: 6516-20 |
Konnikova L, Kotecki M, Kruger MM, et al. (2003) Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. Bmc Cancer. 3: 23 |
Kim DW, Cochran BH. (2001) JAK2 activates TFII-I and regulates its interaction with extracellular signal-regulated kinase. Molecular and Cellular Biology. 21: 3387-97 |
Simon AR, Vikis HG, Stewart S, et al. (2000) Regulation of STAT3 by direct binding to the Rac1 GTPase. Science (New York, N.Y.). 290: 144-7 |