Christine A. Parachoniak, Ph.D.

2012 Biochemistry McGill University, Montreal, QC, Canada 
Signal Transduction
"Christine Parachoniak"


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Morag Park grad student 2012 McGill
 (Characterization of Met receptor tyrosine kinase-mediated endocytosis and its role in signal transduction and cellular migration.)
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Zaoui K, Duhamel S, Parachoniak CA, et al. (2018) CLIP-170 spatially modulates receptor tyrosine kinase recycling to coordinate cell migration. Traffic (Copenhagen, Denmark)
Ratcliffe CD, Sahgal P, Parachoniak CA, et al. (2016) Regulation of cell migration and β1 integrin trafficking by the endosomal adaptor GGA3. Traffic (Copenhagen, Denmark)
Fitamant J, Kottakis F, Benhamouche S, et al. (2015) YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression. Cell Reports
Saha SK, Parachoniak CA, Ghanta KS, et al. (2014) Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. Nature. 513: 110-4
Lu KV, Chang JP, Parachoniak CA, et al. (2012) VEGF inhibits tumor cell invasion and mesenchymal transition through a MET/VEGFR2 complex. Cancer Cell. 22: 21-35
Parachoniak CA, Park M. (2012) Dynamics of receptor trafficking in tumorigenicity. Trends in Cell Biology. 22: 231-40
Parachoniak CA, Luo Y, Abella JV, et al. (2011) GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration. Developmental Cell. 20: 751-63
Abella JV, Parachoniak CA, Sangwan V, et al. (2010) Dorsal ruffle microdomains potentiate Met receptor tyrosine kinase signaling and down-regulation. The Journal of Biological Chemistry. 285: 24956-67
Parachoniak CA, Park M. (2009) Distinct recruitment of Eps15 via Its coiled-coil domain is required for efficient down-regulation of the met receptor tyrosine kinase. The Journal of Biological Chemistry. 284: 8382-94
Wilson EB, Parachoniak CA, Carpenito C, et al. (2007) Expression of murine killer immunoglobulin-like receptor KIRL1 on CD1d-independent NK1.1(+) T cells. Immunogenetics. 59: 641-51
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