David Pincus, Ph.D.

Affiliations: 
2012 Cell Biology University of California, San Francisco, San Francisco, CA 
Area:
Secretion, UPR
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"David Pincus"

Parents

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Hana El-Samad grad student UCSF
Peter Walter grad student 2012 UCSF
 (Homeostasis in the Unfolded Protein Response.)
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Publications

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Feder ZA, Ali A, Singh A, et al. (2021) Subcellular localization of the J-protein Sis1 regulates the heat shock response. The Journal of Cell Biology. 220
Mace K, Krakowiak J, El-Samad H, et al. (2020) Multi-kinase control of environmental stress responsive transcription. Plos One. 15: e0230246
Zheng X, Beyzavi A, Krakowiak J, et al. (2018) Hsf1 Phosphorylation Generates Cell-to-Cell Variation in Hsp90 Levels and Promotes Phenotypic Plasticity. Cell Reports. 22: 3099-3106
Krakowiak J, Zheng X, Patel N, et al. (2018) Hsf1 and Hsp70 constitute a two-component feedback loop that regulates the yeast heat shock response. Elife. 7
Truttmann MC, Zheng X, Hanke L, et al. (2016) Unrestrained AMPylation targets cytosolic chaperones and activates the heat shock response. Proceedings of the National Academy of Sciences of the United States of America
Zheng X, Krakowiak J, Patel N, et al. (2016) Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation. Elife. 5
Damon JR, Pincus D, Ploegh HL. (2015) tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae. Molecular Biology of the Cell. 26: 270-82
Pincus DL, Chakrabarti S, Thirumalai D. (2015) Helicase Processivity and Not the Unwinding Velocity Exhibits Universal Increase with Force Biophysical Journal. 109: 220-230
van Anken E, Pincus D, Coyle S, et al. (2014) Specificity in endoplasmic reticulum-stress signaling in yeast entails a step-wise engagement of HAC1 mRNA to clusters of the stress sensor Ire1. Elife. 3: e05031
Pincus D, Aranda-Díaz A, Zuleta IA, et al. (2014) Delayed Ras/PKA signaling augments the unfolded protein response. Proceedings of the National Academy of Sciences of the United States of America. 111: 14800-5
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