Zachary E. Perlman, Ph.D.

Affiliations: 
2005 Harvard University, Cambridge, MA, United States 
Area:
Microtubules, Actin, Mitosis, Cell cycle
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"Zachary Perlman"

Parents

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Timothy J. Mitchison grad student 2005 Harvard
 (Using microscopy and automated image analysis to study cell phenotype and drug response.)
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Publications

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Burbank KS, Groen AC, Perlman ZE, et al. (2006) A new method reveals microtubule minus ends throughout the meiotic spindle. The Journal of Cell Biology. 175: 369-75
Perlman ZE, Bock JE, Peterson JR, et al. (2005) Geometric diversity through permutation of backbone configuration in cyclic peptide libraries Bioorganic and Medicinal Chemistry Letters. 15: 5329-5334
Perlman ZE, Mitchison TJ, Mayer TU. (2005) High-content screening and profiling of drug activity in an automated centrosome-duplication assay. Chembiochem : a European Journal of Chemical Biology. 6: 145-51
Valentine MT, Perlman ZE, Mitchison TJ, et al. (2005) Mechanical properties of Xenopus egg cytoplasmic extracts. Biophysical Journal. 88: 680-9
Miyamoto DT, Perlman ZE, Burbank KS, et al. (2004) The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles. The Journal of Cell Biology. 167: 813-8
Eggert US, Kiger AA, Richter C, et al. (2004) Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. Plos Biology. 2: e379
Perlman ZE, Slack MD, Feng Y, et al. (2004) Multidimensional drug profiling by automated microscopy. Science (New York, N.Y.). 306: 1194-8
Shirasu-Hiza M, Perlman ZE, Wittmann T, et al. (2004) Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked. Current Biology : Cb. 14: 1941-5
Mitchison TJ, Maddox P, Groen A, et al. (2004) Bipolarization and poleward flux correlate during Xenopus extract spindle assembly. Molecular Biology of the Cell. 15: 5603-15
Yarrow JC, Perlman ZE, Westwood NJ, et al. (2004) A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods. Bmc Biotechnology. 4: 21
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